IMP: Integrative Multi-species Prediction

Mus musculus

20 known processes

Slc13a1

solute carrier family 13 (sodium/sulfate symporters), member 1

(Aliases: AI987826,Nas1,AI314066,NaSi-1)

Entrez: 55961
Ensembl: ENSMUSG00000029700
UniProtKB: Q9JHI4

Process Predictions
Disease Predictions

Slc13a1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
inorganic anion transmembrane transport	GO:0098661	29	0.844
ion transmembrane transport	GO:0034220	361	0.720
anion transmembrane transport	GO:0098656	71	0.586
chloride transmembrane transport	GO:1902476	24	0.539
organic anion transport	GO:0015711	137	0.451	Worm Fly
anion transport	GO:0006820	177	0.447
transmembrane transport	GO:0055085	412	0.405
sulfur compound transport	GO:0072348	9	0.397
inorganic anion transport	GO:0015698	43	0.336
organic acid transport	GO:0015849	101	0.320	Worm Fly
sulfate transmembrane transport	GO:1902358	3	0.316
transepithelial chloride transport	GO:0030321	4	0.309
amino acid transmembrane transport	GO:0003333	37	0.289
chloride transport	GO:0006821	32	0.186
nitrogen compound transport	GO:0071705	271	0.155
organic hydroxy compound transport	GO:0015850	93	0.135
digestion	GO:0007586	40	0.128
oligopeptide transmembrane transport	GO:0035672	4	0.128
regulation of membrane potential	GO:0042391	192	0.117
carbohydrate transport	GO:0008643	62	0.115
carboxylic acid transport	GO:0046942	100	0.112	Worm Fly
sperm capacitation	GO:0048240	17	0.112
bicarbonate transport	GO:0015701	7	0.110
monocarboxylic acid transport	GO:0015718	44	0.107	Fly
monocarboxylic acid metabolic process	GO:0032787	191	0.106
cation transport	GO:0006812	399	0.101	Zebrafish Worm
intestinal absorption	GO:0050892	13	0.098
dicarboxylic acid transport	GO:0006835	29	0.095	Worm Fly
inorganic ion transmembrane transport	GO:0098660	234	0.092
cellular alcohol biosynthetic process	GO:0044108	3	0.087
dipeptide transport	GO:0042938	2	0.087
uronic acid metabolic process	GO:0006063	2	0.085
inorganic cation transmembrane transport	GO:0098662	207	0.078	Zebrafish Worm
sulfate transport	GO:0008272	3	0.075
glucuronate metabolic process	GO:0019585	2	0.075
response to organic cyclic compound	GO:0014070	198	0.069
cation transmembrane transport	GO:0098655	266	0.068	Zebrafish Worm
cation homeostasis	GO:0055080	212	0.062
regulation of dipeptide transmembrane transport	GO:2001148	2	0.060
amino acid betaine transport	GO:0015838	3	0.058
oxidative demethylation	GO:0070989	1	0.058
membrane hyperpolarization	GO:0060081	21	0.057
cellular response to fructose stimulus	GO:0071332	2	0.056
regulation of ph	GO:0006885	26	0.056
dipeptide transmembrane transport	GO:0035442	2	0.055
carnitine transport	GO:0015879	3	0.052
cellular response to monosaccharide stimulus	GO:0071326	47	0.051
amino acid transport	GO:0006865	61	0.050
isoprenoid metabolic process	GO:0006720	29	0.049
response to fructose	GO:0009750	2	0.048
response to organonitrogen compound	GO:0010243	246	0.047
cellular amide metabolic process	GO:0043603	58	0.045
cofactor metabolic process	GO:0051186	80	0.044
regulation of microvillus assembly	GO:0032534	3	0.043
action potential	GO:0001508	78	0.043
drug catabolic process	GO:0042737	2	0.043
regulation of oligopeptide transport	GO:0090088	2	0.041
l amino acid transport	GO:0015807	32	0.041
regulation of microvillus organization	GO:0032530	3	0.040
fluid transport	GO:0042044	14	0.038
sensory perception	GO:0007600	245	0.036
cellular lipid metabolic process	GO:0044255	323	0.035
cellular response to organic cyclic compound	GO:0071407	87	0.034
regulation of hormone levels	GO:0010817	211	0.034
spermatid differentiation	GO:0048515	115	0.034
positive regulation of dipeptide transmembrane transport	GO:2001150	2	0.033
monovalent inorganic cation homeostasis	GO:0055067	33	0.033
g protein coupled receptor signaling pathway	GO:0007186	243	0.032
multicellular organism growth	GO:0035264	161	0.031	Worm
carnitine transmembrane transport	GO:1902603	3	0.031
spermatid development	GO:0007286	108	0.030
blood circulation	GO:0008015	195	0.030
ensheathment of neurons	GO:0007272	76	0.029
transmission of nerve impulse	GO:0019226	76	0.029
regulation of dipeptide transport	GO:0090089	2	0.028
steroid metabolic process	GO:0008202	119	0.028
neuronal action potential	GO:0019228	54	0.028
intracellular ph elevation	GO:0051454	3	0.028
sodium ion transmembrane transport	GO:0035725	49	0.026	Zebrafish Worm
oxidation reduction process	GO:0055114	342	0.026
terpenoid metabolic process	GO:0006721	25	0.026
l alpha amino acid transmembrane transport	GO:1902475	23	0.025
glycosyl compound metabolic process	GO:1901657	246	0.025
detection of chemical stimulus involved in sensory perception of taste	GO:0050912	3	0.025
regulation of protein localization	GO:0032880	231	0.025
cellular chemical homeostasis	GO:0055082	215	0.025
organic hydroxy compound metabolic process	GO:1901615	203	0.025
modified amino acid transport	GO:0072337	5	0.025
peptide transport	GO:0015833	133	0.024
negative regulation of immune system process	GO:0002683	209	0.024
amide transport	GO:0042886	138	0.024
neutral amino acid transport	GO:0015804	13	0.024
response to monosaccharide	GO:0034284	67	0.024
ribonucleotide metabolic process	GO:0009259	291	0.024
organonitrogen compound biosynthetic process	GO:1901566	192	0.024
purine nucleotide metabolic process	GO:0006163	302	0.023
response to inorganic substance	GO:0010035	96	0.023
cellular amine metabolic process	GO:0044106	44	0.023
nucleotide metabolic process	GO:0009117	332	0.023
regulation of transforming growth factor beta secretion	GO:2001201	1	0.023
regulation of transmembrane transport	GO:0034762	128	0.023
oxalate transport	GO:0019532	3	0.023
nucleoside phosphate metabolic process	GO:0006753	338	0.023
cellular ion homeostasis	GO:0006873	165	0.022
vitamin d3 metabolic process	GO:0070640	3	0.022
calcitriol biosynthetic process from calciol	GO:0036378	3	0.022
innate immune response	GO:0045087	157	0.022
purine containing compound metabolic process	GO:0072521	311	0.022
naphthalene metabolic process	GO:0018931	1	0.022
fatty acid metabolic process	GO:0006631	121	0.021
response to light stimulus	GO:0009416	135	0.021
methionine transport	GO:0015821	1	0.021
circulatory system process	GO:0003013	197	0.021
organonitrogen compound catabolic process	GO:1901565	264	0.021
cellular response to hexose stimulus	GO:0071331	47	0.021
muscle tissue development	GO:0060537	308	0.021
myelination	GO:0042552	74	0.021
cellular nitrogen compound catabolic process	GO:0044270	280	0.020
heterocycle catabolic process	GO:0046700	280	0.020
protein catabolic process	GO:0030163	221	0.020
negative regulation of endothelial cell migration	GO:0010596	4	0.020
leukocyte chemotaxis	GO:0030595	69	0.020
purine nucleoside metabolic process	GO:0042278	241	0.020
organic cyclic compound catabolic process	GO:1901361	295	0.019
regulation of peptide transport	GO:0090087	91	0.019
cellular alcohol metabolic process	GO:0044107	3	0.019
nucleobase containing small molecule metabolic process	GO:0055086	352	0.019
hexose transmembrane transport	GO:0035428	7	0.019
ribose phosphate metabolic process	GO:0019693	291	0.019
multicellular organismal signaling	GO:0035637	91	0.019
lipid localization	GO:0010876	126	0.019	Worm Fly
organophosphate catabolic process	GO:0046434	232	0.019
inter male aggressive behavior	GO:0002121	3	0.019
macromolecule catabolic process	GO:0009057	281	0.019
amine metabolic process	GO:0009308	45	0.018
negative regulation of blood vessel endothelial cell migration	GO:0043537	3	0.018
sensory organ morphogenesis	GO:0090596	242	0.018
reactive oxygen species metabolic process	GO:0072593	84	0.018
epithelial fluid transport	GO:0042045	1	0.018
progesterone metabolic process	GO:0042448	4	0.018
purine ribonucleotide metabolic process	GO:0009150	290	0.017
negative regulation of nik nf kappab signaling	GO:1901223	2	0.017
regulation of cytokine production	GO:0001817	266	0.017
small molecule biosynthetic process	GO:0044283	132	0.017
developmental maturation	GO:0021700	193	0.017
protein modification by small protein conjugation or removal	GO:0070647	207	0.017
positive regulation of cell development	GO:0010720	237	0.017
polyol transport	GO:0015791	4	0.017
small gtpase mediated signal transduction	GO:0007264	97	0.017
digestive tract development	GO:0048565	190	0.017
ribonucleoside metabolic process	GO:0009119	245	0.017
camera type eye development	GO:0043010	266	0.016
regulation of feeding behavior	GO:0060259	3	0.016
interspecies interaction between organisms	GO:0044419	83	0.016
phenol containing compound metabolic process	GO:0018958	60	0.016
peptide metabolic process	GO:0006518	46	0.016
negative regulation of cytokine production	GO:0001818	84	0.016
cellular homeostasis	GO:0019725	240	0.016
purine containing compound catabolic process	GO:0072523	213	0.016
potassium ion transmembrane transport	GO:0071805	43	0.016
regulation of cell motility	GO:2000145	236	0.016
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.016
sodium ion transport	GO:0006814	73	0.016	Zebrafish Worm
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.015
regulation of innate immune response	GO:0045088	91	0.015
homeostasis of number of cells	GO:0048872	210	0.015
secondary alcohol metabolic process	GO:1902652	3	0.015
acid secretion	GO:0046717	33	0.015
positive regulation of vasoconstriction	GO:0045907	4	0.015
regulation of antimicrobial peptide biosynthetic process	GO:0002805	1	0.015
axon ensheathment	GO:0008366	76	0.015
cellular ketone metabolic process	GO:0042180	84	0.015
aromatic compound catabolic process	GO:0019439	286	0.015
muscle contraction	GO:0006936	101	0.015
response to acid chemical	GO:0001101	111	0.015
carnitine metabolic process	GO:0009437	7	0.015
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.015
cellular amino acid metabolic process	GO:0006520	103	0.015
cellular potassium ion transport	GO:0071804	43	0.015
purine ribonucleoside metabolic process	GO:0046128	241	0.014
drug metabolic process	GO:0017144	4	0.014
regulation of neuron differentiation	GO:0045664	281	0.014
fat soluble vitamin biosynthetic process	GO:0042362	4	0.014
nucleoside catabolic process	GO:0009164	206	0.014
myeloid cell differentiation	GO:0030099	233	0.014
cellular response to oxidative stress	GO:0034599	76	0.014
cellular protein complex assembly	GO:0043623	116	0.014
response to purine containing compound	GO:0014074	28	0.014
regulation of system process	GO:0044057	200	0.014
nucleoside metabolic process	GO:0009116	246	0.014
negative regulation of neuron projection regeneration	GO:0070571	3	0.014
positive regulation of defense response	GO:0031349	124	0.014
glycosyl compound catabolic process	GO:1901658	206	0.013
protein kinase c signaling	GO:0070528	7	0.013
retina development in camera type eye	GO:0060041	119	0.013
exogenous drug catabolic process	GO:0042738	1	0.013
adult behavior	GO:0030534	135	0.013
negative regulation of cell migration	GO:0030336	59	0.013
regulation of blood circulation	GO:1903522	93	0.013
transforming growth factor beta secretion	GO:0038044	1	0.013
cellular response to organonitrogen compound	GO:0071417	145	0.013
oligopeptide transport	GO:0006857	6	0.013
saturated monocarboxylic acid metabolic process	GO:0032788	2	0.013
purine ribonucleotide catabolic process	GO:0009154	208	0.013
negative regulation of cellular amine metabolic process	GO:0033239	1	0.013
ribonucleoside catabolic process	GO:0042454	206	0.013
immune effector process	GO:0002252	321	0.012
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.012
negative regulation of cell development	GO:0010721	169	0.012
steroid biosynthetic process	GO:0006694	47	0.012
actin filament polymerization	GO:0030041	44	0.012
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.012
locomotory behavior	GO:0007626	195	0.012
mannitol transport	GO:0015797	1	0.012
cellular response to peptidoglycan	GO:0071224	4	0.012
male gamete generation	GO:0048232	285	0.012
hydrogen ion transmembrane transport	GO:1902600	25	0.012
purine nucleotide catabolic process	GO:0006195	211	0.012
response to organophosphorus	GO:0046683	22	0.012
cellular response to lipid	GO:0071396	145	0.012
fertilization	GO:0009566	127	0.012
defense response to other organism	GO:0098542	197	0.012
naphthalene containing compound metabolic process	GO:0090420	1	0.012
regulation of hydrolase activity	GO:0051336	246	0.012
regulation of ion transport	GO:0043269	215	0.012
sensory perception of light stimulus	GO:0050953	54	0.012
eye photoreceptor cell development	GO:0042462	31	0.012
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.012
antimicrobial peptide biosynthetic process	GO:0002777	2	0.012
visual perception	GO:0007601	52	0.012
nucleoside monophosphate metabolic process	GO:0009123	85	0.012
cellular response to camp	GO:0071320	11	0.012
potassium ion transport	GO:0006813	52	0.012
protein modification by small protein conjugation	GO:0032446	187	0.012
glucose transport	GO:0015758	56	0.012
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.012
vitamin d biosynthetic process	GO:0042368	3	0.012
cellular response to dna damage stimulus	GO:0006974	207	0.012
posttranscriptional regulation of gene expression	GO:0010608	155	0.011
cellular macromolecule catabolic process	GO:0044265	206	0.011
alpha amino acid metabolic process	GO:1901605	59	0.011
antibacterial peptide biosynthetic process	GO:0002780	2	0.011
purine ribonucleoside monophosphate metabolic process	GO:0009167	80	0.011
purine nucleoside catabolic process	GO:0006152	205	0.011
regulation of cellular ph	GO:0030641	12	0.011
regulation of cellular amine metabolic process	GO:0033238	20	0.011
regulation of cell migration	GO:0030334	219	0.011
lateral inhibition	GO:0046331	1	0.011
heart contraction	GO:0060047	93	0.011
protein maturation	GO:0051604	176	0.011
regulation of norepinephrine secretion	GO:0014061	2	0.011
myeloid cell homeostasis	GO:0002262	114	0.011
regulation of anatomical structure size	GO:0090066	178	0.011
norepinephrine transport	GO:0015874	2	0.011
response to nutrient levels	GO:0031667	109	0.011
purine nucleoside monophosphate metabolic process	GO:0009126	81	0.011
membrane organization	GO:0061024	245	0.011
small molecule catabolic process	GO:0044282	71	0.011
regulation of circadian sleep wake cycle sleep	GO:0045187	3	0.011
nucleoside triphosphate metabolic process	GO:0009141	230	0.011
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.011
organic acid catabolic process	GO:0016054	51	0.011
negative regulation of cell motility	GO:2000146	61	0.011
lymphocyte mediated immunity	GO:0002449	139	0.011
coenzyme metabolic process	GO:0006732	52	0.011
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.011
memory	GO:0007613	58	0.010
norepinephrine secretion	GO:0048243	2	0.010
rhodopsin mediated signaling pathway	GO:0016056	4	0.010
regulation of cell projection organization	GO:0031344	206	0.010
photoreceptor cell development	GO:0042461	40	0.010
regulation of cellular catabolic process	GO:0031329	242	0.010
response to lipopolysaccharide	GO:0032496	128	0.010
respiratory gaseous exchange	GO:0007585	43	0.010
nucleoside triphosphate catabolic process	GO:0009143	205	0.010
maintenance of location	GO:0051235	89	0.010	Worm Fly
regulation of transferase activity	GO:0051338	263	0.010
ribonucleotide catabolic process	GO:0009261	208	0.010
serotonin uptake	GO:0051610	3	0.010
negative regulation of viral transcription	GO:0032897	3	0.010
regulation of actin nucleation	GO:0051125	4	0.010
positive regulation of oligopeptide transport	GO:2000878	2	0.010
actin polymerization or depolymerization	GO:0008154	54	0.010
muscle system process	GO:0003012	141	0.010
positive regulation of cell migration	GO:0030335	109	0.010

Slc13a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.030
disease of anatomical entity	DOID:7	0.015
nervous system disease	DOID:863	0.015
inherited metabolic disorder	DOID:655	0.013
immune system disease	DOID:2914	0.011

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