IMP: Integrative Multi-species Prediction

Mus musculus

39 known processes

Plrg1

pleiotropic regulator 1, PRL1 homolog (Arabidopsis)

(Aliases: AA958940,C80566)

Entrez: 53317
Ensembl: ENSMUSG00000027998
UniProtKB: Q922V4

Process Predictions
Disease Predictions

Plrg1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
rna processing	GO:0006396	105	0.314	Yeast
toxin transport	GO:1901998	38	0.264
rna splicing	GO:0008380	54	0.222	Yeast
ribosomal small subunit biogenesis	GO:0042274	4	0.200
fertilization	GO:0009566	127	0.197
nucleoside monophosphate catabolic process	GO:0009125	59	0.175
mrna processing	GO:0006397	63	0.172	Yeast
atp catabolic process	GO:0006200	55	0.137
ribonucleoside catabolic process	GO:0042454	206	0.116
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045899	2	0.116
microtubule cytoskeleton organization involved in mitosis	GO:1902850	4	0.115
organonitrogen compound catabolic process	GO:1901565	264	0.114
endocytosis	GO:0006897	168	0.109
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.108
rna splicing via transesterification reactions	GO:0000375	43	0.106	Yeast
positive regulation of transcription elongation from rna polymerase ii promoter	GO:0032968	2	0.104
gonad development	GO:0008406	141	0.103
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.099
cellular nitrogen compound catabolic process	GO:0044270	280	0.097
purine nucleotide metabolic process	GO:0006163	302	0.088
modification dependent protein catabolic process	GO:0019941	133	0.087
single fertilization	GO:0007338	82	0.087
germ cell development	GO:0007281	185	0.083
maternal determination of anterior posterior axis embryo	GO:0008358	2	0.081
development of primary sexual characteristics	GO:0045137	143	0.079
molting cycle	GO:0042303	90	0.078	Worm
purine nucleoside monophosphate catabolic process	GO:0009128	58	0.077
terminal button organization	GO:0072553	3	0.069
spindle assembly involved in mitosis	GO:0090307	4	0.069
mechanosensory behavior	GO:0007638	6	0.068
positive regulation of dna templated transcription elongation	GO:0032786	2	0.067
stem cell differentiation	GO:0048863	268	0.067
oocyte anterior posterior axis specification	GO:0007314	2	0.067
microtubule based process	GO:0007017	236	0.066
blastocyst development	GO:0001824	80	0.066
oocyte axis specification	GO:0007309	2	0.065
purine ribonucleotide metabolic process	GO:0009150	290	0.060
intracellular mrna localization	GO:0008298	4	0.060
purine nucleotide catabolic process	GO:0006195	211	0.054
pole plasm assembly	GO:0007315	2	0.051
mitotic nuclear division	GO:0007067	48	0.048
nucleoside phosphate catabolic process	GO:1901292	222	0.047
modification dependent macromolecule catabolic process	GO:0043632	133	0.047
regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045898	2	0.046
protein localization to nucleus	GO:0034504	121	0.044
microtubule cytoskeleton organization	GO:0000226	157	0.043
ribonucleoside monophosphate catabolic process	GO:0009158	57	0.043
purine containing compound metabolic process	GO:0072521	311	0.042
cellular response to dna damage stimulus	GO:0006974	207	0.042	Zebrafish
cardiac endothelial cell differentiation	GO:0003348	4	0.042
developmental maturation	GO:0021700	193	0.042
trna wobble base modification	GO:0002097	2	0.041
regulation of organelle organization	GO:0033043	289	0.040
purine containing compound catabolic process	GO:0072523	213	0.040
ncrna processing	GO:0034470	26	0.039
purine ribonucleotide catabolic process	GO:0009154	208	0.039
ribonucleotide catabolic process	GO:0009261	208	0.039
mrna metabolic process	GO:0016071	84	0.039	Yeast
genitalia development	GO:0048806	37	0.038
nucleoside monophosphate metabolic process	GO:0009123	85	0.035
purine ribonucleoside metabolic process	GO:0046128	241	0.035
ribonucleotide metabolic process	GO:0009259	291	0.035
organic cyclic compound catabolic process	GO:1901361	295	0.034
purine ribonucleoside monophosphate catabolic process	GO:0009169	57	0.033
protein modification by small protein conjugation or removal	GO:0070647	207	0.032
ribonucleoside monophosphate metabolic process	GO:0009161	80	0.032
regulation of rna splicing	GO:0043484	37	0.031
regulation of protein targeting	GO:1903533	61	0.030
cation transmembrane transport	GO:0098655	266	0.030
oogenesis	GO:0048477	56	0.030
nucleotide catabolic process	GO:0009166	217	0.030
oocyte development	GO:0048599	33	0.030
skeletal system development	GO:0001501	356	0.030
protein import into nucleus	GO:0006606	95	0.030
nucleoside triphosphate metabolic process	GO:0009141	230	0.029
cell maturation	GO:0048469	127	0.028
protein folding	GO:0006457	28	0.028
nucleic acid transport	GO:0050657	18	0.027
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna	GO:0000462	1	0.027
ribose phosphate metabolic process	GO:0019693	291	0.027
nuclear transcribed mrna catabolic process nonsense mediated decay	GO:0000184	1	0.026
organophosphate catabolic process	GO:0046434	232	0.026
purine ribonucleoside catabolic process	GO:0046130	205	0.026
segmentation	GO:0035282	93	0.026
cellular amino acid metabolic process	GO:0006520	103	0.025
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.025
nucleoside catabolic process	GO:0009164	206	0.025
nucleoside metabolic process	GO:0009116	246	0.025
purine nucleoside catabolic process	GO:0006152	205	0.025
rrna processing	GO:0006364	10	0.024
oocyte differentiation	GO:0009994	35	0.024
regulation of cellular component biogenesis	GO:0044087	181	0.024
aromatic compound catabolic process	GO:0019439	286	0.024
cellular macromolecule catabolic process	GO:0044265	206	0.024
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.024
nucleoside phosphate metabolic process	GO:0006753	338	0.024
translesion synthesis	GO:0019985	1	0.024
synapse organization	GO:0050808	125	0.023
positive regulation of cellular catabolic process	GO:0031331	148	0.023
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.023
purine ribonucleoside monophosphate metabolic process	GO:0009167	80	0.023
regulation of cell division	GO:0051302	76	0.022
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.022
cytoplasmic transport	GO:0016482	234	0.022
cellular ketone metabolic process	GO:0042180	84	0.022
regulation of cellular amine metabolic process	GO:0033238	20	0.022
oocyte construction	GO:0007308	2	0.021
hematopoietic progenitor cell differentiation	GO:0002244	143	0.021
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.021
mitotic cell cycle	GO:0000278	195	0.021
nodal signaling pathway involved in determination of left right asymmetry	GO:0038107	2	0.021
purine nucleoside monophosphate metabolic process	GO:0009126	81	0.021
hematopoietic stem cell differentiation	GO:0060218	8	0.020
carbohydrate derivative catabolic process	GO:1901136	231	0.019
protein modification by small protein conjugation	GO:0032446	187	0.019
nucleotide metabolic process	GO:0009117	332	0.019
ras protein signal transduction	GO:0007265	77	0.019
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.019
mrna splicing via spliceosome	GO:0000398	43	0.019	Yeast
methylation	GO:0032259	134	0.018
heterocycle catabolic process	GO:0046700	280	0.018
inorganic ion transmembrane transport	GO:0098660	234	0.018
atp metabolic process	GO:0046034	75	0.018
single organism nuclear import	GO:1902593	95	0.017
digestive system development	GO:0055123	200	0.017
protein localization to organelle	GO:0033365	185	0.017
macromolecule catabolic process	GO:0009057	281	0.017
nuclear transport	GO:0051169	139	0.017
amine metabolic process	GO:0009308	45	0.016
cellular protein catabolic process	GO:0044257	155	0.016
organelle fission	GO:0048285	170	0.016
purine nucleoside metabolic process	GO:0042278	241	0.016
regulation of cellular ketone metabolic process	GO:0010565	66	0.016
interspecies interaction between organisms	GO:0044419	83	0.016
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.016
positive regulation of protein catabolic process	GO:0045732	60	0.016
positive regulation of cellular amine metabolic process	GO:0033240	5	0.016
protein import	GO:0017038	101	0.016
ribonucleoside metabolic process	GO:0009119	245	0.015
nuclear import	GO:0051170	95	0.015
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.015
rna localization	GO:0006403	23	0.015
regulation of cellular amino acid metabolic process	GO:0006521	5	0.015
apoptotic signaling pathway	GO:0097190	306	0.015
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	88	0.015
positive regulation of hydrolase activity	GO:0051345	148	0.014
glycosyl compound catabolic process	GO:1901658	206	0.014
male gamete generation	GO:0048232	285	0.014
intracellular protein transport	GO:0006886	204	0.014
ribosome biogenesis	GO:0042254	20	0.014
response to acid chemical	GO:0001101	111	0.014
regulation of intracellular transport	GO:0032386	159	0.013
response to granulocyte macrophage colony stimulating factor	GO:0097012	3	0.013
organelle assembly	GO:0070925	177	0.013
peptidyl amino acid modification	GO:0018193	336	0.013
regionalization	GO:0003002	337	0.013
trna wobble uridine modification	GO:0002098	2	0.013
spermatogenesis	GO:0007283	284	0.013
inorganic cation transmembrane transport	GO:0098662	207	0.013
regulation of chromosome organization	GO:0033044	83	0.013
regulation of mrna splicing via spliceosome	GO:0048024	32	0.013
neuromuscular synaptic transmission	GO:0007274	16	0.013
negative regulation of molecular function	GO:0044092	258	0.012
sperm egg recognition	GO:0035036	37	0.012
nucleobase containing small molecule metabolic process	GO:0055086	352	0.012
rna polymerase ii transcriptional preinitiation complex assembly	GO:0051123	3	0.012
dna templated transcriptional preinitiation complex assembly	GO:0070897	4	0.012
cellular amine metabolic process	GO:0044106	44	0.012
maturation of ssu rrna	GO:0030490	1	0.012
regulation of multi organism process	GO:0043900	111	0.012
cell division	GO:0051301	120	0.012
snorna metabolic process	GO:0016074	1	0.012
positive regulation of atp catabolic process	GO:1903291	3	0.012
regulation of nucleotide metabolic process	GO:0006140	169	0.011
regulation of nuclear division	GO:0051783	56	0.011
nuclear division	GO:0000280	158	0.011
female gamete generation	GO:0007292	74	0.011
nucleus organization	GO:0006997	45	0.011
protein modification by small protein removal	GO:0070646	21	0.011
trna metabolic process	GO:0006399	11	0.011
nucleic acid phosphodiester bond hydrolysis	GO:0090305	49	0.011
small gtpase mediated signal transduction	GO:0007264	97	0.011
proteasomal protein catabolic process	GO:0010498	98	0.011
synaptic transmission	GO:0007268	329	0.011
nucleocytoplasmic transport	GO:0006913	139	0.011
regulation of dna templated transcription elongation	GO:0032784	10	0.011
nucleoside triphosphate catabolic process	GO:0009143	205	0.011
regulation of protein complex assembly	GO:0043254	83	0.010
receptor mediated endocytosis	GO:0006898	51	0.010
divalent inorganic cation transport	GO:0072511	178	0.010
trna processing	GO:0008033	11	0.010
cell cell recognition	GO:0009988	44	0.010
rrna metabolic process	GO:0016072	10	0.010

Plrg1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.016
nervous system disease	DOID:863	0.016
eye and adnexa disease	DOID:1492	0.010
retinal disease	DOID:5679	0.010
sensory system disease	DOID:0050155	0.010
eye disease	DOID:5614	0.010

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