Mus musculus

217 known processes

Rb1

retinoblastoma 1

(Aliases: Rb-1,Rb,pRb)

Rb1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of transcription involved in g1 s transition of mitotic cell cycleGO:007193011.000
negative regulation of cell cycleGO:00457861231.000
cellular response to dna damage stimulusGO:00069742071.000
regulation of somitogenesisGO:001480761.000
regionalizationGO:00030023371.000
glial cell apoptotic processGO:003434930.999
regulation of mitotic cell cycleGO:00073461260.999
regulation of cell cycleGO:00517262810.999
cellular response to antibioticGO:007123640.999
negative regulation of cell cycle phase transitionGO:1901988480.999
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573690.999
cell cycle arrestGO:0007050370.999
negative regulation of mitotic cell cycleGO:0045930580.998
regulation of transcription involved in g1 s transition of mitotic cell cycleGO:000008330.998
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.998
g1 s transition of mitotic cell cycleGO:0000082570.998
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.997
somite specificationGO:000175740.997
intrinsic apoptotic signaling pathwayGO:00971931320.997
negative regulation of blood vessel endothelial cell migrationGO:004353730.996
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.996
mitotic g1 dna damage checkpointGO:003157140.996
regulation of cell cycle g1 s phase transitionGO:1902806350.995
signal transduction by p53 class mediatorGO:0072331510.995
regulation of cell cycle phase transitionGO:1901987770.995
intra s dna damage checkpointGO:003157340.991
negative regulation of mitotic cell cycle phase transitionGO:1901991450.991
dna metabolic processGO:00062593030.991
negative regulation of protein serine threonine kinase activityGO:0071901490.989
mitotic cell cycle processGO:19030471590.989
negative regulation of glial cell proliferationGO:006025340.989
cell cycle g1 s phase transitionGO:0044843570.988
apoptotic signaling pathwayGO:00971903060.987
negative regulation of cell proliferationGO:00082852960.987
regulation of kinase activityGO:00435492490.987
Human
regulation of g1 s transition of mitotic cell cycleGO:2000045350.982
regulation of transferase activityGO:00513382630.978
Human
negative regulation of protein phosphorylationGO:00019331260.977
Human
regulation of protein kinase activityGO:00458592320.977
Human
regulation of mitotic cell cycle phase transitionGO:1901990730.977
negative regulation of immune system processGO:00026832090.973
somite developmentGO:0061053810.972
negative regulation of cell cycle processGO:0010948690.969
carbon catabolite activation of transcriptionGO:004599140.969
sensory perception of soundGO:0007605970.966
neural precursor cell proliferationGO:00613511210.966
t cell activationGO:00421102890.966
negative regulation of molecular functionGO:00440922580.963
Human
somitogenesisGO:0001756690.962
regulation of cell cycle processGO:00105641600.962
embryonic organ morphogenesisGO:00485622760.961
Worm
regulation of cell adhesionGO:00301551540.961
cell fate commitmentGO:00451652100.960
macroautophagyGO:0016236210.960
negative regulation of photoreceptor cell differentiationGO:004653340.958
auditory receptor cell fate determinationGO:004266830.956
cellular response to external stimulusGO:0071496880.955
dna damage response signal transduction by p53 class mediatorGO:0030330190.955
negative regulation of cellular protein metabolic processGO:00322692470.955
Human
mitotic cell cycleGO:00002781950.955
neuron apoptotic processGO:00514021420.950
regulation of auditory receptor cell differentiationGO:004560740.948
regulation of response to dna damage stimulusGO:2001020340.944
autophagyGO:0006914450.944
dendrite developmentGO:00163581150.943
chromatin modificationGO:00165681870.943
muscle tissue developmentGO:00605373080.942
regulation of cellular amino acid metabolic processGO:000652150.941
gland developmentGO:00487323300.939
negative regulation of protein metabolic processGO:00512482820.938
Human
signal transduction involved in dna integrity checkpointGO:007240130.936
positive regulation of protein modification processGO:00314012990.935
dna damage checkpointGO:0000077260.929
lymphocyte differentiationGO:00300982420.929
chromatin organizationGO:00063252060.925
covalent chromatin modificationGO:00165691630.924
cellular ketone metabolic processGO:0042180840.923
regulation of neuron apoptotic processGO:00435231220.919
blastocyst developmentGO:0001824800.919
cell type specific apoptotic processGO:00972852680.918
negative regulation of epithelial cell proliferationGO:0050680640.916
stem cell maintenanceGO:00198271300.915
positive regulation of apoptotic processGO:00430652170.912
myeloid cell differentiationGO:00300992330.912
negative regulation of phosphorylationGO:00423261660.909
Human
negative regulation of t cell proliferationGO:0042130380.907
regulation of microtubule polymerizationGO:003111370.904
midbrain hindbrain boundary morphogenesisGO:002155540.902
male gamete generationGO:00482322850.900
notch signaling pathwayGO:0007219710.898
negative regulation of g1 s transition of mitotic cell cycleGO:2000134180.897
cell adhesionGO:00071553290.891
mitotic cell cycle arrestGO:007185040.888
Worm
signal transduction involved in dna damage checkpointGO:007242230.887
regulation of cohesin localization to chromatinGO:007192210.887
Human
protein catabolic processGO:00301632210.885
Human
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.879
regulation of lymphocyte proliferationGO:00506701170.878
somatic stem cell maintenanceGO:0035019470.868
positive regulation of neuron deathGO:1901216280.867
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrestGO:000697730.867
regulation of embryonic developmentGO:0045995710.862
cellular amine metabolic processGO:0044106440.861
blood vessel morphogenesisGO:00485142850.856
forebrain developmentGO:00309003020.853
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.853
regulation of sequence specific dna binding transcription factor activityGO:00510901060.850
angiogenesisGO:00015252010.849
muscle cell differentiationGO:00426922610.849
liver developmentGO:0001889660.846
dna integrity checkpointGO:0031570280.840
response to nutrient levelsGO:00316671090.838
regulation of autophagyGO:0010506300.837
cellular amino acid metabolic processGO:00065201030.837
regulation of protein serine threonine kinase activityGO:00719001570.835
renal system developmentGO:00720012250.833
striated muscle tissue developmentGO:00147062930.831
organelle localizationGO:00516401790.822
Human
skeletal muscle organ developmentGO:00605381630.821
regulation of photoreceptor cell differentiationGO:004653240.819
negative regulation of growthGO:0045926990.819
negative regulation of neural precursor cell proliferationGO:2000178180.817
regulation of hydrolase activityGO:00513362460.816
metanephric nephron tubule formationGO:007228940.814
negative regulation of cell cycle g1 s phase transitionGO:1902807180.813
negative regulation of intracellular signal transductionGO:19025321670.810
negative regulation of auditory receptor cell differentiationGO:004560820.806
regulation of lymphocyte activationGO:00512492400.801
cell cycle checkpointGO:0000075470.794
cellular response to toxic substanceGO:009723770.793
signal transduction involved in mitotic dna damage checkpointGO:190240230.792
regulation of cardiac cell fate specificationGO:200004310.792
negative regulation of leukocyte proliferationGO:0070664460.791
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.788
positive regulation of rac protein signal transductionGO:003502210.788
negative regulation of pancreatic a cell differentiationGO:200022710.780
leukocyte differentiationGO:00025213420.779
heart morphogenesisGO:00030071780.777
cardiac chamber developmentGO:00032051080.775
extrinsic apoptotic signaling pathwayGO:00971911260.775
cellular response to oxidative stressGO:0034599760.775
regulation of epithelial cell proliferationGO:00506781410.774
negative regulation of leukocyte differentiationGO:1902106510.773
dna catabolic processGO:0006308190.773
dna biosynthetic processGO:0071897220.771
regulation of neuroblast proliferationGO:1902692270.771
response to light stimulusGO:00094161350.761
negative regulation of endothelial cell migrationGO:001059640.761
protein autophosphorylationGO:0046777610.761
cellular response to extracellular stimulusGO:0031668810.760
cardiac endothelial cell differentiationGO:000334840.759
regulation of neural precursor cell proliferationGO:2000177700.758
intracellular signal transduction involved in g1 dna damage checkpointGO:190240030.756
protein kinase b signalingGO:0043491740.756
positive regulation of epithelial cell proliferationGO:0050679680.749
response to radiationGO:00093141650.749
negative regulation of lymphocyte activationGO:0051250910.745
negative regulation of neurotransmitter secretionGO:004692950.745
sensory perception of mechanical stimulusGO:00509541070.742
positive regulation of apoptotic signaling pathwayGO:2001235950.741
signal transduction involved in cell cycle checkpointGO:007239530.740
inner ear receptor cell differentiationGO:0060113610.737
positive regulation of bmp signaling pathwayGO:0030513230.734
regulation of cellular amine metabolic processGO:0033238200.732
regulation of pro b cell differentiationGO:200097350.730
negative regulation of transferase activityGO:0051348850.730
Human
negative regulation of epidermal cell differentiationGO:004560570.728
cellular response to growth factor stimulusGO:00713631970.728
negative regulation of cell activationGO:00508661110.726
anoikisGO:004327660.718
regulation of intracellular transportGO:00323861590.716
regulation of bindingGO:00510981110.713
negative regulation of lymphocyte proliferationGO:0050672450.711
positive regulation of cellular amine metabolic processGO:003324050.709
negative regulation of oligodendrocyte differentiationGO:0048715110.704
branching morphogenesis of an epithelial tubeGO:00487541590.699
mitotic sister chromatid cohesionGO:000706410.698
Human
positive regulation of mitotic cell cycle phase transitionGO:1901992170.695
Human
neuroblast differentiationGO:001401620.694
auditory receptor cell differentiationGO:0042491370.694
neuroblast proliferationGO:0007405490.693
digestive system developmentGO:00551232000.690
signal transduction in absence of ligandGO:0038034550.690
regulation of endothelial cell proliferationGO:0001936230.686
spermatogenesisGO:00072832840.683
sprouting angiogenesisGO:0002040260.677
positive regulation of cell developmentGO:00107202370.677
response to ionizing radiationGO:0010212420.674
cellular response to abiotic stimulusGO:0071214560.673
leukocyte proliferationGO:00706611720.671
activation of cysteine type endopeptidase activityGO:0097202270.658
negative regulation of cell growthGO:0030308440.656
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631190.652
developmental programmed cell deathGO:0010623410.651
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediatorGO:0042771240.650
negative regulation of dna replicationGO:000815640.649
epithelial cell proliferation involved in prostate gland developmentGO:0060767110.647
regulation of leukocyte differentiationGO:19021051590.646
negative regulation of mechanoreceptor differentiationGO:004563230.646
positive regulation of transcription by galactoseGO:000041110.645
ascending aorta morphogenesisGO:003591030.645
neuron deathGO:00709971540.641
germ cell developmentGO:00072811850.641
response to oxygen levelsGO:0070482620.640
negative regulation of inner ear receptor cell differentiationGO:200098130.639
cell divisionGO:00513011200.638
mitotic cell cycle checkpointGO:0007093310.637
negative regulation of glial cell differentiationGO:0045686210.636
positive regulation of reactive oxygen species metabolic processGO:2000379110.634
spermatid differentiationGO:00485151150.634
developmental maturationGO:00217001930.633
keratinocyte differentiationGO:0030216480.632
dna replicationGO:0006260520.631
regulation of cell growthGO:0001558910.628
cell growthGO:00160491300.628
cation transportGO:00068123990.627
negative regulation of kinase activityGO:0033673810.624
Human
stomach neuroendocrine cell differentiationGO:006110220.623
segment specificationGO:0007379150.622
regulation of epidermal cell differentiationGO:0045604210.622
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.621
sperm individualizationGO:000729110.620
ear developmentGO:00435832000.618
cellular response to nutrient levelsGO:0031669640.617
cellular response to ionizing radiationGO:0071479110.608
pallium developmentGO:00215431200.603
positive regulation of myeloid cell differentiationGO:0045639430.602
negative regulation of epidermis developmentGO:004568390.602
regulation of protein kinase b signalingGO:0051896560.600
hair cell differentiationGO:0035315400.598
positive regulation of neuron apoptotic processGO:0043525250.598
stem cell proliferationGO:00720891170.596
epithelial tube morphogenesisGO:00605623030.595
digestive tract developmentGO:00485651900.595
positive regulation of bindingGO:0051099490.589
positive regulation of neuroblast proliferationGO:0002052190.589
regulation of t cell proliferationGO:0042129920.585
central nervous system neuron differentiationGO:00219531620.581
epithelial cell differentiation involved in prostate gland developmentGO:0060742130.581
pole plasm assemblyGO:000731520.575
stem cell differentiationGO:00488632680.571
positive regulation of protein phosphorylationGO:00019342420.571
neuroblast fate determinationGO:000740010.570
erythrocyte differentiationGO:0030218880.569
regulation of protein localizationGO:00328802310.567
Human
regulation of protein processingGO:0070613960.563
skeletal muscle cell differentiationGO:0035914660.562
negative regulation of protein processingGO:0010955790.560
outflow tract morphogenesisGO:0003151530.560
nuclear divisionGO:00002801580.559
Human
regulation of inner ear receptor cell differentiationGO:200098050.559
columnar cuboidal epithelial cell differentiationGO:0002065820.557
positive regulation of notch signaling pathwayGO:0045747180.557
regulation of leukocyte proliferationGO:00706631210.557
regulation of reactive oxygen species metabolic processGO:2000377400.555
regulation of oligodendrocyte differentiationGO:0048713230.555
cohesin localization to chromatinGO:007192110.551
Human
response to organonitrogen compoundGO:00102432460.550
embryonic epithelial tube formationGO:00018381300.543
positive regulation of osteoblast differentiationGO:0045669340.540
artery developmentGO:0060840530.538
negative regulation of lymphocyte differentiationGO:0045620320.537
proximal distal pattern formation involved in nephron developmentGO:007204750.535
stem cell fate specificationGO:004886630.533
regulation of myeloid cell differentiationGO:0045637960.532
macromolecule methylationGO:00434141200.529
positive regulation of mitotic sister chromatid separationGO:190197020.529
Human
axonogenesisGO:00074092740.519
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.518
cellular macromolecule catabolic processGO:00442652060.516
Human
positive regulation of cellular amino acid metabolic processGO:004576430.516
diencephalon developmentGO:0021536630.511
morphogenesis of a branching epitheliumGO:00611381930.509
regulation of neuron deathGO:19012141340.509
negative regulation of stomach neuroendocrine cell differentiationGO:006110610.508
protein methylationGO:0006479810.507
cellular homeostasisGO:00197252400.506
response to decreased oxygen levelsGO:0036293590.505
positive regulation of programmed cell deathGO:00430682180.505
segmentationGO:0035282930.504
kidney developmentGO:00018222130.499
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.497
response to extracellular stimulusGO:00099911270.495
regulation of dna replicationGO:0006275170.493
cardiac right ventricle formationGO:000321930.493
lateral inhibitionGO:004633110.491
negative regulation of immature t cell proliferationGO:003308730.490
positive regulation of insulin secretionGO:0032024260.490
extracellular matrix organizationGO:00301981470.490
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediatorGO:000697820.487
regulation of cellular ketone metabolic processGO:0010565660.485
cellular response to peptide hormone stimulusGO:0071375920.484
epithelial cell proliferationGO:00506731740.483
placenta blood vessel developmentGO:0060674310.481
regulation of cell substrate adhesionGO:0010810730.481
regulation of nucleocytoplasmic transportGO:0046822730.480
regulation of cellular response to stressGO:00801351590.480
signal transduction in response to dna damageGO:0042770210.477
cell maturationGO:00484691270.477
regulation of protein import into nucleus translocationGO:003315820.476
digestive tract morphogenesisGO:00485461470.475
Worm
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051220.473
t cell proliferationGO:00420981200.472
oocyte differentiationGO:0009994350.472
blood vessel lumenizationGO:007255420.472
microtubule based processGO:00070172360.469
Human
negative regulation of notch signaling pathwayGO:0045746140.469
positive regulation of proteolysisGO:0045862850.468
Human
neuron maturationGO:0042551290.466
negative regulation of phosphate metabolic processGO:00459361840.465
Human
hepaticobiliary system developmentGO:0061008670.465
myeloid leukocyte differentiationGO:00025731190.465
positive regulation of cell deathGO:00109422240.464
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100430.462
negative regulation of phosphatidylinositol 3 kinase activityGO:004355310.460
histone methylationGO:0016571710.454
carbohydrate homeostasisGO:00335001280.451
positive regulation of rap gtpase activityGO:003285430.447
positive regulation of lens epithelial cell proliferationGO:200111110.446
positive regulation of protein serine threonine kinase activityGO:00719021060.446
negative regulation of proteolysisGO:0045861740.445
signal transduction involved in mitotic cell cycle checkpointGO:007241330.434
positive regulation of mitotic cell cycleGO:0045931410.432
Human
peptidyl amino acid modificationGO:00181933360.427
negative regulation of protein maturationGO:1903318790.427
female gamete generationGO:0007292740.424
epithelial tube formationGO:00721751300.424
posttranscriptional regulation of gene expressionGO:00106081550.423
blastocyst growthGO:0001832230.422
cellular response to cytokine stimulusGO:00713451890.418
positive regulation of microtubule polymerizationGO:003111630.417
atrioventricular node developmentGO:000316230.417
positive regulation of ras protein signal transductionGO:0046579130.414
labyrinthine layer blood vessel developmentGO:0060716210.412
regulation of epithelial cell proliferation involved in prostate gland developmentGO:0060768100.412
signal transduction involved in mitotic g1 dna damage checkpointGO:007243130.409
nucleocytoplasmic transportGO:00069131390.408
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.408
lymphocyte proliferationGO:00466511640.406
pro b cell differentiationGO:0002328100.406
regulation of cell activationGO:00508652890.405
circadian rhythmGO:00076231140.404
morphogenesis of an endotheliumGO:000315920.404
b cell activationGO:00421131610.404
positive regulation of glial cell differentiationGO:0045687210.403
mapk cascadeGO:00001652810.402
photoreceptor cell morphogenesisGO:000859430.400
endocardial cushion to mesenchymal transition involved in heart valve formationGO:000319940.400
endodermal cell fate determinationGO:000749320.399
oocyte axis specificationGO:000730920.399
negative regulation of neuron deathGO:1901215980.397
mitotic sister chromatid separationGO:005130690.397
Human
negative regulation of b cell proliferationGO:0030889130.397
negative regulation of fibroblast migrationGO:001076420.394
positive regulation of kinase activityGO:00336741550.393
sister chromatid cohesionGO:0007062120.390
Human
regulation of androgen receptor signaling pathwayGO:006076530.390
positive regulation of transferase activityGO:00513471670.389
positive regulation of endothelial cell proliferationGO:0001938170.389
respiratory tube developmentGO:00303231670.387
response to uvGO:0009411440.381
negative regulation of synaptic vesicle exocytosisGO:200030130.378
response to hypoxiaGO:0001666580.375
blood vessel endothelial cell migrationGO:0043534230.374
epidermis developmentGO:00085441870.373
negative regulation of t cell activationGO:0050868650.370
negative regulation of neuron apoptotic processGO:0043524920.370
oogenesisGO:0048477560.366
skin developmentGO:00435882200.365
neural tube developmentGO:00219151600.365
ventricular septum morphogenesisGO:0060412270.364
regulation of protein stabilityGO:0031647520.363
regulation of endopeptidase activityGO:0052548890.363
regulation of cell sizeGO:0008361720.362
monocyte differentiationGO:003022490.358
protein maturationGO:00516041760.358
gliogenesisGO:00420631410.358
protein processingGO:00164851630.358
positive regulation of transcription by glucoseGO:004601630.353
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.350
regulation of sister chromatid cohesionGO:000706350.349
Human
intrahepatic bile duct developmentGO:003562220.349
membrane organizationGO:00610242450.348
regulation of neuron differentiationGO:00456642810.348
negative regulation of nervous system developmentGO:00519611560.347
sensory perceptionGO:00076002450.347
spermatid developmentGO:00072861080.346
positive regulation of histone methylationGO:0031062160.344
negative regulation of cell developmentGO:00107211690.343
dna catabolic process endonucleolyticGO:0000737150.343
gastrulationGO:00073691160.342
response to peptideGO:19016521360.341
positive regulation of autophagyGO:001050890.338
purine nucleoside metabolic processGO:00422782410.335
regulation of myeloid leukocyte differentiationGO:0002761580.335
purine nucleotide metabolic processGO:00061633020.335
response to x rayGO:0010165110.330
positive regulation of keratinocyte differentiationGO:004561830.330
positive regulation of cysteine type endopeptidase activityGO:2001056390.329
negative regulation of phosphorus metabolic processGO:00105631840.329
Human
mitochondrial dna repairGO:004350430.329
embryonic skeletal system developmentGO:00487061200.328
regulation of anoikisGO:200020920.328
megakaryocyte differentiationGO:0030219260.327
cardiac muscle tissue developmentGO:00487381300.326
cell fate determinationGO:0001709320.325
positive regulation of mitotic cell cycle embryonicGO:004597720.324
regulation of dna templated transcription in response to stressGO:004362090.324
regulation of histone methylationGO:0031060300.323
negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902042110.322
actin filament organizationGO:00070151130.322
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919270.318
regulation of cell morphogenesis involved in differentiationGO:00107691510.317
single organismal cell cell adhesionGO:00163371310.315
smoothened signaling pathwayGO:00072241050.314
stem cell developmentGO:00488642190.312
negative regulation of mesodermal cell fate specificationGO:004266230.311
histone modificationGO:00165701590.309
canonical wnt signaling pathwayGO:00600701300.309
forebrain radial glial cell differentiationGO:002186140.309
regulation of gliogenesisGO:0014013500.308
neural crest cell developmentGO:0014032480.307
cellular response to inorganic substanceGO:0071241370.306
modification dependent protein catabolic processGO:00199411330.305
Human
protein localization to nucleusGO:00345041210.304
regulation of canonical wnt signaling pathwayGO:0060828820.302
sensory organ boundary specificationGO:000805210.302
ras protein signal transductionGO:0007265770.302
Human
microtubule polymerization or depolymerizationGO:0031109260.301
regulation of cysteine type endopeptidase activityGO:2000116650.301
establishment of vesicle localizationGO:0051650810.300
response to endoplasmic reticulum stressGO:0034976530.299
positive regulation of wound healingGO:0090303170.296
cellular response to organonitrogen compoundGO:00714171450.296
regulation of cardiac muscle tissue growthGO:0055021260.296
negative regulation of macroautophagyGO:001624250.296
compound eye developmentGO:004874910.291
regulation of notch signaling pathwayGO:0008593350.291
endodermal cell fate specificationGO:000171440.290
dna endoreduplicationGO:004202340.288
positive regulation of histone modificationGO:0031058280.287
microtubule polymerizationGO:0046785120.287
negative regulation of astrocyte differentiationGO:0048712100.287
neural tube closureGO:0001843900.283
telencephalon developmentGO:00215371860.282
heterocycle catabolic processGO:00467002800.282
peripheral nervous system neuron axonogenesisGO:004893630.281
myeloid cell homeostasisGO:00022621140.280
negative regulation of anoikisGO:200081120.278
zymogen activationGO:0031638410.276
negative regulation of cellular catabolic processGO:0031330470.276
ureteric bud developmentGO:0001657940.275
schwann cell proliferationGO:001401020.274
fat cell differentiationGO:00454441600.274
cellular response to transforming growth factor beta stimulusGO:0071560880.273
endothelial tube morphogenesisGO:006115420.272
positive regulation of transcription from rna polymerase ii promoter by glucoseGO:000043230.271
positive regulation of keratinocyte proliferationGO:001083840.271
positive regulation of myeloid cell apoptotic processGO:003303440.271
negative regulation of tor signalingGO:0032007130.270
regulation of timing of neuron differentiationGO:006016450.269
negative regulation of lipid kinase activityGO:009021910.268
protein localization to chromatinGO:007116830.268
Human
somite rostral caudal axis specificationGO:0032525130.266
regulation of exocytosisGO:0017157610.265
negative regulation of dendritic spine morphogenesisGO:006100230.265
neuron projection guidanceGO:00974851410.262
cellular response to drugGO:0035690150.262
cellular response to metal ionGO:0071248310.261
mechanoreceptor differentiationGO:0042490670.260
protein alkylationGO:0008213810.259
protein targetingGO:00066051430.257
regulation of protein maturationGO:1903317960.255
locomotory behaviorGO:00076261950.254
ascending aorta developmentGO:003590530.254
positive regulation of apoptotic process involved in mammary gland involutionGO:006005840.254
extracellular structure organizationGO:00430621480.253

Rb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.998
Human
cancerDOID:16200.980
Human
organ system cancerDOID:005068600.980
Human
endocrine gland cancerDOID:17000.951
thoracic cancerDOID:509300.636
pancreatic cancerDOID:179300.605
disease of metabolismDOID:001466700.599
immune system cancerDOID:006008300.556
hematologic cancerDOID:253100.556
sensory system diseaseDOID:005015500.397
disease of anatomical entityDOID:700.397
nervous system diseaseDOID:86300.397
respiratory system cancerDOID:005061500.366
Human
large intestine cancerDOID:567200.266
colon cancerDOID:21900.266
gastrointestinal system cancerDOID:311900.266
intestinal cancerDOID:1015500.266
colorectal cancerDOID:925600.266