Mus musculus

440 known processes

Pten

phosphatase and tensin homolog

(Aliases: TEP1,B430203M17Rik,MMAC1,2310035O07Rik,A130070J02Rik,MGC183880,AI463227)

Pten biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regionalizationGO:00030023371.000
positive regulation of apoptotic signaling pathwayGO:2001235951.000
protein localization to organelleGO:00333651851.000
Worm
positive regulation of protein modification processGO:00314012991.000
cellular response to dna damage stimulusGO:00069742071.000
negative regulation of epithelial cell proliferationGO:0050680641.000
cell fate commitmentGO:00451652101.000
Fly
protein localization to nucleusGO:00345041211.000
Worm
regulation of cellular ketone metabolic processGO:0010565661.000
epithelial cell proliferationGO:00506731741.000
urogenital system developmentGO:00016552611.000
regulation of dna templated transcription in response to stressGO:004362091.000
regulation of cellular amine metabolic processGO:0033238201.000
regulation of sequence specific dna binding transcription factor activityGO:00510901061.000
Human
b cell differentiationGO:0030183781.000
skin developmentGO:00435882201.000
regulation of cell cycleGO:00517262811.000
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361881.000
lymphocyte differentiationGO:00300982421.000
epidermis developmentGO:00085441871.000
ovarian follicle developmentGO:0001541401.000
negative regulation of protein phosphorylationGO:00019331261.000
Human
positive regulation of apoptotic processGO:00430652171.000
mesonephric tubule developmentGO:0072164941.000
regulation of cellular amino acid metabolic processGO:000652151.000
positive regulation of macroautophagyGO:001623931.000
columnar cuboidal epithelial cell differentiationGO:0002065821.000
regulation of cellular response to stressGO:00801351591.000
Fly
negative regulation of protein metabolic processGO:00512482821.000
Human
respiratory system developmentGO:00605411901.000
Fly
spermatogenesisGO:00072832841.000
cellular senescenceGO:0090398111.000
regulation of leukocyte differentiationGO:19021051591.000
glial cell apoptotic processGO:003434931.000
regulation of myeloid leukocyte differentiationGO:0002761581.000
cellular response to radiationGO:0071478281.000
cellular response to starvationGO:0009267571.000
apoptotic signaling pathwayGO:00971903061.000
positive regulation of growthGO:00459271041.000
negative regulation of macroautophagyGO:001624251.000
respiratory tube developmentGO:00303231671.000
carbon catabolite activation of transcriptionGO:004599141.000
macroautophagyGO:0016236211.000
cellular response to gamma radiationGO:007148041.000
dna metabolic processGO:00062593031.000
protein autophosphorylationGO:0046777611.000
gland developmentGO:00487323301.000
epithelial tube morphogenesisGO:00605623031.000
embryonic organ morphogenesisGO:00485622761.000
protein import into nucleusGO:0006606951.000
Worm
negative regulation of cellular protein metabolic processGO:00322692471.000
Human
regulation of cell morphogenesis involved in differentiationGO:00107691511.000
cellular ketone metabolic processGO:0042180841.000
b cell activationGO:00421131611.000
regulation of kinase activityGO:00435492491.000
Human
erythrocyte differentiationGO:0030218881.000
regulation of mapk cascadeGO:00434082481.000
leukocyte differentiationGO:00025213421.000
negative regulation of phosphatidylinositol 3 kinase activityGO:004355311.000
positive regulation of programmed cell deathGO:00430682181.000
establishment of protein localization to organelleGO:00725941181.000
Worm
positive regulation of transcription by galactoseGO:000041111.000
kidney developmentGO:00018222131.000
positive regulation of sequence specific dna binding transcription factor activityGO:0051091681.000
Human
positive regulation of apoptotic process involved in mammary gland involutionGO:006005841.000
immune response activating signal transductionGO:00027571161.000
male gamete generationGO:00482322851.000
negative regulation of cell proliferationGO:00082852961.000
lung developmentGO:00303241641.000
positive regulation of glial cell proliferationGO:006025241.000
organ growthGO:00352651171.000
digestive tract morphogenesisGO:00485461470.999
Zebrafish
mapk cascadeGO:00001652810.999
response to starvationGO:0042594650.999
Fly
response to nutrient levelsGO:00316671090.999
Fly
regulation of canonical wnt signaling pathwayGO:0060828820.999
molting cycleGO:0042303900.999
cellular response to nutrient levelsGO:0031669640.999
response to peptideGO:19016521360.999
Fly
multicellular organism growthGO:00352641610.999
Fly
regulation of bmp signaling pathwayGO:0030510600.999
positive regulation of nervous system developmentGO:00519622210.999
regulation of protein import into nucleusGO:0042306520.999
Worm
regulation of transferase activityGO:00513382630.999
stem cell developmentGO:00488642190.999
negative regulation of transcription involved in g1 s transition of mitotic cell cycleGO:007193010.999
intrinsic apoptotic signaling pathwayGO:00971931320.999
cellular amine metabolic processGO:0044106440.999
positive regulation of neuron differentiationGO:00456661410.999
negative regulation of protein modification processGO:00314001630.999
Human
female sex differentiationGO:0046660840.999
nuclear transportGO:00511691390.999
Worm
cellular response to lipidGO:00713961450.999
response to decreased oxygen levelsGO:0036293590.999
cellular response to external stimulusGO:0071496880.999
germ cell developmentGO:00072811850.999
amine metabolic processGO:0009308450.999
carbohydrate metabolic processGO:00059752300.999
Human
prostate gland developmentGO:0030850480.999
keratinocyte differentiationGO:0030216480.999
bmp signaling pathwayGO:0030509930.999
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediatorGO:000697820.999
response to ionizing radiationGO:0010212420.999
cell agingGO:0007569350.999
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.999
negative regulation of growthGO:0045926990.999
negative regulation of phosphorus metabolic processGO:00105631840.999
Human
cellular protein catabolic processGO:00442571550.999
positive regulation of dendrite developmentGO:1900006210.999
stem cell maintenanceGO:00198271300.999
mitochondrial dna repairGO:004350430.999
negative regulation of cellular amine metabolic processGO:003323910.999
appendage morphogenesisGO:00351071490.999
appendage developmentGO:00487361660.999
cellular response to extracellular stimulusGO:0031668810.998
cytoplasmic transportGO:00164822340.998
Worm
development of primary sexual characteristicsGO:00451371430.998
regulation of neuron differentiationGO:00456642810.998
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.998
regulation of keratinocyte differentiationGO:0045616110.998
positive regulation of cell deathGO:00109422240.998
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.998
regulation of bindingGO:00510981110.998
antral ovarian follicle growthGO:000154750.998
muscle tissue developmentGO:00605373080.998
mechanoreceptor differentiationGO:0042490670.998
positive regulation of innate immune responseGO:0045089800.998
regulation of epithelial cell proliferationGO:00506781410.998
telencephalon developmentGO:00215371860.998
skeletal system developmentGO:00015013560.998
positive regulation of lymphocyte apoptotic processGO:0070230130.998
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.998
regulation of lipid kinase activityGO:0043550140.998
inner ear receptor cell differentiationGO:0060113610.998
axonogenesisGO:00074092740.998
morphogenesis of a branching structureGO:00017632030.998
leukocyte proliferationGO:00706611720.998
spermatid differentiationGO:00485151150.998
negative regulation of lipid kinase activityGO:009021910.998
cellular response to light stimulusGO:0071482190.997
regulation of protein kinase activityGO:00458592320.997
Human
extrinsic apoptotic signaling pathwayGO:00971911260.997
regulation of apoptotic signaling pathwayGO:20012331970.997
stem cell proliferationGO:00720891170.997
positive regulation of mitotic sister chromatid separationGO:190197020.997
female genitalia morphogenesisGO:004880730.997
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.997
cellular response to drugGO:0035690150.997
response to osmotic stressGO:0006970210.997
positive regulation of nitric oxide synthase activityGO:005100020.997
neural tube developmentGO:00219151600.997
regulation of lymphocyte proliferationGO:00506701170.997
cerebellum developmentGO:0021549770.997
rhythmic processGO:00485111740.997
positive regulation of kinase activityGO:00336741550.997
peptidyl amino acid modificationGO:00181933360.997
striated muscle tissue developmentGO:00147062930.997
positive regulation of cell developmentGO:00107202370.997
negative regulation of cellular amino acid metabolic processGO:004576300.997
regulation of cell adhesionGO:00301551540.997
Human
limb developmentGO:00601731660.997
gonad developmentGO:00084061410.997
positive regulation of cell proliferation involved in heart valve morphogenesisGO:000325110.997
positive regulation of release of cytochrome c from mitochondriaGO:009020050.997
activation of mapkk activityGO:0000186150.997
positive regulation of bmp signaling pathwayGO:0030513230.997
signal transduction by p53 class mediatorGO:0072331510.997
negative regulation of cell growthGO:0030308440.997
lymphocyte homeostasisGO:0002260640.997
negative regulation of photoreceptor cell differentiationGO:004653340.996
regulation of organ morphogenesisGO:20000271440.996
Fly
positive regulation of intracellular transportGO:0032388700.996
ear developmentGO:00435832000.996
Zebrafish
ovulation cycleGO:0042698590.996
defense response to other organismGO:00985421970.996
ureteric bud developmentGO:0001657940.996
lung inductionGO:006049230.996
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.996
peptidyl serine modificationGO:0018209830.996
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.996
morphogenesis of a branching epitheliumGO:00611381930.996
mammary gland epithelium developmentGO:0061180650.995
lateral inhibitionGO:004633110.995
cell cell signaling involved in cell fate commitmentGO:0045168350.995
hair cycleGO:0042633900.995
myeloid cell differentiationGO:00300992330.995
Zebrafish
regulation of cell cycle processGO:00105641600.995
negative regulation of phosphate metabolic processGO:00459361840.995
Human
regulation of macroautophagyGO:0016241120.995
chondrocyte differentiationGO:0002062720.995
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.995
regulation of myeloid cell differentiationGO:0045637960.995
embryonic appendage morphogenesisGO:00351131260.995
immature b cell differentiationGO:0002327100.995
positive regulation of mapk cascadeGO:00434101700.995
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573690.995
Human
response to peptide hormoneGO:00434341270.995
Fly
regulation of protein transportGO:00512231630.995
Worm
ossificationGO:00015032160.995
prostate glandular acinus developmentGO:0060525120.995
positive regulation of reactive oxygen species metabolic processGO:2000379110.994
homeostasis of number of cellsGO:00488722100.994
peptidyl serine phosphorylationGO:0018105740.994
branching morphogenesis of an epithelial tubeGO:00487541590.994
neuron apoptotic processGO:00514021420.994
digestive tract developmentGO:00485651900.994
Zebrafish
regulation of mitotic cell cycleGO:00073461260.994
hepaticobiliary system developmentGO:0061008670.994
negative regulation of anoikisGO:200081120.994
axon guidanceGO:00074111410.994
cellular response to acid chemicalGO:0071229680.994
synaptic transmissionGO:00072683290.993
regulation of protein localizationGO:00328802310.993
Worm
positive regulation of cholesterol transportGO:003237690.993
regulation of protein serine threonine kinase activityGO:00719001570.993
Human
negative regulation of glial cell proliferationGO:006025340.993
keratinocyte proliferationGO:0043616210.993
female gonad developmentGO:0008585710.993
liver developmentGO:0001889660.993
mitotic cell cycle arrestGO:007185040.993
regulation of lymphocyte differentiationGO:00456191070.993
photoreceptor cell differentiationGO:0046530520.993
Fly
angiogenesisGO:00015252010.993
cellular amino acid metabolic processGO:00065201030.993
t cell differentiationGO:00302171740.993
epithelial cell differentiation involved in prostate gland developmentGO:0060742130.993
sertoli cell differentiationGO:0060008180.993
regulation of cellular component sizeGO:00325351210.992
signal transduction involved in dna integrity checkpointGO:007240130.992
release of cytochrome c from mitochondriaGO:0001836230.992
response to organic cyclic compoundGO:00140701980.992
renal system developmentGO:00720012250.992
anatomical structure homeostasisGO:00602491450.992
regulation of cellular catabolic processGO:00313292420.992
regulation of reactive oxygen species metabolic processGO:2000377400.992
response to oxidative stressGO:00069791230.992
embryonic limb morphogenesisGO:00303261260.991
gastrulationGO:00073691160.991
Zebrafish
negative regulation of cell cycleGO:00457861230.991
Human
positive regulation of leukocyte apoptotic processGO:2000108210.991
regulation of map kinase activityGO:00434051200.991
positive regulation of leukocyte differentiationGO:1902107860.991
intracellular protein transportGO:00068862040.991
Worm
fatty acid metabolic processGO:00066311210.991
positive regulation of striated muscle cell apoptotic processGO:001066330.991
response to hypoxiaGO:0001666580.990
t cell activationGO:00421102890.990
regulation of protein stabilityGO:0031647520.990
Human
regulation of homeostatic processGO:00328441820.990
positive regulation of mitotic metaphase anaphase transitionGO:004584220.990
regulation of nucleocytoplasmic transportGO:0046822730.989
Worm
lymphocyte apoptotic processGO:0070227540.989
maternal placenta developmentGO:0001893200.989
fibroblast proliferationGO:0048144350.989
apoptotic process involved in mammary gland involutionGO:006005740.989
purine containing compound metabolic processGO:00725213110.988
calcium ion homeostasisGO:00550741270.988
lipid biosynthetic processGO:00086101790.988
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulusGO:190152270.988
learning or memoryGO:00076111480.987
regulation of mitotic cell cycle phase transitionGO:1901990730.987
cartilage condensationGO:0001502180.987
positive regulation of autophagyGO:001050890.987
nitrogen compound transportGO:00717052710.987
neuron projection guidanceGO:00974851410.987
regulation of anatomical structure sizeGO:00900661780.987
protein catabolic processGO:00301632210.987
epithelial cell developmentGO:00020641590.986
muscle cell differentiationGO:00426922610.986
prostate gland epithelium morphogenesisGO:0060740310.986
skeletal system morphogenesisGO:00487052030.986
regulation of intracellular transportGO:00323861590.986
Worm
cellular response to oxidative stressGO:0034599760.985
negative regulation of leukocyte proliferationGO:0070664460.985
camera type eye developmentGO:00430102660.985
proteolysis involved in cellular protein catabolic processGO:00516031470.985
reactive oxygen species metabolic processGO:0072593840.985
dna damage checkpointGO:0000077260.984
connective tissue developmentGO:00614481790.984
dendrite developmentGO:00163581150.984
negative regulation of kinase activityGO:0033673810.984
Human
photoreceptor cell morphogenesisGO:000859430.983
positive regulation of map kinase activityGO:0043406840.983
autophagyGO:0006914450.983
Fly
carbon catabolite regulation of transcriptionGO:004599040.983
regulation of muscle tissue developmentGO:1901861970.983
positive regulation of rac protein signal transductionGO:003502210.983
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.983
response to radiationGO:00093141650.983
positive regulation of transferase activityGO:00513471670.982
response to oxygen levelsGO:0070482620.982
negative regulation of mitotic cell cycleGO:0045930580.982
Human
myeloid leukocyte differentiationGO:00025731190.982
negative regulation of apoptotic signaling pathwayGO:20012341040.982
purine nucleoside metabolic processGO:00422782410.981
negative regulation of map kinase activityGO:0043407340.981
sensory organ morphogenesisGO:00905962420.981
Fly
canonical wnt signaling pathwayGO:00600701300.980
Human
positive regulation of cardiac muscle cell apoptotic processGO:001066630.980
regulation of peptidyl serine phosphorylationGO:0033135390.980
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244250.980
regulation of b cell differentiationGO:0045577230.980
cellular macromolecule catabolic processGO:00442652060.980
regulation of organelle organizationGO:00330432890.980
regulation of intracellular protein transportGO:0033157820.979
Worm
response to growth factorGO:00708481980.979
regulation of autophagyGO:0010506300.979
Fly
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.979
hindbrain developmentGO:00309021280.979
positive regulation of cellular amine metabolic processGO:003324050.979
female gamete generationGO:0007292740.979
embryonic skeletal system developmentGO:00487061200.979
positive regulation of protein serine threonine kinase activityGO:00719021060.978
negative regulation of protein serine threonine kinase activityGO:0071901490.978
Human
kidney epithelium developmentGO:00720731210.978
regulation of epidermal cell differentiationGO:0045604210.978
skeletal muscle organ developmentGO:00605381630.977
cellular response to abiotic stimulusGO:0071214560.977
positive regulation of protein kinase activityGO:00458601440.977
phagocytosisGO:0006909660.977
regulation of cell agingGO:009034290.977
dna damage response signal transduction by p53 class mediatorGO:0030330190.976
regulation of osteoblast differentiationGO:0045667670.976
mesonephric epithelium developmentGO:0072163940.976
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.976
negative regulation of t cell proliferationGO:0042130380.976
regulation of neuron apoptotic processGO:00435231220.976
protein modification by small protein conjugation or removalGO:00706472070.975
response to extracellular stimulusGO:00099911270.975
Fly
nephron tubule developmentGO:0072080840.975
purine ribonucleotide metabolic processGO:00091502900.975
peptidyl threonine phosphorylationGO:0018107310.975
regulation of transforming growth factor beta2 productionGO:003290920.975
lateral mesodermal cell differentiationGO:004837130.974
negative regulation of phosphorylationGO:00423261660.974
Human
engulfment of apoptotic cellGO:004365230.974
regulation of neuron projection developmentGO:00109751690.973
clara cell differentiationGO:006048640.973
chondrocyte developmentGO:0002063240.973
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:009729620.973
positive regulation of sterol transportGO:003237390.973
smoothened signaling pathwayGO:00072241050.973
chromatin organizationGO:00063252060.973
cellular response to x rayGO:007148120.972
endocrine system developmentGO:0035270980.972
single organism nuclear importGO:1902593950.972
Worm
embryonic heart tube morphogenesisGO:0003143510.972
chromatin modificationGO:00165681870.972
response to drugGO:0042493750.971
regulation of fibroblast proliferationGO:0048145340.971
hair follicle morphogenesisGO:0031069290.970
monocarboxylic acid metabolic processGO:00327871910.970
regulation of protein deacetylationGO:0090311170.970
lymphocyte proliferationGO:00466511640.969
regulation of fat cell differentiationGO:0045598810.969
regulation of chemotaxisGO:0050920530.969
Worm
cell growthGO:00160491300.968
purine nucleotide metabolic processGO:00061633020.968
regulation of dna replicationGO:0006275170.968
cell cycle checkpointGO:0000075470.968
regulation of osteoclast differentiationGO:0045670360.968
genitalia developmentGO:0048806370.967
negative regulation of bmp signaling pathwayGO:0030514350.967
erk1 and erk2 cascadeGO:0070371770.967
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.967
response to alcoholGO:0097305480.967
hindlimb morphogenesisGO:0035137420.967
metencephalon developmentGO:0022037890.967
negative regulation of immature t cell proliferationGO:003308730.966
regulation of mesenchymal cell proliferationGO:0010464370.966
regulation of membrane potentialGO:00423911920.965
foregut regionalizationGO:006042330.965
positive regulation of neuron apoptotic processGO:0043525250.965
protein targetingGO:00066051430.965
Worm
nucleocytoplasmic transportGO:00069131390.964
Worm
chemotaxisGO:00069352470.964
Worm
regulation of cell cycle phase transitionGO:1901987770.963
regulation of response to woundingGO:19030341890.963
Fly
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediatorGO:190225520.962
posttranscriptional regulation of gene expressionGO:00106081550.962
Human
tissue remodelingGO:00487711020.961
response to insulinGO:00328681000.961
Fly
maternal process involved in female pregnancyGO:0060135320.961
cardiac endothelial cell differentiationGO:000334840.960
neuronal action potentialGO:0019228540.960
cellular response to growth factor stimulusGO:00713631970.960
divalent inorganic cation transportGO:00725111780.960
b cell lineage commitmentGO:000232640.960
epidermis morphogenesisGO:0048730330.960
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.959
cation transportGO:00068123990.959
circulatory system processGO:00030131970.959
adaptive immune responseGO:00022501550.959
calcium ion transportGO:00068161590.958
embryonic placenta developmentGO:0001892980.957
multicellular organismal homeostasisGO:00488711640.957
intra s dna damage checkpointGO:003157340.957
positive regulation of protein phosphorylationGO:00019342420.957
canonical wnt signaling pathway involved in heart developmentGO:006131630.957
schwann cell proliferationGO:001401020.957
macromolecule catabolic processGO:00090572810.956
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.956
anterior commissure morphogenesisGO:002196060.955
regulation of feeding behaviorGO:006025930.955
cation homeostasisGO:00550802120.955
mesenchyme developmentGO:00604851520.955
divalent metal ion transportGO:00708381720.955
immune response activating cell surface receptor signaling pathwayGO:0002429720.955
stem cell differentiationGO:00488632680.955
negative regulation of leukocyte differentiationGO:1902106510.954
cardiac muscle tissue developmentGO:00487381300.953
negative regulation of protein processingGO:0010955790.952
regulation of organ growthGO:0046620610.952
positive regulation of cell migrationGO:00303351090.952
regulation of stress activated mapk cascadeGO:0032872690.952
central nervous system neuron differentiationGO:00219531620.952
determination of adult lifespanGO:0008340110.951
Worm
regulation of smad protein import into nucleusGO:006039030.950
retina development in camera type eyeGO:00600411190.949
osteoblast developmentGO:0002076170.949
purine containing compound biosynthetic processGO:0072522700.949
neuron deathGO:00709971540.949
positive regulation of cellular amino acid metabolic processGO:004576430.948
regulation of cell projection organizationGO:00313442060.948
cell type specific apoptotic processGO:00972852680.947
immune response regulating signaling pathwayGO:00027641250.947
stress activated protein kinase signaling cascadeGO:0031098810.947
carbon catabolite activation of transcription from rna polymerase ii promoterGO:000043640.947
hair follicle developmentGO:0001942850.947
cellular calcium ion homeostasisGO:00068741190.946
positive regulation of stem cell proliferationGO:2000648590.946
regulation of cell migration involved in sprouting angiogenesisGO:009004940.945
regulation of chromatin modificationGO:1903308570.945
regulation of transcription by galactoseGO:000040910.944
thymocyte apoptotic processGO:0070242190.944
cellular response to retinoic acidGO:0071300250.944
ribonucleotide metabolic processGO:00092592910.943
canonical wnt signaling pathway involved in regulation of cell proliferationGO:004434030.943
response to amino acidGO:0043200370.942
regulation of ion transportGO:00432692150.942
regulation of cytoplasmic transportGO:19036491120.942
Worm
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.942
negative regulation of neuron deathGO:1901215980.941
mammary gland branching involved in pregnancyGO:006074560.941
lateral mesoderm morphogenesisGO:004836930.941
neural tube closureGO:0001843900.940
embryonic hemopoiesisGO:0035162230.940
negative regulation of neuron apoptotic processGO:0043524920.939
epithelial cell proliferation involved in prostate gland developmentGO:0060767110.939
cholesterol homeostasisGO:0042632440.939
metal ion homeostasisGO:00550651890.939
peptidyl threonine modificationGO:0018210310.938
morphogenesis of embryonic epitheliumGO:00163311590.938
intracellular steroid hormone receptor signaling pathwayGO:0030518290.938
activation of adenylate cyclase activityGO:000719040.938
intracellular signal transduction involved in g1 dna damage checkpointGO:190240030.938
cerebellum morphogenesisGO:0021587420.937
proteasomal protein catabolic processGO:0010498980.936
alpha beta t cell differentiationGO:0046632690.936
stress induced premature senescenceGO:009040020.935
negative regulation of immune system processGO:00026832090.935
forebrain developmentGO:00309003020.934
programmed necrotic cell deathGO:0097300280.932
regulation of purine nucleotide biosynthetic processGO:1900371340.932
positive regulation of glial cell differentiationGO:0045687210.932
small molecule biosynthetic processGO:00442831320.931
organic hydroxy compound metabolic processGO:19016152030.931
Human Fly
negative regulation of jun kinase activityGO:004350890.930
cognitionGO:00508901490.929
positive regulation of b cell proliferationGO:0030890240.929
regulation of epithelial cell migrationGO:0010632350.929
type i pneumocyte differentiationGO:006050970.928
negative regulation of organ growthGO:0046621170.927
neuroblast proliferationGO:0007405490.927
divalent inorganic cation homeostasisGO:00725071380.927
regulation of protein targetingGO:1903533610.926
Worm
regulation of t cell differentiationGO:0045580830.926
ensheathment of neuronsGO:0007272760.926
immune response regulating cell surface receptor signaling pathwayGO:0002768800.926
positive regulation of osteoblast differentiationGO:0045669340.925
regulation of cellular senescenceGO:200077260.925

Pten disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456601.000
Human
thoracic cancerDOID:509300.999
cancerDOID:16200.999
Human
organ system cancerDOID:005068600.999
Human
large intestine cancerDOID:567200.998
colon cancerDOID:21900.998
gastrointestinal system cancerDOID:311900.998
intestinal cancerDOID:1015500.998
colorectal cancerDOID:925600.998
liver carcinomaDOID:68600.994
liver cancerDOID:357100.994
endocrine gland cancerDOID:17000.992
Human
pancreatic cancerDOID:179300.989
breast cancerDOID:161200.985
respiratory system cancerDOID:005061500.985
hepatocellular carcinomaDOID:68400.943