Mus musculus

260 known processes

Pitx2

paired-like homeodomain transcription factor 2

(Aliases: Munc30,Otlx2,Pitx2cbeta,Ptx2,Rieg,Brx1b,Pitx2c,Brx1a,Pitx2b,9430085M16Rik,Brx1,Pitx2a)

Pitx2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regionalizationGO:00030023371.000
embryonic skeletal system developmentGO:00487061201.000
Zebrafish
embryonic organ morphogenesisGO:00485622761.000
limb morphogenesisGO:00351081491.000
carbon catabolite repression of transcription from rna polymerase ii promoterGO:000043711.000
determination of heart left right asymmetryGO:0061371481.000
appendage morphogenesisGO:00351071491.000
pyramidal neuron migrationGO:002185211.000
lateral motor column neuron migrationGO:009747731.000
heart morphogenesisGO:00030071781.000
determination of left right symmetryGO:0007368801.000
heart formationGO:0060914161.000
visceral motor neuron differentiationGO:002152431.000
peripheral nervous system neuron axonogenesisGO:004893631.000
cell proliferation in hindbrainGO:0021534101.000
positive regulation of secondary heart field cardioblast proliferationGO:007251341.000
sinoatrial node cell differentiationGO:006092131.000
cardiac cell fate determinationGO:006091321.000
epithelial tube morphogenesisGO:00605623031.000
cardiac chamber morphogenesisGO:0003206931.000
cardiac atrium morphogenesisGO:0003209231.000
forebrain neuron fate commitmentGO:0021877131.000
neural tube closureGO:0001843901.000
embryonic appendage morphogenesisGO:00351131261.000
commitment of neuronal cell to specific neuron type in forebrainGO:002190271.000
motor neuron migrationGO:009747541.000
spinal cord motor neuron migrationGO:009747641.000
embryonic eye morphogenesisGO:0048048291.000
Zebrafish
neural tube developmentGO:00219151601.000
cardiac muscle tissue morphogenesisGO:0055008441.000
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetryGO:190009421.000
endodermal cell fate commitmentGO:0001711121.000
stem cell developmentGO:00488642191.000
embryonic heart tube developmentGO:0035050651.000
Zebrafish
telencephalon developmentGO:00215371861.000
embryonic skeletal system morphogenesisGO:0048704911.000
Zebrafish
endodermal cell fate specificationGO:000171441.000
limb developmentGO:00601731661.000
nephric duct elongationGO:003584911.000
mesenchyme developmentGO:00604851521.000
nodal signaling pathway involved in determination of left right asymmetryGO:003810721.000
cardioblast migration to the midline involved in heart field formationGO:006097511.000
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiationGO:000325731.000
negative regulation of cardiac chamber morphogenesisGO:190122021.000
embryonic heart tube morphogenesisGO:0003143511.000
cardiac septum morphogenesisGO:0060411461.000
muscle tissue developmentGO:00605373081.000
appendage developmentGO:00487361661.000
embryonic viscerocranium morphogenesisGO:004870381.000
Zebrafish
gastrulationGO:00073691161.000
positive regulation of auditory receptor cell differentiationGO:004560911.000
embryonic heart tube left right pattern formationGO:006097151.000
Zebrafish
cardiac neural crest cell migration involved in outflow tract morphogenesisGO:000325331.000
auditory receptor cell fate determinationGO:004266831.000
cardiac atrium developmentGO:0003230241.000
somitogenesisGO:0001756691.000
primary neural tube formationGO:0014020951.000
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formationGO:200080211.000
cardiac ventricle developmentGO:0003231831.000
endocardial cushion morphogenesisGO:0003203181.000
somite rostral caudal axis specificationGO:0032525131.000
left right pattern formationGO:0060972231.000
regulation of apoptotic process involved in outflow tract morphogenesisGO:190225621.000
skeletal muscle cell differentiationGO:0035914661.000
trophectodermal cell differentiationGO:0001829211.000
cell fate specificationGO:0001708721.000
positive regulation of transcription by glucoseGO:004601631.000
atrial septum developmentGO:0003283121.000
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetryGO:190016421.000
mesenchymal cell differentiationGO:00487621071.000
respiratory system developmentGO:00605411901.000
cardiac chamber developmentGO:00032051081.000
muscle tissue morphogenesisGO:0060415531.000
regulation of heart morphogenesisGO:2000826221.000
embryonic heart tube anterior posterior pattern specificationGO:003505431.000
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic processGO:200076311.000
neuron projection guidanceGO:00974851411.000
Worm
metanephric nephron morphogenesisGO:0072273191.000
cerebral cortex neuron differentiationGO:0021895191.000
cardiac septum developmentGO:0003279591.000
carbon catabolite activation of transcription from rna polymerase ii promoterGO:000043641.000
outflow tract septum morphogenesisGO:0003148111.000
spinal cord developmentGO:0021510811.000
horizontal cell localizationGO:003585211.000
striated muscle tissue developmentGO:00147062931.000
renal system developmentGO:00720012251.000
clara cell differentiationGO:006048641.000
midbrain hindbrain boundary morphogenesisGO:002155541.000
metanephros morphogenesisGO:0003338241.000
pituitary gland developmentGO:0021983381.000
heart field specificationGO:000312861.000
notochord formationGO:001402851.000
telencephalon regionalizationGO:0021978141.000
positive regulation of transcription from rna polymerase ii promoter involved in heart developmentGO:190122841.000
specification of organ identityGO:0010092301.000
diencephalon developmentGO:0021536631.000
cell migration involved in gastrulationGO:0042074131.000
atrioventricular bundle cell differentiationGO:000316711.000
hindlimb morphogenesisGO:0035137421.000
regulation of cardioblast proliferationGO:000326491.000
cardioblast migrationGO:000326011.000
regulation of cardiac chamber formationGO:190121011.000
cardiac muscle cell differentiationGO:0055007691.000
regulation of organ morphogenesisGO:20000271441.000
ventricular septum morphogenesisGO:0060412271.000
stem cell differentiationGO:00488632681.000
cardiac ventricle morphogenesisGO:0003208501.000
morphogenesis of a branching structureGO:00017632031.000
left lung morphogenesisGO:006046031.000
cardiac muscle tissue developmentGO:00487381301.000
granulocyte colony stimulating factor productionGO:007161111.000
regulation of organ formationGO:0003156341.000
forebrain neuron differentiationGO:0021879521.000
oviduct epithelium developmentGO:003584611.000
positive regulation of transcription from rna polymerase ii promoter by glucoseGO:000043231.000
regulation of cell proliferation involved in heart morphogenesisGO:2000136151.000
sensory organ morphogenesisGO:00905962421.000
Human Zebrafish Mouse
neuron fate specificationGO:0048665301.000
positive regulation of ureteric bud formationGO:007210731.000
cardiac muscle cell myoblast differentiationGO:006037981.000
skeletal system morphogenesisGO:00487052031.000
Zebrafish
regulation of ureteric bud formationGO:007210631.000
formation of primary germ layerGO:0001704771.000
negative regulation of mesodermal cell fate specificationGO:004266231.000
segmentationGO:0035282931.000
embryonic epithelial tube formationGO:00018381301.000
positive regulation of nephron tubule epithelial cell differentiationGO:200076811.000
positive regulation of macrophage colony stimulating factor productionGO:190125811.000
atrioventricular valve morphogenesisGO:0003181131.000
cell differentiation involved in embryonic placenta developmentGO:0060706261.000
mitral valve morphogenesisGO:000318341.000
cardioblast proliferationGO:000326381.000
planar cell polarity pathway involved in cardiac muscle tissue morphogenesisGO:006135021.000
regulation of nephron tubule epithelial cell differentiationGO:007218291.000
positive regulation of inner ear receptor cell differentiationGO:200098211.000
sinoatrial node developmentGO:000316341.000
organ growthGO:00352651171.000
hindbrain developmentGO:00309021281.000
nephron tubule morphogenesisGO:0072078681.000
neural crest cell developmentGO:0014032481.000
secondary heart field specificationGO:000313960.999
cardiac conduction system developmentGO:0003161120.999
gland developmentGO:00487323300.999
neural tube formationGO:00018411080.999
forebrain generation of neuronsGO:0021872630.999
cerebellar granule cell precursor proliferationGO:0021930100.999
digestive system developmentGO:00551232000.999
positive regulation of branching involved in ureteric bud morphogenesisGO:0090190180.999
atrial septum morphogenesisGO:0060413110.999
cardiocyte differentiationGO:0035051870.999
digestive tract developmentGO:00485651900.999
outflow tract morphogenesisGO:0003151530.999
olfactory lobe developmentGO:0021988320.999
regulation of skeletal muscle fiber differentiationGO:190280930.999
positive regulation of heart growthGO:0060421180.999
ventral spinal cord interneuron specificationGO:0021521110.999
regulation of cardiac chamber morphogenesisGO:190121920.999
forebrain regionalizationGO:0021871250.999
regulation of tongue muscle cell differentiationGO:200103520.999
cell differentiation in spinal cordGO:0021515530.999
endocrine system developmentGO:0035270980.999
embryonic retina morphogenesis in camera type eyeGO:006005970.999
ear morphogenesisGO:00424711180.999
skeletal system developmentGO:00015013560.999
cell proliferation involved in heart morphogenesisGO:0061323150.999
urogenital system developmentGO:00016552610.999
regulation of canonical wnt signaling pathwayGO:0060828820.999
his purkinje system cell differentiationGO:006093220.999
striated muscle cell proliferationGO:0014855390.999
cell fate commitmentGO:00451652100.999
Mouse
mesodermal to mesenchymal transition involved in gastrulationGO:006080910.999
positive regulation of mesenchymal cell proliferation involved in ureter developmentGO:200072930.999
response to fibroblast growth factorGO:0071774470.999
neural crest cell migrationGO:0001755320.999
anterior commissure morphogenesisGO:002196060.999
ventral spinal cord interneuron differentiationGO:0021514160.999
mesenchymal cell developmentGO:0014031930.999
morphogenesis of embryonic epitheliumGO:00163311590.999
Zebrafish
endoderm formationGO:0001706200.999
regulation of cardiac muscle tissue developmentGO:0055024310.999
cochlea morphogenesisGO:0090103220.999
bmp signaling pathwayGO:0030509930.999
neural tube patterningGO:0021532430.999
positive regulation of mesenchymal cell proliferationGO:0002053330.999
regulation of cardiac muscle tissue growthGO:0055021260.999
thyroid stimulating hormone secreting cell differentiationGO:006012940.999
spinal cord motor neuron cell fate specificationGO:0021520130.999
tricuspid valve developmentGO:000317530.999
medial motor column neuron differentiationGO:002152620.999
central nervous system neuron differentiationGO:00219531620.999
epithelial cell differentiation involved in kidney developmentGO:0035850230.999
renal vesicle developmentGO:0072087170.999
ventral spinal cord interneuron fate commitmentGO:0060579140.999
negative regulation of heart loopingGO:190120810.999
positive regulation of cardiac muscle cell proliferationGO:0060045150.999
atrial cardiac muscle cell differentiationGO:005501120.999
blastocyst formationGO:0001825330.999
ventral spinal cord developmentGO:0021517480.999
lung inductionGO:006049230.999
pulmonary valve developmentGO:000317750.999
head morphogenesisGO:0060323340.999
Zebrafish
axial mesodermal cell fate commitmentGO:004832210.999
forebrain morphogenesisGO:0048853170.999
regulation of branching involved in ureteric bud morphogenesisGO:0090189220.999
cardiac chamber formationGO:0003207100.999
trabecular meshwork developmentGO:000293020.999
branching morphogenesis of an epithelial tubeGO:00487541590.999
vagus nerve developmentGO:002156430.999
endocardial cushion to mesenchymal transition involved in heart valve formationGO:000319940.999
embryonic heart tube formationGO:000314410.999
cerebellar purkinje cell granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferationGO:002193760.998
cardiac right atrium morphogenesisGO:000321330.998
regulation of vascular wound healingGO:006104320.998
regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiationGO:000325660.998
forebrain developmentGO:00309003020.998
positive regulation of cardioblast differentiationGO:005189130.998
endocardial cushion formationGO:0003272130.998
positive regulation of epithelial cell proliferation involved in lung morphogenesisGO:006050130.998
renal tubule developmentGO:0061326870.998
neural plate morphogenesisGO:000183990.998
negative regulation of canonical wnt signaling pathway involved in neural plate anterior posterior pattern formationGO:006082910.998
olfactory bulb developmentGO:0021772300.998
positive regulation of epithelial cell differentiation involved in kidney developmentGO:200069820.998
gonad morphogenesisGO:003526210.998
regulation of endocardial cushion to mesenchymal transition involved in heart valve formationGO:200080010.998
hypophysis morphogenesisGO:004885030.998
cerebral cortex developmentGO:0021987860.998
cardiac ventricle formationGO:000321180.998
renal vesicle morphogenesisGO:0072077150.998
ventricular cardiac muscle tissue morphogenesisGO:0055010320.998
positive regulation of transcription via serum response element bindingGO:001073510.998
tongue morphogenesisGO:004358780.998
aorta morphogenesisGO:0035909220.998
specification of organ positionGO:001015930.998
ventricular septum developmentGO:0003281420.998
cell proliferation in forebrainGO:0021846300.998
wnt signaling pathwayGO:00160551880.998
regulation of cerebellar granule cell precursor proliferationGO:0021936120.998
glomerular mesangial cell developmentGO:007214430.998
primitive streak formationGO:0090009100.998
apoptotic process involved in outflow tract morphogenesisGO:000327520.998
heart valve morphogenesisGO:0003179210.997
lung developmentGO:00303241640.997
bundle of his developmentGO:000316640.997
cell proliferation involved in outflow tract morphogenesisGO:006132540.997
regulation of myoblast proliferationGO:200029180.997
cell fate commitment involved in formation of primary germ layerGO:0060795260.997
negative regulation of apoptotic process involved in outflow tract morphogenesisGO:190225720.997
paraxial mesodermal cell differentiationGO:004834220.997
cerebral cortex radially oriented cell migrationGO:0021799310.997
spinal cord association neuron differentiationGO:0021527140.997
somite developmentGO:0061053810.997
odontogenesis of dentin containing toothGO:0042475660.997
Rat
cardiac right ventricle formationGO:000321930.997
embryonic placenta developmentGO:0001892980.997
spinal cord dorsal ventral patterningGO:0021513230.997
primary prostatic bud elongationGO:006051620.997
negative regulation of wnt signaling pathway involved in heart developmentGO:000330840.997
mesoderm developmentGO:00074981000.997
Zebrafish
ventricular cardiac myofibril assemblyGO:005500530.997
regulation of macrophage colony stimulating factor productionGO:190125610.997
cardiac neural crest cell development involved in heart developmentGO:006130870.997
regulation of cardioblast differentiationGO:005189030.997
digestive tract morphogenesisGO:00485461470.997
positive regulation of tongue muscle cell differentiationGO:200103720.997
atrial septum primum morphogenesisGO:000328930.997
tube closureGO:0060606910.997
skeletal muscle organ developmentGO:00605381630.996
regulation of striated muscle cell differentiationGO:0051153810.996
cardiac left ventricle formationGO:000321810.996
morphogenesis of a branching epitheliumGO:00611381930.996
mesenchymal cell proliferation involved in ureter developmentGO:007219840.996
mesenchyme morphogenesisGO:0072132320.996
ureteric bud morphogenesisGO:0060675620.996
heart valve developmentGO:0003170230.996
uterine epithelium developmentGO:003584710.996
mitral valve developmentGO:000317440.996
forelimb morphogenesisGO:0035136400.996
endoderm developmentGO:0007492450.996
Zebrafish
determination of digestive tract left right asymmetryGO:007190710.996
Zebrafish
canonical wnt signaling pathwayGO:00600701300.996
negative regulation of wnt signaling pathwayGO:0030178730.996
s shaped body morphogenesisGO:007205060.996
tendon formationGO:003599240.996
tendon cell differentiationGO:003599040.996
wnt signaling pathway involved in kidney developmentGO:006128920.995
metanephric capsule specificationGO:007226710.995
anterior head developmentGO:009706520.995
myotube cell developmentGO:0014904600.995
mesoderm morphogenesisGO:0048332640.995
regulation of neural retina developmentGO:006107430.995
prostate gland stromal morphogenesisGO:006074120.995
developmental growth involved in morphogenesisGO:00605601380.995
camera type eye developmentGO:00430102660.995
embryonic camera type eye developmentGO:0031076360.995
axon guidanceGO:00074111410.995
Worm
embryonic limb morphogenesisGO:00303261260.995
regulation of endodermal cell differentiationGO:190322420.995
regulation of heart loopingGO:190120710.995
regulation of transcription involved in primary germ layer cell fate commitmentGO:006079620.995
bone morphogenesisGO:0060349780.995
negative regulation of transcription from rna polymerase ii promoter by glucoseGO:000043310.995
positive regulation of cardiac muscle tissue growthGO:0055023150.995
pancreatic a cell fate commitmentGO:000332620.995
face morphogenesisGO:0060325290.995
Zebrafish
somite specificationGO:000175740.995
cardiac muscle cell developmentGO:0055013390.995
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus developmentGO:006052840.995
cell proliferation in external granule layerGO:0021924100.995
mammary placode formationGO:006059640.994
regulation of muscle tissue developmentGO:1901861970.994
cerebellar purkinje cell layer developmentGO:0021680260.994
positive regulation of stem cell proliferationGO:2000648590.994
regulation of myotube differentiationGO:0010830620.994
floor plate morphogenesisGO:003350530.994
regulation of bmp signaling pathwayGO:0030510600.994
pancreatic pp cell fate commitmentGO:000332920.994
spinal cord motor neuron differentiationGO:0021522350.994
ectoderm formationGO:000170530.994
epithelial tube formationGO:00721751300.994
metanephric s shaped body morphogenesisGO:007228420.994
regulation of epithelial cell differentiation involved in kidney developmentGO:2000696100.994
regulation of cell migration involved in sprouting angiogenesisGO:009004940.994
positive regulation of anterior head developmentGO:200074420.994
closure of optic fissureGO:006138620.994
Zebrafish
spinal cord patterningGO:0021511250.994
positive regulation of cardiac muscle tissue developmentGO:0055025190.993
stem cell maintenanceGO:00198271300.993
neuron migrationGO:00017641220.993
planar cell polarity pathway involved in pericardium morphogenesisGO:006135420.993
metanephric nephron tubule formationGO:007228940.993
inner ear receptor cell differentiationGO:0060113610.993
cellular response to fibroblast growth factor stimulusGO:0044344470.993
lens morphogenesis in camera type eyeGO:0002089240.993
Mouse
axis elongation involved in somitogenesisGO:009024540.993
wnt signaling pathway involved in forebrain neuroblast divisionGO:002187420.993
regulation of skeletal muscle fiber developmentGO:0048742360.993
endocardial cushion developmentGO:0003197260.993
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specificationGO:002191340.993
determination of left right asymmetry in nervous systemGO:003554510.993
zygotic determination of anterior posterior axis embryoGO:000735430.992
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.992
prostate gland morphogenesisGO:0060512320.992
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.992
regulation of stem cell proliferationGO:0072091780.992
regulation of secondary heart field cardioblast proliferationGO:000326690.992
regulation of myoblast differentiationGO:0045661290.992
paraxial mesodermal cell fate commitmentGO:004834320.992
regulation of neuron differentiationGO:00456642810.992
hypothalamus developmentGO:0021854160.992
carbon catabolite repression of transcriptionGO:004501310.992
ear developmentGO:00435832000.992
endocardial cell differentiationGO:006095640.991
cell fate determinationGO:0001709320.991
glomerular mesangial cell differentiationGO:007200830.991
regulation of somitogenesisGO:001480760.991
gabaergic neuron differentiationGO:0097154110.991
Worm
positive regulation of skeletal muscle fiber differentiationGO:190281120.991
positive regulation of skeletal muscle tissue regenerationGO:004341540.991
ventricular cardiac muscle tissue developmentGO:0003229380.991
nephron morphogenesisGO:0072028690.990
kidney developmentGO:00018222130.990
mesodermal cell migrationGO:000807840.990
negative regulation of canonical wnt signaling pathwayGO:0090090510.990
regulation of mesodermal cell fate specificationGO:004266150.990
renal capsule specificationGO:007213010.989
retinal ganglion cell axon guidanceGO:0031290180.989
pulmonary valve formationGO:000319310.989
regulation of anterior head developmentGO:200074220.989
macrophage colony stimulating factor productionGO:003630110.989
regulation of cilium assemblyGO:190201770.989
comma shaped body morphogenesisGO:007204950.989
hemangioblast cell differentiationGO:006021710.988
metencephalon developmentGO:0022037890.988
negative regulation of cardiac chamber formationGO:190121110.988
regulation of canonical wnt signaling pathway involved in neural plate anterior posterior pattern formationGO:006082710.988
nephron tubule epithelial cell differentiationGO:0072160110.988
myotube differentiationGO:00149021050.988
axonogenesisGO:00074092740.988
Worm
pancreas developmentGO:0031016570.988
mesonephric tubule morphogenesisGO:0072171630.988
pulmonary valve morphogenesisGO:000318450.988
left right axis specificationGO:0070986130.988
lung epithelial cell differentiationGO:0060487290.988
columnar cuboidal epithelial cell differentiationGO:0002065820.988
coronary vasculature developmentGO:0060976120.987
neural crest cell differentiationGO:0014033540.987
striated muscle cell developmentGO:00550021250.987
sinoatrial node cell developmentGO:006093130.987
gastrulation with mouth forming secondGO:0001702290.987
cardiac right ventricle morphogenesisGO:0003215130.987
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.987
middle ear morphogenesisGO:0042474230.987
mesonephric tubule developmentGO:0072164940.987
regulation of endodermal cell fate specificationGO:004266320.987
cerebral cortex gabaergic interneuron differentiationGO:002189290.987
tube formationGO:00351481400.986
gonad developmentGO:00084061410.986
Rat
renal vesicle inductionGO:007203430.986
embryonic digit morphogenesisGO:0042733560.986
locus ceruleus developmentGO:002170310.986
mesodermal cell fate specificationGO:0007501110.986
metanephric renal vesicle morphogenesisGO:0072283120.986
positive regulation of cerebellar granule cell precursor proliferationGO:0021940100.986
lung cell differentiationGO:0060479300.986
cerebellar cortex formationGO:0021697220.985
intracellular receptor signaling pathwayGO:0030522740.985
Zebrafish
morphogenesis of a polarized epitheliumGO:0001738370.985
cerebral cortex cell migrationGO:0021795440.985
somatic motor neuron differentiationGO:002152360.985
mesoderm formationGO:0001707620.984
negative regulation of embryonic developmentGO:0045992220.984
semaphorin plexin signaling pathway involved in outflow tract morphogenesisGO:007152710.984
positive regulation of striated muscle tissue developmentGO:0045844310.984
cerebral cortex tangential migrationGO:002180070.984
maintenance of apical basal cell polarityGO:003509030.984
carbon catabolite activation of transcriptionGO:004599140.984
pharynx developmentGO:006046510.983
heart valve formationGO:0003188100.983
auditory receptor cell fate specificationGO:004266710.983
nephron epithelium morphogenesisGO:0072088680.982
tongue muscle cell differentiationGO:003598120.982
diencephalon morphogenesisGO:004885260.982
positive regulation of growthGO:00459271040.982
left lung developmentGO:006045940.982
regulation of transcription from rna polymerase ii promoter involved in heart developmentGO:190121390.982
positive regulation of cell migration involved in sprouting angiogenesisGO:009005030.982
deltoid tuberosity developmentGO:003599330.981
coronary vasculature morphogenesisGO:006097790.981
cellular response to growth factor stimulusGO:00713631970.981
branch elongation involved in ureteric bud branchingGO:006068130.981
septum primum developmentGO:000328440.981
megakaryocyte differentiationGO:0030219260.981
muscle cell differentiationGO:00426922610.981
regulation of embryonic developmentGO:0045995710.980
mesodermal cell fate commitmentGO:0001710170.980
embryonic forelimb morphogenesisGO:0035115320.980
aortic valve developmentGO:000317650.980
pericardium developmentGO:0060039160.980
branching involved in mammary gland duct morphogenesisGO:0060444270.980
positive regulation of skeletal muscle cell differentiationGO:200101640.980
midbrain hindbrain boundary maturationGO:002173210.979
nephric duct formationGO:007217940.979
cardiac pacemaker cell developmentGO:006092650.979
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formationGO:006082310.979
cardiac endothelial cell differentiationGO:000334840.978
ventral midline developmentGO:000741840.977
paramesonephric duct developmentGO:006120530.977
regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formationGO:200070210.977
carbon catabolite regulation of transcription from rna polymerase ii promoterGO:000042940.977
cell migration to the midline involved in heart developmentGO:000331810.976
respiratory tube developmentGO:00303231670.976
astrocyte fate commitmentGO:006001840.976
muscle cell developmentGO:00550011330.975
placenta developmentGO:00018901400.975
enamel mineralizationGO:007016670.975
epithelial mesenchymal signaling involved in prostate gland developmentGO:006073820.975
cardiac cell fate commitmentGO:0060911100.974
negative regulation of neuron projection developmentGO:0010977500.974
neuron fate determinationGO:004866490.974
heart growthGO:0060419450.974
his purkinje system developmentGO:000316440.973
cell differentiation in hindbrainGO:0021533240.973
negative regulation of neuron differentiationGO:00456651010.973
bone developmentGO:00603481200.972
carbon catabolite regulation of transcriptionGO:004599040.972
lung morphogenesisGO:0060425500.972
glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formationGO:200070110.972
kidney epithelium developmentGO:00720731210.972
epithelial to mesenchymal transition involved in endocardial cushion formationGO:0003198100.972
regulation of wnt signaling pathwayGO:00301111230.971
skeletal muscle fiber developmentGO:0048741580.971
atrial ventricular junction remodelingGO:000329420.971
negative regulation of gastrulationGO:200054230.971
globus pallidus developmentGO:002175920.971
noradrenergic neuron differentiationGO:000335760.971
cerebral cortex gabaergic interneuron migrationGO:002185360.971
negative regulation of transcription by glucoseGO:004501410.970
venous blood vessel morphogenesisGO:004884570.970
brain morphogenesisGO:0048854320.970
ameboidal type cell migrationGO:00016671280.970
regulation of cardiac muscle cell proliferationGO:0060043230.970
mesodermal cell differentiationGO:0048333220.969
aortic valve morphogenesisGO:000318040.969
forebrain anterior posterior pattern specificationGO:002179750.969
endodermal cell fate determinationGO:000749320.969
tongue developmentGO:0043586180.968
semicircular canal morphogenesisGO:004875270.968
myoblast proliferationGO:0051450110.967
epithelial cell maturation involved in prostate gland developmentGO:006074340.966
cell differentiation involved in kidney developmentGO:0061005330.966
body morphogenesisGO:0010171450.966
Zebrafish
cerebellar purkinje cell differentiationGO:0021702130.966
eye photoreceptor cell developmentGO:0042462310.966
liver developmentGO:0001889660.965
transcriptional activation by promoter enhancer loopingGO:007173320.965

Pitx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.996
musculoskeletal system diseaseDOID:1700.996
cardiovascular system diseaseDOID:128700.969