IMP: Integrative Multi-species Prediction

Mus musculus

75 known processes

Pxmp3

peroxisomal membrane protein 3

(Aliases: D3Ertd138e,PMP35,Pex2,35kDa)

Entrez: 19302
Ensembl: ENSMUSG00000040374
UniProtKB: P55098
UniProtKB: Q91YZ5

Process Predictions
Disease Predictions

Pxmp3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
protein localization to peroxisome	GO:0072662	4	0.226	Human Fly
establishment of protein localization to peroxisome	GO:0072663	4	0.195	Human Fly
peroxisomal transport	GO:0043574	4	0.174	Human Fly
protein targeting to peroxisome	GO:0006625	4	0.147	Human Fly
intra golgi vesicle mediated transport	GO:0006891	1	0.059
protein localization to membrane	GO:0072657	108	0.059
cellular lipid metabolic process	GO:0044255	323	0.057	Human
glycosyl compound metabolic process	GO:1901657	246	0.054
intracellular protein transport	GO:0006886	204	0.054	Human Fly
ion transmembrane transport	GO:0034220	361	0.053
cellular homeostasis	GO:0019725	240	0.051
nucleoside phosphate metabolic process	GO:0006753	338	0.050
nucleotide metabolic process	GO:0009117	332	0.049
regulation of hormone levels	GO:0010817	211	0.049
regulation of lipid metabolic process	GO:0019216	118	0.047
organonitrogen compound biosynthetic process	GO:1901566	192	0.046
protein import into peroxisome matrix	GO:0016558	3	0.046	Human Fly
endomembrane system organization	GO:0010256	147	0.045
protein targeting	GO:0006605	143	0.045	Human Fly
nucleobase containing small molecule metabolic process	GO:0055086	352	0.043
membrane lipid metabolic process	GO:0006643	53	0.043
embryonic organ morphogenesis	GO:0048562	276	0.042
lipid biosynthetic process	GO:0008610	179	0.039
membrane organization	GO:0061024	245	0.038
transmembrane transport	GO:0055085	412	0.038	Human Fly
retrograde vesicle mediated transport golgi to er	GO:0006890	1	0.036
gland development	GO:0048732	330	0.036
organic hydroxy compound metabolic process	GO:1901615	203	0.033
purine containing compound metabolic process	GO:0072521	311	0.032
sphingolipid metabolic process	GO:0006665	45	0.031
cellular amino acid metabolic process	GO:0006520	103	0.031
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.030
regulation of sphingolipid biosynthetic process	GO:0090153	1	0.029
regulation of vesicle mediated transport	GO:0060627	139	0.029
aromatic compound catabolic process	GO:0019439	286	0.027
membrane lipid biosynthetic process	GO:0046467	32	0.027
cellular nitrogen compound catabolic process	GO:0044270	280	0.026
nitrogen compound transport	GO:0071705	271	0.026
plasma membrane organization	GO:0007009	90	0.025
ribonucleotide metabolic process	GO:0009259	291	0.025
cation homeostasis	GO:0055080	212	0.024
ribose phosphate metabolic process	GO:0019693	291	0.023
organophosphate catabolic process	GO:0046434	232	0.023
regulation of intracellular protein transport	GO:0033157	82	0.021
cellular amine metabolic process	GO:0044106	44	0.020
nucleoside phosphate catabolic process	GO:1901292	222	0.020
negative regulation of golgi to plasma membrane protein transport	GO:0042997	3	0.020
ribonucleoside metabolic process	GO:0009119	245	0.019
hormone secretion	GO:0046879	128	0.019
divalent inorganic cation transport	GO:0072511	178	0.019
cytoplasmic transport	GO:0016482	234	0.018	Human Fly
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.018
protein processing	GO:0016485	163	0.018
anion transport	GO:0006820	177	0.018
leukocyte differentiation	GO:0002521	342	0.018
skeletal system development	GO:0001501	356	0.017
metal ion homeostasis	GO:0055065	189	0.017
cellular chemical homeostasis	GO:0055082	215	0.017
regulation of toll like receptor 9 signaling pathway	GO:0034163	3	0.017
regulation of secretion by cell	GO:1903530	249	0.017
purine nucleoside metabolic process	GO:0042278	241	0.017
organic acid catabolic process	GO:0016054	51	0.017	Human
response to topologically incorrect protein	GO:0035966	25	0.016
maintenance of location	GO:0051235	89	0.015
digestive tract morphogenesis	GO:0048546	147	0.015
regulation of er to golgi vesicle mediated transport	GO:0060628	4	0.015
negative regulation of cellular component organization	GO:0051129	194	0.015
protein localization to organelle	GO:0033365	185	0.015	Human Fly
amide transport	GO:0042886	138	0.015
monocarboxylic acid metabolic process	GO:0032787	191	0.015
response to inorganic substance	GO:0010035	96	0.015
oxidation reduction process	GO:0055114	342	0.015	Human
organic cyclic compound catabolic process	GO:1901361	295	0.015
vesicle organization	GO:0016050	60	0.015
regulation of cellular component biogenesis	GO:0044087	181	0.015
positive regulation of secretion	GO:0051047	130	0.015
atp metabolic process	GO:0046034	75	0.015
protein localization to nuclear envelope	GO:0090435	2	0.014
regulation of protein localization	GO:0032880	231	0.014
glycerophospholipid metabolic process	GO:0006650	71	0.014
heart process	GO:0003015	94	0.014
heterocycle catabolic process	GO:0046700	280	0.014
nucleoside monophosphate metabolic process	GO:0009123	85	0.014
circulatory system process	GO:0003013	197	0.014
dephosphorylation	GO:0016311	129	0.014
myeloid cell differentiation	GO:0030099	233	0.014
camera type eye development	GO:0043010	266	0.014
macromolecule catabolic process	GO:0009057	281	0.014
mitochondrion organization	GO:0007005	134	0.014
nucleoside metabolic process	GO:0009116	246	0.013
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.013
organophosphate ester transport	GO:0015748	28	0.013
negative regulation of immune system process	GO:0002683	209	0.013
blood circulation	GO:0008015	195	0.013
ossification	GO:0001503	216	0.013
lipid homeostasis	GO:0055088	63	0.013
peptide secretion	GO:0002790	114	0.013
regulation of cytoplasmic transport	GO:1903649	112	0.012
carbohydrate derivative catabolic process	GO:1901136	231	0.012
forebrain development	GO:0030900	302	0.012
purine ribonucleoside metabolic process	GO:0046128	241	0.012
ubiquitin dependent protein catabolic process	GO:0006511	129	0.012
cellular metal ion homeostasis	GO:0006875	151	0.012
protein maturation	GO:0051604	176	0.012
golgi vesicle transport	GO:0048193	30	0.012
alcohol metabolic process	GO:0006066	116	0.012
anion transmembrane transport	GO:0098656	71	0.012
regulation of lipid biosynthetic process	GO:0046890	54	0.012
lipid modification	GO:0030258	65	0.012	Human
regulation of secretion	GO:0051046	274	0.012
phospholipid metabolic process	GO:0006644	87	0.012
cellular macromolecule catabolic process	GO:0044265	206	0.012
regulation of nucleotide metabolic process	GO:0006140	169	0.011
multicellular organism growth	GO:0035264	161	0.011	Worm
peptidyl lysine modification	GO:0018205	77	0.011
positive regulation of secretion by cell	GO:1903532	114	0.011
organophosphate biosynthetic process	GO:0090407	122	0.011
carboxylic acid catabolic process	GO:0046395	51	0.011	Human
sensory organ morphogenesis	GO:0090596	242	0.011
purine nucleotide metabolic process	GO:0006163	302	0.011
negative regulation of organelle organization	GO:0010639	90	0.011
organonitrogen compound catabolic process	GO:1901565	264	0.011
small molecule catabolic process	GO:0044282	71	0.011	Human
response to organic cyclic compound	GO:0014070	198	0.011
purine nucleoside monophosphate metabolic process	GO:0009126	81	0.011
ribonucleoside monophosphate metabolic process	GO:0009161	80	0.011
divalent metal ion transport	GO:0070838	172	0.011
ceramide metabolic process	GO:0006672	31	0.011
amine metabolic process	GO:0009308	45	0.010
carbohydrate derivative biosynthetic process	GO:1901137	183	0.010
negative regulation of lipid metabolic process	GO:0045833	30	0.010
cellular ketone metabolic process	GO:0042180	84	0.010
protein localization to plasma membrane	GO:0072659	57	0.010
purine ribonucleotide metabolic process	GO:0009150	290	0.010
regulation of hydrolase activity	GO:0051336	246	0.010

Pxmp3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
inherited metabolic disorder	DOID:655	0.030
disease of metabolism	DOID:0014667	0.030
carbohydrate metabolic disorder	DOID:2978	0.025

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