Mus musculus

346 known processes

Lep

leptin

(Aliases: obese,ob)

Lep biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of fatty acid oxidationGO:0046320101.000
cellular response to peptideGO:1901653921.000
cellular lipid catabolic processGO:0044242521.000
neuropeptide signaling pathwayGO:0007218191.000
monosaccharide metabolic processGO:00059961061.000
regulation of fatty acid metabolic processGO:0019217281.000
regulation of triglyceride metabolic processGO:0090207171.000
acylglycerol metabolic processGO:0006639550.999
regulation of nitrogen cycle metabolic processGO:190331410.999
hexose metabolic processGO:0019318980.999
response to growth factorGO:00708481980.999
positive regulation of lipid catabolic processGO:005099660.998
response to peptide hormoneGO:00434341270.998
regulation of carbohydrate biosynthetic processGO:0043255400.998
cellular response to insulin stimulusGO:0032869780.998
response to testosteroneGO:003357430.998
positive regulation of fatty acid oxidationGO:004632140.998
acylglycerol catabolic processGO:0046464110.998
sequestering of triglycerideGO:003073060.997
regulation of insulin receptor signaling pathwayGO:0046626210.996
cellular response to growth factor stimulusGO:00713631970.995
triglyceride metabolic processGO:0006641510.995
cellular carbohydrate metabolic processGO:00442621190.995
negative regulation of lipid catabolic processGO:005099560.995
cellular lipid metabolic processGO:00442553230.994
rhythmic processGO:00485111740.994
positive regulation of cyclic nucleotide biosynthetic processGO:0030804240.994
drug metabolic processGO:001714440.994
neutral lipid metabolic processGO:0006638570.994
regulation of carbohydrate metabolic processGO:0006109750.994
regulation of cellular ketone metabolic processGO:0010565660.994
gland developmentGO:00487323300.993
apoptotic process involved in mammary gland involutionGO:006005740.993
gluconeogenesisGO:0006094390.992
positive regulation of apoptotic process involved in mammary gland involutionGO:006005840.990
adenylate cyclase activating g protein coupled receptor signaling pathwayGO:0007189300.990
positive regulation of nucleotide biosynthetic processGO:0030810260.989
organic acid catabolic processGO:0016054510.989
response to nutrient levelsGO:00316671090.988
response to bile acidGO:190341210.988
lipid catabolic processGO:0016042690.987
response to organonitrogen compoundGO:00102432460.985
alpha amino acid metabolic processGO:1901605590.985
response to corticosteroidGO:0031960200.983
regulation of glutamine family amino acid metabolic processGO:000082010.981
response to peptideGO:19016521360.981
glucose metabolic processGO:0006006920.981
fatty acid metabolic processGO:00066311210.980
glycerolipid metabolic processGO:00464861220.977
regulation of gluconeogenesisGO:0006111300.977
epithelial tube morphogenesisGO:00605623030.975
carbohydrate metabolic processGO:00059752300.972
negative regulation of lipid metabolic processGO:0045833300.970
negative regulation of peptide hormone secretionGO:0090278160.970
regulation of lipid catabolic processGO:0050994150.970
positive regulation of triglyceride metabolic processGO:009020890.970
fatty acid beta oxidationGO:0006635160.970
regulation of cellular carbohydrate metabolic processGO:0010675750.966
response to glucocorticoidGO:0051384200.964
negative regulation of gluconeogenesisGO:004572190.964
small molecule catabolic processGO:0044282710.963
triglyceride catabolic processGO:001943390.961
regulation of glucose metabolic processGO:0010906600.961
cellular response to peptide hormone stimulusGO:0071375920.960
fatty acid oxidationGO:0019395280.960
regulation of hormone secretionGO:0046883880.959
response to insulinGO:00328681000.958
cellular amino acid metabolic processGO:00065201030.958
regulation of cellular amine metabolic processGO:0033238200.956
response to organic cyclic compoundGO:00140701980.956
monocarboxylic acid catabolic processGO:0072329270.954
nitric oxide mediated signal transductionGO:000726340.952
regulation of peptide secretionGO:0002791770.951
response to alcoholGO:0097305480.949
positive regulation of apoptotic processGO:00430652170.948
digestionGO:0007586400.942
ammonia assimilation cycleGO:001967620.942
fatty acid catabolic processGO:0009062250.940
cellular response to transforming growth factor beta stimulusGO:0071560880.940
positive regulation of lipid metabolic processGO:0045834400.939
white fat cell differentiationGO:0050872150.939
regulation of feeding behaviorGO:006025930.936
cellular response to hormone stimulusGO:00328701500.932
regulation of glutamate metabolic processGO:200021110.932
monosaccharide biosynthetic processGO:0046364440.931
brown fat cell differentiationGO:0050873360.931
positive regulation of insulin receptor signaling pathwayGO:004662840.928
glucose homeostasisGO:00425931280.927
connective tissue developmentGO:00614481790.924
regulation of the force of heart contraction by chemical signalGO:000305750.919
organic hydroxy compound metabolic processGO:19016152030.919
regulation of androgen receptor signaling pathwayGO:006076530.919
mammary gland duct morphogenesisGO:0060603380.918
cellular ketone metabolic processGO:0042180840.916
regulation of urea metabolic processGO:003425510.915
negative regulation of hormone secretionGO:0046888200.909
regulation of vitamin d biosynthetic processGO:006055610.908
epithelial cell proliferationGO:00506731740.907
regulation of cellular catabolic processGO:00313292420.906
cyclic purine nucleotide metabolic processGO:0052652430.905
regulation of cellular amino acid metabolic processGO:000652150.904
carbohydrate biosynthetic processGO:0016051740.898
creatinine metabolic processGO:004644930.897
collagen biosynthetic processGO:003296470.897
neutral lipid catabolic processGO:0046461110.897
response to transforming growth factor betaGO:0071559880.896
positive regulation of lipid storageGO:0010884100.893
regulation of blood pressureGO:0008217930.890
g protein coupled receptor signaling pathwayGO:00071862430.889
drug catabolic processGO:004273720.887
tertiary branching involved in mammary gland duct morphogenesisGO:006074830.886
multicellular organism growthGO:00352641610.886
glutamine family amino acid metabolic processGO:0009064150.885
glutamate metabolic processGO:000653690.885
negative regulation of androgen receptor signaling pathwayGO:006076630.884
succinate metabolic processGO:000610540.877
g protein coupled receptor internalizationGO:000203130.875
regulation of chromatin modificationGO:1903308570.875
regulation of ammonia assimilation cycleGO:200124810.869
regulation of secretion by cellGO:19035302490.867
circadian rhythmGO:00076231140.867
steroid metabolic processGO:00082021190.865
morphogenesis of a branching structureGO:00017632030.865
regulation of camp metabolic processGO:0030814300.865
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.859
regulation of mast cell differentiationGO:006037530.858
positive regulation of programmed cell deathGO:00430682180.856
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200260.855
regulation of response to foodGO:0032095100.855
cell adhesionGO:00071553290.843
ovulation from ovarian follicleGO:000154290.842
positive regulation of fatty acid metabolic processGO:004592380.842
vasoconstrictionGO:0042310270.836
dna metabolic processGO:00062593030.831
regulation of lipid storageGO:0010883200.831
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188540.827
insulin receptor signaling pathwayGO:0008286490.819
keratinocyte migrationGO:005154630.816
peptide secretionGO:00027901140.799
exogenous drug catabolic processGO:004273810.798
regulation of fatty acid beta oxidationGO:003199810.798
regulation of peptide transportGO:0090087910.796
positive regulation of mapk cascadeGO:00434101700.794
cellular chemical homeostasisGO:00550822150.793
multicellular organismal homeostasisGO:00488711640.792
cellular calcium ion homeostasisGO:00068741190.790
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.785
cellular response to cytokine stimulusGO:00713451890.783
negative regulation of cellular carbohydrate metabolic processGO:0010677190.783
amide transportGO:00428861380.782
regulation of organelle organizationGO:00330432890.777
developmental maturationGO:00217001930.776
peptide transportGO:00158331330.770
positive regulation of triglyceride catabolic processGO:001089830.770
circulatory system processGO:00030131970.770
response to corticosteroneGO:005141210.767
carbohydrate homeostasisGO:00335001280.765
lactationGO:0007595250.764
internal protein amino acid acetylationGO:0006475420.761
lipid localizationGO:00108761260.761
long chain fatty acid transportGO:0015909150.760
chromatin modificationGO:00165681870.758
lipid transportGO:0006869980.758
dicarboxylic acid metabolic processGO:0043648180.757
associative learningGO:0008306610.755
positive regulation of carbohydrate metabolic processGO:0045913300.753
multicellular organismal response to stressGO:0033555620.752
regulation of lipid metabolic processGO:00192161180.749
glycerolipid catabolic processGO:0046503160.745
amine metabolic processGO:0009308450.745
synaptic transmissionGO:00072683290.743
forebrain developmentGO:00309003020.742
peptidyl amino acid modificationGO:00181933360.740
cellular response to prostaglandin stimulusGO:007137920.738
cellular amine metabolic processGO:0044106440.735
cartilage developmentGO:00512161400.733
positive regulation of secretionGO:00510471300.733
mammary gland lobule developmentGO:0061377220.733
negative regulation of triglyceride metabolic processGO:009020940.729
response to extracellular stimulusGO:00099911270.729
branching involved in mammary gland duct morphogenesisGO:0060444270.728
positive regulation of inositol phosphate biosynthetic processGO:006073220.726
negative regulation of insulin secretionGO:0046676140.726
regulation of circadian rhythmGO:0042752580.720
ribose phosphate biosynthetic processGO:0046390590.719
positive regulation of cellular amine metabolic processGO:003324050.716
transforming growth factor beta receptor signaling pathwayGO:0007179710.711
regulation of cell migrationGO:00303342190.710
positive regulation of cellular amino acid metabolic processGO:004576430.706
hormone secretionGO:00468791280.706
negative regulation of peptide secretionGO:0002792160.704
cognitionGO:00508901490.703
positive regulation of peptide secretionGO:0002793330.697
regulation of leukocyte differentiationGO:19021051590.695
purine nucleotide biosynthetic processGO:0006164650.692
regulation of peptide hormone secretionGO:0090276750.692
ossificationGO:00015032160.690
positive regulation of chromosome organizationGO:2001252330.689
cholesterol storageGO:001087840.673
divalent metal ion transportGO:00708381720.672
regulation of reactive oxygen species biosynthetic processGO:190342620.671
intracellular receptor signaling pathwayGO:0030522740.666
long term synaptic potentiationGO:0060291250.658
positive regulation of apoptotic process involved in morphogenesisGO:190233940.653
insulin secretionGO:0030073890.650
response to ketoneGO:1901654150.649
mammary gland epithelium developmentGO:0061180650.647
positive regulation of camp metabolic processGO:0030816190.646
regulation of sequestering of triglycerideGO:001088960.642
internal peptidyl lysine acetylationGO:0018393420.637
hormone metabolic processGO:0042445860.636
regulation of epithelial cell proliferationGO:00506781410.635
positive regulation of glucose metabolic processGO:0010907210.635
peptide hormone secretionGO:00300721090.626
divalent inorganic cation homeostasisGO:00725071380.617
cellular response to prostaglandin e stimulusGO:007138010.616
catecholamine metabolic processGO:0006584300.615
regulation of system processGO:00440572000.610
response to steroid hormoneGO:0048545560.607
positive regulation of camp mediated signalingGO:004395030.602
regulation of hormone levelsGO:00108172110.601
calcium ion transportGO:00068161590.600
developmental programmed cell deathGO:0010623410.598
response to increased oxygen levelsGO:003629620.596
regulation of serotonin uptakeGO:005161120.595
regulation of histone acetylationGO:0035065190.593
regulation of nucleotide biosynthetic processGO:0030808340.591
positive regulation of chromatin modificationGO:1903310280.589
cellular response to vitaminGO:007129520.586
oxidation reduction processGO:00551143420.580
response to dexamethasoneGO:007154880.579
odontogenesisGO:0042476780.579
cellular response to organonitrogen compoundGO:00714171450.576
defense response to other organismGO:00985421970.575
hexose biosynthetic processGO:0019319390.573
regulation of metal ion transportGO:00109591060.573
regulation of the force of heart contractionGO:0002026170.567
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.566
positive regulation of cellular catabolic processGO:00313311480.565
response to foodGO:0032094170.564
asymmetric stem cell divisionGO:009872230.564
cellular response to bile acidGO:190341310.561
regulation of triglyceride catabolic processGO:001089650.560
negative regulation of interferon gamma mediated signaling pathwayGO:006033610.559
positive regulation of glial cell proliferationGO:006025240.559
vitamin d biosynthetic processGO:004236830.558
positive regulation of apoptotic signaling pathwayGO:2001235950.557
regulation of monooxygenase activityGO:003276870.556
fatty acid transportGO:0015908280.556
development of secondary male sexual characteristicsGO:004654430.555
mapk cascadeGO:00001652810.553
female gonad developmentGO:0008585710.552
regulation of chromosome organizationGO:0033044830.544
regulation of carbohydrate catabolic processGO:0043470120.539
purine nucleotide metabolic processGO:00061633020.538
nuclear transportGO:00511691390.537
positive regulation of cell developmentGO:00107202370.537
acid secretionGO:0046717330.537
taurine metabolic processGO:001953040.535
carboxylic acid catabolic processGO:0046395510.535
positive regulation of cell deathGO:00109422240.531
negative regulation of cellular response to insulin stimulusGO:1900077160.530
positive regulation of peptide hormone secretionGO:0090277310.526
regulation of kinase activityGO:00435492490.521
lipid particle organizationGO:003438970.519
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.517
g protein coupled receptor signaling pathway involved in heart processGO:008610340.514
peptidyl lysine acetylationGO:0018394450.510
positive regulation of exit from mitosisGO:003153610.510
epidermis developmentGO:00085441870.509
nucleotide biosynthetic processGO:0009165780.509
response to activityGO:0014823130.507
cellular response to vitamin dGO:007130520.494
cholesterol metabolic processGO:0008203560.494
fat soluble vitamin biosynthetic processGO:004236240.493
astrocyte fate commitmentGO:006001840.493
cellular glucan metabolic processGO:0006073320.492
camp biosynthetic processGO:0006171310.491
cellular carbohydrate catabolic processGO:0044275150.490
jak stat cascadeGO:0007259420.482
protein nitrosylationGO:001701440.481
reactive nitrogen species metabolic processGO:200105700.481
positive regulation of intracellular estrogen receptor signaling pathwayGO:003314840.481
response to ammonium ionGO:0060359210.480
cation transportGO:00068123990.480
adenylate cyclase inhibiting g protein coupled receptor signaling pathwayGO:0007193200.479
regulation of leukocyte apoptotic processGO:2000106560.478
leukocyte apoptotic processGO:0071887710.476
histone acetylationGO:0016573410.475
hair follicle developmentGO:0001942850.470
negative regulation of molecular functionGO:00440922580.468
negative regulation of secretion by cellGO:1903531540.467
triglyceride mobilizationGO:000664250.464
ribonucleotide metabolic processGO:00092592910.464
second messenger mediated signalingGO:0019932730.461
negative regulation of sequestering of triglycerideGO:001089120.459
protein localization to organelleGO:00333651850.457
hormone mediated apoptotic signaling pathwayGO:000862810.455
regulation of glycogen metabolic processGO:0070873130.453
divalent inorganic cation transportGO:00725111780.453
cellular metal ion homeostasisGO:00068751510.451
response to lipopolysaccharideGO:00324961280.451
regulation of vasoconstrictionGO:0019229140.450
aromatic compound catabolic processGO:00194392860.448
allantoin metabolic processGO:000025530.448
heterocycle catabolic processGO:00467002800.447
locomotory behaviorGO:00076261950.445
glucose importGO:0046323320.443
phenol containing compound biosynthetic processGO:0046189210.441
cellular response to external stimulusGO:0071496880.441
regulation of exit from mitosisGO:000709610.441
negative regulation of carbohydrate metabolic processGO:0045912190.440
citrate metabolic processGO:000610130.440
branching morphogenesis of an epithelial tubeGO:00487541590.439
male anatomical structure morphogenesisGO:009059840.438
trophectodermal cell proliferationGO:000183420.438
mammary gland branching involved in pregnancyGO:006074560.436
cell proliferation in hindbrainGO:0021534100.433
bone developmentGO:00603481200.431
response to painGO:0048265260.430
response to ethanolGO:0045471180.430
negative regulation of reactive oxygen species biosynthetic processGO:190342700.427
energy reserve metabolic processGO:0006112390.423
polysaccharide metabolic processGO:0005976390.421
regulation of blood vessel sizeGO:0050880560.417
apoptotic process involved in developmentGO:1902742280.417
regulation of cell motilityGO:20001452360.416
lipid oxidationGO:0034440290.415
ribonucleotide biosynthetic processGO:0009260590.412
positive regulation of histone modificationGO:0031058280.412
cellular divalent inorganic cation homeostasisGO:00725031270.412
antral ovarian follicle growthGO:000154750.409
myeloid cell differentiationGO:00300992330.409
monocarboxylic acid metabolic processGO:00327871910.408
urogenital system developmentGO:00016552610.408
purine nucleoside metabolic processGO:00422782410.406
metal ion homeostasisGO:00550651890.404
response to decreased oxygen levelsGO:0036293590.403
cellular response to inorganic substanceGO:0071241370.401
regulation of secretionGO:00510462740.399
regulation of glucocorticoid secretionGO:200084950.398
response to lithium ionGO:0010226100.398
regulation of hydrolase activityGO:00513362460.391
regulation of histone modificationGO:0031056560.389
glycolytic processGO:0006096200.389
response to amphetamineGO:0001975160.388
histone modificationGO:00165701590.388
stem cell developmentGO:00488642190.381
negative regulation of release of cytochrome c from mitochondriaGO:009020160.381
response to cocaineGO:0042220140.376
neuron migrationGO:00017641220.375
regulation of ion transportGO:00432692150.374
regulation of camp mediated signalingGO:004394970.373
response to hyperoxiaGO:005509320.371
regulation of calcidiol 1 monooxygenase activityGO:006055810.370
ensheathment of neuronsGO:0007272760.370
skeletal system developmentGO:00015013560.368
positive regulation of insulin secretionGO:0032024260.363
response to metal ionGO:0010038470.362
morphogenesis of a branching epitheliumGO:00611381930.361
positive regulation of mammary gland involutionGO:190352140.361
glycogen metabolic processGO:0005977320.360
lipid biosynthetic processGO:00086101790.359
regulation of nucleotide metabolic processGO:00061401690.357
nucleobase containing small molecule metabolic processGO:00550863520.356
response to vitamin aGO:003318910.354
trophectodermal cellular morphogenesisGO:000183130.354
regulation of sequence specific dna binding transcription factor activityGO:00510901060.353
purine containing compound metabolic processGO:00725213110.352
anatomical structure homeostasisGO:00602491450.352
maintenance of locationGO:0051235890.351
cell growthGO:00160491300.350
cellular macromolecule catabolic processGO:00442652060.349
regulation of lymphocyte activationGO:00512492400.346
inflammatory responseGO:00069542440.346
hormone mediated signaling pathwayGO:0009755230.346
purine containing compound biosynthetic processGO:0072522700.345
multicellular organismal metabolic processGO:0044236280.344
regulation of mammary gland involutionGO:190351940.344
primary ovarian follicle growthGO:000154520.344
calcium ion homeostasisGO:00550741270.343
cellular response to steroid hormone stimulusGO:0071383330.342
regulation of purine nucleotide biosynthetic processGO:1900371340.342
regulation of apoptotic signaling pathwayGO:20012331970.341
fear responseGO:0042596330.340
triglyceride biosynthetic processGO:0019432170.338
prostate gland growthGO:0060736130.338
regulation of steroid biosynthetic processGO:0050810260.338
bone morphogenesisGO:0060349780.337
cytokine mediated signaling pathwayGO:00192211150.337
blood circulationGO:00080151950.336
mammary gland morphogenesisGO:0060443540.335
positive regulation of nervous system developmentGO:00519622210.335
learningGO:0007612980.333
cellular ion homeostasisGO:00068731650.332
response to monosaccharideGO:0034284670.331
regulation of mapk cascadeGO:00434082480.331
purine ribonucleotide metabolic processGO:00091502900.329
energy derivation by oxidation of organic compoundsGO:0015980770.329
spinal cord developmentGO:0021510810.327
regulation of cyclic nucleotide biosynthetic processGO:0030802310.325
ovulation cycleGO:0042698590.323
urea metabolic processGO:001962730.323
positive regulation of cyclic nucleotide metabolic processGO:0030801240.318
acylglycerol biosynthetic processGO:0046463180.318
lymphocyte differentiationGO:00300982420.318
response to phenylpropanoidGO:0080184220.318
diacylglycerol metabolic processGO:004633960.316
positive regulation of cytosolic calcium ion concentrationGO:0007204650.314
cation homeostasisGO:00550802120.314
smooth muscle contractionGO:0006939440.308
eating behaviorGO:0042755150.307
sterol metabolic processGO:0016125580.304
corticosterone secretionGO:003593430.303
response to interferon gammaGO:0034341340.303
regulation of steroid hormone biosynthetic processGO:009003040.301
digestive tract developmentGO:00485651900.301
negative regulation of cytokine productionGO:0001818840.300
type b pancreatic cell proliferationGO:0044342100.299
regulation of histone deacetylationGO:0031063120.298
positive regulation of protein modification processGO:00314012990.297
intracellular steroid hormone receptor signaling pathwayGO:0030518290.297
temperature homeostasisGO:0001659260.295
cellular response to glucose stimulusGO:0071333450.295
organonitrogen compound biosynthetic processGO:19015661920.290
phosphatidylinositol 3 kinase signalingGO:0014065360.288
response to oxygen levelsGO:0070482620.288
cellular response to metal ionGO:0071248310.286
wnt signaling pathway involved in kidney developmentGO:006128920.285
regulation of cell morphogenesis involved in differentiationGO:00107691510.285
regulation of peptidyl lysine acetylationGO:2000756220.284
alcohol metabolic processGO:00060661160.282
positive regulation of sodium ion transmembrane transportGO:190230740.281
regulation of multicellular organismal metabolic processGO:0044246140.279
positive regulation of vasoconstrictionGO:004590740.278
steroid hormone mediated signaling pathwayGO:004340160.274
negative regulation of cell proliferationGO:00082852960.272
regulation of osteoblast differentiationGO:0045667670.271
ribose phosphate metabolic processGO:00196932910.271
response to estrogenGO:0043627240.269
regulation of stem cell proliferationGO:0072091780.268
regulation of transmembrane transportGO:00347621280.268
positive regulation of sodium ion transportGO:0010765130.266
intestinal absorptionGO:0050892130.265
positive regulation of cellular response to insulin stimulusGO:190007890.265
hair cycleGO:0042633900.265
response to drugGO:0042493750.263
regulation of phosphatidylinositol 3 kinase signalingGO:0014066300.263
prostate epithelial cord elongationGO:006052330.260
negative regulation of muscle adaptationGO:001474520.260
covalent chromatin modificationGO:00165691630.259
carbohydrate catabolic processGO:0016052320.258
multicellular organismal signalingGO:0035637910.257
regulation of saliva secretionGO:004687720.256
renal system developmentGO:00720012250.256
peptidyl cysteine modificationGO:001819880.255
positive regulation of behaviorGO:0048520400.255
cytosolic calcium ion homeostasisGO:0051480700.254
carbohydrate derivative biosynthetic processGO:19011371830.253
organic hydroxy compound biosynthetic processGO:1901617770.253
platelet derived growth factor receptor signaling pathwayGO:0048008320.253
response to low density lipoprotein particleGO:005509820.250
catecholamine uptake involved in synaptic transmissionGO:005193440.249
cell cell signaling involved in metanephros developmentGO:007220420.248
hemangioblast cell differentiationGO:006021710.247
negative regulation of execution phase of apoptosisGO:190011840.242
multicellular organismal macromolecule metabolic processGO:0044259190.242
response to morphineGO:004327890.242
regulation of sodium ion transportGO:0002028290.242
purine ribonucleotide biosynthetic processGO:0009152590.241
negative regulation of kinase activityGO:0033673810.241
visceral serous pericardium developmentGO:006103220.239
positive regulation of hormone secretionGO:0046887380.239
tissue remodelingGO:00487711020.239
guanosine containing compound metabolic processGO:19010681440.238
response to inorganic substanceGO:0010035960.238
positive regulation of erk1 and erk2 cascadeGO:0070374470.236
negative regulation of nervous system developmentGO:00519611560.236
negative regulation of neurotransmitter uptakeGO:005158120.234
calcium ion transport into cytosolGO:0060402480.234
regulation of calcium ion transportGO:0051924690.233
body fluid secretionGO:0007589530.233
lateral line system developmentGO:004892510.232
regulation of myeloid cell differentiationGO:0045637960.232
response to estradiolGO:0032355120.231
positive regulation of transferase activityGO:00513471670.229
regulation of neuron deathGO:19012141340.229
regulation of lymphocyte proliferationGO:00506701170.228
arginine metabolic processGO:000652520.226
regulation of adrenergic receptor signaling pathwayGO:007187740.225

Lep disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.948
diabetes mellitusDOID:935100.944
type 2 diabetes mellitusDOID:935200.944
carbohydrate metabolism diseaseDOID:005001300.944
glucose metabolism diseaseDOID:419400.944
acquired metabolic diseaseDOID:006015800.944
nutrition diseaseDOID:37400.672
overnutritionDOID:65400.672
inherited metabolic disorderDOID:65500.445