| energy derivation by oxidation of organic compounds | GO:0015980 | 77 | 0.880 | |
| oxidation reduction process | GO:0055114 | 342 | 0.715 | Human |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.607 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 85 | 0.483 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.463 | |
| generation of precursor metabolites and energy | GO:0006091 | 103 | 0.448 | |
| cellular respiration | GO:0045333 | 38 | 0.391 | |
| atp metabolic process | GO:0046034 | 75 | 0.333 | |
| oxidative phosphorylation | GO:0006119 | 14 | 0.321 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 80 | 0.268 | |
| hydrogen ion transmembrane transport | GO:1902600 | 25 | 0.265 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.248 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.226 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.207 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.196 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.152 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.142 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.137 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.136 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.126 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.120 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.115 | Human |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 81 | 0.095 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.095 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.093 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.085 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.084 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.080 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 80 | 0.079 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.076 | |
| apoptotic mitochondrial changes | GO:0008637 | 48 | 0.064 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.064 | |
| citrate metabolic process | GO:0006101 | 3 | 0.061 | |
| sulfur compound metabolic process | GO:0006790 | 100 | 0.060 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.057 | |
| cofactor metabolic process | GO:0051186 | 80 | 0.054 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.054 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.052 | |
| monocarboxylic acid metabolic process | GO:0032787 | 191 | 0.051 | |
| coenzyme biosynthetic process | GO:0009108 | 23 | 0.050 | |
| determination of adult lifespan | GO:0008340 | 11 | 0.049 | Worm |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.046 | |
| cation transport | GO:0006812 | 399 | 0.045 | |
| atp synthesis coupled electron transport | GO:0042773 | 8 | 0.043 | |
| transmembrane transport | GO:0055085 | 412 | 0.043 | |
| mitochondrion organization | GO:0007005 | 134 | 0.043 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.042 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.041 | |
| mitochondrial electron transport ubiquinol to cytochrome c | GO:0006122 | 2 | 0.040 | |
| response to oxygen levels | GO:0070482 | 62 | 0.040 | |
| protein maturation | GO:0051604 | 176 | 0.039 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.037 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.036 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.035 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.035 | |
| mitochondrial atp synthesis coupled electron transport | GO:0042775 | 8 | 0.034 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.033 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.033 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.031 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.030 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.029 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.029 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.028 | |
| inflammatory response | GO:0006954 | 244 | 0.028 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.028 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.027 | |
| gonad development | GO:0008406 | 141 | 0.027 | |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.027 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.027 | |
| proton transport | GO:0015992 | 35 | 0.027 | |
| negative regulation of neuron apoptotic process | GO:0043524 | 92 | 0.026 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.026 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.025 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.025 | |
| response to oxidative stress | GO:0006979 | 123 | 0.025 | |
| regulation of neuron death | GO:1901214 | 134 | 0.025 | |
| metallo sulfur cluster assembly | GO:0031163 | 3 | 0.025 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.025 | |
| coenzyme metabolic process | GO:0006732 | 52 | 0.025 | |
| cellular modified amino acid metabolic process | GO:0006575 | 63 | 0.024 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.024 | |
| neural tube formation | GO:0001841 | 108 | 0.024 | |
| negative regulation of neuron death | GO:1901215 | 98 | 0.024 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.023 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.022 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.022 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.022 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.022 | |
| nadh metabolic process | GO:0006734 | 1 | 0.022 | |
| mitochondrial transport | GO:0006839 | 36 | 0.021 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.021 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.021 | Human |
| protein processing | GO:0016485 | 163 | 0.021 | |
| neuron apoptotic process | GO:0051402 | 142 | 0.021 | |
| small molecule biosynthetic process | GO:0044283 | 132 | 0.021 | |
| removal of superoxide radicals | GO:0019430 | 12 | 0.021 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.021 | |
| response to inorganic substance | GO:0010035 | 96 | 0.020 | |
| organic acid biosynthetic process | GO:0016053 | 86 | 0.020 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.020 | |
| regulation of neuron apoptotic process | GO:0043523 | 122 | 0.020 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.019 | |
| regulation of inflammatory response | GO:0050727 | 147 | 0.019 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.019 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 77 | 0.019 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.019 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.018 | |
| regulation of protein complex assembly | GO:0043254 | 83 | 0.018 | |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.018 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.018 | |
| quinone biosynthetic process | GO:1901663 | 4 | 0.018 | |
| microtubule based process | GO:0007017 | 236 | 0.018 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 40 | 0.017 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.017 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.017 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.017 | |
| monocarboxylic acid biosynthetic process | GO:0072330 | 61 | 0.017 | |
| nucleoside monophosphate catabolic process | GO:0009125 | 59 | 0.017 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.017 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.017 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.017 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.016 | |
| response to hypoxia | GO:0001666 | 58 | 0.016 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.016 | |
| small molecule catabolic process | GO:0044282 | 71 | 0.016 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.016 | |
| locomotory behavior | GO:0007626 | 195 | 0.016 | |
| regulation of nucleoside metabolic process | GO:0009118 | 130 | 0.016 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.016 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.016 | |
| negative regulation of proteolysis | GO:0045861 | 74 | 0.016 | |
| protein catabolic process | GO:0030163 | 221 | 0.016 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.015 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 61 | 0.015 | Human |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.015 | |
| intracellular steroid hormone receptor signaling pathway | GO:0030518 | 29 | 0.015 | |
| protein localization to organelle | GO:0033365 | 185 | 0.015 | |
| reactive oxygen species biosynthetic process | GO:1903409 | 8 | 0.015 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.015 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.015 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.015 | |
| neuron death | GO:0070997 | 154 | 0.014 | |
| succinyl coa metabolic process | GO:0006104 | 1 | 0.014 | |
| acyl coa metabolic process | GO:0006637 | 19 | 0.014 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.014 | |
| age dependent general metabolic decline | GO:0007571 | 3 | 0.014 | |
| action potential | GO:0001508 | 78 | 0.014 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.014 | |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 57 | 0.014 | |
| response to decreased oxygen levels | GO:0036293 | 59 | 0.014 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.014 | |
| membrane organization | GO:0061024 | 245 | 0.014 | |
| gland development | GO:0048732 | 330 | 0.014 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 91 | 0.014 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.014 | |
| cellular response to oxidative stress | GO:0034599 | 76 | 0.013 | |
| negative regulation of protein processing | GO:0010955 | 79 | 0.013 | |
| protein oxidation | GO:0018158 | 2 | 0.013 | |
| mitochondrial electron transport nadh to ubiquinone | GO:0006120 | 4 | 0.013 | |
| spermatogenesis | GO:0007283 | 284 | 0.013 | |
| regulation of protein transport | GO:0051223 | 163 | 0.013 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.013 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.013 | |
| atp catabolic process | GO:0006200 | 55 | 0.013 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.013 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.013 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.013 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.013 | Human |
| sensory perception | GO:0007600 | 245 | 0.013 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.013 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.012 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.012 | |
| male gamete generation | GO:0048232 | 285 | 0.012 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.012 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.012 | |
| regulation of reactive oxygen species biosynthetic process | GO:1903426 | 2 | 0.012 | |
| substantia nigra development | GO:0021762 | 2 | 0.012 | Human |
| amine metabolic process | GO:0009308 | 45 | 0.012 | |
| reactive nitrogen species metabolic process | GO:2001057 | 0 | 0.012 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 114 | 0.011 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.011 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.011 | |
| aerobic respiration | GO:0009060 | 7 | 0.011 | |
| positive regulation of reactive oxygen species metabolic process | GO:2000379 | 11 | 0.011 | |
| intracellular protein transport | GO:0006886 | 204 | 0.011 | |
| exocytosis | GO:0006887 | 121 | 0.011 | |
| regulation of neurotransmitter levels | GO:0001505 | 87 | 0.011 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.011 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 159 | 0.011 | |
| regulation of cell activation | GO:0050865 | 289 | 0.011 | |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.011 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.011 | |
| negative regulation of organelle organization | GO:0010639 | 90 | 0.011 | |
| protein ubiquitination | GO:0016567 | 171 | 0.011 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.011 | Human |
| response to reactive oxygen species | GO:0000302 | 56 | 0.010 | |
| positive regulation of cellular respiration | GO:1901857 | 3 | 0.010 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.010 | |
| carboxylic acid biosynthetic process | GO:0046394 | 86 | 0.010 | |
| cofactor biosynthetic process | GO:0051188 | 41 | 0.010 | |
| negative regulation of intrinsic apoptotic signaling pathway | GO:2001243 | 34 | 0.010 | Human |