Mus musculus

316 known processes

Lef1

lymphoid enhancer binding factor 1

(Aliases: Lef-1,AI451430,3000002B05)

Lef1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
trachea gland developmentGO:006115331.000
formation of radial glial scaffoldsGO:002194341.000
regionalizationGO:00030023371.000
telencephalon developmentGO:00215371861.000
embryonic organ morphogenesisGO:00485622760.999
Mouse
embryonic appendage morphogenesisGO:00351131260.999
polarity specification of proximal distal axisGO:001008520.998
Worm
genitalia morphogenesisGO:0035112110.998
Mouse
gastrulationGO:00073691160.998
formation of primary germ layerGO:0001704770.998
forebrain generation of neuronsGO:0021872630.996
cell fate commitmentGO:00451652100.996
Mouse Worm
forebrain radial glial cell differentiationGO:002186140.996
limb developmentGO:00601731660.996
diencephalon developmentGO:0021536630.995
Zebrafish Mouse
secretory granule localizationGO:003225230.994
Mouse
forebrain neuroblast divisionGO:002187390.994
cell fate specificationGO:0001708720.993
Worm
hindbrain developmentGO:00309021280.992
bmp signaling pathwayGO:0030509930.992
somatic diversification of t cell receptor genesGO:000256850.992
regulation of asymmetric cell divisionGO:000978640.991
Worm
regulation of stem cell differentiationGO:2000736500.991
Human Mouse
mesoderm formationGO:0001707620.991
regulation of stem cell proliferationGO:0072091780.990
Fly
neuroblast divisionGO:0055057100.990
embryonic genitalia morphogenesisGO:003053840.990
Mouse
appendage morphogenesisGO:00351071490.989
somatic stem cell maintenanceGO:0035019470.989
Mouse
oligodendrocyte developmentGO:0014003200.989
Mouse
mesoderm morphogenesisGO:0048332640.989
dentate gyrus developmentGO:0021542140.989
somitogenesisGO:0001756690.988
embryonic limb morphogenesisGO:00303261260.988
appendage developmentGO:00487361660.987
fibroblast growth factor receptor signaling pathwayGO:0008543460.987
Mouse
mesoderm developmentGO:00074981000.987
digestive system developmentGO:00551232000.987
apoptotic process involved in patterning of blood vesselsGO:190226260.987
morphogenesis of a branching epitheliumGO:00611381930.986
regulation of bmp signaling pathwayGO:0030510600.986
Mouse
glial cell differentiationGO:00100011310.986
odontogenesis of dentin containing toothGO:0042475660.985
defecationGO:003042110.984
Worm
digestive tract developmentGO:00485651900.984
glial cell developmentGO:0021782540.984
Mouse
regulation of transcription from rna polymerase ii promoter mitoticGO:004602110.983
Mouse
mesenchyme morphogenesisGO:0072132320.982
face morphogenesisGO:0060325290.978
oligodendrocyte differentiationGO:0048709530.977
Mouse
stem cell maintenanceGO:00198271300.975
Mouse
limb morphogenesisGO:00351081490.974
alpha beta t cell differentiationGO:0046632690.974
gliogenesisGO:00420631410.973
regulation of transcription during mitosisGO:004589610.973
Mouse
spinal cord developmentGO:0021510810.973
response to growth factorGO:00708481980.972
Mouse
muscle tissue developmentGO:00605373080.972
hippocampus developmentGO:0021766520.971
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.971
pituitary gland developmentGO:0021983380.970
Mouse
canonical wnt signaling pathway involved in negative regulation of apoptotic processGO:004433640.970
Mouse
somatic recombination of t cell receptor gene segmentsGO:000268150.969
chorio allantoic fusionGO:006071080.969
urogenital system developmentGO:00016552610.968
Rat
cd4 positive alpha beta t cell activationGO:0035710450.966
embryonic skeletal system developmentGO:00487061200.966
renal tubule developmentGO:0061326870.965
negative regulation of cellular response to growth factor stimulusGO:0090288460.965
Mouse
radial glial cell differentiationGO:006001960.964
negative regulation of bmp signaling pathwayGO:0030514350.964
Mouse
neural precursor cell proliferationGO:00613511210.964
epithelial to mesenchymal transitionGO:0001837470.963
regulation of cellular ketone metabolic processGO:0010565660.963
Zebrafish Mouse
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoterGO:007236470.963
Mouse
regulation of glial cell differentiationGO:0045685410.960
Mouse
limbic system developmentGO:0021761720.958
neural tube developmentGO:00219151600.954
Mouse
wnt signaling pathwayGO:00160551880.953
mesenchymal cell developmentGO:0014031930.951
t cell receptor v d j recombinationGO:003315350.951
nephron morphogenesisGO:0072028690.950
palate developmentGO:0060021760.950
cell migration in hindbrainGO:0021535160.949
positive regulation of transcription during mitosisGO:004589710.949
Mouse
stem cell developmentGO:00488642190.948
alpha beta t cell differentiation involved in immune responseGO:0002293300.948
regulation of cell fate commitmentGO:0010453190.947
Worm
regulation of cell divisionGO:0051302760.945
Worm
cd4 positive alpha beta t cell differentiationGO:0043367410.943
renal system developmentGO:00720012250.942
Rat
embryonic skeletal system morphogenesisGO:0048704910.937
kidney morphogenesisGO:0060993830.937
axon guidanceGO:00074111410.937
axial mesoderm developmentGO:004831880.934
Mouse
response to fibroblast growth factorGO:0071774470.933
Mouse
morphogenesis of a branching structureGO:00017632030.933
somite developmentGO:0061053810.931
neuron projection guidanceGO:00974851410.930
endodermal cell fate commitmentGO:0001711120.927
fat cell differentiationGO:00454441600.925
Mouse
regulation of organ growthGO:0046620610.924
Mouse
angiogenesisGO:00015252010.923
gland developmentGO:00487323300.923
segmentationGO:0035282930.921
stem cell differentiationGO:00488632680.919
tongue developmentGO:0043586180.918
cellular response to carbohydrate stimulusGO:0071322500.917
Mouse
commitment of neuronal cell to specific neuron type in forebrainGO:002190270.915
t cell differentiationGO:00302171740.913
regulation of epithelial cell proliferationGO:00506781410.912
Mouse
odontogenesisGO:0042476780.911
insulin metabolic processGO:190114230.910
Mouse
acylglycerol biosynthetic processGO:0046463180.907
Mouse
apoptotic process involved in morphogenesisGO:0060561250.903
positive regulation of triglyceride metabolic processGO:009020890.901
Mouse
ear developmentGO:00435832000.901
mesodermal cell fate commitmentGO:0001710170.901
Worm
salivary gland morphogenesisGO:0007435330.897
Fly
planar cell polarity pathway involved in cardiac muscle tissue morphogenesisGO:006135020.897
neuroblast differentiationGO:001401620.897
protein localization to nucleusGO:00345041210.897
Mouse
mesenchyme developmentGO:00604851520.896
epithelial tube morphogenesisGO:00605623030.896
cerebral cortex developmentGO:0021987860.895
wnt signaling pathway involved in forebrain neuroblast divisionGO:002187420.894
ensheathment of neuronsGO:0007272760.894
Mouse
ureteric bud morphogenesisGO:0060675620.894
digestive tract morphogenesisGO:00485461470.893
mesenchymal cell differentiationGO:00487621070.892
regulation of gluconeogenesis by regulation of transcription from rna polymerase ii promoterGO:003594770.887
Mouse
forebrain developmentGO:00309003020.885
regulation of wnt signaling pathwayGO:00301111230.885
trachea submucosa developmentGO:006115230.877
negative regulation of cardiac chamber morphogenesisGO:190122020.876
stem cell proliferationGO:00720891170.875
catenin import into nucleusGO:003541160.874
Mouse
regulation of cell morphogenesis involved in differentiationGO:00107691510.866
Human
cell divisionGO:00513011200.866
multicellular organism growthGO:00352641610.863
Mouse
organ growthGO:00352651170.862
Mouse
posttranscriptional gene silencingGO:0016441100.860
Worm
negative regulation of cell developmentGO:00107211690.854
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.854
Mouse
myelinationGO:0042552740.850
Mouse
regulation of muscle tissue developmentGO:1901861970.850
nephric duct formationGO:007217940.849
regulation of fat cell differentiationGO:0045598810.847
Mouse
face developmentGO:0060324380.846
positive regulation of secondary heart field cardioblast proliferationGO:007251340.845
positive regulation of insulin secretionGO:0032024260.838
Mouse
skeletal system developmentGO:00015013560.837
axial mesoderm morphogenesisGO:004831950.837
Mouse
ear morphogenesisGO:00424711180.836
leukocyte differentiationGO:00025213420.835
mesonephric tubule developmentGO:0072164940.834
axonogenesisGO:00074092740.833
canonical wnt signaling pathwayGO:00600701300.833
Human Zebrafish Mouse
somatic diversification of immune receptorsGO:0002200530.833
embryonic digestive tract morphogenesisGO:0048557170.832
Mouse
development of primary sexual characteristicsGO:00451371430.823
Worm
anatomical structure regressionGO:006003390.821
regulation of canonical wnt signaling pathwayGO:0060828820.821
Human
cellular polysaccharide metabolic processGO:0044264380.819
Mouse
brain morphogenesisGO:0048854320.815
spinal cord dorsal ventral patterningGO:0021513230.814
axon ensheathmentGO:0008366760.809
Mouse
metanephric dct cell differentiationGO:007224030.807
regulation of cell fate specificationGO:0042659100.804
Worm
carbohydrate homeostasisGO:00335001280.803
Mouse
forebrain neuron fate commitmentGO:0021877130.803
embryonic digestive tract developmentGO:0048566270.802
Mouse
nephron developmentGO:00720061090.802
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.800
Mouse
stem cell divisionGO:0017145300.798
triglyceride biosynthetic processGO:0019432170.791
Mouse
mesodermal cell differentiationGO:0048333220.790
Worm
cellular response to hexose stimulusGO:0071331470.788
Mouse
negative regulation of growthGO:0045926990.788
Mouse
generation of precursor metabolites and energyGO:00060911030.784
Mouse
skin developmentGO:00435882200.784
Mouse Rat
regulation of cell cycleGO:00517262810.782
Human
glucose homeostasisGO:00425931280.782
Mouse
macromolecule methylationGO:00434141200.780
central nervous system neuron differentiationGO:00219531620.778
Zebrafish
energy reserve metabolic processGO:0006112390.777
Mouse
kidney developmentGO:00018222130.774
Rat
glycogen metabolic processGO:0005977320.773
Mouse
negative regulation of neuron differentiationGO:00456651010.771
regulation of organ morphogenesisGO:20000271440.771
skeletal muscle organ developmentGO:00605381630.770
Mouse
pallium developmentGO:00215431200.770
regulation of neuron differentiationGO:00456642810.769
cellular response to growth factor stimulusGO:00713631970.765
Mouse
neuronal action potentialGO:0019228540.764
positive regulation of epithelial cell proliferationGO:0050679680.761
Mouse
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesisGO:007203940.761
mammary placode formationGO:006059640.755
epithelial cell morphogenesisGO:0003382410.753
sensory organ morphogenesisGO:00905962420.753
oxidation reduction processGO:00551143420.750
Mouse
gonad developmentGO:00084061410.749
Worm
head morphogenesisGO:0060323340.749
bone mineralizationGO:0030282540.747
Mouse
regulation of cellular response to growth factor stimulusGO:0090287820.746
Mouse
metanephric nephron morphogenesisGO:0072273190.746
regulation of ossificationGO:00302781120.745
regulation of excretionGO:004406250.745
Worm
cochlea morphogenesisGO:0090103220.742
leukocyte proliferationGO:00706611720.740
nephron tubule formationGO:0072079200.740
regulation of myelinationGO:0031641200.737
Mouse
t cell differentiation involved in immune responseGO:0002292300.737
genitalia developmentGO:0048806370.737
Mouse Worm
embryonic epithelial tube formationGO:00018381300.735
chondrocyte differentiationGO:0002062720.734
dna metabolic processGO:00062593030.734
nephron tubule morphogenesisGO:0072078680.731
negative regulation of organ growthGO:0046621170.728
Mouse
rna interferenceGO:001624620.727
Worm
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.727
regulation of nephron tubule epithelial cell differentiationGO:007218290.727
neuroblast proliferationGO:0007405490.727
branching morphogenesis of an epithelial tubeGO:00487541590.725
negative regulation of cell proliferationGO:00082852960.724
skeletal muscle cell differentiationGO:0035914660.721
skeletal system morphogenesisGO:00487052030.720
endodermal cell fate specificationGO:000171440.720
negative regulation of striated muscle tissue developmentGO:0045843180.720
cellular response to interleukin 4GO:0071353210.717
Human
mitotic cell cycle processGO:19030471590.710
Worm
lipid biosynthetic processGO:00086101790.708
Zebrafish Mouse
morphogenesis of embryonic epitheliumGO:00163311590.707
positive regulation of apoptotic processGO:00430652170.705
Mouse
response to transforming growth factor betaGO:0071559880.702
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.697
developmental growth involved in morphogenesisGO:00605601380.696
spinal cord patterningGO:0021511250.693
protein importGO:00170381010.693
Mouse
cytoplasmic transportGO:00164822340.692
Mouse
protein localization to organelleGO:00333651850.688
Mouse
nuclear transportGO:00511691390.688
Mouse
forebrain neuron differentiationGO:0021879520.687
Zebrafish
metanephric nephron tubule formationGO:007228940.686
negative regulation of molecular functionGO:00440922580.684
Human
alpha beta t cell activationGO:0046631910.683
regulation of triglyceride biosynthetic processGO:0010866100.683
Mouse
placenta developmentGO:00018901400.683
embryonic placenta morphogenesisGO:0060669250.681
regulation of cellular amine metabolic processGO:0033238200.680
developmental programmed cell deathGO:0010623410.676
sensory perceptionGO:00076002450.674
renal tubule morphogenesisGO:0061333720.674
negative regulation of wnt signaling pathwayGO:0030178730.673
Human
bone morphogenesisGO:0060349780.672
axis elongation involved in somitogenesisGO:009024540.672
positive regulation of programmed cell deathGO:00430682180.671
Mouse
midbrain hindbrain boundary developmentGO:003091790.671
v d j recombinationGO:0033151140.670
cerebral cortex neuron differentiationGO:0021895190.670
muscle cell fate specificationGO:004269410.668
microtubule based processGO:00070172360.668
Worm
epithelial cell proliferationGO:00506731740.667
Mouse
labyrinthine layer developmentGO:0060711490.665
ureteric bud developmentGO:0001657940.662
labyrinthine layer morphogenesisGO:0060713210.661
nucleocytoplasmic transportGO:00069131390.652
Mouse
cardiac right atrium morphogenesisGO:000321330.650
t cell activationGO:00421102890.650
peptide secretionGO:00027901140.648
Mouse
endoderm formationGO:0001706200.641
planar cell polarity pathway involved in pericardium morphogenesisGO:006135420.638
positive regulation of cell deathGO:00109422240.638
Mouse
mesonephric tubule morphogenesisGO:0072171630.629
regulation of triglyceride metabolic processGO:0090207170.626
Mouse
heart formationGO:0060914160.625
negative regulation of protein metabolic processGO:00512482820.622
Human
neural tube formationGO:00018411080.621
regulation of membrane potentialGO:00423911920.618
regulation of oligodendrocyte differentiationGO:0048713230.617
Mouse
negative regulation of muscle tissue developmentGO:1901862200.617
planar cell polarity pathway involved in cardiac right atrium morphogenesisGO:006134920.616
blood vessel morphogenesisGO:00485142850.614
sprouting angiogenesisGO:0002040260.614
neuron projection extensionGO:1990138640.613
renal vesicle inductionGO:007203430.612
striated muscle tissue developmentGO:00147062930.611
bone developmentGO:00603481200.611
mesonephric tubule formationGO:0072172110.608
regulation of chromosome organizationGO:0033044830.607
neuronal stem cell divisionGO:0036445100.607
regulation of leukocyte differentiationGO:19021051590.606
Human
epidermis developmentGO:00085441870.602
forebrain cell migrationGO:0021885580.599
mesonephros developmentGO:0001823970.599
epithelial tube formationGO:00721751300.594
posttranscriptional gene silencing by rnaGO:0035194100.590
Worm
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiationGO:000325730.588
regulation of neuron projection developmentGO:00109751690.588
pharynx developmentGO:006046510.587
Worm
epithelial cell developmentGO:00020641590.586
homeostasis of number of cellsGO:00488722100.581
Zebrafish
response to monosaccharideGO:0034284670.580
Mouse
regulation of mesenchymal cell apoptotic processGO:2001053140.579
cell proliferation in hindbrainGO:0021534100.575
cellular ketone metabolic processGO:0042180840.572
Zebrafish Mouse
body morphogenesisGO:0010171450.569
ossificationGO:00015032160.567
Human Mouse
camera type eye developmentGO:00430102660.567
positive regulation of growthGO:00459271040.565
Human
epithelial to mesenchymal transition involved in endocardial cushion formationGO:0003198100.564
methylationGO:00322591340.561
lung inductionGO:006049230.557
single organism cell adhesionGO:00986021560.550
morphogenesis of a polarized epitheliumGO:0001738370.549
cell proliferation in forebrainGO:0021846300.549
leukocyte activation involved in immune responseGO:00023661260.548
metanephros morphogenesisGO:0003338240.546
trachea cartilage morphogenesisGO:006053540.546
inner ear morphogenesisGO:00424721010.545
glucan metabolic processGO:0044042320.544
Mouse
histone methylationGO:0016571710.544
alpha beta t cell activation involved in immune responseGO:0002287310.544
lymphocyte proliferationGO:00466511640.543
hair follicle developmentGO:0001942850.538
organelle localizationGO:00516401790.537
Mouse
regulation of apoptotic signaling pathwayGO:20012331970.537
regulation of epithelial cell differentiation involved in kidney developmentGO:2000696100.533
endodermal cell fate determinationGO:000749320.529
response to extracellular stimulusGO:00099911270.527
Mouse
regulation of heart growthGO:0060420310.523
multicellular organismal signalingGO:0035637910.522
lymphocyte differentiationGO:00300982420.521
motor neuron migrationGO:009747540.521
embryonic placenta developmentGO:0001892980.521
epithelial cell differentiation involved in kidney developmentGO:0035850230.516
positive regulation of cellular amino acid metabolic processGO:004576430.516
muscle cell differentiationGO:00426922610.516
Zebrafish Mouse
positive regulation of branching involved in ureteric bud morphogenesisGO:0090190180.514
vagus nerve developmentGO:002156430.512
rostrocaudal neural tube patterningGO:0021903120.510
regulation of cellular amino acid metabolic processGO:000652150.509
peptide transportGO:00158331330.508
Mouse
intracellular protein transportGO:00068862040.506
Mouse
olfactory lobe developmentGO:0021988320.502
regulation of epithelial to mesenchymal transitionGO:0010717220.500
Human
branching involved in ureteric bud morphogenesisGO:0001658560.499
cell type specific apoptotic processGO:00972852680.499
Human
apoptotic signaling pathwayGO:00971903060.497
forebrain regionalizationGO:0021871250.497
lung field specificationGO:006042430.496
somatic stem cell divisionGO:0048103190.496
cellular response to cytokine stimulusGO:00713451890.494
Human
telencephalon cell migrationGO:0022029550.494
mesenchymal cell apoptotic processGO:0097152140.490
b cell activationGO:00421131610.487
retina development in camera type eyeGO:00600411190.486
mesenchymal cell proliferationGO:0010463440.484
negative regulation of neuron projection developmentGO:0010977500.482
neuron fate specificationGO:0048665300.482
hindbrain morphogenesisGO:0021575460.481
neural tube closureGO:0001843900.481
positive regulation of hormone secretionGO:0046887380.479
Mouse
metanephric tubule morphogenesisGO:007217390.479
sinoatrial node cell differentiationGO:006092130.479
positive regulation of apoptotic signaling pathwayGO:2001235950.478
developmental cell growthGO:0048588840.476
regulation of cardiac chamber formationGO:190121010.473
amide transportGO:00428861380.472
Mouse
midbrain hindbrain boundary morphogenesisGO:002155540.468
myoblast differentiationGO:0045445520.463
Mouse
cell differentiation involved in kidney developmentGO:0061005330.460
regulation of hormone levelsGO:00108172110.460
Zebrafish Mouse
cranial nerve morphogenesisGO:0021602260.459
negative regulation of canonical wnt signaling pathwayGO:0090090510.459
Human
blastocyst developmentGO:0001824800.454
mesenchymal stem cell maintenance involved in metanephric nephron morphogenesisGO:007230930.453
negative regulation of osteoblast differentiationGO:0045668300.451
chondrocyte developmentGO:0002063240.449
connective tissue developmentGO:00614481790.449
regulation of cardiac chamber morphogenesisGO:190121920.447
heart field specificationGO:000312860.447
regulation of skeletal muscle fiber differentiationGO:190280930.444
regulation of cardiac muscle tissue growthGO:0055021260.441
tube formationGO:00351481400.439
positive regulation of triglyceride biosynthetic processGO:001086760.437
Mouse
regulation of tongue muscle cell differentiationGO:200103520.435
positive regulation of transcription from rna polymerase ii promoter involved in heart developmentGO:190122840.430
visceral motor neuron differentiationGO:002152430.429
male gamete generationGO:00482322850.426
specification of organ identityGO:0010092300.426
regulation of bindingGO:00510981110.419
Human
hindgut morphogenesisGO:000744270.417
Mouse
auditory receptor cell fate determinationGO:004266830.416
vesicle localizationGO:0051648860.416
Mouse
histone lysine methylationGO:0034968500.414
olfactory bulb developmentGO:0021772300.414
thymus developmentGO:0048538410.410
establishment of protein localization to organelleGO:00725941180.408
Mouse
regulation of myeloid cell differentiationGO:0045637960.408
Human
respiratory tube developmentGO:00303231670.407
respiratory system developmentGO:00605411900.406
t helper 1 cell differentiationGO:0045063130.406
regulation of histone methylationGO:0031060300.405
positive regulation of mesenchymal cell proliferationGO:0002053330.405
nephron epithelium morphogenesisGO:0072088680.404
regulation of organelle organizationGO:00330432890.404
mesonephric epithelium developmentGO:0072163940.403
primary neural tube formationGO:0014020950.403
cellular lipid metabolic processGO:00442553230.402
Zebrafish Mouse
mitotic cell cycleGO:00002781950.401
Worm
cell migration involved in gastrulationGO:0042074130.401
negative regulation of photoreceptor cell differentiationGO:004653340.398
insulin secretionGO:0030073890.396
Mouse
metanephric nephron tubule developmentGO:0072234160.396
insulin secretion involved in cellular response to glucose stimulusGO:0035773360.395
Mouse
regulation of neural precursor cell proliferationGO:2000177700.394
kidney rudiment formationGO:007200330.391
negative regulation of canonical wnt signaling pathway involved in neural plate anterior posterior pattern formationGO:006082910.391
germ cell developmentGO:00072811850.390
protein targetingGO:00066051430.390
Mouse
positive regulation of cell developmentGO:00107202370.386
Human Zebrafish
nephric duct morphogenesisGO:007217870.386
mesenchymal cell apoptotic process involved in nephron morphogenesisGO:190114540.385
acylglycerol metabolic processGO:0006639550.384
Mouse
embryonic forelimb morphogenesisGO:0035115320.384
lymphocyte activation involved in immune responseGO:0002285930.383
cellular chemical homeostasisGO:00550822150.382
Mouse
negative regulation of protein modification processGO:00314001630.381
midbrain developmentGO:0030901350.381
metencephalon developmentGO:0022037890.380
nephron tubule developmentGO:0072080840.379
regulation of transcription involved in primary germ layer cell fate commitmentGO:006079620.376
autonomic nervous system developmentGO:0048483430.373
mesodermal to mesenchymal transition involved in gastrulationGO:006080910.371
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesisGO:007204040.369
energy derivation by oxidation of organic compoundsGO:0015980770.369
Mouse
regulation of cardiac cell fate specificationGO:200004310.368
embryonic skeletal joint morphogenesisGO:0060272110.367
cellular amine metabolic processGO:0044106440.365
cardiac ventricle morphogenesisGO:0003208500.364
activation of meiosisGO:009042740.363
cranial nerve developmentGO:0021545410.362
regulation of mesenchymal cell apoptotic process involved in metanephros developmentGO:190021140.359
polysaccharide metabolic processGO:0005976390.356
Mouse
regulation of mesenchymal cell proliferationGO:0010464370.356
osteoblast developmentGO:0002076170.355
t cell differentiation in thymusGO:0033077770.351
nephron tubule epithelial cell differentiationGO:0072160110.348
striated muscle cell developmentGO:00550021250.346
Zebrafish
cardiac septum developmentGO:0003279590.346
glycerolipid biosynthetic processGO:0045017500.344
Mouse
negative regulation of cellular protein metabolic processGO:00322692470.344
Human
positive regulation of epithelial to mesenchymal transitionGO:0010718130.343
Human
cartilage developmentGO:00512161400.342
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.339
metanephros developmentGO:0001656790.337
male sex differentiationGO:00466611090.336
regulation of branching involved in ureteric bud morphogenesisGO:0090189220.336
enamel mineralizationGO:007016670.335
mapk cascadeGO:00001652810.333
trophectodermal cell differentiationGO:0001829210.332
regulation of histone h3 k9 methylationGO:005157080.332
blastocyst formationGO:0001825330.332
spermatogenesisGO:00072832840.330
neuron migrationGO:00017641220.329
regulation of chondrocyte differentiationGO:0032330330.328
positive regulation of stem cell proliferationGO:2000648590.328
erythrocyte differentiationGO:0030218880.328
cerebral cortex cell migrationGO:0021795440.328
positive regulation of t cell activationGO:00508701010.327
cell fate commitment involved in formation of primary germ layerGO:0060795260.326
Worm
posttranscriptional regulation of gene expressionGO:00106081550.324
Worm
canonical wnt signaling pathway involved in regulation of cell proliferationGO:004434030.323
wnt signaling pathway planar cell polarity pathwayGO:0060071270.322
motor neuron axon guidanceGO:0008045260.322
apoptotic process involved in developmentGO:1902742280.320
eye photoreceptor cell differentiationGO:0001754410.320
negative regulation of nervous system developmentGO:00519611560.319
positive regulation of nervous system developmentGO:00519622210.318
Zebrafish
nuclear divisionGO:00002801580.317
cardiac muscle tissue developmentGO:00487381300.316
cardiac endothelial cell differentiationGO:000334840.316
cardiac epithelial to mesenchymal transitionGO:0060317180.315
cardiac cell fate specificationGO:006091220.315
cardiac septum morphogenesisGO:0060411460.314
multicellular organismal homeostasisGO:00488711640.314
Zebrafish
myeloid cell homeostasisGO:00022621140.313
negative regulation of stem cell maintenanceGO:190245540.313
monosaccharide biosynthetic processGO:0046364440.310
Mouse
thyroid stimulating hormone secreting cell differentiationGO:006012940.309
cerebellum developmentGO:0021549770.307
cerebral cortex radially oriented cell migrationGO:0021799310.305
negative regulation of keratinocyte differentiationGO:004561740.305
positive regulation of epithelial cell proliferation involved in lung morphogenesisGO:006050130.305
regulation of cartilage developmentGO:0061035440.305
planar cell polarity pathway involved in outflow tract morphogenesisGO:006134720.300
positive regulation of mesonephros developmentGO:0061213200.300
somatotropin secreting cell differentiationGO:006012640.300
positive regulation of mesoderm developmentGO:200038220.300

Lef1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org