Mus musculus

223 known processes

Ppargc1a

peroxisome proliferative activated receptor, gamma, coactivator 1 alpha

(Aliases: Pgc-1alpha,Pgco1,Pgc1,PGC-1,Ppargc1,PGC-1v,A830037N07Rik)

Ppargc1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of fatty acid metabolic processGO:0019217280.920
Rat
oxidation reduction processGO:00551143420.905
circadian regulation of gene expressionGO:0032922480.901
regulation of fatty acid oxidationGO:0046320100.899
Rat
negative regulation of cellular amine metabolic processGO:003323910.843
intracellular receptor signaling pathwayGO:0030522740.782
monocarboxylic acid metabolic processGO:00327871910.733
Rat
dephosphorylationGO:00163111290.730
Mouse
response to oxidative stressGO:00069791230.686
cellular response to oxidative stressGO:0034599760.671
fatty acid metabolic processGO:00066311210.626
Rat
lipid catabolic processGO:0016042690.622
regulation of cellular amine metabolic processGO:0033238200.616
positive regulation of mitochondrion organizationGO:0010822170.612
striated muscle tissue developmentGO:00147062930.581
negative regulation of fatty acid metabolic processGO:0045922100.566
regulation of circadian rhythmGO:0042752580.543
positive regulation of phosphatase activityGO:001092240.540
Mouse
energy derivation by oxidation of organic compoundsGO:0015980770.539
cellular metal ion homeostasisGO:00068751510.536
cellular response to organonitrogen compoundGO:00714171450.532
lipid modificationGO:0030258650.532
Rat
circadian rhythmGO:00076231140.520
regulation of mitochondrion organizationGO:0010821270.519
amine metabolic processGO:0009308450.513
response to reactive oxygen speciesGO:0000302560.505
Mouse
negative regulation of phosphorylationGO:00423261660.504
inorganic cation transmembrane transportGO:00986622070.502
nucleobase containing small molecule metabolic processGO:00550863520.483
regulation of fatty acid beta oxidationGO:003199810.471
positive regulation of cellular respirationGO:190185730.464
acylglycerol metabolic processGO:0006639550.460
lipid oxidationGO:0034440290.459
Rat
cellular divalent inorganic cation homeostasisGO:00725031270.458
white fat cell differentiationGO:0050872150.457
negative regulation of cellular amino acid metabolic processGO:004576300.446
myeloid cell differentiationGO:00300992330.443
Mouse
lipid homeostasisGO:0055088630.442
hexose metabolic processGO:0019318980.440
Rat
skeletal system developmentGO:00015013560.434
Mouse
muscle tissue developmentGO:00605373080.423
carbohydrate metabolic processGO:00059752300.417
Rat
cellular calcium ion homeostasisGO:00068741190.415
monocarboxylic acid catabolic processGO:0072329270.406
intracellular steroid hormone receptor signaling pathwayGO:0030518290.399
purine ribonucleoside metabolic processGO:00461282410.382
purine nucleoside metabolic processGO:00422782410.381
monosaccharide metabolic processGO:00059961060.367
Rat
organ growthGO:00352651170.366
cation transmembrane transportGO:00986552660.354
regulation of myeloid cell differentiationGO:0045637960.347
Mouse
response to organic cyclic compoundGO:00140701980.341
Rat
cation homeostasisGO:00550802120.333
nucleoside monophosphate metabolic processGO:0009123850.333
rhythmic processGO:00485111740.328
regulation of ion homeostasisGO:2000021640.322
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.321
cytosolic calcium ion homeostasisGO:0051480700.320
cell proliferation in hindbrainGO:0021534100.313
regulation of organ morphogenesisGO:20000271440.312
regulation of cellular ketone metabolic processGO:0010565660.310
Rat
negative regulation of peptidyl serine phosphorylationGO:0033137100.307
cholesterol storageGO:001087840.305
cellular ketone metabolic processGO:0042180840.304
Rat
cellular chemical homeostasisGO:00550822150.304
dna metabolic processGO:00062593030.298
regulation of blood pressureGO:0008217930.296
ion transmembrane transportGO:00342203610.293
Rat
response to alkaloidGO:0043279340.292
ribonucleotide metabolic processGO:00092592910.288
regulation of protein kinase activityGO:00458592320.288
cation transportGO:00068123990.284
forebrain developmentGO:00309003020.281
cellular amine metabolic processGO:0044106440.280
maintenance of locationGO:0051235890.280
tissue remodelingGO:00487711020.278
Mouse
regulation of kinase activityGO:00435492490.277
regulation of sequence specific dna binding transcription factor activityGO:00510901060.273
regulation of atp metabolic processGO:1903578170.271
small molecule catabolic processGO:0044282710.270
positive regulation of atp biosynthetic processGO:200117120.268
regulation of monooxygenase activityGO:003276870.268
negative regulation of protein modification processGO:00314001630.267
metal ion homeostasisGO:00550651890.267
positive regulation of fatty acid oxidationGO:004632140.267
Rat
lipid biosynthetic processGO:00086101790.266
cellular ion homeostasisGO:00068731650.262
calcium ion homeostasisGO:00550741270.258
muscle contractionGO:00069361010.258
ribose phosphate biosynthetic processGO:0046390590.255
regulation of cellular amino acid metabolic processGO:000652150.254
cerebral cortex developmentGO:0021987860.254
asymmetric stem cell divisionGO:009872230.250
lipid transportGO:0006869980.247
purine ribonucleotide metabolic processGO:00091502900.247
positive regulation of mapk cascadeGO:00434101700.242
positive regulation of kinase activityGO:00336741550.242
cholesterol homeostasisGO:0042632440.238
divalent inorganic cation transportGO:00725111780.238
atp metabolic processGO:0046034750.238
gland developmentGO:00487323300.237
blood circulationGO:00080151950.235
organophosphate biosynthetic processGO:00904071220.232
regulation of glucose metabolic processGO:0010906600.231
regulation of mapk cascadeGO:00434082480.230
purine containing compound biosynthetic processGO:0072522700.230
positive regulation of tissue remodelingGO:0034105190.229
Mouse
nucleotide metabolic processGO:00091173320.228
negative regulation of phosphate metabolic processGO:00459361840.227
actin cytoskeleton organizationGO:00300362200.227
Mouse
response to purine containing compoundGO:0014074280.225
neutral lipid metabolic processGO:0006638570.224
generation of precursor metabolites and energyGO:00060911030.224
asymmetric neuroblast divisionGO:005505910.222
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.220
male gamete generationGO:00482322850.220
lipid localizationGO:00108761260.218
purine ribonucleoside triphosphate metabolic processGO:00092052200.216
purine nucleotide biosynthetic processGO:0006164650.215
regulation of fibroblast proliferationGO:0048145340.215
glycerolipid metabolic processGO:00464861220.213
peptidyl amino acid modificationGO:00181933360.206
negative regulation of blood pressureGO:0045776220.206
anion transportGO:00068201770.206
cellular lipid catabolic processGO:0044242520.206
telomere maintenance via telomeraseGO:000700410.204
response to organonitrogen compoundGO:00102432460.199
Rat
regulation of leukocyte differentiationGO:19021051590.199
Mouse
cellular response to hormone stimulusGO:00328701500.197
Rat
regulation of androgen receptor signaling pathwayGO:006076530.193
placenta developmentGO:00018901400.191
sensory organ morphogenesisGO:00905962420.191
response to nutrient levelsGO:00316671090.188
Rat
cognitionGO:00508901490.188
regulation of neurotrophin trk receptor signaling pathwayGO:005138640.188
positive regulation of cell developmentGO:00107202370.186
ribonucleotide biosynthetic processGO:0009260590.185
regulation of nitrogen cycle metabolic processGO:190331410.184
negative regulation of molecular functionGO:00440922580.184
Rat
bone resorptionGO:0045453380.182
Mouse
negative regulation of protein phosphorylationGO:00019331260.181
cerebellar granule cell precursor proliferationGO:0021930100.180
negative regulation of protein metabolic processGO:00512482820.178
regulation of transferase activityGO:00513382630.177
regulation of vitamin d biosynthetic processGO:006055610.173
urogenital system developmentGO:00016552610.172
inorganic ion transmembrane transportGO:00986602340.169
mapk cascadeGO:00001652810.168
heterocycle catabolic processGO:00467002800.162
positive regulation of apoptotic process involved in mammary gland involutionGO:006005840.159
female sex differentiationGO:0046660840.158
inflammatory responseGO:00069542440.155
regulation of voltage gated calcium channel activityGO:190138540.153
positive regulation of protein serine threonine kinase activityGO:00719021060.152
glucose metabolic processGO:0006006920.150
positive regulation of macroautophagyGO:001623930.147
regulation of feeding behaviorGO:006025930.145
cholesterol transportGO:0030301380.145
positive regulation of insulin receptor signaling pathwayGO:004662840.144
positive regulation of protein kinase activityGO:00458601440.144
heart morphogenesisGO:00030071780.142
cellular homeostasisGO:00197252400.142
fatty acid biosynthetic processGO:0006633410.140
triglyceride homeostasisGO:0070328150.139
positive regulation of sodium ion transportGO:0010765130.139
sterol homeostasisGO:0055092450.139
positive regulation of dephosphorylationGO:003530660.138
Mouse
negative regulation of cellular protein metabolic processGO:00322692470.138
fatty acid catabolic processGO:0009062250.138
negative regulation of neuron deathGO:1901215980.136
cellular amino acid metabolic processGO:00065201030.136
cytosolic calcium ion transportGO:0060401480.136
single organism nuclear importGO:1902593950.136
cellular protein catabolic processGO:00442571550.135
cellular macromolecule catabolic processGO:00442652060.135
multicellular organismal homeostasisGO:00488711640.135
regulation of carbohydrate metabolic processGO:0006109750.134
Rat
heart contractionGO:0060047930.134
cellular nitrogen compound catabolic processGO:00442702800.133
regulation of neuron differentiationGO:00456642810.131
branching involved in mammary gland duct morphogenesisGO:0060444270.131
regulation of lipid metabolic processGO:00192161180.129
Rat
regulation of cellular response to growth factor stimulusGO:0090287820.129
purine containing compound metabolic processGO:00725213110.128
negative regulation of cell proliferationGO:00082852960.128
proteolysis involved in cellular protein catabolic processGO:00516031470.126
triglyceride metabolic processGO:0006641510.126
regulation of apoptotic signaling pathwayGO:20012331970.126
steroid metabolic processGO:00082021190.123
Rat
positive regulation of protein modification processGO:00314012990.123
cardiocyte differentiationGO:0035051870.123
regulation of lipid catabolic processGO:0050994150.123
negative regulation of lipid metabolic processGO:0045833300.121
negative regulation of phosphorus metabolic processGO:00105631840.117
nucleoside phosphate biosynthetic processGO:1901293790.116
fat cell differentiationGO:00454441600.116
alpha amino acid metabolic processGO:1901605590.116
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathwayGO:005148240.116
nucleoside biosynthetic processGO:0009163210.116
cellular lipid metabolic processGO:00442553230.116
Rat
positive regulation of programmed cell deathGO:00430682180.116
transmembrane transportGO:00550854120.115
Rat
protein localization to organelleGO:00333651850.115
cell fate commitmentGO:00451652100.115
regulation of sterol transportGO:0032371170.115
hexose biosynthetic processGO:0019319390.115
positive regulation of cell deathGO:00109422240.114
ear developmentGO:00435832000.114
regulation of peptide transportGO:0090087910.113
amide transportGO:00428861380.113
cytoplasmic transportGO:00164822340.111
bone remodelingGO:0046849530.111
Mouse
striated muscle contractionGO:0006941450.111
regulation of ion transmembrane transporter activityGO:0032412540.110
Rat
cellular carbohydrate metabolic processGO:00442621190.110
Rat
intrinsic apoptotic signaling pathway in response to osmotic stressGO:000862720.110
glycosyl compound metabolic processGO:19016572460.109
cardiac muscle tissue developmentGO:00487381300.109
lipoprotein transportGO:004295370.109
organic acid transportGO:00158491010.108
organic hydroxy compound transportGO:0015850930.108
small molecule biosynthetic processGO:00442831320.108
g protein coupled receptor signaling pathwayGO:00071862430.107
response to campGO:0051591140.107
negative regulation of growthGO:0045926990.107
purine ribonucleotide biosynthetic processGO:0009152590.106
prostate gland developmentGO:0030850480.106
organonitrogen compound biosynthetic processGO:19015661920.106
carboxylic acid biosynthetic processGO:0046394860.105
sodium ion transmembrane transportGO:0035725490.105
sodium ion transportGO:0006814730.105
sodium ion importGO:009736910.103
skeletal system morphogenesisGO:00487052030.103
Mouse
regulation of bone remodelingGO:0046850280.102
Mouse
tissue homeostasisGO:00018941150.102
Mouse
regulation of homeostatic processGO:00328441820.102
purine ribonucleoside biosynthetic processGO:0046129190.101
ribonucleoside monophosphate biosynthetic processGO:000915690.100
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.100
positive regulation of gluconeogenesisGO:0045722110.100
purine nucleoside biosynthetic processGO:0042451190.099
branching morphogenesis of an epithelial tubeGO:00487541590.098
sa node cell to atrial cardiac muscle cell signallingGO:008601840.097
sterol transportGO:0015918380.097
epithelial tube morphogenesisGO:00605623030.096
reactive nitrogen species metabolic processGO:200105700.095
membrane biogenesisGO:0044091120.094
ribonucleoside biosynthetic processGO:0042455210.094
regulation of osteoclast differentiationGO:0045670360.094
Mouse
carboxylic acid catabolic processGO:0046395510.094
regulation of relaxation of muscleGO:190107780.093
negative regulation of hormone secretionGO:0046888200.092
negative regulation of tyrosine phosphorylation of stat proteinGO:004253230.092
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.092
multicellular organismal signalingGO:0035637910.091
positive regulation of nucleotide biosynthetic processGO:0030810260.091
regulation of dephosphorylationGO:0035303180.091
Mouse
rna dependent dna replicationGO:000627830.090
regulation of secretion by cellGO:19035302490.090
muscle system processGO:00030121410.090
negative regulation of fat cell differentiationGO:0045599360.090
organonitrogen compound catabolic processGO:19015652640.089
regulation of renal output by angiotensinGO:000201920.087
positive regulation of cytosolic calcium ion concentrationGO:0007204650.087
regulation of glutamine family amino acid metabolic processGO:000082010.087
positive regulation of lipid metabolic processGO:0045834400.086
Rat
telencephalon developmentGO:00215371860.086
regulation of intrinsic apoptotic signaling pathway by p53 class mediatorGO:1902253130.085
regulation of secretionGO:00510462740.084
negative regulation of systemic arterial blood pressureGO:0003085150.084
organic anion transportGO:00157111370.084
regulation of muscle system processGO:0090257800.084
regulation of ion transportGO:00432692150.084
Rat
muscle cell differentiationGO:00426922610.083
purine ribonucleotide catabolic processGO:00091542080.083
ubiquitin dependent protein catabolic processGO:00065111290.083
nucleoside metabolic processGO:00091162460.083
organic acid catabolic processGO:0016054510.082
ribose phosphate metabolic processGO:00196932910.082
regulation of protein serine threonine kinase activityGO:00719001570.081
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediatorGO:190223810.081
neuron migrationGO:00017641220.080
calcium ion transportGO:00068161590.080
cellular response to nutrient levelsGO:0031669640.080
regulation of endothelial cell proliferationGO:0001936230.080
peptide secretionGO:00027901140.080
regulation of heart contractionGO:0008016770.079
fibroblast proliferationGO:0048144350.079
mammary gland lobule developmentGO:0061377220.079
feeding behaviorGO:0007631620.078
positive regulation of apoptotic signaling pathwayGO:2001235950.077
response to organophosphorusGO:0046683220.077
response to steroid hormoneGO:0048545560.077
actin filament organizationGO:00070151130.076
Mouse
negative regulation of neurotrophin trk receptor signaling pathwayGO:005138720.076
mitochondrial dna metabolic processGO:0032042130.076
response to extracellular stimulusGO:00099911270.076
Rat
ammonia assimilation cycleGO:001967620.076
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.075
response to radiationGO:00093141650.074
negative regulation of apoptotic signaling pathwayGO:20012341040.074
response to light stimulusGO:00094161350.074
morphogenesis of a branching structureGO:00017632030.074
cellular response to starvationGO:0009267570.074
negative regulation of fatty acid oxidationGO:004632250.073
regulation of epithelial cell proliferationGO:00506781410.073
cellular response to organic cyclic compoundGO:0071407870.073
regulation of atp biosynthetic processGO:200116930.073
negative regulation of cellular response to growth factor stimulusGO:0090288460.072
glycosyl compound biosynthetic processGO:1901659210.072
positive regulation of transferase activityGO:00513471670.072
regulation of response to woundingGO:19030341890.072
apoptotic process involved in morphogenesisGO:0060561250.071
carbohydrate biosynthetic processGO:0016051740.071
fatty acid beta oxidationGO:0006635160.071
purine nucleotide catabolic processGO:00061952110.071
negative regulation of androgen receptor signaling pathwayGO:006076630.071
chromatin organizationGO:00063252060.071
positive regulation of sodium ion transmembrane transportGO:190230740.070
positive regulation of ion transportGO:0043270650.070
regulation of tissue remodelingGO:0034103380.070
Mouse
reactive oxygen species biosynthetic processGO:190340980.070
organic acid biosynthetic processGO:0016053860.069
trophectodermal cellular morphogenesisGO:000183130.068
lipid storageGO:0019915360.068
cellular response to prostaglandin stimulusGO:007137920.068
nucleocytoplasmic transportGO:00069131390.067
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediatorGO:199012710.067
regulation of hormone secretionGO:0046883880.067
intracellular protein transportGO:00068862040.067
positive regulation of protein phosphorylationGO:00019342420.066
nitrogen compound transportGO:00717052710.066
sequestering of triglycerideGO:003073060.066
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.066
cellular response to lipidGO:00713961450.066
Rat
nucleoside triphosphate metabolic processGO:00091412300.066
muscle cell proliferationGO:0033002520.065
Rat
ossificationGO:00015032160.065
Mouse
peptidyl serine modificationGO:0018209830.065
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.065
regulation of protein localizationGO:00328802310.064
male sex differentiationGO:00466611090.064
monocarboxylic acid biosynthetic processGO:0072330610.063
calcium ion transmembrane transportGO:0070588850.063
directional locomotionGO:003305830.063
cerebellum developmentGO:0021549770.063
macromolecule catabolic processGO:00090572810.063
negative regulation of ion transportGO:0043271280.063
positive regulation of cholesterol transportGO:003237690.063
cellular response to peptide hormone stimulusGO:0071375920.063
peptide hormone secretionGO:00300721090.063
regulation of vitamin metabolic processGO:003065630.063
hippocampus developmentGO:0021766520.063
regionalizationGO:00030023370.063
embryonic placenta developmentGO:0001892980.062
regulation of organelle organizationGO:00330432890.062
regulation of blood circulationGO:1903522930.062
regulation of protein transportGO:00512231630.062
protein targetingGO:00066051430.062
response to oxygen levelsGO:0070482620.061
Rat
glutamate metabolic processGO:000653690.060
male genitalia morphogenesisGO:004880840.060
neuron apoptotic processGO:00514021420.060
regulation of peptide secretionGO:0002791770.060
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.060
sa node cell action potentialGO:008601540.059
cellular potassium ion transportGO:0071804430.059
regulation of carbohydrate biosynthetic processGO:0043255400.058
positive regulation of ion transmembrane transportGO:0034767240.058
glutamine family amino acid metabolic processGO:0009064150.057
positive regulation of nervous system developmentGO:00519622210.057
mammary gland morphogenesisGO:0060443540.057
carboxylic acid transportGO:00469421000.057
male anatomical structure morphogenesisGO:009059840.057
acylglycerol homeostasisGO:0055090160.057
positive regulation of mhc class ii biosynthetic processGO:004534840.056
negative regulation of epithelial cell proliferationGO:0050680640.056
maternal process involved in female pregnancyGO:0060135320.056
positive regulation of calcium ion transportGO:0051928270.056
regulation of ion transmembrane transportGO:00347651190.056
Rat
positive regulation of myeloid leukocyte differentiationGO:0002763260.056
Mouse
receptor biosynthetic processGO:003280030.055
positive regulation of hydrolase activityGO:00513451480.055
Mouse
aromatic compound catabolic processGO:00194392860.055
protein localization to nucleusGO:00345041210.055
regulation of muscle tissue developmentGO:1901861970.054
renal system developmentGO:00720012250.054
glucose homeostasisGO:00425931280.054
spermatogenesisGO:00072832840.054
leukocyte differentiationGO:00025213420.054
Mouse
cell proliferation in external granule layerGO:0021924100.053
positive regulation of neuron differentiationGO:00456661410.053
positive regulation of erk1 and erk2 cascadeGO:0070374470.053
regulation of erk1 and erk2 cascadeGO:0070372710.053
regulation of gluconeogenesisGO:0006111300.053
apoptotic signaling pathwayGO:00971903060.053
regulation of morphogenesis of a branching structureGO:0060688530.053
peptidyl serine phosphorylationGO:0018105740.052
negative regulation of intracellular signal transductionGO:19025321670.052
divalent metal ion transportGO:00708381720.052
potassium ion transmembrane transportGO:0071805430.052
negative regulation of cell growthGO:0030308440.051
positive regulation of fatty acid metabolic processGO:004592380.051
Rat
cellular response to acid chemicalGO:0071229680.051
Rat
apoptotic process involved in mammary gland involutionGO:006005740.051
regulation of intrinsic apoptotic signaling pathway in response to osmotic stressGO:190221810.050
relaxation of muscleGO:0090075180.050
brown fat cell differentiationGO:0050873360.050
regulation of long term synaptic potentiationGO:190027140.050
positive regulation of myeloid cell differentiationGO:0045639430.050
Mouse
positive regulation of homeostatic processGO:0032846640.050
regulation of map kinase activityGO:00434051200.050
organophosphate catabolic processGO:00464342320.050
synaptic transmissionGO:00072683290.050
action potentialGO:0001508780.049
membrane organizationGO:00610242450.049
response to glycosideGO:190341620.049
gliogenesisGO:00420631410.049
notochord cell developmentGO:006003510.049
positive regulation of bone remodelingGO:0046852130.049
Mouse
signal transduction by p53 class mediatorGO:0072331510.049
regulation of metal ion transportGO:00109591060.048
cellular response to extracellular stimulusGO:0031668810.048
carbohydrate homeostasisGO:00335001280.048
nucleoside phosphate catabolic processGO:19012922220.048
positive regulation of apoptotic processGO:00430652170.048
vasodilationGO:0042311280.048
negative regulation of membrane potentialGO:004583740.047
establishment of protein localization to organelleGO:00725941180.047
protein catabolic processGO:00301632210.047
response to ammonium ionGO:0060359210.047
neuron deathGO:00709971540.047
i kappab kinase nf kappab signalingGO:0007249850.047
phospholipase c activating angiotensin activated signaling pathwayGO:008609710.046
regulation of cation channel activityGO:2001257220.046
cellular response to growth factor stimulusGO:00713631970.046
regulation of establishment of protein localizationGO:00702011810.046
response to bile acidGO:190341210.046
regulation of hormone levelsGO:00108172110.046
Rat
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.046
release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:0014808120.046
negative regulation of peptidyl tyrosine phosphorylationGO:0050732170.045
development of primary female sexual characteristicsGO:0046545730.045
telencephalon cell migrationGO:0022029550.045
gluconeogenesisGO:0006094390.045
substantia nigra developmentGO:002176220.044
heart growthGO:0060419450.044
regulation of response to oxidative stressGO:1902882190.044
regulation of reproductive processGO:2000241660.044
regulation of nucleotide biosynthetic processGO:0030808340.044
angiogenesisGO:00015252010.044
mitochondrion organizationGO:00070051340.044
leukocyte migrationGO:00509001240.044
hormone secretionGO:00468791280.044
cardiac muscle tissue morphogenesisGO:0055008440.044
response to starvationGO:0042594650.044
Rat
mammary gland duct morphogenesisGO:0060603380.044
epithelial cell developmentGO:00020641590.043
response to osmotic stressGO:0006970210.043
trabecula formationGO:0060343240.043
Mouse
regulation of cellular respirationGO:0043457100.043
positive regulation of apoptotic process involved in morphogenesisGO:190233940.043
sequestering of calcium ionGO:0051208180.043
modification dependent protein catabolic processGO:00199411330.043
ribonucleotide catabolic processGO:00092612080.043
establishment or maintenance of neuroblast polarityGO:004519610.043
epidermis developmentGO:00085441870.043
positive regulation of behaviorGO:0048520400.043
regulation of peptide hormone secretionGO:0090276750.043
cellular response to hypoxiaGO:0071456170.042
Rat
regulation of protein stabilityGO:0031647520.042
cellular response to radiationGO:0071478280.042
regulation of nucleocytoplasmic transportGO:0046822730.042
camera type eye developmentGO:00430102660.042
peptidyl lysine deacetylationGO:003498310.042
gonad developmentGO:00084061410.042
mammary gland epithelium developmentGO:0061180650.042
positive regulation of glucose metabolic processGO:0010907210.041
sodium ion exportGO:007143620.041
glycerolipid biosynthetic processGO:0045017500.041
keratinocyte migrationGO:005154630.041
regulation of urea metabolic processGO:003425510.041
intrinsic apoptotic signaling pathwayGO:00971931320.040
cell cell signaling involved in lung developmentGO:006049510.040
multicellular organism growthGO:00352641610.040
cardiac muscle cell differentiationGO:0055007690.040
intestinal absorptionGO:0050892130.040
regulation of the force of heart contractionGO:0002026170.040
regulation of mesenchymal cell proliferationGO:0010464370.040
regulation of fat cell differentiationGO:0045598810.040

Ppargc1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.890
acquired metabolic diseaseDOID:006015800.854
obesityDOID:997000.459
nutrition diseaseDOID:37400.459
overnutritionDOID:65400.459
diabetes mellitusDOID:935100.172
type 2 diabetes mellitusDOID:935200.172
carbohydrate metabolism diseaseDOID:005001300.172
glucose metabolism diseaseDOID:419400.172