IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Maged2

melanoma antigen, family D, 2

(Aliases: 4833439A22Rik,ORF1,Mage-d2)

Entrez: 80884
Ensembl: ENSMUSG00000025268
UniProtKB: Q9ER67

Process Predictions
Disease Predictions

Maged2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
regulation of phosphatidylcholine biosynthetic process	GO:2001245	2	0.157
peptidyl amino acid modification	GO:0018193	336	0.118
cellular amino acid metabolic process	GO:0006520	103	0.102
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.094
response to organonitrogen compound	GO:0010243	246	0.067
monocarboxylic acid metabolic process	GO:0032787	191	0.063
regulation of cellular ketone metabolic process	GO:0010565	66	0.058
regulation of cell growth	GO:0001558	91	0.057
peptidyl proline hydroxylation	GO:0019511	3	0.057
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.056
positive regulation of neuron projection development	GO:0010976	79	0.052
long chain fatty acid import	GO:0044539	2	0.051
positive regulation of cell projection organization	GO:0031346	95	0.050
negative regulation of cell proliferation	GO:0008285	296	0.049
ras protein signal transduction	GO:0007265	77	0.045
anion transport	GO:0006820	177	0.044
cell growth	GO:0016049	130	0.044
cellular amine metabolic process	GO:0044106	44	0.042
cellular ketone metabolic process	GO:0042180	84	0.041
positive regulation of cellular amine metabolic process	GO:0033240	5	0.041
wnt signaling pathway	GO:0016055	188	0.040
reactive nitrogen species metabolic process	GO:2001057	0	0.039
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.039
regulation of cell cycle	GO:0051726	281	0.039
regulation of blood pressure	GO:0008217	93	0.038
purine nucleoside metabolic process	GO:0042278	241	0.038
nucleobase containing small molecule metabolic process	GO:0055086	352	0.038
regulation of cell projection organization	GO:0031344	206	0.038
negative regulation of nik nf kappab signaling	GO:1901223	2	0.037
regulation of body fluid levels	GO:0050878	162	0.036
positive regulation of neuron differentiation	GO:0045666	141	0.036
regulation of actin cytoskeleton organization	GO:0032956	84	0.036
nucleoside triphosphate catabolic process	GO:0009143	205	0.035
reactive oxygen species biosynthetic process	GO:1903409	8	0.035
dna metabolic process	GO:0006259	303	0.035
nucleoside catabolic process	GO:0009164	206	0.034
ribose phosphate metabolic process	GO:0019693	291	0.034
regulation of reactive oxygen species biosynthetic process	GO:1903426	2	0.034
blood circulation	GO:0008015	195	0.034
response to organic cyclic compound	GO:0014070	198	0.034
ossification	GO:0001503	216	0.033
ribonucleotide metabolic process	GO:0009259	291	0.033
positive regulation of apoptotic process	GO:0043065	217	0.032
positive regulation of cell development	GO:0010720	237	0.032
regulation of cellular amine metabolic process	GO:0033238	20	0.032
organelle assembly	GO:0070925	177	0.031
purine nucleotide metabolic process	GO:0006163	302	0.031
positive regulation of protein modification process	GO:0031401	299	0.030
positive regulation of protein phosphorylation	GO:0001934	242	0.030
organophosphate catabolic process	GO:0046434	232	0.029
nucleotide metabolic process	GO:0009117	332	0.029
positive regulation of map kinase activity	GO:0043406	84	0.029
regulation of neuron differentiation	GO:0045664	281	0.028
nucleoside metabolic process	GO:0009116	246	0.028
regulation of neuron projection development	GO:0010975	169	0.028
negative regulation of protein metabolic process	GO:0051248	282	0.028
neuron migration	GO:0001764	122	0.028
regulation of apoptotic signaling pathway	GO:2001233	197	0.028
aromatic compound catabolic process	GO:0019439	286	0.028
circulatory system process	GO:0003013	197	0.027
ribonucleotide catabolic process	GO:0009261	208	0.027
regulation of protein kinase activity	GO:0045859	232	0.027
positive regulation of nervous system development	GO:0051962	221	0.027
purine ribonucleotide catabolic process	GO:0009154	208	0.027
rho protein signal transduction	GO:0007266	32	0.027
extracellular matrix organization	GO:0030198	147	0.027
purine ribonucleoside metabolic process	GO:0046128	241	0.026
regulation of cellular amino acid metabolic process	GO:0006521	5	0.026
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.026
carbohydrate derivative catabolic process	GO:1901136	231	0.026
wound healing	GO:0042060	157	0.026
regulation of map kinase activity	GO:0043405	120	0.025
organonitrogen compound catabolic process	GO:1901565	264	0.025
regulation of membrane potential	GO:0042391	192	0.025
gtp catabolic process	GO:0006184	143	0.025
regulation of transferase activity	GO:0051338	263	0.025
small gtpase mediated signal transduction	GO:0007264	97	0.025
reactive oxygen species metabolic process	GO:0072593	84	0.025
regulation of phospholipid biosynthetic process	GO:0071071	3	0.025
macromolecule catabolic process	GO:0009057	281	0.024
cellular chemical homeostasis	GO:0055082	215	0.024
cytoplasmic transport	GO:0016482	234	0.024
protein ubiquitination	GO:0016567	171	0.024
nucleoside triphosphate metabolic process	GO:0009141	230	0.024
membrane organization	GO:0061024	245	0.024
regulation of organelle organization	GO:0033043	289	0.024
negative regulation of molecular function	GO:0044092	258	0.024
positive regulation of programmed cell death	GO:0043068	218	0.024
regulation of cellular component size	GO:0032535	121	0.024
developmental cell growth	GO:0048588	84	0.024
carboxylic acid transport	GO:0046942	100	0.023
glycosyl compound metabolic process	GO:1901657	246	0.023
apoptotic signaling pathway	GO:0097190	306	0.023
regulation of hormone levels	GO:0010817	211	0.023
organonitrogen compound biosynthetic process	GO:1901566	192	0.023
amine metabolic process	GO:0009308	45	0.023
positive regulation of cell death	GO:0010942	224	0.023
engulfment of apoptotic cell	GO:0043652	3	0.023
intracellular protein transport	GO:0006886	204	0.023
regulation of cell size	GO:0008361	72	0.023
positive regulation of protein kinase activity	GO:0045860	144	0.023
cellular nitrogen compound catabolic process	GO:0044270	280	0.023
circadian regulation of gene expression	GO:0032922	48	0.022
regulation of actin nucleation	GO:0051125	4	0.022
nucleoside phosphate catabolic process	GO:1901292	222	0.022
extracellular structure organization	GO:0043062	148	0.022
regulation of secretion	GO:0051046	274	0.022
purine containing compound metabolic process	GO:0072521	311	0.022
lipid localization	GO:0010876	126	0.022
asymmetric stem cell division	GO:0098722	3	0.022
purine nucleoside catabolic process	GO:0006152	205	0.022
calcium ion homeostasis	GO:0055074	127	0.022
response to extracellular stimulus	GO:0009991	127	0.021
regulation of neuron apoptotic process	GO:0043523	122	0.021
immune effector process	GO:0002252	321	0.021
protein catabolic process	GO:0030163	221	0.021
blood coagulation	GO:0007596	76	0.021
circadian rhythm	GO:0007623	114	0.021
negative regulation of immune effector process	GO:0002698	55	0.021
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.021
muscle fiber development	GO:0048747	76	0.021
regulation of multi organism process	GO:0043900	111	0.021
negative regulation of cellular protein metabolic process	GO:0032269	247	0.021
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.021
transmembrane transport	GO:0055085	412	0.021
heterocycle catabolic process	GO:0046700	280	0.021
camera type eye development	GO:0043010	266	0.021
asymmetric neuroblast division	GO:0055059	1	0.021
cellular modified amino acid metabolic process	GO:0006575	63	0.020
compound eye development	GO:0048749	1	0.020
protein maturation	GO:0051604	176	0.020
purine ribonucleotide metabolic process	GO:0009150	290	0.020
small molecule biosynthetic process	GO:0044283	132	0.020
regulation of protein localization	GO:0032880	231	0.020
positive regulation of kinase activity	GO:0033674	155	0.020
male gamete generation	GO:0048232	285	0.020
protein hydroxylation	GO:0018126	4	0.020
response to peptide hormone	GO:0043434	127	0.019
negative regulation of cellular component organization	GO:0051129	194	0.019
axonogenesis	GO:0007409	274	0.019
cell communication by chemical coupling	GO:0010643	2	0.019
negative regulation of intracellular signal transduction	GO:1902532	167	0.019
regulation of kinase activity	GO:0043549	249	0.019
regulation of cellular component biogenesis	GO:0044087	181	0.019
positive regulation of reactive oxygen species biosynthetic process	GO:1903428	2	0.019
actin filament organization	GO:0007015	113	0.019
cellular component assembly involved in morphogenesis	GO:0010927	139	0.019
purine ribonucleoside catabolic process	GO:0046130	205	0.019
regulation of anatomical structure size	GO:0090066	178	0.019
organic acid transport	GO:0015849	101	0.018
monosaccharide transport	GO:0015749	58	0.018
organic anion transport	GO:0015711	137	0.018
negative regulation of cell growth	GO:0030308	44	0.018
citrulline metabolic process	GO:0000052	3	0.018
nitrogen compound transport	GO:0071705	271	0.018
regulation of protein serine threonine kinase activity	GO:0071900	157	0.018
regulation of neuron death	GO:1901214	134	0.018
rhythmic process	GO:0048511	174	0.018
regulation of protein transport	GO:0051223	163	0.018
regulation of circadian rhythm	GO:0042752	58	0.018
organic cyclic compound catabolic process	GO:1901361	295	0.018
positive regulation of mapk cascade	GO:0043410	170	0.018
regulation of secretion by cell	GO:1903530	249	0.018
spermatogenesis	GO:0007283	284	0.018
maintenance of location	GO:0051235	89	0.017
peptidyl proline modification	GO:0018208	6	0.017
positive regulation of defense response	GO:0031349	124	0.017
epithelial cell proliferation	GO:0050673	174	0.017
ribonucleoside catabolic process	GO:0042454	206	0.017
carbohydrate transport	GO:0008643	62	0.017
coagulation	GO:0050817	78	0.017
g protein coupled receptor signaling pathway	GO:0007186	243	0.017
positive regulation of cytokine production	GO:0001819	174	0.017
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.017
lipid biosynthetic process	GO:0008610	179	0.017
response to vitamin a	GO:0033189	1	0.017
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.017
regulation of cytoskeleton organization	GO:0051493	122	0.016
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.016
organism emergence from protective structure	GO:0071684	4	0.016
neuron apoptotic process	GO:0051402	142	0.016
organophosphate biosynthetic process	GO:0090407	122	0.016
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.016
muscle tissue development	GO:0060537	308	0.016
negative regulation of growth	GO:0045926	99	0.016
actin cytoskeleton organization	GO:0030036	220	0.016
response to peptide	GO:1901652	136	0.016
nucleotide catabolic process	GO:0009166	217	0.016
morphogenesis of a branching epithelium	GO:0061138	193	0.016
oxidation reduction process	GO:0055114	342	0.016
peptidyl tyrosine modification	GO:0018212	145	0.016
protein secretion	GO:0009306	111	0.016
regulation of systemic arterial blood pressure	GO:0003073	61	0.015
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	72	0.015
microtubule based process	GO:0007017	236	0.015
t cell activation	GO:0042110	289	0.015
nucleoside phosphate metabolic process	GO:0006753	338	0.015
regulation of defense response	GO:0031347	233	0.015
negative regulation of protein modification process	GO:0031400	163	0.015
alpha amino acid metabolic process	GO:1901605	59	0.015
hormone metabolic process	GO:0042445	86	0.015
phagocytosis	GO:0006909	66	0.015
retrograde transport endosome to golgi	GO:0042147	2	0.015
platelet activation	GO:0030168	40	0.015
glucose transport	GO:0015758	56	0.015
protein targeting	GO:0006605	143	0.015
lipid transport	GO:0006869	98	0.015
ribonucleoside metabolic process	GO:0009119	245	0.014
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.014
chemotaxis	GO:0006935	247	0.014
response to metal ion	GO:0010038	47	0.014
divalent inorganic cation homeostasis	GO:0072507	138	0.014
striated muscle cell development	GO:0055002	125	0.014
nephron tubule morphogenesis	GO:0072078	68	0.014
cell division	GO:0051301	120	0.014
sequestering of calcium ion	GO:0051208	18	0.014
negative regulation of phosphate metabolic process	GO:0045936	184	0.014
inflammatory response	GO:0006954	244	0.014
ear morphogenesis	GO:0042471	118	0.014
regulation of cellular catabolic process	GO:0031329	242	0.014
regulation of system process	GO:0044057	200	0.014
regulation of epithelial cell proliferation	GO:0050678	141	0.014
cation transport	GO:0006812	399	0.014
cellular response to peptide hormone stimulus	GO:0071375	92	0.014
response to vitamin d	GO:0033280	3	0.014
cellular lipid metabolic process	GO:0044255	323	0.014
developmental growth involved in morphogenesis	GO:0060560	138	0.014
protein processing	GO:0016485	163	0.013
development of primary sexual characteristics	GO:0045137	143	0.013
neural precursor cell proliferation	GO:0061351	121	0.013
leukocyte differentiation	GO:0002521	342	0.013
negative regulation of protein phosphorylation	GO:0001933	126	0.013
regulation of intracellular transport	GO:0032386	159	0.013
cilium morphogenesis	GO:0060271	102	0.013
protein modification by small protein conjugation or removal	GO:0070647	207	0.013
cellular response to inorganic substance	GO:0071241	37	0.013
regulation of purine nucleotide metabolic process	GO:1900542	169	0.013
regulation of morphogenesis of a branching structure	GO:0060688	53	0.013
cellular ion homeostasis	GO:0006873	165	0.013
regulation of cell cycle process	GO:0010564	160	0.013
regulation of establishment of protein localization	GO:0070201	181	0.013
actin polymerization or depolymerization	GO:0008154	54	0.013
renal system development	GO:0072001	225	0.013
actin filament polymerization	GO:0030041	44	0.013
response to insulin	GO:0032868	100	0.013
substrate dependent cell migration cell extension	GO:0006930	4	0.013
detection of abiotic stimulus	GO:0009582	60	0.013
cell adhesion	GO:0007155	329	0.013
regulation of organ morphogenesis	GO:2000027	144	0.013
response to acid chemical	GO:0001101	111	0.012
regulation of cell motility	GO:2000145	236	0.012
ameboidal type cell migration	GO:0001667	128	0.012
dna dependent dna replication maintenance of fidelity	GO:0045005	3	0.012
gtp metabolic process	GO:0046039	144	0.012
response to inorganic substance	GO:0010035	96	0.012
skeletal muscle organ development	GO:0060538	163	0.012
multi multicellular organism process	GO:0044706	109	0.012
positive regulation of transferase activity	GO:0051347	167	0.012
purine nucleotide catabolic process	GO:0006195	211	0.012
action potential	GO:0001508	78	0.012
regulation of nucleotide catabolic process	GO:0030811	122	0.012
regulation of protein secretion	GO:0050708	82	0.012
positive regulation of reactive oxygen species metabolic process	GO:2000379	11	0.012
retinol metabolic process	GO:0042572	9	0.012
divalent inorganic cation transport	GO:0072511	178	0.012
fatty acid metabolic process	GO:0006631	121	0.012
regulation of ossification	GO:0030278	112	0.012
cellular response to organonitrogen compound	GO:0071417	145	0.012
dendrite development	GO:0016358	115	0.012
endocytosis	GO:0006897	168	0.012
organic hydroxy compound metabolic process	GO:1901615	203	0.012
regulation of actin filament length	GO:0030832	45	0.011
morphogenesis of a branching structure	GO:0001763	203	0.011
negative regulation of neuron death	GO:1901215	98	0.011
protein modification by small protein conjugation	GO:0032446	187	0.011
negative regulation of microtubule polymerization or depolymerization	GO:0031111	15	0.011
bone development	GO:0060348	120	0.011
purine containing compound catabolic process	GO:0072523	213	0.011
striated muscle tissue development	GO:0014706	293	0.011
multicellular organism growth	GO:0035264	161	0.011
positive regulation of gtp catabolic process	GO:0033126	85	0.011
heart process	GO:0003015	94	0.011
response to radiation	GO:0009314	165	0.011
positive regulation of nucleotide metabolic process	GO:0045981	114	0.011
facioacoustic ganglion development	GO:1903375	3	0.011
glycerophospholipid metabolic process	GO:0006650	71	0.011
regulation of hydrolase activity	GO:0051336	246	0.011
hexose transport	GO:0008645	56	0.011
regulation of leukocyte differentiation	GO:1902105	159	0.011
glycoprotein metabolic process	GO:0009100	116	0.011
regulation of binding	GO:0051098	111	0.011
regulation of fatty acid metabolic process	GO:0019217	28	0.011
metal ion homeostasis	GO:0055065	189	0.011
cell recognition	GO:0008037	83	0.011
primary alcohol metabolic process	GO:0034308	11	0.011
negative regulation of neuron apoptotic process	GO:0043524	92	0.011
response to light stimulus	GO:0009416	135	0.011
carbohydrate derivative biosynthetic process	GO:1901137	183	0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.011
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.011
regulation of nucleotide metabolic process	GO:0006140	169	0.011
carbohydrate metabolic process	GO:0005975	230	0.011
sulfur compound biosynthetic process	GO:0044272	37	0.010
cellular response to dna damage stimulus	GO:0006974	207	0.010
hemostasis	GO:0007599	78	0.010
cytokine production	GO:0001816	319	0.010
regulation of purine nucleotide catabolic process	GO:0033121	122	0.010
regulation of actin filament based process	GO:0032970	99	0.010
innate immune response	GO:0045087	157	0.010
regulation of heart contraction	GO:0008016	77	0.010
cellular protein complex assembly	GO:0043623	116	0.010
protein complex disassembly	GO:0043241	40	0.010
cell type specific apoptotic process	GO:0097285	268	0.010
cell activation involved in immune response	GO:0002263	126	0.010
regulation of fatty acid oxidation	GO:0046320	10	0.010
monocarboxylic acid transport	GO:0015718	44	0.010
chromatin organization	GO:0006325	206	0.010

Maged2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
connective tissue disease	DOID:65	0.014
disease of anatomical entity	DOID:7	0.014
musculoskeletal system disease	DOID:17	0.014
nervous system disease	DOID:863	0.014
bone disease	DOID:0080001	0.011
bone development disease	DOID:0080006	0.011

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