Mus musculus

33 known processes

Kpnb1

karyopherin (importin) beta 1

(Aliases: AA409963,MGC8315,IPOB,Impnb)

Kpnb1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cytoplasmic transportGO:00164822340.729
protein desumoylationGO:001692620.677
Yeast
establishment of protein localization to organelleGO:00725941180.642
translationGO:0006412930.580
protein localization to nucleusGO:00345041210.570
mitotic cell cycle processGO:19030471590.459
Worm Fly
mitotic cell cycleGO:00002781950.449
Worm Fly
cellular macromolecule catabolic processGO:00442652060.441
organelle fissionGO:00482851700.378
Fly
nuclear transportGO:00511691390.373
protein importGO:00170381010.373
nucleocytoplasmic transportGO:00069131390.333
posttranscriptional regulation of gene expressionGO:00106081550.328
intracellular protein transportGO:00068862040.303
single organism nuclear importGO:1902593950.295
positive regulation of cytoplasmic transportGO:1903651400.273
Fly
spermatogenesisGO:00072832840.259
oocyte anterior posterior axis specificationGO:000731420.256
positive regulation of intracellular transportGO:0032388700.253
Fly
protein localization to organelleGO:00333651850.250
microtubule based processGO:00070172360.241
Worm
methylationGO:00322591340.228
regulation of protein import into nucleusGO:0042306520.222
Fly
mrna transportGO:0051028130.218
regulation of intracellular protein transportGO:0033157820.215
Fly
regulation of cell cycleGO:00517262810.188
protein targetingGO:00066051430.176
gene silencing by rnaGO:0031047190.175
aromatic compound catabolic processGO:00194392860.174
ribonucleoprotein complex disassemblyGO:003298830.148
male gamete generationGO:00482322850.146
oocyte constructionGO:000730820.146
regulation of cytoplasmic transportGO:19036491120.137
Fly
regulation of intracellular transportGO:00323861590.135
Fly
nucleobase containing small molecule metabolic processGO:00550863520.134
protein import into nucleusGO:0006606950.133
germ cell developmentGO:00072811850.131
Fly
organic cyclic compound catabolic processGO:19013612950.130
nitrogen compound transportGO:00717052710.126
regulation of translationGO:0006417710.122
regulation of protein targetingGO:1903533610.109
Fly
regulation of mrna stabilityGO:0043488230.106
oocyte axis specificationGO:000730920.103
pole plasm assemblyGO:000731520.101
modification dependent macromolecule catabolic processGO:00436321330.098
dna metabolic processGO:00062593030.098
nucleotide catabolic processGO:00091662170.097
mitotic nuclear divisionGO:0007067480.097
Fly
nuclear importGO:0051170950.094
nuclear transcribed mrna catabolic processGO:0000956160.094
regulation of protein transportGO:00512231630.093
Fly
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112330.093
negative regulation of cellular protein metabolic processGO:00322692470.092
positive regulation of protein localization to nucleusGO:1900182300.088
Fly
protein methylationGO:0006479810.085
nuclear exportGO:0051168340.083
organelle assemblyGO:00709251770.078
nuclear divisionGO:00002801580.078
Fly
meiotic nuclear divisionGO:00071261150.077
rna localizationGO:0006403230.077
nucleus organizationGO:0006997450.075
Yeast
purine nucleoside metabolic processGO:00422782410.074
meiotic cell cycleGO:00513211220.073
cellular response to amino acid stimulusGO:0071230290.070
macromolecule methylationGO:00434141200.070
mrna metabolic processGO:0016071840.069
establishment of rna localizationGO:0051236180.065
nucleoside catabolic processGO:00091642060.063
regionalizationGO:00030023370.063
proteolysis involved in cellular protein catabolic processGO:00516031470.062
ribonucleotide metabolic processGO:00092592910.061
cellular response to cytokine stimulusGO:00713451890.061
regulation of organelle organizationGO:00330432890.059
rna processingGO:00063961050.056
regulation of cellular component biogenesisGO:00440871810.055
cellular nitrogen compound catabolic processGO:00442702800.053
dendrite developmentGO:00163581150.053
ossificationGO:00015032160.052
intracellular mrna localizationGO:000829840.052
response to organonitrogen compoundGO:00102432460.051
regulation of cell cycle processGO:00105641600.051
nucleobase containing compound transportGO:0015931270.050
rna interferenceGO:001624620.049
spermatid differentiationGO:00485151150.049
maternal determination of anterior posterior axis embryoGO:000835820.048
microtubule cytoskeleton organizationGO:00002261570.047
Worm
posttranscriptional gene silencing by rnaGO:0035194100.047
regulation of protein localizationGO:00328802310.046
Fly
positive regulation of intracellular protein transportGO:0090316420.045
Fly
ribose phosphate metabolic processGO:00196932910.045
response to organic cyclic compoundGO:00140701980.045
rna transportGO:0050658180.045
heterocycle catabolic processGO:00467002800.045
purine nucleoside triphosphate metabolic processGO:00091442260.044
cell type specific apoptotic processGO:00972852680.043
nucleic acid transportGO:0050657180.042
ribonucleoside triphosphate catabolic processGO:00092031990.041
mrna export from nucleusGO:0006406110.041
glycosyl compound metabolic processGO:19016572460.040
regulation of nucleocytoplasmic transportGO:0046822730.039
Fly
maintenance of locationGO:0051235890.039
protein complex disassemblyGO:0043241400.039
regulation of cell divisionGO:0051302760.038
regulation of protein localization to nucleusGO:1900180600.038
Fly
positive regulation of nucleocytoplasmic transportGO:0046824300.038
Fly
response to light stimulusGO:00094161350.038
cell recognitionGO:0008037830.038
protein modification by small protein conjugation or removalGO:00706472070.038
Yeast
regulation of cytoskeleton organizationGO:00514931220.038
ribonucleoside metabolic processGO:00091192450.037
nucleoside metabolic processGO:00091162460.037
cellular response to organonitrogen compoundGO:00714171450.037
positive regulation of protein import into nucleusGO:0042307260.037
Fly
negative regulation of protein metabolic processGO:00512482820.037
cellular amino acid metabolic processGO:00065201030.035
regulation of mitotic cell cycleGO:00073461260.035
response to amino acidGO:0043200370.035
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288120.034
rna dependent dna replicationGO:000627830.034
adult behaviorGO:00305341350.033
purine nucleoside triphosphate catabolic processGO:00091462030.033
negative regulation of molecular functionGO:00440922580.033
dna modificationGO:0006304500.032
protein export from nucleusGO:0006611200.032
stem cell developmentGO:00488642190.032
nucleotide metabolic processGO:00091173320.032
stem cell differentiationGO:00488632680.032
regulation of gtp catabolic processGO:00331241130.031
Yeast
receptor mediated endocytosisGO:0006898510.030
mesenchymal cell developmentGO:0014031930.029
epithelial to mesenchymal transitionGO:0001837470.029
actin cytoskeleton organizationGO:00300362200.029
Fly
protein modification by small protein conjugationGO:00324461870.028
gtp catabolic processGO:00061841430.028
multicellular organismal signalingGO:0035637910.028
response to inorganic substanceGO:0010035960.027
regulation of nucleotide metabolic processGO:00061401690.027
Yeast
mitotic sister chromatid segregationGO:0000070140.027
macromolecule catabolic processGO:00090572810.027
cell cell recognitionGO:0009988440.027
dna templated transcriptional preinitiation complex assemblyGO:007089740.026
spindle organizationGO:0007051280.026
Worm
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.026
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.026
response to extracellular stimulusGO:00099911270.025
purine ribonucleoside triphosphate catabolic processGO:00092071990.025
purine nucleoside catabolic processGO:00061522050.025
cell maturationGO:00484691270.025
female gamete generationGO:0007292740.025
Fly
cellular protein complex assemblyGO:00436231160.025
Yeast Fly
protein alkylationGO:0008213810.025
chromatin organizationGO:00063252060.025
regulation of multi organism processGO:00439001110.024
positive regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589920.024
nuclear mrna surveillanceGO:007102810.024
purine nucleotide catabolic processGO:00061952110.024
toxin transportGO:1901998380.024
ribonucleoside triphosphate metabolic processGO:00091992200.024
alpha amino acid metabolic processGO:1901605590.023
development of primary sexual characteristicsGO:00451371430.023
mrna catabolic processGO:0006402220.023
metaphase plate congressionGO:005131020.023
regulation of rna splicingGO:0043484370.023
regulation of rna stabilityGO:0043487260.023
mesenchyme developmentGO:00604851520.023
ribonucleotide catabolic processGO:00092612080.023
regulation of cell morphogenesis involved in differentiationGO:00107691510.022
response to radiationGO:00093141650.022
organophosphate catabolic processGO:00464342320.022
regulation of protein catabolic processGO:00421761080.022
cellular response to acid chemicalGO:0071229680.022
nucleoside phosphate catabolic processGO:19012922220.022
chromosome segregationGO:0007059480.022
body morphogenesisGO:0010171450.022
regulation of proteolysisGO:00301621640.022
adult locomotory behaviorGO:0008344910.021
nucleoside phosphate metabolic processGO:00067533380.021
oogenesisGO:0048477560.021
Fly
guanosine containing compound catabolic processGO:19010691440.021
glycosyl compound catabolic processGO:19016582060.021
regulation of cell projection organizationGO:00313442060.020
sperm egg recognitionGO:0035036370.020
placenta developmentGO:00018901400.020
response to alkaloidGO:0043279340.020
response to oxidative stressGO:00069791230.020
regulation of establishment of protein localizationGO:00702011810.020
Fly
oocyte differentiationGO:0009994350.020
cellular protein catabolic processGO:00442571550.020
response to acid chemicalGO:00011011110.020
b cell activationGO:00421131610.020
muscle system processGO:00030121410.020
ubiquitin dependent protein catabolic processGO:00065111290.019
cell growthGO:00160491300.019
mesenchymal cell differentiationGO:00487621070.019
cardiac muscle contractionGO:0060048320.019
purine ribonucleoside catabolic processGO:00461302050.019
regulation of cell motilityGO:20001452360.019
positive regulation of immune effector processGO:00026991070.019
regulation of mitotic cell cycle phase transitionGO:1901990730.019
response to nutrient levelsGO:00316671090.018
muscle contractionGO:00069361010.018
purine containing compound metabolic processGO:00725213110.018
purine containing compound catabolic processGO:00725232130.018
purine ribonucleotide metabolic processGO:00091502900.018
cell divisionGO:00513011200.018
skin developmentGO:00435882200.018
protein dna complex subunit organizationGO:0071824280.018
organelle localizationGO:00516401790.018
regulation of protein modification by small protein conjugation or removalGO:1903320570.018
Yeast
nucleoside triphosphate metabolic processGO:00091412300.018
digestive system developmentGO:00551232000.018
regulation of nuclear divisionGO:0051783560.018
rna export from nucleusGO:0006405150.017
purine ribonucleotide catabolic processGO:00091542080.017
regulation of protein complex assemblyGO:0043254830.017
developmental maturationGO:00217001930.017
posttranscriptional gene silencingGO:0016441100.017
photoreceptor cell developmentGO:0042461400.017
response to insulinGO:00328681000.017
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.016
positive regulation of cell cycleGO:0045787920.016
wnt signaling pathwayGO:00160551880.016
oxidation reduction processGO:00551143420.016
carbohydrate derivative catabolic processGO:19011362310.016
reactive nitrogen species metabolic processGO:200105700.016
regulation of cell cycle phase transitionGO:1901987770.016
urogenital system developmentGO:00016552610.016
regulation of neuron projection developmentGO:00109751690.016
positive regulation of hydrolase activityGO:00513451480.016
Yeast
negative regulation of cell proliferationGO:00082852960.016
connective tissue developmentGO:00614481790.016
purine ribonucleoside metabolic processGO:00461282410.016
action potentialGO:0001508780.016
organonitrogen compound catabolic processGO:19015652640.016
positive regulation of nucleotide metabolic processGO:00459811140.015
Yeast
purine nucleotide metabolic processGO:00061633020.015
nls bearing protein import into nucleusGO:000660720.015
Fly
maternal process involved in female pregnancyGO:0060135320.015
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.015
rna 3 end processingGO:0031123200.015
spermatid developmentGO:00072861080.015
carbohydrate derivative biosynthetic processGO:19011371830.015
neuron apoptotic processGO:00514021420.015
photoreceptor cell morphogenesisGO:000859430.014
gonad developmentGO:00084061410.014
multi multicellular organism processGO:00447061090.014
positive regulation of bindingGO:0051099490.014
developmental growth involved in morphogenesisGO:00605601380.014
regulation of protein stabilityGO:0031647520.014
positive regulation of dendrite developmentGO:1900006210.014
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.014
regulation of purine nucleotide metabolic processGO:19005421690.014
Yeast
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018410.014
lipid localizationGO:00108761260.013
axonogenesisGO:00074092740.013
protein catabolic processGO:00301632210.013
modification dependent protein catabolic processGO:00199411330.013
regulation of neuron apoptotic processGO:00435231220.013
negative regulation of dna templated transcription terminationGO:006056710.013
lateral inhibitionGO:004633110.013
striated muscle contractionGO:0006941450.013
regulation of protein bindingGO:0043393600.013
viral gene expressionGO:001908030.013
attachment of spindle microtubules to kinetochoreGO:000860840.013
positive regulation of cellular component biogenesisGO:0044089940.013
engulfment of apoptotic cellGO:004365230.013
positive regulation of nfat protein import into nucleusGO:005153310.013
Fly
regulation of cell growthGO:0001558910.012
somatic diversification of immunoglobulinsGO:0016445430.012
positive regulation of transcription initiation from rna polymerase ii promoterGO:006026150.012
sister chromatid segregationGO:0000819200.012
transmission of nerve impulseGO:0019226760.012
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.012
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046610.012
interspecies interaction between organismsGO:0044419830.012
histone lysine methylationGO:0034968500.012
regulation of hydrolase activityGO:00513362460.012
Yeast
sensory organ morphogenesisGO:00905962420.012
positive regulation of leukocyte mediated immunityGO:0002705700.012
purine ribonucleoside triphosphate metabolic processGO:00092052200.012
muscle cell differentiationGO:00426922610.012
locomotory behaviorGO:00076261950.012
establishment or maintenance of cytoskeleton polarityGO:003095220.012
regulation of cellular catabolic processGO:00313292420.012
Yeast
regulation of protein export from nucleusGO:0046825110.012
cellular component assembly involved in morphogenesisGO:00109271390.011
negative regulation of cellular component organizationGO:00511291940.011
intracellular receptor signaling pathwayGO:0030522740.011
regulation of wnt signaling pathwayGO:00301111230.011
positive regulation of cell cycle processGO:0090068610.011
epidermis developmentGO:00085441870.011
maternal placenta developmentGO:0001893200.011
hindbrain developmentGO:00309021280.011
establishment of organelle localizationGO:00516561220.011
cellular response to dna damage stimulusGO:00069742070.011
negative regulation of viral genome replicationGO:0045071100.011
negative regulation of multi organism processGO:0043901680.011
positive regulation of protein modification processGO:00314012990.011
embryonic organ morphogenesisGO:00485622760.011
regulation of cell migrationGO:00303342190.011
small gtpase mediated signal transductionGO:0007264970.011
positive regulation of organelle organizationGO:00106381280.011
regulation of lymphocyte mediated immunityGO:0002706840.011
compound eye developmentGO:004874910.011
regulation of ubiquitin protein ligase activity involved in mitotic cell cycleGO:005143910.011
blood vessel morphogenesisGO:00485142850.011
cofactor metabolic processGO:0051186800.011
anatomical structure homeostasisGO:00602491450.011
intracellular steroid hormone receptor signaling pathwayGO:0030518290.011
regulation of g1 s transition of mitotic cell cycleGO:2000045350.011
regulation of transcription factor import into nucleusGO:0042990240.011
Fly
multicellular organism growthGO:00352641610.011
endocytosisGO:00068971680.011
negative regulation of cell developmentGO:00107211690.011
prostate glandular acinus developmentGO:0060525120.011
cellular response to peptide hormone stimulusGO:0071375920.011
positive regulation of rna splicingGO:0033120120.010
cellular response to oxidative stressGO:0034599760.010
skeletal system developmentGO:00015013560.010
positive regulation of cell activationGO:00508671580.010
symbiosis encompassing mutualism through parasitismGO:0044403830.010
protein ubiquitinationGO:00165671710.010
positive regulation of translationGO:0045727190.010
guanosine containing compound metabolic processGO:19010681440.010
rna catabolic processGO:0006401290.010
regulation of cytokine productionGO:00018172660.010
nucleoside phosphate biosynthetic processGO:1901293790.010
dna templated transcription terminationGO:000635340.010
positive regulation of cellular catabolic processGO:00313311480.010
Yeast
tissue homeostasisGO:00018941150.010
cellular ketone metabolic processGO:0042180840.010
organophosphate biosynthetic processGO:00904071220.010
Yeast
embryonic skeletal system developmentGO:00487061200.010

Kpnb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.038
disease of anatomical entityDOID:700.038
central nervous system diseaseDOID:33100.030
disease of cellular proliferationDOID:1456600.021
intestinal cancerDOID:1015500.021
gastrointestinal system cancerDOID:311900.021
cancerDOID:16200.021
colon cancerDOID:21900.021
organ system cancerDOID:005068600.021
large intestine cancerDOID:567200.021
colorectal cancerDOID:925600.021
neurodegenerative diseaseDOID:128900.014