IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Osbp

oxysterol binding protein

(Aliases: AW559088,KIAA4220,mKIAA4220,1110018F06Rik)

Entrez: 76303
Ensembl: ENSMUSG00000024687
UniProtKB: Q3B7Z2

Process Predictions
Disease Predictions

Osbp biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
response to endoplasmic reticulum stress	GO:0034976	53	0.141
male gamete generation	GO:0048232	285	0.049
nucleobase containing small molecule metabolic process	GO:0055086	352	0.045
ribose phosphate metabolic process	GO:0019693	291	0.044
spermatogenesis	GO:0007283	284	0.044
nucleotide metabolic process	GO:0009117	332	0.040
cytoplasmic transport	GO:0016482	234	0.039
transmembrane transport	GO:0055085	412	0.038
purine nucleotide metabolic process	GO:0006163	302	0.038
modification dependent macromolecule catabolic process	GO:0043632	133	0.036
cation transport	GO:0006812	399	0.035
protein catabolic process	GO:0030163	221	0.034
maintenance of location	GO:0051235	89	0.033
intracellular protein transport	GO:0006886	204	0.033
oxidation reduction process	GO:0055114	342	0.031
cellular ketone metabolic process	GO:0042180	84	0.031
negative regulation of molecular function	GO:0044092	258	0.031
microtubule cytoskeleton organization	GO:0000226	157	0.031
cellular nitrogen compound catabolic process	GO:0044270	280	0.031
organic cyclic compound catabolic process	GO:1901361	295	0.031
organophosphate catabolic process	GO:0046434	232	0.031
morphogenesis of embryonic epithelium	GO:0016331	159	0.030
aromatic compound catabolic process	GO:0019439	286	0.030
cellular macromolecule catabolic process	GO:0044265	206	0.030
ubiquitin dependent protein catabolic process	GO:0006511	129	0.030
skeletal system development	GO:0001501	356	0.029
nucleoside phosphate metabolic process	GO:0006753	338	0.029
peptidyl amino acid modification	GO:0018193	336	0.029
purine containing compound catabolic process	GO:0072523	213	0.029
heterocycle catabolic process	GO:0046700	280	0.029
protein modification by small protein conjugation	GO:0032446	187	0.029
regulation of secretion	GO:0051046	274	0.028
glycosyl compound catabolic process	GO:1901658	206	0.028
localization within membrane	GO:0051668	4	0.028
cellular amino acid metabolic process	GO:0006520	103	0.027
protein ubiquitination	GO:0016567	171	0.027
regulation of cellular amine metabolic process	GO:0033238	20	0.027
negative regulation of phosphorylation	GO:0042326	166	0.027
cellular protein catabolic process	GO:0044257	155	0.026
negative regulation of intracellular signal transduction	GO:1902532	167	0.026
ossification	GO:0001503	216	0.026
cellular amine metabolic process	GO:0044106	44	0.026
regulation of hydrolase activity	GO:0051336	246	0.026
microtubule based process	GO:0007017	236	0.026
regulation of neuron differentiation	GO:0045664	281	0.026
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.025
regulation of cellular amino acid metabolic process	GO:0006521	5	0.025
organonitrogen compound catabolic process	GO:1901565	264	0.025
carbohydrate derivative catabolic process	GO:1901136	231	0.025
chromatin modification	GO:0016568	187	0.025
nucleoside phosphate catabolic process	GO:1901292	222	0.025
protein modification by small protein conjugation or removal	GO:0070647	207	0.024
nucleotide catabolic process	GO:0009166	217	0.024
er nucleus signaling pathway	GO:0006984	27	0.024
apoptotic signaling pathway	GO:0097190	306	0.024
regulation of membrane potential	GO:0042391	192	0.023
purine ribonucleotide metabolic process	GO:0009150	290	0.023
regionalization	GO:0003002	337	0.023
germ cell development	GO:0007281	185	0.023
nucleoside catabolic process	GO:0009164	206	0.023
glycoprotein metabolic process	GO:0009100	116	0.023
cellular homeostasis	GO:0019725	240	0.023
action potential	GO:0001508	78	0.023
chromatin organization	GO:0006325	206	0.023
dna metabolic process	GO:0006259	303	0.023
monocarboxylic acid metabolic process	GO:0032787	191	0.023
nucleoside metabolic process	GO:0009116	246	0.022
endomembrane system organization	GO:0010256	147	0.022
sensory perception	GO:0007600	245	0.022
carbohydrate metabolic process	GO:0005975	230	0.022
cation transmembrane transport	GO:0098655	266	0.022
glucose homeostasis	GO:0042593	128	0.022
kidney development	GO:0001822	213	0.022
ribonucleotide metabolic process	GO:0009259	291	0.022
small gtpase mediated signal transduction	GO:0007264	97	0.021
purine ribonucleoside metabolic process	GO:0046128	241	0.021
purine containing compound metabolic process	GO:0072521	311	0.021
regulation of cellular catabolic process	GO:0031329	242	0.021
respiratory system development	GO:0060541	190	0.021
regulation of ion transport	GO:0043269	215	0.021
cellular lipid metabolic process	GO:0044255	323	0.020
modification dependent protein catabolic process	GO:0019941	133	0.020
regulation of cellular component biogenesis	GO:0044087	181	0.020
myeloid cell differentiation	GO:0030099	233	0.020
organelle localization	GO:0051640	179	0.020
lung development	GO:0030324	164	0.020
negative regulation of phosphorus metabolic process	GO:0010563	184	0.020
negative regulation of protein metabolic process	GO:0051248	282	0.020
macromolecule catabolic process	GO:0009057	281	0.020
exocytosis	GO:0006887	121	0.020
ribonucleoside metabolic process	GO:0009119	245	0.020
regulation of cellular ketone metabolic process	GO:0010565	66	0.020
cartilage development	GO:0051216	140	0.020
copii coated vesicle budding	GO:0090114	2	0.019
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.019
cellular chemical homeostasis	GO:0055082	215	0.019
ras protein signal transduction	GO:0007265	77	0.019
purine nucleotide catabolic process	GO:0006195	211	0.019
ion transmembrane transport	GO:0034220	361	0.019
regulation of cell cycle	GO:0051726	281	0.019
negative regulation of phosphate metabolic process	GO:0045936	184	0.019
carbohydrate derivative biosynthetic process	GO:1901137	183	0.019
ribonucleotide catabolic process	GO:0009261	208	0.019
regulation of ossification	GO:0030278	112	0.019
regulation of cell activation	GO:0050865	289	0.019
anion transport	GO:0006820	177	0.019
oocyte axis specification	GO:0007309	2	0.019
misfolded protein transport	GO:0070843	1	0.018
cellular response to topologically incorrect protein	GO:0035967	25	0.018
cell division	GO:0051301	120	0.018
cellular response to growth factor stimulus	GO:0071363	197	0.018
retrograde vesicle mediated transport golgi to er	GO:0006890	1	0.018
response to organonitrogen compound	GO:0010243	246	0.018
neuronal action potential	GO:0019228	54	0.018
nuclear transport	GO:0051169	139	0.018
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.018
amine metabolic process	GO:0009308	45	0.018
divalent inorganic cation transport	GO:0072511	178	0.018
response to organic cyclic compound	GO:0014070	198	0.018
gland development	GO:0048732	330	0.018
connective tissue development	GO:0061448	179	0.017
cellular response to organonitrogen compound	GO:0071417	145	0.017
anion transmembrane transport	GO:0098656	71	0.017
epithelial tube morphogenesis	GO:0060562	303	0.017
inorganic cation transmembrane transport	GO:0098662	207	0.017
locomotory behavior	GO:0007626	195	0.017
respiratory tube development	GO:0030323	167	0.017
methylation	GO:0032259	134	0.017
establishment or maintenance of cytoskeleton polarity	GO:0030952	2	0.017
glycosyl compound metabolic process	GO:1901657	246	0.017
cation homeostasis	GO:0055080	212	0.017
inorganic ion transmembrane transport	GO:0098660	234	0.017
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.017
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.017
endocytosis	GO:0006897	168	0.016
carbohydrate homeostasis	GO:0033500	128	0.016
regulation of body fluid levels	GO:0050878	162	0.016
positive regulation of cellular catabolic process	GO:0031331	148	0.016
negative regulation of cell proliferation	GO:0008285	296	0.016
tube formation	GO:0035148	140	0.016
nucleocytoplasmic transport	GO:0006913	139	0.016
proteasomal protein catabolic process	GO:0010498	98	0.016
purine nucleoside metabolic process	GO:0042278	241	0.016
membrane organization	GO:0061024	245	0.016
protein localization to nucleus	GO:0034504	121	0.016
oocyte construction	GO:0007308	2	0.016
renal system development	GO:0072001	225	0.016
purine ribonucleoside catabolic process	GO:0046130	205	0.015
multicellular organismal signaling	GO:0035637	91	0.015
olfactory learning	GO:0008355	2	0.015
sulfur compound metabolic process	GO:0006790	100	0.015
striated muscle tissue development	GO:0014706	293	0.015
transmission of nerve impulse	GO:0019226	76	0.015
sensory perception of mechanical stimulus	GO:0050954	107	0.015
reactive oxygen species metabolic process	GO:0072593	84	0.015
response to unfolded protein	GO:0006986	21	0.015
metal ion homeostasis	GO:0055065	189	0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.015
sensory organ morphogenesis	GO:0090596	242	0.015
mapk cascade	GO:0000165	281	0.015
biomineral tissue development	GO:0031214	64	0.015
organelle assembly	GO:0070925	177	0.015
lipid biosynthetic process	GO:0008610	179	0.015
response to extracellular stimulus	GO:0009991	127	0.015
morphogenesis of a branching structure	GO:0001763	203	0.015
dephosphorylation	GO:0016311	129	0.015
ribonucleoside catabolic process	GO:0042454	206	0.015
negative regulation of protein modification process	GO:0031400	163	0.015
lateral inhibition	GO:0046331	1	0.015
macromolecule glycosylation	GO:0043413	55	0.015
negative regulation of cellular component organization	GO:0051129	194	0.015
posttranscriptional regulation of gene expression	GO:0010608	155	0.015
embryonic organ morphogenesis	GO:0048562	276	0.014
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.014
purine nucleoside catabolic process	GO:0006152	205	0.014
histone modification	GO:0016570	159	0.014
cellular carbohydrate metabolic process	GO:0044262	119	0.014
purine ribonucleotide catabolic process	GO:0009154	208	0.014
response to inorganic substance	GO:0010035	96	0.014
compound eye development	GO:0048749	1	0.014
response to radiation	GO:0009314	165	0.014
regulation of nucleoside metabolic process	GO:0009118	130	0.014
spermatid development	GO:0007286	108	0.014
lipid localization	GO:0010876	126	0.014
bone development	GO:0060348	120	0.014
intrinsic apoptotic signaling pathway	GO:0097193	132	0.014
positive regulation of cellular amine metabolic process	GO:0033240	5	0.014
regulation of apoptotic signaling pathway	GO:2001233	197	0.014
negative regulation of nervous system development	GO:0051961	156	0.014
protein maturation	GO:0051604	176	0.014
nucleoside triphosphate metabolic process	GO:0009141	230	0.014
spermatid differentiation	GO:0048515	115	0.014
immune effector process	GO:0002252	321	0.014
bone mineralization	GO:0030282	54	0.014
protein localization to membrane	GO:0072657	108	0.013
regulation of hormone levels	GO:0010817	211	0.013
homeostasis of number of cells	GO:0048872	210	0.013
protein targeting	GO:0006605	143	0.013
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.013
protein localization to organelle	GO:0033365	185	0.013
forebrain development	GO:0030900	302	0.013
guanosine containing compound catabolic process	GO:1901069	144	0.013
positive regulation of cell development	GO:0010720	237	0.013
regulation of homeostatic process	GO:0032844	182	0.013
protein glycosylation	GO:0006486	55	0.013
nucleoside triphosphate catabolic process	GO:0009143	205	0.013
learning or memory	GO:0007611	148	0.013
endoplasmic reticulum unfolded protein response	GO:0030968	19	0.013
asymmetric stem cell division	GO:0098722	3	0.013
regulation of cell migration	GO:0030334	219	0.013
leukocyte differentiation	GO:0002521	342	0.013
myotube differentiation	GO:0014902	105	0.013
covalent chromatin modification	GO:0016569	163	0.013
divalent metal ion transport	GO:0070838	172	0.013
regulation of ion transmembrane transport	GO:0034765	119	0.013
nitrogen compound transport	GO:0071705	271	0.013
rho protein signal transduction	GO:0007266	32	0.013
intracellular mrna localization	GO:0008298	4	0.013
protein alkylation	GO:0008213	81	0.013
carbon catabolite activation of transcription	GO:0045991	4	0.013
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	88	0.013
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	1	0.013
cellularization	GO:0007349	1	0.013
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.013
retrograde transport endosome to golgi	GO:0042147	2	0.013
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.013
muscle tissue development	GO:0060537	308	0.013
embryonic skeletal system development	GO:0048706	120	0.012
regulation of nucleotide metabolic process	GO:0006140	169	0.012
fatty acid metabolic process	GO:0006631	121	0.012
developmental maturation	GO:0021700	193	0.012
epithelial cell proliferation	GO:0050673	174	0.012
response to topologically incorrect protein	GO:0035966	25	0.012
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.012
macromolecule methylation	GO:0043414	120	0.012
regulation of anatomical structure size	GO:0090066	178	0.012
skeletal system morphogenesis	GO:0048705	203	0.012
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.012
regulation of response to drug	GO:2001023	2	0.012
negative regulation of growth	GO:0045926	99	0.012
cellular protein complex assembly	GO:0043623	116	0.012
meiotic cell cycle	GO:0051321	122	0.012
mitotic cell cycle	GO:0000278	195	0.012
cardiac muscle cell contraction	GO:0086003	7	0.012
sequestering of metal ion	GO:0051238	19	0.012
skin development	GO:0043588	220	0.012
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.012
regulation of voltage gated calcium channel activity	GO:1901385	4	0.012
oocyte anterior posterior axis specification	GO:0007314	2	0.012
regulation of secretion by cell	GO:1903530	249	0.012
response to growth factor	GO:0070848	198	0.012
organelle fission	GO:0048285	170	0.012
circadian rhythm	GO:0007623	114	0.012
regulation of transforming growth factor beta receptor signaling pathway	GO:0017015	43	0.012
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.011
multicellular organismal homeostasis	GO:0048871	164	0.011
organonitrogen compound biosynthetic process	GO:1901566	192	0.011
leukocyte mediated immunity	GO:0002443	174	0.011
regulation of vesicle mediated transport	GO:0060627	139	0.011
cellular response to hormone stimulus	GO:0032870	150	0.011
positive regulation of programmed cell death	GO:0043068	218	0.011
cell type specific apoptotic process	GO:0097285	268	0.011
regulation of organelle organization	GO:0033043	289	0.011
carboxylic acid catabolic process	GO:0046395	51	0.011
regulation of intrinsic apoptotic signaling pathway	GO:2001242	61	0.011
regulation of lymphocyte activation	GO:0051249	240	0.011
calcium ion transport	GO:0006816	159	0.011
organic hydroxy compound metabolic process	GO:1901615	203	0.011
epithelial cell development	GO:0002064	159	0.011
wound healing	GO:0042060	157	0.011
maternal determination of anterior posterior axis embryo	GO:0008358	2	0.011
stem cell differentiation	GO:0048863	268	0.011
regulation of lipid metabolic process	GO:0019216	118	0.011
cognition	GO:0050890	149	0.011
formation of primary germ layer	GO:0001704	77	0.011
regulation of metal ion transport	GO:0010959	106	0.011
branching morphogenesis of an epithelial tube	GO:0048754	159	0.011
neural precursor cell proliferation	GO:0061351	121	0.011
positive regulation of protein modification process	GO:0031401	299	0.011
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.011
cytokine production	GO:0001816	319	0.011
generation of precursor metabolites and energy	GO:0006091	103	0.011
glycoprotein biosynthetic process	GO:0009101	89	0.011
blood circulation	GO:0008015	195	0.011
cellular response to external stimulus	GO:0071496	88	0.011
negative regulation of cellular protein metabolic process	GO:0032269	247	0.011
zygotic determination of anterior posterior axis embryo	GO:0007354	3	0.011
neural tube formation	GO:0001841	108	0.011
cellular ion homeostasis	GO:0006873	165	0.011
regulation of translation	GO:0006417	71	0.011
divalent inorganic cation homeostasis	GO:0072507	138	0.011
actin filament based movement	GO:0030048	23	0.011
regulation of protein localization	GO:0032880	231	0.011
striated muscle contraction	GO:0006941	45	0.011
b cell activation	GO:0042113	161	0.011
plasma membrane organization	GO:0007009	90	0.011
mitochondrion distribution	GO:0048311	4	0.011
positive regulation of nervous system development	GO:0051962	221	0.011
myeloid leukocyte differentiation	GO:0002573	119	0.011
actin mediated cell contraction	GO:0070252	15	0.011
rna interference	GO:0016246	2	0.011
response to nutrient levels	GO:0031667	109	0.011
calcium ion homeostasis	GO:0055074	127	0.011
regulation of system process	GO:0044057	200	0.011
regulation of purine nucleotide catabolic process	GO:0033121	122	0.011
negative regulation of type b pancreatic cell apoptotic process	GO:2000675	3	0.011
sensory perception of sound	GO:0007605	97	0.011
cofactor metabolic process	GO:0051186	80	0.011
cytokinetic process	GO:0032506	2	0.010
positive regulation of cell death	GO:0010942	224	0.010
muscle system process	GO:0003012	141	0.010
response to light stimulus	GO:0009416	135	0.010
protein methylation	GO:0006479	81	0.010
extracellular matrix organization	GO:0030198	147	0.010
neural tube development	GO:0021915	160	0.010
skeletal muscle organ development	GO:0060538	163	0.010
regulation of hormone secretion	GO:0046883	88	0.010
chondrocyte differentiation	GO:0002062	72	0.010
regulation of cell motility	GO:2000145	236	0.010
golgi vesicle transport	GO:0048193	30	0.010
dendrite development	GO:0016358	115	0.010
regulation of purine nucleotide metabolic process	GO:1900542	169	0.010
sensory system development	GO:0048880	3	0.010
circulatory system process	GO:0003013	197	0.010
myelination	GO:0042552	74	0.010
muscle cell differentiation	GO:0042692	261	0.010
stem cell development	GO:0048864	219	0.010
lipid homeostasis	GO:0055088	63	0.010
regulation of cell cycle process	GO:0010564	160	0.010
adult behavior	GO:0030534	135	0.010

Osbp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.033
disease of anatomical entity	DOID:7	0.021
musculoskeletal system disease	DOID:17	0.021
immune system disease	DOID:2914	0.021
nervous system disease	DOID:863	0.018
cardiovascular system disease	DOID:1287	0.016
connective tissue disease	DOID:65	0.015
inherited metabolic disorder	DOID:655	0.015
muscular disease	DOID:0080000	0.014
myopathy	DOID:423	0.014
muscle tissue disease	DOID:66	0.014
disease of cellular proliferation	DOID:14566	0.014
bone disease	DOID:0080001	0.013
cancer	DOID:162	0.013
organ system cancer	DOID:0050686	0.013
acquired metabolic disease	DOID:0060158	0.012
hematopoietic system disease	DOID:74	0.011
carbohydrate metabolism disease	DOID:0050013	0.011
heart disease	DOID:114	0.011
glucose metabolism disease	DOID:4194	0.010
bone development disease	DOID:0080006	0.010
diabetes mellitus	DOID:9351	0.010

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