Mus musculus

168 known processes

Insr

insulin receptor

(Aliases: IR-B,IR-A,4932439J01Rik,IR,CD220,D630014A15Rik)

Insr biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of carbohydrate biosynthetic processGO:0043255401.000
regulation of glucan biosynthetic processGO:001096271.000
regulation of insulin receptor signaling pathwayGO:0046626211.000
response to peptide hormoneGO:00434341271.000
cellular response to peptideGO:1901653920.999
regulation of glycogen metabolic processGO:0070873130.999
glycogen biosynthetic processGO:0005978140.999
regulation of glucose metabolic processGO:0010906600.999
carbohydrate biosynthetic processGO:0016051740.998
insulin receptor signaling pathwayGO:0008286490.997
glycogen metabolic processGO:0005977320.996
energy reserve metabolic processGO:0006112390.996
cellular response to insulin stimulusGO:0032869780.996
monosaccharide metabolic processGO:00059961060.996
response to peptideGO:19016521360.995
positive regulation of glucose metabolic processGO:0010907210.993
polysaccharide biosynthetic processGO:0000271200.991
regulation of fatty acid metabolic processGO:0019217280.990
negative regulation of cellular response to insulin stimulusGO:1900077160.989
regulation of carbohydrate metabolic processGO:0006109750.989
positive regulation of cellular carbohydrate metabolic processGO:0010676290.987
cellular response to hormone stimulusGO:00328701500.984
regulation of glycogen biosynthetic processGO:000597970.983
glucose metabolic processGO:0006006920.982
energy derivation by oxidation of organic compoundsGO:0015980770.981
cellular response to peptide hormone stimulusGO:0071375920.980
carbohydrate metabolic processGO:00059752300.979
glucan metabolic processGO:0044042320.979
regulation of cellular ketone metabolic processGO:0010565660.977
glucan biosynthetic processGO:0009250140.975
monocarboxylic acid metabolic processGO:00327871910.975
Human
hexose metabolic processGO:0019318980.975
regulation of fatty acid oxidationGO:0046320100.975
oxidation reduction processGO:00551143420.975
lipid biosynthetic processGO:00086101790.974
regulation of steroid biosynthetic processGO:0050810260.973
response to organonitrogen compoundGO:00102432460.969
generation of precursor metabolites and energyGO:00060911030.964
cellular glucan metabolic processGO:0006073320.963
cellular carbohydrate metabolic processGO:00442621190.960
cellular response to organonitrogen compoundGO:00714171450.957
negative regulation of phosphate metabolic processGO:00459361840.955
Mouse Rat
regulation of gluconeogenesisGO:0006111300.955
regulation of polysaccharide biosynthetic processGO:003288570.952
positive regulation of insulin receptor signaling pathwayGO:004662840.950
cellular polysaccharide metabolic processGO:0044264380.948
response to insulinGO:00328681000.946
asymmetric stem cell divisionGO:009872230.940
Fly
positive regulation of fatty acid oxidationGO:004632140.937
negative regulation of phosphorylationGO:00423261660.936
Mouse Rat
glucose importGO:0046323320.936
Human
regulation of kinase activityGO:00435492490.935
Human
lactationGO:0007595250.927
regulation of lipid metabolic processGO:00192161180.925
response to oxygen levelsGO:0070482620.922
Fly
regulation of polysaccharide metabolic processGO:0032881130.918
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.917
protein kinase b signalingGO:0043491740.917
Human Mouse
positive regulation of lipid metabolic processGO:0045834400.916
regulation of cellular carbohydrate metabolic processGO:0010675750.914
regulation of circadian sleep wake cycle sleepGO:004518730.912
Fly
gluconeogenesisGO:0006094390.909
negative regulation of cellular carbohydrate metabolic processGO:0010677190.908
regulation of transferase activityGO:00513382630.908
Human
positive regulation of mapk cascadeGO:00434101700.906
Human Mouse
regulation of feeding behaviorGO:006025930.906
Fly
cellular ketone metabolic processGO:0042180840.904
regulation of cellular amine metabolic processGO:0033238200.903
regulation of cellular response to insulin stimulusGO:1900076300.902
response to extracellular stimulusGO:00099911270.900
Rat Worm
regulation of nitrogen cycle metabolic processGO:190331410.900
negative regulation of hormone secretionGO:0046888200.896
negative regulation of insulin receptor signaling pathwayGO:0046627140.895
response to organic cyclic compoundGO:00140701980.891
Rat Fly
negative regulation of feeding behaviorGO:200025210.889
Fly
response to decreased oxygen levelsGO:0036293590.888
Fly
carbohydrate transportGO:0008643620.888
Human
response to monosaccharideGO:0034284670.886
Rat
mapk cascadeGO:00001652810.883
Human Mouse
polysaccharide metabolic processGO:0005976390.883
cellular homeostasisGO:00197252400.879
male germ line stem cell asymmetric divisionGO:004813320.874
Fly
cation homeostasisGO:00550802120.873
acylglycerol metabolic processGO:0006639550.871
cellular amino acid metabolic processGO:00065201030.871
morphogenesis of a branching structureGO:00017632030.864
cellular lipid metabolic processGO:00442553230.859
regulation of hormone secretionGO:0046883880.851
positive regulation of transferase activityGO:00513471670.851
Human
insulin like growth factor receptor signaling pathwayGO:0048009210.841
negative regulation of cell proliferationGO:00082852960.839
response to starvationGO:0042594650.837
Worm
regulation of sequence specific dna binding transcription factor activityGO:00510901060.834
Mouse
positive regulation of glycogen biosynthetic processGO:004572560.832
regulation of secretionGO:00510462740.829
amine metabolic processGO:0009308450.825
hexose biosynthetic processGO:0019319390.821
metal ion homeostasisGO:00550651890.819
regulation of peptide transportGO:0090087910.818
regulation of circadian rhythmGO:0042752580.817
Fly
circadian rhythmGO:00076231140.802
Fly
positive regulation of cellular amine metabolic processGO:003324050.797
regulation of cellular catabolic processGO:00313292420.792
Human Worm Fly
hormone secretionGO:00468791280.786
negative regulation of kinase activityGO:0033673810.786
reactive oxygen species biosynthetic processGO:190340980.783
fatty acid metabolic processGO:00066311210.780
brown fat cell differentiationGO:0050873360.779
regulation of lipid biosynthetic processGO:0046890540.776
neutral lipid metabolic processGO:0006638570.772
cellular amine metabolic processGO:0044106440.772
regulation of body fluid levelsGO:00508781620.772
regulation of protein kinase activityGO:00458592320.770
Human
cellular metal ion homeostasisGO:00068751510.768
glucose transportGO:0015758560.764
Human
positive regulation of carbohydrate metabolic processGO:0045913300.762
negative regulation of protein phosphorylationGO:00019331260.752
Rat
mitochondrion organizationGO:00070051340.744
circadian regulation of gene expressionGO:0032922480.743
cellular polysaccharide biosynthetic processGO:0033692190.736
cellular response to growth factor stimulusGO:00713631970.733
cellular lipid catabolic processGO:0044242520.725
regulation of cellular amino acid metabolic processGO:000652150.722
blood vessel morphogenesisGO:00485142850.720
positive regulation of vasoconstrictionGO:004590740.716
regulation of mapk cascadeGO:00434082480.709
Human Mouse
intracellular receptor signaling pathwayGO:0030522740.700
lipid transportGO:0006869980.689
cellular chemical homeostasisGO:00550822150.686
fat cell differentiationGO:00454441600.674
Rat
regulation of apoptotic signaling pathwayGO:20012331970.670
negative regulation of phosphorus metabolic processGO:00105631840.670
Mouse Rat
keratinocyte migrationGO:005154630.669
gland developmentGO:00487323300.665
Mouse
response to oxidative stressGO:00069791230.665
Worm Fly
negative regulation of secretionGO:0051048610.664
regulation of peptide hormone secretionGO:0090276750.661
regulation of generation of precursor metabolites and energyGO:0043467380.651
regulation of glutamate metabolic processGO:200021110.647
cellular calcium ion homeostasisGO:00068741190.645
positive regulation of apoptotic process involved in mammary gland involutionGO:006005840.640
cellular ion homeostasisGO:00068731650.633
anion transportGO:00068201770.633
Mouse
regulation of cell migrationGO:00303342190.630
Human
organic hydroxy compound transportGO:0015850930.623
negative regulation of protein metabolic processGO:00512482820.619
Rat
glycerolipid metabolic processGO:00464861220.618
regulation of protein serine threonine kinase activityGO:00719001570.614
Human
mammary gland epithelium developmentGO:0061180650.612
cellular response to alkaline phGO:007146910.612
Mouse
cellular macromolecule catabolic processGO:00442652060.610
response to radiationGO:00093141650.607
peptide hormone secretionGO:00300721090.607
regulation of circadian sleep wake cycleGO:004274930.602
Fly
response to nutrient levelsGO:00316671090.599
Rat Worm
response to light stimulusGO:00094161350.598
positive regulation of cellular amino acid metabolic processGO:004576430.589
negative regulation of carbohydrate metabolic processGO:0045912190.587
alpha amino acid metabolic processGO:1901605590.587
myotube differentiationGO:00149021050.584
Fly
wound healingGO:00420601570.582
triglyceride metabolic processGO:0006641510.582
regulation of secretion by cellGO:19035302490.579
response to bile acidGO:190341210.577
response to growth factorGO:00708481980.574
glycolytic processGO:0006096200.573
Human
steroid metabolic processGO:00082021190.572
regulation of glutamine family amino acid metabolic processGO:000082010.571
lipid oxidationGO:0034440290.567
urogenital system developmentGO:00016552610.558
Mouse
ammonia assimilation cycleGO:001967620.557
macromolecule methylationGO:00434141200.557
epidermis developmentGO:00085441870.554
negative regulation of cellular amino acid metabolic processGO:004576300.553
monocarboxylic acid catabolic processGO:0072329270.551
divalent inorganic cation transportGO:00725111780.537
negative regulation of lipid metabolic processGO:0045833300.535
peptidyl tyrosine phosphorylationGO:00181081430.534
positive regulation of kinase activityGO:00336741550.532
Human
inositol lipid mediated signalingGO:0048017410.526
negative regulation of intracellular signal transductionGO:19025321670.522
Mouse
cell divisionGO:00513011200.519
cellular carbohydrate catabolic processGO:0044275150.517
Human
cellular response to external stimulusGO:0071496880.517
Worm
phosphatidylinositol mediated signalingGO:0048015410.516
cell proliferation in hindbrainGO:0021534100.511
peptidyl amino acid modificationGO:00181933360.508
lipid modificationGO:0030258650.507
positive regulation of cellular catabolic processGO:00313311480.505
Human
regulation of steroid metabolic processGO:0019218390.501
reactive oxygen species metabolic processGO:0072593840.499
Rat Fly
multicellular organism growthGO:00352641610.488
Worm Fly
negative regulation of peptide secretionGO:0002792160.481
connective tissue developmentGO:00614481790.479
cellular response to nutrient levelsGO:0031669640.475
Worm
apoptotic process involved in mammary gland involutionGO:006005740.474
negative regulation of secretion by cellGO:1903531540.472
vitamin d biosynthetic processGO:004236830.472
negative regulation of triglyceride metabolic processGO:009020940.472
negative regulation of transferase activityGO:0051348850.472
urea metabolic processGO:001962730.470
regulation of urea metabolic processGO:003425510.463
lipid catabolic processGO:0016042690.463
cell adhesionGO:00071553290.458
body fluid secretionGO:0007589530.457
apoptotic mitochondrial changesGO:0008637480.457
peptide transportGO:00158331330.456
rhythmic processGO:00485111740.456
Fly
negative regulation of peptide hormone secretionGO:0090278160.455
positive regulation of protein phosphorylationGO:00019342420.453
Human
regulation of the force of heart contraction by chemical signalGO:000305750.452
glucose homeostasisGO:00425931280.448
Human Rat
calcium ion homeostasisGO:00550741270.448
positive regulation of insulin secretionGO:0032024260.444
regulation of peptide secretionGO:0002791770.444
mammary gland lobule developmentGO:0061377220.439
release of cytochrome c from mitochondriaGO:0001836230.436
epithelial tube morphogenesisGO:00605623030.435
response to alcoholGO:0097305480.430
Rat
establishment of protein localization to organelleGO:00725941180.426
Worm
phosphatidylinositol 3 kinase signalingGO:0014065360.425
regulation of hormone levelsGO:00108172110.412
protein localization to nucleusGO:00345041210.412
Worm
mammary gland duct morphogenesisGO:0060603380.410
monosaccharide biosynthetic processGO:0046364440.406
cyclic purine nucleotide metabolic processGO:0052652430.405
peptide secretionGO:00027901140.402
anatomical structure homeostasisGO:00602491450.392
Fly
positive regulation of protein kinase activityGO:00458601440.389
Human
insulin secretionGO:0030073890.386
small molecule catabolic processGO:0044282710.386
negative regulation of gluconeogenesisGO:004572190.382
regulation of triglyceride metabolic processGO:0090207170.381
regulation of epithelial cell proliferationGO:00506781410.380
regulation of reactive oxygen species biosynthetic processGO:190342620.374
divalent inorganic cation homeostasisGO:00725071380.373
cellular glucose homeostasisGO:0001678520.373
regulation of leukocyte proliferationGO:00706631210.372
positive regulation of protein modification processGO:00314012990.372
Human
positive regulation of nervous system developmentGO:00519622210.371
positive regulation of fat cell differentiationGO:0045600320.371
regulation of vitamin d biosynthetic processGO:006055610.370
small gtpase mediated signal transductionGO:0007264970.369
response to transforming growth factor betaGO:0071559880.369
protein localization to organelleGO:00333651850.368
Worm
regulation of fat cell differentiationGO:0045598810.368
response to ammonium ionGO:0060359210.362
Fly
lymphocyte apoptotic processGO:0070227540.361
regulation of map kinase activityGO:00434051200.361
Human
regulation of leukocyte differentiationGO:19021051590.360
regulation of androgen receptor signaling pathwayGO:006076530.360
regulation of ion transportGO:00432692150.355
Mouse
branching morphogenesis of an epithelial tubeGO:00487541590.354
response to alkaloidGO:0043279340.353
Fly
forebrain developmentGO:00309003020.352
fat soluble vitamin biosynthetic processGO:004236240.345
positive regulation of protein serine threonine kinase activityGO:00719021060.344
Human
fatty acid catabolic processGO:0009062250.342
mammary gland involutionGO:006005690.342
cerebellar granule cell precursor proliferationGO:0021930100.341
nitric oxide biosynthetic processGO:0006809250.340
Human
negative regulation of molecular functionGO:00440922580.340
Mouse Rat
positive regulation of map kinase activityGO:0043406840.336
Human
monosaccharide transportGO:0015749580.330
Human
carbohydrate homeostasisGO:00335001280.329
Human Rat
response to hypoxiaGO:0001666580.326
memoryGO:0007613580.324
positive regulation of cell migrationGO:00303351090.323
Human
carbohydrate derivative biosynthetic processGO:19011371830.321
Rat
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.316
Mouse
negative regulation of apoptotic signaling pathwayGO:20012341040.316
reactive nitrogen species metabolic processGO:200105700.314
intracellular steroid hormone receptor signaling pathwayGO:0030518290.311
heart contractionGO:0060047930.310
prostate gland developmentGO:0030850480.310
Mouse
regulation of appetiteGO:0032098120.310
multi organism reproductive behaviorGO:0044705290.309
Fly
white fat cell differentiationGO:0050872150.306
carbohydrate catabolic processGO:0016052320.304
Human
myeloid cell differentiationGO:00300992330.301
regulation of system processGO:00440572000.301
positive regulation of apoptotic process involved in morphogenesisGO:190233940.300
telencephalon developmentGO:00215371860.299
fatty acid oxidationGO:0019395280.298
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.298
regulation of t cell activationGO:00508631700.297
hindbrain developmentGO:00309021280.293
germ line stem cell divisionGO:004207820.289
Fly
regulation of erk1 and erk2 cascadeGO:0070372710.288
Mouse
nuclear transportGO:00511691390.287
Worm
regulation of cell cycleGO:00517262810.282
cellular response to transforming growth factor beta stimulusGO:0071560880.280
b cell proliferationGO:0042100530.280
regulation of cell activationGO:00508652890.277
learning or memoryGO:00076111480.274
positive regulation of phosphatidylinositol 3 kinase signalingGO:0014068200.274
leukocyte proliferationGO:00706611720.273
protein catabolic processGO:00301632210.266
cognitionGO:00508901490.265
epithelial cell proliferationGO:00506731740.265
positive regulation of mammary gland involutionGO:190352140.260
appendage developmentGO:00487361660.259
fatty acid beta oxidationGO:0006635160.257
regulation of metal ion transportGO:00109591060.256
positive regulation of cell developmentGO:00107202370.255
g protein coupled receptor signaling pathwayGO:00071862430.251
Human
positive regulation of secretionGO:00510471300.251
cellular divalent inorganic cation homeostasisGO:00725031270.251
negative regulation of release of cytochrome c from mitochondriaGO:009020160.250
circulatory system processGO:00030131970.249
prostate gland epithelium morphogenesisGO:0060740310.245
Mouse
protein autophosphorylationGO:0046777610.244
erk1 and erk2 cascadeGO:0070371770.242
Mouse
t cell proliferationGO:00420981200.242
adult behaviorGO:00305341350.242
regulation of protein kinase b signalingGO:0051896560.241
Human Mouse
embryonic placenta developmentGO:0001892980.239
cellular amide metabolic processGO:0043603580.236
feeding behaviorGO:0007631620.235
Fly
leukocyte apoptotic processGO:0071887710.235
maintenance of locationGO:0051235890.234
Worm
negative regulation of cytokine productionGO:0001818840.230
hexose transportGO:0008645560.230
Human
t cell activationGO:00421102890.230
cellular response to cytokine stimulusGO:00713451890.229
organic acid catabolic processGO:0016054510.228
modification dependent protein catabolic processGO:00199411330.228
response to foodGO:0032094170.227
amide transportGO:00428861380.227
positive regulation of secretion by cellGO:19035321140.227
cation transportGO:00068123990.225
muscle cell differentiationGO:00426922610.224
Fly
organophosphate biosynthetic processGO:00904071220.224
multicellular organismal agingGO:0010259240.222
Worm Fly
regulation of fatty acid beta oxidationGO:003199810.222
carboxylic acid catabolic processGO:0046395510.221
methylationGO:00322591340.221
regulation of phosphatidylinositol 3 kinase signalingGO:0014066300.219
branching involved in mammary gland duct morphogenesisGO:0060444270.219
positive regulation of gluconeogenesisGO:0045722110.219
regulation of lymphocyte activationGO:00512492400.219
response to cocaineGO:0042220140.219
Fly
negative regulation of cellular amine metabolic processGO:003323910.216
leukocyte activation involved in immune responseGO:00023661260.216
morphogenesis of a branching epitheliumGO:00611381930.215
regulation of leukocyte apoptotic processGO:2000106560.215
blood circulationGO:00080151950.215
g protein coupled acetylcholine receptor signaling pathwayGO:000721340.211
sulfur compound metabolic processGO:00067901000.211
steroid biosynthetic processGO:0006694470.210
regulation of mammary gland involutionGO:190351940.210
ion transmembrane transportGO:00342203610.208
intrinsic apoptotic signaling pathwayGO:00971931320.208
positive regulation of t cell activationGO:00508701010.207
sensory perception of umami tasteGO:005091740.206
locomotory behaviorGO:00076261950.206
Fly
positive regulation of cell deathGO:00109422240.205
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.203
nitric oxide metabolic processGO:0046209250.202
Human
cellular protein catabolic processGO:00442571550.202
circadian behaviorGO:0048512130.198
Fly
tissue remodelingGO:00487711020.197
cellular response to bile acidGO:190341310.193
regulation of membrane potentialGO:00423911920.192
regulation of glucose importGO:0046324260.192
Human
glycoprotein metabolic processGO:00091001160.192
Rat
negative regulation of blood pressureGO:0045776220.192
exocrine pancreas developmentGO:003101770.192
positive regulation of peptide secretionGO:0002793330.191
cellular response to lipidGO:00713961450.191
negative regulation of mapk cascadeGO:0043409650.190
Mouse
cellular response to abiotic stimulusGO:0071214560.190
Mouse
negative regulation of cellular protein metabolic processGO:00322692470.189
Rat
neuropeptide signaling pathwayGO:0007218190.189
positive regulation of lipid biosynthetic processGO:0046889180.187
nitrogen compound transportGO:00717052710.186
adaptive immune responseGO:00022501550.186
protein targetingGO:00066051430.184
Worm
regulation of release of cytochrome c from mitochondriaGO:0090199110.184
pyruvate metabolic processGO:0006090280.183
Human
vascular process in circulatory systemGO:0003018620.183
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.183
peptidyl tyrosine modificationGO:00182121450.182
neural precursor cell proliferationGO:00613511210.181
transforming growth factor beta receptor signaling pathwayGO:0007179710.181
catecholamine metabolic processGO:0006584300.180
positive regulation of fatty acid metabolic processGO:004592380.180
regulation of catecholamine secretionGO:0050433120.180
regulation of organelle organizationGO:00330432890.179
regulation of proteolysisGO:00301621640.176
positive regulation of lipid catabolic processGO:005099660.174
ras protein signal transductionGO:0007265770.172
glycerolipid biosynthetic processGO:0045017500.170
diacylglycerol metabolic processGO:004633960.168
determination of adult lifespanGO:0008340110.168
Worm Fly
lipid localizationGO:00108761260.167
Worm
apoptotic signaling pathwayGO:00971903060.166
jak stat cascadeGO:0007259420.166
cell fate commitmentGO:00451652100.166
maternal process involved in female pregnancyGO:0060135320.164
response to purine containing compoundGO:0014074280.161
fatty acid transportGO:0015908280.161
regulation of striated muscle cell differentiationGO:0051153810.160
purine ribonucleotide biosynthetic processGO:0009152590.160
anagenGO:0042640130.159
eye photoreceptor cell differentiationGO:0001754410.159
response to corticosteroidGO:0031960200.159
Rat
negative regulation of cell growthGO:0030308440.159
circadian sleep wake cycleGO:004274550.158
Fly
regulation of monooxygenase activityGO:003276870.157
multi multicellular organism processGO:00447061090.156
Fly
skeletal system developmentGO:00015013560.155
regulation of cell motilityGO:20001452360.155
Human
regulation of lymphocyte apoptotic processGO:0070228410.155
cell proliferation in external granule layerGO:0021924100.154
nucleotide metabolic processGO:00091173320.153
positive regulation of glial cell proliferationGO:006025240.153
ribose phosphate biosynthetic processGO:0046390590.151
immune effector processGO:00022523210.150
glutamine metabolic processGO:000654180.149
positive regulation of leukocyte proliferationGO:0070665730.148
positive regulation of lipid kinase activityGO:0090218110.148
regulation of myotube differentiationGO:0010830620.148
negative regulation of protein modification processGO:00314001630.147
Rat
cell maturationGO:00484691270.145
Fly
glutamine family amino acid metabolic processGO:0009064150.144
organic anion transportGO:00157111370.142
divalent metal ion transportGO:00708381720.142
proteolysis involved in cellular protein catabolic processGO:00516031470.141
regulation of myeloid cell differentiationGO:0045637960.141
mammary gland morphogenesisGO:0060443540.141
positive regulation of cytosolic calcium ion concentrationGO:0007204650.141
vasoconstrictionGO:0042310270.140
activation of janus kinase activityGO:004297620.140
g protein coupled receptor internalizationGO:000203130.138
regulation of carbohydrate catabolic processGO:0043470120.138
Human
glutamate metabolic processGO:000653690.135
sensory organ morphogenesisGO:00905962420.135
negative regulation of glycogen biosynthetic processGO:004571910.134
regulation of tor signalingGO:0032006170.134
respiratory tube developmentGO:00303231670.134
lymphocyte homeostasisGO:0002260640.133
positive regulation of cellular response to insulin stimulusGO:190007890.133
response to lipopolysaccharideGO:00324961280.132
associative learningGO:0008306610.132
regulation of receptor activityGO:0010469410.131
cellular response to hypoxiaGO:0071456170.131
response to endoplasmic reticulum stressGO:0034976530.130
germline stem cell asymmetric divisionGO:009872820.129
Fly
positive regulation of cell motilityGO:20001471160.129
Human
regulation of bindingGO:00510981110.129
cell substrate adhesionGO:00315891300.129
male gamete generationGO:00482322850.129
Mouse Fly
visual learningGO:0008542440.126
lung epithelium developmentGO:0060428370.126
regulation of neuron differentiationGO:00456642810.126
negative regulation of tyrosine phosphorylation of stat proteinGO:004253230.126
columnar cuboidal epithelial cell differentiationGO:0002065820.126
Mouse
drug metabolic processGO:001714440.125
regulation of cytokine productionGO:00018172660.125
phospholipid metabolic processGO:0006644870.125
negative regulation of peptidyl tyrosine phosphorylationGO:0050732170.125
acylglycerol biosynthetic processGO:0046463180.123
positive regulation of reactive oxygen species metabolic processGO:2000379110.122
cytoplasmic transportGO:00164822340.121
Worm
ribonucleotide biosynthetic processGO:0009260590.120
dna metabolic processGO:00062593030.120
Human
lung cell differentiationGO:0060479300.120
guanosine containing compound catabolic processGO:19010691440.120
homeostasis of number of cellsGO:00488722100.120
positive regulation of lymphocyte proliferationGO:0050671700.120
cellular response to starvationGO:0009267570.119
Worm
ossificationGO:00015032160.119
cellular response to oxygen levelsGO:0071453200.119
regulation of nucleotide biosynthetic processGO:0030808340.119
central nervous system neuron differentiationGO:00219531620.117
lipid storageGO:0019915360.117
Worm
smooth muscle contractionGO:0006939440.116
digestionGO:0007586400.116
cellular nitrogen compound catabolic processGO:00442702800.115
nitrogen cycle metabolic processGO:007194130.113
regulation of steroid hormone biosynthetic processGO:009003040.112
negative regulation of epithelial cell proliferationGO:0050680640.112
prostate gland stromal morphogenesisGO:006074120.112
organonitrogen compound biosynthetic processGO:19015661920.112
intestinal absorptionGO:0050892130.112
prostate gland morphogenesisGO:0060512320.111
Mouse
epithelial cell migrationGO:0010631630.111
cellular response to oxidative stressGO:0034599760.111

Insr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.895
Human
diabetes mellitusDOID:935100.758
type 2 diabetes mellitusDOID:935200.758
carbohydrate metabolism diseaseDOID:005001300.758
glucose metabolism diseaseDOID:419400.758
acquired metabolic diseaseDOID:006015800.758
inherited metabolic disorderDOID:65500.382
Human
disease of cellular proliferationDOID:1456600.156
carbohydrate metabolic disorderDOID:297800.137
Human