Mus musculus

61 known processes

Lepr

leptin receptor

(Aliases: obl,Leprb,db,MGC105189,OB-RGRP,Modb1,LEPROT,obese-like,Obr,diabetes)

Lepr biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of insulin receptor signaling pathwayGO:0046626211.000
activation of janus kinase activityGO:004297621.000
regulation of activation of jak2 kinase activityGO:001053411.000
cellular response to peptideGO:1901653921.000
regulation of gluconeogenesisGO:0006111301.000
lactationGO:0007595251.000
positive regulation of apoptotic process involved in mammary gland involutionGO:006005841.000
regulation of jak stat cascadeGO:0046425341.000
drug catabolic processGO:004273721.000
mammary gland lobule developmentGO:0061377221.000
positive regulation of fatty acid oxidationGO:004632141.000
negative regulation of cellular response to insulin stimulusGO:1900077161.000
response to peptide hormoneGO:00434341271.000
cellular response to insulin stimulusGO:0032869781.000
jak stat cascadeGO:0007259421.000
neuropeptide signaling pathwayGO:0007218191.000
negative regulation of t helper 2 cell differentiationGO:004562941.000
insulin receptor signaling pathwayGO:0008286491.000
positive regulation of hydrolase activityGO:00513451481.000
cellular response to peptide hormone stimulusGO:0071375921.000
cellular response to organonitrogen compoundGO:00714171451.000
response to peptideGO:19016521361.000
regulation of fatty acid metabolic processGO:0019217281.000
regulation of nitrogen cycle metabolic processGO:190331411.000
creatinine metabolic processGO:004644931.000
positive regulation of insulin receptor signaling pathwayGO:004662841.000
regulation of cellular response to insulin stimulusGO:1900076301.000
regulation of renal output by angiotensinGO:000201921.000
positive regulation of kinase activityGO:00336741551.000
g protein coupled receptor signaling pathwayGO:00071862430.999
regulation of kinase activityGO:00435492490.999
cellular carbohydrate metabolic processGO:00442621190.999
monocarboxylic acid metabolic processGO:00327871910.999
cellular response to amino acid stimulusGO:0071230290.999
negative regulation of protein phosphorylationGO:00019331260.999
layer formation in cerebral cortexGO:0021819130.999
steroid metabolic processGO:00082021190.999
response to insulinGO:00328681000.999
regulation of activation of janus kinase activityGO:001053310.999
response to alcoholGO:0097305480.999
response to organonitrogen compoundGO:00102432460.999
regulation of fatty acid oxidationGO:0046320100.999
tyrosine phosphorylation of stat1 proteinGO:004250830.999
regulation of androgen receptor signaling pathwayGO:006076530.999
mammary gland epithelium developmentGO:0061180650.998
regulation of protein kinase activityGO:00458592320.998
positive regulation of jak stat cascadeGO:0046427220.998
reactive oxygen species biosynthetic processGO:190340980.998
carbohydrate metabolic processGO:00059752300.998
tyrosine phosphorylation of stat proteinGO:0007260230.998
negative regulation of growthGO:0045926990.998
hormone mediated signaling pathwayGO:0009755230.998
fatty acid metabolic processGO:00066311210.998
negative regulation of protein metabolic processGO:00512482820.998
peptidyl tyrosine phosphorylationGO:00181081430.998
negative regulation of insulin receptor signaling pathwayGO:0046627140.998
positive regulation of protein serine threonine kinase activityGO:00719021060.997
positive regulation of protein kinase activityGO:00458601440.997
tyrosine phosphorylation of stat3 proteinGO:0042503120.997
intestinal cholesterol absorptionGO:003029950.997
negative regulation of cellular amino acid metabolic processGO:004576300.997
neuron apoptotic processGO:00514021420.997
Mouse
regulation of cellular ketone metabolic processGO:0010565660.997
negative regulation of peptidyl tyrosine phosphorylationGO:0050732170.997
hexose metabolic processGO:0019318980.997
urogenital system developmentGO:00016552610.997
Mouse
regulation of triglyceride metabolic processGO:0090207170.997
negative regulation of phosphorylationGO:00423261660.996
positive regulation of lymphocyte activationGO:00512511400.996
positive regulation of mapk cascadeGO:00434101700.996
monosaccharide metabolic processGO:00059961060.995
response to amino acidGO:0043200370.995
regulation of glucose metabolic processGO:0010906600.995
cellular response to cytokine stimulusGO:00713451890.995
glucose importGO:0046323320.995
regulation of intestinal cholesterol absorptionGO:003030040.995
intestinal absorptionGO:0050892130.995
erk1 and erk2 cascadeGO:0070371770.995
radial glia guided migration of purkinje cellGO:002194260.994
taurine metabolic processGO:001953040.994
response to organic cyclic compoundGO:00140701980.994
protein kinase c activating g protein coupled receptor signaling pathwayGO:000720540.993
glucose metabolic processGO:0006006920.993
positive regulation of map kinase activityGO:0043406840.993
cellular response to growth hormone stimulusGO:007137870.993
progesterone metabolic processGO:004244840.993
cytokine mediated signaling pathwayGO:00192211150.993
hormone metabolic processGO:0042445860.992
negative regulation of phosphorus metabolic processGO:00105631840.992
metanephric glomerular mesangium developmentGO:007222330.992
creatine metabolic processGO:000660040.992
negative regulation of cell proliferationGO:00082852960.992
cellular amino acid metabolic processGO:00065201030.992
negative regulation of tyrosine phosphorylation of stat3 proteinGO:004251810.992
positive regulation of glial cell proliferationGO:006025240.992
forebrain developmentGO:00309003020.991
alpha amino acid metabolic processGO:1901605590.991
regulation of glutamine family amino acid metabolic processGO:000082010.991
regulation of adrenergic receptor signaling pathwayGO:007187740.990
cellular ketone metabolic processGO:0042180840.990
lipid homeostasisGO:0055088630.990
regulation of secretion by cellGO:19035302490.990
response to hyperoxiaGO:005509320.990
activation of jak2 kinase activityGO:004297720.990
regulation of cellular amine metabolic processGO:0033238200.989
negative regulation of tyrosine phosphorylation of stat proteinGO:004253230.989
regulation of leukocyte differentiationGO:19021051590.989
exogenous drug catabolic processGO:004273810.989
regulation of feeding behaviorGO:006025930.989
regulation of secretionGO:00510462740.989
regulation of ras protein signal transductionGO:00465781140.989
glucose homeostasisGO:00425931280.989
regulation of cellular amino acid metabolic processGO:000652150.989
glycolytic processGO:0006096200.989
negative regulation of cellular amine metabolic processGO:003323910.989
cholesterol esterificationGO:003443530.988
response to corticosteroidGO:0031960200.988
positive regulation of leukocyte differentiationGO:1902107860.988
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathwayGO:005148240.988
negative regulation of phosphate metabolic processGO:00459361840.988
prolactin signaling pathwayGO:003816150.987
mammary gland alveolus developmentGO:0060749220.987
development of primary sexual characteristicsGO:00451371430.987
t cell activationGO:00421102890.986
lipid biosynthetic processGO:00086101790.986
regulation of steroid biosynthetic processGO:0050810260.986
regulation of natural killer cell differentiationGO:0032823110.986
positive regulation of transferase activityGO:00513471670.985
regulation of serotonin uptakeGO:005161120.985
rhythmic processGO:00485111740.984
regulation of hormone levelsGO:00108172110.984
neuron deathGO:00709971540.984
Mouse
regulation of cell migrationGO:00303342190.984
positive regulation of adrenergic receptor signaling pathwayGO:007187930.984
cytokine productionGO:00018163190.984
glycerolipid metabolic processGO:00464861220.983
ammonia assimilation cycleGO:001967620.983
regulation of the force of heart contraction by chemical signalGO:000305750.983
cd4 positive alpha beta t cell activationGO:0035710450.983
small gtpase mediated signal transductionGO:0007264970.983
ras protein signal transductionGO:0007265770.983
adrenal gland developmentGO:0030325180.982
cellular response to acid chemicalGO:0071229680.982
response to bile acidGO:190341210.982
mesonephric tubule developmentGO:0072164940.981
Mouse
carbohydrate biosynthetic processGO:0016051740.981
morphogenesis of a branching structureGO:00017632030.981
fat cell differentiationGO:00454441600.981
cd4 positive alpha beta t cell differentiationGO:0043367410.981
negative regulation of cellular protein metabolic processGO:00322692470.980
telencephalon developmentGO:00215371860.980
regulation of vitamin d biosynthetic processGO:006055610.979
regulation of hydrolase activityGO:00513362460.979
regulation of transferase activityGO:00513382630.979
positive regulation of cyclic nucleotide biosynthetic processGO:0030804240.979
cerebral cortex radial glia guided migrationGO:0021801170.979
negative regulation of molecular functionGO:00440922580.979
response to steroid hormoneGO:0048545560.979
inflammatory responseGO:00069542440.979
positive regulation of dephosphorylationGO:003530660.978
negative regulation of interferon gamma mediated signaling pathwayGO:006033610.978
muscle cell proliferationGO:0033002520.977
alpha beta t cell differentiation involved in immune responseGO:0002293300.977
response to corticosteroneGO:005141210.977
cellular carbohydrate catabolic processGO:0044275150.976
regulation of carbohydrate catabolic processGO:0043470120.975
regulation of tyrosine phosphorylation of stat proteinGO:0042509200.975
cholesterol storageGO:001087840.975
drug metabolic processGO:001714440.975
positive regulation of lymphocyte proliferationGO:0050671700.975
regulation of inflammatory responseGO:00507271470.975
apoptotic process involved in mammary gland involutionGO:006005740.974
multicellular organism growthGO:00352641610.974
leukocyte differentiationGO:00025213420.974
lipid transportGO:0006869980.974
negative regulation of feeding behaviorGO:200025210.974
positive regulation of lipid kinase activityGO:0090218110.973
g protein coupled receptor signaling pathway involved in heart processGO:008610340.973
positive regulation of cholesterol esterificationGO:001087310.973
cellular response to hormone stimulusGO:00328701500.973
cellular response to increased oxygen levelsGO:003629510.973
apoptotic signaling pathwayGO:00971903060.972
regulation of mammary gland involutionGO:190351940.972
positive regulation of t cell activationGO:00508701010.972
allantoin metabolic processGO:000025530.972
labyrinthine layer morphogenesisGO:0060713210.972
cellular response to interferon gammaGO:0071346250.972
regulation of nitric oxide synthase activityGO:005099960.972
regulation of reactive oxygen species biosynthetic processGO:190342620.971
immune effector processGO:00022523210.971
positive regulation of apoptotic signaling pathwayGO:2001235950.971
leukocyte activation involved in immune responseGO:00023661260.971
response to growth hormoneGO:006041670.970
protein nitrosylationGO:001701440.969
t cell differentiationGO:00302171740.969
negative regulation of androgen receptor signaling pathwayGO:006076630.969
energy reserve metabolic processGO:0006112390.968
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediatorGO:190223810.968
regulation of the force of heart contractionGO:0002026170.968
positive regulation of leukocyte proliferationGO:0070665730.968
reactive nitrogen species metabolic processGO:200105700.968
positive regulation of cell activationGO:00508671580.967
negative regulation of neurotransmitter transportGO:005158970.967
negative regulation of response to foodGO:003209670.967
isoleucine metabolic processGO:000654940.967
pallium developmentGO:00215431200.967
negative regulation of neurotrophin trk receptor signaling pathwayGO:005138720.966
carbohydrate catabolic processGO:0016052320.966
mammary gland branching involved in pregnancyGO:006074560.966
mammary gland duct morphogenesisGO:0060603380.966
cell growth involved in cardiac muscle cell developmentGO:006104930.965
epidermal growth factor receptor signaling pathwayGO:0007173280.965
negative regulation of cellular carbohydrate metabolic processGO:0010677190.964
response to campGO:0051591140.964
regulation of protein localizationGO:00328802310.963
regulation of lymphocyte proliferationGO:00506701170.963
regulation of cell activationGO:00508652890.963
succinate metabolic processGO:000610540.962
generation of precursor metabolites and energyGO:00060911030.961
negative regulation of intracellular signal transductionGO:19025321670.958
regulation of carbohydrate metabolic processGO:0006109750.958
regulation of establishment of protein localizationGO:00702011810.958
negative regulation of peptidyl serine phosphorylationGO:0033137100.957
alpha beta t cell activation involved in immune responseGO:0002287310.957
regulation of t helper cell differentiationGO:0045622140.956
regulation of cholesterol esterificationGO:001087220.956
negative regulation of smooth muscle cell apoptotic processGO:003439210.955
positive regulation of erk1 and erk2 cascadeGO:0070374470.955
peptide transportGO:00158331330.954
cellular response to bile acidGO:190341310.953
positive regulation of nucleotide biosynthetic processGO:0030810260.953
negative regulation of systemic arterial blood pressureGO:0003085150.953
adrenergic receptor signaling pathwayGO:0071875130.952
regulation of circadian rhythmGO:0042752580.952
regulation of tyrosine phosphorylation of stat3 proteinGO:0042516100.952
superoxide metabolic processGO:0006801270.952
positive regulation of cell migrationGO:00303351090.951
regulation of cell motilityGO:20001452360.951
sterol homeostasisGO:0055092450.951
intracellular receptor signaling pathwayGO:0030522740.950
cellular response to biotic stimulusGO:0071216920.950
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.950
cerebral cortex developmentGO:0021987860.949
alpha beta t cell differentiationGO:0046632690.948
negative regulation of blood pressureGO:0045776220.948
energy derivation by oxidation of organic compoundsGO:0015980770.947
response to estradiolGO:0032355120.947
trophectodermal cellular morphogenesisGO:000183130.947
renin angiotensin regulation of aldosterone productionGO:000201830.946
regulation of lymphocyte activationGO:00512492400.946
development of primary female sexual characteristicsGO:0046545730.946
regulation of mapk cascadeGO:00434082480.945
regulation of fat cell differentiationGO:0045598810.944
blood circulationGO:00080151950.942
peptidyl tyrosine modificationGO:00182121450.941
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.941
regulation of cellular response to growth factor stimulusGO:0090287820.941
organic hydroxy compound metabolic processGO:19016152030.940
body fluid secretionGO:0007589530.940
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.939
sterol esterificationGO:003443430.938
response to foodGO:0032094170.938
cerebral cortex cell migrationGO:0021795440.937
positive regulation of b cell proliferationGO:0030890240.937
carbohydrate homeostasisGO:00335001280.937
cyclic purine nucleotide metabolic processGO:0052652430.937
acylglycerol metabolic processGO:0006639550.936
monosaccharide biosynthetic processGO:0046364440.936
cholesterol homeostasisGO:0042632440.934
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediatorGO:199012710.932
regulation of erk1 and erk2 cascadeGO:0070372710.932
response to interferon gammaGO:0034341340.931
embryonic placenta developmentGO:0001892980.928
nitric oxide biosynthetic processGO:0006809250.928
regulation of lipid metabolic processGO:00192161180.927
response to glucocorticoidGO:0051384200.926
negative regulation of lymphocyte apoptotic processGO:0070229240.926
positive regulation of vasoconstrictionGO:004590740.926
positive regulation of nervous system developmentGO:00519622210.925
small molecule catabolic processGO:0044282710.924
trophectodermal cell proliferationGO:000183420.924
positive regulation of apoptotic process involved in morphogenesisGO:190233940.923
regulation of t helper 1 cell differentiationGO:004562570.923
positive regulation of nucleoside metabolic processGO:0045979910.923
cellular response to lipidGO:00713961450.923
regulation of tube sizeGO:0035150570.923
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.922
positive regulation of gtpase activityGO:0043547850.922
positive regulation of programmed cell deathGO:00430682180.921
cell proliferation in hindbrainGO:0021534100.920
cellular lipid metabolic processGO:00442553230.920
camp mediated signalingGO:0019933150.920
carbon catabolite activation of transcriptionGO:004599140.920
cellular metal ion homeostasisGO:00068751510.919
regulation of glycogen metabolic processGO:0070873130.919
triglyceride homeostasisGO:0070328150.918
negative regulation of calcium ion transportGO:005192690.916
muscle cell differentiationGO:00426922610.915
regulation of protein transportGO:00512231630.914
regulation of glucagon secretionGO:007009220.914
negative regulation of triglyceride metabolic processGO:009020940.913
regulation of body fluid levelsGO:00508781620.910
sterol transportGO:0015918380.910
regulation of type 2 immune responseGO:0002828180.910
oxidation reduction processGO:00551143420.909
peptide secretionGO:00027901140.909
interleukin 18 mediated signaling pathwayGO:003565520.908
nuclear transportGO:00511691390.908
response to purine containing compoundGO:0014074280.908
positive regulation of nitric oxide synthase activityGO:005100020.907
dendritic spine maintenanceGO:009706240.906
vasodilation by angiotensin involved in regulation of systemic arterial blood pressureGO:000203320.906
response to granulocyte macrophage colony stimulating factorGO:009701230.905
regulation of transcription involved in cell fate commitmentGO:0060850150.905
lymphocyte proliferationGO:00466511640.904
positive regulation of adaptive immune responseGO:0002821610.904
positive regulation of phospholipase activityGO:001051830.904
regulation of glutamate metabolic processGO:200021110.904
regulation of protein serine threonine kinase activityGO:00719001570.904
positive regulation of t helper 1 cell differentiationGO:004562740.904
response to vitamin dGO:003328030.903
regulation of protein targetingGO:1903533610.902
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.902
response to dexamethasoneGO:007154880.902
positive regulation of cellular amine metabolic processGO:003324050.901
lymphocyte activation involved in immune responseGO:0002285930.900
response to estrogenGO:0043627240.898
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.898
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.896
regulation of sequence specific dna binding transcription factor activityGO:00510901060.896
eye photoreceptor cell differentiationGO:0001754410.896
positive regulation of lipid metabolic processGO:0045834400.896
circadian regulation of gene expressionGO:0032922480.895
nitric oxide metabolic processGO:0046209250.894
ossificationGO:00015032160.894
regulation of ammonia assimilation cycleGO:200124810.893
nuclear importGO:0051170950.893
peptidyl amino acid modificationGO:00181933360.892
response to nutrient levelsGO:00316671090.891
regulation of carbohydrate biosynthetic processGO:0043255400.889
cell activation involved in immune responseGO:00022631260.889
female sex differentiationGO:0046660840.885
regulation of glucocorticoid secretionGO:200084950.883
regulation of blood vessel sizeGO:0050880560.883
cytoplasmic transportGO:00164822340.882
steroid hormone mediated signaling pathwayGO:004340160.880
regulation of peptidyl serine phosphorylationGO:0033135390.879
erbb signaling pathwayGO:0038127320.879
regulation of steroid metabolic processGO:0019218390.879
polysaccharide metabolic processGO:0005976390.878
dicarboxylic acid metabolic processGO:0043648180.876
regulation of monooxygenase activityGO:003276870.876
carboxylic acid catabolic processGO:0046395510.876
regulation of cellular carbohydrate metabolic processGO:0010675750.876
positive regulation of cellular response to insulin stimulusGO:190007890.875
regulation of steroid hormone biosynthetic processGO:009003040.873
response to testosteroneGO:003357430.872
angiogenesisGO:00015252010.872
establishment of protein localization to organelleGO:00725941180.872
gluconeogenesisGO:0006094390.870
positive regulation of cytosolic calcium ion concentrationGO:0007204650.869
forebrain cell migrationGO:0021885580.869
citrate metabolic processGO:000610130.868
positive regulation of neuron differentiationGO:00456661410.867
vasodilationGO:0042311280.867
hexose biosynthetic processGO:0019319390.867
morphogenesis of a branching epitheliumGO:00611381930.867
gland developmentGO:00487323300.865
cellular response to vitaminGO:007129520.865
glycogen metabolic processGO:0005977320.865
regulation of ras gtpase activityGO:0032318880.864
response to interleukin 15GO:007067230.863
positive regulation of activated t cell proliferationGO:004210480.863
negative regulation of appetiteGO:003209970.863
female gonad developmentGO:0008585710.862
acylglycerol homeostasisGO:0055090160.861
response to lipopolysaccharideGO:00324961280.861
protein processingGO:00164851630.861
regulation of leukocyte apoptotic processGO:2000106560.860
regulation of lipid kinase activityGO:0043550140.860
intracellular protein transportGO:00068862040.859
leukocyte apoptotic processGO:0071887710.859
negative regulation of protein modification processGO:00314001630.855
protein ubiquitinationGO:00165671710.855
cell type specific apoptotic processGO:00972852680.855
Mouse
cyclic nucleotide mediated signalingGO:0019935180.854
organic acid catabolic processGO:0016054510.853
triglyceride metabolic processGO:0006641510.853
positive regulation of purine nucleotide metabolic processGO:19005441140.853
hindbrain developmentGO:00309021280.852
regulation of dna templated transcription in response to stressGO:004362090.852
response to ethanolGO:0045471180.852
embryonic placenta morphogenesisGO:0060669250.851
cellular lactam metabolic processGO:007233830.850
positive regulation of glycolytic processGO:004582140.850
regulation of fatty acid beta oxidationGO:003199810.848
fat soluble vitamin biosynthetic processGO:004236240.848
regulation of generation of precursor metabolites and energyGO:0043467380.847
regulation of intrinsic apoptotic signaling pathway by p53 class mediatorGO:1902253130.847
lymphocyte differentiationGO:00300982420.846
positive regulation of protein modification processGO:00314012990.846
cerebral cortex radially oriented cell migrationGO:0021799310.845
response to increased oxygen levelsGO:003629620.845
ovulation from ovarian follicleGO:000154290.844
regulation of neuron deathGO:19012141340.842
Mouse
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.842
negative regulation of lipid metabolic processGO:0045833300.840
signal transduction in absence of ligandGO:0038034550.840
intracellular steroid hormone receptor signaling pathwayGO:0030518290.840
branching involved in labyrinthine layer morphogenesisGO:006067090.839
positive regulation of smooth muscle cell migrationGO:001491140.839
activation of cysteine type endopeptidase activityGO:0097202270.838
hindbrain radial glia guided cell migrationGO:0021932120.838
extrinsic apoptotic signaling pathwayGO:00971911260.836
valine metabolic processGO:000657340.836
cerebellar granule cell precursor proliferationGO:0021930100.836
circadian rhythmGO:00076231140.836
negative regulation of inflammatory responseGO:0050728610.836
regulation of response to woundingGO:19030341890.836
response to amphetamineGO:0001975160.836
positive regulation of neuron apoptotic processGO:0043525250.835
fatty acid catabolic processGO:0009062250.834
regulation of glycolytic processGO:0006110100.834
pyruvate metabolic processGO:0006090280.833
arginine metabolic processGO:000652520.832
regulation of cholesterol metabolic processGO:0090181140.831
negative regulation of release of cytochrome c from mitochondriaGO:009020160.830
purine ribonucleotide metabolic processGO:00091502900.830
regulation of cytokine productionGO:00018172660.828
positive regulation of intracellular steroid hormone receptor signaling pathwayGO:003314540.827
regulation of anatomical structure sizeGO:00900661780.827
trophoblast giant cell differentiationGO:0060707150.825
positive regulation of protein phosphorylationGO:00019342420.825
white fat cell differentiationGO:0050872150.825
tyrosine phosphorylation of stat5 proteinGO:004250690.824
regulation of phospholipase c activityGO:190027430.824
positive regulation of apoptotic processGO:00430652170.823
negative regulation of muscle adaptationGO:001474520.822
tor signalingGO:0031929210.822
myotube differentiationGO:00149021050.821
positive regulation of epidermal growth factor receptor signaling pathwayGO:004574250.821
mapk cascadeGO:00001652810.819
vascular process in circulatory systemGO:0003018620.816
positive regulation of mammary gland involutionGO:190352140.816
adipose tissue developmentGO:0060612250.815
keratinocyte migrationGO:005154630.813
negative regulation of serotonin uptakeGO:005161220.813
positive regulation of brown fat cell differentiationGO:009033640.813
cellular response to drugGO:0035690150.810
regulation of appetiteGO:0032098120.810
regulation of homeostatic processGO:00328441820.809
organic hydroxy compound transportGO:0015850930.809
negative regulation of peptide hormone secretionGO:0090278160.809
steroid esterificationGO:003443330.809
positive regulation of glycogen metabolic processGO:007087580.807
regulation of cellular catabolic processGO:00313292420.805
response to epidermal growth factorGO:007084940.805
regulation of t helper 2 cell differentiationGO:004562880.805
regulation of cellular response to stressGO:00801351590.803
positive regulation of carbohydrate metabolic processGO:0045913300.803
regulation of nucleotide biosynthetic processGO:0030808340.802
response to isoquinoline alkaloidGO:001407290.802
intrinsic apoptotic signaling pathway in response to osmotic stressGO:000862720.800
negative regulation of neuron deathGO:1901215980.799
Mouse
pancreas developmentGO:0031016570.799
regulation of peptidase activityGO:0052547960.798
ribonucleotide biosynthetic processGO:0009260590.798
bile acid metabolic processGO:0008206170.797
negative regulation of apoptotic signaling pathwayGO:20012341040.796
regulation of systemic arterial blood pressureGO:0003073610.796
intrinsic apoptotic signaling pathwayGO:00971931320.796
amine metabolic processGO:0009308450.795
glucagon secretionGO:007009130.794
cellular glucan metabolic processGO:0006073320.794
positive regulation of myeloid leukocyte differentiationGO:0002763260.793
epithelial tube morphogenesisGO:00605623030.793
negative regulation of cytosolic calcium ion concentrationGO:005148120.792
glucocorticoid mediated signaling pathwayGO:004340230.792
glucan metabolic processGO:0044042320.791
response to morphineGO:004327890.790
regulation of protein import into nucleusGO:0042306520.790
monocarboxylic acid catabolic processGO:0072329270.789
leukocyte mediated immunityGO:00024431740.788

Lepr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466701.000
inherited metabolic disorderDOID:65501.000
diabetes mellitusDOID:935101.000
type 2 diabetes mellitusDOID:935201.000
carbohydrate metabolism diseaseDOID:005001301.000
glucose metabolism diseaseDOID:419401.000
acquired metabolic diseaseDOID:006015801.000
hypertensionDOID:1076300.871
artery diseaseDOID:005082800.871
disease of anatomical entityDOID:700.871
vascular diseaseDOID:17800.871
essential hypertensionDOID:1082500.871
cardiovascular system diseaseDOID:128700.871
lipid metabolism disorderDOID:314600.836