IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Prl6a1

prolactin family 6, subfamily a, member 1

(Aliases: PLP-B,Prlpb)

Entrez: 19111
Ensembl: ENSMUSG00000069259
UniProtKB: O35257

Process Predictions
Disease Predictions

Prl6a1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
transforming growth factor beta secretion	GO:0038044	1	0.882
regulation of transforming growth factor beta secretion	GO:2001201	1	0.820
positive regulation of transforming growth factor beta secretion	GO:2001203	1	0.742
regulation of microvillus organization	GO:0032530	3	0.667	Mouse
regulation of microvillus assembly	GO:0032534	3	0.620	Mouse
negative regulation of endothelial cell migration	GO:0010596	4	0.612	Mouse
neural precursor cell proliferation	GO:0061351	121	0.370	Mouse
negative regulation of blood vessel endothelial cell migration	GO:0043537	3	0.363	Mouse
positive regulation of nervous system development	GO:0051962	221	0.351	Mouse
positive regulation of cell development	GO:0010720	237	0.298	Mouse
regulation of stem cell proliferation	GO:0072091	78	0.283	Mouse
positive regulation of angiogenesis	GO:0045766	46	0.259	Mouse
regulation of cell projection organization	GO:0031344	206	0.257	Mouse
positive regulation of cell projection organization	GO:0031346	95	0.239	Mouse
regulation of angiogenesis	GO:0045765	81	0.238	Mouse
g protein coupled receptor signaling pathway	GO:0007186	243	0.228
regulation of cell motility	GO:2000145	236	0.214	Mouse
stem cell proliferation	GO:0072089	117	0.212	Mouse
ameboidal type cell migration	GO:0001667	128	0.175	Mouse
positive regulation of stem cell proliferation	GO:2000648	59	0.170	Mouse
regulation of vasculature development	GO:1901342	88	0.166	Mouse
neuron migration	GO:0001764	122	0.165
muscle cell differentiation	GO:0042692	261	0.162	Mouse
sensory organ morphogenesis	GO:0090596	242	0.161
diencephalon development	GO:0021536	63	0.158
muscle cell development	GO:0055001	133	0.157	Mouse
regulation of neuroblast proliferation	GO:1902692	27	0.145	Mouse
regulation of neuron differentiation	GO:0045664	281	0.144
leukocyte differentiation	GO:0002521	342	0.140
negative regulation of cell development	GO:0010721	169	0.139
chemotaxis	GO:0006935	247	0.135
immune effector process	GO:0002252	321	0.133
positive regulation of neural precursor cell proliferation	GO:2000179	42	0.121	Mouse
gland development	GO:0048732	330	0.116
epithelium migration	GO:0090132	63	0.112	Mouse
sensory perception	GO:0007600	245	0.104
positive regulation of cell migration	GO:0030335	109	0.102	Mouse
skeletal muscle fiber development	GO:0048741	58	0.097	Mouse
positive regulation of cell motility	GO:2000147	116	0.096	Mouse
response to acid chemical	GO:0001101	111	0.093
camera type eye development	GO:0043010	266	0.091
axonogenesis	GO:0007409	274	0.088
regulation of cell migration	GO:0030334	219	0.087	Mouse
telencephalon development	GO:0021537	186	0.086
muscle tissue development	GO:0060537	308	0.084	Mouse
pallium development	GO:0021543	120	0.081
regulation of muscle tissue development	GO:1901861	97	0.079	Mouse
positive regulation of neuroblast proliferation	GO:0002052	19	0.076	Mouse
forebrain development	GO:0030900	302	0.076
regulation of cellular component biogenesis	GO:0044087	181	0.075	Mouse
muscle fiber development	GO:0048747	76	0.075	Mouse
cellular response to molecule of bacterial origin	GO:0071219	83	0.073
amide transport	GO:0042886	138	0.072
cytokine production	GO:0001816	319	0.072
regulation of protein transport	GO:0051223	163	0.069
cellular response to lipid	GO:0071396	145	0.066
striated muscle tissue development	GO:0014706	293	0.065	Mouse
blood vessel morphogenesis	GO:0048514	285	0.065	Mouse
regulation of phospholipase c activity	GO:1900274	3	0.063
endothelial cell migration	GO:0043542	44	0.061	Mouse
amine metabolic process	GO:0009308	45	0.061
myotube differentiation	GO:0014902	105	0.058	Mouse
protein localization to organelle	GO:0033365	185	0.057
regulation of innate immune response	GO:0045088	91	0.057
stem cell development	GO:0048864	219	0.056
regulation of lymphocyte activation	GO:0051249	240	0.055
embryonic organ morphogenesis	GO:0048562	276	0.055
keratinocyte proliferation	GO:0043616	21	0.054
negative regulation of cellular component organization	GO:0051129	194	0.054
negative regulation of muscle cell differentiation	GO:0051148	33	0.053	Mouse
epithelial cell migration	GO:0010631	63	0.052	Mouse
axon guidance	GO:0007411	141	0.051
cardiac ventricle development	GO:0003231	83	0.050
regulation of hydrolase activity	GO:0051336	246	0.049
negative regulation of cell proliferation	GO:0008285	296	0.048
regulation of cellular amine metabolic process	GO:0033238	20	0.047
interleukin 10 secretion	GO:0072608	4	0.047
immune response activating signal transduction	GO:0002757	116	0.046
ion transmembrane transport	GO:0034220	361	0.046
jak stat cascade	GO:0007259	42	0.045
sa node cell action potential	GO:0086015	4	0.045
angiogenesis	GO:0001525	201	0.045	Mouse
cellular ketone metabolic process	GO:0042180	84	0.045
sprouting angiogenesis	GO:0002040	26	0.044	Mouse
regulation of interleukin 10 secretion	GO:2001179	4	0.044
tissue migration	GO:0090130	68	0.044	Mouse
response to molecule of bacterial origin	GO:0002237	143	0.044
digestive system development	GO:0055123	200	0.043
lymphocyte differentiation	GO:0030098	242	0.042
regulation of neural precursor cell proliferation	GO:2000177	70	0.042	Mouse
regulation of response to wounding	GO:1903034	189	0.042
learning or memory	GO:0007611	148	0.041
cellular amine metabolic process	GO:0044106	44	0.041
sodium ion transport	GO:0006814	73	0.041
regulation of neuron projection development	GO:0010975	169	0.040
cardiac chamber development	GO:0003205	108	0.040
regulation of cell activation	GO:0050865	289	0.040
cell growth	GO:0016049	130	0.040
myotube cell development	GO:0014904	60	0.040	Mouse
negative regulation of myoblast differentiation	GO:0045662	18	0.040	Mouse
positive regulation of neuron differentiation	GO:0045666	141	0.040
regulation of myotube differentiation	GO:0010830	62	0.040	Mouse
regulation of system process	GO:0044057	200	0.039
negative regulation of vasculature development	GO:1901343	26	0.038	Mouse
morphogenesis of a branching epithelium	GO:0061138	193	0.038
limb development	GO:0060173	166	0.038
muscle contraction	GO:0006936	101	0.038
regulation of transmembrane transport	GO:0034762	128	0.038
b cell activation	GO:0042113	161	0.037
positive regulation of phospholipase c activity	GO:0010863	2	0.037
morphogenesis of a polarized epithelium	GO:0001738	37	0.037
regulation of cytokine production	GO:0001817	266	0.037
morphogenesis of embryonic epithelium	GO:0016331	159	0.037
cellular amino acid metabolic process	GO:0006520	103	0.036
nitrogen compound transport	GO:0071705	271	0.036
protein kinase b signaling	GO:0043491	74	0.035
defense response to bacterium	GO:0042742	119	0.035
regulation of transferase activity	GO:0051338	263	0.035
negative regulation of blood vessel morphogenesis	GO:2000181	25	0.035	Mouse
cerebral cortex development	GO:0021987	86	0.035
positive regulation of lymphocyte activation	GO:0051251	140	0.034
negative regulation of protein metabolic process	GO:0051248	282	0.034
positive regulation of protein modification process	GO:0031401	299	0.034
inorganic ion transmembrane transport	GO:0098660	234	0.034
morphogenesis of a branching structure	GO:0001763	203	0.033
anion transport	GO:0006820	177	0.033
cellular response to lipopolysaccharide	GO:0071222	77	0.033
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.033
action potential	GO:0001508	78	0.032
positive regulation of defense response	GO:0031349	124	0.032
transmembrane transport	GO:0055085	412	0.032
rhodopsin mediated signaling pathway	GO:0016056	4	0.032
inorganic anion transport	GO:0015698	43	0.032
ear morphogenesis	GO:0042471	118	0.032
striated muscle cell development	GO:0055002	125	0.031	Mouse
positive regulation of synaptic plasticity	GO:0031915	4	0.031
regulation of action potential	GO:0098900	4	0.030
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.029
cognition	GO:0050890	149	0.029
branching morphogenesis of an epithelial tube	GO:0048754	159	0.029
regulation of organ morphogenesis	GO:2000027	144	0.029
cellular homeostasis	GO:0019725	240	0.029
regulation of kinase activity	GO:0043549	249	0.029
positive regulation of phospholipase activity	GO:0010518	3	0.029
small gtpase mediated signal transduction	GO:0007264	97	0.028
mapk cascade	GO:0000165	281	0.028
astrocyte fate commitment	GO:0060018	4	0.028
leukocyte mediated immunity	GO:0002443	174	0.028
neuroblast proliferation	GO:0007405	49	0.028	Mouse
inner ear morphogenesis	GO:0042472	101	0.028
negative regulation of nervous system development	GO:0051961	156	0.028
chromatin organization	GO:0006325	206	0.028
nucleotide metabolic process	GO:0009117	332	0.027
myeloid leukocyte mediated immunity	GO:0002444	42	0.027
cell type specific apoptotic process	GO:0097285	268	0.027
regulation of interferon gamma production	GO:0032649	57	0.027
adaptive immune response	GO:0002250	155	0.027
epithelial tube morphogenesis	GO:0060562	303	0.027
hippocampus development	GO:0021766	52	0.027
glycosyl compound metabolic process	GO:1901657	246	0.027
sensory perception of pain	GO:0019233	47	0.027
cell chemotaxis	GO:0060326	81	0.027
circadian rhythm	GO:0007623	114	0.026
cell substrate adhesion	GO:0031589	130	0.026
positive regulation of endothelial cell migration	GO:0010595	12	0.026	Mouse
positive regulation of innate immune response	GO:0045089	80	0.026
ear development	GO:0043583	200	0.026
nucleobase containing small molecule metabolic process	GO:0055086	352	0.026
positive regulation of cellular amine metabolic process	GO:0033240	5	0.026
ribose phosphate metabolic process	GO:0019693	291	0.025
cell proliferation involved in outflow tract morphogenesis	GO:0061325	4	0.025
cellular response to acid chemical	GO:0071229	68	0.025
response to drug	GO:0042493	75	0.025
response to radiation	GO:0009314	165	0.025
locomotory behavior	GO:0007626	195	0.025
tissue remodeling	GO:0048771	102	0.025
regulation of body fluid levels	GO:0050878	162	0.025
positive regulation of keratinocyte proliferation	GO:0010838	4	0.025
positive regulation of kinase activity	GO:0033674	155	0.025
negative regulation of phosphate metabolic process	GO:0045936	184	0.025
response to organonitrogen compound	GO:0010243	246	0.025
negative regulation of angiogenesis	GO:0016525	25	0.024	Mouse
apoptotic signaling pathway	GO:0097190	306	0.024
canonical wnt signaling pathway	GO:0060070	130	0.024
regulation of jak stat cascade	GO:0046425	34	0.024
regulation of organelle organization	GO:0033043	289	0.024
response to oxidative stress	GO:0006979	123	0.024
regulation of blood vessel endothelial cell migration	GO:0043535	12	0.024	Mouse
innate immune response	GO:0045087	157	0.024
retina morphogenesis in camera type eye	GO:0060042	45	0.024
ossification	GO:0001503	216	0.024
negative regulation of phosphorus metabolic process	GO:0010563	184	0.024
positive regulation of blood vessel endothelial cell migration	GO:0043536	5	0.024	Mouse
cellular response to biotic stimulus	GO:0071216	92	0.024
sodium ion transmembrane transport	GO:0035725	49	0.024
interferon gamma production	GO:0032609	67	0.024
circulatory system process	GO:0003013	197	0.024
protein localization to nucleus	GO:0034504	121	0.023
regulation of wnt signaling pathway	GO:0030111	123	0.023
peptide transport	GO:0015833	133	0.023
response to growth factor	GO:0070848	198	0.023
negative regulation of cellular protein metabolic process	GO:0032269	247	0.023
regulation of membrane potential	GO:0042391	192	0.023
endocrine system development	GO:0035270	98	0.023
regulation of mapk cascade	GO:0043408	248	0.023
regulation of protein secretion	GO:0050708	82	0.023
positive regulation of cytokine production	GO:0001819	174	0.023
myeloid cell differentiation	GO:0030099	233	0.023
placenta development	GO:0001890	140	0.023
renal system development	GO:0072001	225	0.023
cell proliferation in hindbrain	GO:0021534	10	0.023
positive regulation of hydrolase activity	GO:0051345	148	0.023
carbohydrate derivative biosynthetic process	GO:1901137	183	0.023
regulation of secretion by cell	GO:1903530	249	0.022
regulation of purine nucleotide catabolic process	GO:0033121	122	0.022
retina development in camera type eye	GO:0060041	119	0.022
midgut development	GO:0007494	4	0.022
regulation of mitotic cell cycle	GO:0007346	126	0.022
nucleocytoplasmic transport	GO:0006913	139	0.022
regulation of cellular ketone metabolic process	GO:0010565	66	0.022
positive regulation of interferon gamma production	GO:0032729	39	0.021
regulation of skeletal muscle fiber development	GO:0048742	36	0.021	Mouse
forebrain cell migration	GO:0021885	58	0.021
stem cell maintenance	GO:0019827	130	0.021
heart morphogenesis	GO:0003007	178	0.021
establishment of protein localization to organelle	GO:0072594	118	0.021
negative regulation of cell migration	GO:0030336	59	0.021	Mouse
cellular nitrogen compound catabolic process	GO:0044270	280	0.021
mitotic cell cycle	GO:0000278	195	0.021
cation transport	GO:0006812	399	0.021
regulation of binding	GO:0051098	111	0.021
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	61	0.020
divalent inorganic cation transport	GO:0072511	178	0.020
leukocyte migration	GO:0050900	124	0.020
mesenchymal cell development	GO:0014031	93	0.020
macromolecule catabolic process	GO:0009057	281	0.020
av node cell to bundle of his cell communication	GO:0086067	2	0.020
cardiac chamber morphogenesis	GO:0003206	93	0.020
atrial ventricular junction remodeling	GO:0003294	2	0.020
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.020
cell differentiation involved in embryonic placenta development	GO:0060706	26	0.020
ventricular septum development	GO:0003281	42	0.020
cardiac muscle contraction	GO:0060048	32	0.020
regulation of cellular component size	GO:0032535	121	0.019
hindbrain development	GO:0030902	128	0.019
inflammatory response	GO:0006954	244	0.019
nuclear transport	GO:0051169	139	0.019
posttranscriptional regulation of gene expression	GO:0010608	155	0.019
regulation of protein kinase b signaling	GO:0051896	56	0.019
regulation of canonical wnt signaling pathway	GO:0060828	82	0.019
regulation of establishment of protein localization	GO:0070201	181	0.019
regulation of striated muscle cell differentiation	GO:0051153	81	0.019	Mouse
chondrocyte differentiation	GO:0002062	72	0.018
branching involved in salivary gland morphogenesis	GO:0060445	26	0.018
auditory receptor cell fate specification	GO:0042667	1	0.018
blood vessel endothelial cell migration	GO:0043534	23	0.018	Mouse
stem cell differentiation	GO:0048863	268	0.018
regulation of anatomical structure size	GO:0090066	178	0.018
oligopeptide transmembrane transport	GO:0035672	4	0.018
regulation of auditory receptor cell differentiation	GO:0045607	4	0.018
positive regulation of transferase activity	GO:0051347	167	0.018
cytokine mediated signaling pathway	GO:0019221	115	0.018
positive regulation of neuron projection development	GO:0010976	79	0.018
negative regulation of growth	GO:0045926	99	0.018
sensory perception of mechanical stimulus	GO:0050954	107	0.018
purine containing compound metabolic process	GO:0072521	311	0.018
tube formation	GO:0035148	140	0.018
regulation of peptide transport	GO:0090087	91	0.017
negative regulation of neuron differentiation	GO:0045665	101	0.017
regulation of cellular catabolic process	GO:0031329	242	0.017
organophosphate biosynthetic process	GO:0090407	122	0.017
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.017
ribonucleoside metabolic process	GO:0009119	245	0.017
homeostasis of number of cells	GO:0048872	210	0.017
protein secretion	GO:0009306	111	0.017
pattern recognition receptor signaling pathway	GO:0002221	47	0.017
blood circulation	GO:0008015	195	0.017
muscle system process	GO:0003012	141	0.017
blood coagulation	GO:0007596	76	0.017
leukocyte chemotaxis	GO:0030595	69	0.017
skeletal system development	GO:0001501	356	0.017
regulation of cartilage development	GO:0061035	44	0.017
skeletal muscle organ development	GO:0060538	163	0.017	Mouse
nucleoside metabolic process	GO:0009116	246	0.016
response to amino acid	GO:0043200	37	0.016
proton transport	GO:0015992	35	0.016
wnt signaling pathway	GO:0016055	188	0.016
establishment or maintenance of neuroblast polarity	GO:0045196	1	0.016
regulation of cell adhesion	GO:0030155	154	0.016
negative regulation of immune effector process	GO:0002698	55	0.016
septum primum development	GO:0003284	4	0.016
regionalization	GO:0003002	337	0.016
embryonic placenta development	GO:0001892	98	0.016
limbic system development	GO:0021761	72	0.016
regulation of apoptotic signaling pathway	GO:2001233	197	0.016
response to lipopolysaccharide	GO:0032496	128	0.016
negative regulation of molecular function	GO:0044092	258	0.016
activation of innate immune response	GO:0002218	56	0.016
regulation of epithelial cell migration	GO:0010632	35	0.016	Mouse
response to nutrient levels	GO:0031667	109	0.016
regulation of myoblast differentiation	GO:0045661	29	0.016	Mouse
innate immune response activating signal transduction	GO:0002758	50	0.016
developmental growth involved in morphogenesis	GO:0060560	138	0.016
mitral valve development	GO:0003174	4	0.016
regulation of extent of cell growth	GO:0061387	52	0.016
t cell activation	GO:0042110	289	0.016
photoreceptor cell development	GO:0042461	40	0.015
organonitrogen compound biosynthetic process	GO:1901566	192	0.015
regulation of hormone secretion	GO:0046883	88	0.015
somitogenesis	GO:0001756	69	0.015
fat cell differentiation	GO:0045444	160	0.015
single organism nuclear import	GO:1902593	95	0.015
regulation of actin filament based process	GO:0032970	99	0.015
coagulation	GO:0050817	78	0.015
carbohydrate derivative catabolic process	GO:1901136	231	0.015
negative regulation of cell motility	GO:2000146	61	0.015	Mouse
regulation of fat cell differentiation	GO:0045598	81	0.015
myeloid leukocyte differentiation	GO:0002573	119	0.015
regulation of t cell activation	GO:0050863	170	0.015
neural tube development	GO:0021915	160	0.015
ventricular cardiac muscle cell action potential	GO:0086005	4	0.015
cell adhesion	GO:0007155	329	0.015
regulation of neural retina development	GO:0061074	3	0.015
heart contraction	GO:0060047	93	0.015
regulation of protein localization	GO:0032880	231	0.015
gliogenesis	GO:0042063	141	0.015
nucleoside catabolic process	GO:0009164	206	0.015
mesoderm development	GO:0007498	100	0.015
sensory perception of light stimulus	GO:0050953	54	0.015
transmission of nerve impulse	GO:0019226	76	0.015
lymphocyte mediated immunity	GO:0002449	139	0.015
regulation of chromatin organization	GO:1902275	57	0.015
neuromuscular process	GO:0050905	99	0.014
regulation of muscle system process	GO:0090257	80	0.014
activation of phospholipase c activity	GO:0007202	2	0.014
chloride transport	GO:0006821	32	0.014
regulation of cell growth	GO:0001558	91	0.014
single organismal cell cell adhesion	GO:0016337	131	0.014
canonical wnt signaling pathway involved in regulation of cell proliferation	GO:0044340	3	0.014
mesenchyme development	GO:0060485	152	0.014
carboxylic acid transport	GO:0046942	100	0.014
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger	GO:0007187	55	0.014
telencephalon cell migration	GO:0022029	55	0.014
positive regulation of camp mediated signaling	GO:0043950	3	0.014
humoral immune response	GO:0006959	57	0.014
calcium ion transport	GO:0006816	159	0.014
tube closure	GO:0060606	91	0.014
cation transmembrane transport	GO:0098655	266	0.014
dephosphorylation	GO:0016311	129	0.014
inorganic anion transmembrane transport	GO:0098661	29	0.014
negative regulation of myeloid cell differentiation	GO:0045638	38	0.014
neuron apoptotic process	GO:0051402	142	0.014
kidney development	GO:0001822	213	0.014
adult behavior	GO:0030534	135	0.014
cell communication by chemical coupling	GO:0010643	2	0.014
positive regulation of protein transport	GO:0051222	93	0.014
bmp signaling pathway	GO:0030509	93	0.014
detection of external stimulus	GO:0009581	61	0.014
digestive tract development	GO:0048565	190	0.014
wound healing	GO:0042060	157	0.014
activation of immune response	GO:0002253	138	0.014
regulation of cytoskeleton organization	GO:0051493	122	0.013
organic cyclic compound catabolic process	GO:1901361	295	0.013
detection of abiotic stimulus	GO:0009582	60	0.013
regulation of purine nucleotide metabolic process	GO:1900542	169	0.013
adult locomotory behavior	GO:0008344	91	0.013
protein catabolic process	GO:0030163	221	0.013
asymmetric neuroblast division	GO:0055059	1	0.013
extracellular structure organization	GO:0043062	148	0.013
autonomic nervous system development	GO:0048483	43	0.013
negative regulation of cell cycle	GO:0045786	123	0.013
embryonic appendage morphogenesis	GO:0035113	126	0.013
brain segmentation	GO:0035284	3	0.013
nuclear import	GO:0051170	95	0.013
protein processing	GO:0016485	163	0.013
purine ribonucleoside metabolic process	GO:0046128	241	0.013
neuron projection guidance	GO:0097485	141	0.013
regulation of leukocyte proliferation	GO:0070663	121	0.013
ribonucleotide biosynthetic process	GO:0009260	59	0.013
lipid localization	GO:0010876	126	0.013
hemostasis	GO:0007599	78	0.013
regulation of tube size	GO:0035150	57	0.013
molting cycle	GO:0042303	90	0.013
myoblast differentiation	GO:0045445	52	0.013	Mouse
face morphogenesis	GO:0060325	29	0.013
regulation of myeloid cell differentiation	GO:0045637	96	0.013
chromatin modification	GO:0016568	187	0.013
cellular response to oxidative stress	GO:0034599	76	0.013
regulation of proteolysis	GO:0030162	164	0.013
rhythmic process	GO:0048511	174	0.013
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process	GO:2000763	1	0.013
metanephric loop of henle development	GO:0072236	4	0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.013
organelle localization	GO:0051640	179	0.013
foramen ovale closure	GO:0035922	1	0.013
satellite cell activation involved in skeletal muscle regeneration	GO:0014901	3	0.013
cellular response to organic cyclic compound	GO:0071407	87	0.013
negative regulation of phosphorylation	GO:0042326	166	0.013
regulation of exocytosis	GO:0017157	61	0.013
negative regulation of neuron projection development	GO:0010977	50	0.013
sensory system development	GO:0048880	3	0.013
regulation of extrinsic apoptotic signaling pathway	GO:2001236	77	0.013
embryonic heart tube formation	GO:0003144	1	0.013
regulation of renin secretion into blood stream	GO:1900133	4	0.013
odontogenesis	GO:0042476	78	0.013
asymmetric stem cell division	GO:0098722	3	0.013
hormone secretion	GO:0046879	128	0.012
negative regulation of cell projection organization	GO:0031345	56	0.012
cellular response to organonitrogen compound	GO:0071417	145	0.012
binding of sperm to zona pellucida	GO:0007339	34	0.012
organonitrogen compound catabolic process	GO:1901565	264	0.012
glial cell differentiation	GO:0010001	131	0.012
fat cell proliferation	GO:0070341	4	0.012
negative regulation of hydrolase activity	GO:0051346	71	0.012
endodermal cell fate specification	GO:0001714	4	0.012
sclerotome development	GO:0061056	4	0.012
auditory receptor cell fate determination	GO:0042668	3	0.012
regulation of secretion	GO:0051046	274	0.012
positive regulation of secretion	GO:0051047	130	0.012
cellular response to external stimulus	GO:0071496	88	0.012
protein oligomerization	GO:0051259	67	0.012
blastocyst formation	GO:0001825	33	0.012
cellular response to growth factor stimulus	GO:0071363	197	0.012
purine ribonucleotide metabolic process	GO:0009150	290	0.012
nucleoside phosphate metabolic process	GO:0006753	338	0.012
positive regulation of jak stat cascade	GO:0046427	22	0.012
peptidyl tyrosine phosphorylation	GO:0018108	143	0.012
detection of stimulus	GO:0051606	84	0.012
negative regulation of cytokine production	GO:0001818	84	0.012
regulation of leukocyte mediated immunity	GO:0002703	104	0.012
aromatic compound catabolic process	GO:0019439	286	0.012
organic anion transport	GO:0015711	137	0.012
leukocyte homeostasis	GO:0001776	79	0.012
cellular chemical homeostasis	GO:0055082	215	0.012
peptide secretion	GO:0002790	114	0.012
regulation of protein kinase activity	GO:0045859	232	0.012
regulation of endothelial cell migration	GO:0010594	22	0.012	Mouse
regulation of ion transmembrane transport	GO:0034765	119	0.012
protein modification by small protein conjugation or removal	GO:0070647	207	0.012
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.012
intracellular protein transport	GO:0006886	204	0.012
regulation of fat cell proliferation	GO:0070344	4	0.012
hemangioblast cell differentiation	GO:0060217	1	0.012
striated muscle contraction	GO:0006941	45	0.012
regulation of ion transport	GO:0043269	215	0.012
osteoclast differentiation	GO:0030316	62	0.012
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	54	0.012
regulation of histone modification	GO:0031056	56	0.012
heart process	GO:0003015	94	0.012
platelet derived growth factor receptor signaling pathway	GO:0048008	32	0.012
second messenger mediated signaling	GO:0019932	73	0.011
oxidation reduction process	GO:0055114	342	0.011
trunk segmentation	GO:0035290	4	0.011
positive regulation of cell morphogenesis involved in differentiation	GO:0010770	72	0.011
negative regulation of oxidative phosphorylation uncoupler activity	GO:2000276	2	0.011
ribonucleotide metabolic process	GO:0009259	291	0.011
regulation of cellular response to stress	GO:0080135	159	0.011
covalent chromatin modification	GO:0016569	163	0.011
positive regulation of epithelial cell migration	GO:0010634	19	0.011	Mouse
response to oxygen levels	GO:0070482	62	0.011
neuron projection extension	GO:1990138	64	0.011
developmental cell growth	GO:0048588	84	0.011
cellular response to hormone stimulus	GO:0032870	150	0.011
actin mediated cell contraction	GO:0070252	15	0.011
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.011
small molecule biosynthetic process	GO:0044283	132	0.011
visual perception	GO:0007601	52	0.011
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.011
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.011
response to transforming growth factor beta	GO:0071559	88	0.011
negative regulation of cell fate specification	GO:0009996	4	0.011
positive regulation of protein phosphorylation	GO:0001934	242	0.011
pigmentation	GO:0043473	71	0.011
inorganic cation transmembrane transport	GO:0098662	207	0.011
multi multicellular organism process	GO:0044706	109	0.011
positive regulation of cell death	GO:0010942	224	0.011
somatic stem cell maintenance	GO:0035019	47	0.011
germ cell development	GO:0007281	185	0.011
phospholipid metabolic process	GO:0006644	87	0.011
skin development	GO:0043588	220	0.011
organic hydroxy compound metabolic process	GO:1901615	203	0.011
blastocyst development	GO:0001824	80	0.011
regulation of cell size	GO:0008361	72	0.011
t cell differentiation	GO:0030217	174	0.011
regulation of protein processing	GO:0070613	96	0.011
appendage development	GO:0048736	166	0.011
cellular response to antibiotic	GO:0071236	4	0.011
cardiac septum development	GO:0003279	59	0.011
response to organic cyclic compound	GO:0014070	198	0.011
pancreatic pp cell fate commitment	GO:0003329	2	0.011
regulation of multi organism process	GO:0043900	111	0.011

Prl6a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.044
nervous system disease	DOID:863	0.044
musculoskeletal system disease	DOID:17	0.017
connective tissue disease	DOID:65	0.017
sensory system disease	DOID:0050155	0.015
eye and adnexa disease	DOID:1492	0.015
bone disease	DOID:0080001	0.012

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