| positive regulation of apoptotic process | GO:0043065 | 217 | 0.184 | |
| synaptic transmission | GO:0007268 | 329 | 0.149 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.144 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.135 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.133 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.107 | |
| muscle tissue development | GO:0060537 | 308 | 0.090 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.080 | |
| macromolecule methylation | GO:0043414 | 120 | 0.079 | |
| methylation | GO:0032259 | 134 | 0.073 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.070 | |
| response to oxidative stress | GO:0006979 | 123 | 0.069 | |
| cell cycle checkpoint | GO:0000075 | 47 | 0.069 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.067 | |
| protein alkylation | GO:0008213 | 81 | 0.064 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 40 | 0.062 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.061 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.058 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.056 | |
| positive regulation of transcription elongation from rna polymerase ii promoter | GO:0032968 | 2 | 0.048 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.048 | |
| adaptive immune response | GO:0002250 | 155 | 0.048 | |
| organophosphate biosynthetic process | GO:0090407 | 122 | 0.045 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.044 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.043 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.043 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.043 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.042 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.041 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.041 | |
| glucose homeostasis | GO:0042593 | 128 | 0.040 | Mouse |
| negative regulation of mitotic cell cycle | GO:0045930 | 58 | 0.040 | |
| regulation of zinc ion transport | GO:0071579 | 2 | 0.040 | |
| protein methylation | GO:0006479 | 81 | 0.039 | |
| fat cell differentiation | GO:0045444 | 160 | 0.039 | |
| gene silencing | GO:0016458 | 38 | 0.039 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.038 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.038 | |
| chromatin modification | GO:0016568 | 187 | 0.037 | |
| multicellular organism growth | GO:0035264 | 161 | 0.036 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.035 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.034 | |
| stem cell development | GO:0048864 | 219 | 0.033 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.033 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.033 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.032 | |
| neurotransmitter secretion | GO:0007269 | 62 | 0.032 | |
| stem cell maintenance | GO:0019827 | 130 | 0.031 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.031 | |
| regulation of synaptic plasticity | GO:0048167 | 87 | 0.031 | |
| positive regulation of dna templated transcription elongation | GO:0032786 | 2 | 0.031 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.031 | |
| regulation of glucose metabolic process | GO:0010906 | 60 | 0.030 | |
| response to inorganic substance | GO:0010035 | 96 | 0.030 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.029 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.029 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.029 | |
| dna metabolic process | GO:0006259 | 303 | 0.029 | |
| generation of precursor metabolites and energy | GO:0006091 | 103 | 0.028 | |
| glycogen metabolic process | GO:0005977 | 32 | 0.028 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.027 | Mouse |
| mitotic cell cycle | GO:0000278 | 195 | 0.027 | |
| stem cell differentiation | GO:0048863 | 268 | 0.027 | |
| lipid phosphorylation | GO:0046834 | 25 | 0.027 | |
| oxidation reduction process | GO:0055114 | 342 | 0.026 | |
| neuron death | GO:0070997 | 154 | 0.026 | |
| skeletal muscle organ development | GO:0060538 | 163 | 0.026 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 95 | 0.026 | |
| carbohydrate biosynthetic process | GO:0016051 | 74 | 0.026 | |
| muscle cell development | GO:0055001 | 133 | 0.026 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.025 | |
| neuron apoptotic process | GO:0051402 | 142 | 0.025 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.025 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.025 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 126 | 0.025 | |
| regulation of carbohydrate biosynthetic process | GO:0043255 | 40 | 0.025 | |
| long term synaptic potentiation | GO:0060291 | 25 | 0.024 | |
| cellular carbohydrate metabolic process | GO:0044262 | 119 | 0.024 | |
| rhythmic process | GO:0048511 | 174 | 0.024 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 45 | 0.024 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.024 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.024 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.023 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.023 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.023 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.023 | |
| signal transduction by p53 class mediator | GO:0072331 | 51 | 0.023 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.023 | |
| cell cycle g1 s phase transition | GO:0044843 | 57 | 0.023 | |
| regulation of histone modification | GO:0031056 | 56 | 0.023 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.022 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.022 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.022 | |
| regulation of secretion | GO:0051046 | 274 | 0.022 | |
| negative regulation of protein maturation | GO:1903318 | 79 | 0.022 | |
| cation transport | GO:0006812 | 399 | 0.022 | |
| histone modification | GO:0016570 | 159 | 0.022 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.021 | |
| phosphatidylinositol phosphorylation | GO:0046854 | 23 | 0.021 | |
| mitochondrion organization | GO:0007005 | 134 | 0.021 | |
| regulation of myeloid cell differentiation | GO:0045637 | 96 | 0.021 | |
| digestive tract development | GO:0048565 | 190 | 0.021 | |
| amine metabolic process | GO:0009308 | 45 | 0.021 | |
| response to peptide hormone | GO:0043434 | 127 | 0.021 | Mouse |
| lipid biosynthetic process | GO:0008610 | 179 | 0.021 | |
| vesicle localization | GO:0051648 | 86 | 0.020 | |
| myeloid leukocyte differentiation | GO:0002573 | 119 | 0.020 | |
| response to radiation | GO:0009314 | 165 | 0.020 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.020 | |
| blastocyst development | GO:0001824 | 80 | 0.020 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.020 | |
| pyruvate metabolic process | GO:0006090 | 28 | 0.020 | |
| carbohydrate catabolic process | GO:0016052 | 32 | 0.020 | |
| protein processing | GO:0016485 | 163 | 0.019 | |
| ossification | GO:0001503 | 216 | 0.019 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.019 | |
| regulation of lipid metabolic process | GO:0019216 | 118 | 0.019 | |
| glucan metabolic process | GO:0044042 | 32 | 0.019 | |
| intrinsic apoptotic signaling pathway in response to dna damage | GO:0008630 | 57 | 0.019 | |
| protein localization to chromatin | GO:0071168 | 3 | 0.019 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 61 | 0.019 | |
| regulation of myeloid leukocyte differentiation | GO:0002761 | 58 | 0.019 | |
| regulation of cell migration | GO:0030334 | 219 | 0.019 | |
| polysaccharide metabolic process | GO:0005976 | 39 | 0.019 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.019 | |
| cytokine production | GO:0001816 | 319 | 0.019 | |
| regulation of g protein coupled receptor protein signaling pathway | GO:0008277 | 37 | 0.019 | |
| skeletal muscle cell differentiation | GO:0035914 | 66 | 0.019 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.018 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.018 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.018 | |
| response to light stimulus | GO:0009416 | 135 | 0.018 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.018 | |
| nuclear transcribed mrna catabolic process nonsense mediated decay | GO:0000184 | 1 | 0.018 | |
| regulation of transmembrane transport | GO:0034762 | 128 | 0.018 | |
| smoothened signaling pathway | GO:0007224 | 105 | 0.018 | |
| male gamete generation | GO:0048232 | 285 | 0.017 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.017 | |
| dna recombination | GO:0006310 | 92 | 0.017 | |
| signal transduction in absence of ligand | GO:0038034 | 55 | 0.017 | |
| chromatin silencing | GO:0006342 | 15 | 0.017 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.017 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.017 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.016 | |
| response to insulin | GO:0032868 | 100 | 0.016 | Mouse |
| regulation of feeding behavior | GO:0060259 | 3 | 0.016 | |
| glucose metabolic process | GO:0006006 | 92 | 0.016 | |
| circadian rhythm | GO:0007623 | 114 | 0.016 | |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.016 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.016 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.016 | |
| mitochondrial genome maintenance | GO:0000002 | 15 | 0.016 | |
| positive regulation of growth | GO:0045927 | 104 | 0.016 | |
| negative regulation of cell cycle process | GO:0010948 | 69 | 0.016 | |
| t cell activation | GO:0042110 | 289 | 0.016 | |
| cellular response to peptide hormone stimulus | GO:0071375 | 92 | 0.016 | |
| regulation of ion transmembrane transport | GO:0034765 | 119 | 0.016 | |
| digestive tract morphogenesis | GO:0048546 | 147 | 0.016 | |
| regulation of chromatin silencing | GO:0031935 | 2 | 0.016 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.016 | |
| transmembrane transport | GO:0055085 | 412 | 0.016 | |
| nuclear division | GO:0000280 | 158 | 0.016 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.016 | |
| nucleotide biosynthetic process | GO:0009165 | 78 | 0.016 | |
| histone lysine demethylation | GO:0070076 | 13 | 0.015 | |
| mitotic cell cycle checkpoint | GO:0007093 | 31 | 0.015 | |
| peptidyl serine modification | GO:0018209 | 83 | 0.015 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.015 | |
| microtubule based process | GO:0007017 | 236 | 0.015 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.015 | |
| membrane organization | GO:0061024 | 245 | 0.015 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 73 | 0.015 | |
| regulation of binding | GO:0051098 | 111 | 0.015 | |
| regulation of postsynaptic membrane potential | GO:0060078 | 48 | 0.015 | |
| maintenance of location | GO:0051235 | 89 | 0.015 | |
| digestive system development | GO:0055123 | 200 | 0.015 | |
| establishment of protein localization to membrane | GO:0090150 | 54 | 0.015 | |
| hexose metabolic process | GO:0019318 | 98 | 0.015 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.015 | |
| dna endoreduplication | GO:0042023 | 4 | 0.015 | |
| cell division | GO:0051301 | 120 | 0.015 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.015 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 57 | 0.014 | |
| glycerophospholipid biosynthetic process | GO:0046474 | 32 | 0.014 | |
| regulation of cell activation | GO:0050865 | 289 | 0.014 | |
| defense response to bacterium | GO:0042742 | 119 | 0.014 | |
| negative regulation of organelle organization | GO:0010639 | 90 | 0.014 | |
| dna repair | GO:0006281 | 107 | 0.014 | |
| chromatin organization | GO:0006325 | 206 | 0.014 | |
| response to nutrient levels | GO:0031667 | 109 | 0.014 | |
| organelle localization | GO:0051640 | 179 | 0.014 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.014 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.014 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.014 | |
| sensory perception of sound | GO:0007605 | 97 | 0.014 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.014 | |
| positive regulation of defense response | GO:0031349 | 124 | 0.014 | |
| phospholipid metabolic process | GO:0006644 | 87 | 0.014 | |
| glucocorticoid mediated signaling pathway | GO:0043402 | 3 | 0.014 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 48 | 0.013 | |
| regulation of neuron apoptotic process | GO:0043523 | 122 | 0.013 | |
| cell adhesion | GO:0007155 | 329 | 0.013 | |
| establishment of vesicle localization | GO:0051650 | 81 | 0.013 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.013 | |
| developmental maturation | GO:0021700 | 193 | 0.013 | |
| multi multicellular organism process | GO:0044706 | 109 | 0.013 | |
| cytokine mediated signaling pathway | GO:0019221 | 115 | 0.013 | |
| regulation of protein processing | GO:0070613 | 96 | 0.013 | |
| neurotransmitter transport | GO:0006836 | 76 | 0.013 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.013 | |
| multicellular organismal signaling | GO:0035637 | 91 | 0.013 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.013 | |
| mitotic sister chromatid cohesion | GO:0007064 | 1 | 0.013 | |
| regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002822 | 87 | 0.013 | |
| regulation of cellular carbohydrate metabolic process | GO:0010675 | 75 | 0.013 | |
| dna damage checkpoint | GO:0000077 | 26 | 0.013 | |
| histone lysine methylation | GO:0034968 | 50 | 0.013 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.013 | |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.013 | |
| spermatid differentiation | GO:0048515 | 115 | 0.013 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 112 | 0.012 | |
| cellular response to abiotic stimulus | GO:0071214 | 56 | 0.012 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.012 | Mouse |
| mapk cascade | GO:0000165 | 281 | 0.012 | |
| monosaccharide biosynthetic process | GO:0046364 | 44 | 0.012 | |
| phospholipid biosynthetic process | GO:0008654 | 36 | 0.012 | |
| b cell activation | GO:0042113 | 161 | 0.012 | |
| cellular response to lipid | GO:0071396 | 145 | 0.012 | |
| canonical wnt signaling pathway | GO:0060070 | 130 | 0.012 | |
| spermatogenesis | GO:0007283 | 284 | 0.012 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.012 | |
| regulation of protein maturation | GO:1903317 | 96 | 0.012 | |
| leukocyte proliferation | GO:0070661 | 172 | 0.012 | |
| response to peptide | GO:1901652 | 136 | 0.012 | Mouse |
| regulation of fat cell differentiation | GO:0045598 | 81 | 0.012 | |
| myosin filament assembly | GO:0031034 | 2 | 0.012 | |
| cardiac muscle contraction | GO:0060048 | 32 | 0.012 | |
| energy derivation by oxidation of organic compounds | GO:0015980 | 77 | 0.012 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.012 | |
| histone h4 k16 acetylation | GO:0043984 | 3 | 0.012 | |
| hexose biosynthetic process | GO:0019319 | 39 | 0.012 | |
| regulation of protein binding | GO:0043393 | 60 | 0.012 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.012 | |
| mrna catabolic process | GO:0006402 | 22 | 0.012 | |
| protein ubiquitination | GO:0016567 | 171 | 0.012 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.012 | |
| small molecule catabolic process | GO:0044282 | 71 | 0.012 | |
| nucleoside phosphate biosynthetic process | GO:1901293 | 79 | 0.012 | |
| protein maturation | GO:0051604 | 176 | 0.012 | |
| glycerophospholipid metabolic process | GO:0006650 | 71 | 0.012 | |
| positive regulation of myeloid cell apoptotic process | GO:0033034 | 4 | 0.011 | |
| dendrite development | GO:0016358 | 115 | 0.011 | |
| dna integrity checkpoint | GO:0031570 | 28 | 0.011 | |
| rna catabolic process | GO:0006401 | 29 | 0.011 | |
| retrograde transport endosome to golgi | GO:0042147 | 2 | 0.011 | |
| protein autophosphorylation | GO:0046777 | 61 | 0.011 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.011 | |
| monocarboxylic acid metabolic process | GO:0032787 | 191 | 0.011 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.011 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.011 | |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.011 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.011 | |
| regulation of peptidase activity | GO:0052547 | 96 | 0.011 | |
| myosin filament organization | GO:0031033 | 3 | 0.011 | |
| positive regulation of fibroblast growth factor receptor signaling pathway | GO:0045743 | 3 | 0.011 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.011 | |
| peptidyl tyrosine modification | GO:0018212 | 145 | 0.011 | |
| negative regulation of glycoprotein metabolic process | GO:1903019 | 3 | 0.011 | |
| glycolytic process | GO:0006096 | 20 | 0.011 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.011 | |
| compound eye development | GO:0048749 | 1 | 0.011 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.011 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.011 | |
| organelle fission | GO:0048285 | 170 | 0.011 | |
| phosphatidylinositol biosynthetic process | GO:0006661 | 15 | 0.011 | |
| cardiac muscle cell differentiation | GO:0055007 | 69 | 0.011 | |
| substantia nigra development | GO:0021762 | 2 | 0.011 | |
| regulation of cell cycle phase transition | GO:1901987 | 77 | 0.011 | |
| sensory perception | GO:0007600 | 245 | 0.011 | |
| purine nucleotide biosynthetic process | GO:0006164 | 65 | 0.011 | |
| regulation of protein transport | GO:0051223 | 163 | 0.011 | |
| intrinsic apoptotic signaling pathway by p53 class mediator | GO:0072332 | 35 | 0.011 | |
| circulatory system process | GO:0003013 | 197 | 0.011 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.011 | |
| divalent inorganic cation homeostasis | GO:0072507 | 138 | 0.010 | |
| response to acid chemical | GO:0001101 | 111 | 0.010 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.010 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.010 | |
| cellular response to lipopolysaccharide | GO:0071222 | 77 | 0.010 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.010 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.010 | |
| regionalization | GO:0003002 | 337 | 0.010 | |
| cohesin localization to chromatin | GO:0071921 | 1 | 0.010 | |
| protein acylation | GO:0043543 | 64 | 0.010 | |
| response to reactive oxygen species | GO:0000302 | 56 | 0.010 | |
| germ cell development | GO:0007281 | 185 | 0.010 | |
| cellular response to external stimulus | GO:0071496 | 88 | 0.010 | |