| positive regulation of peptide secretion | GO:0002793 | 33 | 0.763 | |
| regulation of neuronal synaptic plasticity | GO:0048168 | 30 | 0.636 | |
| regulation of synaptic plasticity | GO:0048167 | 87 | 0.516 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.472 | |
| regulation of secretion | GO:0051046 | 274 | 0.465 | |
| plasma membrane organization | GO:0007009 | 90 | 0.389 | |
| regulation of integrin biosynthetic process | GO:0045113 | 1 | 0.364 | |
| regulation of voltage gated calcium channel activity | GO:1901385 | 4 | 0.355 | |
| integrin biosynthetic process | GO:0045112 | 1 | 0.313 | |
| synaptic transmission | GO:0007268 | 329 | 0.296 | |
| membrane organization | GO:0061024 | 245 | 0.274 | |
| endomembrane system organization | GO:0010256 | 147 | 0.238 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.182 | |
| cation transport | GO:0006812 | 399 | 0.176 | |
| immune effector process | GO:0002252 | 321 | 0.151 | |
| cellular response to acid chemical | GO:0071229 | 68 | 0.150 | |
| cognition | GO:0050890 | 149 | 0.147 | |
| regulation of peptide transport | GO:0090087 | 91 | 0.146 | |
| peptide transport | GO:0015833 | 133 | 0.137 | |
| response to acid chemical | GO:0001101 | 111 | 0.125 | |
| regulation of peptide secretion | GO:0002791 | 77 | 0.122 | |
| calcium ion transmembrane transport | GO:0070588 | 85 | 0.119 | |
| regulation of transmembrane transport | GO:0034762 | 128 | 0.106 | |
| positive regulation of secretion | GO:0051047 | 130 | 0.102 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.100 | |
| peptide secretion | GO:0002790 | 114 | 0.099 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.092 | |
| transmembrane transport | GO:0055085 | 412 | 0.092 | |
| regulation of ion transmembrane transporter activity | GO:0032412 | 54 | 0.085 | |
| t cell activation | GO:0042110 | 289 | 0.082 | |
| cation homeostasis | GO:0055080 | 212 | 0.081 | |
| memory | GO:0007613 | 58 | 0.079 | |
| actin cytoskeleton reorganization | GO:0031532 | 21 | 0.075 | |
| amide transport | GO:0042886 | 138 | 0.074 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.073 | |
| regulation of peptidase activity | GO:0052547 | 96 | 0.066 | |
| regulation of ion transmembrane transport | GO:0034765 | 119 | 0.065 | |
| regulation of vesicle mediated transport | GO:0060627 | 139 | 0.064 | |
| cell chemotaxis | GO:0060326 | 81 | 0.063 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.061 | |
| regulation of binding | GO:0051098 | 111 | 0.057 | |
| calcium ion homeostasis | GO:0055074 | 127 | 0.056 | |
| regulation of ion transport | GO:0043269 | 215 | 0.056 | |
| divalent metal ion transport | GO:0070838 | 172 | 0.055 | |
| cellular metal ion homeostasis | GO:0006875 | 151 | 0.054 | |
| circadian sleep wake cycle rem sleep | GO:0042747 | 1 | 0.053 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.051 | |
| oxidation reduction process | GO:0055114 | 342 | 0.050 | |
| protein processing | GO:0016485 | 163 | 0.049 | |
| regulation of protein processing | GO:0070613 | 96 | 0.045 | |
| skeletal system development | GO:0001501 | 356 | 0.045 | |
| regulation of protein maturation | GO:1903317 | 96 | 0.044 | |
| protein maturation | GO:0051604 | 176 | 0.044 | |
| regulation of cation channel activity | GO:2001257 | 22 | 0.042 | |
| leukocyte activation involved in immune response | GO:0002366 | 126 | 0.040 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.040 | |
| positive regulation of voltage gated calcium channel activity | GO:1901387 | 2 | 0.039 | |
| regulation of calcium ion transmembrane transporter activity | GO:1901019 | 20 | 0.038 | |
| learning or memory | GO:0007611 | 148 | 0.038 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.037 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.036 | |
| membrane raft assembly | GO:0001765 | 3 | 0.036 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.035 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.035 | |
| organelle membrane fusion | GO:0090174 | 1 | 0.033 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.032 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.032 | |
| leukocyte chemotaxis | GO:0030595 | 69 | 0.031 | |
| positive regulation of myeloid cell apoptotic process | GO:0033034 | 4 | 0.029 | |
| regulation of calcium ion transmembrane transport | GO:1903169 | 20 | 0.028 | |
| autophagic vacuole fusion | GO:0000046 | 1 | 0.028 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 127 | 0.028 | |
| negative regulation of protein maturation | GO:1903318 | 79 | 0.027 | |
| muscle contraction | GO:0006936 | 101 | 0.027 | |
| positive regulation of ion transmembrane transporter activity | GO:0032414 | 15 | 0.027 | |
| maintenance of epithelial cell apical basal polarity | GO:0045199 | 2 | 0.027 | |
| cellular homeostasis | GO:0019725 | 240 | 0.026 | |
| intracellular protein transport | GO:0006886 | 204 | 0.026 | |
| negative regulation of peptidase activity | GO:0010466 | 46 | 0.025 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.025 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.024 | |
| positive regulation of ion transmembrane transport | GO:0034767 | 24 | 0.024 | |
| chemotaxis | GO:0006935 | 247 | 0.024 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.024 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.024 | |
| lymphocyte differentiation | GO:0030098 | 242 | 0.024 | |
| protein localization to organelle | GO:0033365 | 185 | 0.023 | |
| innate immune response | GO:0045087 | 157 | 0.023 | |
| negative regulation of lymphocyte activation | GO:0051250 | 91 | 0.023 | |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 65 | 0.023 | |
| response to nutrient levels | GO:0031667 | 109 | 0.023 | |
| negative regulation of protein processing | GO:0010955 | 79 | 0.023 | |
| protein localization to membrane | GO:0072657 | 108 | 0.022 | |
| entry into cell of other organism involved in symbiotic interaction | GO:0051806 | 15 | 0.022 | |
| negative regulation of hydrolase activity | GO:0051346 | 71 | 0.022 | |
| vesicle fusion | GO:0006906 | 16 | 0.022 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.022 | |
| protein oligomerization | GO:0051259 | 67 | 0.022 | |
| negative regulation of endopeptidase activity | GO:0010951 | 44 | 0.021 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.021 | |
| activation of adenylate cyclase activity | GO:0007190 | 4 | 0.020 | |
| multi multicellular organism process | GO:0044706 | 109 | 0.020 | |
| carbon catabolite regulation of transcription | GO:0045990 | 4 | 0.020 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.020 | |
| cardiac muscle contraction | GO:0060048 | 32 | 0.020 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.020 | |
| cell activation involved in immune response | GO:0002263 | 126 | 0.020 | |
| regulation of vasculature development | GO:1901342 | 88 | 0.020 | |
| protein localization to plasma membrane | GO:0072659 | 57 | 0.020 | |
| type b pancreatic cell proliferation | GO:0044342 | 10 | 0.020 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.020 | |
| regulation of protein localization | GO:0032880 | 231 | 0.020 | |
| regulation of metal ion transport | GO:0010959 | 106 | 0.019 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.019 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.019 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.019 | |
| circulatory system process | GO:0003013 | 197 | 0.019 | |
| calcium ion transport | GO:0006816 | 159 | 0.019 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.019 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.018 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.018 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.018 | |
| myosin filament organization | GO:0031033 | 3 | 0.018 | |
| regulation of immunological synapse formation | GO:2000520 | 2 | 0.018 | |
| regulation of neutrophil apoptotic process | GO:0033029 | 1 | 0.018 | |
| muscle system process | GO:0003012 | 141 | 0.018 | |
| positive regulation of cell projection organization | GO:0031346 | 95 | 0.018 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.018 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.018 | |
| detection of muscle stretch | GO:0035995 | 1 | 0.018 | |
| regulation of cell activation | GO:0050865 | 289 | 0.018 | |
| entry into host | GO:0044409 | 15 | 0.017 | |
| maintenance of apical basal cell polarity | GO:0035090 | 3 | 0.017 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.017 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.017 | |
| response to muscle stretch | GO:0035994 | 1 | 0.017 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.017 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.017 | |
| cellular response to hepatocyte growth factor stimulus | GO:0035729 | 2 | 0.017 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.017 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.017 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.017 | |
| muscle tissue development | GO:0060537 | 308 | 0.016 | |
| plasma cell differentiation | GO:0002317 | 3 | 0.016 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.016 | |
| vesicle organization | GO:0016050 | 60 | 0.016 | |
| positive regulation of transmembrane transport | GO:0034764 | 29 | 0.016 | |
| respiratory system development | GO:0060541 | 190 | 0.016 | |
| organic hydroxy compound transport | GO:0015850 | 93 | 0.016 | |
| intrinsic apoptotic signaling pathway in response to dna damage | GO:0008630 | 57 | 0.016 | |
| entry into other organism involved in symbiotic interaction | GO:0051828 | 15 | 0.016 | |
| t cell mediated immunity | GO:0002456 | 50 | 0.016 | |
| negative regulation of proteolysis | GO:0045861 | 74 | 0.016 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.016 | |
| respiratory tube development | GO:0030323 | 167 | 0.016 | |
| lymphocyte mediated immunity | GO:0002449 | 139 | 0.016 | |
| positive regulation of nervous system development | GO:0051962 | 221 | 0.016 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.016 | |
| mitochondrion organization | GO:0007005 | 134 | 0.016 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.016 | |
| positive regulation of calcium ion transmembrane transporter activity | GO:1901021 | 8 | 0.016 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.016 | |
| cellular response to antibiotic | GO:0071236 | 4 | 0.015 | |
| leukocyte proliferation | GO:0070661 | 172 | 0.015 | |
| circadian rhythm | GO:0007623 | 114 | 0.015 | |
| response to inorganic substance | GO:0010035 | 96 | 0.015 | Mouse |
| inflammatory response | GO:0006954 | 244 | 0.015 | |
| defense response to other organism | GO:0098542 | 197 | 0.015 | |
| positive regulation of cell motility | GO:2000147 | 116 | 0.015 | |
| regulation of homeostatic process | GO:0032844 | 182 | 0.015 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.015 | |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.015 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.015 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.015 | |
| positive regulation of rac protein signal transduction | GO:0035022 | 1 | 0.015 | |
| actin filament organization | GO:0007015 | 113 | 0.015 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.014 | |
| cellular calcium ion homeostasis | GO:0006874 | 119 | 0.014 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.014 | |
| lipid transport | GO:0006869 | 98 | 0.014 | |
| entry into host cell | GO:0030260 | 15 | 0.014 | |
| glucose homeostasis | GO:0042593 | 128 | 0.014 | |
| regulation of protein transport | GO:0051223 | 163 | 0.014 | |
| regulation of neuron projection development | GO:0010975 | 169 | 0.014 | |
| regulation of angiogenesis | GO:0045765 | 81 | 0.014 | |
| angiogenesis | GO:0001525 | 201 | 0.014 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.014 | |
| positive regulation of reactive oxygen species biosynthetic process | GO:1903428 | 2 | 0.013 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.013 | |
| regulation of calcium ion transport | GO:0051924 | 69 | 0.013 | |
| regulation of cell motility | GO:2000145 | 236 | 0.013 | |
| negative regulation of immunological synapse formation | GO:2000521 | 1 | 0.013 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.013 | |
| interspecies interaction between organisms | GO:0044419 | 83 | 0.013 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.013 | |
| response to light stimulus | GO:0009416 | 135 | 0.013 | |
| spermatogenesis | GO:0007283 | 284 | 0.013 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 114 | 0.013 | |
| mapk cascade | GO:0000165 | 281 | 0.013 | |
| negative regulation of glycoprotein metabolic process | GO:1903019 | 3 | 0.013 | |
| maintenance of location | GO:0051235 | 89 | 0.013 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.013 | |
| extracellular matrix organization | GO:0030198 | 147 | 0.013 | |
| defense response to bacterium | GO:0042742 | 119 | 0.013 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.013 | |
| male gamete generation | GO:0048232 | 285 | 0.013 | |
| cytokine production | GO:0001816 | 319 | 0.012 | Human |
| cellular response to nutrient levels | GO:0031669 | 64 | 0.012 | |
| nuclear transport | GO:0051169 | 139 | 0.012 | |
| dna metabolic process | GO:0006259 | 303 | 0.012 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.012 | |
| hormone secretion | GO:0046879 | 128 | 0.012 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.012 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.012 | |
| t cell differentiation | GO:0030217 | 174 | 0.012 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.012 | |
| leukocyte migration | GO:0050900 | 124 | 0.012 | |
| negative regulation of cell activation | GO:0050866 | 111 | 0.012 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.012 | |
| regulation of endocytosis | GO:0030100 | 69 | 0.012 | |
| detection of stimulus | GO:0051606 | 84 | 0.012 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.012 | |
| regulation of system process | GO:0044057 | 200 | 0.012 | |
| primitive erythrocyte differentiation | GO:0060319 | 3 | 0.012 | |
| response to radiation | GO:0009314 | 165 | 0.012 | |
| detection of abiotic stimulus | GO:0009582 | 60 | 0.012 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.012 | |
| divalent inorganic cation homeostasis | GO:0072507 | 138 | 0.012 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.011 | |
| myeloid cell homeostasis | GO:0002262 | 114 | 0.011 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 139 | 0.011 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.011 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.011 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.011 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.011 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.011 | |
| lipid localization | GO:0010876 | 126 | 0.011 | |
| glycoprotein catabolic process | GO:0006516 | 5 | 0.011 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.011 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.011 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.011 | |
| movement in environment of other organism involved in symbiotic interaction | GO:0052192 | 15 | 0.011 | |
| regulation of response to wounding | GO:1903034 | 189 | 0.011 | |
| muscle cell development | GO:0055001 | 133 | 0.011 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.011 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.011 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.011 | |
| action potential | GO:0001508 | 78 | 0.011 | |
| interaction with host | GO:0051701 | 22 | 0.011 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.011 | |
| fibril organization | GO:0097435 | 2 | 0.011 | |
| lung development | GO:0030324 | 164 | 0.011 | |
| regulation of wound healing | GO:0061041 | 40 | 0.011 | |
| morphogenesis of a branching epithelium | GO:0061138 | 193 | 0.011 | |
| immune response activating cell surface receptor signaling pathway | GO:0002429 | 72 | 0.011 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.011 | |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.011 | |
| endocytosis | GO:0006897 | 168 | 0.011 | |
| sequestering of calcium ion | GO:0051208 | 18 | 0.011 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.011 | |
| regulation of interleukin 8 production | GO:0032677 | 3 | 0.010 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.010 | |
| heart process | GO:0003015 | 94 | 0.010 | |
| positive regulation of calcium ion transport | GO:0051928 | 27 | 0.010 | |
| ossification | GO:0001503 | 216 | 0.010 | |
| response to calcium ion | GO:0051592 | 20 | 0.010 | Mouse |
| t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell | GO:0002291 | 2 | 0.010 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.010 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.010 | |
