| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.803 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.744 | |
| cellular response to interleukin 4 | GO:0071353 | 21 | 0.668 | |
| nucleobase containing compound transport | GO:0015931 | 27 | 0.625 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.622 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.602 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.494 | |
| translational elongation | GO:0006414 | 12 | 0.467 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.430 | |
| ribonucleoprotein complex subunit organization | GO:0071826 | 28 | 0.424 | Rat |
| negative regulation of phagocytosis | GO:0050765 | 4 | 0.401 | |
| regulation of translational elongation | GO:0006448 | 4 | 0.388 | |
| translation | GO:0006412 | 93 | 0.314 | Rat |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.290 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.287 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.279 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.267 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.256 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.248 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.248 | |
| cellular response to oxidative stress | GO:0034599 | 76 | 0.247 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.239 | |
| response to oxidative stress | GO:0006979 | 123 | 0.232 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.209 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.208 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.185 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.180 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.179 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.178 | |
| positive regulation of protein oligomerization | GO:0032461 | 4 | 0.174 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.164 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.156 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.154 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.150 | |
| angiogenesis | GO:0001525 | 201 | 0.149 | |
| gtp catabolic process | GO:0006184 | 143 | 0.141 | |
| regulation of protein oligomerization | GO:0032459 | 4 | 0.134 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.132 | |
| response to interleukin 4 | GO:0070670 | 23 | 0.129 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.128 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.126 | |
| response to epidermal growth factor | GO:0070849 | 4 | 0.121 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.120 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.117 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.117 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.113 | |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.110 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.108 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.105 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.104 | |
| regulation of gtp catabolic process | GO:0033124 | 113 | 0.103 | |
| camp catabolic process | GO:0006198 | 4 | 0.097 | |
| positive regulation of gtp catabolic process | GO:0033126 | 85 | 0.096 | |
| gonad development | GO:0008406 | 141 | 0.089 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.088 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 88 | 0.087 | |
| cellular homeostasis | GO:0019725 | 240 | 0.084 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.080 | |
| gtp metabolic process | GO:0046039 | 144 | 0.080 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.080 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.080 | |
| regulation of nucleoside metabolic process | GO:0009118 | 130 | 0.079 | |
| regulation of response to reactive oxygen species | GO:1901031 | 9 | 0.079 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.078 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.077 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.074 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.074 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.072 | |
| energy derivation by oxidation of organic compounds | GO:0015980 | 77 | 0.070 | |
| protein secretion | GO:0009306 | 111 | 0.070 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.069 | |
| regulation of glucose metabolic process | GO:0010906 | 60 | 0.068 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.067 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.066 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.065 | |
| amine metabolic process | GO:0009308 | 45 | 0.065 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.054 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.054 | |
| regulation of protein localization | GO:0032880 | 231 | 0.052 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.052 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.052 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 114 | 0.052 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.050 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.050 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.050 | |
| chromatin organization | GO:0006325 | 206 | 0.050 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.050 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.050 | |
| regulation of protein localization to plasma membrane | GO:1903076 | 13 | 0.049 | |
| regulation of glucan biosynthetic process | GO:0010962 | 7 | 0.049 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.048 | |
| regulation of cellular component size | GO:0032535 | 121 | 0.046 | |
| multicellular organism growth | GO:0035264 | 161 | 0.046 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 61 | 0.045 | |
| cytoplasmic translation | GO:0002181 | 7 | 0.043 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.043 | |
| regulation of carbohydrate biosynthetic process | GO:0043255 | 40 | 0.043 | |
| regulation of cell motility | GO:2000145 | 236 | 0.042 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.042 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.040 | |
| regulation of cellular protein catabolic process | GO:1903362 | 61 | 0.040 | |
| centrosome cycle | GO:0007098 | 23 | 0.040 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 114 | 0.039 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.039 | |
| positive regulation of gtpase activity | GO:0043547 | 85 | 0.039 | |
| nuclear transport | GO:0051169 | 139 | 0.038 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 91 | 0.038 | |
| pancreas development | GO:0031016 | 57 | 0.038 | |
| membrane depolarization | GO:0051899 | 64 | 0.036 | |
| membrane organization | GO:0061024 | 245 | 0.036 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.036 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.035 | |
| negative regulation of hydrogen peroxide induced cell death | GO:1903206 | 5 | 0.035 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.034 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.034 | |
| transmembrane transport | GO:0055085 | 412 | 0.033 | |
| cation transport | GO:0006812 | 399 | 0.033 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.032 | |
| muscle cell cellular homeostasis | GO:0046716 | 12 | 0.032 | |
| peptidyl lysine acetylation | GO:0018394 | 45 | 0.032 | |
| neural tube formation | GO:0001841 | 108 | 0.032 | |
| anatomical structure homeostasis | GO:0060249 | 145 | 0.031 | |
| regulation of translation | GO:0006417 | 71 | 0.031 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.031 | |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.031 | |
| establishment or maintenance of cell polarity | GO:0007163 | 86 | 0.030 | |
| rna localization | GO:0006403 | 23 | 0.030 | |
| dna metabolic process | GO:0006259 | 303 | 0.030 | |
| nucleic acid transport | GO:0050657 | 18 | 0.029 | |
| regulation of endocytosis | GO:0030100 | 69 | 0.029 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 95 | 0.029 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.029 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.029 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.028 | |
| hemostasis | GO:0007599 | 78 | 0.028 | |
| establishment of protein localization to membrane | GO:0090150 | 54 | 0.028 | |
| cell adhesion | GO:0007155 | 329 | 0.027 | |
| mitochondrial depolarization | GO:0051882 | 6 | 0.027 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.027 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.027 | |
| microtubule organizing center organization | GO:0031023 | 28 | 0.026 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.026 | |
| regulation of camp metabolic process | GO:0030814 | 30 | 0.026 | |
| protein catabolic process | GO:0030163 | 221 | 0.026 | |
| regulation of translational fidelity | GO:0006450 | 2 | 0.025 | |
| regulation of phagocytosis | GO:0050764 | 33 | 0.025 | |
| positive regulation of viral genome replication | GO:0045070 | 2 | 0.025 | |
| nuclear export | GO:0051168 | 34 | 0.025 | |
| polysaccharide metabolic process | GO:0005976 | 39 | 0.024 | |
| response to growth factor | GO:0070848 | 198 | 0.024 | |
| endocytosis | GO:0006897 | 168 | 0.024 | |
| neuron death | GO:0070997 | 154 | 0.024 | |
| regulation of glycogen biosynthetic process | GO:0005979 | 7 | 0.024 | |
| receptor mediated endocytosis | GO:0006898 | 51 | 0.024 | |
| ribosomal small subunit assembly | GO:0000028 | 1 | 0.024 | Rat |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.023 | |
| cyclic nucleotide metabolic process | GO:0009187 | 59 | 0.023 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.023 | |
| establishment of rna localization | GO:0051236 | 18 | 0.023 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 143 | 0.023 | |
| regulation of endopeptidase activity | GO:0052548 | 89 | 0.023 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.023 | |
| regulation of mitochondrial depolarization | GO:0051900 | 5 | 0.023 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.022 | |
| positive regulation of secretion | GO:0051047 | 130 | 0.022 | |
| regulation of cellular response to oxidative stress | GO:1900407 | 19 | 0.022 | |
| positive regulation of glycogen biosynthetic process | GO:0045725 | 6 | 0.022 | |
| glycogen biosynthetic process | GO:0005978 | 14 | 0.022 | |
| polysaccharide biosynthetic process | GO:0000271 | 20 | 0.021 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.021 | |
| regulation of cell activation | GO:0050865 | 289 | 0.021 | |
| locomotory behavior | GO:0007626 | 195 | 0.021 | |
| carbohydrate biosynthetic process | GO:0016051 | 74 | 0.021 | |
| generation of precursor metabolites and energy | GO:0006091 | 103 | 0.021 | |
| positive regulation of cyclic nucleotide metabolic process | GO:0030801 | 24 | 0.021 | |
| regulation of secretion | GO:0051046 | 274 | 0.020 | |
| oxidation reduction process | GO:0055114 | 342 | 0.020 | |
| regulation of cellular carbohydrate metabolic process | GO:0010675 | 75 | 0.020 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.020 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.020 | |
| regulation of body fluid levels | GO:0050878 | 162 | 0.020 | |
| regulation of ion homeostasis | GO:2000021 | 64 | 0.020 | |
| dna repair | GO:0006281 | 107 | 0.020 | |
| ribosomal large subunit assembly | GO:0000027 | 2 | 0.020 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.019 | |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.019 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.019 | |
| stem cell development | GO:0048864 | 219 | 0.019 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.019 | |
| histone modification | GO:0016570 | 159 | 0.019 | |
| glucan biosynthetic process | GO:0009250 | 14 | 0.019 | |
| microtubule based process | GO:0007017 | 236 | 0.019 | |
| nucleoside phosphate biosynthetic process | GO:1901293 | 79 | 0.019 | |
| response to inorganic substance | GO:0010035 | 96 | 0.019 | |
| macroautophagy | GO:0016236 | 21 | 0.018 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.018 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.018 | |
| peptidyl tyrosine modification | GO:0018212 | 145 | 0.018 | |
| ossification | GO:0001503 | 216 | 0.018 | |
| negative regulation of neuron death | GO:1901215 | 98 | 0.018 | |
| positive regulation of nucleotide catabolic process | GO:0030813 | 88 | 0.018 | |
| internal peptidyl lysine acetylation | GO:0018393 | 42 | 0.018 | |
| organophosphate biosynthetic process | GO:0090407 | 122 | 0.017 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.017 | |
| positive regulation of cell migration | GO:0030335 | 109 | 0.017 | |
| reactive nitrogen species metabolic process | GO:2001057 | 0 | 0.017 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.017 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.017 | |
| cellular glucan metabolic process | GO:0006073 | 32 | 0.016 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.016 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.016 | |
| negative regulation of oxidative stress induced cell death | GO:1903202 | 9 | 0.016 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.016 | |
| plasma membrane organization | GO:0007009 | 90 | 0.016 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.016 | |
| cellular response to extracellular stimulus | GO:0031668 | 81 | 0.016 | |
| regulation of cell migration | GO:0030334 | 219 | 0.016 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.016 | |
| negative regulation of oxidative stress induced neuron death | GO:1903204 | 2 | 0.015 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.015 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.015 | |
| regulation of homeostatic process | GO:0032844 | 182 | 0.015 | |
| multi multicellular organism process | GO:0044706 | 109 | 0.015 | |
| positive regulation of protein homooligomerization | GO:0032464 | 3 | 0.015 | |
| posttranscriptional gene silencing | GO:0016441 | 10 | 0.015 | |
| interspecies interaction between organisms | GO:0044419 | 83 | 0.015 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.015 | |
| regulation of feeding behavior | GO:0060259 | 3 | 0.015 | |
| regulation of cell growth | GO:0001558 | 91 | 0.015 | |
| defecation | GO:0030421 | 1 | 0.015 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.015 | |
| cellular carbohydrate metabolic process | GO:0044262 | 119 | 0.015 | |
| camp metabolic process | GO:0046058 | 40 | 0.015 | |
| protein oligomerization | GO:0051259 | 67 | 0.015 | |
| positive regulation of cysteine type endopeptidase activity | GO:2001056 | 39 | 0.014 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.014 | |
| protein maturation | GO:0051604 | 176 | 0.014 | |
| glucose metabolic process | GO:0006006 | 92 | 0.014 | |
| germ cell development | GO:0007281 | 185 | 0.014 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.014 | |
| morphogenesis of a branching structure | GO:0001763 | 203 | 0.014 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.014 | |
| cation homeostasis | GO:0055080 | 212 | 0.014 | |
| protein localization to plasma membrane | GO:0072659 | 57 | 0.014 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.014 | |
| reactive oxygen species biosynthetic process | GO:1903409 | 8 | 0.013 | |
| regulation of tube size | GO:0035150 | 57 | 0.013 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.013 | |
| gland development | GO:0048732 | 330 | 0.013 | |
| positive regulation of secretion by cell | GO:1903532 | 114 | 0.013 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.013 | |
| carboxylic acid biosynthetic process | GO:0046394 | 86 | 0.013 | |
| regulation of protein homooligomerization | GO:0032462 | 3 | 0.013 | |
| ribosome biogenesis | GO:0042254 | 20 | 0.013 | Rat |
| purine nucleotide biosynthetic process | GO:0006164 | 65 | 0.012 | |
| protein kinase b signaling | GO:0043491 | 74 | 0.012 | |
| regulation of gastrulation | GO:0010470 | 16 | 0.012 | |
| lipid particle organization | GO:0034389 | 7 | 0.012 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.012 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.012 | |
| response to hydrogen peroxide | GO:0042542 | 32 | 0.012 | |
| anion transport | GO:0006820 | 177 | 0.012 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 94 | 0.012 | |
| cytokine production | GO:0001816 | 319 | 0.012 | |
| cellular alcohol metabolic process | GO:0044107 | 3 | 0.012 | |
| regulation of oxidative stress induced cell death | GO:1903201 | 14 | 0.012 | |
| cellular response to gamma radiation | GO:0071480 | 4 | 0.012 | |
| viral process | GO:0016032 | 41 | 0.012 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 122 | 0.012 | |
| rna interference | GO:0016246 | 2 | 0.012 | |
| regulation of neuron death | GO:1901214 | 134 | 0.012 | |
| positive regulation of carbohydrate metabolic process | GO:0045913 | 30 | 0.012 | |
| rna processing | GO:0006396 | 105 | 0.012 | |
| maintenance of location | GO:0051235 | 89 | 0.011 | |
| blood coagulation | GO:0007596 | 76 | 0.011 | |
| regulation of cell size | GO:0008361 | 72 | 0.011 | |
| regulation of protein secretion | GO:0050708 | 82 | 0.011 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.011 | |
| lipid localization | GO:0010876 | 126 | 0.011 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.011 | |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.011 | |
| cell death in response to oxidative stress | GO:0036473 | 24 | 0.011 | |
| regulation of peptidyl tyrosine phosphorylation | GO:0050730 | 93 | 0.011 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.011 | |
| regulation of polysaccharide biosynthetic process | GO:0032885 | 7 | 0.011 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.011 | |
| negative regulation of cell growth | GO:0030308 | 44 | 0.011 | |
| positive regulation of protein secretion | GO:0050714 | 52 | 0.011 | |
| cellular metal ion homeostasis | GO:0006875 | 151 | 0.011 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.011 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.011 | |
| negative regulation of response to oxidative stress | GO:1902883 | 10 | 0.010 | |
| response to amino acid | GO:0043200 | 37 | 0.010 | |
| positive regulation of intrinsic apoptotic signaling pathway | GO:2001244 | 25 | 0.010 | |
| negative regulation of wnt signaling pathway | GO:0030178 | 73 | 0.010 | |
| muscle fiber development | GO:0048747 | 76 | 0.010 | |
| peptidyl lysine modification | GO:0018205 | 77 | 0.010 | |
| chromatin modification | GO:0016568 | 187 | 0.010 | |
| regulation of blood pressure | GO:0008217 | 93 | 0.010 | |
| response to nutrient levels | GO:0031667 | 109 | 0.010 | |
| peptidyl proline modification | GO:0018208 | 6 | 0.010 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.010 | |
| smooth muscle contraction | GO:0006939 | 44 | 0.010 | |
