IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Slc22a13

solute carrier family 22 (organic cation transporter), member 13

(Aliases: AI648912,OCTL3,OCTL1,ORCTL3)

Entrez: 102570
Ensembl: ENSMUSG00000074028
UniProtKB: Q6A4L0

Process Predictions
Disease Predictions

Slc22a13 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
amino acid transmembrane transport	GO:0003333	37	0.794	Mouse
anion transmembrane transport	GO:0098656	71	0.619	Mouse
ion transmembrane transport	GO:0034220	361	0.480	Mouse
nitrogen compound transport	GO:0071705	271	0.401	Human Mouse
inorganic anion transmembrane transport	GO:0098661	29	0.394
carnitine transmembrane transport	GO:1902603	3	0.361	Mouse
amino acid betaine metabolic process	GO:0006577	7	0.360	Mouse
carboxylic acid transport	GO:0046942	100	0.348	Human Mouse
transmembrane transport	GO:0055085	412	0.319	Mouse
anion transport	GO:0006820	177	0.289	Human Mouse
amino acid transport	GO:0006865	61	0.258	Mouse
chloride transmembrane transport	GO:1902476	24	0.201
organic anion transport	GO:0015711	137	0.177	Human Mouse
amino acid betaine transport	GO:0015838	3	0.148	Mouse
inorganic anion transport	GO:0015698	43	0.145
urate transport	GO:0015747	1	0.115	Human
regulation of neurotransmitter levels	GO:0001505	87	0.103
carnitine metabolic process	GO:0009437	7	0.101	Mouse
toxin transport	GO:1901998	38	0.097	Mouse
cation transmembrane transport	GO:0098655	266	0.091	Mouse
organic hydroxy compound transport	GO:0015850	93	0.087	Mouse
leukocyte migration	GO:0050900	124	0.084
synaptic transmission	GO:0007268	329	0.075
positive regulation of cell death	GO:0010942	224	0.073
regulation of cell motility	GO:2000145	236	0.073
regulation of ion transport	GO:0043269	215	0.073
inorganic ion transmembrane transport	GO:0098660	234	0.070
monoamine transport	GO:0015844	33	0.069
cofactor metabolic process	GO:0051186	80	0.066
neurotransmitter transport	GO:0006836	76	0.065
camera type eye development	GO:0043010	266	0.061
hexose transmembrane transport	GO:0035428	7	0.059
positive regulation of dopamine secretion	GO:0033603	2	0.059
regulation of secretion	GO:0051046	274	0.054
cellular amino acid metabolic process	GO:0006520	103	0.054
histamine uptake	GO:0051615	1	0.050
regulation of cell projection organization	GO:0031344	206	0.050
regulation of cytokine production	GO:0001817	266	0.049
skin development	GO:0043588	220	0.049
cellular response to growth factor stimulus	GO:0071363	197	0.047
regulation of secretion by cell	GO:1903530	249	0.046
positive regulation of apoptotic process	GO:0043065	217	0.046
hydrogen ion transmembrane transport	GO:1902600	25	0.046
kidney development	GO:0001822	213	0.045
positive regulation of defense response	GO:0031349	124	0.043
t cell activation	GO:0042110	289	0.042
multicellular organismal signaling	GO:0035637	91	0.042
organic hydroxy compound metabolic process	GO:1901615	203	0.042	Mouse
sulfur compound transport	GO:0072348	9	0.042
response to lipopolysaccharide	GO:0032496	128	0.041
positive regulation of leukocyte differentiation	GO:1902107	86	0.041
chloride transport	GO:0006821	32	0.041
regulation of membrane potential	GO:0042391	192	0.040
subpallium neuron fate commitment	GO:0060163	2	0.040
cation transport	GO:0006812	399	0.038	Mouse
cognition	GO:0050890	149	0.038
organonitrogen compound biosynthetic process	GO:1901566	192	0.038
action potential	GO:0001508	78	0.038
carnitine transport	GO:0015879	3	0.037	Mouse
neutrophil migration	GO:1990266	37	0.037
sensory perception of light stimulus	GO:0050953	54	0.036
digestion	GO:0007586	40	0.036
regulation of cellular amine metabolic process	GO:0033238	20	0.036
neuronal action potential	GO:0019228	54	0.035
negative regulation of immune system process	GO:0002683	209	0.035
regulation of multi organism process	GO:0043900	111	0.034
amine metabolic process	GO:0009308	45	0.034
response to acid chemical	GO:0001101	111	0.034
regulation of cell activation	GO:0050865	289	0.033
positive regulation of catecholamine secretion	GO:0033605	2	0.033
regulation of lymphocyte differentiation	GO:0045619	107	0.032
positive regulation of cell activation	GO:0050867	158	0.031
modified amino acid transport	GO:0072337	5	0.031	Mouse
cytokine production	GO:0001816	319	0.031
renal system development	GO:0072001	225	0.031
transmission of nerve impulse	GO:0019226	76	0.030
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.030
embryonic placenta development	GO:0001892	98	0.030
regulation of t cell differentiation	GO:0045580	83	0.029
locomotory behavior	GO:0007626	195	0.029
learning	GO:0007612	98	0.029
organic acid transport	GO:0015849	101	0.029	Human Mouse
cell chemotaxis	GO:0060326	81	0.029
regulation of cell cycle	GO:0051726	281	0.028
potassium ion homeostasis	GO:0055075	4	0.028
l amino acid transport	GO:0015807	32	0.028
stem cell differentiation	GO:0048863	268	0.027
response to molecule of bacterial origin	GO:0002237	143	0.027
positive regulation of t cell differentiation	GO:0045582	52	0.027
spermatid differentiation	GO:0048515	115	0.026
positive regulation of cell motility	GO:2000147	116	0.026
reactive oxygen species metabolic process	GO:0072593	84	0.026
cellular amine metabolic process	GO:0044106	44	0.025
regulation of saliva secretion	GO:0046877	2	0.025
regulation of cell migration	GO:0030334	219	0.025
forebrain development	GO:0030900	302	0.025
single organism cell adhesion	GO:0098602	156	0.025
body fluid secretion	GO:0007589	53	0.025
leukocyte chemotaxis	GO:0030595	69	0.025
positive regulation of secretion	GO:0051047	130	0.025
monocarboxylic acid metabolic process	GO:0032787	191	0.024	Mouse
positive regulation of programmed cell death	GO:0043068	218	0.024
regulation of system process	GO:0044057	200	0.024
learning or memory	GO:0007611	148	0.024
positive regulation of ion transport	GO:0043270	65	0.024
metal ion homeostasis	GO:0055065	189	0.024
response to organonitrogen compound	GO:0010243	246	0.023
response to inorganic substance	GO:0010035	96	0.023
regulation of t cell proliferation	GO:0042129	92	0.023
gland development	GO:0048732	330	0.023
response to growth factor	GO:0070848	198	0.023
positive regulation of innate immune response	GO:0045089	80	0.023
myeloid cell differentiation	GO:0030099	233	0.023
negative regulation of t cell activation	GO:0050868	65	0.023
placenta development	GO:0001890	140	0.023
divalent inorganic cation homeostasis	GO:0072507	138	0.023
muscle tissue development	GO:0060537	308	0.023
skeletal muscle organ development	GO:0060538	163	0.022
cellular chemical homeostasis	GO:0055082	215	0.022
cellular response to lipid	GO:0071396	145	0.022
maintenance of location	GO:0051235	89	0.022
peptidyl amino acid modification	GO:0018193	336	0.022
chemotaxis	GO:0006935	247	0.022
myeloid leukocyte migration	GO:0097529	57	0.021
exocytosis	GO:0006887	121	0.021
immune effector process	GO:0002252	321	0.021
inorganic cation transmembrane transport	GO:0098662	207	0.021
response to amino acid	GO:0043200	37	0.021
nuclear transport	GO:0051169	139	0.021
insulin secretion	GO:0030073	89	0.021
positive regulation of leukocyte proliferation	GO:0070665	73	0.021
neutral amino acid transport	GO:0015804	13	0.021
glial cell differentiation	GO:0010001	131	0.021
positive regulation of lymphocyte differentiation	GO:0045621	61	0.021
nerve development	GO:0021675	67	0.021
negative regulation of cellular component organization	GO:0051129	194	0.021
sensory perception	GO:0007600	245	0.020
response to radiation	GO:0009314	165	0.020
leukocyte proliferation	GO:0070661	172	0.020
morphogenesis of embryonic epithelium	GO:0016331	159	0.020
lymphocyte proliferation	GO:0046651	164	0.020
visual perception	GO:0007601	52	0.019
cellular modified amino acid metabolic process	GO:0006575	63	0.019
glycine transport	GO:0015816	4	0.019
neuron neuron synaptic transmission	GO:0007270	69	0.019
fluid transport	GO:0042044	14	0.019
granulocyte migration	GO:0097530	43	0.019
sodium ion transport	GO:0006814	73	0.018
urogenital system development	GO:0001655	261	0.018
leukocyte differentiation	GO:0002521	342	0.018
divalent inorganic cation transport	GO:0072511	178	0.018
blood vessel morphogenesis	GO:0048514	285	0.018
regulation of t cell activation	GO:0050863	170	0.018
sodium ion transmembrane transport	GO:0035725	49	0.018
neuron apoptotic process	GO:0051402	142	0.018
nucleocytoplasmic transport	GO:0006913	139	0.018
regulation of neuron projection development	GO:0010975	169	0.018
cytokine metabolic process	GO:0042107	71	0.018
metanephric loop of henle development	GO:0072236	4	0.018
regulation of lymphocyte activation	GO:0051249	240	0.017
regulation of neuron apoptotic process	GO:0043523	122	0.017
cation homeostasis	GO:0055080	212	0.017
histamine transport	GO:0051608	2	0.017
regulation of amine transport	GO:0051952	21	0.017
spermatogenesis	GO:0007283	284	0.017
peptidyl tyrosine phosphorylation	GO:0018108	143	0.017
energy coupled proton transmembrane transport against electrochemical gradient	GO:0015988	3	0.017
digestive tract development	GO:0048565	190	0.017
response to water deprivation	GO:0009414	1	0.017
granulocyte chemotaxis	GO:0071621	39	0.016
regulation of organelle organization	GO:0033043	289	0.016
regulation of neuron death	GO:1901214	134	0.016
regulation of body fluid levels	GO:0050878	162	0.016
cellular lipid metabolic process	GO:0044255	323	0.016	Mouse
adult behavior	GO:0030534	135	0.016
negative regulation of lymphocyte activation	GO:0051250	91	0.016
spermatid development	GO:0007286	108	0.016
multicellular organismal homeostasis	GO:0048871	164	0.016
intrinsic apoptotic signaling pathway	GO:0097193	132	0.016
positive regulation of lymphocyte activation	GO:0051251	140	0.016
regulation of cellular component biogenesis	GO:0044087	181	0.016
epithelial cell development	GO:0002064	159	0.016
monocarboxylic acid transport	GO:0015718	44	0.016	Human Mouse
positive regulation of defense response to bacterium	GO:1900426	1	0.016
spinal cord oligodendrocyte cell fate specification	GO:0021530	3	0.016
tube formation	GO:0035148	140	0.015
peptide metabolic process	GO:0006518	46	0.015
positive regulation of cell development	GO:0010720	237	0.015
regulation of thymocyte migration	GO:2000410	2	0.015
succinate transport	GO:0015744	1	0.015
cellular ion homeostasis	GO:0006873	165	0.015
regulation of peptide transport	GO:0090087	91	0.015
multicellular organism growth	GO:0035264	161	0.015
b cell activation	GO:0042113	161	0.015
regulation of production of molecular mediator of immune response	GO:0002700	65	0.015
symbiosis encompassing mutualism through parasitism	GO:0044403	83	0.015
inter male aggressive behavior	GO:0002121	3	0.015
alpha amino acid metabolic process	GO:1901605	59	0.015
neutrophil chemotaxis	GO:0030593	36	0.014
t cell differentiation	GO:0030217	174	0.014
positive regulation of amine transport	GO:0051954	8	0.014
regulation of ph	GO:0006885	26	0.014
cell type specific apoptotic process	GO:0097285	268	0.014
negative regulation of secretion by cell	GO:1903531	54	0.014
cellular amide metabolic process	GO:0043603	58	0.014
negative regulation of immune effector process	GO:0002698	55	0.014
neuroblast differentiation	GO:0014016	2	0.014
telencephalon development	GO:0021537	186	0.014
chromatin modification	GO:0016568	187	0.014
serotonin uptake	GO:0051610	3	0.014
regulation of anion transport	GO:0044070	27	0.014
regulation of lymphocyte proliferation	GO:0050670	117	0.014
central nervous system neuron differentiation	GO:0021953	162	0.013
developmental maturation	GO:0021700	193	0.013
response to organic cyclic compound	GO:0014070	198	0.013	Mouse
neurotransmitter uptake	GO:0001504	14	0.013
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.013
actin filament organization	GO:0007015	113	0.013
dicarboxylic acid transport	GO:0006835	29	0.013
positive regulation of t cell activation	GO:0050870	101	0.013
cellular response to prostaglandin stimulus	GO:0071379	2	0.013
medulla oblongata development	GO:0021550	3	0.013
cellular metal ion homeostasis	GO:0006875	151	0.013
regulation of mitotic cell cycle	GO:0007346	126	0.013
germ cell development	GO:0007281	185	0.013
epidermis development	GO:0008544	187	0.013
defense response to virus	GO:0051607	68	0.013
spinal cord oligodendrocyte cell differentiation	GO:0021529	3	0.013
ensheathment of neurons	GO:0007272	76	0.013
compound eye development	GO:0048749	1	0.012
memory	GO:0007613	58	0.012
neural tube development	GO:0021915	160	0.012
regulation of vesicle mediated transport	GO:0060627	139	0.012
protein catabolic process	GO:0030163	221	0.012
amine transport	GO:0015837	21	0.012
retina development in camera type eye	GO:0060041	119	0.012
regulation of metal ion transport	GO:0010959	106	0.012
regulation of acetylcholine secretion neurotransmission	GO:0014056	2	0.012
sperm motility	GO:0030317	47	0.012
glycosyl compound metabolic process	GO:1901657	246	0.012
t cell proliferation	GO:0042098	120	0.012
amide transport	GO:0042886	138	0.012
protein ubiquitination	GO:0016567	171	0.012
positive regulation of cytokine production	GO:0001819	174	0.012
homeostasis of number of cells	GO:0048872	210	0.012
peptidyl tyrosine modification	GO:0018212	145	0.012
cellular response to cytokine stimulus	GO:0071345	189	0.012
cellular homeostasis	GO:0019725	240	0.012
negative regulation of secretion	GO:0051048	61	0.012
neuron death	GO:0070997	154	0.012
cell cell adhesion	GO:0098609	41	0.012
regulation of neuron differentiation	GO:0045664	281	0.012
regulation of sequence specific dna binding transcription factor activity	GO:0051090	106	0.012
oligopeptide transmembrane transport	GO:0035672	4	0.012
positive regulation of cell projection organization	GO:0031346	95	0.012
cellular response to peptidoglycan	GO:0071224	4	0.012
lipid localization	GO:0010876	126	0.012
negative regulation of serotonin secretion	GO:0014063	2	0.012
ameboidal type cell migration	GO:0001667	128	0.012
negative regulation of mitotic cell cycle	GO:0045930	58	0.012
carbohydrate derivative biosynthetic process	GO:1901137	183	0.012
carbon catabolite activation of transcription	GO:0045991	4	0.011
cellular response to organonitrogen compound	GO:0071417	145	0.011
inner ear receptor cell differentiation	GO:0060113	61	0.011
cellular divalent inorganic cation homeostasis	GO:0072503	127	0.011
macromolecule catabolic process	GO:0009057	281	0.011
proton transport	GO:0015992	35	0.011
endocytosis	GO:0006897	168	0.011
stem cell fate determination	GO:0048867	2	0.011
positive regulation of cell migration	GO:0030335	109	0.011
single organismal cell cell adhesion	GO:0016337	131	0.011
negative regulation of cytokine production	GO:0001818	84	0.011
associative learning	GO:0008306	61	0.011
interleukin 18 production	GO:0032621	4	0.011
ossification	GO:0001503	216	0.011
pons development	GO:0021548	13	0.011
actin polymerization or depolymerization	GO:0008154	54	0.011
dopamine catabolic process	GO:0042420	4	0.011
dendrite development	GO:0016358	115	0.011
nuclear import	GO:0051170	95	0.011
response to water	GO:0009415	1	0.011
positive regulation of homeostatic process	GO:0032846	64	0.011
protein localization to organelle	GO:0033365	185	0.011
regulation of symbiosis encompassing mutualism through parasitism	GO:0043903	52	0.011
negative regulation of protein transport	GO:0051224	46	0.011
response to fructose	GO:0009750	2	0.011
peptide transport	GO:0015833	133	0.011
cell activation involved in immune response	GO:0002263	126	0.011
metanephros development	GO:0001656	79	0.011
dopamine metabolic process	GO:0042417	23	0.011
visual learning	GO:0008542	44	0.011
regulation of dopamine secretion	GO:0014059	9	0.011
male gamete generation	GO:0048232	285	0.011
protein import into nucleus	GO:0006606	95	0.011
regulation of cellular response to growth factor stimulus	GO:0090287	82	0.011
regulation of transmembrane transport	GO:0034762	128	0.011
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	194	0.011
membrane organization	GO:0061024	245	0.011
negative regulation of sterol transport	GO:0032372	4	0.011
striated muscle cell development	GO:0055002	125	0.010
adult locomotory behavior	GO:0008344	91	0.010
engulfment of apoptotic cell	GO:0043652	3	0.010
sulfur compound metabolic process	GO:0006790	100	0.010
peptidyl lysine modification	GO:0018205	77	0.010
regulation of leukocyte differentiation	GO:1902105	159	0.010
axon ensheathment	GO:0008366	76	0.010
regulation of peptide secretion	GO:0002791	77	0.010
catecholamine transport	GO:0051937	21	0.010
oxidation reduction process	GO:0055114	342	0.010
neural precursor cell proliferation	GO:0061351	121	0.010
cellular response to abiotic stimulus	GO:0071214	56	0.010
alpha beta t cell activation	GO:0046631	91	0.010
ribonucleoside metabolic process	GO:0009119	245	0.010
sulfate transmembrane transport	GO:1902358	3	0.010
developmental growth involved in morphogenesis	GO:0060560	138	0.010

Slc22a13 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.024
urinary system disease	DOID:18	0.024
cancer	DOID:162	0.014
disease of cellular proliferation	DOID:14566	0.014
organ system cancer	DOID:0050686	0.014
kidney disease	DOID:557	0.013

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