Mus musculus

199 known processes

Ptch1

patched homolog 1

(Aliases: Ptc1,A230106A15Rik,Ptc,mes,Ptch)

Ptch1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regionalizationGO:00030023370.999
branching morphogenesis of an epithelial tubeGO:00487541590.996
hindlimb morphogenesisGO:0035137420.992
spinal cord motor neuron differentiationGO:0021522350.982
nodal signaling pathway involved in determination of left right asymmetryGO:003810720.981
stem cell proliferationGO:00720891170.979
regulation of smoothened signaling pathwayGO:0008589580.970
appendage developmentGO:00487361660.969
positive regulation of epithelial cell proliferation involved in lung morphogenesisGO:006050130.969
neural tube closureGO:0001843900.969
embryonic skeletal system developmentGO:00487061200.966
smoothened signaling pathway involved in dorsal ventral neural tube patterningGO:0060831120.965
osteoblast developmentGO:0002076170.964
neural tube patterningGO:0021532430.963
epithelial tube morphogenesisGO:00605623030.962
negative regulation of cell proliferationGO:00082852960.962
response to sterolGO:003631440.958
embryonic skeletal system morphogenesisGO:0048704910.957
formation of radial glial scaffoldsGO:002194340.954
skeletal system developmentGO:00015013560.953
embryonic organ morphogenesisGO:00485622760.948
regulation of astrocyte differentiationGO:0048710200.948
gland developmentGO:00487323300.941
smoothened signaling pathwayGO:00072241050.940
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetryGO:190016420.934
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesisGO:007203940.929
positive regulation of bmp signaling pathwayGO:0030513230.927
germ line stem cell divisionGO:004207820.926
actin cytoskeleton organizationGO:00300362200.921
chondrocyte differentiationGO:0002062720.921
epithelial tube formationGO:00721751300.920
floor plate morphogenesisGO:003350530.918
nephrogenic mesenchyme morphogenesisGO:007213420.912
morphogenesis of a branching structureGO:00017632030.912
positive regulation of cell deathGO:00109422240.908
neural tube developmentGO:00219151600.907
endodermal cell fate specificationGO:000171440.905
heart morphogenesisGO:00030071780.904
rhythmic processGO:00485111740.902
angiogenesisGO:00015252010.900
forebrain radial glial cell differentiationGO:002186140.900
camera type eye developmentGO:00430102660.894
Zebrafish
stem cell developmentGO:00488642190.891
stem cell maintenanceGO:00198271300.886
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulusGO:190152270.886
central nervous system neuron differentiationGO:00219531620.882
somite developmentGO:0061053810.881
metanephric mesenchyme morphogenesisGO:007213340.879
planar cell polarity pathway involved in cardiac muscle tissue morphogenesisGO:006135020.876
cardiac endothelial cell differentiationGO:000334840.872
regulation of cardiac muscle tissue developmentGO:0055024310.870
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetryGO:190009420.867
regulation of cell morphogenesis involved in differentiationGO:00107691510.866
negative regulation of cell cycleGO:00457861230.862
positive regulation of cell proliferation involved in heart valve morphogenesisGO:000325110.857
embryonic skeletal joint morphogenesisGO:0060272110.857
oocyte axis specificationGO:000730920.855
negative regulation of glial cell differentiationGO:0045686210.835
mammary gland epithelium developmentGO:0061180650.833
negative regulation of protein modification processGO:00314001630.832
regulation of kinase activityGO:00435492490.829
mesonephric tubule developmentGO:0072164940.825
ureteric bud morphogenesisGO:0060675620.823
negative regulation of cell fate specificationGO:000999640.819
neural tube formationGO:00018411080.818
kidney epithelium developmentGO:00720731210.809
muscle cell fate specificationGO:004269410.807
telencephalon developmentGO:00215371860.802
regulation of protein transportGO:00512231630.801
Fly
axial mesodermal cell fate commitmentGO:004832210.800
negative regulation of smoothened signaling pathwayGO:0045879250.799
mesenchymal cell apoptotic process involved in nephron morphogenesisGO:190114540.793
regulation of planar cell polarity pathway involved in ventricular septum morphogenesisGO:200014810.789
negative regulation of planar cell polarity pathway involved in pericardium morphogenesisGO:200016610.789
negative regulation of bmp signaling pathwayGO:0030514350.788
regulation of mitotic cell cycleGO:00073461260.788
primary neural tube formationGO:0014020950.779
homeostasis of number of cellsGO:00488722100.773
neuron projection guidanceGO:00974851410.770
Fly
wnt signaling pathway involved in forebrain neuroblast divisionGO:002187420.769
negative regulation of molecular functionGO:00440922580.767
lung developmentGO:00303241640.766
negative regulation of astrocyte differentiationGO:0048712100.763
cellular response to cholesterolGO:007139720.763
negative regulation of protein serine threonine kinase activityGO:0071901490.760
mesenchyme developmentGO:00604851520.754
carbon catabolite activation of transcription from rna polymerase ii promoterGO:000043640.753
embryonic epithelial tube formationGO:00018381300.751
negative regulation of mitotic cell cycleGO:0045930580.741
negative regulation of lymphocyte differentiationGO:0045620320.740
negative regulation of glial cell proliferationGO:006025340.735
cellular ketone metabolic processGO:0042180840.731
protein localization to nucleusGO:00345041210.725
Fly
regulation of cardiac cell fate specificationGO:200004310.723
pallium developmentGO:00215431200.720
retinal ganglion cell axon guidanceGO:0031290180.715
gastrulationGO:00073691160.713
smoothened signaling pathway involved in ventral spinal cord patterningGO:002191070.710
positive regulation of apoptotic signaling pathwayGO:2001235950.709
ventricular zone neuroblast divisionGO:002184730.709
germ cell developmentGO:00072811850.707
Worm Fly
negative regulation of transcription involved in g1 s transition of mitotic cell cycleGO:007193010.706
inner ear receptor cell differentiationGO:0060113610.704
oocyte differentiationGO:0009994350.698
regulation of cellular amino acid metabolic processGO:000652150.698
lymphocyte differentiationGO:00300982420.697
negative regulation of protein metabolic processGO:00512482820.694
mesenchymal cell proliferationGO:0010463440.693
cellular response to lipidGO:00713961450.692
regulation of protein targetingGO:1903533610.691
Fly
bone morphogenesisGO:0060349780.689
carbon catabolite activation of transcriptionGO:004599140.687
mammary gland morphogenesisGO:0060443540.685
smooth muscle tissue developmentGO:0048745220.683
trophectodermal cellular morphogenesisGO:000183130.675
somatic stem cell maintenanceGO:0035019470.674
regulation of protein kinase activityGO:00458592320.673
kidney developmentGO:00018222130.672
nephron morphogenesisGO:0072028690.670
muscle cell differentiationGO:00426922610.667
positive regulation of programmed cell deathGO:00430682180.666
regulation of cell migrationGO:00303342190.654
Fly
negative regulation of stem cell maintenanceGO:190245540.654
connective tissue developmentGO:00614481790.654
positive regulation of apoptotic processGO:00430652170.649
respiratory system developmentGO:00605411900.648
Fly
negative regulation of leukocyte differentiationGO:1902106510.646
negative regulation of prostatic bud formationGO:006068640.643
columnar cuboidal epithelial cell differentiationGO:0002065820.643
regulation of establishment of protein localizationGO:00702011810.636
Fly
establishment or maintenance of neuroblast polarityGO:004519610.635
leukocyte differentiationGO:00025213420.634
dorsal ventral neural tube patterningGO:0021904280.633
embryonic skeletal joint developmentGO:0072498130.631
dna metabolic processGO:00062593030.631
regulation of apoptotic signaling pathwayGO:20012331970.627
ossificationGO:00015032160.625
Zebrafish
neural precursor cell proliferationGO:00613511210.624
leukocyte proliferationGO:00706611720.624
positive regulation of protein serine threonine kinase activityGO:00719021060.618
negative regulation of epithelial cell proliferationGO:0050680640.618
spermatogenesisGO:00072832840.616
regulation of cell cycleGO:00517262810.616
branching involved in ureteric bud morphogenesisGO:0001658560.614
morphogenesis of embryonic epitheliumGO:00163311590.612
somitogenesisGO:0001756690.610
negative regulation of kinase activityGO:0033673810.608
regulation of mapk cascadeGO:00434082480.607
protein processingGO:00164851630.605
regulation of somitogenesisGO:001480760.604
regulation of cellular component biogenesisGO:00440871810.603
negative regulation of cell developmentGO:00107211690.603
skeletal system morphogenesisGO:00487052030.596
astrocyte differentiationGO:0048708430.593
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573690.589
axonogenesisGO:00074092740.577
Fly
regulation of glial cell differentiationGO:0045685410.573
regulation of cytoskeleton organizationGO:00514931220.571
carbon catabolite repression of transcription from rna polymerase ii promoterGO:000043710.571
chondrocyte developmentGO:0002063240.567
somite specificationGO:000175740.566
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.563
cardiac right atrium morphogenesisGO:000321330.561
auditory receptor cell fate determinationGO:004266830.559
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296820.555
morphogenesis of a branching epitheliumGO:00611381930.554
transforming growth factor beta receptor signaling pathway involved in primitive streak formationGO:009001010.548
axis elongation involved in somitogenesisGO:009024540.548
cellular macromolecule catabolic processGO:00442652060.548
regulation of planar cell polarity pathway involved in outflow tract morphogenesisGO:200016310.545
regulation of stem cell differentiationGO:2000736500.543
bmp signaling pathwayGO:0030509930.541
cellular amine metabolic processGO:0044106440.540
cellular response to organic cyclic compoundGO:0071407870.540
sensory perceptionGO:00076002450.539
axon guidanceGO:00074111410.538
Fly
forebrain morphogenesisGO:0048853170.531
cell type specific apoptotic processGO:00972852680.529
negative regulation of protein phosphorylationGO:00019331260.529
positive regulation of epithelial to mesenchymal transitionGO:0010718130.527
nuclear transportGO:00511691390.526
Fly
forebrain developmentGO:00309003020.526
regulation of endodermal cell fate specificationGO:004266320.525
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.522
cerebral cortex radial glia guided migrationGO:0021801170.518
protein maturationGO:00516041760.517
male gamete generationGO:00482322850.508
trachea formationGO:006044030.505
negative regulation of cardiac muscle tissue developmentGO:005502680.504
mesenchymal cell developmentGO:0014031930.502
positive regulation of kinase activityGO:00336741550.501
ovulation cycleGO:0042698590.500
myeloid leukocyte differentiationGO:00025731190.499
negative regulation of growthGO:0045926990.498
roof plate formationGO:002150910.497
negative regulation of t cell differentiationGO:0045581230.496
epithelial tube branching involved in lung morphogenesisGO:0060441280.496
blood vessel morphogenesisGO:00485142850.489
forebrain generation of neuronsGO:0021872630.489
negative regulation of planar cell polarity pathway involved in heart morphogenesisGO:200016010.488
nuclear importGO:0051170950.488
Fly
positive regulation of cellular amine metabolic processGO:003324050.488
ureteric bud developmentGO:0001657940.483
negative regulation of photoreceptor cell differentiationGO:004653340.482
endothelial cell differentiationGO:0045446410.479
positive regulation of immature t cell proliferationGO:003309140.479
protein targetingGO:00066051430.476
Fly
regulation of actin cytoskeleton organizationGO:0032956840.475
negative regulation of lymphocyte activationGO:0051250910.472
brain morphogenesisGO:0048854320.472
multicellular organism growthGO:00352641610.467
embryonic limb morphogenesisGO:00303261260.465
kidney morphogenesisGO:0060993830.465
negative regulation of phosphorylationGO:00423261660.465
endocardial cell differentiationGO:006095640.464
positive regulation of neuron deathGO:1901216280.463
cellular response to growth factor stimulusGO:00713631970.462
aorta morphogenesisGO:0035909220.460
small gtpase mediated signal transductionGO:0007264970.458
tube closureGO:0060606910.454
renal tubule developmentGO:0061326870.454
positive regulation of alpha beta t cell differentiationGO:0046638280.448
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.447
regulation of synaptic growth at neuromuscular junctionGO:000858240.443
carbon catabolite regulation of transcriptionGO:004599040.441
embryonic heart tube morphogenesisGO:0003143510.440
lung morphogenesisGO:0060425500.438
tube formationGO:00351481400.435
negative regulation of neuron differentiationGO:00456651010.431
mesenchymal cell differentiationGO:00487621070.426
regulation of sequence specific dna binding transcription factor activityGO:00510901060.425
positive regulation of leukocyte differentiationGO:1902107860.422
regulation of smooth muscle cell differentiationGO:005115090.421
spinal cord ventral commissure morphogenesisGO:002196520.419
platelet derived growth factor receptor alpha signaling pathwayGO:003579030.419
negative regulation of immature t cell proliferationGO:003308730.415
respiratory tube developmentGO:00303231670.415
regulation of organelle organizationGO:00330432890.414
regulation of transferase activityGO:00513382630.414
regulation of endodermal cell differentiationGO:190322420.413
nephron tubule developmentGO:0072080840.413
muscle tissue developmentGO:00605373080.411
hippocampus developmentGO:0021766520.409
regulation of neuron projection developmentGO:00109751690.409
negative regulation of cellular protein metabolic processGO:00322692470.408
regulation of cell motilityGO:20001452360.407
Fly
anterior commissure morphogenesisGO:002196060.407
epithelial cell proliferationGO:00506731740.406
positive regulation of transcription from rna polymerase ii promoter by glucoseGO:000043230.404
developmental maturationGO:00217001930.404
ubiquitin dependent protein catabolic processGO:00065111290.404
cerebellum developmentGO:0021549770.404
regulation of canonical wnt signaling pathwayGO:0060828820.404
regulation of cellular amine metabolic processGO:0033238200.402
muscle cell developmentGO:00550011330.400
regulation of protein localizationGO:00328802310.397
organelle assemblyGO:00709251770.395
positive regulation of hh target transcription factor activityGO:000722830.395
negative regulation of gliogenesisGO:0014014230.394
regulation of endothelial cell differentiationGO:0045601100.394
regulation of bmp signaling pathwayGO:0030510600.394
molting cycleGO:0042303900.390
Mouse Worm
mesenchyme morphogenesisGO:0072132320.390
digestive tract morphogenesisGO:00485461470.389
regulation of neuron differentiationGO:00456642810.388
regulation of intracellular protein transportGO:0033157820.385
Fly
appendage morphogenesisGO:00351071490.383
cell fate commitmentGO:00451652100.383
Fly
negative regulation of map kinase activityGO:0043407340.380
carbohydrate homeostasisGO:00335001280.380
stem cell differentiationGO:00488632680.379
Zebrafish
prostate gland morphogenesisGO:0060512320.379
positive regulation of mesenchymal cell proliferationGO:0002053330.379
regulation of leukocyte differentiationGO:19021051590.373
glomerulus morphogenesisGO:0072102100.373
positive regulation of growthGO:00459271040.373
Worm
lateral mesodermal cell differentiationGO:004837130.372
regulation of tendon cell differentiationGO:200104910.372
metanephros developmentGO:0001656790.370
formation of anatomical boundaryGO:004885960.368
cytoplasmic transportGO:00164822340.366
Fly
positive regulation of actin filament bundle assemblyGO:0032233110.355
kidney mesenchyme developmentGO:0072074140.355
regulation of protein import into nucleusGO:0042306520.352
Fly
cell differentiation in spinal cordGO:0021515530.352
glycosyl compound metabolic processGO:19016572460.351
cell proliferation involved in metanephros developmentGO:007220390.351
negative regulation of cell activationGO:00508661110.351
regulation of nucleocytoplasmic transportGO:0046822730.348
Fly
signal transduction by p53 class mediatorGO:0072331510.345
endodermal cell fate determinationGO:000749320.344
epithelial cell maturation involved in prostate gland developmentGO:006074340.342
positive regulation of transferase activityGO:00513471670.340
regulation of cytoplasmic transportGO:19036491120.339
Fly
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.339
regulation of protein stabilityGO:0031647520.337
notch signaling pathwayGO:0007219710.335
urogenital system developmentGO:00016552610.333
somatic sex determinationGO:001899320.332
regulation of cell projection organizationGO:00313442060.332
positive regulation of protein modification processGO:00314012990.331
central nervous system neuron developmentGO:0021954670.330
neural crest cell migrationGO:0001755320.329
diencephalon developmentGO:0021536630.329
regulation of myoblast differentiationGO:0045661290.327
mesodermal cell fate determinationGO:000750010.324
digestive tract developmentGO:00485651900.324
regulation of g1 s transition of mitotic cell cycleGO:2000045350.321
peptidyl tyrosine modificationGO:00182121450.320
positive regulation of cartilage developmentGO:0061036180.320
ras protein signal transductionGO:0007265770.319
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesisGO:200014910.318
morphogenesis of an epithelial budGO:0060572180.318
jak stat cascadeGO:0007259420.318
cardiac cell developmentGO:0055006410.317
negative regulation of cellular amine metabolic processGO:003323910.314
positive regulation of ossificationGO:0045778470.311
cell proliferation involved in heart valve morphogenesisGO:000324910.309
regulation of anatomical structure sizeGO:00900661780.308
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferationGO:002193840.305
cell divisionGO:00513011200.305
epithelial cell proliferation involved in prostate gland developmentGO:0060767110.305
retina development in camera type eyeGO:00600411190.304
Zebrafish
negative regulation of reproductive processGO:2000242310.304
epithelial to mesenchymal transitionGO:0001837470.303
cellular component assembly involved in morphogenesisGO:00109271390.303
inner cell mass cellular morphogenesisGO:000182810.303
cerebellar granule cell precursor proliferationGO:0021930100.300
morphogenesis of an epithelial foldGO:0060571280.300
regulation of mitotic cell cycle phase transitionGO:1901990730.300
protein catabolic processGO:00301632210.297
t cell activationGO:00421102890.297
wnt signaling pathway involved in somitogenesisGO:009024440.297
sensory organ morphogenesisGO:00905962420.296
Zebrafish Fly
thyroid stimulating hormone secreting cell differentiationGO:006012940.295
positive regulation of epithelial cell proliferationGO:0050679680.294
peptidyl tyrosine phosphorylationGO:00181081430.293
single organismal cell cell adhesionGO:00163371310.292
pyramidal neuron migrationGO:002185210.292
glomerulus vasculature morphogenesisGO:007210360.292
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesisGO:007204040.290
g1 s transition of mitotic cell cycleGO:0000082570.290
ureter morphogenesisGO:007219740.289
response to nutrient levelsGO:00316671090.289
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.289
protein modification by small protein conjugation or removalGO:00706472070.288
cell migration involved in coronary angiogenesisGO:006098110.287
forebrain ventricular zone progenitor cell divisionGO:002186960.287
nephron developmentGO:00720061090.284
mesonephros developmentGO:0001823970.284
regulation of cell cycle processGO:00105641600.279
regulation of dna replicationGO:0006275170.279
regulation of smad protein import into nucleusGO:006039030.278
spinal cord developmentGO:0021510810.277
ascending aorta morphogenesisGO:003591030.276
positive regulation of cell migrationGO:00303351090.275
lipid homeostasisGO:0055088630.275
Fly
heart field specificationGO:000312860.274
canonical wnt signaling pathwayGO:00600701300.272
regulation of vasculature developmentGO:1901342880.272
positive regulation of neuron apoptotic processGO:0043525250.272
posttranscriptional regulation of gene expressionGO:00106081550.270
guanosine containing compound metabolic processGO:19010681440.270
purine nucleoside metabolic processGO:00422782410.269
mammary gland specificationGO:006059440.269
negative regulation of transferase activityGO:0051348850.269
regulation of transcription involved in primary germ layer cell fate commitmentGO:006079620.269
embryonic heart tube anterior posterior pattern specificationGO:003505430.267
canonical wnt signaling pathway involved in negative regulation of apoptotic processGO:004433640.267
epidermis developmentGO:00085441870.266
rho protein signal transductionGO:0007266320.266
meiotic cell cycleGO:00513211220.265
glomerular capillary formationGO:007210460.265
regulation of neuron deathGO:19012141340.263
positive regulation of chondrocyte differentiationGO:0032332130.263
glomerulus vasculature developmentGO:0072012140.261
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.261
apoptotic signaling pathwayGO:00971903060.258
regulation of cellular catabolic processGO:00313292420.258
forebrain neuron differentiationGO:0021879520.257
regulation of hydrolase activityGO:00513362460.257
cloacal septationGO:006019720.257
ear morphogenesisGO:00424711180.255
regulation of bindingGO:00510981110.254
radial glial cell differentiationGO:006001960.254
limb developmentGO:00601731660.252
negative regulation of wnt signaling pathway involved in heart developmentGO:000330840.252
negative regulation of t cell activationGO:0050868650.252
regulation of ras protein signal transductionGO:00465781140.251
metanephric glomerular mesangium developmentGO:007222330.251
negative regulation of dendritic spine developmentGO:006100030.250
hypophysis morphogenesisGO:004885030.249
carbon catabolite regulation of transcription from rna polymerase ii promoterGO:000042940.248
kidney mesenchyme morphogenesisGO:007213140.248
pituitary gland developmentGO:0021983380.248
regulation of t cell differentiation in thymusGO:0033081240.247
planar cell polarity pathway involved in pericardium morphogenesisGO:006135420.247
regulation of tyrosine phosphorylation of stat1 proteinGO:004251020.247
organelle fissionGO:00482851700.247
cell proliferation in midbrainGO:003327820.247
chemotaxisGO:00069352470.246
Fly
regulation of alpha beta t cell differentiationGO:0046637350.246
ear developmentGO:00435832000.245
positive regulation of lens epithelial cell proliferationGO:200111110.244
cardiocyte differentiationGO:0035051870.244
Zebrafish
positive regulation of nervous system developmentGO:00519622210.244
hindbrain developmentGO:00309021280.243
dendrite developmentGO:00163581150.242
face morphogenesisGO:0060325290.242
mesonephric epithelium developmentGO:0072163940.242
regulation of cellular response to growth factor stimulusGO:0090287820.241
regulation of t cell differentiationGO:0045580830.241
orbitofrontal cortex developmentGO:002176920.241
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.241
organ growthGO:00352651170.240
foregut morphogenesisGO:0007440120.239
heterocycle catabolic processGO:00467002800.239
actomyosin structure organizationGO:0031032560.237
response to cholesterolGO:007072340.237
skin developmentGO:00435882200.235
regulation of intracellular transportGO:00323861590.235
Fly
digestive system developmentGO:00551232000.233
midbrain hindbrain boundary morphogenesisGO:002155540.233
metanephric nephron tubule formationGO:007228940.233
ribonucleoside catabolic processGO:00424542060.232
cellular response to dna damage stimulusGO:00069742070.232
ribonucleoside metabolic processGO:00091192450.232
rostrocaudal neural tube patterningGO:0021903120.232
nucleoside triphosphate metabolic processGO:00091412300.231
protein import into nucleusGO:0006606950.231
Fly
epithelial cell developmentGO:00020641590.230
liver developmentGO:0001889660.227
negative regulation of nervous system developmentGO:00519611560.226
renal vesicle inductionGO:007203430.226
insulin secretionGO:0030073890.226
regulation of gliogenesisGO:0014013500.226
cellular response to sterolGO:003631520.224
positive regulation of osteoblast differentiationGO:0045669340.224
regulation of fat cell differentiationGO:0045598810.224
renal system developmentGO:00720012250.224
regulation of protein localization to nucleusGO:1900180600.223
Fly
modification dependent macromolecule catabolic processGO:00436321330.223
nucleoside metabolic processGO:00091162460.223
regulation of cellular ketone metabolic processGO:0010565660.222
prostate epithelial cord elongationGO:006052330.222
negative regulation of intracellular signal transductionGO:19025321670.222
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesisGO:200016210.221
ameboidal type cell migrationGO:00016671280.219
Fly
regulation of cardioblast differentiationGO:005189030.219
b cell activationGO:00421131610.219
purine nucleoside triphosphate catabolic processGO:00091462030.219
regulation of ras gtpase activityGO:0032318880.218
odontogenesisGO:0042476780.218
endothelium developmentGO:0003158450.215
oocyte constructionGO:000730820.214
spermatid differentiationGO:00485151150.214
prostate gland epithelium morphogenesisGO:0060740310.212
response to light stimulusGO:00094161350.211
cell growthGO:00160491300.210
sensory perception of soundGO:0007605970.210
negative regulation of t cell proliferationGO:0042130380.210
medulla oblongata developmentGO:002155030.210
lateral mesoderm morphogenesisGO:004836930.209
cell cycle checkpointGO:0000075470.209
regulation of neuron apoptotic processGO:00435231220.209
negative regulation of phosphorus metabolic processGO:00105631840.208
segmentationGO:0035282930.207
forebrain cell migrationGO:0021885580.207
embryonic digit morphogenesisGO:0042733560.206
osteoclast differentiationGO:0030316620.206
regulation of t cell proliferationGO:0042129920.205
renal system vasculature developmentGO:0061437150.204
positive regulation of cell cycle g1 s phase transitionGO:190280890.204
negative regulation of mitotic cell cycle phase transitionGO:1901991450.204
ribonucleotide metabolic processGO:00092592910.203
lung inductionGO:006049230.203
negative regulation of dendritic spine morphogenesisGO:006100230.203
positive regulation of proteolysisGO:0045862850.202
positive regulation of protein kinase activityGO:00458601440.202
oogenesisGO:0048477560.201
Worm Fly
embryonic hemopoiesisGO:0035162230.200
frontal suture morphogenesisGO:006036420.200
negative regulation of cell cycle phase transitionGO:1901988480.200
embryonic appendage morphogenesisGO:00351131260.200
regulation of transcription from rna polymerase ii promoter involved in definitive endodermal cell fate specificationGO:006080710.199

Ptch1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.958
cancerDOID:16200.957
organ system cancerDOID:005068600.957
disease of anatomical entityDOID:700.862
musculoskeletal system diseaseDOID:1700.862
connective tissue diseaseDOID:6500.862
bone diseaseDOID:008000100.238
bone development diseaseDOID:008000600.237
dysostosisDOID:193400.237
gastrointestinal system cancerDOID:311900.203