IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Sc4mol

sterol-C4-methyl oxidase-like

(Aliases: DESP4,1500001G16Rik,ERG25,C78600)

Ensembl: ENSMUSG00000031604
Entrez: 66234
UniProtKB: Q9CRA4

Process Predictions
Disease Predictions

Sc4mol biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
sterol metabolic process	GO:0016125	58	0.999	Yeast
cellular alcohol biosynthetic process	GO:0044108	3	0.997	Yeast
lipid biosynthetic process	GO:0008610	179	0.972	Yeast
alcohol biosynthetic process	GO:0046165	43	0.941	Yeast
alcohol metabolic process	GO:0006066	116	0.930	Yeast
small molecule biosynthetic process	GO:0044283	132	0.902	Yeast
cellular alcohol metabolic process	GO:0044107	3	0.834	Yeast
cellular lipid metabolic process	GO:0044255	323	0.800	Yeast
cholesterol biosynthetic process	GO:0006695	15	0.788
cholesterol metabolic process	GO:0008203	56	0.627
isoprenoid biosynthetic process	GO:0008299	9	0.626
steroid metabolic process	GO:0008202	119	0.606	Yeast
sterol biosynthetic process	GO:0016126	17	0.560	Yeast
oxidation reduction process	GO:0055114	342	0.445	Yeast
sterol transmembrane transport	GO:0035382	2	0.325
organic hydroxy compound biosynthetic process	GO:1901617	77	0.299	Yeast
response to phenylpropanoid	GO:0080184	22	0.295
isoprenoid metabolic process	GO:0006720	29	0.229
lipoprotein catabolic process	GO:0042159	7	0.228
regulation of phosphatidylcholine catabolic process	GO:0010899	2	0.224
long chain fatty acid metabolic process	GO:0001676	26	0.215
fatty acid elongation	GO:0030497	3	0.200
cellular biogenic amine metabolic process	GO:0006576	28	0.200
diterpenoid metabolic process	GO:0016101	24	0.171
organonitrogen compound biosynthetic process	GO:1901566	192	0.164
regulation of phospholipid catabolic process	GO:0060696	2	0.142
small molecule catabolic process	GO:0044282	71	0.135
organic anion transport	GO:0015711	137	0.127
organic hydroxy compound metabolic process	GO:1901615	203	0.124	Yeast
cellular ketone metabolic process	GO:0042180	84	0.118
regulation of hormone levels	GO:0010817	211	0.115
steroid biosynthetic process	GO:0006694	47	0.110	Yeast
response to yeast	GO:0001878	6	0.108
lipid homeostasis	GO:0055088	63	0.101
demethylation	GO:0070988	23	0.096
regulation of cellular amine metabolic process	GO:0033238	20	0.083
glycerophospholipid catabolic process	GO:0046475	5	0.083
sphingolipid biosynthetic process	GO:0030148	26	0.078
cellular amino acid metabolic process	GO:0006520	103	0.078
monocarboxylic acid metabolic process	GO:0032787	191	0.072
response to radiation	GO:0009314	165	0.069
lipid transport	GO:0006869	98	0.064
terpenoid metabolic process	GO:0006721	25	0.061
cholesterol import	GO:0070508	2	0.060
lipid localization	GO:0010876	126	0.055
regulation of lipid metabolic process	GO:0019216	118	0.055
cellular amine metabolic process	GO:0044106	44	0.052
liver development	GO:0001889	66	0.050
anion transport	GO:0006820	177	0.050
organophosphate catabolic process	GO:0046434	232	0.050
rhodopsin mediated signaling pathway	GO:0016056	4	0.050
phospholipid catabolic process	GO:0009395	5	0.049
triglyceride biosynthetic process	GO:0019432	17	0.048
positive regulation of cellular amine metabolic process	GO:0033240	5	0.048
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.047
negative regulation of molecular function	GO:0044092	258	0.046
regulation of cellular ketone metabolic process	GO:0010565	66	0.045
regulation of protein serine threonine kinase activity	GO:0071900	157	0.045
neutral lipid biosynthetic process	GO:0046460	18	0.044
amine metabolic process	GO:0009308	45	0.040
membrane lipid metabolic process	GO:0006643	53	0.038	Yeast
positive regulation of creb transcription factor activity	GO:0032793	4	0.038
sterol transport	GO:0015918	38	0.037
digestion	GO:0007586	40	0.037
response to organic cyclic compound	GO:0014070	198	0.037
positive regulation of triglyceride metabolic process	GO:0090208	9	0.036
regulation of cellular amino acid metabolic process	GO:0006521	5	0.035
monocarboxylic acid biosynthetic process	GO:0072330	61	0.035
response to nutrient levels	GO:0031667	109	0.034
regulation of transferase activity	GO:0051338	263	0.032
reelin mediated signaling pathway	GO:0038026	3	0.032
ketone body metabolic process	GO:1902224	3	0.032
organic hydroxy compound transport	GO:0015850	93	0.031
protein catabolic process	GO:0030163	221	0.031
negative regulation of synapse assembly	GO:0051964	3	0.030
skin development	GO:0043588	220	0.030
ribonucleotide metabolic process	GO:0009259	291	0.030
molting cycle	GO:0042303	90	0.029
regulation of cell cycle	GO:0051726	281	0.029
adaptation of rhodopsin mediated signaling	GO:0016062	2	0.029
mating behavior sex discrimination	GO:0048047	1	0.028
regulation of phospholipid biosynthetic process	GO:0071071	3	0.028
long chain fatty acid biosynthetic process	GO:0042759	5	0.028
regulation of organelle organization	GO:0033043	289	0.028
response to steroid hormone	GO:0048545	56	0.027
glutamate biosynthetic process	GO:0006537	2	0.027
negative regulation of multi organism process	GO:0043901	68	0.027
response to oxidative stress	GO:0006979	123	0.027
regulation of secretion	GO:0051046	274	0.026
visual behavior	GO:0007632	45	0.026
ras protein signal transduction	GO:0007265	77	0.026
nucleobase containing small molecule metabolic process	GO:0055086	352	0.026
positive regulation of protein modification process	GO:0031401	299	0.025
response to peptide	GO:1901652	136	0.025
detection of abiotic stimulus	GO:0009582	60	0.024
establishment or maintenance of bipolar cell polarity	GO:0061245	21	0.024
ribonucleoside metabolic process	GO:0009119	245	0.024
membrane lipid biosynthetic process	GO:0046467	32	0.023
response to light stimulus	GO:0009416	135	0.023
regulation of triglyceride metabolic process	GO:0090207	17	0.023
positive regulation of growth	GO:0045927	104	0.023
ion transmembrane transport	GO:0034220	361	0.023
sterol homeostasis	GO:0055092	45	0.022
g protein coupled receptor signaling pathway	GO:0007186	243	0.022
positive regulation of cell adhesion	GO:0045785	80	0.022
regulation of multi organism process	GO:0043900	111	0.022
forebrain development	GO:0030900	302	0.021
innate immune response	GO:0045087	157	0.021
maintenance of location	GO:0051235	89	0.021
mapk cascade	GO:0000165	281	0.021
nucleotide metabolic process	GO:0009117	332	0.021
ethanolamine containing compound metabolic process	GO:0042439	18	0.021
carbohydrate homeostasis	GO:0033500	128	0.021
small gtpase mediated signal transduction	GO:0007264	97	0.021
carbohydrate derivative biosynthetic process	GO:1901137	183	0.020
purine nucleotide metabolic process	GO:0006163	302	0.020
response to sterol	GO:0036314	4	0.020
regulation of cellular catabolic process	GO:0031329	242	0.020
organic acid transport	GO:0015849	101	0.019
fatty acid biosynthetic process	GO:0006633	41	0.019
asymmetric stem cell division	GO:0098722	3	0.019
coenzyme biosynthetic process	GO:0009108	23	0.019
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.019
dna metabolic process	GO:0006259	303	0.019
response to acid chemical	GO:0001101	111	0.019
learning	GO:0007612	98	0.019
establishment or maintenance of cytoskeleton polarity	GO:0030952	2	0.019
glycerolipid metabolic process	GO:0046486	122	0.019
positive regulation of cholesterol biosynthetic process	GO:0045542	3	0.019
positive regulation of lipid metabolic process	GO:0045834	40	0.019
regulation of homeostatic process	GO:0032844	182	0.019
locomotory behavior	GO:0007626	195	0.019
hormone metabolic process	GO:0042445	86	0.019
response to extracellular stimulus	GO:0009991	127	0.018
embryonic organ morphogenesis	GO:0048562	276	0.018
transmembrane transport	GO:0055085	412	0.018
fatty acid elongation unsaturated fatty acid	GO:0019368	2	0.018
sensory perception	GO:0007600	245	0.018
defense response to bacterium	GO:0042742	119	0.018
action potential	GO:0001508	78	0.018
organonitrogen compound catabolic process	GO:1901565	264	0.018
negative regulation of protein metabolic process	GO:0051248	282	0.018
positive regulation of cell development	GO:0010720	237	0.018
nadph regeneration	GO:0006740	2	0.018
purine ribonucleotide catabolic process	GO:0009154	208	0.017
regulation of cellular component biogenesis	GO:0044087	181	0.017
synaptic transmission	GO:0007268	329	0.017
regulation of system process	GO:0044057	200	0.017
multicellular organismal signaling	GO:0035637	91	0.017
metal ion homeostasis	GO:0055065	189	0.017
extracellular structure organization	GO:0043062	148	0.017
cation transmembrane transport	GO:0098655	266	0.017
chemotaxis	GO:0006935	247	0.017
myeloid cell differentiation	GO:0030099	233	0.016
glycosyl compound metabolic process	GO:1901657	246	0.016
asymmetric neuroblast division	GO:0055059	1	0.016
smoothened signaling pathway	GO:0007224	105	0.016
cellular response to nutrient levels	GO:0031669	64	0.016
protein modification by small protein conjugation	GO:0032446	187	0.016
response to monosaccharide	GO:0034284	67	0.016
regulation of kinase activity	GO:0043549	249	0.016
sphingolipid metabolic process	GO:0006665	45	0.016	Yeast
regulation of cell projection organization	GO:0031344	206	0.016
microtubule based process	GO:0007017	236	0.016
coenzyme a biosynthetic process	GO:0015937	5	0.016
transmission of nerve impulse	GO:0019226	76	0.016
regulation of peptidyl tyrosine phosphorylation	GO:0050730	93	0.016
circulatory system process	GO:0003013	197	0.016
regulation of protein kinase activity	GO:0045859	232	0.016
nucleoside phosphate metabolic process	GO:0006753	338	0.016
negative regulation of intracellular signal transduction	GO:1902532	167	0.016
positive regulation of transferase activity	GO:0051347	167	0.015
purine ribonucleoside metabolic process	GO:0046128	241	0.015
cytokine production	GO:0001816	319	0.015
positive regulation of protein phosphorylation	GO:0001934	242	0.015
retrograde transport endosome to golgi	GO:0042147	2	0.015
detection of light stimulus	GO:0009583	25	0.015
cellular amino acid biosynthetic process	GO:0008652	22	0.015
regulation of membrane potential	GO:0042391	192	0.015
male gamete generation	GO:0048232	285	0.015
carbohydrate derivative catabolic process	GO:1901136	231	0.015
cellular homeostasis	GO:0019725	240	0.015
ceramide metabolic process	GO:0006672	31	0.015
low density lipoprotein particle clearance	GO:0034383	8	0.015
regulation of neuron projection development	GO:0010975	169	0.015
purine containing compound metabolic process	GO:0072521	311	0.015
ribonucleotide biosynthetic process	GO:0009260	59	0.015
negative regulation of cellular component organization	GO:0051129	194	0.015
negative regulation of growth of symbiont in host	GO:0044130	19	0.014
regulation of neuron differentiation	GO:0045664	281	0.014
blood circulation	GO:0008015	195	0.014
ribose phosphate metabolic process	GO:0019693	291	0.014
axonogenesis	GO:0007409	274	0.014
positive regulation of protein kinase activity	GO:0045860	144	0.014
fatty acid oxidation	GO:0019395	28	0.014
regulation of plasma lipoprotein particle levels	GO:0097006	23	0.014
positive regulation of organelle organization	GO:0010638	128	0.014
activation of adenylate cyclase activity	GO:0007190	4	0.014
negative regulation of protein serine threonine kinase activity	GO:0071901	49	0.014
regulation of defense response	GO:0031347	233	0.014
positive regulation of mapk cascade	GO:0043410	170	0.014
engulfment of apoptotic cell	GO:0043652	3	0.014
regulation of ras protein signal transduction	GO:0046578	114	0.014
anatomical structure homeostasis	GO:0060249	145	0.014
leukocyte homeostasis	GO:0001776	79	0.014
camera type eye development	GO:0043010	266	0.014
nitrogen compound transport	GO:0071705	271	0.014
nucleoside phosphate catabolic process	GO:1901292	222	0.014
nucleoside triphosphate metabolic process	GO:0009141	230	0.014
organic cyclic compound catabolic process	GO:1901361	295	0.014
peptidyl amino acid modification	GO:0018193	336	0.013
glucose homeostasis	GO:0042593	128	0.013
negative regulation of cellular amine metabolic process	GO:0033239	1	0.013
ceramide biosynthetic process	GO:0046513	20	0.013
neuronal action potential	GO:0019228	54	0.013
sensory organ morphogenesis	GO:0090596	242	0.013
interleukin 8 production	GO:0032637	4	0.013
regulation of secretion by cell	GO:1903530	249	0.013
leukocyte differentiation	GO:0002521	342	0.013
cellular chemical homeostasis	GO:0055082	215	0.013
organelle assembly	GO:0070925	177	0.013
cellular calcium ion homeostasis	GO:0006874	119	0.013
female sex differentiation	GO:0046660	84	0.013
positive regulation of cell projection organization	GO:0031346	95	0.013
multi multicellular organism process	GO:0044706	109	0.013
carboxylic acid catabolic process	GO:0046395	51	0.013
multicellular organismal homeostasis	GO:0048871	164	0.013
cytoplasmic transport	GO:0016482	234	0.013
cellular response to carbohydrate stimulus	GO:0071322	50	0.013
methylation	GO:0032259	134	0.013
inorganic cation transmembrane transport	GO:0098662	207	0.013
positive regulation of nervous system development	GO:0051962	221	0.013
tissue homeostasis	GO:0001894	115	0.013
response to peptide hormone	GO:0043434	127	0.013
lipid modification	GO:0030258	65	0.013
inorganic ion transmembrane transport	GO:0098660	234	0.013
epidermis development	GO:0008544	187	0.012
cation transport	GO:0006812	399	0.012
positive regulation of neuron differentiation	GO:0045666	141	0.012
cellular nitrogen compound catabolic process	GO:0044270	280	0.012
positive regulation of secretion	GO:0051047	130	0.012
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	54	0.012
regulation of hydrolase activity	GO:0051336	246	0.012
chromatin organization	GO:0006325	206	0.012
carboxylic acid transport	GO:0046942	100	0.012
compound eye development	GO:0048749	1	0.012
negative regulation of phosphate metabolic process	GO:0045936	184	0.012
negative regulation of phosphorus metabolic process	GO:0010563	184	0.012
defense response to gram positive bacterium	GO:0050830	50	0.012
hair follicle development	GO:0001942	85	0.012
macromolecule catabolic process	GO:0009057	281	0.012
divalent metal ion transport	GO:0070838	172	0.012
ribonucleoside bisphosphate metabolic process	GO:0033875	9	0.012
purine nucleoside catabolic process	GO:0006152	205	0.012
growth involved in symbiotic interaction	GO:0044110	23	0.012
regulation of cell adhesion	GO:0030155	154	0.012
lipid oxidation	GO:0034440	29	0.012
alpha amino acid biosynthetic process	GO:1901607	15	0.012
erk1 and erk2 cascade	GO:0070371	77	0.012
regulation of anatomical structure size	GO:0090066	178	0.012
positive regulation of triglyceride biosynthetic process	GO:0010867	6	0.012
posttranscriptional regulation of gene expression	GO:0010608	155	0.011
cellular response to dna damage stimulus	GO:0006974	207	0.011
cell growth	GO:0016049	130	0.011
cellular response to organonitrogen compound	GO:0071417	145	0.011
negative regulation of cellular protein metabolic process	GO:0032269	247	0.011
rhythmic process	GO:0048511	174	0.011
cerebral cortex development	GO:0021987	86	0.011
calcium ion homeostasis	GO:0055074	127	0.011
cellular response to organic cyclic compound	GO:0071407	87	0.011
response to starvation	GO:0042594	65	0.011
blood vessel morphogenesis	GO:0048514	285	0.011
extracellular matrix organization	GO:0030198	147	0.011
t cell activation	GO:0042110	289	0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	112	0.011
appendage development	GO:0048736	166	0.011
dendrite development	GO:0016358	115	0.011
spermatogenesis	GO:0007283	284	0.011
myeloid leukocyte differentiation	GO:0002573	119	0.011
fat cell differentiation	GO:0045444	160	0.011
aromatic compound catabolic process	GO:0019439	286	0.011
protein secretion	GO:0009306	111	0.011
regulation of ion transport	GO:0043269	215	0.011
respiratory tube development	GO:0030323	167	0.011
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.011
organophosphate biosynthetic process	GO:0090407	122	0.011
cellular response to external stimulus	GO:0071496	88	0.011
nucleoside bisphosphate biosynthetic process	GO:0033866	6	0.011
protein modification by small protein conjugation or removal	GO:0070647	207	0.011
establishment or maintenance of cell polarity	GO:0007163	86	0.011
response to organonitrogen compound	GO:0010243	246	0.011
regulation of protein catabolic process	GO:0042176	108	0.011
p38mapk cascade	GO:0038066	4	0.011
positive regulation of phospholipase activity	GO:0010518	3	0.011
nucleoside metabolic process	GO:0009116	246	0.011
regulation of apoptotic signaling pathway	GO:2001233	197	0.011
negative regulation of protein modification process	GO:0031400	163	0.011
regulation of cytokine production	GO:0001817	266	0.011
cellular metal ion homeostasis	GO:0006875	151	0.011
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.011
regulation of cell morphogenesis involved in differentiation	GO:0010769	151	0.011
purine ribonucleotide metabolic process	GO:0009150	290	0.011
regulation of mapk cascade	GO:0043408	248	0.011
fatty acid metabolic process	GO:0006631	121	0.011
organophosphate ester transport	GO:0015748	28	0.011
regulation of cell activation	GO:0050865	289	0.011
regulation of proteolysis	GO:0030162	164	0.010
sequestering of calcium ion	GO:0051208	18	0.010
ribose phosphate biosynthetic process	GO:0046390	59	0.010
histone modification	GO:0016570	159	0.010
regulation of cellular response to stress	GO:0080135	159	0.010
response to cholesterol	GO:0070723	4	0.010
hormone secretion	GO:0046879	128	0.010
angiogenesis	GO:0001525	201	0.010
phosphatidylethanolamine biosynthetic process	GO:0006646	2	0.010
spermatid development	GO:0007286	108	0.010
regulation of transmembrane transport	GO:0034762	128	0.010
learning or memory	GO:0007611	148	0.010
regulation of protein localization	GO:0032880	231	0.010
response to inorganic substance	GO:0010035	96	0.010
heterocycle catabolic process	GO:0046700	280	0.010
nucleoside catabolic process	GO:0009164	206	0.010
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.010
establishment or maintenance of apical basal cell polarity	GO:0035088	21	0.010
eye pigmentation	GO:0048069	3	0.010
organism emergence from protective structure	GO:0071684	4	0.010
interleukin 8 secretion	GO:0072606	3	0.010
regulation of cell migration	GO:0030334	219	0.010
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.010

Sc4mol disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.084
inherited metabolic disorder	DOID:655	0.084
disease of cellular proliferation	DOID:14566	0.022
disease of mental health	DOID:150	0.022
developmental disorder of mental health	DOID:0060037	0.022
specific developmental disorder	DOID:0060038	0.022
non syndromic intellectual disability	DOID:0050889	0.022
intellectual disability	DOID:1059	0.022
nervous system disease	DOID:863	0.021
disease of anatomical entity	DOID:7	0.021
cancer	DOID:162	0.018
lipid metabolism disorder	DOID:3146	0.015
connective tissue disease	DOID:65	0.011
bone development disease	DOID:0080006	0.011
bone disease	DOID:0080001	0.011
musculoskeletal system disease	DOID:17	0.011

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