IMP: Integrative Multi-species Prediction

Mus musculus

148 known processes

Prop1

paired like homeodomain factor 1

(Aliases: df,Prop-1)

Entrez: 19127
Ensembl: ENSMUSG00000044542
UniProtKB: P97458

Process Predictions
Disease Predictions

Prop1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
negative regulation of cell proliferation	GO:0008285	296	0.788
gland development	GO:0048732	330	0.761
pituitary gland development	GO:0021983	38	0.722
renal tubule development	GO:0061326	87	0.715
striated muscle tissue development	GO:0014706	293	0.693
regulation of peptide hormone secretion	GO:0090276	75	0.678
forebrain development	GO:0030900	302	0.657
nitrogen compound transport	GO:0071705	271	0.645
regulation of leukocyte proliferation	GO:0070663	121	0.628
ion transmembrane transport	GO:0034220	361	0.560
regulation of inflammatory response	GO:0050727	147	0.546
positive regulation of secretion	GO:0051047	130	0.537
polarity specification of proximal distal axis	GO:0010085	2	0.523
regulation of secretion by cell	GO:1903530	249	0.517
camera type eye development	GO:0043010	266	0.504	Mouse
anion transport	GO:0006820	177	0.489
cardiac ventricle development	GO:0003231	83	0.465
response to organonitrogen compound	GO:0010243	246	0.462
sensory perception	GO:0007600	245	0.446
amide transport	GO:0042886	138	0.439
oviduct development	GO:0060066	3	0.437
inflammatory response	GO:0006954	244	0.428
ribonucleotide metabolic process	GO:0009259	291	0.425
metanephric nephron morphogenesis	GO:0072273	19	0.409
regulation of lipid metabolic process	GO:0019216	118	0.402	Mouse
insulin secretion	GO:0030073	89	0.401
heart morphogenesis	GO:0003007	178	0.401
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger	GO:0007187	55	0.396
cardiac chamber morphogenesis	GO:0003206	93	0.389
cardiac chamber development	GO:0003205	108	0.382
regulation of lymphocyte proliferation	GO:0050670	117	0.368
peptide secretion	GO:0002790	114	0.366
cervix development	GO:0060067	2	0.356
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.355
embryonic organ morphogenesis	GO:0048562	276	0.350
peptide hormone secretion	GO:0030072	109	0.347
cellular amine metabolic process	GO:0044106	44	0.347
wnt signaling pathway	GO:0016055	188	0.338
ureteric bud development	GO:0001657	94	0.336
stem cell development	GO:0048864	219	0.331
cardiac cell fate determination	GO:0060913	2	0.323
hormone secretion	GO:0046879	128	0.316
diencephalon development	GO:0021536	63	0.315
ribose phosphate biosynthetic process	GO:0046390	59	0.310
neuron fate specification	GO:0048665	30	0.304	Worm
regulation of response to wounding	GO:1903034	189	0.301
cell fate commitment	GO:0045165	210	0.292	Worm
positive regulation of cellular amine metabolic process	GO:0033240	5	0.288
kidney epithelium development	GO:0072073	121	0.283
endocrine system development	GO:0035270	98	0.281
stem cell differentiation	GO:0048863	268	0.276
amine metabolic process	GO:0009308	45	0.272
paramesonephric duct development	GO:0061205	3	0.270
neuron apoptotic process	GO:0051402	142	0.264
nephron epithelium development	GO:0072009	92	0.260
cerebral cortex development	GO:0021987	86	0.258
mesonephric epithelium development	GO:0072163	94	0.257
protein kinase b signaling	GO:0043491	74	0.254
organonitrogen compound biosynthetic process	GO:1901566	192	0.254
cardiac muscle tissue morphogenesis	GO:0055008	44	0.253
positive regulation of cytokine production	GO:0001819	174	0.245
regulation of cellular amino acid metabolic process	GO:0006521	5	0.244
digestive system development	GO:0055123	200	0.239
male sex differentiation	GO:0046661	109	0.239
renal tubule morphogenesis	GO:0061333	72	0.238
muscle cell differentiation	GO:0042692	261	0.238
muscle tissue development	GO:0060537	308	0.236
purine containing compound biosynthetic process	GO:0072522	70	0.236
positive regulation of peptide secretion	GO:0002793	33	0.234
cell maturation	GO:0048469	127	0.234
peptide transport	GO:0015833	133	0.232
regulation of dopamine secretion	GO:0014059	9	0.231
telencephalon development	GO:0021537	186	0.227
nucleoside phosphate biosynthetic process	GO:1901293	79	0.227
positive regulation of secretion by cell	GO:1903532	114	0.227
synaptic transmission	GO:0007268	329	0.224
regulation of vesicle mediated transport	GO:0060627	139	0.223
branching morphogenesis of an epithelial tube	GO:0048754	159	0.223
sensory organ morphogenesis	GO:0090596	242	0.222
catecholamine uptake	GO:0090493	4	0.220
regulation of cell cycle	GO:0051726	281	0.218
regulation of anterior head development	GO:2000742	2	0.215
developmental maturation	GO:0021700	193	0.215
purine ribonucleotide metabolic process	GO:0009150	290	0.207
germ cell development	GO:0007281	185	0.206	Mouse
positive regulation of leukocyte proliferation	GO:0070665	73	0.204
leukocyte proliferation	GO:0070661	172	0.200
lung induction	GO:0060492	3	0.199
forebrain generation of neurons	GO:0021872	63	0.199
neural tube development	GO:0021915	160	0.198
kidney development	GO:0001822	213	0.195
ventricular cardiac muscle tissue morphogenesis	GO:0055010	32	0.194
nephron morphogenesis	GO:0072028	69	0.193
organ growth	GO:0035265	117	0.193
regulation of cell motility	GO:2000145	236	0.192
hypophysis morphogenesis	GO:0048850	3	0.191
regulation of cellular ketone metabolic process	GO:0010565	66	0.191
digestive tract development	GO:0048565	190	0.190
nucleoside phosphate metabolic process	GO:0006753	338	0.188
sensory perception of pain	GO:0019233	47	0.183
purine ribonucleotide biosynthetic process	GO:0009152	59	0.182
regulation of fat cell differentiation	GO:0045598	81	0.182
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.179
cellular amino acid metabolic process	GO:0006520	103	0.178
limbic system development	GO:0021761	72	0.177
regulation of wnt signaling pathway	GO:0030111	123	0.175
cardiac septum morphogenesis	GO:0060411	46	0.174
muscle tissue morphogenesis	GO:0060415	53	0.172
central nervous system neuron differentiation	GO:0021953	162	0.172
somatostatin signaling pathway	GO:0038170	2	0.171
regulation of homeostatic process	GO:0032844	182	0.163
negative regulation of canonical wnt signaling pathway	GO:0090090	51	0.160
horizontal cell localization	GO:0035852	1	0.158
cell type specific apoptotic process	GO:0097285	268	0.156
negative regulation of wnt signaling pathway	GO:0030178	73	0.155
regulation of cytokine production	GO:0001817	266	0.155
cyclic purine nucleotide metabolic process	GO:0052652	43	0.155
renal inner medulla development	GO:0072053	3	0.153
ureteric bud morphogenesis	GO:0060675	62	0.152
cellular response to hormone stimulus	GO:0032870	150	0.151
positive regulation of growth	GO:0045927	104	0.151
nephric duct elongation	GO:0035849	1	0.150
multicellular organismal homeostasis	GO:0048871	164	0.150
cytokine production	GO:0001816	319	0.149
positive regulation of renal sodium excretion	GO:0035815	2	0.148
neural precursor cell proliferation	GO:0061351	121	0.148
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	61	0.147
purine nucleotide biosynthetic process	GO:0006164	65	0.144
appendage development	GO:0048736	166	0.143	Mouse
g protein coupled receptor signaling pathway	GO:0007186	243	0.142
regulation of secretion	GO:0051046	274	0.142
positive regulation of cell migration	GO:0030335	109	0.139
epithelial tube morphogenesis	GO:0060562	303	0.138
digestive tract morphogenesis	GO:0048546	147	0.138
regulation of cellular amine metabolic process	GO:0033238	20	0.138
anterior head development	GO:0097065	2	0.136
nephron tubule morphogenesis	GO:0072078	68	0.135
regulation of asymmetric cell division	GO:0009786	4	0.135
positive regulation of macrophage colony stimulating factor production	GO:1901258	1	0.134
regionalization	GO:0003002	337	0.134
germ line stem cell division	GO:0042078	2	0.134
organic acid transport	GO:0015849	101	0.133
central nervous system vasculogenesis	GO:0022009	3	0.131
renal vesicle development	GO:0072087	17	0.128
regulation of camp metabolic process	GO:0030814	30	0.128
regulation of renal sodium excretion	GO:0035813	3	0.127
purine containing compound metabolic process	GO:0072521	311	0.126
organophosphate biosynthetic process	GO:0090407	122	0.126
heart contraction	GO:0060047	93	0.126
ribose phosphate metabolic process	GO:0019693	291	0.125
positive regulation of cell motility	GO:2000147	116	0.125
nuclear transport	GO:0051169	139	0.123
response to extracellular stimulus	GO:0009991	127	0.123
morphogenesis of a branching structure	GO:0001763	203	0.123
cardiocyte differentiation	GO:0035051	87	0.123
cyclic nucleotide biosynthetic process	GO:0009190	44	0.120
regulation of protein localization	GO:0032880	231	0.120
regulation of neuron differentiation	GO:0045664	281	0.120
positive regulation of peptide hormone secretion	GO:0090277	31	0.117
regulation of defense response	GO:0031347	233	0.117
neurohypophysis development	GO:0021985	2	0.117
mesoderm development	GO:0007498	100	0.114
regulation of canonical wnt signaling pathway	GO:0060828	82	0.113
regulation of vascular endothelial growth factor production	GO:0010574	13	0.113
formation of primary germ layer	GO:0001704	77	0.111
spermatogenesis	GO:0007283	284	0.111
blood vessel morphogenesis	GO:0048514	285	0.110
negative regulation of defense response	GO:0031348	77	0.109
regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045898	2	0.108
axonogenesis	GO:0007409	274	0.108
fat cell differentiation	GO:0045444	160	0.108
development of primary male sexual characteristics	GO:0046546	88	0.108
positive regulation of cyclic nucleotide biosynthetic process	GO:0030804	24	0.108
renal system development	GO:0072001	225	0.108
positive regulation of inositol phosphate biosynthetic process	GO:0060732	2	0.108
peptidyl tyrosine modification	GO:0018212	145	0.107
regulation of purine nucleotide biosynthetic process	GO:1900371	34	0.106
mesonephros development	GO:0001823	97	0.104
negative regulation of neuron death	GO:1901215	98	0.104
blastocyst development	GO:0001824	80	0.104
positive regulation of apoptotic process	GO:0043065	217	0.104
cell proliferation in forebrain	GO:0021846	30	0.103
regulation of body fluid levels	GO:0050878	162	0.103
regulation of peptide secretion	GO:0002791	77	0.103
nephron development	GO:0072006	109	0.102
urogenital system development	GO:0001655	261	0.101
skeletal muscle organ development	GO:0060538	163	0.101
regulation of nephron tubule epithelial cell differentiation	GO:0072182	9	0.101
metanephric dct cell differentiation	GO:0072240	3	0.101
blood circulation	GO:0008015	195	0.100
stem cell maintenance	GO:0019827	130	0.100
ribonucleotide biosynthetic process	GO:0009260	59	0.098
catecholamine metabolic process	GO:0006584	30	0.097
cellular ketone metabolic process	GO:0042180	84	0.097
metal ion homeostasis	GO:0055065	189	0.097
g protein coupled receptor internalization	GO:0002031	3	0.097
nucleotide biosynthetic process	GO:0009165	78	0.096
regulation of ossification	GO:0030278	112	0.095
limb development	GO:0060173	166	0.095	Mouse
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	54	0.095
kidney morphogenesis	GO:0060993	83	0.095
regulation of stem cell differentiation	GO:2000736	50	0.095
regulation of organ growth	GO:0046620	61	0.095
ensheathment of neurons	GO:0007272	76	0.094
metanephric loop of henle development	GO:0072236	4	0.094
regulation of hormone secretion	GO:0046883	88	0.093
regulation of nucleotide biosynthetic process	GO:0030808	34	0.093
morphogenesis of a branching epithelium	GO:0061138	193	0.092
carboxylic acid transport	GO:0046942	100	0.092
nucleotide metabolic process	GO:0009117	332	0.092
lymphocyte proliferation	GO:0046651	164	0.091
positive regulation of lymphocyte proliferation	GO:0050671	70	0.091
regulation of cell migration	GO:0030334	219	0.090
regulation of morphogenesis of a branching structure	GO:0060688	53	0.090
positive regulation of protein transport	GO:0051222	93	0.089
regulation of neural precursor cell proliferation	GO:2000177	70	0.088
cellular response to growth factor stimulus	GO:0071363	197	0.088
somatostatin receptor signaling pathway	GO:0038169	2	0.088
male gamete generation	GO:0048232	285	0.088
purine nucleotide metabolic process	GO:0006163	302	0.088
embryonic epithelial tube formation	GO:0001838	130	0.087
cardiac muscle tissue development	GO:0048738	130	0.087
axon guidance	GO:0007411	141	0.087
lymphocyte differentiation	GO:0030098	242	0.087
angiogenesis	GO:0001525	201	0.087
motor neuron migration	GO:0097475	4	0.087
negative regulation of epithelial cell proliferation	GO:0050680	64	0.086
dorsal ventral axon guidance	GO:0033563	3	0.086
regulation of nucleotide metabolic process	GO:0006140	169	0.085
skeletal system development	GO:0001501	356	0.085
regulation of neuron apoptotic process	GO:0043523	122	0.085
regulation of interleukin 1 alpha production	GO:0032650	4	0.085
negative regulation of phosphorus metabolic process	GO:0010563	184	0.085
sensory system development	GO:0048880	3	0.084
learning or memory	GO:0007611	148	0.084
cellular homeostasis	GO:0019725	240	0.084
lateral motor column neuron migration	GO:0097477	3	0.083
regulation of mapk cascade	GO:0043408	248	0.082
regulation of kidney development	GO:0090183	40	0.082
cardiac ventricle morphogenesis	GO:0003208	50	0.081
regulation of purine nucleotide metabolic process	GO:1900542	169	0.081
gastrulation	GO:0007369	116	0.081
apoptotic signaling pathway	GO:0097190	306	0.080
regulation of lyase activity	GO:0051339	13	0.080
cell differentiation involved in kidney development	GO:0061005	33	0.080
forebrain neuron differentiation	GO:0021879	52	0.080
cellular response to lipid	GO:0071396	145	0.078
endoderm development	GO:0007492	45	0.078
positive regulation of programmed cell death	GO:0043068	218	0.078
regulation of cyclic nucleotide metabolic process	GO:0030799	40	0.077
maintenance of apical basal cell polarity	GO:0035090	3	0.077
positive regulation of catecholamine uptake involved in synaptic transmission	GO:0051944	2	0.077
transmission of nerve impulse	GO:0019226	76	0.077
skin development	GO:0043588	220	0.076
negative regulation of cell development	GO:0010721	169	0.076
endoderm formation	GO:0001706	20	0.076
gliogenesis	GO:0042063	141	0.075
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly	GO:0045899	2	0.074
cellular response to steroid hormone stimulus	GO:0071383	33	0.074
regulation of t cell activation	GO:0050863	170	0.073
negative regulation of glial cell proliferation	GO:0060253	4	0.073
t cell activation	GO:0042110	289	0.073
regulation of granulocyte macrophage colony stimulating factor production	GO:0032645	3	0.072
ameboidal type cell migration	GO:0001667	128	0.072
cell growth	GO:0016049	130	0.072
regulation of protein secretion	GO:0050708	82	0.072
regulation of membrane potential	GO:0042391	192	0.071
granulocyte macrophage colony stimulating factor production	GO:0032604	3	0.071
adult behavior	GO:0030534	135	0.071
detection of external stimulus	GO:0009581	61	0.071
muscle cell development	GO:0055001	133	0.071
ossification	GO:0001503	216	0.071
response to acid chemical	GO:0001101	111	0.070
response to radiation	GO:0009314	165	0.070
positive regulation of granulocyte macrophage colony stimulating factor production	GO:0032725	3	0.070
b cell proliferation	GO:0042100	53	0.069
response to organic cyclic compound	GO:0014070	198	0.069
positive regulation of epithelial cell differentiation involved in kidney development	GO:2000698	2	0.069
neuron projection guidance	GO:0097485	141	0.069
ectodermal cell differentiation	GO:0010668	3	0.068
metanephric tubule development	GO:0072170	18	0.068
negative regulation of response to wounding	GO:1903035	77	0.068
negative regulation of neuron apoptotic process	GO:0043524	92	0.068
positive regulation of protein modification process	GO:0031401	299	0.068
negative regulation of cell activation	GO:0050866	111	0.067
spemann organizer formation	GO:0060061	2	0.067
somatotropin secreting cell development	GO:0060133	2	0.067
mesonephric tubule morphogenesis	GO:0072171	63	0.066
epithelial cell development	GO:0002064	159	0.066
purine nucleoside metabolic process	GO:0042278	241	0.066
regulation of actin filament based process	GO:0032970	99	0.066
anatomical structure homeostasis	GO:0060249	145	0.066
positive regulation of nucleotide biosynthetic process	GO:0030810	26	0.066
carbohydrate derivative biosynthetic process	GO:1901137	183	0.066
lung field specification	GO:0060424	3	0.065
neuron death	GO:0070997	154	0.065
skeletal muscle fiber development	GO:0048741	58	0.065
peptidyl tyrosine phosphorylation	GO:0018108	143	0.065
cellular response to organic cyclic compound	GO:0071407	87	0.065
negative regulation of histone h3 k9 methylation	GO:0051573	4	0.065
ectoderm formation	GO:0001705	3	0.064
posttranscriptional regulation of gene expression	GO:0010608	155	0.064
type b pancreatic cell proliferation	GO:0044342	10	0.064
carbohydrate homeostasis	GO:0033500	128	0.064
regulation of macrophage colony stimulating factor production	GO:1901256	1	0.064
small molecule biosynthetic process	GO:0044283	132	0.064
dopamine uptake involved in synaptic transmission	GO:0051583	4	0.064
ventral spinal cord interneuron fate commitment	GO:0060579	14	0.063
epithelial cell proliferation	GO:0050673	174	0.063
ventral spinal cord interneuron specification	GO:0021521	11	0.063
positive regulation vascular endothelial growth factor production	GO:0010575	10	0.063
cation homeostasis	GO:0055080	212	0.062
skeletal system morphogenesis	GO:0048705	203	0.062
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.062
catecholamine secretion	GO:0050432	15	0.062
stem cell proliferation	GO:0072089	117	0.061
cerebellar purkinje cell differentiation	GO:0021702	13	0.061
odontogenesis of dentin containing tooth	GO:0042475	66	0.061
mesenchyme development	GO:0060485	152	0.061
detection of stimulus	GO:0051606	84	0.061
positive regulation of cell death	GO:0010942	224	0.061
negative regulation of lyase activity	GO:0051350	1	0.061
cellular response to nutrient levels	GO:0031669	64	0.061
nephron epithelium morphogenesis	GO:0072088	68	0.060
negative regulation of secretion	GO:0051048	61	0.060
b cell activation	GO:0042113	161	0.060
regulation of hydrolase activity	GO:0051336	246	0.059
negative regulation of inflammatory response	GO:0050728	61	0.059
bone remodeling	GO:0046849	53	0.059
renal vesicle morphogenesis	GO:0072077	15	0.059
protein localization to organelle	GO:0033365	185	0.059
action potential	GO:0001508	78	0.059
mesenchyme morphogenesis	GO:0072132	32	0.059
somatotropin secreting cell differentiation	GO:0060126	4	0.059
adaptive immune response	GO:0002250	155	0.059
regulation of stem cell proliferation	GO:0072091	78	0.058
protein localization to nucleus	GO:0034504	121	0.058
placenta development	GO:0001890	140	0.058	Mouse
exocytosis	GO:0006887	121	0.058
organic anion transport	GO:0015711	137	0.058
positive regulation of insulin secretion	GO:0032024	26	0.058
positive regulation of dopamine uptake involved in synaptic transmission	GO:0051586	2	0.057
cation transport	GO:0006812	399	0.057
cellular chemical homeostasis	GO:0055082	215	0.057
positive regulation of nucleotide metabolic process	GO:0045981	114	0.056
cellular ion homeostasis	GO:0006873	165	0.056
mechanoreceptor differentiation	GO:0042490	67	0.056
regulation of saliva secretion	GO:0046877	2	0.056
positive regulation of lymphocyte activation	GO:0051251	140	0.056
medial motor column neuron differentiation	GO:0021526	2	0.055
b cell differentiation	GO:0030183	78	0.055
developmental growth involved in morphogenesis	GO:0060560	138	0.055
regulation of ion transport	GO:0043269	215	0.055
regulation of cyclic nucleotide biosynthetic process	GO:0030802	31	0.055
cell fate commitment involved in pattern specification	GO:0060581	14	0.055
granulocyte colony stimulating factor production	GO:0071611	1	0.055
peripheral nervous system neuron axonogenesis	GO:0048936	3	0.054
positive regulation of branching involved in ureteric bud morphogenesis	GO:0090190	18	0.054
metanephros morphogenesis	GO:0003338	24	0.054
negative regulation of phosphate metabolic process	GO:0045936	184	0.054
developmental cell growth	GO:0048588	84	0.054
mesodermal cell fate commitment	GO:0001710	17	0.054
positive regulation of camp mediated signaling	GO:0043950	3	0.054
negative regulation of intracellular signal transduction	GO:1902532	167	0.054
organic hydroxy compound metabolic process	GO:1901615	203	0.053
negative regulation of adenylate cyclase activity	GO:0007194	1	0.053
camp biosynthetic process	GO:0006171	31	0.053
retina development in camera type eye	GO:0060041	119	0.052
cyclic nucleotide metabolic process	GO:0009187	59	0.052
membrane depolarization	GO:0051899	64	0.052
left lung morphogenesis	GO:0060460	3	0.052
ventricular cardiac muscle tissue development	GO:0003229	38	0.051
regulation of isoprenoid metabolic process	GO:0019747	1	0.051	Mouse
cell fate determination	GO:0001709	32	0.051
male gonad development	GO:0008584	88	0.051
respiratory system development	GO:0060541	190	0.051
regulation of cell activation	GO:0050865	289	0.051
embryonic skeletal system morphogenesis	GO:0048704	91	0.051
carbohydrate biosynthetic process	GO:0016051	74	0.051
immune effector process	GO:0002252	321	0.050
lipid transport	GO:0006869	98	0.050
positive regulation of transcription via serum response element binding	GO:0010735	1	0.050
negative regulation of neuron differentiation	GO:0045665	101	0.050
neurotransmitter secretion	GO:0007269	62	0.050
regulation of establishment of protein localization	GO:0070201	181	0.050
striated muscle cell development	GO:0055002	125	0.050
regulation of apoptotic signaling pathway	GO:2001233	197	0.050
dopamine uptake	GO:0090494	4	0.049
trabecular meshwork development	GO:0002930	2	0.049
response to steroid hormone	GO:0048545	56	0.049
bmp signaling pathway	GO:0030509	93	0.049
musculoskeletal movement spinal reflex action	GO:0050883	3	0.049
cellular response to external stimulus	GO:0071496	88	0.049
negative regulation of secretion by cell	GO:1903531	54	0.049
spinal cord patterning	GO:0021511	25	0.048
cellular response to carbohydrate stimulus	GO:0071322	50	0.048
epithalamus development	GO:0021538	2	0.048
cellular response to starvation	GO:0009267	57	0.048
positive regulation of carbohydrate metabolic process	GO:0045913	30	0.048
multicellular organismal response to stress	GO:0033555	62	0.048
renal vesicle induction	GO:0072034	3	0.047
epidermis development	GO:0008544	187	0.047
protein secretion	GO:0009306	111	0.047
gabaergic neuron differentiation	GO:0097154	11	0.047
cardiac muscle cell differentiation	GO:0055007	69	0.047
sensory perception of mechanical stimulus	GO:0050954	107	0.047
regulation of feeding behavior	GO:0060259	3	0.047
pallium development	GO:0021543	120	0.047
regulation of epithelial cell differentiation involved in kidney development	GO:2000696	10	0.047
negative regulation of nervous system development	GO:0051961	156	0.046
innate immune response	GO:0045087	157	0.046
cellular lipid metabolic process	GO:0044255	323	0.046	Mouse
negative regulation of protein metabolic process	GO:0051248	282	0.046
leukocyte differentiation	GO:0002521	342	0.046
regulation of dna binding	GO:0051101	39	0.045
cerebellar cortex formation	GO:0021697	22	0.045
transmembrane transport	GO:0055085	412	0.045
cytokine secretion	GO:0050663	72	0.045
maintenance of location	GO:0051235	89	0.045
nephron tubule development	GO:0072080	84	0.045
establishment of endothelial blood brain barrier	GO:0014045	3	0.044
metanephric renal vesicle morphogenesis	GO:0072283	12	0.044
osteoclast differentiation	GO:0030316	62	0.044
regulation of glucose metabolic process	GO:0010906	60	0.044
loop of henle development	GO:0072070	10	0.044
retina morphogenesis in camera type eye	GO:0060042	45	0.044
forebrain morphogenesis	GO:0048853	17	0.044
alcohol metabolic process	GO:0006066	116	0.044
oviduct epithelium development	GO:0035846	1	0.044
positive regulation of cell cycle	GO:0045787	92	0.044
positive regulation of mesonephros development	GO:0061213	20	0.043
acid secretion	GO:0046717	33	0.043
nephron tubule epithelial cell differentiation	GO:0072160	11	0.043
regulation of mesonephros development	GO:0061217	24	0.043
positive regulation of jak stat cascade	GO:0046427	22	0.043
cerebellar cortex development	GO:0021695	48	0.043
regulation of interferon gamma production	GO:0032649	57	0.043
regulation of lymphocyte activation	GO:0051249	240	0.042
dendrite development	GO:0016358	115	0.042
response to monosaccharide	GO:0034284	67	0.042
cellular response to acid chemical	GO:0071229	68	0.042
labyrinthine layer morphogenesis	GO:0060713	21	0.042	Mouse
camp metabolic process	GO:0046058	40	0.042
organic hydroxy compound transport	GO:0015850	93	0.041
adenohypophysis development	GO:0021984	14	0.041
positive regulation of growth hormone secretion	GO:0060124	3	0.041
regulation of cellular catabolic process	GO:0031329	242	0.041
cognition	GO:0050890	149	0.041
positive regulation of hormone secretion	GO:0046887	38	0.040
cellular response to peptide hormone stimulus	GO:0071375	92	0.040
mesoderm morphogenesis	GO:0048332	64	0.040
inner cell mass cell fate commitment	GO:0001827	2	0.040
inner medullary collecting duct development	GO:0072061	2	0.040
detection of abiotic stimulus	GO:0009582	60	0.040
inner ear receptor cell differentiation	GO:0060113	61	0.040
nucleobase containing small molecule metabolic process	GO:0055086	352	0.040
cardiac septum development	GO:0003279	59	0.040
bone mineralization	GO:0030282	54	0.040
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.040
glucose homeostasis	GO:0042593	128	0.040
sa node cell to atrial cardiac muscle cell signalling	GO:0086018	4	0.040
cation transmembrane transport	GO:0098655	266	0.039
regulation of cardioblast differentiation	GO:0051890	3	0.039
lens morphogenesis in camera type eye	GO:0002089	24	0.039
negative regulation of protein kinase b signaling	GO:0051898	18	0.039
regulation of organelle organization	GO:0033043	289	0.039
regulation of gliogenesis	GO:0014013	50	0.039
purkinje myocyte development	GO:0003165	1	0.039
cytokine mediated signaling pathway	GO:0019221	115	0.039
positive regulation of nervous system development	GO:0051962	221	0.039
interferon gamma production	GO:0032609	67	0.038
tyrosine phosphorylation of stat protein	GO:0007260	23	0.038
regulation of neuron death	GO:1901214	134	0.038
response to iron ion	GO:0010039	4	0.038
positive regulation of camp metabolic process	GO:0030816	19	0.038
morphogenesis of embryonic epithelium	GO:0016331	159	0.038
spinal cord motor neuron migration	GO:0097476	4	0.038
nephric duct formation	GO:0072179	4	0.037
lymphocyte apoptotic process	GO:0070227	54	0.037
regulation of tyrosine phosphorylation of stat protein	GO:0042509	20	0.037
negative regulation of gliogenesis	GO:0014014	23	0.037
tyrosine phosphorylation of stat3 protein	GO:0042503	12	0.037
embryonic skeletal system development	GO:0048706	120	0.037
embryonic placenta development	GO:0001892	98	0.037	Mouse
cell fate commitment involved in formation of primary germ layer	GO:0060795	26	0.036
regulation of tube size	GO:0035150	57	0.036
lung development	GO:0030324	164	0.036
trophectodermal cell differentiation	GO:0001829	21	0.036
adult locomotory behavior	GO:0008344	91	0.036
myelination	GO:0042552	74	0.036
metanephric nephron tubule development	GO:0072234	16	0.036
regulation of tyrosine phosphorylation of stat3 protein	GO:0042516	10	0.036
columnar cuboidal epithelial cell development	GO:0002066	29	0.036
autonomic nervous system development	GO:0048483	43	0.036
establishment of organ orientation	GO:0048561	1	0.036
calcium ion dependent exocytosis	GO:0017156	35	0.036
regulation of cardiac cell fate specification	GO:2000043	1	0.036

Prop1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of metabolism	DOID:0014667	0	0.073
	acquired metabolic disease	DOID:0060158	0	0.073

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network