IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Slc39a7

solute carrier family 39 (zinc transporter), member 7

(Aliases: Ring5,H2-Ke4,H-2Ke4,AA408174,Ke-4,AL024048,AI117660,Ke4,Zip7,MGC143815,MGC143814)

Ensembl: ENSMUSG00000024327
Entrez: 14977
UniProtKB: Q31125
UniProtKB: A0A068BIT0

Process Predictions
Disease Predictions

Slc39a7 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
glycoprotein biosynthetic process	GO:0009101	89	0.491
macromolecule glycosylation	GO:0043413	55	0.375
membrane organization	GO:0061024	245	0.257
ion transmembrane transport	GO:0034220	361	0.249	Mouse
glycosylation	GO:0070085	62	0.232
protein n linked glycosylation	GO:0006487	12	0.229
carbohydrate metabolic process	GO:0005975	230	0.218
er to golgi vesicle mediated transport	GO:0006888	11	0.186
response to unfolded protein	GO:0006986	21	0.182
response to endoplasmic reticulum stress	GO:0034976	53	0.160
vesicle organization	GO:0016050	60	0.157
endoplasmic reticulum unfolded protein response	GO:0030968	19	0.154
purine nucleoside catabolic process	GO:0006152	205	0.151
regulation of interleukin 5 secretion	GO:2000662	2	0.148
peptidyl proline hydroxylation	GO:0019511	3	0.133
purine containing compound catabolic process	GO:0072523	213	0.121
negative regulation of fatty acid oxidation	GO:0046322	5	0.120
transmembrane transport	GO:0055085	412	0.105	Mouse
organic anion transport	GO:0015711	137	0.102
carbohydrate derivative biosynthetic process	GO:1901137	183	0.086
purine ribonucleoside catabolic process	GO:0046130	205	0.085
entry into cell of other organism involved in symbiotic interaction	GO:0051806	15	0.085
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.084
regulation of interleukin 10 secretion	GO:2001179	4	0.081
positive regulation of t helper 2 cell activation	GO:2000570	2	0.079
positive regulation of programmed cell death	GO:0043068	218	0.077
anion transmembrane transport	GO:0098656	71	0.076
organophosphate catabolic process	GO:0046434	232	0.075
nucleotide metabolic process	GO:0009117	332	0.074
nucleoside phosphate catabolic process	GO:1901292	222	0.073
interleukin 5 secretion	GO:0072603	2	0.072
copii coated vesicle budding	GO:0090114	2	0.072
golgi vesicle transport	GO:0048193	30	0.071
purine ribonucleotide catabolic process	GO:0009154	208	0.070
multicellular organism growth	GO:0035264	161	0.066
glycoprotein metabolic process	GO:0009100	116	0.065
purine nucleotide metabolic process	GO:0006163	302	0.065
positive regulation of interleukin 5 secretion	GO:2000664	1	0.064
endomembrane system organization	GO:0010256	147	0.063
nucleoside triphosphate catabolic process	GO:0009143	205	0.062
protein hydroxylation	GO:0018126	4	0.061
cellular amino acid metabolic process	GO:0006520	103	0.060
anion transport	GO:0006820	177	0.060
aromatic compound catabolic process	GO:0019439	286	0.057
er nucleus signaling pathway	GO:0006984	27	0.056
regulation of interleukin 13 secretion	GO:2000665	2	0.053
ribonucleotide catabolic process	GO:0009261	208	0.053
response to pain	GO:0048265	26	0.051
ossification	GO:0001503	216	0.051
cellular macromolecule catabolic process	GO:0044265	206	0.050
nucleoside phosphate metabolic process	GO:0006753	338	0.050
glycosyl compound metabolic process	GO:1901657	246	0.049
positive regulation of interleukin 13 secretion	GO:2000667	1	0.049
nucleobase containing small molecule metabolic process	GO:0055086	352	0.049
negative regulation of synapse assembly	GO:0051964	3	0.047
cation transmembrane transport	GO:0098655	266	0.046	Mouse
regulation of fatty acid beta oxidation	GO:0031998	1	0.045
cytoplasmic transport	GO:0016482	234	0.045
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.044
t helper 2 cell activation	GO:0035712	2	0.044
positive regulation of interleukin 10 secretion	GO:2001181	1	0.044
regulation of protein complex assembly	GO:0043254	83	0.044
protein targeting to membrane	GO:0006612	20	0.043
negative regulation of fatty acid transport	GO:2000192	1	0.042
regulation of ral protein signal transduction	GO:0032485	4	0.042
regulation of nucleotide metabolic process	GO:0006140	169	0.042
positive regulation of cell death	GO:0010942	224	0.042
fatty acid transmembrane transport	GO:1902001	1	0.042
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.041
cation transport	GO:0006812	399	0.041	Mouse
inorganic ion transmembrane transport	GO:0098660	234	0.040	Mouse
protein glycosylation	GO:0006486	55	0.040
nucleotide catabolic process	GO:0009166	217	0.038
nucleoside metabolic process	GO:0009116	246	0.037
localization within membrane	GO:0051668	4	0.037
cellular response to topologically incorrect protein	GO:0035967	25	0.037
carbohydrate derivative catabolic process	GO:1901136	231	0.037
positive regulation of t helper 2 cell cytokine production	GO:2000553	3	0.036
ribonucleotide metabolic process	GO:0009259	291	0.036
purine nucleoside metabolic process	GO:0042278	241	0.036
renal system development	GO:0072001	225	0.036
sphingolipid metabolic process	GO:0006665	45	0.035
protein transmembrane transport	GO:0071806	8	0.033
interleukin 13 secretion	GO:0072611	2	0.033
sensory organ morphogenesis	GO:0090596	242	0.033
neuronal action potential	GO:0019228	54	0.032
viral process	GO:0016032	41	0.032
organic acid transport	GO:0015849	101	0.032
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.032
peptidyl proline hydroxylation to 4 hydroxy l proline	GO:0018401	2	0.031
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.031
response to topologically incorrect protein	GO:0035966	25	0.031
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.030
organic cyclic compound catabolic process	GO:1901361	295	0.030
gland development	GO:0048732	330	0.030
positive regulation of dna templated transcription elongation	GO:0032786	2	0.030
positive regulation of transcription elongation from rna polymerase ii promoter	GO:0032968	2	0.030
organonitrogen compound catabolic process	GO:1901565	264	0.029
nucleoside triphosphate metabolic process	GO:0009141	230	0.029
forebrain development	GO:0030900	302	0.028
negative regulation of cellular catabolic process	GO:0031330	47	0.028
entry into host	GO:0044409	15	0.028
heterocycle catabolic process	GO:0046700	280	0.028
ribonucleoside metabolic process	GO:0009119	245	0.028
posttranslational protein targeting to membrane	GO:0006620	2	0.027
t helper 2 cell cytokine production	GO:0035745	4	0.027
carboxylic acid transport	GO:0046942	100	0.027
establishment of protein localization to membrane	GO:0090150	54	0.027
cellular nitrogen compound catabolic process	GO:0044270	280	0.027
positive regulation of apoptotic signaling pathway	GO:2001235	95	0.026
glycogen cell differentiation involved in embryonic placenta development	GO:0060709	1	0.026
leukocyte mediated immunity	GO:0002443	174	0.026
transmission of nerve impulse	GO:0019226	76	0.025
regulation of cellular component biogenesis	GO:0044087	181	0.025
multi organism behavior	GO:0051705	62	0.025
negative regulation of molecular function	GO:0044092	258	0.025
purine ribonucleoside metabolic process	GO:0046128	241	0.025
fertilization	GO:0009566	127	0.025
purine containing compound metabolic process	GO:0072521	311	0.025
mucopolysaccharide metabolic process	GO:1903510	25	0.024
rna processing	GO:0006396	105	0.024	Mouse
male gamete generation	GO:0048232	285	0.024
purine nucleotide catabolic process	GO:0006195	211	0.024
retina development in camera type eye	GO:0060041	119	0.023
cd4 positive alpha beta t cell cytokine production	GO:0035743	4	0.023
circadian regulation of gene expression	GO:0032922	48	0.023
glycosyl compound catabolic process	GO:1901658	206	0.023
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002460	145	0.023
peptidyl asparagine modification	GO:0018196	1	0.022
action potential	GO:0001508	78	0.022
cation homeostasis	GO:0055080	212	0.022
nucleoside catabolic process	GO:0009164	206	0.022
inter male aggressive behavior	GO:0002121	3	0.022
multicellular organismal signaling	GO:0035637	91	0.021
monocarboxylic acid metabolic process	GO:0032787	191	0.021
camera type eye development	GO:0043010	266	0.021
organelle fusion	GO:0048284	28	0.021
positive regulation of protein modification process	GO:0031401	299	0.021
regulation of epithelial cell proliferation	GO:0050678	141	0.021
reproductive behavior	GO:0019098	32	0.020
negative regulation of cell projection organization	GO:0031345	56	0.020
peptidyl proline modification	GO:0018208	6	0.020
regulation of secretion	GO:0051046	274	0.020
negative regulation of cellular component organization	GO:0051129	194	0.020
mitotic cell cycle	GO:0000278	195	0.020
wnt signaling pathway	GO:0016055	188	0.020
guanosine containing compound metabolic process	GO:1901068	144	0.020
diencephalon development	GO:0021536	63	0.020
multi multicellular organism process	GO:0044706	109	0.020
positive regulation of reactive oxygen species biosynthetic process	GO:1903428	2	0.019
long term synaptic depression	GO:0060292	13	0.019
cellular chemical homeostasis	GO:0055082	215	0.019
ribonucleoside catabolic process	GO:0042454	206	0.019
dendrite regeneration	GO:0031104	1	0.019
positive regulation of extrinsic apoptotic signaling pathway	GO:2001238	34	0.019
protein localization to organelle	GO:0033365	185	0.018
ensheathment of neurons	GO:0007272	76	0.018
purine ribonucleotide metabolic process	GO:0009150	290	0.018
positive regulation of secretion	GO:0051047	130	0.018
hematopoietic progenitor cell differentiation	GO:0002244	143	0.018
cell type specific apoptotic process	GO:0097285	268	0.018
heart morphogenesis	GO:0003007	178	0.018
ribose phosphate metabolic process	GO:0019693	291	0.018
cochlear nucleus development	GO:0021747	4	0.017
rhythmic process	GO:0048511	174	0.017
negative regulation of cellular amine metabolic process	GO:0033239	1	0.017
membrane fusion	GO:0061025	38	0.017
kidney development	GO:0001822	213	0.017
guanosine containing compound catabolic process	GO:1901069	144	0.017
regionalization	GO:0003002	337	0.017
regulation of cell motility	GO:2000145	236	0.017	Fly
axon ensheathment	GO:0008366	76	0.017
regulation of cellular ketone metabolic process	GO:0010565	66	0.017
regulation of nuclear transcribed mrna poly a tail shortening	GO:0060211	4	0.017
response to starvation	GO:0042594	65	0.016	Mouse
male anatomical structure morphogenesis	GO:0090598	4	0.016
positive regulation of cellular component biogenesis	GO:0044089	94	0.016
macromolecule catabolic process	GO:0009057	281	0.016
regulation of cellular catabolic process	GO:0031329	242	0.016
spermatogenesis	GO:0007283	284	0.016
regulation of protein secretion	GO:0050708	82	0.016
positive regulation of growth	GO:0045927	104	0.015
cargo loading into vesicle	GO:0035459	3	0.015
positive regulation of apoptotic cell clearance	GO:2000427	3	0.015
positive regulation of vesicle fusion	GO:0031340	2	0.015
regulation of purine nucleotide catabolic process	GO:0033121	122	0.015
regulation of establishment of protein localization	GO:0070201	181	0.015
spongiotrophoblast layer development	GO:0060712	15	0.015
positive regulation of cellular amine metabolic process	GO:0033240	5	0.015
response to uv a	GO:0070141	1	0.015
positive regulation of protein targeting to membrane	GO:0090314	7	0.015
negative regulation of protein complex disassembly	GO:0043242	22	0.015
skin development	GO:0043588	220	0.015
regulation of membrane potential	GO:0042391	192	0.015
endocytosis	GO:0006897	168	0.015
lymphocyte mediated immunity	GO:0002449	139	0.014
fat cell differentiation	GO:0045444	160	0.014
response to sterol	GO:0036314	4	0.014
reactive nitrogen species metabolic process	GO:2001057	0	0.014
ribonucleoside monophosphate catabolic process	GO:0009158	57	0.014
photoreceptor cell differentiation	GO:0046530	52	0.014
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO:0002822	87	0.014
regulation of vesicle fusion	GO:0031338	6	0.014
negative regulation of actin filament polymerization	GO:0030837	11	0.014
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.014
inorganic cation transmembrane transport	GO:0098662	207	0.014	Mouse
canonical wnt signaling pathway	GO:0060070	130	0.014
positive regulation of reactive oxygen species metabolic process	GO:2000379	11	0.014
negative regulation of neuron death	GO:1901215	98	0.014
positive regulation of neuron projection regeneration	GO:0070572	2	0.013
regulation of transmembrane transport	GO:0034762	128	0.013
post mating behavior	GO:0045297	3	0.013
regulation of ral gtpase activity	GO:0032315	4	0.013
male genitalia morphogenesis	GO:0048808	4	0.013
small molecule catabolic process	GO:0044282	71	0.013
maintenance of location	GO:0051235	89	0.013
lateral line system development	GO:0048925	1	0.013
mammary gland alveolus development	GO:0060749	22	0.013
gtp metabolic process	GO:0046039	144	0.013
ral protein signal transduction	GO:0032484	2	0.013
positive regulation of hydrolase activity	GO:0051345	148	0.013
positive regulation of lymphocyte mediated immunity	GO:0002708	62	0.013
positive regulation of nucleotide catabolic process	GO:0030813	88	0.013
urogenital system development	GO:0001655	261	0.013
positive regulation of canonical wnt signaling pathway	GO:0090263	29	0.013
syncytium formation by plasma membrane fusion	GO:0000768	42	0.012
negative regulation of nervous system development	GO:0051961	156	0.012
positive regulation of lymphocyte differentiation	GO:0045621	61	0.012
purine ribonucleoside monophosphate catabolic process	GO:0009169	57	0.012
gtp catabolic process	GO:0006184	143	0.012
habituation	GO:0046959	3	0.012
establishment of organelle localization	GO:0051656	122	0.012
regulation of synaptic plasticity	GO:0048167	87	0.012
dna dependent dna replication maintenance of fidelity	GO:0045005	3	0.012
telencephalon development	GO:0021537	186	0.012
protein localization to membrane	GO:0072657	108	0.012
cell adhesion	GO:0007155	329	0.012
multi organism reproductive behavior	GO:0044705	29	0.012
dna dependent dna replication	GO:0006261	24	0.012
cellular ion homeostasis	GO:0006873	165	0.012
regulation of hormone levels	GO:0010817	211	0.012
positive regulation of leukocyte differentiation	GO:1902107	86	0.012
response to radiation	GO:0009314	165	0.012
t cell activation	GO:0042110	289	0.012
regulation of lymphocyte differentiation	GO:0045619	107	0.012
positive regulation of vasoconstriction	GO:0045907	4	0.012
sodium ion transport	GO:0006814	73	0.012
long chain fatty acid transport	GO:0015909	15	0.012
translation	GO:0006412	93	0.012
interleukin 10 secretion	GO:0072608	4	0.011
positive regulation of cellular catabolic process	GO:0031331	148	0.011
alpha beta t cell activation	GO:0046631	91	0.011
germ cell development	GO:0007281	185	0.011	Fly
regulation of neuron apoptotic process	GO:0043523	122	0.011
single fertilization	GO:0007338	82	0.011
cellular amine metabolic process	GO:0044106	44	0.011	Fly
regulation of cellular amine metabolic process	GO:0033238	20	0.011	Fly
regulation of canonical wnt signaling pathway	GO:0060828	82	0.011
reactive oxygen species metabolic process	GO:0072593	84	0.011
positive regulation of ion transport	GO:0043270	65	0.011
lipid transport	GO:0006869	98	0.011
sensory system development	GO:0048880	3	0.011
negative regulation of cellular amino acid metabolic process	GO:0045763	0	0.011
cytokine production involved in immune response	GO:0002367	34	0.011
mrna catabolic process	GO:0006402	22	0.011
determination of left right symmetry	GO:0007368	80	0.011
regulation of organic acid transport	GO:0032890	16	0.011
biomineral tissue development	GO:0031214	64	0.011
multicellular organismal response to stress	GO:0033555	62	0.011
protein modification by small protein conjugation	GO:0032446	187	0.011
positive regulation of homeostatic process	GO:0032846	64	0.010
regulation of ion transport	GO:0043269	215	0.010
regulation of secretion by cell	GO:1903530	249	0.010
intracellular protein transport	GO:0006886	204	0.010
negative regulation of neuron apoptotic process	GO:0043524	92	0.010
maternal placenta development	GO:0001893	20	0.010
regulation of neuron differentiation	GO:0045664	281	0.010
positive regulation of cytokine production involved in immune response	GO:0002720	19	0.010
regulation of nucleoside metabolic process	GO:0009118	130	0.010
cellular polysaccharide metabolic process	GO:0044264	38	0.010
cellular carbohydrate metabolic process	GO:0044262	119	0.010
regulation of mrna processing	GO:0050684	41	0.010	Mouse
ubiquitin dependent smad protein catabolic process	GO:0030579	2	0.010
b cell activation	GO:0042113	161	0.010
actin filament organization	GO:0007015	113	0.010
protein alkylation	GO:0008213	81	0.010
monosaccharide metabolic process	GO:0005996	106	0.010
myelination	GO:0042552	74	0.010

Slc39a7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
connective tissue disease	DOID:65	0.036
musculoskeletal system disease	DOID:17	0.036
bone disease	DOID:0080001	0.036
disease of anatomical entity	DOID:7	0.036
bone development disease	DOID:0080006	0.036
cancer	DOID:162	0.033
gastrointestinal system cancer	DOID:3119	0.033
large intestine cancer	DOID:5672	0.033
disease of cellular proliferation	DOID:14566	0.033
intestinal cancer	DOID:10155	0.033
organ system cancer	DOID:0050686	0.033
colorectal cancer	DOID:9256	0.033
colon cancer	DOID:219	0.033
central nervous system disease	DOID:331	0.027
nervous system disease	DOID:863	0.027
osteochondrodysplasia	DOID:2256	0.022
muscular disease	DOID:0080000	0.020
muscle tissue disease	DOID:66	0.020
neurodegenerative disease	DOID:1289	0.018
colon carcinoma	DOID:1520	0.014
physical disorder	DOID:0080015	0.014
osteogenesis imperfecta	DOID:12347	0.013
motor neuron disease	DOID:231	0.011
carbohydrate metabolic disorder	DOID:2978	0.010
disease of metabolism	DOID:0014667	0.010
inherited metabolic disorder	DOID:655	0.010

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