IMP: Integrative Multi-species Prediction

Mus musculus

118 known processes

Psap

prosaposin

(Aliases: AI037048,SGP-1)

Ensembl: ENSMUSG00000004207
Entrez: 19156
UniProtKB: Q8BFQ1
UniProtKB: Q3TXJ0
UniProtKB: E9PZ00
UniProtKB: Q3UAS4
UniProtKB: Q61207
UniProtKB: B2RUD7
UniProtKB: Q3UE29
UniProtKB: Q3UFE8
UniProtKB: Q3TWM9

Process Predictions
Disease Predictions

Psap biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
vacuole organization	GO:0007033	38	0.745
cell type specific apoptotic process	GO:0097285	268	0.597
positive regulation of lymphocyte activation	GO:0051251	140	0.574
regulation of leukocyte proliferation	GO:0070663	121	0.564
copper ion homeostasis	GO:0055070	9	0.511
locomotory behavior	GO:0007626	195	0.491
cellular homeostasis	GO:0019725	240	0.464
endocytosis	GO:0006897	168	0.454
axonogenesis	GO:0007409	274	0.450
positive regulation of cell activation	GO:0050867	158	0.441
developmental maturation	GO:0021700	193	0.438
cellular amino acid metabolic process	GO:0006520	103	0.431
synapse organization	GO:0050808	125	0.412
cell adhesion	GO:0007155	329	0.395
cation homeostasis	GO:0055080	212	0.373
response to organic cyclic compound	GO:0014070	198	0.371
regulation of cell activation	GO:0050865	289	0.367
maintenance of location	GO:0051235	89	0.367
regulation of kinase activity	GO:0043549	249	0.363
neuromuscular process controlling balance	GO:0050885	59	0.358
organelle assembly	GO:0070925	177	0.349
regulation of transferase activity	GO:0051338	263	0.345
adult behavior	GO:0030534	135	0.342
negative regulation of neuron death	GO:1901215	98	0.333
cognition	GO:0050890	149	0.333
ion transmembrane transport	GO:0034220	361	0.330
regulation of lymphocyte activation	GO:0051249	240	0.327
skeletal system development	GO:0001501	356	0.321
male gamete generation	GO:0048232	285	0.320
regulation of angiotensin metabolic process	GO:0060177	4	0.319
macromolecule catabolic process	GO:0009057	281	0.308
neuron projection guidance	GO:0097485	141	0.301
apoptotic signaling pathway	GO:0097190	306	0.296
regulation of cellular component size	GO:0032535	121	0.293
cellular metal ion homeostasis	GO:0006875	151	0.287
regulation of acetylcholine secretion neurotransmission	GO:0014056	2	0.282
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.279
multicellular organismal homeostasis	GO:0048871	164	0.272
protein maturation	GO:0051604	176	0.271
sterol metabolic process	GO:0016125	58	0.270
actin cytoskeleton organization	GO:0030036	220	0.269
cellular ion homeostasis	GO:0006873	165	0.265
central nervous system neuron differentiation	GO:0021953	162	0.264
neuron death	GO:0070997	154	0.258
membrane organization	GO:0061024	245	0.258
chemotaxis	GO:0006935	247	0.257
dendrite development	GO:0016358	115	0.252
positive regulation of programmed cell death	GO:0043068	218	0.249
regulation of neuron death	GO:1901214	134	0.233
cell growth	GO:0016049	130	0.229
regulation of neuron differentiation	GO:0045664	281	0.223
nucleoside metabolic process	GO:0009116	246	0.222
neuron apoptotic process	GO:0051402	142	0.221
potassium ion transport	GO:0006813	52	0.220
intracellular protein transport	GO:0006886	204	0.215
purine nucleotide metabolic process	GO:0006163	302	0.214
axon guidance	GO:0007411	141	0.213
adult locomotory behavior	GO:0008344	91	0.208
renal system process	GO:0003014	48	0.205
protein catabolic process	GO:0030163	221	0.205
cellular modified amino acid metabolic process	GO:0006575	63	0.203
cation transport	GO:0006812	399	0.203
neuromuscular process	GO:0050905	99	0.200
sensory perception of sound	GO:0007605	97	0.200
regulation of actin filament based process	GO:0032970	99	0.198
sensory perception	GO:0007600	245	0.193
cellular chemical homeostasis	GO:0055082	215	0.192
acetylcholine transport	GO:0015870	2	0.183
lysosome organization	GO:0007040	21	0.182
meiotic cell cycle	GO:0051321	122	0.182
ribonucleotide metabolic process	GO:0009259	291	0.181
steroid metabolic process	GO:0008202	119	0.180
action potential	GO:0001508	78	0.180
carbohydrate metabolic process	GO:0005975	230	0.179
cellular copper ion homeostasis	GO:0006878	8	0.179
barbed end actin filament capping	GO:0051016	6	0.177
learning or memory	GO:0007611	148	0.174
regulation of neuron apoptotic process	GO:0043523	122	0.172
circadian sleep wake cycle rem sleep	GO:0042747	1	0.171
regulation of neuron projection development	GO:0010975	169	0.171
amine metabolic process	GO:0009308	45	0.168
regulation of blood pressure	GO:0008217	93	0.167
mitotic cell cycle	GO:0000278	195	0.167
multicellular organism growth	GO:0035264	161	0.165
t cell activation	GO:0042110	289	0.165
response to nutrient levels	GO:0031667	109	0.165
cellular protein complex assembly	GO:0043623	116	0.165
metal ion homeostasis	GO:0055065	189	0.162
microtubule based process	GO:0007017	236	0.161
regulation of t cell activation	GO:0050863	170	0.159
inorganic ion transmembrane transport	GO:0098660	234	0.158
inorganic cation transmembrane transport	GO:0098662	207	0.158
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.158
regulation of epidermal growth factor activated receptor activity	GO:0007176	7	0.155
negative regulation of protein metabolic process	GO:0051248	282	0.153
cellular response to hormone stimulus	GO:0032870	150	0.151
urinary bladder smooth muscle contraction	GO:0014832	5	0.151
actin filament bundle assembly	GO:0051017	40	0.149
regulation of cell adhesion	GO:0030155	154	0.149
muscle tissue development	GO:0060537	308	0.148
regulation of endopeptidase activity	GO:0052548	89	0.145
glycerolipid metabolic process	GO:0046486	122	0.144
associative learning	GO:0008306	61	0.144
male sex differentiation	GO:0046661	109	0.144
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.143
cellular amine metabolic process	GO:0044106	44	0.143
regulation of membrane potential	GO:0042391	192	0.142
calcium ion transport	GO:0006816	159	0.142
regulation of organelle organization	GO:0033043	289	0.142
organonitrogen compound catabolic process	GO:1901565	264	0.141
purine ribonucleotide metabolic process	GO:0009150	290	0.140
negative regulation of protein phosphorylation	GO:0001933	126	0.139
cation transmembrane transport	GO:0098655	266	0.137
sulfur compound metabolic process	GO:0006790	100	0.136
regulation of cell projection organization	GO:0031344	206	0.136
response to radiation	GO:0009314	165	0.135
muscle contraction	GO:0006936	101	0.134
renal system development	GO:0072001	225	0.134
nucleobase containing small molecule metabolic process	GO:0055086	352	0.133
actomyosin structure organization	GO:0031032	56	0.133
protein processing	GO:0016485	163	0.132
extrinsic apoptotic signaling pathway	GO:0097191	126	0.132
lipid localization	GO:0010876	126	0.128
acetylcholine secretion neurotransmission	GO:0014055	2	0.127
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.125
tissue remodeling	GO:0048771	102	0.125
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.124
tissue homeostasis	GO:0001894	115	0.123
regulation of protein kinase activity	GO:0045859	232	0.123
nucleoside phosphate metabolic process	GO:0006753	338	0.122
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.122
regulation of peptidase activity	GO:0052547	96	0.121
regulation of cellular catabolic process	GO:0031329	242	0.121
regulation of cellular amine metabolic process	GO:0033238	20	0.121
cell maturation	GO:0048469	127	0.120
negative regulation of protein serine threonine kinase activity	GO:0071901	49	0.120
learning	GO:0007612	98	0.119
regulation of hormone levels	GO:0010817	211	0.118
antigen processing and presentation of exogenous peptide antigen	GO:0002478	21	0.118
response to peptide	GO:1901652	136	0.114
purine containing compound metabolic process	GO:0072521	311	0.113
glycosyl compound catabolic process	GO:1901658	206	0.112
negative regulation of cell proliferation	GO:0008285	296	0.112
feeding behavior	GO:0007631	62	0.112
response to extracellular stimulus	GO:0009991	127	0.112
lymphocyte proliferation	GO:0046651	164	0.111
hindbrain morphogenesis	GO:0021575	46	0.110
response to organonitrogen compound	GO:0010243	246	0.110
regulation of cellular component biogenesis	GO:0044087	181	0.109
response to monosaccharide	GO:0034284	67	0.109
alcohol metabolic process	GO:0006066	116	0.109
divalent metal ion transport	GO:0070838	172	0.109
heterocycle catabolic process	GO:0046700	280	0.109
response to light stimulus	GO:0009416	135	0.108
regulation of homeostatic process	GO:0032844	182	0.107
organic cyclic compound catabolic process	GO:1901361	295	0.107
striated muscle tissue development	GO:0014706	293	0.106
synapse assembly	GO:0007416	56	0.105
b cell activation	GO:0042113	161	0.104
regulation of lymphocyte proliferation	GO:0050670	117	0.104
anatomical structure homeostasis	GO:0060249	145	0.104
kidney development	GO:0001822	213	0.103
nucleotide metabolic process	GO:0009117	332	0.100
muscle cell differentiation	GO:0042692	261	0.099
monosaccharide metabolic process	GO:0005996	106	0.098
positive regulation of apoptotic process	GO:0043065	217	0.097
circulatory system process	GO:0003013	197	0.097
transmembrane transport	GO:0055085	412	0.097
cellular lipid catabolic process	GO:0044242	52	0.097
regulation of actin cytoskeleton organization	GO:0032956	84	0.097
posttranscriptional regulation of gene expression	GO:0010608	155	0.096
spermatogenesis	GO:0007283	284	0.096
sphingolipid metabolic process	GO:0006665	45	0.096
cholesterol metabolic process	GO:0008203	56	0.096
visual behavior	GO:0007632	45	0.096
regulation of apoptotic signaling pathway	GO:2001233	197	0.096
cellular macromolecule catabolic process	GO:0044265	206	0.095
endomembrane system organization	GO:0010256	147	0.095
glycerophospholipid metabolic process	GO:0006650	71	0.094
regulation of vesicle mediated transport	GO:0060627	139	0.094
regulation of hydrolase activity	GO:0051336	246	0.094
protein lipid complex subunit organization	GO:0071825	12	0.093
autophagy	GO:0006914	45	0.093
nitrogen compound transport	GO:0071705	271	0.092
organic hydroxy compound metabolic process	GO:1901615	203	0.092
divalent inorganic cation transport	GO:0072511	178	0.092
regulation of proteolysis	GO:0030162	164	0.091
membrane protein proteolysis	GO:0033619	10	0.091
neuronal action potential	GO:0019228	54	0.091
regulation of angiotensin levels in blood	GO:0002002	4	0.091
multicellular organismal signaling	GO:0035637	91	0.089
oxidation reduction process	GO:0055114	342	0.088
development of primary sexual characteristics	GO:0045137	143	0.087
calcium ion homeostasis	GO:0055074	127	0.087
small gtpase mediated signal transduction	GO:0007264	97	0.086
leukocyte proliferation	GO:0070661	172	0.085
myeloid cell differentiation	GO:0030099	233	0.085
ear development	GO:0043583	200	0.084
generation of precursor metabolites and energy	GO:0006091	103	0.084
macroautophagy	GO:0016236	21	0.084
developmental growth involved in morphogenesis	GO:0060560	138	0.084
regulation of binding	GO:0051098	111	0.083
regulation of cytoskeleton organization	GO:0051493	122	0.083
urogenital system development	GO:0001655	261	0.082
cellular calcium ion homeostasis	GO:0006874	119	0.082
regulation of microtubule polymerization	GO:0031113	7	0.081
muscle system process	GO:0003012	141	0.081
carbohydrate derivative catabolic process	GO:1901136	231	0.081
cellular protein catabolic process	GO:0044257	155	0.080
skeletal muscle organ development	GO:0060538	163	0.080
rho protein signal transduction	GO:0007266	32	0.080
cerebellum morphogenesis	GO:0021587	42	0.079
pole plasm assembly	GO:0007315	2	0.078
regulation of anatomical structure size	GO:0090066	178	0.078
regulation of system process	GO:0044057	200	0.077
innate immune response	GO:0045087	157	0.076
homeostasis of number of cells	GO:0048872	210	0.075
negative regulation of neuron differentiation	GO:0045665	101	0.075
positive regulation of reactive oxygen species metabolic process	GO:2000379	11	0.075
ribose phosphate metabolic process	GO:0019693	291	0.075
peptide metabolic process	GO:0006518	46	0.075
cellular response to thyroid hormone stimulus	GO:0097067	1	0.074
regulation of defense response	GO:0031347	233	0.074
monocarboxylic acid metabolic process	GO:0032787	191	0.074
cellular component assembly involved in morphogenesis	GO:0010927	139	0.073
organic anion transport	GO:0015711	137	0.072
metencephalon development	GO:0022037	89	0.072
regulation of mapk cascade	GO:0043408	248	0.072
negative regulation of kinase activity	GO:0033673	81	0.072
negative regulation of molecular function	GO:0044092	258	0.071
negative regulation of growth	GO:0045926	99	0.071
ceramide metabolic process	GO:0006672	31	0.071
negative regulation of transferase activity	GO:0051348	85	0.071
sensory perception of mechanical stimulus	GO:0050954	107	0.070
skin development	GO:0043588	220	0.070
engulfment of apoptotic cell	GO:0043652	3	0.070
cellular response to antibiotic	GO:0071236	4	0.070
regulation of excitatory postsynaptic membrane potential	GO:0060079	41	0.070
hormone metabolic process	GO:0042445	86	0.069
response to thyroid hormone	GO:0097066	2	0.069
actin filament organization	GO:0007015	113	0.069
positive regulation of proteolysis	GO:0045862	85	0.069
antigen processing and presentation of peptide antigen	GO:0048002	29	0.069
cellular lipid metabolic process	GO:0044255	323	0.068
regulation of transmembrane transport	GO:0034762	128	0.068
erbb signaling pathway	GO:0038127	32	0.068
peptidyl tyrosine phosphorylation	GO:0018108	143	0.067
regulation of systemic arterial blood pressure	GO:0003073	61	0.067
negative regulation of cytokine production	GO:0001818	84	0.067
negative regulation of neuron apoptotic process	GO:0043524	92	0.067
muscle cell development	GO:0055001	133	0.065
cellular ketone metabolic process	GO:0042180	84	0.065
regulation of secretion	GO:0051046	274	0.065
cellular response to nutrient levels	GO:0031669	64	0.064
ribonucleoside metabolic process	GO:0009119	245	0.064
sensory perception of light stimulus	GO:0050953	54	0.064
blood circulation	GO:0008015	195	0.064
regulation of protein serine threonine kinase activity	GO:0071900	157	0.064
ribonucleoside catabolic process	GO:0042454	206	0.063
reactive oxygen species biosynthetic process	GO:1903409	8	0.063
cell recognition	GO:0008037	83	0.063
natural killer cell mediated cytotoxicity	GO:0042267	29	0.063
anion transport	GO:0006820	177	0.062
regulation of mitotic cell cycle	GO:0007346	126	0.062
organelle localization	GO:0051640	179	0.062
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.062
extracellular matrix organization	GO:0030198	147	0.062
multicellular organismal catabolic process	GO:0044243	7	0.062
forebrain development	GO:0030900	302	0.062
cerebellum development	GO:0021549	77	0.061
negative regulation of protein processing	GO:0010955	79	0.061
regulation of protein processing	GO:0070613	96	0.061
transition metal ion homeostasis	GO:0055076	54	0.061
rna polyadenylation	GO:0043631	6	0.060
positive regulation of t cell activation	GO:0050870	101	0.060
negative regulation of apoptotic signaling pathway	GO:2001234	104	0.060
negative regulation of intracellular signal transduction	GO:1902532	167	0.060
positive regulation of cell cycle	GO:0045787	92	0.059
negative regulation of cell cycle	GO:0045786	123	0.059
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.059
antigen processing and presentation of exogenous antigen	GO:0019884	26	0.059
negative regulation of blood vessel endothelial cell migration	GO:0043537	3	0.059
sensory organ morphogenesis	GO:0090596	242	0.059
cellular response to growth factor stimulus	GO:0071363	197	0.059
nucleoside monophosphate metabolic process	GO:0009123	85	0.059
heart contraction	GO:0060047	93	0.059
hormone mediated signaling pathway	GO:0009755	23	0.059
negative regulation of cell growth	GO:0030308	44	0.058
single organismal cell cell adhesion	GO:0016337	131	0.058
cellular response to external stimulus	GO:0071496	88	0.058
regulation of plasma lipoprotein particle levels	GO:0097006	23	0.057
negative regulation of epithelial cell proliferation	GO:0050680	64	0.057
cellular amide metabolic process	GO:0043603	58	0.057
meiotic cell cycle process	GO:1903046	77	0.057
regulation of protein complex assembly	GO:0043254	83	0.057
divalent inorganic cation homeostasis	GO:0072507	138	0.057
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.057
lipid modification	GO:0030258	65	0.057
regulation of metal ion transport	GO:0010959	106	0.056
autophagic vacuole assembly	GO:0000045	13	0.056
regulation of establishment of protein localization	GO:0070201	181	0.056
gland development	GO:0048732	330	0.055
regulation of protein localization	GO:0032880	231	0.055
regulation of purine nucleotide metabolic process	GO:1900542	169	0.055
regulation of microtubule based process	GO:0032886	52	0.055
positive regulation of innate immune response	GO:0045089	80	0.055
response to oxidative stress	GO:0006979	123	0.055
extrinsic apoptotic signaling pathway in absence of ligand	GO:0097192	55	0.054
ras protein signal transduction	GO:0007265	77	0.053
inflammatory response	GO:0006954	244	0.053
positive regulation of membrane protein ectodomain proteolysis	GO:0051044	3	0.053
microtubule cytoskeleton organization	GO:0000226	157	0.053
developmental cell growth	GO:0048588	84	0.052
positive regulation of neuron projection development	GO:0010976	79	0.052
positive regulation of cell death	GO:0010942	224	0.052
epithelial cell proliferation	GO:0050673	174	0.052
memory	GO:0007613	58	0.052
male gonad development	GO:0008584	88	0.052
circadian rhythm	GO:0007623	114	0.052
rna 3 end processing	GO:0031123	20	0.052
multicellular organismal response to stress	GO:0033555	62	0.051
sphingolipid catabolic process	GO:0030149	7	0.051
positive regulation of leukocyte differentiation	GO:1902107	86	0.051
response to interleukin 4	GO:0070670	23	0.051
multi multicellular organism process	GO:0044706	109	0.051
small molecule catabolic process	GO:0044282	71	0.051
regulation of cytokine production	GO:0001817	266	0.051
regulation of cellular ketone metabolic process	GO:0010565	66	0.051
adult walking behavior	GO:0007628	41	0.050
positive regulation of transferase activity	GO:0051347	167	0.050
hexose metabolic process	GO:0019318	98	0.050
positive regulation of protein export from nucleus	GO:0046827	4	0.050
lytic vacuole organization	GO:0080171	21	0.050
reactive oxygen species metabolic process	GO:0072593	84	0.050
regulation of cell cycle	GO:0051726	281	0.050
regulation of ion transport	GO:0043269	215	0.049
negative regulation of peptidase activity	GO:0010466	46	0.049
negative regulation of nervous system development	GO:0051961	156	0.049
carbohydrate homeostasis	GO:0033500	128	0.048
bone development	GO:0060348	120	0.048
purine nucleoside metabolic process	GO:0042278	241	0.048
protein polymerization	GO:0051258	57	0.048
positive regulation of inflammatory response	GO:0050729	47	0.048
positive regulation of growth	GO:0045927	104	0.048
regulation of leukocyte differentiation	GO:1902105	159	0.047
lymphocyte differentiation	GO:0030098	242	0.047
regulation of extrinsic apoptotic signaling pathway	GO:2001236	77	0.047
visual learning	GO:0008542	44	0.047
cholesterol homeostasis	GO:0042632	44	0.047
cytoplasmic transport	GO:0016482	234	0.047
carbohydrate catabolic process	GO:0016052	32	0.047
response to alcohol	GO:0097305	48	0.046
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.046
cellular pigmentation	GO:0033059	20	0.046
regulation of inflammatory response	GO:0050727	147	0.046
transmission of nerve impulse	GO:0019226	76	0.046
lipid storage	GO:0019915	36	0.046
calcium ion transmembrane transport	GO:0070588	85	0.045
regulation of body fluid levels	GO:0050878	162	0.045
negative regulation of cellular component organization	GO:0051129	194	0.045
regulation of protein binding	GO:0043393	60	0.045
bone resorption	GO:0045453	38	0.045
long term memory	GO:0007616	15	0.045
gonad development	GO:0008406	141	0.045
anion homeostasis	GO:0055081	16	0.045
fertilization	GO:0009566	127	0.045
beta amyloid clearance	GO:0097242	2	0.044
sterol homeostasis	GO:0055092	45	0.044
vesicle organization	GO:0016050	60	0.044
cellular response to extracellular stimulus	GO:0031668	81	0.044
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.044
carboxylic acid transport	GO:0046942	100	0.044
regulation of cell growth	GO:0001558	91	0.044
regulation of leukocyte mediated immunity	GO:0002703	104	0.044
regulation of cellular amino acid metabolic process	GO:0006521	5	0.044
actin polymerization or depolymerization	GO:0008154	54	0.044
cellular response to glucose stimulus	GO:0071333	45	0.044
epidermal growth factor receptor signaling pathway	GO:0007173	28	0.044
protein oligomerization	GO:0051259	67	0.043
plasma membrane organization	GO:0007009	90	0.043
forebrain radial glial cell differentiation	GO:0021861	4	0.043
inner ear receptor cell differentiation	GO:0060113	61	0.043
development of primary male sexual characteristics	GO:0046546	88	0.043
protein import	GO:0017038	101	0.042
hindbrain development	GO:0030902	128	0.042
cellular potassium ion transport	GO:0071804	43	0.042
synaptic growth at neuromuscular junction	GO:0051124	6	0.042
negative regulation of protein modification process	GO:0031400	163	0.042
organophosphate biosynthetic process	GO:0090407	122	0.041
negative regulation of endothelial cell migration	GO:0010596	4	0.041
glycosyl compound metabolic process	GO:1901657	246	0.041
positive regulation of protein serine threonine kinase activity	GO:0071902	106	0.041
negative regulation of cellular protein metabolic process	GO:0032269	247	0.041
heart morphogenesis	GO:0003007	178	0.040
cell cycle arrest	GO:0007050	37	0.040
smooth muscle contraction involved in micturition	GO:0060083	3	0.040
cellular response to cytokine stimulus	GO:0071345	189	0.040
cellular carbohydrate metabolic process	GO:0044262	119	0.040
regulation of myeloid cell differentiation	GO:0045637	96	0.040
regulation of intracellular protein transport	GO:0033157	82	0.040
nucleoside catabolic process	GO:0009164	206	0.040
positive regulation of response to wounding	GO:1903036	66	0.039
regulation of protein stability	GO:0031647	52	0.039
triglyceride metabolic process	GO:0006641	51	0.038
regulation of ion transmembrane transport	GO:0034765	119	0.037
alpha amino acid metabolic process	GO:1901605	59	0.037
establishment or maintenance of cytoskeleton polarity	GO:0030952	2	0.037
chondrocyte differentiation	GO:0002062	72	0.037
single organism cell adhesion	GO:0098602	156	0.037
nucleocytoplasmic transport	GO:0006913	139	0.037
regulation of feeding behavior	GO:0060259	3	0.037
regulation of inclusion body assembly	GO:0090083	1	0.037
positive regulation of kinase activity	GO:0033674	155	0.037
regulation of calcium ion transport	GO:0051924	69	0.037
striated muscle cell development	GO:0055002	125	0.037
dna metabolic process	GO:0006259	303	0.036
regulation of exocytosis	GO:0017157	61	0.036
germ cell development	GO:0007281	185	0.036
pigment granule localization	GO:0051875	13	0.036
central nervous system neuron development	GO:0021954	67	0.036
regulation of endocytosis	GO:0030100	69	0.036
microtubule based movement	GO:0007018	84	0.036
organelle fission	GO:0048285	170	0.036
protein targeting	GO:0006605	143	0.036
organophosphate catabolic process	GO:0046434	232	0.036
negative regulation of phosphorylation	GO:0042326	166	0.036
cartilage development	GO:0051216	140	0.036
calcium mediated signaling	GO:0019722	46	0.036
regulation of actin filament length	GO:0030832	45	0.036
glial cell differentiation	GO:0010001	131	0.035
response to starvation	GO:0042594	65	0.035
glucose homeostasis	GO:0042593	128	0.035
regulation of reactive oxygen species biosynthetic process	GO:1903426	2	0.035
regulation of beta amyloid clearance	GO:1900221	1	0.035
nucleoside phosphate catabolic process	GO:1901292	222	0.035
ionotropic glutamate receptor signaling pathway	GO:0035235	29	0.035
membrane lipid metabolic process	GO:0006643	53	0.034
epidermis development	GO:0008544	187	0.034
locomotor rhythm	GO:0045475	8	0.034
exocytosis	GO:0006887	121	0.034
positive regulation of homeostatic process	GO:0032846	64	0.034
positive regulation of extrinsic apoptotic signaling pathway	GO:2001238	34	0.034
positive regulation of cellular component biogenesis	GO:0044089	94	0.034
extracellular structure organization	GO:0043062	148	0.034
sperm motility	GO:0030317	47	0.034
negative regulation of cellular amide metabolic process	GO:0034249	4	0.034
detection of abiotic stimulus	GO:0009582	60	0.034
auditory receptor cell differentiation	GO:0042491	37	0.033
regulation of secretion by cell	GO:1903530	249	0.033
response to oxygen levels	GO:0070482	62	0.033
aromatic compound catabolic process	GO:0019439	286	0.033
regulation of synapse assembly	GO:0051963	29	0.033
b cell proliferation	GO:0042100	53	0.033
negative regulation of cell projection organization	GO:0031345	56	0.033
phagocytosis	GO:0006909	66	0.033
positive regulation of secretion by cell	GO:1903532	114	0.033
glycolipid metabolic process	GO:0006664	25	0.033
myeloid cell homeostasis	GO:0002262	114	0.033
regulation of b cell activation	GO:0050864	81	0.032
microglia development	GO:0014005	2	0.032
regulation of neurotransmitter secretion	GO:0046928	29	0.032
insulin secretion involved in cellular response to glucose stimulus	GO:0035773	36	0.032
carbohydrate derivative biosynthetic process	GO:1901137	183	0.032
lipid catabolic process	GO:0016042	69	0.032
regulation of intracellular transport	GO:0032386	159	0.031
conditioned taste aversion	GO:0001661	4	0.031
regulation of lymphocyte mediated immunity	GO:0002706	84	0.031
high density lipoprotein particle assembly	GO:0034380	3	0.031
regulation of protein maturation	GO:1903317	96	0.031
positive regulation of mapk cascade	GO:0043410	170	0.031
purine nucleoside catabolic process	GO:0006152	205	0.031
molting cycle	GO:0042303	90	0.031
lateral line system development	GO:0048925	1	0.031
establishment of protein localization to organelle	GO:0072594	118	0.031
regulation of epithelial cell proliferation	GO:0050678	141	0.031
purine nucleotide catabolic process	GO:0006195	211	0.030

Psap disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability	Func Analog Org
disease of metabolism	DOID:0014667	0.832	Human
lipid storage disease	DOID:9455	0.832	Human
lysosomal storage disease	DOID:3211	0.832	Human
inherited metabolic disorder	DOID:655	0.832	Human
central nervous system disease	DOID:331	0.162	Human
disease of anatomical entity	DOID:7	0.162	Human
nervous system disease	DOID:863	0.162	Human
sphingolipidosis	DOID:1927	0.155	Human
neuronal ceroid lipofuscinosis	DOID:14503	0.100
immune system disease	DOID:2914	0.068
lymphatic system disease	DOID:75	0.068
acquired metabolic disease	DOID:0060158	0.060
musculoskeletal system disease	DOID:17	0.058
connective tissue disease	DOID:65	0.058
brain disease	DOID:936	0.051	Human
dementia	DOID:1307	0.049
alzheimer s disease	DOID:10652	0.049
disease of mental health	DOID:150	0.049
tauopathy	DOID:680	0.049
neurodegenerative disease	DOID:1289	0.049
cognitive disorder	DOID:1561	0.049

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