IMP: Integrative Multi-species Prediction

Mus musculus

14 known processes

Ldha

lactate dehydrogenase A

(Aliases: Ldhm,Ldh1,l7R2)

Entrez: 16828
Ensembl: ENSMUSG00000063229
UniProtKB: Q564E2
UniProtKB: G5E8N5
UniProtKB: P06151

Process Predictions
Disease Predictions

Ldha biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
carbohydrate catabolic process	GO:0016052	32	1.000
glycolytic process	GO:0006096	20	0.999
pyruvate metabolic process	GO:0006090	28	0.997	Mouse
hexose catabolic process	GO:0019320	3	0.993
cellular aldehyde metabolic process	GO:0006081	12	0.939
generation of precursor metabolites and energy	GO:0006091	103	0.913
myosin filament organization	GO:0031033	3	0.910
carbohydrate metabolic process	GO:0005975	230	0.862
hexose metabolic process	GO:0019318	98	0.860
carbohydrate phosphorylation	GO:0046835	15	0.824
pentose phosphate shunt	GO:0006098	2	0.817
monocarboxylic acid metabolic process	GO:0032787	191	0.799	Mouse
monosaccharide metabolic process	GO:0005996	106	0.793
nadph regeneration	GO:0006740	2	0.745
cellular component assembly involved in morphogenesis	GO:0010927	139	0.661
ribose phosphate biosynthetic process	GO:0046390	59	0.525	Mouse
purine nucleotide biosynthetic process	GO:0006164	65	0.477	Mouse
muscle cell development	GO:0055001	133	0.466
cellular protein complex assembly	GO:0043623	116	0.465
striated muscle myosin thick filament assembly	GO:0071688	1	0.451
carbohydrate derivative biosynthetic process	GO:1901137	183	0.432	Mouse
glucose metabolic process	GO:0006006	92	0.420
oxidation reduction process	GO:0055114	342	0.379
nitrogen compound transport	GO:0071705	271	0.322
myosin filament assembly	GO:0031034	2	0.319
regulation of translation	GO:0006417	71	0.303
nucleoside metabolic process	GO:0009116	246	0.283	Mouse
ribonucleoside biosynthetic process	GO:0042455	21	0.261	Mouse
atp metabolic process	GO:0046034	75	0.259	Mouse
carbohydrate biosynthetic process	GO:0016051	74	0.215
purine nucleoside biosynthetic process	GO:0042451	19	0.192	Mouse
myotube differentiation	GO:0014902	105	0.189
transmembrane transport	GO:0055085	412	0.181
negative regulation of cellular protein metabolic process	GO:0032269	247	0.180
cellular homeostasis	GO:0019725	240	0.180
monosaccharide biosynthetic process	GO:0046364	44	0.143
purine nucleoside monophosphate metabolic process	GO:0009126	81	0.143	Mouse
response to decreased oxygen levels	GO:0036293	59	0.142	Zebrafish
purine nucleoside monophosphate biosynthetic process	GO:0009127	9	0.142	Mouse
glucose homeostasis	GO:0042593	128	0.140
nucleoside phosphate biosynthetic process	GO:1901293	79	0.138	Mouse
hexose biosynthetic process	GO:0019319	39	0.133
regulation of hormone levels	GO:0010817	211	0.129
gluconeogenesis	GO:0006094	39	0.120
sperm motility	GO:0030317	47	0.116	Mouse
ribose phosphate metabolic process	GO:0019693	291	0.116	Mouse
response to organonitrogen compound	GO:0010243	246	0.114
actomyosin structure organization	GO:0031032	56	0.109
cellular amino acid metabolic process	GO:0006520	103	0.109
purine nucleotide metabolic process	GO:0006163	302	0.100	Mouse
regulation of secretion	GO:0051046	274	0.099
development of primary sexual characteristics	GO:0045137	143	0.092
response to nicotine	GO:0035094	6	0.091
cellular amine metabolic process	GO:0044106	44	0.083
muscle cell differentiation	GO:0042692	261	0.080
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.080	Mouse
positive regulation of apoptotic process	GO:0043065	217	0.080
somitogenesis	GO:0001756	69	0.079
nucleoside biosynthetic process	GO:0009163	21	0.078	Mouse
hormone secretion	GO:0046879	128	0.078
nadp metabolic process	GO:0006739	6	0.073
nucleobase containing small molecule metabolic process	GO:0055086	352	0.072	Mouse
purine containing compound metabolic process	GO:0072521	311	0.072	Mouse
regulation of coenzyme metabolic process	GO:0051196	4	0.071
oxidoreduction coenzyme metabolic process	GO:0006733	16	0.070
amine metabolic process	GO:0009308	45	0.069
response to molecule of bacterial origin	GO:0002237	143	0.067
mitotic cell cycle	GO:0000278	195	0.067
positive regulation of cellular amine metabolic process	GO:0033240	5	0.065
gonad development	GO:0008406	141	0.065
response to organic cyclic compound	GO:0014070	198	0.064
insulin secretion	GO:0030073	89	0.061
cellular carbohydrate catabolic process	GO:0044275	15	0.061
fructose 6 phosphate metabolic process	GO:0006002	1	0.061
mitochondrion organization	GO:0007005	134	0.060
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.059
leukocyte proliferation	GO:0070661	172	0.058
alpha amino acid metabolic process	GO:1901605	59	0.058
purine ribonucleoside metabolic process	GO:0046128	241	0.058	Mouse
myofibril assembly	GO:0030239	34	0.056
regulation of cofactor metabolic process	GO:0051193	5	0.055
cellular amide metabolic process	GO:0043603	58	0.054
translation	GO:0006412	93	0.053
mesoderm formation	GO:0001707	62	0.052
nucleotide metabolic process	GO:0009117	332	0.051	Mouse
negative regulation of protein metabolic process	GO:0051248	282	0.051
cell redox homeostasis	GO:0045454	6	0.051
maintenance of location	GO:0051235	89	0.050
cellular response to organonitrogen compound	GO:0071417	145	0.050
regulation of glycolytic process	GO:0006110	10	0.049
positive regulation of peptide secretion	GO:0002793	33	0.048
cation transport	GO:0006812	399	0.048
organophosphate biosynthetic process	GO:0090407	122	0.047	Mouse
cofactor metabolic process	GO:0051186	80	0.045
purine nucleoside triphosphate biosynthetic process	GO:0009145	7	0.045	Mouse
regulation of cell cycle	GO:0051726	281	0.044
inorganic cation transmembrane transport	GO:0098662	207	0.043
response to lipopolysaccharide	GO:0032496	128	0.043
cytoplasmic transport	GO:0016482	234	0.043
response to oxidative stress	GO:0006979	123	0.042
regulation of peptide transport	GO:0090087	91	0.042
organic hydroxy compound biosynthetic process	GO:1901617	77	0.042	Mouse
positive regulation of hormone secretion	GO:0046887	38	0.042
regulation of cellular amino acid metabolic process	GO:0006521	5	0.040
cristae formation	GO:0042407	3	0.040
regulation of cellular ketone metabolic process	GO:0010565	66	0.040
purine ribonucleoside monophosphate metabolic process	GO:0009167	80	0.040	Mouse
cytokine production	GO:0001816	319	0.040
formation of primary germ layer	GO:0001704	77	0.039
organic hydroxy compound metabolic process	GO:1901615	203	0.039	Mouse
regulation of membrane potential	GO:0042391	192	0.039
regulation of phosphatidylcholine biosynthetic process	GO:2001245	2	0.038
multicellular organismal aging	GO:0010259	24	0.038
ion transmembrane transport	GO:0034220	361	0.038
skin development	GO:0043588	220	0.037
apoptotic signaling pathway	GO:0097190	306	0.036
genitalia development	GO:0048806	37	0.036
regulation of cell activation	GO:0050865	289	0.036
regulation of cellular amine metabolic process	GO:0033238	20	0.035
carbohydrate homeostasis	GO:0033500	128	0.034
negative regulation of cell cycle phase transition	GO:1901988	48	0.034
placenta development	GO:0001890	140	0.032
regulation of cellular catabolic process	GO:0031329	242	0.032
pyridine nucleotide biosynthetic process	GO:0019363	4	0.032
protein targeting	GO:0006605	143	0.031
homeostasis of number of cells	GO:0048872	210	0.031
alcohol metabolic process	GO:0006066	116	0.031
glycosyl compound biosynthetic process	GO:1901659	21	0.031	Mouse
negative regulation of peptide secretion	GO:0002792	16	0.030
cation transmembrane transport	GO:0098655	266	0.028
positive regulation of hydrolase activity	GO:0051345	148	0.028
pyridine containing compound metabolic process	GO:0072524	14	0.028
metal ion homeostasis	GO:0055065	189	0.028
peptidyl amino acid modification	GO:0018193	336	0.028
purine ribonucleotide catabolic process	GO:0009154	208	0.028
nucleoside triphosphate metabolic process	GO:0009141	230	0.028	Mouse
cellular lipid metabolic process	GO:0044255	323	0.028
purine ribonucleotide biosynthetic process	GO:0009152	59	0.027	Mouse
energy derivation by oxidation of organic compounds	GO:0015980	77	0.027
lipid localization	GO:0010876	126	0.027
t cell activation	GO:0042110	289	0.027
organonitrogen compound biosynthetic process	GO:1901566	192	0.026	Mouse
cellular carbohydrate metabolic process	GO:0044262	119	0.026
spermatogenesis	GO:0007283	284	0.026
regulation of glucose metabolic process	GO:0010906	60	0.026
purine nucleoside metabolic process	GO:0042278	241	0.026	Mouse
regulation of reactive oxygen species biosynthetic process	GO:1903426	2	0.026
apoptotic mitochondrial changes	GO:0008637	48	0.026
peptidyl proline hydroxylation	GO:0019511	3	0.026
regulation of carbohydrate metabolic process	GO:0006109	75	0.025
nucleoside phosphate metabolic process	GO:0006753	338	0.025	Mouse
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.025	Mouse
lymphocyte proliferation	GO:0046651	164	0.025
protein catabolic process	GO:0030163	221	0.025
positive regulation of cell death	GO:0010942	224	0.025
pigmentation	GO:0043473	71	0.024
ribonucleotide metabolic process	GO:0009259	291	0.024	Mouse
muscle system process	GO:0003012	141	0.024
striated muscle cell development	GO:0055002	125	0.024
muscle cell cellular homeostasis	GO:0046716	12	0.023
mitotic cell cycle checkpoint	GO:0007093	31	0.023
regulation of mitotic cell cycle	GO:0007346	126	0.023
cell type specific apoptotic process	GO:0097285	268	0.023
anatomical structure homeostasis	GO:0060249	145	0.022
epithelial tube morphogenesis	GO:0060562	303	0.022
regulation of lymphocyte activation	GO:0051249	240	0.022
response to heat	GO:0009408	27	0.022
neuron death	GO:0070997	154	0.022
locomotory behavior	GO:0007626	195	0.022
pyridine nucleotide metabolic process	GO:0019362	12	0.021
amide transport	GO:0042886	138	0.021
cation homeostasis	GO:0055080	212	0.021
regulation of secretion by cell	GO:1903530	249	0.021
cellular ketone metabolic process	GO:0042180	84	0.021
regulation of cytokine production	GO:0001817	266	0.021
regulation of hydrolase activity	GO:0051336	246	0.021
regulation of cell cycle phase transition	GO:1901987	77	0.021
cellular modified amino acid metabolic process	GO:0006575	63	0.021
regulation of transferase activity	GO:0051338	263	0.021
cellular response to cytokine stimulus	GO:0071345	189	0.021
regulation of nucleoside metabolic process	GO:0009118	130	0.020
t cell proliferation	GO:0042098	120	0.020
organic acid transport	GO:0015849	101	0.020
cellular ion homeostasis	GO:0006873	165	0.020
somite development	GO:0061053	81	0.020
nucleotide biosynthetic process	GO:0009165	78	0.020	Mouse
axonogenesis	GO:0007409	274	0.020
syncytium formation	GO:0006949	43	0.020
regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity	GO:0031585	2	0.020
organic hydroxy compound transport	GO:0015850	93	0.019
neural tube formation	GO:0001841	108	0.019
regulation of t cell activation	GO:0050863	170	0.019
regulation of protein localization	GO:0032880	231	0.019
regulation of metal ion transport	GO:0010959	106	0.019
positive regulation of insulin secretion	GO:0032024	26	0.019
response to estrogen	GO:0043627	24	0.019
glycerolipid metabolic process	GO:0046486	122	0.019
regulation of intrinsic apoptotic signaling pathway	GO:2001242	61	0.019
intrinsic apoptotic signaling pathway	GO:0097193	132	0.019
segmentation	GO:0035282	93	0.019
g protein coupled receptor signaling pathway	GO:0007186	243	0.019
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	34	0.019
spermatid differentiation	GO:0048515	115	0.018
posttranscriptional regulation of gene expression	GO:0010608	155	0.018
regulation of leukocyte proliferation	GO:0070663	121	0.018
cellular response to dna damage stimulus	GO:0006974	207	0.018
potassium ion transport	GO:0006813	52	0.018
positive regulation of programmed cell death	GO:0043068	218	0.018
purine ribonucleoside monophosphate biosynthetic process	GO:0009168	9	0.018	Mouse
male gamete generation	GO:0048232	285	0.018
epithelial cell development	GO:0002064	159	0.018
ribonucleoside monophosphate biosynthetic process	GO:0009156	9	0.018	Mouse
regulation of protein kinase activity	GO:0045859	232	0.018
negative regulation of cell cycle	GO:0045786	123	0.018
positive regulation of protein modification process	GO:0031401	299	0.017
extracellular matrix organization	GO:0030198	147	0.017
reactive oxygen species biosynthetic process	GO:1903409	8	0.017
inorganic ion transmembrane transport	GO:0098660	234	0.017
developmental maturation	GO:0021700	193	0.017
oxygen homeostasis	GO:0032364	2	0.017
purine ribonucleoside triphosphate biosynthetic process	GO:0009206	6	0.017	Mouse
negative regulation of cell proliferation	GO:0008285	296	0.017
circadian regulation of gene expression	GO:0032922	48	0.017
transition metal ion homeostasis	GO:0055076	54	0.017
b cell activation	GO:0042113	161	0.017
actin cytoskeleton organization	GO:0030036	220	0.017
anion transport	GO:0006820	177	0.017
reactive nitrogen species metabolic process	GO:2001057	0	0.017
ras protein signal transduction	GO:0007265	77	0.017
epidermis development	GO:0008544	187	0.017
response to inorganic substance	GO:0010035	96	0.017
reactive oxygen species metabolic process	GO:0072593	84	0.016
respiratory system development	GO:0060541	190	0.016
ribonucleotide biosynthetic process	GO:0009260	59	0.016	Mouse
phospholipid metabolic process	GO:0006644	87	0.016
learning or memory	GO:0007611	148	0.016
ribonucleoside triphosphate biosynthetic process	GO:0009201	6	0.016	Mouse
rhythmic process	GO:0048511	174	0.016
regulation of phospholipid biosynthetic process	GO:0071071	3	0.016
regulation of mapk cascade	GO:0043408	248	0.016
dna metabolic process	GO:0006259	303	0.016
cellular response to lipid	GO:0071396	145	0.016
regulation of protein serine threonine kinase activity	GO:0071900	157	0.016
organic anion transport	GO:0015711	137	0.016
protein polymerization	GO:0051258	57	0.016
protein modification by small protein conjugation	GO:0032446	187	0.016
ribonucleoside catabolic process	GO:0042454	206	0.016
immune response regulating signaling pathway	GO:0002764	125	0.016
response to acid chemical	GO:0001101	111	0.016
protein ubiquitination	GO:0016567	171	0.016
nicotinamide nucleotide metabolic process	GO:0046496	12	0.016
purine ribonucleotide metabolic process	GO:0009150	290	0.016	Mouse
myeloid cell homeostasis	GO:0002262	114	0.016
regulation of organelle organization	GO:0033043	289	0.016
epithelial cell proliferation	GO:0050673	174	0.016
negative regulation of neuron death	GO:1901215	98	0.015
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.015
regulation of endopeptidase activity	GO:0052548	89	0.015
regulation of defense response	GO:0031347	233	0.015
regulation of cysteine type endopeptidase activity	GO:2000116	65	0.015
pyridine containing compound catabolic process	GO:0072526	4	0.015
carboxylic acid biosynthetic process	GO:0046394	86	0.015	Mouse
regulation of ion transport	GO:0043269	215	0.015
negative regulation of cell cycle process	GO:0010948	69	0.015
nucleoside monophosphate metabolic process	GO:0009123	85	0.015	Mouse
positive regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043280	36	0.015
leukocyte differentiation	GO:0002521	342	0.015
lateral inhibition	GO:0046331	1	0.015
negative regulation of intracellular signal transduction	GO:1902532	167	0.015
4 hydroxyproline metabolic process	GO:0019471	5	0.015
striated muscle contraction	GO:0006941	45	0.015
aromatic compound catabolic process	GO:0019439	286	0.014
fat cell differentiation	GO:0045444	160	0.014
cellular response to hormone stimulus	GO:0032870	150	0.014
negative regulation of cellular amine metabolic process	GO:0033239	1	0.014
carbohydrate derivative catabolic process	GO:1901136	231	0.014
positive regulation of reactive oxygen species metabolic process	GO:2000379	11	0.014
protein oligomerization	GO:0051259	67	0.014
peptide hormone secretion	GO:0030072	109	0.014
second messenger mediated signaling	GO:0019932	73	0.014
regulation of fat cell differentiation	GO:0045598	81	0.014
regionalization	GO:0003002	337	0.014
organelle assembly	GO:0070925	177	0.014
lymphocyte differentiation	GO:0030098	242	0.014
regulation of proteolysis	GO:0030162	164	0.013
response to steroid hormone	GO:0048545	56	0.013
sensory perception	GO:0007600	245	0.013
heterocycle catabolic process	GO:0046700	280	0.013
activation of immune response	GO:0002253	138	0.013
positive regulation of nucleoside metabolic process	GO:0045979	91	0.013
protein processing	GO:0016485	163	0.013
positive regulation of protein phosphorylation	GO:0001934	242	0.013
phosphatidylethanolamine metabolic process	GO:0046337	2	0.013
protein modification by small protein conjugation or removal	GO:0070647	207	0.013
neuron neuron synaptic transmission	GO:0007270	69	0.013
regulation of transmembrane transport	GO:0034762	128	0.013
g2 dna damage checkpoint	GO:0031572	8	0.013
regulation of peptide secretion	GO:0002791	77	0.013
organonitrogen compound catabolic process	GO:1901565	264	0.013
gas homeostasis	GO:0033483	3	0.013
cellular response to acid chemical	GO:0071229	68	0.013
regulation of kinase activity	GO:0043549	249	0.013
immune response activating signal transduction	GO:0002757	116	0.013
monocarboxylic acid biosynthetic process	GO:0072330	61	0.013	Mouse
sulfur compound metabolic process	GO:0006790	100	0.013
forebrain development	GO:0030900	302	0.013
negative regulation of translation	GO:0017148	22	0.013
cellular metal ion homeostasis	GO:0006875	151	0.013
regulation of cellular carbohydrate metabolic process	GO:0010675	75	0.013
nicotinamide nucleotide biosynthetic process	GO:0019359	4	0.013
sensory organ morphogenesis	GO:0090596	242	0.013
monocarboxylic acid transport	GO:0015718	44	0.012
substantia nigra development	GO:0021762	2	0.012	Human
regulation of apoptotic signaling pathway	GO:2001233	197	0.012
positive regulation of growth	GO:0045927	104	0.012
positive regulation of proteolysis	GO:0045862	85	0.012
regulation of cellular response to stress	GO:0080135	159	0.012
regulation of leukocyte differentiation	GO:1902105	159	0.012
innate immune response	GO:0045087	157	0.012
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.012
proteasomal protein catabolic process	GO:0010498	98	0.012
carboxylic acid transport	GO:0046942	100	0.012
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.012
morphogenesis of a branching epithelium	GO:0061138	193	0.012
nuclear transport	GO:0051169	139	0.012
myeloid cell differentiation	GO:0030099	233	0.012
negative regulation of phosphorus metabolic process	GO:0010563	184	0.012
glutamine family amino acid biosynthetic process	GO:0009084	2	0.012
protein maturation	GO:0051604	176	0.012
regulation of neuron apoptotic process	GO:0043523	122	0.012
compound eye development	GO:0048749	1	0.012
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.012
mapk cascade	GO:0000165	281	0.011
negative regulation of mammary gland epithelial cell proliferation	GO:0033600	3	0.011
regulation of receptor activity	GO:0010469	41	0.011
respiratory tube development	GO:0030323	167	0.011
positive regulation of cellular catabolic process	GO:0031331	148	0.011
peptidyl tyrosine modification	GO:0018212	145	0.011
regulation of leukocyte apoptotic process	GO:2000106	56	0.011
small gtpase mediated signal transduction	GO:0007264	97	0.011
dephosphorylation	GO:0016311	129	0.011
localization within membrane	GO:0051668	4	0.011
positive regulation of nucleotide metabolic process	GO:0045981	114	0.011
neuronal action potential	GO:0019228	54	0.011
circadian rhythm	GO:0007623	114	0.011
positive regulation of cysteine type endopeptidase activity	GO:2001056	39	0.011
cellular nitrogen compound catabolic process	GO:0044270	280	0.011
regulation of establishment of protein localization	GO:0070201	181	0.011
negative regulation of mitotic cell cycle phase transition	GO:1901991	45	0.011
positive regulation of cell activation	GO:0050867	158	0.011
small molecule catabolic process	GO:0044282	71	0.011
determination of adult lifespan	GO:0008340	11	0.011
activation of cysteine type endopeptidase activity	GO:0097202	27	0.011
regulation of nucleotide metabolic process	GO:0006140	169	0.011
cellular response to peptide hormone stimulus	GO:0071375	92	0.011
peptide transport	GO:0015833	133	0.011
mesoderm development	GO:0007498	100	0.011
positive regulation of reactive oxygen species biosynthetic process	GO:1903428	2	0.011
cellular response to biotic stimulus	GO:0071216	92	0.011
divalent metal ion transport	GO:0070838	172	0.011
purine containing compound catabolic process	GO:0072523	213	0.011
skeletal system development	GO:0001501	356	0.011
intracellular protein transport	GO:0006886	204	0.011
glycerophospholipid metabolic process	GO:0006650	71	0.011
regulation of interleukin 8 production	GO:0032677	3	0.010
inflammatory response	GO:0006954	244	0.010
positive regulation of transmembrane transport	GO:0034764	29	0.010
cellular response to lipopolysaccharide	GO:0071222	77	0.010
connective tissue development	GO:0061448	179	0.010
response to nutrient levels	GO:0031667	109	0.010
renal system development	GO:0072001	225	0.010
cell adhesion	GO:0007155	329	0.010
gland development	GO:0048732	330	0.010
iron ion homeostasis	GO:0055072	36	0.010
defecation	GO:0030421	1	0.010
cellular response to molecule of bacterial origin	GO:0071219	83	0.010
divalent inorganic cation transport	GO:0072511	178	0.010
regulation of lymphocyte differentiation	GO:0045619	107	0.010
divalent inorganic cation homeostasis	GO:0072507	138	0.010
chromatin organization	GO:0006325	206	0.010
positive regulation of protein kinase activity	GO:0045860	144	0.010

Ldha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.637
carbohydrate metabolism disease	DOID:0050013	0.382
acquired metabolic disease	DOID:0060158	0.382
glucose metabolism disease	DOID:4194	0.382
disease of anatomical entity	DOID:7	0.082
nervous system disease	DOID:863	0.082
immune system disease	DOID:2914	0.062
anemia	DOID:2355	0.047
hematopoietic system disease	DOID:74	0.047
central nervous system disease	DOID:331	0.017
disease of cellular proliferation	DOID:14566	0.014
cancer	DOID:162	0.014
sensory system disease	DOID:0050155	0.012
eye disease	DOID:5614	0.012
eye and adnexa disease	DOID:1492	0.012
neurodegenerative disease	DOID:1289	0.011
organ system cancer	DOID:0050686	0.011
neuropathy	DOID:870	0.011

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