Mus musculus

66 known processes

Six6

sine oculis-related homeobox 6 homolog (Drosophila)

(Aliases: Optx2,Six9)

Six6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transdifferentiationGO:006029010.911
ear morphogenesisGO:00424711180.890
Mouse
auditory receptor cell fate determinationGO:004266830.883
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic processGO:200076310.858
neuron fate specificationGO:0048665300.839
Mouse
forebrain developmentGO:00309003020.839
Mouse
central nervous system neuron developmentGO:0021954670.813
sensory organ morphogenesisGO:00905962420.804
Mouse Fly
positive regulation of inner ear receptor cell differentiationGO:200098210.798
telencephalon developmentGO:00215371860.795
Mouse
spermatogenesisGO:00072832840.789
Mouse
positive regulation of auditory receptor cell differentiationGO:004560910.772
phototransductionGO:0007602170.765
astrocyte fate commitmentGO:006001840.765
endocardial cushion to mesenchymal transition involved in heart valve formationGO:000319940.761
central nervous system neuron differentiationGO:00219531620.746
sensory perceptionGO:00076002450.693
Mouse
pancreatic a cell fate commitmentGO:000332620.680
neuron migrationGO:00017641220.679
hemangioblast cell differentiationGO:006021710.678
skeletal system morphogenesisGO:00487052030.674
Mouse
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formationGO:200080210.664
appendage developmentGO:00487361660.659
locomotory behaviorGO:00076261950.658
pancreatic pp cell fate commitmentGO:000332920.657
embryonic organ morphogenesisGO:00485622760.654
Mouse
cardiac neural crest cell migration involved in outflow tract morphogenesisGO:000325330.623
ear developmentGO:00435832000.613
Mouse
detection of light stimulusGO:0009583250.606
forebrain neuron developmentGO:0021884300.599
regulation of neuron differentiationGO:00456642810.596
Mouse
appendage morphogenesisGO:00351071490.589
semaphorin plexin signaling pathway involved in outflow tract morphogenesisGO:007152710.566
axonogenesisGO:00074092740.562
thyroid stimulating hormone secreting cell differentiationGO:006012940.560
paraxial mesodermal cell differentiationGO:004834220.559
ion transmembrane transportGO:00342203610.553
regionalizationGO:00030023370.552
Mouse
cell differentiation in spinal cordGO:0021515530.538
positive regulation of mechanoreceptor differentiationGO:004563310.533
circadian rhythmGO:00076231140.529
Mouse
auditory receptor cell fate specificationGO:004266710.523
somatotropin secreting cell differentiationGO:006012640.523
endocrine system developmentGO:0035270980.516
Mouse
pancreatic pp cell differentiationGO:000331220.513
g protein coupled receptor signaling pathwayGO:00071862430.507
skeletal system developmentGO:00015013560.507
Mouse
synaptic transmissionGO:00072683290.493
Mouse
regulation of endocardial cushion to mesenchymal transition involved in heart valve formationGO:200080010.491
visual perceptionGO:0007601520.488
inner ear morphogenesisGO:00424721010.482
Mouse
positive regulation of cell developmentGO:00107202370.481
diencephalon developmentGO:0021536630.472
Mouse
columnar cuboidal epithelial cell differentiationGO:0002065820.472
forebrain regionalizationGO:0021871250.468
Mouse
transmembrane transportGO:00550854120.464
circulatory system processGO:00030131970.461
embryonic appendage morphogenesisGO:00351131260.460
detection of stimulusGO:0051606840.458
regulation of cell morphogenesis involved in differentiationGO:00107691510.455
spinal cord developmentGO:0021510810.448
retina development in camera type eyeGO:00600411190.437
Mouse
inner ear receptor cell differentiationGO:0060113610.433
embryonic digit morphogenesisGO:0042733560.431
regulation of embryonic developmentGO:0045995710.427
Mouse
regulation of blood circulationGO:1903522930.411
negative regulation of oxidative phosphorylation uncoupler activityGO:200027620.407
forebrain neuron differentiationGO:0021879520.406
regulation of oxidative phosphorylation uncoupler activityGO:200027530.400
intracellular distribution of mitochondriaGO:004831210.395
paraxial mesodermal cell fate commitmentGO:004834320.392
limb developmentGO:00601731660.390
embryonic heart tube formationGO:000314410.389
nerve developmentGO:0021675670.387
Mouse
negative regulation of nervous system developmentGO:00519611560.387
Mouse
muscle tissue developmentGO:00605373080.383
Mouse
embryonic limb morphogenesisGO:00303261260.377
heart morphogenesisGO:00030071780.375
Mouse
regulation of organ formationGO:0003156340.373
Mouse
striated muscle tissue developmentGO:00147062930.368
Mouse
regulation of circadian rhythmGO:0042752580.366
regulation of mast cell differentiationGO:006037530.365
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesisGO:200076410.362
adult behaviorGO:00305341350.360
carbohydrate homeostasisGO:00335001280.355
cell fate commitmentGO:00451652100.355
Mouse
regulation of neuron projection developmentGO:00109751690.355
embryonic placenta developmentGO:0001892980.355
morphogenesis of embryonic epitheliumGO:00163311590.349
Mouse
embryonic skeletal system developmentGO:00487061200.347
Mouse
retina morphogenesis in camera type eyeGO:0060042450.347
regulation of secretionGO:00510462740.337
mechanoreceptor differentiationGO:0042490670.337
epithelial cell proliferationGO:00506731740.335
Mouse
metencephalon developmentGO:0022037890.335
neural retina developmentGO:0003407410.334
Mouse
aortic valve morphogenesisGO:000318040.332
regulation of organ morphogenesisGO:20000271440.331
Mouse
rhythmic processGO:00485111740.329
Mouse
regulation of neural retina developmentGO:006107430.327
Mouse
metanephric loop of henle developmentGO:007223640.323
response to light stimulusGO:00094161350.320
renal system developmentGO:00720012250.319
Mouse
cation transportGO:00068123990.318
mitral valve developmentGO:000317440.318
camera type eye developmentGO:00430102660.314
Mouse
cardiac muscle tissue morphogenesisGO:0055008440.313
regulation of cellular amine metabolic processGO:0033238200.310
hypophysis morphogenesisGO:004885030.305
ossificationGO:00015032160.305
Mouse
negative regulation of cell developmentGO:00107211690.301
Mouse
sclerotome developmentGO:006105640.300
cell fate specificationGO:0001708720.296
Mouse
limb morphogenesisGO:00351081490.295
positive regulation of neuron differentiationGO:00456661410.293
detection of external stimulusGO:0009581610.291
tendon formationGO:003599240.289
mitochondrion distributionGO:004831140.288
regulation of system processGO:00440572000.287
regulation of membrane potentialGO:00423911920.286
negative regulation of synapse maturationGO:200029720.285
cell proliferation involved in outflow tract morphogenesisGO:006132540.279
regulation of auditory receptor cell differentiationGO:004560740.279
negative regulation of peroxisome proliferator activated receptor signaling pathwayGO:003535930.274
cardiac muscle tissue developmentGO:00487381300.274
connective tissue developmentGO:00614481790.272
Mouse
cell proliferation in forebrainGO:0021846300.271
Mouse
cellular amine metabolic processGO:0044106440.271
embryonic epithelial tube formationGO:00018381300.271
Mouse
mesenchymal cell differentiationGO:00487621070.270
Mouse
regulation of body fluid levelsGO:00508781620.267
stem cell proliferationGO:00720891170.266
Mouse
negative regulation of cell cycleGO:00457861230.266
negative regulation of type b pancreatic cell apoptotic processGO:200067530.266
telencephalon cell migrationGO:0022029550.265
rhodopsin mediated signaling pathwayGO:001605640.261
female sex differentiationGO:0046660840.260
blood vessel morphogenesisGO:00485142850.260
Mouse
forebrain generation of neuronsGO:0021872630.257
neuroepithelial cell differentiationGO:0060563370.256
neuron fate determinationGO:004866490.252
developmental maturationGO:00217001930.252
Mouse
myoblast differentiation involved in skeletal muscle regenerationGO:001483530.248
glandular epithelial cell differentiationGO:0002067380.244
detection of abiotic stimulusGO:0009582600.243
pallium developmentGO:00215431200.243
myeloid cell differentiationGO:00300992330.241
ectoderm formationGO:000170530.241
limbic system developmentGO:0021761720.240
regulation of cartilage developmentGO:0061035440.239
Mouse
positive regulation of keratinocyte proliferationGO:001083840.235
deltoid tuberosity developmentGO:003599330.233
gland developmentGO:00487323300.233
Mouse
smoothened signaling pathwayGO:00072241050.233
chondrocyte differentiationGO:0002062720.231
Mouse
mitral valve morphogenesisGO:000318340.228
bmp signaling pathwayGO:0030509930.228
muscle cell differentiationGO:00426922610.227
Mouse
neuroblast proliferationGO:0007405490.226
Mouse
ovulation cycleGO:0042698590.222
carbon catabolite repression of transcription from rna polymerase ii promoterGO:000043710.221
cerebellum developmentGO:0021549770.219
organic hydroxy compound biosynthetic processGO:1901617770.216
positive regulation of nervous system developmentGO:00519622210.216
blood circulationGO:00080151950.215
retinal cone cell developmentGO:004654980.215
cardiac right ventricle formationGO:000321930.214
regulation of axon diameterGO:003113360.213
respiratory gaseous exchangeGO:0007585430.210
hindbrain developmentGO:00309021280.210
skin developmentGO:00435882200.210
ventral spinal cord interneuron fate commitmentGO:0060579140.209
heart formationGO:0060914160.206
Mouse
ureteric bud developmentGO:0001657940.206
Mouse
leukocyte differentiationGO:00025213420.203
b cell differentiationGO:0030183780.201
ameboidal type cell migrationGO:00016671280.201
kidney morphogenesisGO:0060993830.201
Mouse
photoreceptor cell differentiationGO:0046530520.200
Fly
digestive tract developmentGO:00485651900.200
Mouse
cellular amino acid metabolic processGO:00065201030.199
regulation of cell projection organizationGO:00313442060.196
bone developmentGO:00603481200.196
epithelial cell developmentGO:00020641590.195
Mouse
neurohypophysis developmentGO:002198520.192
nephron tubule developmentGO:0072080840.192
Mouse
segmentationGO:0035282930.190
placenta developmentGO:00018901400.190
negative regulation of cell proliferationGO:00082852960.190
Mouse
adult locomotory behaviorGO:0008344910.188
regulation of heart contractionGO:0008016770.188
visceral serous pericardium developmentGO:006103220.188
regulation of stem cell proliferationGO:0072091780.187
Mouse
hormone secretionGO:00468791280.186
cerebral cortex gabaergic interneuron differentiationGO:002189290.184
odontogenesis of dentin containing toothGO:0042475660.184
calcium ion transportGO:00068161590.184
mesenchymal cell developmentGO:0014031930.184
cation transmembrane transportGO:00986552660.183
neuron projection guidanceGO:00974851410.183
positive regulation of secondary heart field cardioblast proliferationGO:007251340.183
Mouse
cell recognitionGO:0008037830.182
atrial cardiac muscle cell differentiationGO:005501120.182
pituitary gland developmentGO:0021983380.182
Mouse
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.181
inorganic cation transmembrane transportGO:00986622070.181
cellular ketone metabolic processGO:0042180840.181
regulation of homeostatic processGO:00328441820.181
organophosphate biosynthetic processGO:00904071220.180
regulation of retina development in camera type eyeGO:190286630.180
Mouse
cell proliferation involved in heart valve developmentGO:200079320.178
positive regulation of semaphorin plexin signaling pathwayGO:200126210.178
regulation of cellular amino acid metabolic processGO:000652150.176
hypothalamus cell differentiationGO:002197980.176
developmental programmed cell deathGO:0010623410.176
positive regulation of exit from mitosisGO:003153610.174
neuron recognitionGO:0008038250.174
spinal cord association neuron differentiationGO:0021527140.173
positive regulation of protein kinase activityGO:00458601440.173
regulation of exit from mitosisGO:000709610.173
erythrocyte differentiationGO:0030218880.172
organonitrogen compound biosynthetic processGO:19015661920.172
nephron developmentGO:00720061090.172
Mouse
positive regulation of stem cell differentiationGO:2000738230.170
positive regulation of cellular amino acid metabolic processGO:004576430.169
semaphorin plexin signaling pathwayGO:0071526210.168
feeding behaviorGO:0007631620.168
t cell activationGO:00421102890.166
eye photoreceptor cell developmentGO:0042462310.165
cerebral cortex neuron differentiationGO:0021895190.164
mesonephric tubule developmentGO:0072164940.163
Mouse
developmental inductionGO:0031128340.163
Mouse
regulation of anatomical structure sizeGO:00900661780.162
lens morphogenesis in camera type eyeGO:0002089240.162
Mouse
cartilage developmentGO:00512161400.161
Mouse
regulation of tube sizeGO:0035150570.161
multi multicellular organism processGO:00447061090.160
regulation of secretion by cellGO:19035302490.160
cardiocyte differentiationGO:0035051870.159
mesenchymal to epithelial transitionGO:0060231120.159
Mouse
bone morphogenesisGO:0060349780.159
cytokine productionGO:00018163190.156
mesenchyme morphogenesisGO:0072132320.155
neural crest cell migrationGO:0001755320.155
positive regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589920.154
regulation of transporter activityGO:0032409570.153
planar cell polarity pathway involved in pericardium morphogenesisGO:006135420.152
positive regulation of synaptic plasticityGO:003191540.152
cerebellum formationGO:002158810.151
regulation of blood pressureGO:0008217930.149
regulation of cellular ketone metabolic processGO:0010565660.149
sensory system developmentGO:004888030.147
midbrain hindbrain boundary maturation during brain developmentGO:002200410.147
multi organism behaviorGO:0051705620.147
cellular homeostasisGO:00197252400.147
regulation of cell migrationGO:00303342190.147
spermatid developmentGO:00072861080.147
Mouse
tendon cell differentiationGO:003599040.146
myeloid leukocyte differentiationGO:00025731190.146
regulation of transmembrane transportGO:00347621280.145
embryonic hindlimb morphogenesisGO:0035116320.145
catecholamine metabolic processGO:0006584300.144
regulation of muscle system processGO:0090257800.144
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112330.144
amine metabolic processGO:0009308450.143
adenohypophysis developmentGO:0021984140.142
proton transportGO:0015992350.142
chemotaxisGO:00069352470.142
b cell activationGO:00421131610.142
regulation of peptide hormone secretionGO:0090276750.141
cardiac muscle cell differentiationGO:0055007690.141
cell differentiation involved in embryonic placenta developmentGO:0060706260.140
respiratory tube developmentGO:00303231670.140
cell cycle arrestGO:0007050370.139
hair cell differentiationGO:0035315400.138
skeletal muscle organ developmentGO:00605381630.138
Mouse
digestionGO:0007586400.138
spinal cord oligodendrocyte cell fate specificationGO:002153030.137
nephron epithelium developmentGO:0072009920.137
Mouse
lateral line system developmentGO:004892510.136
cerebral cortex gabaergic interneuron migrationGO:002185360.135
sensory perception of light stimulusGO:0050953540.134
endochondral bone morphogenesisGO:0060350500.134
potassium ion transmembrane transportGO:0071805430.134
neural tube closureGO:0001843900.134
lung inductionGO:006049230.133
forebrain cell migrationGO:0021885580.131
ureteric bud morphogenesisGO:0060675620.131
Mouse
renal tubule developmentGO:0061326870.131
Mouse
stem cell maintenanceGO:00198271300.131
Mouse
detection of visible lightGO:0009584140.131
wound healingGO:00420601570.131
central nervous system vasculogenesisGO:002200930.130
negative regulation of wnt signaling pathwayGO:0030178730.130
Mouse
brain segmentationGO:003528430.130
amacrine cell differentiationGO:003588150.129
cardiac chamber morphogenesisGO:0003206930.129
cation homeostasisGO:00550802120.127
striated muscle contractionGO:0006941450.127
mesonephric duct formationGO:007218120.127
regulation of osteoblast differentiationGO:0045667670.126
autonomic nervous system developmentGO:0048483430.126
Mouse
action potentialGO:0001508780.126
cell fate determinationGO:0001709320.126
thymus developmentGO:0048538410.124
Mouse
mitochondrial transportGO:0006839360.124
sensory perception of soundGO:0007605970.123
Mouse
trophoblast giant cell differentiationGO:0060707150.123
cellular response to growth factor stimulusGO:00713631970.123
negative regulation of cellular component organizationGO:00511291940.123
regulation of wnt signaling pathwayGO:00301111230.123
Mouse
trophectodermal cell differentiationGO:0001829210.122
hippocampus developmentGO:0021766520.122
cerebral cortex cell migrationGO:0021795440.122
auditory receptor cell differentiationGO:0042491370.121
canonical wnt signaling pathwayGO:00600701300.121
loop of henle developmentGO:0072070100.120
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.119
ventricular cardiac myofibril assemblyGO:005500530.119
cerebral cortex developmentGO:0021987860.119
tongue developmentGO:0043586180.118
Mouse
stem cell differentiationGO:00488632680.118
Mouse
neural precursor cell proliferationGO:00613511210.118
Mouse
spemann organizer formationGO:006006120.118
regulation of cell motilityGO:20001452360.117
regulation of sequence specific dna binding transcription factor activityGO:00510901060.117
insulin secretionGO:0030073890.117
associative learningGO:0008306610.117
muscle contractionGO:00069361010.115
neuromuscular processGO:0050905990.115
maintenance of cell numberGO:009872730.114
cell type specific apoptotic processGO:00972852680.114
Mouse
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus developmentGO:006052840.114
regulation of muscle tissue developmentGO:1901861970.114
Mouse
positive regulation of mapk cascadeGO:00434101700.114
regulation of organ growthGO:0046620610.114
male gamete generationGO:00482322850.113
Mouse
astrocyte differentiationGO:0048708430.113
keratinocyte proliferationGO:0043616210.113
ribonucleotide metabolic processGO:00092592910.112
determination of left right symmetryGO:0007368800.112
regulation of gliogenesisGO:0014013500.112
embryonic skeletal system morphogenesisGO:0048704910.112
Mouse
oviduct developmentGO:006006630.111
striated muscle cell proliferationGO:0014855390.111
Mouse
organ inductionGO:0001759210.110
Mouse
regulation of ion transportGO:00432692150.110
response to radiationGO:00093141650.109
regulation of cell adhesionGO:00301551540.109
regulation of intestinal epithelial structure maintenanceGO:006073010.109
regulation of chondrocyte differentiationGO:0032330330.109
Mouse
cardiac epithelial to mesenchymal transitionGO:0060317180.109
regulation of epithelial cell proliferationGO:00506781410.109
Mouse
nephron tubule morphogenesisGO:0072078680.108
Mouse
artery developmentGO:0060840530.108
Mouse
mesodermal cell differentiationGO:0048333220.108
Mouse
development of primary sexual characteristicsGO:00451371430.107
Mouse
renal inner medulla developmentGO:007205330.107
apoptotic process involved in morphogenesisGO:0060561250.107
primary neural tube formationGO:0014020950.107
synapse organizationGO:00508081250.106
Mouse
endocrine pancreas developmentGO:0031018290.106
dorsal spinal cord developmentGO:0021516200.106
negative regulation of cellular amine metabolic processGO:003323910.106
atrial cardiac muscle cell developmentGO:005501420.105
endocardial cushion to mesenchymal transitionGO:009050050.105
anatomical structure homeostasisGO:00602491450.105
embryonic forelimb morphogenesisGO:0035115320.104
purine ribonucleotide metabolic processGO:00091502900.104
positive regulation of cell motilityGO:20001471160.104
germ cell developmentGO:00072811850.104
Mouse
tissue remodelingGO:00487711020.103
cochlea developmentGO:0090102350.103
Mouse
negative regulation of prostatic bud formationGO:006068640.103
dna templated transcriptional preinitiation complex assemblyGO:007089740.103
epithalamus developmentGO:002153820.103
regulation of astrocyte differentiationGO:0048710200.102
axis elongationGO:0003401300.102
Mouse
regulation of myeloid cell differentiationGO:0045637960.102
lymphocyte differentiationGO:00300982420.102
multi organism reproductive behaviorGO:0044705290.102
organic hydroxy compound metabolic processGO:19016152030.101
atrioventricular valve morphogenesisGO:0003181130.101
protein modification by small protein conjugationGO:00324461870.100
extracellular structure organizationGO:00430621480.099
cellular response to organic cyclic compoundGO:0071407870.099
positive regulation of stem cell proliferationGO:2000648590.099
Mouse
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.099
cardioblast proliferationGO:000326380.098
Mouse
negative regulation of neuron differentiationGO:00456651010.098
Mouse
pancreas developmentGO:0031016570.098
regulation of cytokine productionGO:00018172660.098
ventral spinal cord developmentGO:0021517480.097
angiogenesisGO:00015252010.097
neural tube developmentGO:00219151600.096
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.096
mesenchymal cell proliferationGO:0010463440.096
Mouse
developmental growth involved in morphogenesisGO:00605601380.095
Mouse
stem cell developmentGO:00488642190.095
Mouse
midbrain hindbrain boundary maturationGO:002173210.095
ventral spinal cord interneuron differentiationGO:0021514160.095
neural crest cell developmentGO:0014032480.095
hydrogen transportGO:0006818350.095
nucleoside phosphate metabolic processGO:00067533380.094
tube closureGO:0060606910.093
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferationGO:200008110.093
carbohydrate metabolic processGO:00059752300.093
ventricular cardiac muscle tissue morphogenesisGO:0055010320.093
protein modification by small protein conjugation or removalGO:00706472070.093
regulation of glial cell differentiationGO:0045685410.092
glial cell differentiationGO:00100011310.092
spinal cord oligodendrocyte cell differentiationGO:002152930.092
branching morphogenesis of an epithelial tubeGO:00487541590.092
Mouse
somatotropin secreting cell developmentGO:006013320.091
heart contractionGO:0060047930.091
epidermis developmentGO:00085441870.091
head morphogenesisGO:0060323340.091
positive regulation of voltage gated calcium channel activityGO:190138720.091
apoptotic signaling pathwayGO:00971903060.091
mesoderm morphogenesisGO:0048332640.091
Mouse
extracellular matrix organizationGO:00301981470.090
hormone metabolic processGO:0042445860.090
regulation of kinase activityGO:00435492490.090
regulation of peptide secretionGO:0002791770.090
horizontal cell localizationGO:003585210.090
corticotropin hormone secreting cell differentiationGO:006012830.090
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589820.089
peripheral nervous system neuron developmentGO:004893590.089
thick ascending limb developmentGO:007202320.089
positive regulation of cell migrationGO:00303351090.089
apoptotic process involved in heart morphogenesisGO:000327850.089
specification of organ identityGO:0010092300.088
Mouse
regulation of cell cycleGO:00517262810.087
Mouse
wnt signaling pathway involved in forebrain neuroblast divisionGO:002187420.087
glucose homeostasisGO:00425931280.087
olfactory bulb developmentGO:0021772300.087
dorsal ventral neural tube patterningGO:0021904280.086
fungiform papilla developmentGO:006119660.086
Mouse
cerebellar cortex developmentGO:0021695480.086
kidney epithelium developmentGO:00720731210.086
Mouse
regulation of ossificationGO:00302781120.086
Mouse
activation of adenylate cyclase activityGO:000719040.086
muscle system processGO:00030121410.086
axon guidanceGO:00074111410.085
muscle tissue morphogenesisGO:0060415530.085
heart processGO:0003015940.085
cell adhesionGO:00071553290.085
regulation of mechanoreceptor differentiationGO:004563150.085
cellular chemical homeostasisGO:00550822150.085
spleen developmentGO:0048536390.085
regulation of anagenGO:005188410.085
positive regulation of protein phosphorylationGO:00019342420.085
hexose metabolic processGO:0019318980.084
negative regulation of myeloid cell differentiationGO:0045638380.084
forebrain neuron fate commitmentGO:0021877130.083
regulation of muscle cell apoptotic processGO:0010660170.083
regulation of leukocyte differentiationGO:19021051590.082
midgut developmentGO:000749440.082
retinal ganglion cell axon guidanceGO:0031290180.082
forebrain anterior posterior pattern specificationGO:002179750.082
Mouse
neural tube formationGO:00018411080.081
organelle localizationGO:00516401790.081
cardiac right atrium morphogenesisGO:000321330.081
tube formationGO:00351481400.080
Mouse
ribose phosphate biosynthetic processGO:0046390590.080
intestinal epithelial structure maintenanceGO:006072940.080
regulation of ion transmembrane transportGO:00347651190.080
sensory perception of mechanical stimulusGO:00509541070.080
Mouse
ectodermal cell differentiationGO:001066830.080
peptide secretionGO:00027901140.079
tumor necrosis factor superfamily cytokine productionGO:0071706510.079
regulation of circadian sleep wake cycleGO:004274930.078
purine containing compound biosynthetic processGO:0072522700.078
peripheral nervous system neuron axonogenesisGO:004893630.077
planar cell polarity pathway involved in outflow tract morphogenesisGO:006134720.077
photoreceptor cell developmentGO:0042461400.077
kidney developmentGO:00018222130.077
Mouse
inner cell mass cell fate commitmentGO:000182720.077
bronchiole developmentGO:006043530.077
outflow tract morphogenesisGO:0003151530.077
Mouse
male sex differentiationGO:00466611090.077
Mouse
myotube differentiationGO:00149021050.076
Mouse
regulation of protein transportGO:00512231630.076
response to transforming growth factor betaGO:0071559880.076
regulation of myeloid leukocyte differentiationGO:0002761580.076
determination of heart left right asymmetryGO:0061371480.076
regulation of purine nucleotide metabolic processGO:19005421690.076
protein ubiquitinationGO:00165671710.076
mesoderm formationGO:0001707620.076
Mouse
negative regulation of immune system processGO:00026832090.075
formation of primary germ layerGO:0001704770.075
Mouse
fibroblast growth factor receptor signaling pathwayGO:0008543460.075
cellular response to hormone stimulusGO:00328701500.075

Six6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:005015500.462
disease of anatomical entityDOID:700.462
nervous system diseaseDOID:86300.462
eye and adnexa diseaseDOID:149200.216
eye diseaseDOID:561400.216
retinal diseaseDOID:567900.076