IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Meig1

meiosis expressed gene 1

(Aliases: Meg1)

Ensembl: ENSMUSG00000026650
Entrez: 104362
UniProtKB: Q61845

Process Predictions
Disease Predictions

Meig1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
cilium morphogenesis	GO:0060271	102	0.236
spermatid differentiation	GO:0048515	115	0.161
spermatogenesis	GO:0007283	284	0.134
fertilization	GO:0009566	127	0.086
purine nucleotide metabolic process	GO:0006163	302	0.085
cellular amino acid metabolic process	GO:0006520	103	0.081
cellular ketone metabolic process	GO:0042180	84	0.081
regulation of cellular ketone metabolic process	GO:0010565	66	0.080
cellular lipid metabolic process	GO:0044255	323	0.077
aromatic compound catabolic process	GO:0019439	286	0.076
organelle assembly	GO:0070925	177	0.075
cilium assembly	GO:0042384	81	0.074
inorganic cation transmembrane transport	GO:0098662	207	0.066
germ cell development	GO:0007281	185	0.063
cation transport	GO:0006812	399	0.058
nucleotide metabolic process	GO:0009117	332	0.057
inflammatory response	GO:0006954	244	0.056
cation transmembrane transport	GO:0098655	266	0.056
cellular nitrogen compound catabolic process	GO:0044270	280	0.055
spermatid development	GO:0007286	108	0.053
response to oxidative stress	GO:0006979	123	0.052
nitrogen compound transport	GO:0071705	271	0.052
nucleoside phosphate metabolic process	GO:0006753	338	0.051
oxidation reduction process	GO:0055114	342	0.051
male gamete generation	GO:0048232	285	0.047
purine ribonucleotide metabolic process	GO:0009150	290	0.046
actin filament based movement	GO:0030048	23	0.046
positive regulation of cellular amine metabolic process	GO:0033240	5	0.045
negative regulation of protein phosphorylation	GO:0001933	126	0.045
nucleoside metabolic process	GO:0009116	246	0.044
ribonucleotide metabolic process	GO:0009259	291	0.043
rhodopsin mediated signaling pathway	GO:0016056	4	0.043
microtubule based process	GO:0007017	236	0.043
organophosphate biosynthetic process	GO:0090407	122	0.041
ion transmembrane transport	GO:0034220	361	0.041
mapk cascade	GO:0000165	281	0.041
amine metabolic process	GO:0009308	45	0.041
cellular component assembly involved in morphogenesis	GO:0010927	139	0.039
g protein coupled receptor signaling pathway	GO:0007186	243	0.038
nucleobase containing small molecule metabolic process	GO:0055086	352	0.038
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.038
purine containing compound metabolic process	GO:0072521	311	0.037
actin mediated cell contraction	GO:0070252	15	0.036
fatty acid metabolic process	GO:0006631	121	0.036
transmembrane transport	GO:0055085	412	0.036
regulation of hormone levels	GO:0010817	211	0.035
ribonucleotide catabolic process	GO:0009261	208	0.035
organic cyclic compound catabolic process	GO:1901361	295	0.035
maintenance of location	GO:0051235	89	0.034
regulation of secretion	GO:0051046	274	0.034
organonitrogen compound catabolic process	GO:1901565	264	0.032
sequestering of metal ion	GO:0051238	19	0.032
multicellular organismal signaling	GO:0035637	91	0.032
sperm motility	GO:0030317	47	0.032
locomotory behavior	GO:0007626	195	0.031
nucleotide catabolic process	GO:0009166	217	0.031
regulation of apoptotic signaling pathway	GO:2001233	197	0.029
transmission of nerve impulse	GO:0019226	76	0.029
regulation of cellular amine metabolic process	GO:0033238	20	0.029
microtubule based movement	GO:0007018	84	0.029
peptide secretion	GO:0002790	114	0.029
negative regulation of oxidative stress induced cell death	GO:1903202	9	0.028
purine containing compound biosynthetic process	GO:0072522	70	0.028
cell recognition	GO:0008037	83	0.028
purine ribonucleoside metabolic process	GO:0046128	241	0.028
ribose phosphate metabolic process	GO:0019693	291	0.028
asymmetric neuroblast division	GO:0055059	1	0.027
monosaccharide metabolic process	GO:0005996	106	0.027
carbohydrate derivative biosynthetic process	GO:1901137	183	0.027
respiratory system development	GO:0060541	190	0.027
heterocycle catabolic process	GO:0046700	280	0.026
negative regulation of protein metabolic process	GO:0051248	282	0.026
negative regulation of phosphorus metabolic process	GO:0010563	184	0.026
asymmetric stem cell division	GO:0098722	3	0.026
macromolecule catabolic process	GO:0009057	281	0.026
cellular protein catabolic process	GO:0044257	155	0.026
apoptotic signaling pathway	GO:0097190	306	0.025
negative regulation of homeostatic process	GO:0032845	71	0.025
epithelial cilium movement	GO:0003351	12	0.025
cellular macromolecule catabolic process	GO:0044265	206	0.025
regulation of blood circulation	GO:1903522	93	0.025
heart contraction	GO:0060047	93	0.025
regulation of binding	GO:0051098	111	0.025
regulation of membrane potential	GO:0042391	192	0.024
protein catabolic process	GO:0030163	221	0.024
positive regulation of defense response	GO:0031349	124	0.024
regulation of lipid metabolic process	GO:0019216	118	0.024
amino acid transport	GO:0006865	61	0.024
purine nucleoside metabolic process	GO:0042278	241	0.024
regulation of cellular amino acid metabolic process	GO:0006521	5	0.024
cellular chemical homeostasis	GO:0055082	215	0.024
regulation of inflammatory response	GO:0050727	147	0.023
purine nucleotide catabolic process	GO:0006195	211	0.023
organophosphate catabolic process	GO:0046434	232	0.023
glycosyl compound metabolic process	GO:1901657	246	0.023
glycosyl compound catabolic process	GO:1901658	206	0.023
negative regulation of cellular protein metabolic process	GO:0032269	247	0.023
cellular homeostasis	GO:0019725	240	0.023
lipid biosynthetic process	GO:0008610	179	0.023
retina homeostasis	GO:0001895	23	0.023
myotube differentiation	GO:0014902	105	0.023
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.022
negative regulation of phosphate metabolic process	GO:0045936	184	0.022
carbohydrate derivative catabolic process	GO:1901136	231	0.022
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.021
response to inorganic substance	GO:0010035	96	0.021
circulatory system process	GO:0003013	197	0.021
cellular response to insulin stimulus	GO:0032869	78	0.021
respiratory tube development	GO:0030323	167	0.021
response to vitamin a	GO:0033189	1	0.021
nucleoside monophosphate metabolic process	GO:0009123	85	0.021
inorganic ion transmembrane transport	GO:0098660	234	0.021
protein localization to organelle	GO:0033365	185	0.021
regulation of lymphocyte activation	GO:0051249	240	0.021
cilium movement	GO:0003341	28	0.020
modification dependent macromolecule catabolic process	GO:0043632	133	0.020
neural precursor cell proliferation	GO:0061351	121	0.020
negative regulation of phosphorylation	GO:0042326	166	0.020
male meiosis	GO:0007140	37	0.020
nucleoside phosphate catabolic process	GO:1901292	222	0.020
regulation of purine nucleotide metabolic process	GO:1900542	169	0.020
regulation of monocyte chemotaxis	GO:0090025	3	0.020
negative regulation of cellular amine metabolic process	GO:0033239	1	0.020
cellular amine metabolic process	GO:0044106	44	0.020
lipid modification	GO:0030258	65	0.020
regulation of cell projection organization	GO:0031344	206	0.019
nucleoside triphosphate metabolic process	GO:0009141	230	0.019
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.019
multicellular organismal homeostasis	GO:0048871	164	0.019
regulation of response to wounding	GO:1903034	189	0.019
regulation of mapk cascade	GO:0043408	248	0.019
posttranscriptional regulation of gene expression	GO:0010608	155	0.019
inclusion body assembly	GO:0070841	3	0.019
regulation of muscle system process	GO:0090257	80	0.019
immune effector process	GO:0002252	321	0.019
sensory perception of pain	GO:0019233	47	0.018
regulation of nucleotide catabolic process	GO:0030811	122	0.018
regulation of hydrolase activity	GO:0051336	246	0.018
regulation of cellular catabolic process	GO:0031329	242	0.018
neuron neuron synaptic transmission	GO:0007270	69	0.018
ribonucleoside catabolic process	GO:0042454	206	0.018
regulation of cellular response to stress	GO:0080135	159	0.018
myelination	GO:0042552	74	0.018
response to light stimulus	GO:0009416	135	0.018
regulation of secretion by cell	GO:1903530	249	0.018
sequestering of calcium ion	GO:0051208	18	0.018
innate immune response in mucosa	GO:0002227	3	0.018
organonitrogen compound biosynthetic process	GO:1901566	192	0.018
neuronal action potential	GO:0019228	54	0.018
purine containing compound catabolic process	GO:0072523	213	0.018
intrinsic apoptotic signaling pathway	GO:0097193	132	0.018
regulation of protein catabolic process	GO:0042176	108	0.018
proteasomal protein catabolic process	GO:0010498	98	0.018
regulation of ion transport	GO:0043269	215	0.018
action potential	GO:0001508	78	0.017
ubiquitin dependent protein catabolic process	GO:0006511	129	0.017
nucleotide biosynthetic process	GO:0009165	78	0.017
tissue homeostasis	GO:0001894	115	0.017
monocarboxylic acid metabolic process	GO:0032787	191	0.017
blood circulation	GO:0008015	195	0.017
dna repair	GO:0006281	107	0.017
cellular response to hormone stimulus	GO:0032870	150	0.017
regulation of purine nucleotide catabolic process	GO:0033121	122	0.017
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.017
cofactor metabolic process	GO:0051186	80	0.017
nucleoside catabolic process	GO:0009164	206	0.017
exocytosis	GO:0006887	121	0.017
atp metabolic process	GO:0046034	75	0.017
organic hydroxy compound transport	GO:0015850	93	0.017
negative regulation of protein modification process	GO:0031400	163	0.016
regulation of defense response	GO:0031347	233	0.016
response to reactive oxygen species	GO:0000302	56	0.016
protein modification by small protein conjugation or removal	GO:0070647	207	0.016
myeloid leukocyte mediated immunity	GO:0002444	42	0.016
establishment of organelle localization	GO:0051656	122	0.016
cellular protein complex assembly	GO:0043623	116	0.016
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway	GO:1902176	4	0.016
long chain fatty acid import	GO:0044539	2	0.016
heart process	GO:0003015	94	0.016
response to peptide	GO:1901652	136	0.016
regulation of response to oxidative stress	GO:1902882	19	0.016
response to organonitrogen compound	GO:0010243	246	0.016
binding of sperm to zona pellucida	GO:0007339	34	0.016
response to organic cyclic compound	GO:0014070	198	0.016
regulation of nucleotide metabolic process	GO:0006140	169	0.016
purine nucleotide biosynthetic process	GO:0006164	65	0.016
modification dependent protein catabolic process	GO:0019941	133	0.015
ribonucleoside monophosphate metabolic process	GO:0009161	80	0.015
circadian rhythm	GO:0007623	114	0.015
regulation of multi organism process	GO:0043900	111	0.015
regulation of intrinsic apoptotic signaling pathway	GO:2001242	61	0.015
regulation of ion homeostasis	GO:2000021	64	0.015
sperm egg recognition	GO:0035036	37	0.015
organic anion transport	GO:0015711	137	0.015
carboxylic acid transport	GO:0046942	100	0.015
negative regulation of response to oxidative stress	GO:1902883	10	0.015
carboxylic acid catabolic process	GO:0046395	51	0.015
multi multicellular organism process	GO:0044706	109	0.015
membrane organization	GO:0061024	245	0.015
negative regulation of cellular response to oxidative stress	GO:1900408	10	0.015
regulation of fertilization	GO:0080154	4	0.015
regulation of phospholipid biosynthetic process	GO:0071071	3	0.015
nucleoside triphosphate catabolic process	GO:0009143	205	0.015
negative regulation of cell activation	GO:0050866	111	0.015
regulation of nucleoside metabolic process	GO:0009118	130	0.015
response to molecule of bacterial origin	GO:0002237	143	0.015
amide transport	GO:0042886	138	0.015
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	88	0.015
cellular amide metabolic process	GO:0043603	58	0.015
oocyte construction	GO:0007308	2	0.014
regulation of mitochondrial fission	GO:0090140	3	0.014
purine ribonucleoside catabolic process	GO:0046130	205	0.014
purine nucleoside monophosphate metabolic process	GO:0009126	81	0.014
regulation of hormone secretion	GO:0046883	88	0.014
regulation of cellular component biogenesis	GO:0044087	181	0.014
regulation of proteolysis	GO:0030162	164	0.014
mitochondrion organization	GO:0007005	134	0.014
response to radiation	GO:0009314	165	0.014
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	34	0.014
b cell activation	GO:0042113	161	0.014
regulation of protein maturation	GO:1903317	96	0.014
microtubule cytoskeleton organization	GO:0000226	157	0.014
regulation of cell cycle process	GO:0010564	160	0.014
photoreceptor cell maintenance	GO:0045494	19	0.013
peptidyl serine modification	GO:0018209	83	0.013
cellular response to lipid	GO:0071396	145	0.013
cellular response to arsenic containing substance	GO:0071243	4	0.013
insulin secretion	GO:0030073	89	0.013
camp biosynthetic process	GO:0006171	31	0.013
regulation of homeostatic process	GO:0032844	182	0.013
alcohol metabolic process	GO:0006066	116	0.013
purine ribonucleoside monophosphate metabolic process	GO:0009167	80	0.013
retina development in camera type eye	GO:0060041	119	0.013
mitotic cytokinesis	GO:0000281	4	0.013
fat soluble vitamin biosynthetic process	GO:0042362	4	0.013
regulation of toll like receptor 4 signaling pathway	GO:0034143	4	0.013
fat soluble vitamin metabolic process	GO:0006775	11	0.013
regulation of organelle organization	GO:0033043	289	0.013
cellular response to cadmium ion	GO:0071276	3	0.013
small molecule catabolic process	GO:0044282	71	0.013
meiotic cell cycle	GO:0051321	122	0.013
cardiac muscle contraction	GO:0060048	32	0.013
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.013
negative regulation of phagocytosis	GO:0050765	4	0.013
peptide metabolic process	GO:0006518	46	0.013
regulation of cellular protein catabolic process	GO:1903362	61	0.013
calcium ion homeostasis	GO:0055074	127	0.013
regulation of glucose metabolic process	GO:0010906	60	0.013
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.013
membrane depolarization	GO:0051899	64	0.013
sensory perception	GO:0007600	245	0.013
single fertilization	GO:0007338	82	0.013
purine ribonucleotide biosynthetic process	GO:0009152	59	0.013
cellular response to oxidative stress	GO:0034599	76	0.013
carbohydrate metabolic process	GO:0005975	230	0.013
cellular ion homeostasis	GO:0006873	165	0.013
methylation	GO:0032259	134	0.013
protein targeting	GO:0006605	143	0.013
cyclic purine nucleotide metabolic process	GO:0052652	43	0.012
positive regulation of cellular catabolic process	GO:0031331	148	0.012
ribonucleoside metabolic process	GO:0009119	245	0.012
response to lipopolysaccharide	GO:0032496	128	0.012
positive regulation of cell death	GO:0010942	224	0.012
small molecule biosynthetic process	GO:0044283	132	0.012
lipid catabolic process	GO:0016042	69	0.012
carbohydrate homeostasis	GO:0033500	128	0.012
peptidyl amino acid modification	GO:0018193	336	0.012
regulation of vesicle mediated transport	GO:0060627	139	0.012
phospholipid metabolic process	GO:0006644	87	0.012
nephron epithelium development	GO:0072009	92	0.012
inner dynein arm assembly	GO:0036159	2	0.012
cerebellum development	GO:0021549	77	0.012
multicellular organismal response to stress	GO:0033555	62	0.012
chiasma assembly	GO:0051026	6	0.012
peptide transport	GO:0015833	133	0.012
cerebellar cortex development	GO:0021695	48	0.012
establishment of protein localization to organelle	GO:0072594	118	0.012
microglial cell activation	GO:0001774	3	0.012
endomembrane system organization	GO:0010256	147	0.012
nucleoside monophosphate catabolic process	GO:0009125	59	0.012
adaptation of rhodopsin mediated signaling	GO:0016062	2	0.012
innate immune response	GO:0045087	157	0.012
adult behavior	GO:0030534	135	0.012
regulation of eosinophil migration	GO:2000416	2	0.012
establishment of vesicle localization	GO:0051650	81	0.012
anatomical structure homeostasis	GO:0060249	145	0.012
cellular metal ion homeostasis	GO:0006875	151	0.012
relaxation of muscle	GO:0090075	18	0.012
humoral immune response	GO:0006959	57	0.012
regulation of phosphatidylcholine biosynthetic process	GO:2001245	2	0.012
activation of immune response	GO:0002253	138	0.012
positive regulation of protein modification process	GO:0031401	299	0.012
lymphocyte proliferation	GO:0046651	164	0.012
rhythmic process	GO:0048511	174	0.012
cell cell recognition	GO:0009988	44	0.012
cardiac muscle cell contraction	GO:0086003	7	0.011
response to extracellular stimulus	GO:0009991	127	0.011
localization within membrane	GO:0051668	4	0.011
cd4 positive alpha beta t cell proliferation	GO:0035739	2	0.011
peptidyl serine phosphorylation	GO:0018105	74	0.011
response to nutrient levels	GO:0031667	109	0.011
regionalization	GO:0003002	337	0.011
sulfur compound metabolic process	GO:0006790	100	0.011
glucose metabolic process	GO:0006006	92	0.011
cellular response to biotic stimulus	GO:0071216	92	0.011
maternal determination of anterior posterior axis embryo	GO:0008358	2	0.011
vitamin d biosynthetic process	GO:0042368	3	0.011
regulation of protein localization	GO:0032880	231	0.011
telencephalon development	GO:0021537	186	0.011
positive regulation of transferase activity	GO:0051347	167	0.011
negative regulation of kinase activity	GO:0033673	81	0.011
photoreceptor cell differentiation	GO:0046530	52	0.011
cytosolic calcium ion homeostasis	GO:0051480	70	0.011
cyclic nucleotide metabolic process	GO:0009187	59	0.011
glycerophospholipid metabolic process	GO:0006650	71	0.011
photoreceptor cell development	GO:0042461	40	0.011
regulation of endocytosis	GO:0030100	69	0.011
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.011
regulation of monocyte extravasation	GO:2000437	2	0.011
muscle tissue development	GO:0060537	308	0.011
purine nucleoside catabolic process	GO:0006152	205	0.011
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.011
cytokine production	GO:0001816	319	0.011
anion transport	GO:0006820	177	0.011
regulation of blood pressure	GO:0008217	93	0.011
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.011
circadian regulation of gene expression	GO:0032922	48	0.011
regulation of cell activation	GO:0050865	289	0.011
vesicle localization	GO:0051648	86	0.011
regulation of leukocyte proliferation	GO:0070663	121	0.011
cellular alcohol biosynthetic process	GO:0044108	3	0.011
lipid oxidation	GO:0034440	29	0.011
regulation of mitotic cell cycle phase transition	GO:1901990	73	0.011
activation of adenylate cyclase activity	GO:0007190	4	0.011
cellular response to peptide hormone stimulus	GO:0071375	92	0.011
metal ion homeostasis	GO:0055065	189	0.011
cation homeostasis	GO:0055080	212	0.011
homeostasis of number of cells	GO:0048872	210	0.011
cell activation involved in immune response	GO:0002263	126	0.010
protein localization to nucleus	GO:0034504	121	0.010
unsaturated fatty acid metabolic process	GO:0033559	31	0.010
negative regulation of mitotic cell cycle	GO:0045930	58	0.010
divalent inorganic cation homeostasis	GO:0072507	138	0.010
regulation of lymphocyte proliferation	GO:0050670	117	0.010
macromolecule methylation	GO:0043414	120	0.010
purine ribonucleoside monophosphate catabolic process	GO:0009169	57	0.010
reactive oxygen species metabolic process	GO:0072593	84	0.010
toll like receptor signaling pathway	GO:0002224	38	0.010
vitamin metabolic process	GO:0006766	23	0.010
ribose phosphate biosynthetic process	GO:0046390	59	0.010
oocyte axis specification	GO:0007309	2	0.010
organelle disassembly	GO:1903008	2	0.010
monosaccharide biosynthetic process	GO:0046364	44	0.010
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.010
striated muscle tissue development	GO:0014706	293	0.010
ribonucleoside monophosphate catabolic process	GO:0009158	57	0.010
muscle system process	GO:0003012	141	0.010
p38mapk cascade	GO:0038066	4	0.010
synaptonemal complex organization	GO:0070193	15	0.010
purine nucleoside monophosphate catabolic process	GO:0009128	58	0.010
cellular response to cytokine stimulus	GO:0071345	189	0.010

Meig1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
primary ciliary dyskinesia	DOID:9562	0.126
nervous system disease	DOID:863	0.043
disease of anatomical entity	DOID:7	0.043
sensory system disease	DOID:0050155	0.039
eye and adnexa disease	DOID:1492	0.039
retinal disease	DOID:5679	0.039
eye disease	DOID:5614	0.039
retinal degeneration	DOID:8466	0.039
cardiovascular system disease	DOID:1287	0.018
central nervous system disease	DOID:331	0.017
musculoskeletal system disease	DOID:17	0.015
heart disease	DOID:114	0.015
retinitis pigmentosa	DOID:10584	0.015
disease of cellular proliferation	DOID:14566	0.014
cancer	DOID:162	0.014
organ system cancer	DOID:0050686	0.010
neurodegenerative disease	DOID:1289	0.010

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