Mus musculus

170 known processes

Ripk1

receptor (TNFRSF)-interacting serine-threonine kinase 1

(Aliases: Rip1,D330015H01Rik,Rinp,RIP)

Ripk1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of defense responseGO:00313472330.926
Mouse
necroptotic processGO:0070266210.886
lymphocyte mediated immunityGO:00024491390.879
Mouse
lymphocyte homeostasisGO:0002260640.879
Mouse
i kappab kinase nf kappab signalingGO:0007249850.865
activation of immune responseGO:00022531380.861
Mouse
activation induced cell death of t cellsGO:0006924100.857
Mouse
cytokine mediated signaling pathwayGO:00192211150.834
Mouse
cytokine productionGO:00018163190.834
Human Mouse
positive regulation of cell activationGO:00508671580.800
Mouse
defense response to other organismGO:00985421970.776
Mouse
regulation of cell activationGO:00508652890.764
Mouse
t cell proliferationGO:00420981200.755
Mouse
necroptotic signaling pathwayGO:009752730.742
regulation of leukocyte proliferationGO:00706631210.735
Mouse
negative regulation of necroptotic processGO:006054690.724
response to lipopolysaccharideGO:00324961280.721
Mouse
t cell apoptotic processGO:0070231390.713
nik nf kappab signalingGO:0038061140.699
Mouse
regulation of sequence specific dna binding transcription factor activityGO:00510901060.698
ripoptosome assembly involved in necroptotic processGO:190102660.668
regulation of necroptotic processGO:0060544100.667
Human Mouse
regulation of interleukin 6 productionGO:0032675550.666
Mouse
immune effector processGO:00022523210.661
Mouse
positive regulation of apoptotic processGO:00430652170.660
response to interleukin 1GO:0070555110.653
Mouse
positive regulation of cytokine productionGO:00018191740.627
Human Mouse
regulation of innate immune responseGO:0045088910.610
Mouse
cytoplasmic pattern recognition receptor signaling pathwayGO:0002753100.605
Mouse
lymphocyte apoptotic processGO:0070227540.601
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.588
negative regulation of cell activationGO:00508661110.583
adaptive immune responseGO:00022501550.536
Mouse
regulation of apoptotic signaling pathwayGO:20012331970.534
lymphocyte proliferationGO:00466511640.526
Mouse
response to molecule of bacterial originGO:00022371430.516
Mouse
negative regulation of necrotic cell deathGO:0060547110.515
immune response activating signal transductionGO:00027571160.494
Mouse
regulation of cytokine productionGO:00018172660.492
Human Mouse
activation of nf kappab inducing kinase activityGO:000725040.491
t cell activationGO:00421102890.468
Mouse
immune response regulating signaling pathwayGO:00027641250.468
Mouse
protein polyubiquitinationGO:0000209330.459
regulation of t cell proliferationGO:0042129920.451
Mouse
t cell homeostasisGO:0043029350.444
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.442
Mouse
cellular response to lipidGO:00713961450.436
Mouse
leukocyte proliferationGO:00706611720.424
Mouse
positive regulation of immune effector processGO:00026991070.423
Mouse
extrinsic apoptotic signaling pathwayGO:00971911260.421
jnk cascadeGO:0007254720.398
protein ubiquitinationGO:00165671710.391
positive regulation of leukocyte differentiationGO:1902107860.377
Human Mouse
cellular response to molecule of bacterial originGO:0071219830.372
Mouse
protein modification by small protein conjugation or removalGO:00706472070.365
lipopolysaccharide mediated signaling pathwayGO:0031663250.361
Mouse
spleen developmentGO:0048536390.349
Mouse
nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042750.318
Mouse
t cell activation involved in immune responseGO:0002286430.318
Mouse
stress activated mapk cascadeGO:0051403800.318
negative regulation of nf kappab transcription factor activityGO:0032088150.317
regulation of mapk cascadeGO:00434082480.307
cellular response to biotic stimulusGO:0071216920.306
Mouse
cd8 positive alpha beta cytotoxic t cell extravasationGO:003569820.299
Mouse
positive regulation of programmed cell deathGO:00430682180.297
apoptotic signaling pathwayGO:00971903060.294
type i interferon productionGO:0032606290.287
response to tumor necrosis factorGO:0034612260.283
Human
cellular protein catabolic processGO:00442571550.272
Human
macromolecule catabolic processGO:00090572810.271
Human
negative regulation of defense responseGO:0031348770.269
positive regulation of cell deathGO:00109422240.269
protein catabolic processGO:00301632210.266
Human
myeloid leukocyte activationGO:0002274830.260
regulation of jnk cascadeGO:0046328620.255
regulation of lymphocyte activationGO:00512492400.253
Mouse
myeloid cell differentiationGO:00300992330.253
Human
stress activated protein kinase signaling cascadeGO:0031098810.245
cellular response to cytokine stimulusGO:00713451890.242
Human Mouse
negative regulation of lymphocyte activationGO:0051250910.240
regulation of intracellular transportGO:00323861590.235
positive regulation of apoptotic signaling pathwayGO:2001235950.235
regulation of necrotic cell deathGO:0010939130.233
Human Mouse
negative regulation of immune system processGO:00026832090.226
regulation of leukocyte mediated immunityGO:00027031040.219
Mouse
lymphocyte differentiationGO:00300982420.219
Mouse
negative regulation of t cell activationGO:0050868650.215
cell killingGO:0001906670.213
Mouse
necrotic cell deathGO:0070265300.195
protein modification by small protein removalGO:0070646210.193
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.193
Mouse
positive regulation of production of molecular mediator of immune responseGO:0002702450.190
positive regulation of lymphocyte activationGO:00512511400.186
Mouse
positive regulation of protein modification processGO:00314012990.186
Human Mouse
t cell mediated immunityGO:0002456500.183
Mouse
regulation of alpha beta t cell activationGO:0046634530.177
Mouse
cd8 positive alpha beta t cell extravasationGO:003569730.172
Mouse
cellular ketone metabolic processGO:0042180840.170
interleukin 5 secretionGO:007260320.169
interleukin 1 mediated signaling pathwayGO:007049840.167
leukocyte apoptotic processGO:0071887710.165
cellular response to lipopolysaccharideGO:0071222770.165
Mouse
t cell differentiation in thymusGO:0033077770.163
Mouse
regulation of cellular catabolic processGO:00313292420.162
regulation of t cell mediated immunityGO:0002709340.160
Mouse
positive regulation of interleukin 8 productionGO:003275720.160
Human
immune response regulating cell surface receptor signaling pathwayGO:0002768800.159
Mouse
interleukin 2 productionGO:0032623330.158
Mouse
positive regulation of defense responseGO:00313491240.156
Mouse
nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043160.152
Mouse
leukocyte mediated immunityGO:00024431740.151
Mouse
regulation of interleukin 2 productionGO:0032663280.150
Mouse
regulation of protein secretionGO:0050708820.148
programmed necrotic cell deathGO:0097300280.148
positive regulation of leukocyte proliferationGO:0070665730.147
Mouse
regulation of cd8 positive alpha beta cytotoxic t cell extravasationGO:200045220.146
Mouse
cell type specific apoptotic processGO:00972852680.145
leukocyte differentiationGO:00025213420.144
Human Mouse
cd4 positive alpha beta t cell activationGO:0035710450.143
Mouse
regulation of hepatocyte proliferationGO:200034560.142
amine metabolic processGO:0009308450.141
positive regulation of interferon gamma productionGO:0032729390.140
Mouse
regulation of protein localizationGO:00328802310.138
positive regulation of cellular protein catabolic processGO:1903364340.137
interleukin 8 productionGO:003263740.136
Human
regulation of lymphocyte mediated immunityGO:0002706840.136
Mouse
neuron deathGO:00709971540.135
regulation of cellular amino acid metabolic processGO:000652150.134
regulation of inflammatory responseGO:00507271470.134
negative regulation of interleukin 6 productionGO:0032715170.132
alpha beta t cell activationGO:0046631910.132
Mouse
t cell mediated cytotoxicityGO:0001913260.130
Mouse
regulation of interleukin 10 secretionGO:200117940.129
regulation of lymphocyte apoptotic processGO:0070228410.129
Mouse
homeostasis of number of cellsGO:00488722100.128
Mouse
protein modification by small protein conjugationGO:00324461870.127
negative regulation of interleukin 2 productionGO:003270380.125
lymph node developmentGO:0048535180.125
Mouse
cellular macromolecule catabolic processGO:00442652060.120
Human
regulation of adaptive immune responseGO:0002819900.118
Mouse
activation of innate immune responseGO:0002218560.116
Mouse
alpha beta t cell differentiation involved in immune responseGO:0002293300.116
Mouse
negative regulation of ripoptosome assembly involved in necroptotic processGO:190244330.115
negative regulation of molecular functionGO:00440922580.115
regulation of transferase activityGO:00513382630.113
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.113
Mouse
positive regulation of cellular catabolic processGO:00313311480.113
cytokine metabolic processGO:0042107710.112
cellular response to growth factor stimulusGO:00713631970.111
positive regulation of jnk cascadeGO:0046330460.108
regulation of stress activated mapk cascadeGO:0032872690.107
positive regulation of lymphocyte mediated immunityGO:0002708620.107
regulation of cellular protein catabolic processGO:1903362610.106
lipid localizationGO:00108761260.104
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.103
Mouse
t helper cell differentiationGO:0042093280.101
Mouse
ribose phosphate metabolic processGO:00196932910.101
tumor necrosis factor mediated signaling pathwayGO:0033209130.100
innate immune response activating signal transductionGO:0002758500.099
Mouse
skin developmentGO:00435882200.099
regulation of response to woundingGO:19030341890.099
positive regulation of transferase activityGO:00513471670.098
regulation of cellular ketone metabolic processGO:0010565660.097
negative regulation of b cell activationGO:0050869270.097
positive regulation of lymphocyte proliferationGO:0050671700.096
Mouse
protein oligomerizationGO:0051259670.096
Human
intrinsic apoptotic signaling pathwayGO:00971931320.095
Mouse
regulation of leukocyte differentiationGO:19021051590.094
Human Mouse
negative regulation of lymphocyte proliferationGO:0050672450.094
negative regulation of lipopolysaccharide mediated signaling pathwayGO:003166530.094
regulation of cell motilityGO:20001452360.090
Mouse
regulation of cytokine biosynthetic processGO:0042035590.090
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.090
toll like receptor 3 signaling pathwayGO:003413840.090
myeloid leukocyte differentiationGO:00025731190.089
Human
regulation of nucleotide binding oligomerization domain containing signaling pathwayGO:007042430.089
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.088
type i interferon signaling pathwayGO:0060337100.088
positive regulation of cellular amine metabolic processGO:003324050.087
positive regulation of leukocyte mediated immunityGO:0002705700.087
regulation of tight junction assemblyGO:200081020.087
regulation of activated t cell proliferationGO:0046006160.086
Mouse
positive regulation of protein catabolic processGO:0045732600.086
regulation of nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042830.084
regulation of secretion by cellGO:19035302490.084
regulation of hydrolase activityGO:00513362460.084
antimicrobial peptide productionGO:000277520.083
regulation of protein kinase activityGO:00458592320.083
b 1 b cell homeostasisGO:000192240.083
regulation of protein transportGO:00512231630.082
regulation of cd8 positive alpha beta t cell extravasationGO:200044930.082
Mouse
interleukin 10 secretionGO:007260840.081
regulation of proteolysisGO:00301621640.081
negative regulation of cytokine productionGO:0001818840.080
lymphocyte migrationGO:0072676260.079
Mouse
regulation of ion transportGO:00432692150.078
Human
regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902041220.078
posttranscriptional regulation of gene expressionGO:00106081550.078
negative regulation of response to woundingGO:1903035770.078
regulation of alpha beta t cell proliferationGO:0046640180.078
Mouse
cd4 positive alpha beta t cell differentiationGO:0043367410.077
Mouse
response to endoplasmic reticulum stressGO:0034976530.075
regulation of leukocyte mediated cytotoxicityGO:0001910380.075
Mouse
regulation of interleukin 8 productionGO:003267730.074
Human
positive regulation of antimicrobial peptide productionGO:000222510.074
regulation of secretionGO:00510462740.074
positive regulation of interleukin 6 productionGO:0032755370.073
Mouse
immunoglobulin productionGO:0002377730.073
response to oxidative stressGO:00069791230.073
leukocyte homeostasisGO:0001776790.073
Mouse
protein localization to organelleGO:00333651850.073
production of molecular mediator of immune responseGO:00024401030.071
positive regulation of response to cytokine stimulusGO:0060760110.071
Mouse
cellular nitrogen compound catabolic processGO:00442702800.070
regulation of defense response to virusGO:0050688180.069
membrane organizationGO:00610242450.069
maintenance of locationGO:0051235890.068
interferon gamma productionGO:0032609670.067
Mouse
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.067
positive regulation of protein oligomerizationGO:003246140.067
regulation of cellular response to stressGO:00801351590.067
regulation of endocytosisGO:0030100690.065
regulation of response to cytokine stimulusGO:0060759230.065
Mouse
cellular amino acid metabolic processGO:00065201030.065
positive regulation of myeloid leukocyte differentiationGO:0002763260.064
Human
cofactor metabolic processGO:0051186800.064
notch signaling pathwayGO:0007219710.064
mapk cascadeGO:00001652810.064
negative regulation of multi organism processGO:0043901680.063
protein deubiquitinationGO:0016579190.062
nucleotide binding domain leucine rich repeat containing receptor signaling pathwayGO:003587260.062
Mouse
negative regulation of intracellular signal transductionGO:19025321670.061
Human
regulation of homeostatic processGO:00328441820.060
Mouse
negative regulation of inflammatory responseGO:0050728610.060
negative regulation of leukocyte proliferationGO:0070664460.059
cellular response to external stimulusGO:0071496880.059
regulation of t cell activationGO:00508631700.058
Mouse
regulation of actin filament based processGO:0032970990.058
cellular amine metabolic processGO:0044106440.058
regulation of antibacterial peptide biosynthetic processGO:000280810.058
anion transportGO:00068201770.057
Human
purine nucleotide metabolic processGO:00061633020.057
negative regulation of alpha beta t cell activationGO:0046636180.057
negative regulation of interleukin 1 beta productionGO:003269150.056
glycosyl compound metabolic processGO:19016572460.056
negative regulation of cell proliferationGO:00082852960.056
glial cell apoptotic processGO:003434930.056
purine ribonucleoside metabolic processGO:00461282410.055
regulation of b cell activationGO:0050864810.054
response to organonitrogen compoundGO:00102432460.054
Mouse
protein k48 linked ubiquitinationGO:007093670.053
inflammatory responseGO:00069542440.053
response to reactive oxygen speciesGO:0000302560.053
defense response to virusGO:0051607680.052
regulation of organelle organizationGO:00330432890.052
positive regulation of protein kinase activityGO:00458601440.052
negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902042110.052
antigen receptor mediated signaling pathwayGO:0050851640.051
Mouse
positive regulation of hydrolase activityGO:00513451480.051
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573690.051
protein homotrimerizationGO:007020740.051
ossificationGO:00015032160.050
protein maturationGO:00516041760.050
dna metabolic processGO:00062593030.050
protein localization to vacuoleGO:007266540.049
t cell differentiation involved in immune responseGO:0002292300.049
Mouse
regulation of cellular component biogenesisGO:00440871810.049
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.049
positive regulation of interferon alpha productionGO:003272740.049
regulation of lymphocyte proliferationGO:00506701170.048
Mouse
positive regulation of lipopolysaccharide mediated signaling pathwayGO:003166650.048
wound healingGO:00420601570.048
nucleoside triphosphate metabolic processGO:00091412300.048
type i interferon biosynthetic processGO:004535190.047
aromatic compound catabolic processGO:00194392860.047
neural tube formationGO:00018411080.047
regulation of establishment of protein localizationGO:00702011810.046
regulation of protein oligomerizationGO:003245940.046
cellular response to abiotic stimulusGO:0071214560.046
proteolysis involved in cellular protein catabolic processGO:00516031470.046
cellular response to steroid hormone stimulusGO:0071383330.046
b cell homeostasisGO:0001782340.045
osteoclast differentiationGO:0030316620.045
positive regulation of alpha beta t cell differentiationGO:0046638280.044
Mouse
cellular protein complex assemblyGO:00436231160.044
regulation of reactive oxygen species metabolic processGO:2000377400.044
positive regulation of kinase activityGO:00336741550.044
ion transmembrane transportGO:00342203610.044
Human
neuron apoptotic processGO:00514021420.044
positive regulation of t cell mediated immunityGO:0002711240.043
positive regulation of secretionGO:00510471300.043
regulation of lymphocyte differentiationGO:00456191070.042
Mouse
cellular lipid metabolic processGO:00442553230.042
regulation of cytokine secretionGO:0050707610.042
heterocycle catabolic processGO:00467002800.042
regulation of cytokine secretion involved in immune responseGO:000273940.042
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.041
Human Mouse
intracellular receptor signaling pathwayGO:0030522740.041
Mouse
nucleotide metabolic processGO:00091173320.041
negative regulation of tumor necrosis factor productionGO:0032720170.041
negative regulation of endothelial cell apoptotic processGO:200035270.040
negative regulation of interleukin 5 secretionGO:200066310.040
cytoplasmic transportGO:00164822340.040
regulation of protein complex assemblyGO:0043254830.040
regulation of interleukin 5 secretionGO:200066220.040
chemokine productionGO:0032602340.039
Mouse
cellular response to hormone stimulusGO:00328701500.039
establishment of protein localization to vacuoleGO:007266640.039
regulation of alpha beta t cell differentiationGO:0046637350.038
Mouse
cellular response to oxidative stressGO:0034599760.038
cellular response to type i interferonGO:0071357100.038
cellular response to lipoteichoic acidGO:007122360.038
Mouse
cytokine production involved in immune responseGO:0002367340.037
positive regulation of cellular amino acid metabolic processGO:004576430.037
regulation of toll like receptor signaling pathwayGO:0034121200.037
rhythmic processGO:00485111740.037
interleukin 6 productionGO:0032635580.037
Mouse
regulation of protein modification by small protein conjugation or removalGO:1903320570.037
mitochondrion organizationGO:00070051340.037
defense response to gram positive bacteriumGO:0050830500.036
Mouse
regulation of cell migrationGO:00303342190.036
Mouse
tissue homeostasisGO:00018941150.036
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.036
negative regulation of vascular endothelial growth factor receptor signaling pathwayGO:003094860.036
interleukin 12 biosynthetic processGO:004209080.035
nucleoside phosphate metabolic processGO:00067533380.035
regulation of nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043230.035
regulation of interleukin 1 productionGO:0032652260.035
cellular response to nitric oxideGO:007173240.035
toll like receptor signaling pathwayGO:0002224380.035
Mouse
purine nucleotide catabolic processGO:00061952110.035
negative regulation of interleukin 10 secretionGO:200118020.034
regulation of cytokine production involved in immune responseGO:0002718260.034
carboxylic acid transportGO:00469421000.034
immunoglobulin mediated immune responseGO:0016064690.034
anatomical structure homeostasisGO:00602491450.034
regulation of kinase activityGO:00435492490.034
regulation of multi organism processGO:00439001110.034
negative regulation of immune effector processGO:0002698550.034
positive regulation of fatty acid biosynthetic processGO:004572330.033
cellular homeostasisGO:00197252400.033
regulation of protein catabolic processGO:00421761080.033
positive regulation of chemokine productionGO:0032722220.033
Mouse
respiratory tube developmentGO:00303231670.033
regulation of endothelial cell apoptotic processGO:200035190.033
positive regulation of protein secretionGO:0050714520.033
carbohydrate metabolic processGO:00059752300.033
leukocyte mediated cytotoxicityGO:0001909620.032
Mouse
cellular response to tumor necrosis factorGO:0071356210.032
Human
cellular response to inorganic substanceGO:0071241370.032
positive regulation of protein transportGO:0051222930.032
positive regulation of cytokine biosynthetic processGO:0042108400.032
rna processingGO:00063961050.032
tube formationGO:00351481400.031
positive regulation of type i interferon mediated signaling pathwayGO:006034040.031
regulation of response to biotic stimulusGO:0002831380.031
innate immune responseGO:00450871570.031
Mouse
positive regulation of necrotic cell deathGO:001094010.031
Human Mouse
tumor necrosis factor superfamily cytokine productionGO:0071706510.030
Human Mouse
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239260.030
response to organic cyclic compoundGO:00140701980.030
Mouse
thymus developmentGO:0048538410.030
Mouse
protein homooligomerizationGO:0051260430.030
Human
negative regulation of phosphate metabolic processGO:00459361840.030
nucleocytoplasmic transportGO:00069131390.030
transmembrane transportGO:00550854120.030
Human
gland developmentGO:00487323300.030
Mouse
compound eye developmentGO:004874910.030
modification dependent protein catabolic processGO:00199411330.029
alcohol metabolic processGO:00060661160.029
response to radiationGO:00093141650.029
regulation of interferon beta biosynthetic processGO:004535740.029
positive regulation of erk1 and erk2 cascadeGO:0070374470.028
Mouse
negative regulation of t cell proliferationGO:0042130380.028
regulation of ketone biosynthetic processGO:001056620.028
interleukin 23 productionGO:003262720.028
regulation of cd4 positive alpha beta t cell activationGO:2000514240.028
Mouse
nucleoside metabolic processGO:00091162460.028
positive regulation of cytokine secretionGO:0050715410.028
epithelial tube formationGO:00721751300.028
response to type i interferonGO:0034340120.028
toll like receptor 4 signaling pathwayGO:003414290.028
Mouse
b cell activationGO:00421131610.028
muscle cell differentiationGO:00426922610.028
morphogenesis of embryonic epitheliumGO:00163311590.028
tube closureGO:0060606910.028
positive regulation of protein homodimerization activityGO:009007310.027
negative regulation of apoptotic signaling pathwayGO:20012341040.027
carboxylic acid biosynthetic processGO:0046394860.027
response to uvGO:0009411440.027
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.027
Mouse
peptidyl tyrosine modificationGO:00182121450.027
nucleobase containing small molecule metabolic processGO:00550863520.027
odontogenesis of dentin containing toothGO:0042475660.027
nuclear transportGO:00511691390.026
regulation of type i interferon mediated signaling pathwayGO:006033870.026
extracellular structure organizationGO:00430621480.026
response to inorganic substanceGO:0010035960.026
steroid metabolic processGO:00082021190.025
nucleic acid phosphodiester bond hydrolysisGO:0090305490.025
wnt signaling pathwayGO:00160551880.025
ubiquitin dependent protein catabolic processGO:00065111290.025
blood circulationGO:00080151950.025
interferon beta biosynthetic processGO:004535040.025
positive regulation of epithelial cell proliferationGO:0050679680.025
regulation of myeloid cell differentiationGO:0045637960.025
Human
purine ribonucleoside triphosphate metabolic processGO:00092052200.024
regulation of immunoglobulin secretionGO:0051023120.024
pattern recognition receptor signaling pathwayGO:0002221470.024
Mouse
coenzyme biosynthetic processGO:0009108230.024
extracellular matrix organizationGO:00301981470.024
positive regulation of protein complex assemblyGO:0031334450.024
interleukin 1 productionGO:0032612310.024
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.024
small molecule biosynthetic processGO:00442831320.024
organic cyclic compound catabolic processGO:19013612950.024
regulation of jun kinase activityGO:0043506400.024
cellular response to estrogen stimulusGO:0071391120.024
negative regulation of t cell apoptotic processGO:0070233180.024
regulation of map kinase activityGO:00434051200.024
tyrosine phosphorylation of stat1 proteinGO:004250830.024
guanosine containing compound metabolic processGO:19010681440.023
establishment of protein localization to organelleGO:00725941180.023
lipid storageGO:0019915360.023
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.023
regulation of neuron differentiationGO:00456642810.023
organelle localizationGO:00516401790.023
positive regulation of protein phosphorylationGO:00019342420.023
Human
sterol metabolic processGO:0016125580.023
regulation of cytoskeleton organizationGO:00514931220.023
angiogenesisGO:00015252010.023
positive regulation of secretion by cellGO:19035321140.023
regulation of cellular amine metabolic processGO:0033238200.023
acute inflammatory responseGO:0002526410.023
endocytosisGO:00068971680.022
regulation of blood pressureGO:0008217930.022
syncytium formation by plasma membrane fusionGO:0000768420.022
positive regulation of nucleotide metabolic processGO:00459811140.022
response to amino acidGO:0043200370.022
positive regulation of t cell cytokine productionGO:000272650.022
positive regulation of interferon beta productionGO:003272880.022
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.022
epithelial cell developmentGO:00020641590.022
regulation of leukocyte apoptotic processGO:2000106560.022
Mouse
nucleoside phosphate catabolic processGO:19012922220.022
negative regulation of cell cycleGO:00457861230.022
odontogenesisGO:0042476780.022
regulation of type i interferon productionGO:0032479220.022
detection of stimulusGO:0051606840.021
response to acid chemicalGO:00011011110.021
regulation of body fluid levelsGO:00508781620.021
wound healing involved in inflammatory responseGO:000224640.021
response to nitric oxideGO:007173140.021
monocarboxylic acid biosynthetic processGO:0072330610.021
purine nucleoside catabolic processGO:00061522050.021
cellular ion homeostasisGO:00068731650.021
myeloid dendritic cell differentiationGO:0043011160.021
purine containing compound metabolic processGO:00725213110.021
regulation of notch signaling pathwayGO:0008593350.021
modification dependent macromolecule catabolic processGO:00436321330.021
rho protein signal transductionGO:0007266320.021
purine ribonucleotide metabolic processGO:00091502900.021
tumor necrosis factor productionGO:0032640500.021
Human Mouse
negative regulation of lymphocyte apoptotic processGO:0070229240.021
interleukin 13 secretionGO:007261120.021
signal transduction in absence of ligandGO:0038034550.021
regulation of actin cytoskeleton organizationGO:0032956840.020
lipid biosynthetic processGO:00086101790.020
regulation of protein ubiquitinationGO:0031396520.020
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.020
purine nucleoside triphosphate catabolic processGO:00091462030.020
ribonucleoside triphosphate metabolic processGO:00091992200.020
endoplasmic reticulum unfolded protein responseGO:0030968190.020
protein processingGO:00164851630.020
regulation of immunoglobulin productionGO:0002637420.020
coenzyme metabolic processGO:0006732520.020
regulation of cytoplasmic transportGO:19036491120.020
regulation of metal ion transportGO:00109591060.020
regulation of vesicle mediated transportGO:00606271390.020
cell recognitionGO:0008037830.020
positive regulation of protein homooligomerizationGO:003246430.020
lipid transportGO:0006869980.020
small gtpase mediated signal transductionGO:0007264970.020
ribonucleoside triphosphate catabolic processGO:00092031990.019
regulation of t cell differentiationGO:0045580830.019
Mouse

Ripk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.544
cancerDOID:16200.354
organ system cancerDOID:005068600.354
disease of anatomical entityDOID:700.053
nervous system diseaseDOID:86300.053
immune system cancerDOID:006008300.042
hematologic cancerDOID:253100.042
respiratory system cancerDOID:005061500.020
lung cancerDOID:132400.020
central nervous system diseaseDOID:33100.020
neurodegenerative diseaseDOID:128900.020
immune system diseaseDOID:291400.020