Mus musculus

627 known processes

Notch1

Notch gene homolog 1 (Drosophila)

(Aliases: 9930111A19Rik,Mis6,lin-12,Tan1)

Notch1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
somite specificationGO:000175741.000
compartment pattern specificationGO:000738641.000
ventricular trabecula myocardium morphogenesisGO:0003222111.000
blood vessel lumenizationGO:007255421.000
regulation of somitogenesisGO:001480761.000
dorsal aorta morphogenesisGO:003591251.000
cell migration involved in endocardial cushion formationGO:000327331.000
neuroblast fate determinationGO:000740011.000
Fly
inner ear receptor cell fate commitmentGO:006012061.000
arterial endothelial cell differentiationGO:006084251.000
lateral inhibitionGO:004633111.000
Fly
endothelial tube morphogenesisGO:006115421.000
morphogenesis of an endotheliumGO:000315921.000
positive regulation of transcription of notch receptor targetGO:000722141.000
blood vessel endothelial cell differentiationGO:006083761.000
segment specificationGO:0007379151.000
regulation of epidermal cell differentiationGO:0045604211.000
ciliary body morphogenesisGO:006107331.000
Mouse
negative regulation of mechanoreceptor differentiationGO:004563231.000
notch signaling involved in heart developmentGO:006131451.000
negative regulation of auditory receptor cell differentiationGO:004560821.000
regulation of auditory receptor cell differentiationGO:004560741.000
clara cell differentiationGO:006048641.000
positive regulation of notch signaling pathwayGO:0045747181.000
Fly
dorsal aorta developmentGO:003590761.000
regulation of pro b cell differentiationGO:200097351.000
embryonic organ morphogenesisGO:00485622761.000
negative regulation of blood vessel endothelial cell migrationGO:004353731.000
Human
negative regulation of epithelial cell migrationGO:001063391.000
Human
epithelial to mesenchymal transition involved in endocardial cushion formationGO:0003198101.000
heart trabecula morphogenesisGO:0061384261.000
regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiationGO:000325661.000
negative regulation of fat cell differentiationGO:0045599361.000
interleukin 4 secretionGO:007260251.000
proximal tubule developmentGO:007201451.000
Mouse
epithelial tube morphogenesisGO:00605623031.000
regulation of astrocyte differentiationGO:0048710200.999
negative regulation of epidermal cell differentiationGO:004560570.999
auditory receptor cell differentiationGO:0042491370.999
negative regulation of endothelial cell migrationGO:001059640.999
Human
notch signaling pathwayGO:0007219710.999
stem cell developmentGO:00488642190.999
cell cell signaling involved in cell fate commitmentGO:0045168350.999
Worm Fly
myeloid cell differentiationGO:00300992330.999
Mouse
sensory organ boundary specificationGO:000805210.999
Fly
atrioventricular node developmentGO:000316230.998
negative regulation of inner ear receptor cell differentiationGO:200098130.998
gamma delta t cell differentiationGO:0042492110.998
stem cell maintenanceGO:00198271300.998
Human Zebrafish Fly
regionalizationGO:00030023370.998
negative regulation of myeloid cell differentiationGO:0045638380.998
regulation of endothelial cell migrationGO:0010594220.997
Human
response to muramyl dipeptideGO:003249590.996
cardiac left ventricle morphogenesisGO:000321490.996
segmentationGO:0035282930.996
negative regulation of epidermis developmentGO:004568390.996
regulation of mechanoreceptor differentiationGO:004563150.996
cardiac ventricle morphogenesisGO:0003208500.996
axonogenesisGO:00074092740.996
positive regulation of cardiac muscle tissue growthGO:0055023150.996
epithelial cell fate commitmentGO:0072148130.995
ephrin receptor signaling pathwayGO:0048013200.995
stem cell differentiationGO:00488632680.995
glial cell migrationGO:000834770.995
Fly
renal tubule developmentGO:0061326870.995
keratinocyte differentiationGO:0030216480.995
mechanoreceptor differentiationGO:0042490670.995
dendritic cell differentiationGO:0097028260.995
Mouse
negative regulation of neuron differentiationGO:00456651010.995
gland developmentGO:00487323300.995
compound eye developmentGO:004874910.994
Fly
pericardium morphogenesisGO:000334450.993
neuroblast differentiationGO:001401620.992
Fly
leukocyte differentiationGO:00025213420.992
Mouse
choline transportGO:001587130.992
somite developmentGO:0061053810.992
endocardium morphogenesisGO:000316060.991
gliogenesisGO:00420631410.991
heart valve morphogenesisGO:0003179210.991
cardiocyte differentiationGO:0035051870.991
regulation of cardiac muscle tissue growthGO:0055021260.991
cardiac cell fate specificationGO:006091220.990
Fly
vascular smooth muscle cell differentiationGO:0035886110.990
cardiac right atrium morphogenesisGO:000321330.990
myeloid dendritic cell differentiationGO:0043011160.990
Mouse
growth involved in heart morphogenesisGO:000324140.990
distal tubule developmentGO:007201780.990
negative regulation of pro b cell differentiationGO:200097410.990
regulation of cardiac cell fate specificationGO:200004310.990
Fly
cardiac muscle cell myoblast differentiationGO:006037980.989
mesenchyme developmentGO:00604851520.989
determination of heart left right asymmetryGO:0061371480.989
hair cell differentiationGO:0035315400.989
skin morphogenesisGO:0043589380.989
glomerular epithelial cell developmentGO:007231060.989
Mouse
endocardial cushion formationGO:0003272130.988
kidney developmentGO:00018222130.988
positive regulation of heart growthGO:0060421180.988
regulation of cardiac muscle tissue developmentGO:0055024310.988
cardiac septum developmentGO:0003279590.988
glial cell fate determinationGO:000740330.988
Fly
cell fate specificationGO:0001708720.987
positive regulation of astrocyte differentiationGO:004871180.987
endocardial cushion cell differentiationGO:006144310.986
inner ear receptor cell differentiationGO:0060113610.986
regulation of cellular amine metabolic processGO:0033238200.986
cell adhesionGO:00071553290.986
Human Fly
regulation of epidermis developmentGO:0045682330.986
regulation of neural retina developmentGO:006107430.986
regulation of inner ear receptor cell differentiationGO:200098050.985
forebrain developmentGO:00309003020.985
regulation of cardioblast differentiationGO:005189030.985
Fly
central nervous system neuron differentiationGO:00219531620.985
Zebrafish
myeloid dendritic cell activationGO:0001773250.985
Mouse
cardiac conduction system developmentGO:0003161120.983
negative regulation of epidermal growth factor activated receptor activityGO:000717530.983
regulation of neuron differentiationGO:00456642810.983
regulation of blood vessel endothelial cell migrationGO:0043535120.983
Human
embryonic heart tube developmentGO:0035050650.982
cardiac septum morphogenesisGO:0060411460.982
regulation of epidermal growth factor activated receptor activityGO:000717670.982
positive regulation of myeloid leukocyte differentiationGO:0002763260.981
Mouse
cardiac neural crest cell differentiation involved in heart developmentGO:006130780.981
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.981
neural tube developmentGO:00219151600.980
regulation of ossificationGO:00302781120.980
glomerular epithelial cell differentiationGO:0072311100.980
Mouse
endocardial cushion developmentGO:0003197260.980
cardiac muscle tissue morphogenesisGO:0055008440.979
cardiac chamber developmentGO:00032051080.979
cardiac chamber morphogenesisGO:0003206930.978
regulation of osteoblast differentiationGO:0045667670.978
left right pattern formationGO:0060972230.978
germ line stem cell maintenanceGO:003071860.978
Fly
positive regulation of cardiac muscle tissue developmentGO:0055025190.977
epidermis developmentGO:00085441870.977
regulation of neural precursor cell proliferationGO:2000177700.977
Rat
somitogenesisGO:0001756690.977
cardiac neural crest cell development involved in heart developmentGO:006130870.977
regulation of cardiac muscle cell proliferationGO:0060043230.977
negative regulation of hematopoietic progenitor cell differentiationGO:190153340.976
bmp signaling pathwayGO:0030509930.975
ventricular cardiac muscle tissue morphogenesisGO:0055010320.974
cardiac cell developmentGO:0055006410.974
nephron developmentGO:00720061090.974
embryonic heart tube morphogenesisGO:0003143510.974
endocardial cushion cell developmentGO:006144410.973
mesenchymal cell differentiationGO:00487621070.973
negative regulation of molecular functionGO:00440922580.972
positive regulation of keratinocyte differentiationGO:004561830.972
t cell activationGO:00421102890.971
hematopoietic progenitor cell differentiationGO:00022441430.970
mesoderm developmentGO:00074981000.970
Zebrafish Fly
mesenchymal cell developmentGO:0014031930.970
cell surface receptor signaling pathway involved in heart developmentGO:0061311150.970
glomerular mesangial cell developmentGO:007214430.970
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.969
epithelial cell apoptotic process involved in palatal shelf morphogenesisGO:199013410.968
regulation of mitotic cell cycle phase transitionGO:1901990730.968
Fly
endocardial cushion morphogenesisGO:0003203180.967
positive regulation of cardiac muscle cell proliferationGO:0060045150.966
ventral spinal cord interneuron differentiationGO:0021514160.966
blood vessel endothelial cell migrationGO:0043534230.966
Human
renal system developmentGO:00720012250.965
aortic valve morphogenesisGO:000318040.965
Human
ossificationGO:00015032160.965
endoplasmic reticulum calcium ion homeostasisGO:0032469110.964
regulation of cellular ketone metabolic processGO:0010565660.964
response to symbiontGO:000960820.963
Fly
striated muscle tissue developmentGO:00147062930.962
regulation of myeloid cell differentiationGO:0045637960.962
Mouse
positive regulation of cardiac muscle cell differentiationGO:200072760.962
loop of henle developmentGO:0072070100.960
negative regulation of glial cell proliferationGO:006025340.960
lymphocyte differentiationGO:00300982420.959
embryonic skeletal system developmentGO:00487061200.959
pulmonary valve morphogenesisGO:000318450.959
Human
regulation of gliogenesisGO:0014013500.958
atrioventricular valve morphogenesisGO:0003181130.958
epithelial cell differentiation involved in kidney developmentGO:0035850230.957
apoptotic process involved in embryonic digit morphogenesisGO:190226330.956
cardiac right ventricle morphogenesisGO:0003215130.956
epidermal cell fate specificationGO:000995710.955
regulation of fat cell differentiationGO:0045598810.955
cardiac endothelial cell differentiationGO:000334840.955
branching morphogenesis of an epithelial tubeGO:00487541590.955
negative regulation of glial cell differentiationGO:0045686210.954
cardiac atrium developmentGO:0003230240.953
striated muscle cell proliferationGO:0014855390.952
aorta morphogenesisGO:0035909220.952
epithelial cell proliferationGO:00506731740.951
cardiac neural crest cell development involved in outflow tract morphogenesisGO:006130960.950
apoptotic process involved in morphogenesisGO:0060561250.949
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.949
negative regulation of protein phosphorylationGO:00019331260.948
positive regulation of cell cycle g1 s phase transitionGO:190280890.947
Fly
cardiac muscle cell differentiationGO:0055007690.947
regulation of cellular amino acid metabolic processGO:000652150.947
ventricular cardiac muscle tissue developmentGO:0003229380.946
nephron epithelium developmentGO:0072009920.945
cerebral cortex neuron differentiationGO:0021895190.944
urogenital system developmentGO:00016552610.943
tissue migrationGO:0090130680.943
Human Fly
appendage morphogenesisGO:00351071490.942
negative regulation of notch signaling pathwayGO:0045746140.939
anagenGO:0042640130.938
paraxial mesoderm developmentGO:0048339180.937
negative regulation of cellular amine metabolic processGO:003323910.935
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.935
pericardium developmentGO:0060039160.934
muscle tissue developmentGO:00605373080.934
epithelial to mesenchymal transitionGO:0001837470.934
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoterGO:007236470.934
regulation of mitotic cell cycleGO:00073461260.933
Fly
myeloid leukocyte activationGO:0002274830.929
Mouse
response to peptideGO:19016521360.929
formation of organ boundaryGO:001016010.929
Fly
regulation of notch signaling pathwayGO:0008593350.928
Fly
wnt signaling pathwayGO:00160551880.928
gamma delta t cell activationGO:0046629130.927
negative regulation of oligodendrocyte differentiationGO:0048715110.927
blood vessel morphogenesisGO:00485142850.925
regulation of bindingGO:00510981110.924
canonical wnt signaling pathway involved in heart developmentGO:006131630.924
response to oxygen levelsGO:0070482620.923
regulation of cell cycle phase transitionGO:1901987770.920
Fly
regulation of glial cell differentiationGO:0045685410.919
negative regulation of photoreceptor cell differentiationGO:004653340.919
venous blood vessel developmentGO:0060841130.918
i kappab phosphorylationGO:000725260.917
Fly
cardiac muscle tissue developmentGO:00487381300.917
positive regulation of epithelial to mesenchymal transitionGO:0010718130.916
regulation of leukocyte differentiationGO:19021051590.916
Mouse
regulation of retina development in camera type eyeGO:190286630.916
positive regulation of mitotic cell cycle phase transitionGO:1901992170.913
Fly
outflow tract morphogenesisGO:0003151530.913
sprouting angiogenesisGO:0002040260.912
regulation of cell migrationGO:00303342190.911
organelle assemblyGO:00709251770.909
placenta blood vessel developmentGO:0060674310.908
Mouse
negative regulation of peptidyl tyrosine phosphorylationGO:0050732170.906
mitotic cell cycle processGO:19030471590.905
Fly
cardiac muscle tissue growthGO:0055017370.905
negative regulation of ossificationGO:0030279490.900
negative regulation of neuron projection developmentGO:0010977500.899
venous blood vessel morphogenesisGO:004884570.899
myeloid leukocyte differentiationGO:00025731190.897
Mouse
ear developmentGO:00435832000.896
secondary heart field specificationGO:000313960.896
nephron tubule developmentGO:0072080840.896
mitotic cell cycleGO:00002781950.893
Fly
skeletal system developmentGO:00015013560.891
negative regulation of calcium ion dependent exocytosisGO:004595530.889
negative regulation of cell developmentGO:00107211690.886
kidney epithelium developmentGO:00720731210.885
axon guidanceGO:00074111410.881
Fly
determination of left right symmetryGO:0007368800.881
negative regulation of nervous system developmentGO:00519611560.879
regulation of resting membrane potentialGO:006007530.879
endothelium developmentGO:0003158450.879
heart morphogenesisGO:00030071780.878
regulation of bmp signaling pathwayGO:0030510600.878
positive regulation of osteoblast differentiationGO:0045669340.877
cell fate commitment involved in pattern specificationGO:0060581140.876
Fly
ventricular septum morphogenesisGO:0060412270.875
Human
heart valve developmentGO:0003170230.873
muscle cell differentiationGO:00426922610.872
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.871
regulation of neuron projection developmentGO:00109751690.870
hepaticobiliary system developmentGO:0061008670.870
positive regulation of myeloid cell differentiationGO:0045639430.868
Mouse
ameboidal type cell migrationGO:00016671280.868
Human Fly
aorta developmentGO:0035904230.866
canonical wnt signaling pathwayGO:00600701300.862
positive regulation of osteoclast differentiationGO:0045672150.862
Mouse
cell fate determinationGO:0001709320.861
Fly
developmental maturationGO:00217001930.859
somatic stem cell maintenanceGO:0035019470.859
interleukin 4 productionGO:0032633240.857
positive regulation of mitotic cell cycleGO:0045931410.857
Fly
labyrinthine layer blood vessel developmentGO:0060716210.856
positive regulation of g1 s transition of mitotic cell cycleGO:190008790.855
Fly
negative regulation of protein tyrosine kinase activityGO:006109930.854
neural precursor cell proliferationGO:00613511210.854
Rat
neuron projection guidanceGO:00974851410.852
Fly
negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902042110.849
cellular response to starvationGO:0009267570.848
regulation of oligodendrocyte differentiationGO:0048713230.847
negative regulation of cell proliferationGO:00082852960.846
activation of mapkk activityGO:0000186150.846
lymph vessel morphogenesisGO:0036303110.845
Zebrafish
regulation of epithelial cell migrationGO:0010632350.843
Human
apoptotic process involved in developmentGO:1902742280.842
regulation of g1 s transition of mitotic cell cycleGO:2000045350.841
Fly
carbohydrate derivative biosynthetic processGO:19011371830.840
limb developmentGO:00601731660.838
spinal cord developmentGO:0021510810.838
Zebrafish Rat
glomerulus developmentGO:0032835400.835
glomerular mesangial cell differentiationGO:007200830.833
peripheral nervous system developmentGO:0007422530.833
Zebrafish Fly
exocytosisGO:00068871210.832
cardioblast proliferationGO:000326380.830
Rat
negative regulation of ligase activityGO:005135230.830
positive regulation of epidermal cell differentiationGO:004560660.828
regulation of transcription from rna polymerase ii promoter involved in heart developmentGO:190121390.827
positive regulation of mapk cascadeGO:00434101700.827
thymic t cell selectionGO:0045061220.827
positive regulation of apoptotic processGO:00430652170.827
regulation of peptidyl tyrosine phosphorylationGO:0050730930.824
cellular response to dna damage stimulusGO:00069742070.821
glial cell proliferationGO:0014009100.816
positive regulation of muscle tissue developmentGO:1901863320.814
cardiac right ventricle formationGO:000321930.814
regulation of cardiac muscle cell differentiationGO:200072590.812
regulation of cell morphogenesis involved in differentiationGO:00107691510.810
glomerular capillary formationGO:007210460.809
Mouse
endocardial cell differentiationGO:006095640.807
regulation of epithelial cell proliferation involved in prostate gland developmentGO:0060768100.807
pallium developmentGO:00215431200.806
cell fate commitmentGO:00451652100.806
regulation of epithelial to mesenchymal transitionGO:0010717220.802
copper ion transportGO:0006825100.798
regulation of ubiquitin protein transferase activityGO:005143870.797
positive regulation of apoptotic signaling pathwayGO:2001235950.796
positive regulation of cell developmentGO:00107202370.795
negative regulation of cell motilityGO:2000146610.790
Human
heart growthGO:0060419450.788
cellular ketone metabolic processGO:0042180840.788
neuroblast fate commitmentGO:001401710.786
Fly
regulation of cell motilityGO:20001452360.784
regulation of myeloid leukocyte differentiationGO:0002761580.783
Mouse
camera type eye developmentGO:00430102660.783
Mouse
respiratory system developmentGO:00605411900.783
skeletal system morphogenesisGO:00487052030.782
embryonic placenta developmentGO:0001892980.781
blood circulationGO:00080151950.780
cardiac muscle cell proliferationGO:0060038310.778
regulation of cardioblast proliferationGO:000326490.776
neuronal stem cell maintenanceGO:0097150170.774
Human Zebrafish
gonad developmentGO:00084061410.773
Worm
trabecula morphogenesisGO:0061383400.773
g1 s transition of mitotic cell cycleGO:0000082570.771
Fly
cellular component assembly involved in morphogenesisGO:00109271390.770
Fly
cerebral cortex developmentGO:0021987860.768
negative regulation of protein modification processGO:00314001630.767
cell type specific apoptotic processGO:00972852680.767
memoryGO:0007613580.766
Fly
regulation of cell cycle g1 s phase transitionGO:1902806350.764
Fly
astrocyte differentiationGO:0048708430.762
vesicle localizationGO:0051648860.761
regulation of stem cell differentiationGO:2000736500.761
mesangial cell differentiationGO:007200740.761
regulation of sequence specific dna binding transcription factor activityGO:00510901060.760
heart field specificationGO:000312860.760
humoral immune responseGO:0006959570.759
morphogenesis of an epithelial sheetGO:0002011270.757
cardiac epithelial to mesenchymal transitionGO:0060317180.756
cardiac vascular smooth muscle cell developmentGO:006094830.752
midbrain hindbrain boundary morphogenesisGO:002155540.751
positive regulation of ossificationGO:0045778470.745
striated muscle cell developmentGO:00550021250.745
Human
extrinsic apoptotic signaling pathwayGO:00971911260.743
morphogenesis of embryonic epitheliumGO:00163311590.742
negative regulation of cell migrationGO:0030336590.738
Human
glial cell fate commitmentGO:0021781140.737
Fly
morphogenesis of a branching epitheliumGO:00611381930.737
oogenesisGO:0048477560.735
Fly
erythrocyte differentiationGO:0030218880.734
regulation of proteasomal protein catabolic processGO:0061136460.733
positive regulation of cell cycleGO:0045787920.732
Fly
muscle tissue morphogenesisGO:0060415530.732
glomerular visceral epithelial cell developmentGO:007201560.728
Mouse
fat cell differentiationGO:00454441600.726
t cell differentiationGO:00302171740.721
regulation of heart growthGO:0060420310.721
positive regulation of gliogenesisGO:0014015270.720
kidney interstitial fibroblast differentiationGO:007207150.715
positive regulation of epithelial cell proliferationGO:0050679680.714
mesenchyme morphogenesisGO:0072132320.713
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.709
respiratory tube developmentGO:00303231670.707
defense response to other organismGO:00985421970.706
Mouse
positive regulation of transcription from rna polymerase ii promoter in response to hypoxiaGO:006141910.701
epidermis morphogenesisGO:0048730330.700
muscle system processGO:00030121410.696
regulation of extracellular matrix assemblyGO:190120120.692
thymus developmentGO:0048538410.692
artery developmentGO:0060840530.691
cell proliferation involved in heart morphogenesisGO:0061323150.688
Rat
cytokine secretionGO:0050663720.687
chromatin organizationGO:00063252060.686
positive regulation of cell deathGO:00109422240.686
angiogenesisGO:00015252010.686
negative regulation of kinase activityGO:0033673810.685
liver developmentGO:0001889660.685
regulation of organ morphogenesisGO:20000271440.679
regulation of cell cycleGO:00517262810.675
Worm Fly
regulation of photoreceptor cell differentiationGO:004653240.673
photoreceptor cell differentiationGO:0046530520.672
negative regulation of dendritic spine morphogenesisGO:006100230.669
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.666
hematopoietic stem cell differentiationGO:006021880.663
anatomical structure maturationGO:0071695490.662
columnar cuboidal epithelial cell differentiationGO:0002065820.658
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.657
organelle fissionGO:00482851700.650
Worm
positive regulation of bmp signaling pathwayGO:0030513230.650
rhombomere morphogenesisGO:002159320.649
Zebrafish
negative regulation of osteoblast differentiationGO:0045668300.645
regulation of receptor recyclingGO:000191980.645
single organism cell adhesionGO:00986021560.645
neural tube patterningGO:0021532430.644
negative regulation of leukocyte differentiationGO:1902106510.643
neuron migrationGO:00017641220.642
glial cell differentiationGO:00100011310.641
lung developmentGO:00303241640.640
regulation of cell cycle processGO:00105641600.639
Worm Fly
oligodendrocyte differentiationGO:0048709530.630
regulation of dna templated transcription in response to stressGO:004362090.628
regulation of ligase activityGO:0051340100.626
photoreceptor cell morphogenesisGO:000859430.622
negative regulation of cell morphogenesis involved in differentiationGO:0010771480.617
endothelial cell differentiationGO:0045446410.616
negative regulation of protein bindingGO:0032091170.611
rhombomere formationGO:002159410.607
Zebrafish
left right axis specificationGO:0070986130.607
respiratory system processGO:0003016250.597
heart formationGO:0060914160.596
Rat
stem cell fate commitmentGO:004886550.594
Fly
negative regulation of immune system processGO:00026832090.590
negative regulation of cellular protein catabolic processGO:1903363220.587
t cell receptor signaling pathwayGO:0050852460.585
regulation of keratinocyte differentiationGO:0045616110.585
regulation of secondary heart field cardioblast proliferationGO:000326690.580
regulation of organ growthGO:0046620610.578
skin developmentGO:00435882200.571
t cell differentiation in thymusGO:0033077770.570
regulation of protein serine threonine kinase activityGO:00719001570.569
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:200005960.569
cognitionGO:00508901490.563
Fly
face morphogenesisGO:0060325290.563
positive regulation of map kinase activityGO:0043406840.562
negative regulation of astrocyte differentiationGO:0048712100.562
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.562
cell migration involved in heart developmentGO:006097380.560
regulation of calcium ion dependent exocytosisGO:0017158160.559
positive regulation of leukocyte differentiationGO:1902107860.559
Mouse
pigment cell differentiationGO:0050931270.549
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742400.548
Fly
germ cell developmentGO:00072811850.548
Fly
cell fate determination involved in pattern specificationGO:006058210.546
Fly
positive regulation of cell fate commitmentGO:001045580.546
Zebrafish
embryonic limb morphogenesisGO:00303261260.543
circulatory system processGO:00030131970.542
regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902041220.540
vascular smooth muscle cell developmentGO:009708470.539
mitral valve developmentGO:000317440.538
Human
tissue remodelingGO:00487711020.536
regulation of proteolysisGO:00301621640.536
blood vessel remodelingGO:0001974330.535
regulation of jak stat cascadeGO:0046425340.534
cardioblast differentiationGO:0010002130.532
autophagyGO:0006914450.531
negative regulation of myotube differentiationGO:001083290.528
coronary vasculature morphogenesisGO:006097790.526
establishment of synaptic vesicle localizationGO:0097480570.525
l amino acid transportGO:0015807320.519
negative regulation of ubiquitin protein transferase activityGO:005144430.519
regulation of chromosome organizationGO:0033044830.517
proteolysis involved in cellular protein catabolic processGO:00516031470.517
muscle cell proliferationGO:0033002520.516
protein glycosylationGO:0006486550.504
germ line stem cell divisionGO:004207820.501
cell cycle g1 s phase transitionGO:0044843570.497
Fly
negative regulation of cell cycleGO:00457861230.496
hair follicle morphogenesisGO:0031069290.496
negative regulation of epithelial cell proliferationGO:0050680640.494

Notch1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.974
Human
cardiovascular system diseaseDOID:128700.974
Human
disease of cellular proliferationDOID:1456600.964
myopathyDOID:42300.962
muscular diseaseDOID:008000000.962
heart diseaseDOID:11400.962
Human
cardiomyopathyDOID:005070000.962
dilated cardiomyopathyDOID:1293000.962
intrinsic cardiomyopathyDOID:006003600.962
musculoskeletal system diseaseDOID:1700.962
muscle tissue diseaseDOID:6600.962
gastrointestinal system diseaseDOID:7700.901
hepatobiliary diseaseDOID:311800.788
liver diseaseDOID:40900.788
disease of mental healthDOID:15000.555
cognitive disorderDOID:156100.555
dementiaDOID:130700.499
alzheimer s diseaseDOID:1065200.499
central nervous system diseaseDOID:33100.499
tauopathyDOID:68000.499
neurodegenerative diseaseDOID:128900.499
nervous system diseaseDOID:86300.499