Mus musculus

119 known processes

Shc1

src homology 2 domain-containing transforming protein C1

(Aliases: p66shc,Shc,ShcA,p66)

Shc1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of mapk cascadeGO:00434082480.995
platelet derived growth factor receptor signaling pathwayGO:0048008320.993
ras protein signal transductionGO:0007265770.992
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.986
fibroblast growth factor receptor signaling pathwayGO:0008543460.951
negative regulation of cellular amine metabolic processGO:003323910.947
response to oxidative stressGO:00069791230.947
Rat
leukocyte differentiationGO:00025213420.944
positive regulation of kinase activityGO:00336741550.906
myeloid cell differentiationGO:00300992330.901
negative regulation of peptidyl tyrosine phosphorylationGO:0050732170.892
negative regulation of cellular amino acid metabolic processGO:004576300.879
epidermal growth factor receptor signaling pathwayGO:0007173280.873
cellular response to fibroblast growth factor stimulusGO:0044344470.850
rho protein signal transductionGO:0007266320.832
regulation of ras gtpase activityGO:0032318880.827
endocytosisGO:00068971680.824
positive regulation of mapk cascadeGO:00434101700.819
cytoplasmic transportGO:00164822340.816
actin cytoskeleton organizationGO:00300362200.798
myeloid leukocyte differentiationGO:00025731190.780
negative regulation of granulocyte differentiationGO:003085330.780
regulation of mast cell activationGO:0033003210.770
negative regulation of phosphorylationGO:00423261660.769
regulation of b cell differentiationGO:0045577230.766
amine metabolic processGO:0009308450.759
regulation of rho gtpase activityGO:0032319580.758
small gtpase mediated signal transductionGO:0007264970.757
negative regulation of receptor activityGO:200027250.721
regulation of transferase activityGO:00513382630.720
regulation of ras protein signal transductionGO:00465781140.717
regulation of map kinase activityGO:00434051200.714
positive regulation of intracellular transportGO:0032388700.701
alcohol catabolic processGO:0046164160.700
regulation of antigen receptor mediated signaling pathwayGO:0050854290.692
positive regulation of rac gtpase activityGO:0032855140.683
negative regulation of cell activationGO:00508661110.681
osteoclast differentiationGO:0030316620.678
regulation of vesicle mediated transportGO:00606271390.674
positive regulation of rho gtpase activityGO:0032321410.670
regulation of lymphocyte differentiationGO:00456191070.666
lysosome localizationGO:0032418200.652
developmental growth involved in morphogenesisGO:00605601380.646
phosphatidylinositol metabolic processGO:0046488450.643
response to fibroblast growth factorGO:0071774470.637
regulation of anatomical structure sizeGO:00900661780.631
Rat
negative regulation of phosphorus metabolic processGO:00105631840.625
positive regulation of leukocyte mediated immunityGO:0002705700.623
regulation of kinase activityGO:00435492490.617
mitochondrion distributionGO:004831140.616
response to organonitrogen compoundGO:00102432460.616
Rat
negative regulation of protein tyrosine kinase activityGO:006109930.614
regulation of cellular response to stressGO:00801351590.604
lipid storageGO:0019915360.601
response to growth factorGO:00708481980.600
synaptic vesicle recyclingGO:0036465190.589
erbb signaling pathwayGO:0038127320.573
negative regulation of epidermal growth factor activated receptor activityGO:000717530.556
regulation of protein kinase activityGO:00458592320.554
guanosine containing compound metabolic processGO:19010681440.537
regulation of mast cell activation involved in immune responseGO:0033006170.526
mapk cascadeGO:00001652810.525
regulation of epidermal growth factor activated receptor activityGO:000717670.523
gland developmentGO:00487323300.517
muscle cell differentiationGO:00426922610.515
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.504
regulation of intracellular transportGO:00323861590.500
regenerationGO:0031099380.499
Rat
glycerophospholipid metabolic processGO:0006650710.496
labyrinthine layer developmentGO:0060711490.493
positive regulation of leukocyte differentiationGO:1902107860.484
peptidyl serine modificationGO:0018209830.478
negative regulation of protein phosphorylationGO:00019331260.476
lens development in camera type eyeGO:0002088620.476
urogenital system developmentGO:00016552610.470
cellular response to peptideGO:1901653920.467
Rat
cellular response to growth factor stimulusGO:00713631970.459
regulation of t cell activationGO:00508631700.451
response to peptide hormoneGO:00434341270.444
Rat
dephosphorylationGO:00163111290.438
organophosphate catabolic processGO:00464342320.433
organic hydroxy compound catabolic processGO:1901616250.412
regulation of cell activationGO:00508652890.406
leukocyte proliferationGO:00706611720.405
negative regulation of map kinase activityGO:0043407340.404
ribonucleoside triphosphate catabolic processGO:00092031990.398
immune response activating cell surface receptor signaling pathwayGO:0002429720.391
b cell differentiationGO:0030183780.389
phospholipid dephosphorylationGO:004683960.387
cell cycle g1 s phase transitionGO:0044843570.381
regulation of proteolysisGO:00301621640.381
regulation of leukocyte mediated immunityGO:00027031040.378
peptidyl threonine phosphorylationGO:0018107310.373
intracellular distribution of mitochondriaGO:004831210.371
ribonucleotide metabolic processGO:00092592910.369
positive regulation of protein modification processGO:00314012990.368
homeostasis of number of cellsGO:00488722100.367
terminal button organizationGO:007255330.362
t cell receptor signaling pathwayGO:0050852460.360
germ cell developmentGO:00072811850.357
organelle localizationGO:00516401790.357
regulation of lymphocyte proliferationGO:00506701170.357
activation of rac gtpase activityGO:003286320.350
negative regulation of phosphate metabolic processGO:00459361840.349
positive regulation of apoptotic processGO:00430652170.349
organic cyclic compound catabolic processGO:19013612950.347
t cell proliferationGO:00420981200.346
inositol phosphate catabolic processGO:007154540.344
organ regenerationGO:003110020.342
Rat
synaptic transmissionGO:00072683290.340
Mouse
small molecule catabolic processGO:0044282710.336
positive regulation of map kinase activityGO:0043406840.327
axonogenesisGO:00074092740.326
olfactory learningGO:000835520.326
regulation of cellular amine metabolic processGO:0033238200.321
regulation of mitotic cell cycleGO:00073461260.321
regulation of cellular catabolic processGO:00313292420.320
protein localization to nucleusGO:00345041210.319
regulation of protein tyrosine kinase activityGO:0061097170.318
cytokine mediated signaling pathwayGO:00192211150.315
cytokine productionGO:00018163190.310
regionalizationGO:00030023370.308
regulation of insulin receptor signaling pathwayGO:0046626210.305
skeletal system morphogenesisGO:00487052030.305
t cell tolerance inductionGO:000251760.300
synaptic vesicle localizationGO:0097479590.298
negative regulation of mapk cascadeGO:0043409650.297
mitotic cell cycleGO:00002781950.296
regulation of actin cytoskeleton organizationGO:0032956840.295
rac protein signal transductionGO:0016601130.293
cellular response to organonitrogen compoundGO:00714171450.292
Rat
humoral immune responseGO:0006959570.291
regulation of cell cycleGO:00517262810.291
positive regulation of protein catabolic processGO:0045732600.290
lymphocyte proliferationGO:00466511640.290
apoptotic signaling pathwayGO:00971903060.287
negative regulation of erbb signaling pathwayGO:190118570.286
positive regulation of myeloid leukocyte mediated immunityGO:0002888140.284
photoreceptor cell differentiationGO:0046530520.283
ribonucleoside catabolic processGO:00424542060.281
erk1 and erk2 cascadeGO:0070371770.280
calcium ion transport into cytosolGO:0060402480.276
neural precursor cell proliferationGO:00613511210.276
cell type specific apoptotic processGO:00972852680.275
nucleoside metabolic processGO:00091162460.275
blood vessel morphogenesisGO:00485142850.274
negative regulation of epidermal growth factor receptor signaling pathwayGO:004205960.271
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.271
protein catabolic processGO:00301632210.271
positive regulation of gtpase activityGO:0043547850.268
immune effector processGO:00022523210.265
Fly
regulation of protein serine threonine kinase activityGO:00719001570.265
myotube differentiationGO:00149021050.264
positive regulation of protein phosphorylationGO:00019342420.254
response to peptideGO:19016521360.252
Rat
glycerolipid biosynthetic processGO:0045017500.252
monocyte differentiationGO:003022490.252
cellular ketone metabolic processGO:0042180840.251
positive regulation of t cell tolerance inductionGO:000266660.251
synaptic vesicle transportGO:0048489570.248
fused antrum stageGO:004816510.246
forebrain developmentGO:00309003020.244
positive regulation of cell deathGO:00109422240.240
protein kinase b signalingGO:0043491740.239
embryonic placenta developmentGO:0001892980.239
negative regulation of cellular protein metabolic processGO:00322692470.238
positive regulation of apoptotic signaling pathwayGO:2001235950.235
regulation of rho protein signal transductionGO:0035023710.234
neuron projection extensionGO:1990138640.234
nucleotide catabolic processGO:00091662170.233
peptidyl amino acid modificationGO:00181933360.233
cell cell signaling involved in cell fate commitmentGO:0045168350.231
intracellular protein transportGO:00068862040.231
myeloid leukocyte activationGO:0002274830.229
nucleotide metabolic processGO:00091173320.228
phosphorylated carbohydrate dephosphorylationGO:004683840.228
positive regulation of transferase activityGO:00513471670.228
positive regulation of cell migrationGO:00303351090.224
release of sequestered calcium ion into cytosolGO:0051209420.222
positive regulation of protein kinase b signalingGO:0051897320.221
neutrophil differentiationGO:003022330.220
guanosine containing compound catabolic processGO:19010691440.219
activation of mapk activityGO:0000187590.218
regulation of lung blood pressureGO:001491620.218
nucleoside catabolic processGO:00091642060.215
purine nucleotide catabolic processGO:00061952110.215
regulation of receptor activityGO:0010469410.213
regulation of ion transportGO:00432692150.211
macromolecule catabolic processGO:00090572810.210
establishment of organelle localizationGO:00516561220.210
regulation of cell cycle processGO:00105641600.209
actin filament organizationGO:00070151130.209
regulation of leukocyte differentiationGO:19021051590.208
lymphocyte differentiationGO:00300982420.206
t cell activationGO:00421102890.204
t cell anergyGO:000287040.203
nucleoside phosphate metabolic processGO:00067533380.202
positive regulation of cytoplasmic transportGO:1903651400.200
positive regulation of tolerance inductionGO:000264580.197
purine ribonucleoside triphosphate metabolic processGO:00092052200.197
digestive system developmentGO:00551232000.197
sensory organ morphogenesisGO:00905962420.196
insulin receptor signaling pathwayGO:0008286490.191
Rat
regulation of jun kinase activityGO:0043506400.190
positive regulation of jun kinase activityGO:0043507300.190
regulation of homeostatic processGO:00328441820.190
regulation of organelle organizationGO:00330432890.189
regulation of tolerance induction to self antigenGO:000264910.188
negative regulation of immune system processGO:00026832090.187
regulation of cellular senescenceGO:200077260.186
skin developmentGO:00435882200.185
cellular amino acid metabolic processGO:00065201030.184
lateral inhibitionGO:004633110.184
protein targetingGO:00066051430.181
positive regulation of ras gtpase activityGO:0032320650.179
myeloid cell homeostasisGO:00022621140.178
vesicle localizationGO:0051648860.178
regulation of actin filament based processGO:0032970990.173
negative regulation of bone remodelingGO:004685160.172
regulation of cell migrationGO:00303342190.168
cell activation involved in immune responseGO:00022631260.167
regulation of autophagyGO:0010506300.166
establishment of vesicle localizationGO:0051650810.165
stress activated protein kinase signaling cascadeGO:0031098810.163
modification dependent protein catabolic processGO:00199411330.163
positive regulation of t cell differentiationGO:0045582520.163
regulation of lymphocyte activationGO:00512492400.159
skeletal system developmentGO:00015013560.159
organonitrogen compound catabolic processGO:19015652640.158
regulation of jnk cascadeGO:0046328620.158
regulation of t cell differentiationGO:0045580830.157
t cell differentiationGO:00302171740.157
purine nucleoside triphosphate metabolic processGO:00091442260.155
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.155
transmembrane transportGO:00550854120.155
activation of jun kinase activityGO:0007257150.155
positive regulation of cell activationGO:00508671580.154
regulation of cytoskeleton organizationGO:00514931220.153
gtp catabolic processGO:00061841430.153
immune response activating signal transductionGO:00027571160.153
endomembrane system organizationGO:00102561470.153
regulation of cell motilityGO:20001452360.152
regulation of epithelial cell proliferationGO:00506781410.152
male sex differentiationGO:00466611090.151
glycosyl compound metabolic processGO:19016572460.151
cellular component assembly involved in morphogenesisGO:00109271390.150
negative regulation of b cell receptor signaling pathwayGO:005085940.149
gtp metabolic processGO:00460391440.149
regulation of apoptotic signaling pathwayGO:20012331970.148
regulation of mast cell degranulationGO:0043304160.148
mast cell degranulationGO:0043303190.147
nucleoside phosphate catabolic processGO:19012922220.147
embryonic organ morphogenesisGO:00485622760.147
gastrulationGO:00073691160.146
cellular nitrogen compound catabolic processGO:00442702800.146
regulation of cellular amino acid metabolic processGO:000652150.145
negative regulation of osteoclast differentiationGO:0045671120.145
regulation of cell projection organizationGO:00313442060.144
maintenance of locationGO:0051235890.144
stress activated mapk cascadeGO:0051403800.143
regulation of terminal button organizationGO:200033110.142
growth plate cartilage chondrocyte growthGO:000343020.142
b cell proliferationGO:0042100530.138
wnt signaling pathwayGO:00160551880.138
negative regulation of leukocyte proliferationGO:0070664460.137
jnk cascadeGO:0007254720.136
neuroblast proliferationGO:0007405490.136
positive regulation of cellular catabolic processGO:00313311480.136
autophagyGO:0006914450.133
regulation of nucleoside metabolic processGO:00091181300.133
tissue remodelingGO:00487711020.132
spermatid developmentGO:00072861080.132
axon extension involved in axon guidanceGO:0048846140.132
lens fiber cell apoptotic processGO:199008640.132
lipid localizationGO:00108761260.131
response to uvGO:0009411440.131
gastrulation with mouth forming secondGO:0001702290.130
negative regulation of kinase activityGO:0033673810.130
ion transmembrane transportGO:00342203610.127
protein localization to organelleGO:00333651850.126
dendritic spine organizationGO:0097061260.126
regulation of membrane potentialGO:00423911920.126
positive regulation of leukocyte degranulationGO:0043302100.125
regulation of hydrolase activityGO:00513362460.124
positive regulation of cellular amino acid metabolic processGO:004576430.123
single organismal cell cell adhesionGO:00163371310.122
ribonucleoside triphosphate metabolic processGO:00091992200.120
positive regulation of mast cell degranulationGO:0043306100.119
placenta developmentGO:00018901400.119
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.118
proteolysis involved in cellular protein catabolic processGO:00516031470.117
regulation of tolerance inductionGO:0002643100.117
negative regulation of protein modification processGO:00314001630.116
positive regulation of protein serine threonine kinase activityGO:00719021060.116
tissue regenerationGO:0042246220.115
positive regulation of stress activated mapk cascadeGO:0032874480.114
regulation of erythrocyte differentiationGO:0045646230.114
regulation of myeloid leukocyte differentiationGO:0002761580.113
protein import into nucleusGO:0006606950.112
optic placode formationGO:000174320.112
immune response regulating cell surface receptor signaling pathwayGO:0002768800.112
positive regulation of protein kinase activityGO:00458601440.111
spermatid differentiationGO:00485151150.110
regulation of cytoplasmic transportGO:19036491120.110
ribose phosphate metabolic processGO:00196932910.110
ruffle organizationGO:0031529160.108
canonical wnt signaling pathwayGO:00600701300.108
positive regulation of b cell differentiationGO:0045579130.108
regulation of t cell proliferationGO:0042129920.107
response to endoplasmic reticulum stressGO:0034976530.107
Worm
response to sterolGO:003631440.106
regulation of nucleotide catabolic processGO:00308111220.106
compound eye developmentGO:004874910.105
regulation of cellular component biogenesisGO:00440871810.105
angiogenesisGO:00015252010.105
stem cell developmentGO:00488642190.101
lateral mesoderm morphogenesisGO:004836930.101
epidermis developmentGO:00085441870.101
regulation of dendritic spine morphogenesisGO:0061001170.100
female sex differentiationGO:0046660840.099
negative regulation of intracellular signal transductionGO:19025321670.098
regulation of lymphocyte anergyGO:000291140.098
cell chemotaxisGO:0060326810.097
regulation of leukocyte proliferationGO:00706631210.097
protein ubiquitinationGO:00165671710.097
positive regulation of lymphocyte anergyGO:000291340.097
neuron projection extension involved in neuron projection guidanceGO:1902284140.096
positive regulation of myeloid cell differentiationGO:0045639430.096
gonad developmentGO:00084061410.095
purine ribonucleotide catabolic processGO:00091542080.095
photoreceptor cell developmentGO:0042461400.094
positive regulation of gtp catabolic processGO:0033126850.094
locomotory behaviorGO:00076261950.094
regulation of osteoclast differentiationGO:0045670360.094
purine nucleoside catabolic processGO:00061522050.094
cell agingGO:0007569350.094
synaptic vesicle endocytosisGO:0048488190.093
cellular response to epidermal growth factor stimulusGO:007136440.093
actin filament polymerizationGO:0030041440.093
positive regulation of immune effector processGO:00026991070.092
regulation of smad protein import into nucleusGO:006039030.092
determination of adult lifespanGO:0008340110.092
axon guidanceGO:00074111410.091
inositol lipid mediated signalingGO:0048017410.091
digestive tract morphogenesisGO:00485461470.090
single organism cell adhesionGO:00986021560.089
bone resorptionGO:0045453380.089
neural plate mediolateral regionalizationGO:002199810.088
purine nucleoside metabolic processGO:00422782410.088
regulation of endocytosisGO:0030100690.087
myeloid cell activation involved in immune responseGO:0002275340.087
single organism nuclear importGO:1902593950.086
bronchus morphogenesisGO:006043420.086
purine nucleotide metabolic processGO:00061633020.085
regulation of t cell tolerance inductionGO:000266460.084
protein importGO:00170381010.084
response to epidermal growth factorGO:007084940.082
multicellular organismal agingGO:0010259240.082
regulation of secretion by cellGO:19035302490.082
positive regulation of reactive oxygen species metabolic processGO:2000379110.081
purine ribonucleoside metabolic processGO:00461282410.081
positive regulation of programmed cell deathGO:00430682180.081
tor signalingGO:0031929210.081
Fly
cellular response to amino acid stimulusGO:0071230290.081
negative regulation of bone resorptionGO:004577960.081
negative regulation of homeostatic processGO:0032845710.080
positive regulation of b cell tolerance inductionGO:000266320.080
hexose metabolic processGO:0019318980.080
activation of immune responseGO:00022531380.079
regulation of cell projection assemblyGO:0060491380.078
regulation of t cell anergyGO:000266740.078
response to radiationGO:00093141650.078
positive regulation of smad protein import into nucleusGO:006039120.078
mitotic cell cycle processGO:19030471590.077
proteasomal protein catabolic processGO:0010498980.077
cellular response to insulin stimulusGO:0032869780.077
Rat
regulation of cellular ketone metabolic processGO:0010565660.077
response to cholesterolGO:007072340.076
cellular protein catabolic processGO:00442571550.076
camera type eye developmentGO:00430102660.076
mast cell activation involved in immune responseGO:0002279200.076
positive regulation of erythrocyte differentiationGO:0045648110.076
molting cycleGO:0042303900.076
positive regulation of lymphocyte differentiationGO:0045621610.075
phosphatidylinositol biosynthetic processGO:0006661150.075
bone morphogenesisGO:0060349780.075
positive regulation of protein import into nucleusGO:0042307260.075
negative regulation of cell developmentGO:00107211690.075
activation of mapkk activityGO:0000186150.075
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.075
negative regulation of antigen receptor mediated signaling pathwayGO:0050858160.075
regulation of protein catabolic processGO:00421761080.074
cell recognitionGO:0008037830.073
regulation of purine nucleotide catabolic processGO:00331211220.073
mammary gland morphogenesisGO:0060443540.073
response to calcium ionGO:0051592200.073
negative regulation of transferase activityGO:0051348850.072
modification dependent macromolecule catabolic processGO:00436321330.072
regulation of neuronal synaptic plasticityGO:0048168300.071
regulation of anti mullerian hormone signaling pathwayGO:190261210.071
regulation of stress activated mapk cascadeGO:0032872690.071
actin cytoskeleton reorganizationGO:0031532210.070
activation of ras gtpase activityGO:0032856110.069
regulation of cell adhesionGO:00301551540.069
macrophage differentiationGO:0030225200.069
morphogenesis of a branching structureGO:00017632030.069
stem cell maintenanceGO:00198271300.069
nucleoside triphosphate metabolic processGO:00091412300.069
regulated secretory pathwayGO:0045055320.067
organophosphate biosynthetic processGO:00904071220.067
leukocyte mediated immunityGO:00024431740.067
bone remodelingGO:0046849530.067
regulation of muscle tissue developmentGO:1901861970.067
inorganic ion transmembrane transportGO:00986602340.066
purine containing compound catabolic processGO:00725232130.066
epithelial tube morphogenesisGO:00605623030.066
cellular senescenceGO:0090398110.066
mitochondrion organizationGO:00070051340.065
regulation of epidermal growth factor receptor signaling pathwayGO:0042058130.065
positive regulation of t cell mediated cytotoxicityGO:0001916150.065
regulation of synaptic vesicle recyclingGO:190342120.065
dendritic spine developmentGO:0060996300.064
innate immune responseGO:00450871570.064
Fly
immunoglobulin mediated immune responseGO:0016064690.064
optic placode formation involved in camera type eye formationGO:004661920.064
positive regulation of cellular protein catabolic processGO:1903364340.064
mullerian duct regressionGO:000188010.064
regulation of purine nucleotide metabolic processGO:19005421690.063
cellular amine metabolic processGO:0044106440.062
membrane organizationGO:00610242450.062
circulatory system processGO:00030131970.062
Rat
insulin secretionGO:0030073890.062
inorganic cation transmembrane transportGO:00986622070.062
response to monosaccharideGO:0034284670.062
sequestering of metal ionGO:0051238190.062
glycerolipid metabolic processGO:00464861220.062
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434400.061
positive regulation of mitotic cell cycleGO:0045931410.061
lateral mesodermal cell differentiationGO:004837130.061
regulation of reactive oxygen species metabolic processGO:2000377400.060
positive regulation of proteolysisGO:0045862850.060
lymphocyte anergyGO:000224940.060
ruffle assemblyGO:0097178130.060
regulation of exocytosisGO:0017157610.060
carbohydrate metabolic processGO:00059752300.060
tolerance induction to self antigenGO:000251340.060
nucleobase containing small molecule metabolic processGO:00550863520.060
anti mullerian hormone signaling pathwayGO:199026210.059
positive regulation of nucleoside metabolic processGO:0045979910.059
negative regulation of molecular functionGO:00440922580.059
regulation of rac protein signal transductionGO:0035020190.059
cellular homeostasisGO:00197252400.058
maintenance of protein location in nucleusGO:005145720.058
actin polymerization or depolymerizationGO:0008154540.058
organelle assemblyGO:00709251770.058
endochondral bone morphogenesisGO:0060350500.058
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052310.058
regulation of cell sizeGO:0008361720.058
negative regulation of protein metabolic processGO:00512482820.057
peptidyl threonine modificationGO:0018210310.057
trivalent inorganic cation transportGO:007251250.057
positive regulation of skeletal muscle tissue regenerationGO:004341540.057
positive regulation of exocytosisGO:0045921200.057
negative regulation of ras protein signal transductionGO:0046580180.056
b cell tolerance inductionGO:000251420.056
fatty acid metabolic processGO:00066311210.056
negative regulation of lymphocyte activationGO:0051250910.055
regulation of neutrophil differentiationGO:004565820.055
regulation of excitatory postsynaptic membrane potentialGO:0060079410.055
spermatogenesisGO:00072832840.055
regulation of protein localizationGO:00328802310.055
g protein coupled receptor signaling pathwayGO:00071862430.055
branching morphogenesis of an epithelial tubeGO:00487541590.055
male gamete generationGO:00482322850.054
regulation of hormone levelsGO:00108172110.054
blastocyst developmentGO:0001824800.054
positive regulation of protein localization to nucleusGO:1900182300.054
positive regulation of cell cycleGO:0045787920.054
mitochondrion localizationGO:005164690.054
regulation of b cell tolerance inductionGO:000266120.053
engulfment of apoptotic cellGO:004365230.053
cellular response to cytokine stimulusGO:00713451890.053
regulation of erk1 and erk2 cascadeGO:0070372710.052
reactive oxygen species metabolic processGO:0072593840.052
regulation of embryonic developmentGO:0045995710.052
myosin filament assemblyGO:003103420.052
sulfur compound metabolic processGO:00067901000.052
renal system developmentGO:00720012250.052
exocytosisGO:00068871210.052
epithelial cell proliferationGO:00506731740.051

Shc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.222
disease of cellular proliferationDOID:1456600.222
organ system cancerDOID:005068600.142
gastrointestinal system cancerDOID:311900.061