Mus musculus

109 known processes

Mapk8

mitogen-activated protein kinase 8

(Aliases: JNK,Prkm8,JNK1,SAPK1,AI849689)

Mapk8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of jnk cascadeGO:0046328620.994
Fly
regulation of cellular response to stressGO:00801351590.993
Fly
regulation of stress activated mapk cascadeGO:0032872690.990
Fly
stress activated mapk cascadeGO:0051403800.990
release of cytochrome c from mitochondriaGO:0001836230.988
apoptotic mitochondrial changesGO:0008637480.987
jnk cascadeGO:0007254720.987
stress activated protein kinase signaling cascadeGO:0031098810.985
regulation of protein kinase activityGO:00458592320.982
Fly
dna metabolic processGO:00062593030.977
Yeast Rat
regulation of transferase activityGO:00513382630.965
Fly
positive regulation of apoptotic signaling pathwayGO:2001235950.964
regulation of mapk cascadeGO:00434082480.951
Fly
positive regulation of kinase activityGO:00336741550.938
positive regulation of protein kinase activityGO:00458601440.935
regulation of map kinase activityGO:00434051200.926
Fly
positive regulation of protein phosphorylationGO:00019342420.924
mapk cascadeGO:00001652810.922
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361880.912
Yeast
positive regulation of apoptotic processGO:00430652170.901
microtubule based transportGO:0010970500.894
cellular response to dna damage stimulusGO:00069742070.889
Mouse
protein targetingGO:00066051430.859
Mouse
lung developmentGO:00303241640.857
synaptic transmissionGO:00072683290.850
regulation of bindingGO:00510981110.850
Human
regulation of kinase activityGO:00435492490.836
Fly
positive regulation of protein modification processGO:00314012990.819
regulation of apoptotic signaling pathwayGO:20012331970.798
peptidyl serine modificationGO:0018209830.790
Human Mouse
regulation of jun kinase activityGO:0043506400.781
Fly
axonogenesisGO:00074092740.777
Fly
regulation of cellular amine metabolic processGO:0033238200.777
muscle cell differentiationGO:00426922610.765
Mouse
positive regulation of transferase activityGO:00513471670.753
amine metabolic processGO:0009308450.741
defecationGO:003042110.739
positive regulation of jnk cascadeGO:0046330460.739
dna replicationGO:0006260520.735
Yeast Rat
regulation of nuclear cell cycle dna replicationGO:003326220.725
Yeast
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.716
Yeast
apoptotic signaling pathwayGO:00971903060.705
intracellular protein transportGO:00068862040.704
Mouse
wnt signaling pathwayGO:00160551880.692
Mouse
protein localization to organelleGO:00333651850.692
Mouse
homeostasis of number of cellsGO:00488722100.691
Mouse
response to growth factorGO:00708481980.686
positive regulation of programmed cell deathGO:00430682180.684
erythrocyte differentiationGO:0030218880.683
Mouse
cellular response to radiationGO:0071478280.683
positive regulation of mapk cascadeGO:00434101700.674
positive regulation of cell developmentGO:00107202370.674
leukocyte differentiationGO:00025213420.670
Mouse
axon cargo transportGO:0008088330.669
respiratory tube developmentGO:00303231670.668
jun phosphorylationGO:0007258410.667
regulation of cellular catabolic processGO:00313292420.663
Fly
mitochondrion organizationGO:00070051340.662
response to oxidative stressGO:00069791230.656
cytoplasmic transportGO:00164822340.654
Mouse
vesicle localizationGO:0051648860.650
Worm
response to organonitrogen compoundGO:00102432460.641
Mouse
connective tissue developmentGO:00614481790.635
Mouse
meiotic cell cycle processGO:1903046770.634
Yeast
axon guidanceGO:00074111410.634
Fly
negative regulation of phosphorylationGO:00423261660.633
Fly
positive regulation of jun kinase activityGO:0043507300.622
regulation of protein serine threonine kinase activityGO:00719001570.617
Fly
cellular ketone metabolic processGO:0042180840.615
positive regulation of stress activated mapk cascadeGO:0032874480.611
maternal placenta developmentGO:0001893200.607
establishment of protein localization to organelleGO:00725941180.602
Mouse
multicellular organism growthGO:00352641610.597
protein modification by small protein conjugation or removalGO:00706472070.594
organelle localizationGO:00516401790.589
Worm
myeloid cell differentiationGO:00300992330.581
Mouse
proteolysis involved in cellular protein catabolic processGO:00516031470.578
regulation of cellular ketone metabolic processGO:0010565660.578
organelle fissionGO:00482851700.575
negative regulation of cellular protein metabolic processGO:00322692470.574
Fly
negative regulation of cellular amino acid metabolic processGO:004576300.572
multi multicellular organism processGO:00447061090.572
developmental cell growthGO:0048588840.567
Fly
nuclear divisionGO:00002801580.549
peptidyl amino acid modificationGO:00181933360.520
canonical wnt signaling pathwayGO:00600701300.517
Mouse
regulation of dna templated transcription in response to stressGO:004362090.513
Yeast
cellular response to inorganic substanceGO:0071241370.506
response to lipopolysaccharideGO:00324961280.505
Human Mouse
cell divisionGO:00513011200.503
positive regulation of protein serine threonine kinase activityGO:00719021060.500
cytokine productionGO:00018163190.492
response to radiationGO:00093141650.492
Human
positive regulation of cell deathGO:00109422240.490
protein import into nucleusGO:0006606950.486
Mouse
positive regulation of map kinase activityGO:0043406840.480
negative regulation of jun kinase activityGO:004350890.477
Fly
response to inorganic substanceGO:0010035960.475
meiotic cell cycleGO:00513211220.474
Yeast
mitochondrial transportGO:0006839360.472
radial glia guided migration of purkinje cellGO:002194260.464
protein modification by small protein conjugationGO:00324461870.464
skeletal system morphogenesisGO:00487052030.454
Mouse
striated muscle tissue developmentGO:00147062930.452
Mouse
peptidyl threonine phosphorylationGO:0018107310.446
cytoskeleton dependent intracellular transportGO:0030705500.443
response to peptideGO:19016521360.439
Mouse
germ cell developmentGO:00072811850.425
Fly
chromatin modificationGO:00165681870.425
Human
negative regulation of protein phosphorylationGO:00019331260.420
Fly
regulation of protein import into nucleusGO:0042306520.414
Mouse
regulation of dna replicationGO:0006275170.414
Yeast Rat
nucleocytoplasmic transportGO:00069131390.414
Mouse
activation of mapk activityGO:0000187590.409
regulation of membrane potentialGO:00423911920.408
cellular response to oxidative stressGO:0034599760.405
small gtpase mediated signal transductionGO:0007264970.405
intrinsic apoptotic signaling pathwayGO:00971931320.404
neuron projection extensionGO:1990138640.404
Fly
positive regulation of transforming growth factor beta2 productionGO:003291520.401
establishment of organelle localizationGO:00516561220.400
Worm
forebrain developmentGO:00309003020.400
protein autophosphorylationGO:0046777610.399
monocyte differentiationGO:003022490.398
gland developmentGO:00487323300.396
modification dependent protein catabolic processGO:00199411330.395
negative regulation of map kinase activityGO:0043407340.392
Fly
negative regulation of protein metabolic processGO:00512482820.389
Fly
peptidyl threonine modificationGO:0018210310.379
regulation of leukocyte differentiationGO:19021051590.378
establishment of vesicle localizationGO:0051650810.369
Worm
regulation of fibroblast proliferationGO:0048145340.364
regulation of intracellular protein transportGO:0033157820.364
Mouse
response to metal ionGO:0010038470.362
regulation of protein bindingGO:0043393600.360
Human
positive regulation of neuron differentiationGO:00456661410.359
learning or memoryGO:00076111480.354
cell growthGO:00160491300.353
Fly
meiotic nuclear divisionGO:00071261150.353
negative regulation of cell proliferationGO:00082852960.352
microtubule cytoskeleton organizationGO:00002261570.349
Rat
response to molecule of bacterial originGO:00022371430.339
Human Mouse
macromolecule catabolic processGO:00090572810.339
organelle assemblyGO:00709251770.339
single organism nuclear importGO:1902593950.336
Mouse
monocarboxylic acid metabolic processGO:00327871910.331
Mouse
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.331
Mouse
regulation of transforming growth factor beta2 productionGO:003290920.330
myeloid cell homeostasisGO:00022621140.329
Mouse
response to nutrient levelsGO:00316671090.325
cellular amine metabolic processGO:0044106440.321
carbohydrate metabolic processGO:00059752300.321
Mouse
humoral immune responseGO:0006959570.318
Fly
maternal process involved in female pregnancyGO:0060135320.316
regulation of ion transportGO:00432692150.316
ras protein signal transductionGO:0007265770.311
negative regulation of protein modification processGO:00314001630.307
Fly
female gamete generationGO:0007292740.303
Fly
regulation of ras protein signal transductionGO:00465781140.303
positive regulation of neuron apoptotic processGO:0043525250.300
myeloid leukocyte differentiationGO:00025731190.298
Mouse
negative regulation of mapk cascadeGO:0043409650.297
Fly
regulation of defense responseGO:00313472330.292
ossificationGO:00015032160.289
regulation of cellular amino acid metabolic processGO:000652150.288
ubiquitin dependent protein catabolic processGO:00065111290.287
cartilage condensationGO:0001502180.286
Mouse
negative regulation of leukocyte differentiationGO:1902106510.282
regenerationGO:0031099380.279
Mouse Fly
cellular response to arsenic containing substanceGO:007124340.275
Fly
osmosensory signaling pathwayGO:000723110.273
Yeast
negative regulation of phosphorus metabolic processGO:00105631840.272
Fly
cellular response to biotic stimulusGO:0071216920.265
Human Mouse
lung alveolus developmentGO:0048286450.265
embryonic placenta developmentGO:0001892980.263
chemotaxisGO:00069352470.262
Fly
regulation of cytokine productionGO:00018172660.261
spermatogenesisGO:00072832840.260
neuron projection guidanceGO:00974851410.260
Fly
protein ubiquitinationGO:00165671710.260
protein polyubiquitinationGO:0000209330.260
regulation of cell cycleGO:00517262810.260
Yeast
intra s dna damage checkpointGO:003157340.256
response to drugGO:0042493750.252
regulation of myeloid leukocyte differentiationGO:0002761580.251
cognitionGO:00508901490.250
cellular response to starvationGO:0009267570.248
cellular response to transforming growth factor beta stimulusGO:0071560880.246
proteasomal protein catabolic processGO:0010498980.245
pole plasm assemblyGO:000731520.245
heterocycle catabolic processGO:00467002800.245
regulation of feeding behaviorGO:006025930.244
oocyte constructionGO:000730820.243
negative regulation of intracellular signal transductionGO:19025321670.243
Fly
response to osmotic stressGO:0006970210.241
Yeast Rat Worm
positive regulation of intracellular transportGO:0032388700.238
Mouse
regulation of organelle organizationGO:00330432890.237
Human Rat
positive regulation of cellular amine metabolic processGO:003324050.237
regulation of synaptic growth at neuromuscular junctionGO:000858240.235
protein catabolic processGO:00301632210.233
modification dependent macromolecule catabolic processGO:00436321330.232
regulation of canonical wnt signaling pathwayGO:0060828820.231
Mouse
dna damage checkpointGO:0000077260.230
Mouse
negative regulation of bindingGO:0051100390.230
Human
positive regulation of autophagyGO:001050890.228
Fly
positive regulation of ossificationGO:0045778470.225
cellular amino acid metabolic processGO:00065201030.224
microtubule based movementGO:0007018840.222
developmental growth involved in morphogenesisGO:00605601380.219
Fly
positive regulation of protein localization to nucleusGO:1900182300.218
Mouse
photoreceptor cell differentiationGO:0046530520.218
angiogenesisGO:00015252010.216
Mouse
camera type eye developmentGO:00430102660.216
nuclear transportGO:00511691390.216
Mouse
regulation of wnt signaling pathwayGO:00301111230.216
Mouse
cellular response to growth factor stimulusGO:00713631970.214
skeletal system developmentGO:00015013560.212
Mouse
negative regulation of molecular functionGO:00440922580.211
Human Fly
microglial cell activationGO:000177430.208
liver developmentGO:0001889660.207
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.207
negative regulation of lymphocyte activationGO:0051250910.206
synaptic vesicle localizationGO:0097479590.206
negative regulation of cellular amine metabolic processGO:003323910.205
positive regulation of neuron deathGO:1901216280.204
negative regulation of protein serine threonine kinase activityGO:0071901490.204
Fly
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.202
defense response to other organismGO:00985421970.202
Fly
cellular response to nitric oxideGO:007173240.202
positive regulation of nervous system developmentGO:00519622210.201
fat cell differentiationGO:00454441600.200
Mouse
regulation of epithelial cell proliferationGO:00506781410.199
activation of jun kinase activityGO:0007257150.195
myeloid leukocyte activationGO:0002274830.194
protein importGO:00170381010.192
Mouse
peptidyl serine phosphorylationGO:0018105740.192
Human Mouse
regulation of neuron differentiationGO:00456642810.191
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.190
embryonic process involved in female pregnancyGO:006013670.190
myotube differentiationGO:00149021050.189
Mouse
regulation of chromosome organizationGO:0033044830.189
Human
regulation of fat cell differentiationGO:0045598810.189
Mouse
negative regulation of apoptotic signaling pathwayGO:20012341040.183
osteoblast developmentGO:0002076170.181
cellular protein catabolic processGO:00442571550.180
regulation of cytoplasmic transportGO:19036491120.180
Mouse
response to nitric oxideGO:007173140.178
respiratory system developmentGO:00605411900.176
transmembrane transportGO:00550854120.176
regulation of neuron deathGO:19012141340.174
protein homooligomerizationGO:0051260430.173
defense response to bacteriumGO:00427421190.173
Fly
synaptic vesicle transportGO:0048489570.173
positive regulation of cytokine productionGO:00018191740.172
digestive tract morphogenesisGO:00485461470.171
Fly
cellular response to abiotic stimulusGO:0071214560.170
Human Yeast
regulation of reactive oxygen species metabolic processGO:2000377400.169
b cell activationGO:00421131610.168
wound healingGO:00420601570.166
Mouse Fly
circadian rhythmGO:00076231140.166
oocyte differentiationGO:0009994350.164
cellular response to lipidGO:00713961450.163
Human Mouse
protein processingGO:00164851630.163
regulation of myeloid cell differentiationGO:0045637960.163
Mouse
positive regulation of hydrolase activityGO:00513451480.163
Human
negative regulation of cell activationGO:00508661110.162
bmp signaling pathwayGO:0030509930.161
cellular homeostasisGO:00197252400.161
nuclear importGO:0051170950.161
Mouse
hyperosmotic responseGO:000697240.160
Yeast Worm
regulation of cell motilityGO:20001452360.160
Rat
positive regulation of cellular amino acid metabolic processGO:004576430.159
ion transmembrane transportGO:00342203610.159
cellular response to calcium ionGO:0071277140.158
positive regulation of intracellular protein transportGO:0090316420.158
Mouse
labyrinthine layer blood vessel developmentGO:0060716210.157
respiratory gaseous exchangeGO:0007585430.156
positive regulation of osteoblast differentiationGO:0045669340.156
cellular response to cadmium ionGO:007127630.155
Fly
hepaticobiliary system developmentGO:0061008670.155
regulation of cell morphogenesis involved in differentiationGO:00107691510.154
p38mapk cascadeGO:003806640.152
Mouse
response to arsenic containing substanceGO:004668550.149
Yeast Fly
fibroblast proliferationGO:0048144350.149
epithelial cell proliferationGO:00506731740.148
myoblast differentiation involved in skeletal muscle regenerationGO:001483530.148
Mouse
positive regulation of leukocyte differentiationGO:1902107860.146
positive regulation of protein transportGO:0051222930.143
Mouse
regulation of protein homodimerization activityGO:004349640.142
leukocyte proliferationGO:00706611720.141
microtubule based processGO:00070172360.141
Rat
male gamete generationGO:00482322850.140
positive regulation of fibroblast proliferationGO:0048146200.140
dendrite developmentGO:00163581150.139
negative regulation of immune system processGO:00026832090.138
regulation of osteoblast differentiationGO:0045667670.136
regulation of brown fat cell differentiationGO:009033550.135
Mouse
organic cyclic compound catabolic processGO:19013612950.134
cellular response to hormone stimulusGO:00328701500.134
regulation of erythrocyte differentiationGO:0045646230.134
Mouse
regulation of secretionGO:00510462740.133
transforming growth factor beta2 productionGO:003290620.133
matingGO:0007618270.133
synapse organizationGO:00508081250.132
circulatory system processGO:00030131970.131
extrinsic apoptotic signaling pathwayGO:00971911260.131
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.130
negative regulation of phosphate metabolic processGO:00459361840.129
Fly
positive regulation of proteolysisGO:0045862850.128
negative regulation of kinase activityGO:0033673810.127
Fly
autophagyGO:0006914450.125
Fly
cellular response to nutrient levelsGO:0031669640.124
purine containing compound metabolic processGO:00725213110.123
heart processGO:0003015940.122
response to peptide hormoneGO:00434341270.121
heart morphogenesisGO:00030071780.121
translationGO:0006412930.121
erk1 and erk2 cascadeGO:0070371770.120
regulation of cellular component biogenesisGO:00440871810.120
Rat
regulation of proteolysisGO:00301621640.120
programmed necrotic cell deathGO:0097300280.119
blood vessel morphogenesisGO:00485142850.118
Mouse
skeletal muscle organ developmentGO:00605381630.118
Mouse
hematopoietic progenitor cell differentiationGO:00022441430.116
cellular response to osmotic stressGO:007147070.115
Yeast
digestive system developmentGO:00551232000.115
Fly
regulation of autophagyGO:0010506300.114
Fly
response to organic cyclic compoundGO:00140701980.114
Rat
meiosis iGO:0007127600.113
regulation of actin filament based processGO:0032970990.113
fatty acid metabolic processGO:00066311210.113
Mouse
membrane depolarizationGO:0051899640.112
lung morphogenesisGO:0060425500.112
learningGO:0007612980.111
dna integrity checkpointGO:0031570280.109
Mouse
negative regulation of leukocyte proliferationGO:0070664460.108
regulation of erk1 and erk2 cascadeGO:0070372710.108
regulation of receptor activityGO:0010469410.107
nuclear dna replicationGO:003326030.107
Yeast
lipid modificationGO:0030258650.106
Mouse
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787250.105
regulation of hydrolase activityGO:00513362460.105
Human
syncytium formationGO:0006949430.104
Mouse
lymphocyte differentiationGO:00300982420.104
organic anion transportGO:00157111370.103
glucose metabolic processGO:0006006920.103
Mouse
regulation of synapse structural plasticityGO:005182340.102
lymphocyte homeostasisGO:0002260640.102
regionalizationGO:00030023370.101
regulation of neuron apoptotic processGO:00435231220.101
inflammatory responseGO:00069542440.100
Rat
hexose metabolic processGO:0019318980.100
Mouse
multi organism behaviorGO:0051705620.099
stem cell maintenanceGO:00198271300.099
negative regulation of epithelial cell proliferationGO:0050680640.099
phagocytosisGO:0006909660.099
Fly
appendage developmentGO:00487361660.098
regulation of lymphocyte proliferationGO:00506701170.098
cellular response to drugGO:0035690150.098
neuron apoptotic processGO:00514021420.098
cartilage developmentGO:00512161400.097
Mouse
placenta developmentGO:00018901400.097
response to light stimulusGO:00094161350.097
Human
regulation of t cell activationGO:00508631700.096
regulation of protein autophosphorylationGO:003195280.095
cellular response to acid chemicalGO:0071229680.095
oocyte axis specificationGO:000730920.094
jak stat cascadeGO:0007259420.093
stem cell developmentGO:00488642190.092
transforming growth factor beta receptor signaling pathwayGO:0007179710.092
synaptic growth at neuromuscular junctionGO:005112460.091
response to endoplasmic reticulum stressGO:0034976530.091
actin filament based movementGO:0030048230.091
Worm
neuron deathGO:00709971540.090
limb developmentGO:00601731660.090
cellular response to reactive nitrogen speciesGO:190217050.090
positive regulation of reactive oxygen species metabolic processGO:2000379110.090
heart contractionGO:0060047930.089
mitotic cell cycleGO:00002781950.089
organelle disassemblyGO:190300820.089
regulation of inflammatory responseGO:00507271470.089
positive regulation of cellular catabolic processGO:00313311480.088
Fly
lipid homeostasisGO:0055088630.088
positive regulation of organelle organizationGO:00106381280.088
Rat
ovulation cycleGO:0042698590.087
osteoclast differentiationGO:0030316620.087
Mouse
regulation of response to drugGO:200102320.087
regulation of system processGO:00440572000.086
regulation of establishment of protein localizationGO:00702011810.086
Mouse
multicellular organismal reproductive behaviorGO:0033057230.086
regulation of purine nucleotide metabolic processGO:19005421690.085
cellular response to peptideGO:1901653920.083
feeding behaviorGO:0007631620.083
appendage morphogenesisGO:00351071490.083
response to reactive oxygen speciesGO:0000302560.082
cellular macromolecule catabolic processGO:00442652060.082
generation of precursor metabolites and energyGO:00060911030.082
chondrocyte differentiationGO:0002062720.081
Mouse
response to cadmium ionGO:004668680.081
carbohydrate transportGO:0008643620.080
protein oligomerizationGO:0051259670.079
i kappab kinase nf kappab signalingGO:0007249850.079
cellular protein complex assemblyGO:00436231160.078
Rat
regulation of purine nucleotide catabolic processGO:00331211220.078
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.078
cell cycle checkpointGO:0000075470.077
Mouse
cellular response to gamma radiationGO:007148040.077
nucleoside phosphate catabolic processGO:19012922220.077
reactive oxygen species metabolic processGO:0072593840.077
cellular response to molecule of bacterial originGO:0071219830.076
Human Mouse
response to starvationGO:0042594650.076
multicellular organismal signalingGO:0035637910.076
positive regulation of epithelial cell proliferationGO:0050679680.076
regulation of cellular protein catabolic processGO:1903362610.075
immune response activating signal transductionGO:00027571160.075
cellular response to external stimulusGO:0071496880.075
Human
mitochondrial membrane organizationGO:0007006260.075
regulation of lymphocyte differentiationGO:00456191070.074
ribonucleoside catabolic processGO:00424542060.074
regulation of protein transportGO:00512231630.074
Mouse
skeletal muscle cell differentiationGO:0035914660.073
regulation of response to woundingGO:19030341890.073
regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902108140.072
excretionGO:0007588220.072
cellular response to light stimulusGO:0071482190.072
hindbrain radial glia guided cell migrationGO:0021932120.072
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.072
microtubule polymerization or depolymerizationGO:0031109260.071
Rat
cellular ion homeostasisGO:00068731650.071
hexose transportGO:0008645560.071
decidualizationGO:0046697100.070
t cell differentiationGO:00302171740.069
negative regulation of transferase activityGO:0051348850.069
Fly
cation transportGO:00068123990.069
cell maturationGO:00484691270.069
ribonucleotide metabolic processGO:00092592910.069
protein maturationGO:00516041760.069
nitrogen compound transportGO:00717052710.069
response to acid chemicalGO:00011011110.069
oxidation reduction processGO:00551143420.068
Mouse
spermatid differentiationGO:00485151150.067
activation of immune responseGO:00022531380.067
glial cell differentiationGO:00100011310.067
adipose tissue developmentGO:0060612250.067
determination of digestive tract left right asymmetryGO:007190710.067
Fly
lipopolysaccharide mediated signaling pathwayGO:0031663250.067
Mouse
urogenital system developmentGO:00016552610.066
negative regulation of transcription from rna polymerase ii promoter in response to stressGO:009720110.066
reproductive behaviorGO:0019098320.065
regulation of chromatin modificationGO:1903308570.065
Human
t cell activationGO:00421102890.065
rhythmic processGO:00485111740.065
mrna metabolic processGO:0016071840.064
regulation of cell activationGO:00508652890.064
megakaryocyte differentiationGO:0030219260.064
response to extracellular stimulusGO:00099911270.064
epithelial cell developmentGO:00020641590.063
Fly
aromatic compound catabolic processGO:00194392860.063
eye photoreceptor cell developmentGO:0042462310.063
cation homeostasisGO:00550802120.063
stress granule disassemblyGO:003561720.062
glycerolipid biosynthetic processGO:0045017500.062
positive regulation of myeloid cell differentiationGO:0045639430.061
Mouse
positive regulation of growthGO:00459271040.061
histone modificationGO:00165701590.061
Human
regulation of mitochondrial membrane permeabilityGO:0046902170.060
cd4 positive alpha beta t cell activationGO:0035710450.060
macrophage activationGO:0042116270.059
positive regulation of defense responseGO:00313491240.059
negative regulation of growthGO:0045926990.059
oogenesisGO:0048477560.059
Fly
purine ribonucleotide metabolic processGO:00091502900.059
signal transduction by p53 class mediatorGO:0072331510.059
placenta blood vessel developmentGO:0060674310.059
associative learningGO:0008306610.059
negative regulation of wnt signaling pathwayGO:0030178730.059
Mouse
cellular response to metal ionGO:0071248310.058
Fly
response to transforming growth factor betaGO:0071559880.058
regulation of translationGO:0006417710.058
positive regulation of protein import into nucleusGO:0042307260.058
Mouse
multicellular organismal agingGO:0010259240.058
Worm
response to ionizing radiationGO:0010212420.057
positive regulation of rho gtpase activityGO:0032321410.057
cellular chemical homeostasisGO:00550822150.057
regulation of endopeptidase activityGO:0052548890.057
phosphatidylinositol mediated signalingGO:0048015410.057
cellular response to lipopolysaccharideGO:0071222770.057
Human Mouse
regulation of leukocyte proliferationGO:00706631210.057
regulation of histone modificationGO:0031056560.056
Human

Mapk8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.369
disease of cellular proliferationDOID:1456600.369
organ system cancerDOID:005068600.369
heart diseaseDOID:11400.108
disease of anatomical entityDOID:700.108
cardiovascular system diseaseDOID:128700.108