IMP: Integrative Multi-species Prediction

Mus musculus

27 known processes

Ptk6

PTK6 protein tyrosine kinase 6

(Aliases: Sik,BRK,Tksk,tks)

Entrez: 20459
Ensembl: ENSMUSG00000038751
UniProtKB: Q64434
UniProtKB: Q05AA8

Process Predictions
Disease Predictions

Ptk6 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cellular ketone metabolic process	GO:0042180	84	0.660
transforming growth factor beta secretion	GO:0038044	1	0.529
regulation of transforming growth factor beta secretion	GO:2001201	1	0.465
regulation of body fluid levels	GO:0050878	162	0.463	Mouse
cellular lipid metabolic process	GO:0044255	323	0.419	Mouse
positive regulation of transforming growth factor beta secretion	GO:2001203	1	0.414
monocarboxylic acid metabolic process	GO:0032787	191	0.330
lipid biosynthetic process	GO:0008610	179	0.328
coagulation	GO:0050817	78	0.320	Mouse
defense response to other organism	GO:0098542	197	0.312	Mouse
regulation of defense response	GO:0031347	233	0.250	Mouse
cytokine production	GO:0001816	319	0.236	Mouse
response to acid chemical	GO:0001101	111	0.216	Human Mouse
nucleotide metabolic process	GO:0009117	332	0.207
oxidation reduction process	GO:0055114	342	0.204
regulation of protein localization	GO:0032880	231	0.196	Mouse
fatty acid metabolic process	GO:0006631	121	0.193
positive regulation of cytokine production	GO:0001819	174	0.184	Mouse
regulation of cellular ketone metabolic process	GO:0010565	66	0.176
muscle tissue development	GO:0060537	308	0.168
angiogenesis	GO:0001525	201	0.162
purine ribonucleotide metabolic process	GO:0009150	290	0.160
amine metabolic process	GO:0009308	45	0.159
inflammatory response	GO:0006954	244	0.148	Mouse
nucleobase containing small molecule metabolic process	GO:0055086	352	0.146
peptidyl amino acid modification	GO:0018193	336	0.141	Human Mouse
apoptotic signaling pathway	GO:0097190	306	0.140
positive regulation of cellular amine metabolic process	GO:0033240	5	0.139
epidermis development	GO:0008544	187	0.137
carbohydrate transport	GO:0008643	62	0.136	Mouse
organic hydroxy compound metabolic process	GO:1901615	203	0.136
regulation of cytokine production	GO:0001817	266	0.133	Mouse
regulation of protein secretion	GO:0050708	82	0.133	Mouse
cellular amino acid metabolic process	GO:0006520	103	0.132
carbohydrate derivative biosynthetic process	GO:1901137	183	0.128
appendage morphogenesis	GO:0035107	149	0.127
regulation of cellular amino acid metabolic process	GO:0006521	5	0.124
anatomical structure homeostasis	GO:0060249	145	0.121	Mouse
sensory perception	GO:0007600	245	0.119	Mouse
regulation of hydrolase activity	GO:0051336	246	0.116	Mouse
ribose phosphate metabolic process	GO:0019693	291	0.115
regulation of nucleotide metabolic process	GO:0006140	169	0.113
steroid metabolic process	GO:0008202	119	0.113
purine nucleotide metabolic process	GO:0006163	302	0.110
organonitrogen compound catabolic process	GO:1901565	264	0.110
regulation of protein transport	GO:0051223	163	0.109	Mouse
regulation of interleukin 10 secretion	GO:2001179	4	0.108
ameboidal type cell migration	GO:0001667	128	0.108
cardiac muscle tissue development	GO:0048738	130	0.107
defense response to bacterium	GO:0042742	119	0.105	Mouse
organophosphate biosynthetic process	GO:0090407	122	0.105
epithelial cell proliferation	GO:0050673	174	0.102
nucleoside phosphate metabolic process	GO:0006753	338	0.101
positive regulation of cell development	GO:0010720	237	0.101	Human Mouse
positive regulation of cell migration	GO:0030335	109	0.100	Mouse
cellular amine metabolic process	GO:0044106	44	0.098
alcohol metabolic process	GO:0006066	116	0.097
leukocyte differentiation	GO:0002521	342	0.097	Mouse
regulation of cell cycle	GO:0051726	281	0.096
regulation of purine nucleotide metabolic process	GO:1900542	169	0.095
regulation of cellular amine metabolic process	GO:0033238	20	0.094
drug catabolic process	GO:0042737	2	0.093
blood vessel morphogenesis	GO:0048514	285	0.093
forebrain development	GO:0030900	302	0.093	Mouse
interleukin 10 secretion	GO:0072608	4	0.092
purine containing compound metabolic process	GO:0072521	311	0.090
peptidyl serine modification	GO:0018209	83	0.090
regulation of lymphocyte activation	GO:0051249	240	0.087	Mouse
regulation of vasculature development	GO:1901342	88	0.087
appendage development	GO:0048736	166	0.086
negative regulation of cell proliferation	GO:0008285	296	0.085	Mouse
extrinsic apoptotic signaling pathway	GO:0097191	126	0.085
immune effector process	GO:0002252	321	0.084	Mouse
ribonucleotide metabolic process	GO:0009259	291	0.084
adaptive immune response	GO:0002250	155	0.083	Mouse
extracellular structure organization	GO:0043062	148	0.083
exogenous drug catabolic process	GO:0042738	1	0.083
regulation of epithelial cell proliferation	GO:0050678	141	0.081
epithelial tube morphogenesis	GO:0060562	303	0.080	Mouse
regulation of muscle tissue development	GO:1901861	97	0.078
positive regulation of neuron differentiation	GO:0045666	141	0.078	Human Mouse
carbohydrate metabolic process	GO:0005975	230	0.077
regulation of cellular component size	GO:0032535	121	0.077
spermatogenesis	GO:0007283	284	0.077
regulation of cell migration	GO:0030334	219	0.077	Mouse
response to lipopolysaccharide	GO:0032496	128	0.077	Mouse
male gamete generation	GO:0048232	285	0.076
organic hydroxy compound biosynthetic process	GO:1901617	77	0.074
tissue remodeling	GO:0048771	102	0.074	Mouse
limb development	GO:0060173	166	0.074
response to inorganic substance	GO:0010035	96	0.073
positive regulation of defense response	GO:0031349	124	0.072	Mouse
hair follicle development	GO:0001942	85	0.072
skin development	GO:0043588	220	0.071
regulation of mapk cascade	GO:0043408	248	0.071	Mouse
regulation of neuron projection development	GO:0010975	169	0.071	Human Mouse
regulation of secretion by cell	GO:1903530	249	0.070	Mouse
morphogenesis of a branching epithelium	GO:0061138	193	0.069	Mouse
small molecule biosynthetic process	GO:0044283	132	0.068
glycerolipid metabolic process	GO:0046486	122	0.067	Mouse
blood coagulation	GO:0007596	76	0.067	Mouse
regulation of neuron differentiation	GO:0045664	281	0.067	Human Mouse
cation homeostasis	GO:0055080	212	0.067	Mouse
positive regulation of mapk cascade	GO:0043410	170	0.066	Mouse
cellular homeostasis	GO:0019725	240	0.066	Mouse
developmental maturation	GO:0021700	193	0.065	Mouse
organic cyclic compound catabolic process	GO:1901361	295	0.065
regulation of wound healing	GO:0061041	40	0.063	Mouse
cellular alcohol biosynthetic process	GO:0044108	3	0.063
regulation of anatomical structure size	GO:0090066	178	0.062
defense response to gram positive bacterium	GO:0050830	50	0.061	Mouse
cell recognition	GO:0008037	83	0.061
embryonic placenta development	GO:0001892	98	0.060
g protein coupled receptor signaling pathway	GO:0007186	243	0.060
cellular ion homeostasis	GO:0006873	165	0.059	Mouse
multicellular organismal homeostasis	GO:0048871	164	0.059	Mouse
hemostasis	GO:0007599	78	0.059	Mouse
innate immune response activating signal transduction	GO:0002758	50	0.059	Mouse
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.059
regulation of innate immune response	GO:0045088	91	0.058	Mouse
limb morphogenesis	GO:0035108	149	0.058
regulation of protein catabolic process	GO:0042176	108	0.058	Mouse
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	54	0.056
organic anion transport	GO:0015711	137	0.056
molting cycle	GO:0042303	90	0.055
immune response activating cell surface receptor signaling pathway	GO:0002429	72	0.055	Mouse
cellular response to hormone stimulus	GO:0032870	150	0.054
hair follicle morphogenesis	GO:0031069	29	0.053
organ growth	GO:0035265	117	0.053
striated muscle tissue development	GO:0014706	293	0.052
cell activation involved in immune response	GO:0002263	126	0.052	Mouse
organonitrogen compound biosynthetic process	GO:1901566	192	0.052
gland development	GO:0048732	330	0.052	Mouse
muscle cell differentiation	GO:0042692	261	0.052
cell growth	GO:0016049	130	0.051
regulation of lipid metabolic process	GO:0019216	118	0.050	Mouse
wound healing	GO:0042060	157	0.050	Mouse
drug metabolic process	GO:0017144	4	0.050
columnar cuboidal epithelial cell differentiation	GO:0002065	82	0.049
detection of stimulus	GO:0051606	84	0.049	Mouse
regulation of secretion	GO:0051046	274	0.048	Mouse
hexose metabolic process	GO:0019318	98	0.047
myeloid cell differentiation	GO:0030099	233	0.047	Mouse
positive regulation of apoptotic process	GO:0043065	217	0.047	Mouse
leukocyte activation involved in immune response	GO:0002366	126	0.047	Mouse
cell type specific apoptotic process	GO:0097285	268	0.047	Mouse
regulation of cell projection organization	GO:0031344	206	0.047	Human Mouse
regulation of blood coagulation	GO:0030193	28	0.047	Mouse
negative regulation of protein metabolic process	GO:0051248	282	0.046	Human Mouse
glycosyl compound catabolic process	GO:1901658	206	0.046
cytokine mediated signaling pathway	GO:0019221	115	0.046
immune response activating signal transduction	GO:0002757	116	0.045	Mouse
purine nucleotide biosynthetic process	GO:0006164	65	0.045
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.045
protein catabolic process	GO:0030163	221	0.045	Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.045
response to molecule of bacterial origin	GO:0002237	143	0.045	Mouse
cellular nitrogen compound catabolic process	GO:0044270	280	0.044
regulation of cell cycle process	GO:0010564	160	0.044
regulation of coagulation	GO:0050818	31	0.044	Mouse
hair cycle	GO:0042633	90	0.043
tube formation	GO:0035148	140	0.043
response to growth factor	GO:0070848	198	0.043	Mouse
negative regulation of homeostatic process	GO:0032845	71	0.042	Mouse
cellular response to molecule of bacterial origin	GO:0071219	83	0.042	Mouse
muscle cell development	GO:0055001	133	0.042
positive regulation of homeostatic process	GO:0032846	64	0.042
negative regulation of lipid metabolic process	GO:0045833	30	0.042
organophosphate catabolic process	GO:0046434	232	0.041
monosaccharide transport	GO:0015749	58	0.041	Mouse
positive regulation of cell motility	GO:2000147	116	0.041	Mouse
meiotic cell cycle	GO:0051321	122	0.040
hematopoietic progenitor cell differentiation	GO:0002244	143	0.040
positive regulation of innate immune response	GO:0045089	80	0.040	Mouse
cell cell junction organization	GO:0045216	72	0.040
negative regulation of growth	GO:0045926	99	0.040
morphogenesis of a branching structure	GO:0001763	203	0.040	Mouse
regulation of cell activation	GO:0050865	289	0.040	Mouse
regulation of cellular component biogenesis	GO:0044087	181	0.040	Mouse
endomembrane system organization	GO:0010256	147	0.040
striated muscle cell development	GO:0055002	125	0.040
ribonucleoside catabolic process	GO:0042454	206	0.040
monocarboxylic acid biosynthetic process	GO:0072330	61	0.039
purine ribonucleotide catabolic process	GO:0009154	208	0.039
purine nucleoside metabolic process	GO:0042278	241	0.038
myotube differentiation	GO:0014902	105	0.038
protein maturation	GO:0051604	176	0.038
ribonucleoside metabolic process	GO:0009119	245	0.038
regulation of lipid biosynthetic process	GO:0046890	54	0.038
extracellular matrix organization	GO:0030198	147	0.038
anion transmembrane transport	GO:0098656	71	0.038
regulation of proteolysis	GO:0030162	164	0.038
regulation of organelle organization	GO:0033043	289	0.038	Mouse
alcohol biosynthetic process	GO:0046165	43	0.038
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.037
actin filament organization	GO:0007015	113	0.037
ras protein signal transduction	GO:0007265	77	0.037
regulation of hormone levels	GO:0010817	211	0.037
cyclic nucleotide biosynthetic process	GO:0009190	44	0.037
ribonucleotide biosynthetic process	GO:0009260	59	0.037
immune response regulating signaling pathway	GO:0002764	125	0.037	Mouse
aromatic compound catabolic process	GO:0019439	286	0.037
cytokine secretion	GO:0050663	72	0.037	Mouse
positive regulation of protein phosphorylation	GO:0001934	242	0.037	Mouse
response to organonitrogen compound	GO:0010243	246	0.036
cation transport	GO:0006812	399	0.036	Mouse
reactive nitrogen species metabolic process	GO:2001057	0	0.036
glucose transport	GO:0015758	56	0.036	Mouse
mitotic cell cycle	GO:0000278	195	0.036
isoprenoid metabolic process	GO:0006720	29	0.036
anion transport	GO:0006820	177	0.036
negative regulation of cell activation	GO:0050866	111	0.036	Mouse
response to steroid hormone	GO:0048545	56	0.036
regulation of lymphocyte proliferation	GO:0050670	117	0.036	Mouse
keratinocyte proliferation	GO:0043616	21	0.035
small gtpase mediated signal transduction	GO:0007264	97	0.035
positive regulation of programmed cell death	GO:0043068	218	0.035	Mouse
nuclear division	GO:0000280	158	0.035
mapk cascade	GO:0000165	281	0.035	Mouse
inorganic ion transmembrane transport	GO:0098660	234	0.035
glial cell apoptotic process	GO:0034349	3	0.035
neural tube formation	GO:0001841	108	0.035
regulation of cell size	GO:0008361	72	0.035
embryonic epithelial tube formation	GO:0001838	130	0.034
cellular response to organonitrogen compound	GO:0071417	145	0.034
regulation of cell motility	GO:2000145	236	0.034	Mouse
negative regulation of epithelial cell proliferation	GO:0050680	64	0.034
negative regulation of phosphate metabolic process	GO:0045936	184	0.034	Human Mouse
mesenchyme development	GO:0060485	152	0.034
purine ribonucleoside metabolic process	GO:0046128	241	0.034
rho protein signal transduction	GO:0007266	32	0.034
positive regulation of purine nucleotide metabolic process	GO:1900544	114	0.034
cofactor metabolic process	GO:0051186	80	0.034
digestive tract morphogenesis	GO:0048546	147	0.033
neural tube development	GO:0021915	160	0.033
morphogenesis of embryonic epithelium	GO:0016331	159	0.033
nucleoside triphosphate catabolic process	GO:0009143	205	0.033
regulation of response to wounding	GO:1903034	189	0.033	Mouse
nucleoside phosphate catabolic process	GO:1901292	222	0.033
regulation of cytoskeleton organization	GO:0051493	122	0.033
regulation of angiogenesis	GO:0045765	81	0.033
negative regulation of protein modification process	GO:0031400	163	0.033	Human Mouse
cellular response to acid chemical	GO:0071229	68	0.033	Human Mouse
regulation of steroid biosynthetic process	GO:0050810	26	0.033
myeloid leukocyte migration	GO:0097529	57	0.032
negative regulation of cellular protein metabolic process	GO:0032269	247	0.032	Human Mouse
chemotaxis	GO:0006935	247	0.032
terpenoid metabolic process	GO:0006721	25	0.032
nitrogen compound transport	GO:0071705	271	0.032
membrane organization	GO:0061024	245	0.031
maintenance of location	GO:0051235	89	0.031	Mouse
stem cell development	GO:0048864	219	0.031
stem cell differentiation	GO:0048863	268	0.031
leukocyte chemotaxis	GO:0030595	69	0.031
intermediate filament organization	GO:0045109	15	0.031
regulation of system process	GO:0044057	200	0.031
protein glycosylation	GO:0006486	55	0.031
purine containing compound catabolic process	GO:0072523	213	0.031
reactive oxygen species metabolic process	GO:0072593	84	0.031
macromolecule glycosylation	GO:0043413	55	0.031
placenta development	GO:0001890	140	0.030
epithelial tube formation	GO:0072175	130	0.030
epithelial cell migration	GO:0010631	63	0.030
regulation of homeostatic process	GO:0032844	182	0.030	Mouse
biomineral tissue development	GO:0031214	64	0.030
regulation of leukocyte proliferation	GO:0070663	121	0.030	Mouse
negative regulation of cellular component organization	GO:0051129	194	0.030
cell division	GO:0051301	120	0.030
divalent inorganic cation homeostasis	GO:0072507	138	0.030	Mouse
embryonic limb morphogenesis	GO:0030326	126	0.030
activation of immune response	GO:0002253	138	0.030	Mouse
ribose phosphate biosynthetic process	GO:0046390	59	0.030
organic acid biosynthetic process	GO:0016053	86	0.030
regulation of actin cytoskeleton organization	GO:0032956	84	0.030
steroid biosynthetic process	GO:0006694	47	0.029
glycoprotein metabolic process	GO:0009100	116	0.029
cell adhesion	GO:0007155	329	0.029	Mouse
regulation of establishment of protein localization	GO:0070201	181	0.029	Mouse
positive regulation of angiogenesis	GO:0045766	46	0.029
regulation of t cell activation	GO:0050863	170	0.029	Mouse
regulation of cell adhesion	GO:0030155	154	0.029	Mouse
myeloid leukocyte differentiation	GO:0002573	119	0.029	Mouse
posttranscriptional regulation of gene expression	GO:0010608	155	0.029
primary neural tube formation	GO:0014020	95	0.029
regulation of transferase activity	GO:0051338	263	0.029	Human Mouse
glucose metabolic process	GO:0006006	92	0.029
protein processing	GO:0016485	163	0.029
nucleotide biosynthetic process	GO:0009165	78	0.029
organic acid transport	GO:0015849	101	0.029
response to amino acid	GO:0043200	37	0.028
nucleoside phosphate biosynthetic process	GO:1901293	79	0.028
lymphocyte differentiation	GO:0030098	242	0.028	Mouse
leukocyte mediated immunity	GO:0002443	174	0.028	Mouse
germ cell development	GO:0007281	185	0.028	Mouse
canonical wnt signaling pathway	GO:0060070	130	0.028	Mouse
macromolecule catabolic process	GO:0009057	281	0.028	Mouse
b cell activation	GO:0042113	161	0.028	Mouse
response to oxidative stress	GO:0006979	123	0.028
purine containing compound biosynthetic process	GO:0072522	70	0.028
cellular response to transforming growth factor beta stimulus	GO:0071560	88	0.028	Mouse
negative regulation of cell morphogenesis involved in differentiation	GO:0010771	48	0.028
actin cytoskeleton organization	GO:0030036	220	0.028
nucleoside triphosphate metabolic process	GO:0009141	230	0.028
glycosyl compound metabolic process	GO:1901657	246	0.028
cellular response to biotic stimulus	GO:0071216	92	0.028	Mouse
regulation of purine nucleotide catabolic process	GO:0033121	122	0.027
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	61	0.027	Mouse
response to transforming growth factor beta	GO:0071559	88	0.027	Mouse
response to peptide hormone	GO:0043434	127	0.027
regulation of protein complex assembly	GO:0043254	83	0.027	Mouse
regulation of cytokine secretion	GO:0050707	61	0.027	Mouse
formation of primary germ layer	GO:0001704	77	0.027
glucose homeostasis	GO:0042593	128	0.027
monosaccharide metabolic process	GO:0005996	106	0.027
blood circulation	GO:0008015	195	0.026
osteoclast differentiation	GO:0030316	62	0.026	Mouse
branching morphogenesis of an epithelial tube	GO:0048754	159	0.026	Mouse
central nervous system morphogenesis	GO:0021551	2	0.026
negative regulation of synapse assembly	GO:0051964	3	0.026
negative regulation of lymphocyte activation	GO:0051250	91	0.026	Mouse
negative regulation of nervous system development	GO:0051961	156	0.026
positive regulation of neuron projection development	GO:0010976	79	0.026	Human Mouse
positive regulation of growth	GO:0045927	104	0.026
cell differentiation involved in embryonic placenta development	GO:0060706	26	0.026
digestive tract development	GO:0048565	190	0.026
reactive oxygen species biosynthetic process	GO:1903409	8	0.026
cardiocyte differentiation	GO:0035051	87	0.026
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	88	0.025
myoblast differentiation	GO:0045445	52	0.025
regulation of cell growth	GO:0001558	91	0.025
regulation of inflammatory response	GO:0050727	147	0.025	Mouse
pattern recognition receptor signaling pathway	GO:0002221	47	0.025	Mouse
leukocyte mediated cytotoxicity	GO:0001909	62	0.025
regulation of reactive oxygen species biosynthetic process	GO:1903426	2	0.025
positive regulation of phospholipase c activity	GO:0010863	2	0.025	Mouse
circulatory system process	GO:0003013	197	0.025
carbohydrate derivative catabolic process	GO:1901136	231	0.025
positive regulation of cytosolic calcium ion concentration	GO:0007204	65	0.025	Mouse
single organismal cell cell adhesion	GO:0016337	131	0.025	Mouse
regulation of steroid metabolic process	GO:0019218	39	0.024
epithelial cell morphogenesis	GO:0003382	41	0.024
kidney development	GO:0001822	213	0.024
protein localization to plasma membrane	GO:0072659	57	0.024
erk1 and erk2 cascade	GO:0070371	77	0.024	Mouse
tissue homeostasis	GO:0001894	115	0.024	Mouse
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.024
purine ribonucleotide biosynthetic process	GO:0009152	59	0.024
positive regulation of cell adhesion	GO:0045785	80	0.024
lymphocyte apoptotic process	GO:0070227	54	0.024	Mouse
antibacterial peptide production	GO:0002778	2	0.024
negative regulation of immune system process	GO:0002683	209	0.024	Mouse
positive regulation of reactive oxygen species metabolic process	GO:2000379	11	0.024
peptidyl tyrosine phosphorylation	GO:0018108	143	0.024	Human Mouse
keratinocyte migration	GO:0051546	3	0.024
positive regulation of nucleotide metabolic process	GO:0045981	114	0.023
regulation of keratinocyte differentiation	GO:0045616	11	0.023
regulation of apoptotic signaling pathway	GO:2001233	197	0.023
homeostasis of number of cells	GO:0048872	210	0.023	Mouse
granulocyte migration	GO:0097530	43	0.023
nucleocytoplasmic transport	GO:0006913	139	0.023
myeloid leukocyte mediated immunity	GO:0002444	42	0.023	Mouse
carbohydrate biosynthetic process	GO:0016051	74	0.023
positive regulation of organelle organization	GO:0010638	128	0.023	Mouse
positive regulation of wnt signaling pathway	GO:0030177	45	0.023	Mouse
skin morphogenesis	GO:0043589	38	0.023
hindbrain development	GO:0030902	128	0.023
carboxylic acid transport	GO:0046942	100	0.023
transmission of nerve impulse	GO:0019226	76	0.023
regulation of organ morphogenesis	GO:2000027	144	0.023
regulation of mitotic cell cycle	GO:0007346	126	0.023
wnt signaling pathway	GO:0016055	188	0.023	Mouse
regulation of wnt signaling pathway	GO:0030111	123	0.023	Mouse
tissue migration	GO:0090130	68	0.023
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.023
cellular response to amino acid stimulus	GO:0071230	29	0.022
hormone metabolic process	GO:0042445	86	0.022
regulation of ossification	GO:0030278	112	0.022
positive regulation of protein modification process	GO:0031401	299	0.022	Mouse
cyclic nucleotide metabolic process	GO:0009187	59	0.022
metal ion homeostasis	GO:0055065	189	0.022	Mouse
cellular alcohol metabolic process	GO:0044107	3	0.022
positive regulation of nervous system development	GO:0051962	221	0.022	Human Mouse
compound eye development	GO:0048749	1	0.022
regulation of chemotaxis	GO:0050920	53	0.022
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	247	0.022
glycosylation	GO:0070085	62	0.022
stem cell proliferation	GO:0072089	117	0.022
fat soluble vitamin biosynthetic process	GO:0042362	4	0.022
positive regulation of reactive oxygen species biosynthetic process	GO:1903428	2	0.022
regulation of nucleotide catabolic process	GO:0030811	122	0.022
epithelial cell development	GO:0002064	159	0.022
negative regulation of cell motility	GO:2000146	61	0.022
exocrine system development	GO:0035272	45	0.022
bone mineralization	GO:0030282	54	0.022
ribonucleotide catabolic process	GO:0009261	208	0.022
camera type eye development	GO:0043010	266	0.022
muscle fiber development	GO:0048747	76	0.022
regulation of endocytosis	GO:0030100	69	0.022	Mouse
production of molecular mediator of immune response	GO:0002440	103	0.021
negative regulation of endothelial cell migration	GO:0010596	4	0.021
lipid localization	GO:0010876	126	0.021
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.021
negative regulation of cell migration	GO:0030336	59	0.021
purine ribonucleoside catabolic process	GO:0046130	205	0.021
peptidyl tyrosine modification	GO:0018212	145	0.021	Human Mouse
regulation of nuclear division	GO:0051783	56	0.021
intestinal epithelial structure maintenance	GO:0060729	4	0.021
ossification	GO:0001503	216	0.021
branching involved in salivary gland morphogenesis	GO:0060445	26	0.021
mesenchymal cell development	GO:0014031	93	0.021
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.021
regulation of fat cell differentiation	GO:0045598	81	0.021
regulation of vesicle mediated transport	GO:0060627	139	0.021	Mouse
second messenger mediated signaling	GO:0019932	73	0.021
cellular metal ion homeostasis	GO:0006875	151	0.021	Mouse
regulation of protein serine threonine kinase activity	GO:0071900	157	0.020	Mouse
developmental growth involved in morphogenesis	GO:0060560	138	0.020
mast cell proliferation	GO:0070662	4	0.020	Mouse
insulin receptor signaling pathway	GO:0008286	49	0.020
positive regulation of cellular catabolic process	GO:0031331	148	0.020
nucleoside catabolic process	GO:0009164	206	0.020
secondary metabolic process	GO:0019748	18	0.020
mesenchyme morphogenesis	GO:0072132	32	0.020
mesenchymal cell differentiation	GO:0048762	107	0.020
neutrophil mediated killing of gram positive bacterium	GO:0070946	2	0.020
skeletal system morphogenesis	GO:0048705	203	0.020
negative regulation of response to wounding	GO:1903035	77	0.020
regulation of canonical wnt signaling pathway	GO:0060828	82	0.020	Mouse
transmembrane transport	GO:0055085	412	0.020
single organism cell adhesion	GO:0098602	156	0.020	Mouse
negative regulation of b cell activation	GO:0050869	27	0.020	Mouse
mitochondrion organization	GO:0007005	134	0.020
dna metabolic process	GO:0006259	303	0.020
regulation of hemostasis	GO:1900046	28	0.020	Mouse
peptide hormone secretion	GO:0030072	109	0.020
carboxylic acid biosynthetic process	GO:0046394	86	0.020
organelle fission	GO:0048285	170	0.020
cell junction assembly	GO:0034329	52	0.020
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.020
dendrite development	GO:0016358	115	0.020	Mouse
hexose transport	GO:0008645	56	0.020	Mouse
fat cell differentiation	GO:0045444	160	0.019
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.019
skeletal muscle organ development	GO:0060538	163	0.019
regulation of metal ion transport	GO:0010959	106	0.019	Mouse
purine nucleoside catabolic process	GO:0006152	205	0.019
cellular calcium ion homeostasis	GO:0006874	119	0.019	Mouse
response to extracellular stimulus	GO:0009991	127	0.019
regulation of cellular catabolic process	GO:0031329	242	0.019
negative regulation of leukocyte proliferation	GO:0070664	46	0.019	Mouse
keratinocyte differentiation	GO:0030216	48	0.019
regulation of endopeptidase activity	GO:0052548	89	0.019
jak stat cascade	GO:0007259	42	0.019	Human Mouse
leukocyte apoptotic process	GO:0071887	71	0.019	Mouse
determination of left right symmetry	GO:0007368	80	0.019
retinoic acid metabolic process	GO:0042573	12	0.019
thermosensory behavior	GO:0040040	1	0.019
engulfment of apoptotic cell	GO:0043652	3	0.019
epithelium migration	GO:0090132	63	0.019
mesonephros development	GO:0001823	97	0.019
connective tissue development	GO:0061448	179	0.018
mitotic cell cycle process	GO:1903047	159	0.018
calcitriol biosynthetic process from calciol	GO:0036378	3	0.018
positive regulation of epithelial cell proliferation	GO:0050679	68	0.018
regulation of extrinsic apoptotic signaling pathway	GO:2001236	77	0.018
nucleotide catabolic process	GO:0009166	217	0.018
action potential	GO:0001508	78	0.018
sulfur compound metabolic process	GO:0006790	100	0.018
cellular macromolecule catabolic process	GO:0044265	206	0.018
nucleoside metabolic process	GO:0009116	246	0.018
heterocycle catabolic process	GO:0046700	280	0.018
guanosine containing compound metabolic process	GO:1901068	144	0.018
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.018
multicellular organismal signaling	GO:0035637	91	0.018
respiratory system development	GO:0060541	190	0.018
regulation of ras protein signal transduction	GO:0046578	114	0.018
neuromuscular process	GO:0050905	99	0.018
skeletal system development	GO:0001501	356	0.018
carbohydrate homeostasis	GO:0033500	128	0.018
regulation of myotube differentiation	GO:0010830	62	0.018
positive regulation of cytokine secretion	GO:0050715	41	0.018	Mouse
leukocyte homeostasis	GO:0001776	79	0.018	Mouse
regulation of cytoplasmic transport	GO:1903649	112	0.018	Mouse
positive regulation of immune effector process	GO:0002699	107	0.018	Mouse
mitral valve morphogenesis	GO:0003183	4	0.018
positive regulation of hydrolase activity	GO:0051345	148	0.018	Mouse
neuron migration	GO:0001764	122	0.018	Mouse
cell killing	GO:0001906	67	0.018
regulation of epidermal cell differentiation	GO:0045604	21	0.018
regeneration	GO:0031099	38	0.018
regulation of peptidase activity	GO:0052547	96	0.017
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.017	Mouse

Ptk6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.057
inherited metabolic disorder	DOID:655	0.057
musculoskeletal system disease	DOID:17	0.030
disease of anatomical entity	DOID:7	0.030
connective tissue disease	DOID:65	0.028
bone disease	DOID:0080001	0.028
cardiovascular system disease	DOID:1287	0.020

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