Mus musculus

155 known processes

Pxn

paxillin

(Aliases: Pax,AW123232,AW108311)

Pxn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
adherens junction assemblyGO:0034333220.998
focal adhesion assemblyGO:0048041190.984
cell junction assemblyGO:0034329520.975
cell cell junction organizationGO:0045216720.974
cell substrate adhesionGO:00315891300.960
cell matrix adhesionGO:0007160680.957
substrate adhesion dependent cell spreadingGO:0034446300.952
single organism cell adhesionGO:00986021560.949
cell junction organizationGO:0034330770.941
ras protein signal transductionGO:0007265770.919
adherens junction organizationGO:0034332280.912
cell adhesionGO:00071553290.909
lamellipodium organizationGO:0097581290.906
gtp metabolic processGO:00460391440.902
Fly
small gtpase mediated signal transductionGO:0007264970.900
cell substrate adherens junction assemblyGO:0007045190.893
heterocycle catabolic processGO:00467002800.872
Fly
guanosine containing compound metabolic processGO:19010681440.868
Fly
purine nucleotide catabolic processGO:00061952110.854
Fly
regulation of nucleotide catabolic processGO:00308111220.850
Fly
cell substrate junction assemblyGO:0007044240.844
actin filament organizationGO:00070151130.809
regulation of lamellipodium morphogenesisGO:200039210.808
regulation of cell migrationGO:00303342190.803
single organismal cell cell adhesionGO:00163371310.787
Mouse
negative regulation of synapse assemblyGO:005196430.782
positive regulation of rho gtpase activityGO:0032321410.738
regulation of actin filament based processGO:0032970990.720
gtp catabolic processGO:00061841430.716
Fly
negative regulation of phosphorylationGO:00423261660.685
positive regulation of cell projection organizationGO:0031346950.672
immune response regulating signaling pathwayGO:00027641250.670
regulation of nucleotide metabolic processGO:00061401690.654
Fly
regulation of cell motilityGO:20001452360.651
immune response activating signal transductionGO:00027571160.643
purine containing compound catabolic processGO:00725232130.643
Fly
lamellipodium morphogenesisGO:007267350.639
regulation of cytoskeleton organizationGO:00514931220.629
guanosine containing compound catabolic processGO:19010691440.623
Fly
integrin mediated signaling pathwayGO:0007229270.616
nucleoside catabolic processGO:00091642060.608
Fly
purine ribonucleoside triphosphate catabolic processGO:00092071990.599
Fly
regulation of cellular amino acid metabolic processGO:000652150.596
peptidyl serine modificationGO:0018209830.589
actin cytoskeleton organizationGO:00300362200.588
Mouse
ribonucleoside triphosphate catabolic processGO:00092031990.575
Fly
regulation of organelle organizationGO:00330432890.570
purine ribonucleoside catabolic processGO:00461302050.563
Fly
negative regulation of transferase activityGO:0051348850.561
actin filament bundle assemblyGO:0051017400.557
purine nucleoside triphosphate catabolic processGO:00091462030.551
Fly
regulation of cellular catabolic processGO:00313292420.550
Fly
alpha beta t cell differentiationGO:0046632690.549
mapk cascadeGO:00001652810.545
glycosyl compound metabolic processGO:19016572460.543
Fly
positive regulation of nucleoside metabolic processGO:0045979910.538
positive regulation of gtpase activityGO:0043547850.533
regulation of gtp catabolic processGO:00331241130.518
Fly
positive regulation of cell adhesionGO:0045785800.517
purine nucleoside catabolic processGO:00061522050.507
Fly
nucleotide catabolic processGO:00091662170.501
Fly
positive regulation of glial cell proliferationGO:006025240.500
negative regulation of anoikisGO:200081120.498
ribonucleoside catabolic processGO:00424542060.495
Fly
glycosyl compound catabolic processGO:19016582060.491
Fly
positive regulation of nucleotide catabolic processGO:0030813880.487
regulation of cell adhesionGO:00301551540.484
organonitrogen compound catabolic processGO:19015652640.483
Fly
ribonucleoside triphosphate metabolic processGO:00091992200.482
Fly
protein catabolic processGO:00301632210.473
regulation of nucleoside metabolic processGO:00091181300.468
Fly
regulation of purine nucleotide metabolic processGO:19005421690.461
Fly
positive regulation of cell developmentGO:00107202370.449
positive regulation of purine nucleotide metabolic processGO:19005441140.447
positive regulation of nervous system developmentGO:00519622210.445
positive regulation of rac gtpase activityGO:0032855140.440
positive regulation of programmed cell deathGO:00430682180.430
purine containing compound metabolic processGO:00725213110.425
Fly
positive regulation of smooth muscle cell migrationGO:001491140.416
ameboidal type cell migrationGO:00016671280.414
i kappab kinase nf kappab signalingGO:0007249850.412
activation of immune responseGO:00022531380.407
regulation of actin cytoskeleton organizationGO:0032956840.406
positive regulation of cell substrate adhesionGO:0010811470.401
regulation of protein autophosphorylationGO:003195280.400
response to growth factorGO:00708481980.399
positive regulation of protein modification processGO:00314012990.390
negative regulation of phosphate metabolic processGO:00459361840.389
regulation of calcium ion transport into cytosolGO:0010522310.389
response to reactive oxygen speciesGO:0000302560.380
Human
ribonucleotide catabolic processGO:00092612080.371
Fly
purine ribonucleotide metabolic processGO:00091502900.371
Fly
negative regulation of phosphorus metabolic processGO:00105631840.367
regulation of anoikisGO:200020920.366
cell growthGO:00160491300.365
purine nucleotide metabolic processGO:00061633020.357
Fly
purine nucleoside metabolic processGO:00422782410.356
Fly
positive regulation of cell motilityGO:20001471160.352
cellular nitrogen compound catabolic processGO:00442702800.351
Fly
nucleoside triphosphate catabolic processGO:00091432050.350
Fly
negative regulation of molecular functionGO:00440922580.347
nucleoside triphosphate metabolic processGO:00091412300.347
Fly
positive regulation of cellular amine metabolic processGO:003324050.343
positive regulation of ras gtpase activityGO:0032320650.343
regulation of cell projection organizationGO:00313442060.343
negative regulation of ras protein signal transductionGO:0046580180.338
peptidyl tyrosine modificationGO:00182121450.337
maintenance of locationGO:0051235890.335
regulation of cytoplasmic transportGO:19036491120.335
cellularizationGO:000734910.334
defense response to other organismGO:00985421970.333
actin polymerization or depolymerizationGO:0008154540.333
ribose phosphate metabolic processGO:00196932910.332
Fly
calcium ion transport into cytosolGO:0060402480.328
ribonucleoside metabolic processGO:00091192450.314
Fly
regulation of protein localizationGO:00328802310.313
nucleobase containing small molecule metabolic processGO:00550863520.308
Fly
negative regulation of protein phosphorylationGO:00019331260.307
negative regulation of apoptotic signaling pathwayGO:20012341040.305
regulation of ion homeostasisGO:2000021640.301
purine ribonucleotide catabolic processGO:00091542080.301
Fly
positive regulation of cell migrationGO:00303351090.299
cellular lipid metabolic processGO:00442553230.298
positive regulation of gtp catabolic processGO:0033126850.298
axonogenesisGO:00074092740.294
negative regulation of protein metabolic processGO:00512482820.289
nucleoside phosphate metabolic processGO:00067533380.289
Fly
negative regulation of cell developmentGO:00107211690.288
regulation of cell morphogenesis involved in differentiationGO:00107691510.287
positive regulation of cell deathGO:00109422240.287
protein autophosphorylationGO:0046777610.284
positive regulation of lipid kinase activityGO:0090218110.279
positive regulation of protein autophosphorylationGO:003195440.279
modification dependent macromolecule catabolic processGO:00436321330.279
gland developmentGO:00487323300.278
Mouse
regulation of kinase activityGO:00435492490.276
regulation of purine nucleotide catabolic processGO:00331211220.273
Fly
membrane organizationGO:00610242450.272
marginal zone b cell differentiationGO:000231520.271
actomyosin structure organizationGO:0031032560.268
actin cytoskeleton reorganizationGO:0031532210.266
positive regulation of hydrolase activityGO:00513451480.263
regulation of mapk cascadeGO:00434082480.260
positive regulation of fibroblast migrationGO:001076350.260
leukocyte cell cell adhesionGO:0007159140.250
amine metabolic processGO:0009308450.249
antigen receptor mediated signaling pathwayGO:0050851640.243
aromatic compound catabolic processGO:00194392860.242
Fly
regulation of mast cell proliferationGO:007066640.240
positive regulation of apoptotic processGO:00430652170.237
nucleoside phosphate catabolic processGO:19012922220.233
Fly
t cell activationGO:00421102890.231
positive regulation of nucleotide metabolic processGO:00459811140.230
macromolecule catabolic processGO:00090572810.224
homotypic cell cell adhesionGO:0034109280.221
cellular amino acid metabolic processGO:00065201030.217
cellular response to hepatocyte growth factor stimulusGO:003572920.216
regulation of hydrolase activityGO:00513362460.215
Fly
response to oxidative stressGO:00069791230.211
Human
negative regulation of kinase activityGO:0033673810.208
phagocytosisGO:0006909660.208
nucleoside metabolic processGO:00091162460.203
Fly
nucleotide metabolic processGO:00091173320.198
Fly
positive regulation of cellular amino acid metabolic processGO:004576430.198
germ cell developmentGO:00072811850.198
Fly
early endosome to late endosome transportGO:004502220.198
cytoplasmic transportGO:00164822340.197
positive regulation of lamellipodium organizationGO:190274530.192
muscle cell developmentGO:00550011330.189
olfactory learningGO:000835520.189
synapse organizationGO:00508081250.187
sequestering of calcium ionGO:0051208180.186
organic cyclic compound catabolic processGO:19013612950.186
Fly
engulfment of apoptotic cellGO:004365230.182
negative regulation of intracellular signal transductionGO:19025321670.182
epithelial cell cell adhesionGO:009013660.181
regulation of developmental pigmentationGO:0048070140.180
negative regulation of cellular protein metabolic processGO:00322692470.180
regulation of cellular component biogenesisGO:00440871810.178
regulation of rho gtpase activityGO:0032319580.178
Fly
establishment or maintenance of cell polarityGO:0007163860.176
Mouse
ribonucleotide metabolic processGO:00092592910.175
Fly
hematopoietic progenitor cell differentiationGO:00022441430.175
regulation of osteoblast differentiationGO:0045667670.173
response to hepatocyte growth factorGO:003572820.173
cellular ketone metabolic processGO:0042180840.172
negative regulation of cellular amino acid metabolic processGO:004576300.170
smooth muscle cell migrationGO:0014909100.167
sequestering of metal ionGO:0051238190.167
cellular response to organonitrogen compoundGO:00714171450.166
Human
t cell differentiationGO:00302171740.165
regulation of stress fiber assemblyGO:0051492150.161
response to molecule of bacterial originGO:00022371430.161
purine nucleoside triphosphate metabolic processGO:00091442260.159
Fly
regulation of substrate adhesion dependent cell spreadingGO:1900024120.157
regulation of cellular ketone metabolic processGO:0010565660.154
regulation of ossificationGO:00302781120.154
apoptotic signaling pathwayGO:00971903060.153
protein localization to organelleGO:00333651850.153
organophosphate catabolic processGO:00464342320.153
Fly
extrinsic apoptotic signaling pathwayGO:00971911260.152
phospholipid metabolic processGO:0006644870.151
negative regulation of map kinase activityGO:0043407340.150
cellular response to ethanolGO:007136130.150
morphogenesis of a polarized epitheliumGO:0001738370.149
regulation of cell adhesion mediated by integrinGO:0033628130.149
regulation of phagocytosisGO:0050764330.148
carbohydrate derivative catabolic processGO:19011362310.147
Fly
cellular response to insulin stimulusGO:0032869780.147
purine ribonucleoside metabolic processGO:00461282410.146
Fly
lymphocyte homeostasisGO:0002260640.145
positive regulation of protein phosphorylationGO:00019342420.144
platelet derived growth factor receptor signaling pathwayGO:0048008320.144
regulation of ras protein signal transductionGO:00465781140.142
Fly
protein localization to plasma membraneGO:0072659570.141
negative regulation of hydrolase activityGO:0051346710.141
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.141
Human
regulation of phospholipase c activityGO:190027430.138
regulation of cell substrate adhesionGO:0010810730.137
cellular response to peptideGO:1901653920.137
Human
regulation of innate immune responseGO:0045088910.137
response to peptide hormoneGO:00434341270.137
Human
regulation of cellular response to stressGO:00801351590.137
fibroblast migrationGO:0010761210.137
positive regulation of innate immune responseGO:0045089800.137
cellular metal ion homeostasisGO:00068751510.135
hepatocyte growth factor receptor signaling pathwayGO:004801230.134
spermatogenesisGO:00072832840.133
stress activated mapk cascadeGO:0051403800.132
peptidyl threonine phosphorylationGO:0018107310.132
cation homeostasisGO:00550802120.131
calcium ion homeostasisGO:00550741270.130
glial cell migrationGO:000834770.126
morphogenesis of a branching epitheliumGO:00611381930.126
leukocyte migrationGO:00509001240.125
positive regulation of purine nucleotide catabolic processGO:0033123880.123
positive regulation of cellular component biogenesisGO:0044089940.123
cellular response to peptide hormone stimulusGO:0071375920.121
Human
regulation of antigen receptor mediated signaling pathwayGO:0050854290.121
formation of primary germ layerGO:0001704770.121
positive regulation of substrate adhesion dependent cell spreadingGO:190002680.119
t cell proliferationGO:00420981200.119
modification dependent protein catabolic processGO:00199411330.118
positive regulation of cellular catabolic processGO:00313311480.117
regulation of transferase activityGO:00513382630.116
developmental cell growthGO:0048588840.115
development of primary sexual characteristicsGO:00451371430.115
transforming growth factor beta receptor signaling pathwayGO:0007179710.115
immune effector processGO:00022523210.114
regulation of proteolysisGO:00301621640.111
regulation of apoptotic signaling pathwayGO:20012331970.110
regulation of cellular component sizeGO:00325351210.109
astrocyte cell migrationGO:004361530.109
cell junction maintenanceGO:003433140.109
peptidyl amino acid modificationGO:00181933360.107
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742400.106
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.106
stress activated protein kinase signaling cascadeGO:0031098810.106
digestive system developmentGO:00551232000.106
regulation of mammary gland epithelial cell proliferationGO:0033599120.105
cellular response to lipopolysaccharideGO:0071222770.105
regulation of actin polymerization or depolymerizationGO:0008064450.102
canonical wnt signaling pathwayGO:00600701300.100
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.099
neuron projection extensionGO:1990138640.098
negative regulation of peptidyl tyrosine phosphorylationGO:0050732170.098
negative regulation of homeostatic processGO:0032845710.097
mesenchymal cell developmentGO:0014031930.097
negative regulation of protein modification processGO:00314001630.097
cellular response to hormone stimulusGO:00328701500.097
Human
regulation of anatomical structure sizeGO:00900661780.096
metal ion homeostasisGO:00550651890.096
microtubule cytoskeleton organizationGO:00002261570.096
negative regulation of protein processingGO:0010955790.096
negative regulation of ossificationGO:0030279490.096
regulation of canonical wnt signaling pathwayGO:0060828820.096
positive regulation of cytoskeleton organizationGO:0051495490.095
negative regulation of peptidase activityGO:0010466460.094
calcium ion transportGO:00068161590.094
cellular response to biotic stimulusGO:0071216920.094
cellular amine metabolic processGO:0044106440.092
regulation of protein complex assemblyGO:0043254830.092
positive regulation of intracellular transportGO:0032388700.092
divalent inorganic cation homeostasisGO:00725071380.091
regulation of membrane potentialGO:00423911920.091
cation transportGO:00068123990.091
positive regulation of mapk cascadeGO:00434101700.091
ubiquitin dependent protein catabolic processGO:00065111290.091
chemotaxisGO:00069352470.090
establishment of protein localization to organelleGO:00725941180.090
actin filament polymerizationGO:0030041440.090
regulation of cellular amine metabolic processGO:0033238200.090
epithelial tube morphogenesisGO:00605623030.089
release of sequestered calcium ion into cytosolGO:0051209420.089
toll like receptor signaling pathwayGO:0002224380.088
regulation of protein transportGO:00512231630.088
nuclear transportGO:00511691390.088
immune response regulating cell surface receptor signaling pathwayGO:0002768800.088
neuron projection regenerationGO:0031102140.087
regulation of defense responseGO:00313472330.087
regulation of establishment of protein localizationGO:00702011810.087
regulation of ras gtpase activityGO:0032318880.086
Fly
response to lipopolysaccharideGO:00324961280.085
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.084
regulation of smooth muscle cell migrationGO:001491060.084
myeloid cell activation involved in immune responseGO:0002275340.083
protein localization to membraneGO:00726571080.082
b cell receptor signaling pathwayGO:0050853200.082
platelet activationGO:0030168400.082
negative regulation of cell proliferationGO:00082852960.081
Mouse
regulation of protein maturationGO:1903317960.081
positive regulation of phospholipase c activityGO:001086320.080
multicellular organismal homeostasisGO:00488711640.079
regulation of dendritic cell apoptotic processGO:200066830.078
regulation of cell projection assemblyGO:0060491380.078
regulation of peptidyl tyrosine phosphorylationGO:0050730930.078
b cell proliferationGO:0042100530.077
negative regulation of cellular component organizationGO:00511291940.077
hexose metabolic processGO:0019318980.077
cellular homeostasisGO:00197252400.076
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.075
regulation of rho protein signal transductionGO:0035023710.075
Fly
digestive tract morphogenesisGO:00485461470.074
endocytosisGO:00068971680.074
endoderm developmentGO:0007492450.074
developmental pigmentationGO:0048066400.073
purine ribonucleoside triphosphate metabolic processGO:00092052200.073
Fly
cell fate commitmentGO:00451652100.073
Mouse
negative regulation of protein tyrosine kinase activityGO:006109930.072
cellular divalent inorganic cation homeostasisGO:00725031270.072
neurotrophin trk receptor signaling pathwayGO:004801180.072
anoikisGO:004327660.072
peptidyl serine phosphorylationGO:0018105740.072
positive regulation of b cell receptor signaling pathwayGO:005086140.072
compound eye developmentGO:004874910.071
cellular protein catabolic processGO:00442571550.071
carbohydrate derivative biosynthetic processGO:19011371830.071
wnt signaling pathwayGO:00160551880.070
positive regulation of cytosolic calcium ion concentrationGO:0007204650.070
branching morphogenesis of an epithelial tubeGO:00487541590.070
activation of innate immune responseGO:0002218560.069
inflammatory responseGO:00069542440.069
cellular response to lipidGO:00713961450.069
gliogenesisGO:00420631410.069
cellular carbohydrate metabolic processGO:00442621190.068
mammary gland morphogenesisGO:0060443540.068
positive regulation of apoptotic signaling pathwayGO:2001235950.068
carbohydrate metabolic processGO:00059752300.068
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.067
regulation of synaptic growth at neuromuscular junctionGO:000858240.067
regulation of protein serine threonine kinase activityGO:00719001570.067
regulation of podosome assemblyGO:007180130.067
signal transduction in absence of ligandGO:0038034550.067
regulation of organelle assemblyGO:1902115190.067
regulation of map kinase activityGO:00434051200.065
osteoclast differentiationGO:0030316620.065
regulation of vesicle mediated transportGO:00606271390.065
camera type eye developmentGO:00430102660.064
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.064
cellular chemical homeostasisGO:00550822150.064
hemostasisGO:0007599780.063
mammary gland epithelial cell proliferationGO:0033598240.063
monosaccharide metabolic processGO:00059961060.063
cellular response to dna damage stimulusGO:00069742070.063
regulation of fibroblast migrationGO:0010762120.062
mitotic cell cycle processGO:19030471590.062
regulation of actin filament lengthGO:0030832450.062
vascular endothelial growth factor receptor signaling pathwayGO:0048010240.062
cytosolic calcium ion transportGO:0060401480.061
regulation of endocytosisGO:0030100690.061
alpha beta t cell activationGO:0046631910.060
positive regulation of epithelial cell proliferationGO:0050679680.060
b cell homeostasisGO:0001782340.060
regulation of mast cell activationGO:0033003210.060
protein modification by small protein conjugationGO:00324461870.060
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.059
regulation of protein targetingGO:1903533610.059
microtubule based processGO:00070172360.059
b cell apoptotic processGO:0001783190.059
stem cell differentiationGO:00488632680.059
leukocyte proliferationGO:00706611720.058
platelet aggregationGO:0070527200.058
leukocyte differentiationGO:00025213420.057
positive regulation of protein catabolic processGO:0045732600.057
coagulationGO:0050817780.057
positive regulation of neuron differentiationGO:00456661410.057
regulation of intracellular transportGO:00323861590.057
regulation of protein catabolic processGO:00421761080.056
positive regulation of dendritic cell apoptotic processGO:200067030.056
regulation of lamellipodium organizationGO:190274350.056
urogenital system developmentGO:00016552610.056
protein processingGO:00164851630.055
regulation of leukocyte differentiationGO:19021051590.055
reactive oxygen species metabolic processGO:0072593840.055
response to retinoic acidGO:0032526560.054
neurotrophin signaling pathwayGO:0038179120.054
extracellular structure organizationGO:00430621480.053
regulation of cell shapeGO:0008360390.053
regulation of lymphocyte activationGO:00512492400.053
regulation of protein kinase activityGO:00458592320.053
negative regulation of erk1 and erk2 cascadeGO:0070373210.053
t cell selectionGO:0045058340.052
divalent inorganic cation transportGO:00725111780.052
cell adhesion mediated by integrinGO:0033627180.052
regulation of metal ion transportGO:00109591060.052
tyrosine phosphorylation of stat5 proteinGO:004250690.051
regulation of protein processingGO:0070613960.051
mitotic cell cycleGO:00002781950.051
positive t cell selectionGO:0043368230.051
regulation of mitochondrial membrane potentialGO:0051881170.050
jnk cascadeGO:0007254720.050
negative regulation of protein maturationGO:1903318790.050
positive regulation of organelle organizationGO:00106381280.050
substrate dependent cell migration cell extensionGO:000693040.050
oocyte developmentGO:0048599330.049
regulation of reactive oxygen species metabolic processGO:2000377400.049
stem cell proliferationGO:00720891170.049
lymphocyte proliferationGO:00466511640.049
divalent metal ion transportGO:00708381720.049
immune response activating cell surface receptor signaling pathwayGO:0002429720.049
thymus developmentGO:0048538410.049
response to peptideGO:19016521360.049
Human
rac protein signal transductionGO:0016601130.048
regulation of calcium ion transportGO:0051924690.048
negative regulation of proteolysisGO:0045861740.048
filtration diaphragm assemblyGO:003605810.047
regulation of inositol phosphate biosynthetic processGO:001091930.047
positive regulation of insulin receptor signaling pathwayGO:004662840.047
epithelium migrationGO:0090132630.047
mesenchyme developmentGO:00604851520.047
regulation of phosphatidylinositol 3 kinase activityGO:0043551140.047
regulation of wnt signaling pathwayGO:00301111230.047
response to organic cyclic compoundGO:00140701980.046
regulation of body fluid levelsGO:00508781620.046
response to ischemiaGO:0002931140.046
b cell activationGO:00421131610.046
regulation of peptidyl serine phosphorylationGO:0033135390.045
regulation of jak stat cascadeGO:0046425340.045
protein maturationGO:00516041760.045
regulation of engulfment of apoptotic cellGO:190107420.045
learningGO:0007612980.045
positive regulation of exocytosisGO:0045921200.045
anatomical structure homeostasisGO:00602491450.045
regulation of osteoblast proliferationGO:0033688150.044
positive regulation of wnt signaling pathwayGO:0030177450.044
intracellular protein transportGO:00068862040.044
t cell differentiation in thymusGO:0033077770.044
epithelial cell developmentGO:00020641590.044
Fly
organic hydroxy compound metabolic processGO:19016152030.044
cytokinesisGO:0000910170.044
cellular response to organic cyclic compoundGO:0071407870.044
epidermal growth factor receptor signaling pathwayGO:0007173280.044
negative regulation of hormone biosynthetic processGO:003235340.043
tolerance induction to self antigenGO:000251340.043
symbiosis encompassing mutualism through parasitismGO:0044403830.043
innate immune responseGO:00450871570.043
positive regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001241100.043
radial glia guided migration of purkinje cellGO:002194260.043
regulation of neuron differentiationGO:00456642810.043
b cell differentiationGO:0030183780.042
regulation of mast cell degranulationGO:0043304160.042
pigment cell differentiationGO:0050931270.042
exocytosisGO:00068871210.042
regulation of epithelial cell migrationGO:0010632350.042
synaptic transmissionGO:00072683290.042
wound healingGO:00420601570.041
epithelial cell migrationGO:0010631630.041
myeloid cell homeostasisGO:00022621140.041
organonitrogen compound biosynthetic processGO:19015661920.041
negative regulation of phagocytosisGO:005076540.041
membrane invaginationGO:0010324170.041
neuron migrationGO:00017641220.040
erbb signaling pathwayGO:0038127320.040
signal transduction by p53 class mediatorGO:0072331510.040
regulation of actin filament polymerizationGO:0030833380.040
positive regulation of podosome assemblyGO:007180330.040
endothelial cell migrationGO:0043542440.040
regulation of glucose metabolic processGO:0010906600.039
regulation of ion transportGO:00432692150.039
positive regulation of phospholipase activityGO:001051830.039
regulation of pigment cell differentiationGO:005093270.038
columnar cuboidal epithelial cell differentiationGO:0002065820.038
Fly
negative regulation of immune system processGO:00026832090.038
leukocyte activation involved in immune responseGO:00023661260.038
insulin receptor signaling pathwayGO:0008286490.038
spermatid differentiationGO:00485151150.038
response to inorganic substanceGO:0010035960.038
cellular ion homeostasisGO:00068731650.038
ossificationGO:00015032160.037

Pxn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.172
musculoskeletal system diseaseDOID:1700.172
muscular diseaseDOID:008000000.139
myopathyDOID:42300.097
muscle tissue diseaseDOID:6600.097
immune system diseaseDOID:291400.038