Mus musculus

77 known processes

Ptpn22

protein tyrosine phosphatase, non-receptor type 22 (lymphoid)

(Aliases: Ptpn8,PEP,70zpep)

Ptpn22 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cation transportGO:00068123990.764
amine metabolic processGO:0009308450.760
positive regulation of cellular amine metabolic processGO:003324050.746
t cell proliferationGO:00420981200.723
release of cytochrome c from mitochondriaGO:0001836230.722
defense response to other organismGO:00985421970.718
immune response activating signal transductionGO:00027571160.704
immune effector processGO:00022523210.698
dephosphorylationGO:00163111290.661
cell activation involved in immune responseGO:00022631260.623
regulation of homotypic cell cell adhesionGO:0034110130.603
regulation of alpha beta t cell differentiationGO:0046637350.596
regulation of lymphocyte activationGO:00512492400.594
immune response regulating signaling pathwayGO:00027641250.594
leukocyte mediated immunityGO:00024431740.592
t cell differentiationGO:00302171740.589
positive regulation of gamma delta t cell differentiationGO:004558860.580
single organism cell adhesionGO:00986021560.573
myeloid leukocyte activationGO:0002274830.551
positive regulation of alpha beta t cell differentiationGO:0046638280.548
t helper 2 cell cytokine productionGO:003574540.533
cellular nitrogen compound catabolic processGO:00442702800.526
interleukin 2 productionGO:0032623330.521
negative regulation of cellular amine metabolic processGO:003323910.517
ras protein signal transductionGO:0007265770.513
positive regulation of cellular amino acid metabolic processGO:004576430.512
positive regulation of innate immune responseGO:0045089800.511
gtp catabolic processGO:00061841430.511
cytoplasmic transportGO:00164822340.510
t cell differentiation in thymusGO:0033077770.505
regulation of leukocyte proliferationGO:00706631210.491
Human
alpha beta t cell differentiationGO:0046632690.481
guanosine containing compound catabolic processGO:19010691440.479
b cell receptor signaling pathwayGO:0050853200.469
positive t cell selectionGO:0043368230.468
negative regulation of protein metabolic processGO:00512482820.456
positive regulation of calcium mediated signalingGO:0050850150.446
negative regulation of t cell mediated cytotoxicityGO:000191530.442
regulation of cytokine biosynthetic processGO:0042035590.437
regulation of alpha beta t cell activationGO:0046634530.433
regulation of t cell proliferationGO:0042129920.430
cellular amine metabolic processGO:0044106440.430
release of sequestered calcium ion into cytosolGO:0051209420.429
regulation of t cell activationGO:00508631700.421
lipid biosynthetic processGO:00086101790.418
leukocyte cell cell adhesionGO:0007159140.410
regulation of leukocyte differentiationGO:19021051590.409
regulation of mast cell activationGO:0033003210.406
positive regulation of cytokine biosynthetic processGO:0042108400.406
cytokine metabolic processGO:0042107710.405
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.404
production of molecular mediator of immune responseGO:00024401030.399
ribonucleoside triphosphate metabolic processGO:00091992200.399
regulation of t cell differentiationGO:0045580830.396
organic cyclic compound catabolic processGO:19013612950.395
b cell proliferationGO:0042100530.394
leukocyte differentiationGO:00025213420.394
negative regulation of cellular component organizationGO:00511291940.384
positive regulation of alpha beta t cell activationGO:0046635390.377
positive regulation of interleukin 10 secretionGO:200118110.377
positive regulation of cell activationGO:00508671580.375
cellular amino acid metabolic processGO:00065201030.372
regulation of hydrolase activityGO:00513362460.369
ribonucleoside triphosphate catabolic processGO:00092031990.369
cytokine productionGO:00018163190.363
positive regulation of t cell activationGO:00508701010.363
adaptive immune responseGO:00022501550.358
positive regulation of t cell differentiationGO:0045582520.356
lymphocyte activation involved in immune responseGO:0002285930.356
regulation of cellular ketone metabolic processGO:0010565660.356
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.349
purine ribonucleoside triphosphate catabolic processGO:00092071990.339
positive regulation of gtp catabolic processGO:0033126850.337
innate immune response activating signal transductionGO:0002758500.334
rho protein signal transductionGO:0007266320.334
lymphocyte differentiationGO:00300982420.334
nucleoside catabolic processGO:00091642060.333
cytokine biosynthetic processGO:0042089680.327
purine ribonucleoside triphosphate metabolic processGO:00092052200.324
protein maturationGO:00516041760.324
establishment of protein localization to organelleGO:00725941180.322
ribonucleoside catabolic processGO:00424542060.321
regulation of lymphocyte mediated immunityGO:0002706840.321
small gtpase mediated signal transductionGO:0007264970.317
regulation of alpha beta t cell proliferationGO:0046640180.312
regulation of ras protein signal transductionGO:00465781140.312
positive regulation of t helper 2 cell cytokine productionGO:200055330.310
regulation of cellular amino acid metabolic processGO:000652150.310
cd4 positive alpha beta t cell cytokine productionGO:003574340.307
guanosine containing compound metabolic processGO:19010681440.303
defense response to bacteriumGO:00427421190.297
alpha beta t cell differentiation involved in immune responseGO:0002293300.295
response to granulocyte macrophage colony stimulating factorGO:009701230.294
purine ribonucleotide metabolic processGO:00091502900.291
actin filament organizationGO:00070151130.281
single organismal cell cell adhesionGO:00163371310.281
reactive oxygen species metabolic processGO:0072593840.279
cell adhesionGO:00071553290.278
regulation of insulin receptor signaling pathwayGO:0046626210.277
negative thymic t cell selectionGO:0045060120.275
glycosyl compound catabolic processGO:19016582060.274
nucleoside phosphate metabolic processGO:00067533380.272
nitrogen compound transportGO:00717052710.270
purine nucleotide catabolic processGO:00061952110.270
organonitrogen compound catabolic processGO:19015652640.268
t cell mediated immunityGO:0002456500.267
homeostasis of number of cellsGO:00488722100.264
regulation of gtp catabolic processGO:00331241130.264
cellular ketone metabolic processGO:0042180840.263
nucleocytoplasmic transportGO:00069131390.263
positive regulation of t cell mediated immunityGO:0002711240.261
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic processGO:004542520.259
organelle fusionGO:0048284280.259
female gamete generationGO:0007292740.252
purine ribonucleotide catabolic processGO:00091542080.252
purine containing compound metabolic processGO:00725213110.248
ral protein signal transductionGO:003248420.245
plasma membrane organizationGO:0007009900.244
regulation of leukocyte mediated immunityGO:00027031040.243
cellular lipid metabolic processGO:00442553230.242
regulation of t helper 2 cell cytokine productionGO:200055130.241
negative regulation of cellular protein metabolic processGO:00322692470.239
regulation of rho protein signal transductionGO:0035023710.239
interleukin 10 secretionGO:007260840.237
lymphocyte mediated immunityGO:00024491390.234
membrane tubulationGO:009732040.233
leukocyte activation involved in immune responseGO:00023661260.232
protein localization to membraneGO:00726571080.231
positive regulation of cytokine productionGO:00018191740.230
regulation of purine nucleotide catabolic processGO:00331211220.228
nucleoside metabolic processGO:00091162460.225
regulation of nucleotide catabolic processGO:00308111220.225
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.224
establishment of organelle localizationGO:00516561220.221
positive regulation of cell deathGO:00109422240.220
purine nucleoside catabolic processGO:00061522050.220
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.218
positive regulation of defense responseGO:00313491240.213
positive regulation of programmed cell deathGO:00430682180.211
negative regulation of cellular amino acid metabolic processGO:004576300.211
protein processingGO:00164851630.210
purine nucleoside triphosphate catabolic processGO:00091462030.209
organophosphate catabolic processGO:00464342320.207
t cell activation involved in immune responseGO:0002286430.205
nucleotide metabolic processGO:00091173320.205
positive regulation of gtpase activityGO:0043547850.205
positive regulation of leukocyte proliferationGO:0070665730.205
c4 dicarboxylate transportGO:001574030.204
cd4 positive alpha beta t cell activationGO:0035710450.203
ossificationGO:00015032160.203
protein import into nucleusGO:0006606950.202
positive regulation of hydrolase activityGO:00513451480.200
vesicle fusionGO:0006906160.200
positive thymic t cell selectionGO:0045059130.198
regulation of cellular amine metabolic processGO:0033238200.197
positive regulation of intracellular transportGO:0032388700.197
inflammatory responseGO:00069542440.196
t helper cell differentiationGO:0042093280.196
regulation of cell adhesionGO:00301551540.195
labyrinthine layer blood vessel developmentGO:0060716210.193
positive regulation of lymphocyte differentiationGO:0045621610.193
regulation of response to woundingGO:19030341890.191
positive regulation of t cell cytokine productionGO:000272650.191
negative regulation of adaptive immune responseGO:0002820250.191
cd4 positive alpha beta t cell differentiationGO:0043367410.190
regulation of granulocyte macrophage colony stimulating factor biosynthetic processGO:004542320.189
negative regulation of peptidyl tyrosine phosphorylationGO:0050732170.189
glycosyl compound metabolic processGO:19016572460.188
purine containing compound catabolic processGO:00725232130.187
positive regulation of adaptive immune responseGO:0002821610.187
microtubule based processGO:00070172360.186
interleukin 2 biosynthetic processGO:0042094150.186
regulation of protein localizationGO:00328802310.185
vesicle organizationGO:0016050600.184
regulation of release of cytochrome c from mitochondriaGO:0090199110.183
positive regulation of rho gtpase activityGO:0032321410.182
regulation of lymphocyte differentiationGO:00456191070.181
nucleoside phosphate catabolic processGO:19012922220.181
response to organic cyclic compoundGO:00140701980.181
purine nucleotide metabolic processGO:00061633020.180
t cell differentiation involved in immune responseGO:0002292300.179
regulation of actin polymerization or depolymerizationGO:0008064450.178
negative regulation of phosphorylationGO:00423261660.177
regulation of mitochondrion organizationGO:0010821270.176
regulation of vesicle mediated transportGO:00606271390.175
negative regulation of protein phosphorylationGO:00019331260.173
positive regulation of response to woundingGO:1903036660.172
negative regulation of phosphate metabolic processGO:00459361840.172
peptidyl amino acid modificationGO:00181933360.171
regulation of protein maturationGO:1903317960.171
regulation of interleukin 2 productionGO:0032663280.170
single organism nuclear importGO:1902593950.169
leukocyte proliferationGO:00706611720.168
Human
negative regulation of insulin receptor signaling pathwayGO:0046627140.168
carboxylic acid transportGO:00469421000.168
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002823230.168
interleukin 4 productionGO:0032633240.167
purine nucleoside metabolic processGO:00422782410.164
regulation of ral gtpase activityGO:003231540.164
positive regulation of lymphocyte proliferationGO:0050671700.163
ribose phosphate metabolic processGO:00196932910.162
lymphocyte proliferationGO:00466511640.160
Human
b cell apoptotic processGO:0001783190.160
carbohydrate derivative catabolic processGO:19011362310.160
negative regulation of b cell proliferationGO:0030889130.158
nucleotide catabolic processGO:00091662170.158
negative regulation of hydrolase activityGO:0051346710.157
response to oxidative stressGO:00069791230.153
positive regulation of nucleotide catabolic processGO:0030813880.153
toll like receptor signaling pathwayGO:0002224380.152
immunoglobulin productionGO:0002377730.151
regulation of lymphocyte proliferationGO:00506701170.151
Human
positive regulation of immune effector processGO:00026991070.150
positive regulation of lymphocyte mediated immunityGO:0002708620.150
regulation of blood coagulationGO:0030193280.149
heterocycle catabolic processGO:00467002800.148
regulation of cd4 positive alpha beta t cell activationGO:2000514240.147
g protein coupled receptor signaling pathwayGO:00071862430.147
ceramide biosynthetic processGO:0046513200.147
second messenger mediated signalingGO:0019932730.147
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.146
organelle localizationGO:00516401790.145
b cell activationGO:00421131610.145
positive regulation of gamma delta t cell activationGO:004664560.144
myeloid cell homeostasisGO:00022621140.143
regulation of cysteine type endopeptidase activityGO:2000116650.142
b cell differentiationGO:0030183780.141
alpha beta t cell activationGO:0046631910.140
regulation of actin cytoskeleton organizationGO:0032956840.138
activation of immune responseGO:00022531380.138
exocytosisGO:00068871210.137
regulation of ras gtpase activityGO:0032318880.136
purine nucleoside triphosphate metabolic processGO:00091442260.136
thymic t cell selectionGO:0045061220.136
regulation of interferon gamma productionGO:0032649570.136
labyrinthine layer developmentGO:0060711490.136
peptidyl serine phosphorylationGO:0018105740.134
positive regulation of interleukin 5 secretionGO:200066410.134
granulocyte activationGO:0036230100.132
protein importGO:00170381010.131
regulation of cell activationGO:00508652890.130
natural killer cell activationGO:0030101440.130
Human
cellular response to cytokine stimulusGO:00713451890.130
gtp metabolic processGO:00460391440.129
regulation of b cell proliferationGO:0030888390.128
positive regulation of kinase activityGO:00336741550.127
positive regulation of lymphocyte activationGO:00512511400.127
regulation of vesicle fusionGO:003133860.127
nucleoside triphosphate catabolic processGO:00091432050.126
regulation of defense responseGO:00313472330.126
regulation of superoxide metabolic processGO:009032280.125
regulation of intracellular protein transportGO:0033157820.124
negative regulation of protein maturationGO:1903318790.124
regulation of establishment of protein localizationGO:00702011810.124
purine ribonucleoside metabolic processGO:00461282410.124
regulation of secretionGO:00510462740.124
intracellular protein transportGO:00068862040.123
sphingolipid catabolic processGO:003014970.122
nucleoside triphosphate metabolic processGO:00091412300.122
positive regulation of t cell proliferationGO:0042102520.121
regulation of ion transportGO:00432692150.120
response to peptideGO:19016521360.120
apoptotic mitochondrial changesGO:0008637480.119
negative regulation of phosphorus metabolic processGO:00105631840.119
b cell homeostasisGO:0001782340.119
interleukin 10 productionGO:0032613230.118
membrane fusionGO:0061025380.118
t cell selectionGO:0045058340.117
membrane organizationGO:00610242450.117
regulation of secretion by cellGO:19035302490.117
mast cell mediated immunityGO:0002448200.117
positive regulation of ras gtpase activityGO:0032320650.116
regulation of hemostasisGO:1900046280.114
regulation of b cell differentiationGO:0045577230.114
regulation of kinase activityGO:00435492490.114
regulation of interleukin 2 biosynthetic processGO:0045076130.112
sphingolipid metabolic processGO:0006665450.110
t cell activationGO:00421102890.110
regulation of interleukin 10 productionGO:0032653210.109
regulation of adaptive immune responseGO:0002819900.109
extrinsic apoptotic signaling pathwayGO:00971911260.109
ribonucleoside metabolic processGO:00091192450.108
nuclear importGO:0051170950.108
ribonucleotide metabolic processGO:00092592910.108
glial cell developmentGO:0021782540.108
purine ribonucleoside catabolic processGO:00461302050.108
oocyte differentiationGO:0009994350.107
positive regulation of apoptotic signaling pathwayGO:2001235950.107
antigen receptor mediated signaling pathwayGO:0050851640.107
protein secretionGO:00093061110.106
vesicle localizationGO:0051648860.106
positive regulation of cytokine secretionGO:0050715410.106
insulin receptor signaling pathwayGO:0008286490.105
peptidyl serine modificationGO:0018209830.105
positive regulation of t helper 2 cell activationGO:200057020.105
granulocyte chemotaxisGO:0071621390.104
negative regulation of immune system processGO:00026832090.104
ceramide metabolic processGO:0006672310.103
regulation of cellular response to stressGO:00801351590.101
positive regulation of leukocyte mediated immunityGO:0002705700.100
positive regulation of interleukin 2 biosynthetic processGO:004508680.097
protein autophosphorylationGO:0046777610.097
positive regulation of nucleoside metabolic processGO:0045979910.097
response to inorganic substanceGO:0010035960.096
developmental maturationGO:00217001930.096
nucleobase containing small molecule metabolic processGO:00550863520.096
regulation of interleukin 10 secretionGO:200117940.096
positive regulation of interleukin 13 secretionGO:200066710.095
mitochondrion organizationGO:00070051340.095
regulation of purine nucleotide metabolic processGO:19005421690.094
endocytosisGO:00068971680.093
positive regulation of cellular catabolic processGO:00313311480.092
activation of jun kinase activityGO:0007257150.092
regulation of ral protein signal transductionGO:003248540.092
calcium mediated signalingGO:0019722460.092
interleukin 5 secretionGO:007260320.090
organic anion transportGO:00157111370.090
regulation of intracellular transportGO:00323861590.090
regulation of nucleoside metabolic processGO:00091181300.089
symbiosis encompassing mutualism through parasitismGO:0044403830.089
positive regulation of protein modification processGO:00314012990.086
regulation of transferase activityGO:00513382630.086
positive regulation of purine nucleotide catabolic processGO:0033123880.086
immune response activating cell surface receptor signaling pathwayGO:0002429720.086
regulation of cell migrationGO:00303342190.086
sphingolipid biosynthetic processGO:0030148260.085
anion transportGO:00068201770.085
regulation of rho gtpase activityGO:0032319580.085
membrane lipid biosynthetic processGO:0046467320.085
peptidyl threonine modificationGO:0018210310.085
endomembrane system organizationGO:00102561470.084
regulation of organelle organizationGO:00330432890.084
interaction with hostGO:0051701220.084
positive regulation of b cell differentiationGO:0045579130.083
regulation of phospholipid catabolic processGO:006069620.083
positive regulation of secretion by cellGO:19035321140.082
innate immune responseGO:00450871570.082
cell type specific apoptotic processGO:00972852680.082
myeloid leukocyte migrationGO:0097529570.082
immunoglobulin mediated immune responseGO:0016064690.081
positive regulation of protein serine threonine kinase activityGO:00719021060.081
amide transportGO:00428861380.081
marginal zone b cell differentiationGO:000231520.080
placenta developmentGO:00018901400.080
cellular response to growth factor stimulusGO:00713631970.080
apoptotic signaling pathwayGO:00971903060.079
granulocyte macrophage colony stimulating factor productionGO:003260430.079
regulation of interleukin 4 productionGO:0032673180.079
activation of ras gtpase activityGO:0032856110.078
regulation of peptidyl tyrosine phosphorylationGO:0050730930.078
immune complex clearanceGO:000243420.078
calcium ion transportGO:00068161590.077
aromatic compound catabolic processGO:00194392860.077
myeloid cell activation involved in immune responseGO:0002275340.076
regulation of cytokine production involved in immune responseGO:0002718260.076
regulation of reactive oxygen species metabolic processGO:2000377400.075
positive regulation of leukocyte differentiationGO:1902107860.075
regulation of protein kinase activityGO:00458592320.075
sequestering of calcium ionGO:0051208180.075
regulation of t cell mediated immunityGO:0002709340.075
neutrophil chemotaxisGO:0030593360.074
regulation of granulocyte macrophage colony stimulating factor productionGO:003264530.074
granulocyte migrationGO:0097530430.073
granulocyte macrophage colony stimulating factor biosynthetic processGO:004225320.073
protein localization to organelleGO:00333651850.073
microtubule cytoskeleton organizationGO:00002261570.072
regulation of metal ion transportGO:00109591060.072
regulation of synaptic growth at neuromuscular junctionGO:000858240.072
positive regulation of killing of cells of other organismGO:005171230.071
regulation of innate immune responseGO:0045088910.071
negative regulation of cell adhesionGO:0007162450.070
regulation of cd4 positive alpha beta t cell differentiationGO:0043370210.070
positive regulation of purine nucleotide metabolic processGO:19005441140.070
membrane lipid metabolic processGO:0006643530.069
cellular response to molecule of fungal originGO:007122620.069
inorganic ion transmembrane transportGO:00986602340.069
regulation of interleukin 5 secretionGO:200066220.069
phospholipid metabolic processGO:0006644870.068
regulation of apoptotic signaling pathwayGO:20012331970.068
muscle cell differentiationGO:00426922610.068
response to endoplasmic reticulum stressGO:0034976530.068
response to drugGO:0042493750.067
homotypic cell cell adhesionGO:0034109280.067
regulation of gamma delta t cell differentiationGO:004558690.067
intracellular mrna localizationGO:000829840.067
regulation of b cell activationGO:0050864810.067
generation of precursor metabolites and energyGO:00060911030.067
b cell mediated immunityGO:0019724710.066
cellular response to molecule of bacterial originGO:0071219830.066
monocarboxylic acid biosynthetic processGO:0072330610.066
negative regulation of intracellular signal transductionGO:19025321670.066
regulation of mapk cascadeGO:00434082480.066
establishment or maintenance of cytoskeleton polarityGO:003095220.065
i kappab kinase nf kappab signalingGO:0007249850.065
interspecies interaction between organismsGO:0044419830.065
positive regulation of homeostatic processGO:0032846640.065
neuronal action potentialGO:0019228540.064
positive regulation of vesicle fusionGO:003134020.064
regulation of peptidase activityGO:0052547960.064
regulation of cytoskeleton organizationGO:00514931220.064
peptidyl tyrosine modificationGO:00182121450.064
actin filament polymerizationGO:0030041440.063
divalent metal ion transportGO:00708381720.063
humoral immune responseGO:0006959570.063
regulation of neutrophil differentiationGO:004565820.063
alpha beta t cell activation involved in immune responseGO:0002287310.063
positive regulation of interleukin 5 productionGO:003275450.062
regulation of cell shapeGO:0008360390.062
glycogen cell differentiation involved in embryonic placenta developmentGO:006070910.062
response to ethanolGO:0045471180.061
myeloid leukocyte mediated immunityGO:0002444420.061
superoxide metabolic processGO:0006801270.061
neutrophil activationGO:004211990.061
negative regulation of b cell mediated immunityGO:000271370.061
oocyte constructionGO:000730820.061
regulation of cellular component sizeGO:00325351210.061
regulation of proteolysisGO:00301621640.060
positive regulation of interleukin 10 productionGO:0032733120.059
inositol lipid mediated signalingGO:0048017410.059
regulation of cellular component biogenesisGO:00440871810.059
regulation of exocytosisGO:0017157610.059
interleukin 3 productionGO:003263230.058
glucose metabolic processGO:0006006920.058
t helper 2 cell activationGO:003571220.058
positive regulation of type 2 immune responseGO:000283090.057
regulation of mast cell degranulationGO:0043304160.057
negative regulation of protein processingGO:0010955790.057
sensory organ morphogenesisGO:00905962420.057
tissue homeostasisGO:00018941150.057
positive regulation of protein phosphorylationGO:00019342420.057
regulation of interleukin 13 secretionGO:200066520.057
mammary gland epithelium developmentGO:0061180650.057
negative regulation of leukocyte mediated immunityGO:0002704290.057
regulation of wound healingGO:0061041400.056
extracellular structure organizationGO:00430621480.056
regulation of cytokine secretionGO:0050707610.056
autophagyGO:0006914450.056
regulation of body fluid levelsGO:00508781620.056
regulation of sphingolipid biosynthetic processGO:009015310.055
cellular response to nutrient levelsGO:0031669640.055
regulation of protein transportGO:00512231630.055
regulation of protein homooligomerizationGO:003246230.054
hematopoietic progenitor cell differentiationGO:00022441430.054
cellular biogenic amine metabolic processGO:0006576280.054
regulation of coagulationGO:0050818310.053
protein targetingGO:00066051430.053
organic hydroxy compound metabolic processGO:19016152030.053
synaptic transmissionGO:00072683290.053
negative regulation of cell adhesion involved in substrate bound cell migrationGO:000693330.052
negative regulation of protein modification processGO:00314001630.051
positive regulation of proteolysisGO:0045862850.051
hexose metabolic processGO:0019318980.051
regulation of cell killingGO:0031341400.051
organic acid biosynthetic processGO:0016053860.051
lateral inhibitionGO:004633110.051
coagulationGO:0050817780.050
germ cell developmentGO:00072811850.050
regulation of protein autophosphorylationGO:003195280.050
response to reactive oxygen speciesGO:0000302560.050
positive regulation of protein targeting to membraneGO:009031470.050
regulation of endopeptidase activityGO:0052548890.050
negative regulation of endopeptidase activityGO:0010951440.049
positive regulation of ral gtpase activityGO:003285240.049
positive regulation of protein kinase activityGO:00458601440.049
regulation of cell cycleGO:00517262810.048
myeloid cell differentiationGO:00300992330.048
regulation of multi organism processGO:00439001110.048
oocyte axis specificationGO:000730920.048
negative regulation of endocytosisGO:0045806120.048
leukocyte apoptotic processGO:0071887710.048
cellular response to organonitrogen compoundGO:00714171450.048
oocyte anterior posterior axis specificationGO:000731420.047
negative regulation of peptidase activityGO:0010466460.047
carboxylic acid biosynthetic processGO:0046394860.047
cellular amide metabolic processGO:0043603580.047
positive regulation of b cell activationGO:0050871490.047
positive regulation of organelle organizationGO:00106381280.046
myotube differentiationGO:00149021050.046
positive regulation of alpha beta t cell proliferationGO:0046641120.046
mapk cascadeGO:00001652810.046
leukotriene biosynthetic processGO:001937050.046
eye photoreceptor cell differentiationGO:0001754410.045
blood coagulationGO:0007596760.045
negative regulation of release of cytochrome c from mitochondriaGO:009020160.045
lipid transportGO:0006869980.045
leukocyte migrationGO:00509001240.045

Ptpn22 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:291400.921
Human
disease of anatomical entityDOID:700.921
Human
musculoskeletal system diseaseDOID:1700.253
Human
hematopoietic system diseaseDOID:7400.199
primary immunodeficiency diseaseDOID:61200.124
blood protein diseaseDOID:62000.124
agammaglobulinemiaDOID:258300.124
common variable immunodeficiencyDOID:1217700.124
b cell deficiencyDOID:211500.124
hypersensitivity reaction diseaseDOID:006005600.094
Human
lupus erythematosusDOID:885700.080
Human
hypersensitivity reaction type ii diseaseDOID:41700.080
Human
connective tissue diseaseDOID:6500.073
Human