| establishment of melanosome localization | GO:0032401 | 11 | 0.341 | |
| melanosome organization | GO:0032438 | 8 | 0.246 | Human |
| pigmentation | GO:0043473 | 71 | 0.238 | Human |
| pigment granule localization | GO:0051875 | 13 | 0.222 | |
| melanosome transport | GO:0032402 | 11 | 0.195 | |
| short chain fatty acid metabolic process | GO:0046459 | 6 | 0.189 | |
| pigment biosynthetic process | GO:0046148 | 26 | 0.171 | |
| melanin biosynthetic process | GO:0042438 | 10 | 0.122 | |
| secondary metabolite biosynthetic process | GO:0044550 | 11 | 0.114 | |
| melanosome localization | GO:0032400 | 12 | 0.098 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.090 | |
| ketone body metabolic process | GO:1902224 | 3 | 0.088 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.084 | |
| establishment of pigment granule localization | GO:0051905 | 12 | 0.079 | |
| pigment metabolic process | GO:0042440 | 32 | 0.078 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.076 | |
| phenol containing compound biosynthetic process | GO:0046189 | 21 | 0.073 | |
| transmembrane transport | GO:0055085 | 412 | 0.070 | |
| cellular pigmentation | GO:0033059 | 20 | 0.068 | Human |
| melanocyte differentiation | GO:0030318 | 25 | 0.065 | |
| developmental pigmentation | GO:0048066 | 40 | 0.062 | Human |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.061 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.060 | |
| amino acid transmembrane transport | GO:0003333 | 37 | 0.060 | |
| tyrosine metabolic process | GO:0006570 | 4 | 0.059 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.059 | |
| pigment cell differentiation | GO:0050931 | 27 | 0.058 | Human |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.057 | |
| pigment accumulation | GO:0043476 | 1 | 0.057 | Human |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.056 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.055 | |
| monocarboxylic acid metabolic process | GO:0032787 | 191 | 0.054 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.050 | |
| regulation of natural killer cell activation | GO:0032814 | 22 | 0.049 | |
| alpha amino acid metabolic process | GO:1901605 | 59 | 0.047 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.047 | |
| regulation of body fluid levels | GO:0050878 | 162 | 0.047 | |
| pigment granule transport | GO:0051904 | 12 | 0.046 | |
| secretory granule organization | GO:0033363 | 20 | 0.044 | Rat |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.044 | |
| vesicle organization | GO:0016050 | 60 | 0.043 | Human Rat |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.042 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.042 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.041 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.040 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.040 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.040 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.040 | |
| organic acid transport | GO:0015849 | 101 | 0.040 | |
| cellular homeostasis | GO:0019725 | 240 | 0.039 | Human |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.039 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.039 | |
| early endosome to late endosome transport | GO:0045022 | 2 | 0.038 | |
| secretion of lysosomal enzymes | GO:0033299 | 6 | 0.038 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.038 | |
| secondary metabolic process | GO:0019748 | 18 | 0.037 | |
| cation transport | GO:0006812 | 399 | 0.037 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.037 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.037 | |
| pigment granule organization | GO:0048753 | 9 | 0.037 | Human |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.037 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.036 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.036 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.036 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.035 | |
| fatty acid metabolic process | GO:0006631 | 121 | 0.034 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.034 | |
| melanin metabolic process | GO:0006582 | 12 | 0.034 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.034 | |
| amino acid transport | GO:0006865 | 61 | 0.034 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.033 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.033 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.032 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.032 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.032 | |
| regulation of nucleoside metabolic process | GO:0009118 | 130 | 0.031 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.031 | |
| organic anion transport | GO:0015711 | 137 | 0.031 | |
| natural killer cell activation | GO:0030101 | 44 | 0.030 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.030 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.030 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.030 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.030 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.029 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.029 | |
| phenol containing compound metabolic process | GO:0018958 | 60 | 0.029 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.028 | |
| anion transport | GO:0006820 | 177 | 0.028 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.028 | |
| organic hydroxy compound biosynthetic process | GO:1901617 | 77 | 0.028 | |
| regulation of reactive oxygen species biosynthetic process | GO:1903426 | 2 | 0.028 | |
| columnar cuboidal epithelial cell differentiation | GO:0002065 | 82 | 0.027 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.027 | |
| regulation of chloride transport | GO:2001225 | 2 | 0.027 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.026 | |
| thymus development | GO:0048538 | 41 | 0.026 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.025 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.025 | |
| carboxylic acid transport | GO:0046942 | 100 | 0.025 | |
| positive regulation of nervous system development | GO:0051962 | 221 | 0.025 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.025 | |
| camera type eye development | GO:0043010 | 266 | 0.024 | |
| gtp catabolic process | GO:0006184 | 143 | 0.024 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.023 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.023 | Human |
| divalent metal ion transport | GO:0070838 | 172 | 0.023 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.023 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.023 | |
| cell adhesion | GO:0007155 | 329 | 0.023 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.022 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.022 | |
| t cell activation | GO:0042110 | 289 | 0.022 | |
| forebrain development | GO:0030900 | 302 | 0.021 | |
| hormone secretion | GO:0046879 | 128 | 0.021 | |
| retina development in camera type eye | GO:0060041 | 119 | 0.021 | |
| cell activation involved in immune response | GO:0002263 | 126 | 0.021 | |
| regulation of ion transport | GO:0043269 | 215 | 0.021 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.021 | Human |
| gtp metabolic process | GO:0046039 | 144 | 0.021 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.021 | |
| vesicle localization | GO:0051648 | 86 | 0.021 | |
| cofactor metabolic process | GO:0051186 | 80 | 0.020 | |
| coagulation | GO:0050817 | 78 | 0.020 | |
| endomembrane system organization | GO:0010256 | 147 | 0.020 | Rat |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.020 | |
| amine metabolic process | GO:0009308 | 45 | 0.020 | |
| cation homeostasis | GO:0055080 | 212 | 0.020 | Human |
| compound eye development | GO:0048749 | 1 | 0.020 | |
| protein secretion | GO:0009306 | 111 | 0.019 | |
| skeletal system morphogenesis | GO:0048705 | 203 | 0.019 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.019 | Human |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.019 | |
| lysosome organization | GO:0007040 | 21 | 0.019 | Worm |
| skin development | GO:0043588 | 220 | 0.019 | |
| sulfur compound metabolic process | GO:0006790 | 100 | 0.019 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.019 | |
| epithelial cell development | GO:0002064 | 159 | 0.018 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.018 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.018 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.018 | |
| eye pigmentation | GO:0048069 | 3 | 0.018 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.017 | |
| blood circulation | GO:0008015 | 195 | 0.017 | |
| positive regulation of cellular ph reduction | GO:0032849 | 2 | 0.017 | |
| anion transmembrane transport | GO:0098656 | 71 | 0.017 | |
| carnitine transmembrane transport | GO:1902603 | 3 | 0.017 | |
| organelle localization | GO:0051640 | 179 | 0.017 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 40 | 0.017 | |
| response to acid chemical | GO:0001101 | 111 | 0.017 | |
| t cell mediated immunity | GO:0002456 | 50 | 0.017 | |
| epidermis development | GO:0008544 | 187 | 0.017 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.016 | |
| establishment of vesicle localization | GO:0051650 | 81 | 0.016 | |
| phospholipid metabolic process | GO:0006644 | 87 | 0.016 | |
| regulation of system process | GO:0044057 | 200 | 0.016 | |
| multicellular organismal homeostasis | GO:0048871 | 164 | 0.016 | |
| cell division | GO:0051301 | 120 | 0.016 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.016 | |
| sensory perception | GO:0007600 | 245 | 0.016 | |
| tissue remodeling | GO:0048771 | 102 | 0.016 | |
| aromatic amino acid family metabolic process | GO:0009072 | 9 | 0.016 | |
| innate immune response | GO:0045087 | 157 | 0.016 | |
| blood coagulation | GO:0007596 | 76 | 0.016 | |
| vacuole organization | GO:0007033 | 38 | 0.016 | Worm |
| regulation of protein processing | GO:0070613 | 96 | 0.016 | |
| lipid transport | GO:0006869 | 98 | 0.016 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.016 | |
| adult behavior | GO:0030534 | 135 | 0.015 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.015 | |
| locomotory behavior | GO:0007626 | 195 | 0.015 | |
| carnitine transport | GO:0015879 | 3 | 0.015 | |
| atp metabolic process | GO:0046034 | 75 | 0.015 | |
| negative regulation of nervous system development | GO:0051961 | 156 | 0.015 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.015 | |
| urogenital system development | GO:0001655 | 261 | 0.015 | |
| neural precursor cell proliferation | GO:0061351 | 121 | 0.015 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 91 | 0.015 | |
| mapk cascade | GO:0000165 | 281 | 0.015 | |
| mitochondrion organization | GO:0007005 | 134 | 0.015 | |
| positive regulation of lymphocyte activation | GO:0051251 | 140 | 0.015 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.015 | |
| cell killing | GO:0001906 | 67 | 0.014 | |
| lymphocyte differentiation | GO:0030098 | 242 | 0.014 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.014 | |
| hemostasis | GO:0007599 | 78 | 0.014 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.014 | |
| vitamin d3 metabolic process | GO:0070640 | 3 | 0.014 | |
| coenzyme metabolic process | GO:0006732 | 52 | 0.014 | |
| glucose homeostasis | GO:0042593 | 128 | 0.014 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.014 | |
| chemotaxis | GO:0006935 | 247 | 0.014 | |
| wound healing | GO:0042060 | 157 | 0.014 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 114 | 0.014 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.013 | |
| respiratory system development | GO:0060541 | 190 | 0.013 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.013 | |
| circulatory system process | GO:0003013 | 197 | 0.013 | |
| positive regulation of macroautophagy | GO:0016239 | 3 | 0.013 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 85 | 0.013 | |
| purinergic nucleotide receptor signaling pathway | GO:0035590 | 3 | 0.013 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.013 | |
| transepithelial chloride transport | GO:0030321 | 4 | 0.013 | |
| naphthalene containing compound metabolic process | GO:0090420 | 1 | 0.013 | |
| connective tissue development | GO:0061448 | 179 | 0.013 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.013 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.013 | |
| rho protein signal transduction | GO:0007266 | 32 | 0.013 | |
| cytokine production | GO:0001816 | 319 | 0.013 | |
| leukocyte mediated cytotoxicity | GO:0001909 | 62 | 0.013 | |
| positive regulation of interleukin 8 production | GO:0032757 | 2 | 0.013 | |
| calcium ion homeostasis | GO:0055074 | 127 | 0.012 | |
| regulation of homeostatic process | GO:0032844 | 182 | 0.012 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.012 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.012 | |
| membrane organization | GO:0061024 | 245 | 0.012 | Human |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.012 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.012 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.012 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.012 | |
| microtubule based process | GO:0007017 | 236 | 0.012 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.012 | |
| thrombin receptor signaling pathway | GO:0070493 | 2 | 0.012 | |
| interleukin 8 production | GO:0032637 | 4 | 0.012 | |
| protein maturation | GO:0051604 | 176 | 0.012 | |
| oligopeptide transmembrane transport | GO:0035672 | 4 | 0.012 | |
| reactive nitrogen species metabolic process | GO:2001057 | 0 | 0.012 | |
| peptide transport | GO:0015833 | 133 | 0.012 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.012 | |
| protein processing | GO:0016485 | 163 | 0.012 | |
| forebrain generation of neurons | GO:0021872 | 63 | 0.012 | |
| positive regulation of gtpase activity | GO:0043547 | 85 | 0.012 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.012 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.012 | |
| oxidation reduction process | GO:0055114 | 342 | 0.012 | |
| negative regulation of lymphocyte activation | GO:0051250 | 91 | 0.012 | |
| defecation | GO:0030421 | 1 | 0.012 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.012 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.011 | |
| acyl coa metabolic process | GO:0006637 | 19 | 0.011 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.011 | |
| innate immune response activating cell surface receptor signaling pathway | GO:0002220 | 4 | 0.011 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.011 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 114 | 0.011 | |
| peptidyl lysine modification | GO:0018205 | 77 | 0.011 | |
| cellular alcohol biosynthetic process | GO:0044108 | 3 | 0.011 | |
| dna metabolic process | GO:0006259 | 303 | 0.011 | |
| muscle tissue development | GO:0060537 | 308 | 0.011 | |
| retrograde transport endosome to golgi | GO:0042147 | 2 | 0.011 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.011 | |
| response to growth factor | GO:0070848 | 198 | 0.011 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 80 | 0.011 | |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002460 | 145 | 0.011 | |
| organophosphate biosynthetic process | GO:0090407 | 122 | 0.011 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.011 | |
| single organism cell adhesion | GO:0098602 | 156 | 0.011 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.011 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.011 | |
| cell fate commitment | GO:0045165 | 210 | 0.011 | |
| regulation of gtp catabolic process | GO:0033124 | 113 | 0.011 | |
| kidney development | GO:0001822 | 213 | 0.011 | |
| regulation of interleukin 8 production | GO:0032677 | 3 | 0.011 | |
| regulation of cell activation | GO:0050865 | 289 | 0.010 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.010 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 81 | 0.010 | |
| catecholamine metabolic process | GO:0006584 | 30 | 0.010 | |
| regulation of acute inflammatory response to non antigenic stimulus | GO:0002877 | 2 | 0.010 | |
| lung development | GO:0030324 | 164 | 0.010 | |
| positive regulation of natural killer cell activation | GO:0032816 | 15 | 0.010 | |
| regulation of ph | GO:0006885 | 26 | 0.010 | Human |
| response to inorganic substance | GO:0010035 | 96 | 0.010 | |
| negative regulation of cell development | GO:0010721 | 169 | 0.010 | |
| cellular alcohol metabolic process | GO:0044107 | 3 | 0.010 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.010 | |
| organic hydroxy compound transport | GO:0015850 | 93 | 0.010 | |
| alpha beta t cell activation | GO:0046631 | 91 | 0.010 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.010 | |
| lymphocyte activation involved in immune response | GO:0002285 | 93 | 0.010 | |
| protein localization to membrane | GO:0072657 | 108 | 0.010 | Human |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.010 | |
| natural killer cell degranulation | GO:0043320 | 3 | 0.010 | |
| positive regulation of cytokine production | GO:0001819 | 174 | 0.010 | |
| lymphocyte mediated immunity | GO:0002449 | 139 | 0.010 | |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.010 | |
| dopamine biosynthetic process | GO:0042416 | 6 | 0.010 | |
