Mus musculus

21 known processes

Smad6

MAD homolog 6 (Drosophila)

(Aliases: Madh6)

Smad6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
bmp signaling pathwayGO:0030509931.000
Human Mouse Fly
mesenchyme developmentGO:00604851520.999
Mouse
heart morphogenesisGO:00030071780.998
Mouse
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.996
Human Mouse Fly
regulation of tight junction assemblyGO:200081020.996
renal system developmentGO:00720012250.995
digestive tract developmentGO:00485651900.995
Mouse Fly
urogenital system developmentGO:00016552610.995
blood vessel morphogenesisGO:00485142850.994
Mouse
kidney developmentGO:00018222130.993
regulation of muscle tissue developmentGO:1901861970.993
Mouse
digestive tract morphogenesisGO:00485461470.993
Mouse Fly
cardiac septum developmentGO:0003279590.993
Mouse
outflow tract morphogenesisGO:0003151530.992
cellular response to growth factor stimulusGO:00713631970.992
Human Mouse Fly
response to growth factorGO:00708481980.992
Human Mouse Fly
negative regulation of bmp signaling pathwayGO:0030514350.991
Human Mouse
cardiac septum morphogenesisGO:0060411460.990
Mouse
nephron morphogenesisGO:0072028690.990
Mouse
ventricular septum developmentGO:0003281420.988
Mouse
cardiac muscle tissue developmentGO:00487381300.988
Mouse
ossificationGO:00015032160.988
Mouse
nephron tubule morphogenesisGO:0072078680.987
Mouse
digestive system developmentGO:00551232000.986
Mouse Fly
endocardial cushion developmentGO:0003197260.986
Mouse
stem cell proliferationGO:00720891170.985
cellular response to transforming growth factor beta stimulusGO:0071560880.984
Human Mouse Fly
transforming growth factor beta receptor signaling pathwayGO:0007179710.984
Human Mouse Fly
cardiac chamber morphogenesisGO:0003206930.983
Mouse
skeletal system morphogenesisGO:00487052030.982
Mouse
cell junction assemblyGO:0034329520.982
atrioventricular valve morphogenesisGO:0003181130.982
Mouse
cardiac chamber developmentGO:00032051080.981
Mouse
camera type eye developmentGO:00430102660.981
Mouse
stem cell maintenanceGO:00198271300.981
Fly
cardiocyte differentiationGO:0035051870.979
Mouse
epithelial to mesenchymal transition involved in endocardial cushion formationGO:0003198100.978
Mouse
ventricular septum morphogenesisGO:0060412270.975
Mouse
cell fate commitment involved in formation of primary germ layerGO:0060795260.973
Mouse
stem cell differentiationGO:00488632680.971
Mouse Fly
regulation of organ morphogenesisGO:20000271440.968
Mouse
stem cell developmentGO:00488642190.968
Mouse Fly
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:00900921120.966
Human Mouse Fly
embryonic heart tube morphogenesisGO:0003143510.966
Mouse
nephron developmentGO:00720061090.965
Mouse
mapk cascadeGO:00001652810.965
Mouse
regulation of cell morphogenesis involved in differentiationGO:00107691510.963
Mouse
regulation of stem cell proliferationGO:0072091780.961
muscle tissue developmentGO:00605373080.961
Mouse
negative regulation of ossificationGO:0030279490.957
Mouse
muscle cell differentiationGO:00426922610.952
regulation of ossificationGO:00302781120.949
Mouse
negative regulation of neuron differentiationGO:00456651010.949
cardiac ventricle developmentGO:0003231830.948
Mouse
embryonic skeletal system developmentGO:00487061200.947
Mouse
striated muscle tissue developmentGO:00147062930.946
Mouse
wnt signaling pathwayGO:00160551880.944
osteoblast developmentGO:0002076170.942
Mouse
regulation of cell activationGO:00508652890.939
regulation of bmp signaling pathwayGO:0030510600.939
Human Mouse
neuron projection guidanceGO:00974851410.935
Mouse Fly
renal tubule morphogenesisGO:0061333720.934
Mouse Fly
embryonic organ morphogenesisGO:00485622760.934
Mouse
regulation of mapk cascadeGO:00434082480.933
chondrocyte differentiationGO:0002062720.933
Mouse
morphogenesis of a branching epitheliumGO:00611381930.932
Mouse
regulation of cartilage developmentGO:0061035440.932
Mouse
embryonic skeletal system morphogenesisGO:0048704910.929
Mouse
regulation of sequence specific dna binding transcription factor activityGO:00510901060.928
epithelial cell proliferationGO:00506731740.928
Mouse
epithelial tube morphogenesisGO:00605623030.925
Mouse Fly
embryonic placenta developmentGO:0001892980.922
respiratory system developmentGO:00605411900.921
Mouse
determination of heart left right asymmetryGO:0061371480.919
Mouse
regionalizationGO:00030023370.918
Human Mouse Fly
cardiac muscle tissue morphogenesisGO:0055008440.918
Mouse
regulation of cellular response to growth factor stimulusGO:0090287820.917
Human Mouse Fly
ureteric bud developmentGO:0001657940.917
retinal blood vessel morphogenesisGO:006130430.917
regulation of neuron differentiationGO:00456642810.915
heart valve formationGO:0003188100.914
Mouse
forebrain developmentGO:00309003020.914
endocardial cell differentiationGO:006095640.913
Mouse
lung developmentGO:00303241640.912
Mouse
mesoderm morphogenesisGO:0048332640.912
Mouse
muscular septum morphogenesisGO:000315040.911
somite developmentGO:0061053810.910
Mouse
nephron epithelium developmentGO:0072009920.910
Mouse
ubiquitin dependent smad protein catabolic processGO:003057920.908
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.905
positive regulation of cell developmentGO:00107202370.904
Mouse
positive regulation of nervous system developmentGO:00519622210.904
hindbrain developmentGO:00309021280.903
Mouse
axon guidanceGO:00074111410.902
Mouse Fly
cytoplasmic transportGO:00164822340.901
Mouse
determination of left right symmetryGO:0007368800.900
Mouse
endocrine system developmentGO:0035270980.898
Mouse
negative regulation of cell proliferationGO:00082852960.898
Human Mouse
heart valve morphogenesisGO:0003179210.897
Mouse
regulation of vasculature developmentGO:1901342880.893
epithelial tube formationGO:00721751300.887
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512260.887
Human Fly
hormone secretionGO:00468791280.886
Mouse
endodermal cell fate commitmentGO:0001711120.886
mitral valve developmentGO:000317440.886
morphogenesis of embryonic epitheliumGO:00163311590.885
hair follicle developmentGO:0001942850.885
Mouse
axonogenesisGO:00074092740.884
Mouse Fly
pigment accumulationGO:004347610.883
Worm
muscle cell developmentGO:00550011330.881
circulatory system processGO:00030131970.880
Mouse
mitral valve morphogenesisGO:000318340.880
negative regulation of fat cell differentiationGO:0045599360.877
response to transforming growth factor betaGO:0071559880.877
Human Mouse Fly
stress activated protein kinase signaling cascadeGO:0031098810.876
respiratory tube developmentGO:00303231670.874
Mouse
endocardial cushion morphogenesisGO:0003203180.871
Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101610.871
Human Mouse Fly
canonical wnt signaling pathwayGO:00600701300.871
negative regulation of nervous system developmentGO:00519611560.871
Fly
mesenchymal cell proliferationGO:0010463440.870
angiogenesisGO:00015252010.869
t cell activationGO:00421102890.867
Mouse
nephron tubule developmentGO:0072080840.866
Mouse
nephron epithelium morphogenesisGO:0072088680.860
Mouse
limb morphogenesisGO:00351081490.858
regulation of wnt signaling pathwayGO:00301111230.855
morphogenesis of an epithelial sheetGO:0002011270.854
endodermal cell fate specificationGO:000171440.849
epithelial to mesenchymal transitionGO:0001837470.846
Mouse
kidney epithelium developmentGO:00720731210.842
heart formationGO:0060914160.842
regulation of cell adhesionGO:00301551540.842
Mouse
sensory organ morphogenesisGO:00905962420.838
gland developmentGO:00487323300.836
Mouse
regulation of cardiac muscle tissue developmentGO:0055024310.833
wnt signaling pathway involved in somitogenesisGO:009024440.832
neural tube formationGO:00018411080.831
negative regulation of canonical wnt signaling pathwayGO:0090090510.831
autonomic nervous system developmentGO:0048483430.826
paraxial mesoderm morphogenesisGO:0048340100.825
Mouse
embryonic digit morphogenesisGO:0042733560.825
striated muscle cell developmentGO:00550021250.824
axial mesoderm formationGO:004832030.823
blood circulationGO:00080151950.823
Mouse
appendage morphogenesisGO:00351071490.822
Fly
positive regulation of stem cell proliferationGO:2000648590.819
regulation of osteoblast differentiationGO:0045667670.819
Mouse
cell junction organizationGO:0034330770.818
mesonephric tubule developmentGO:0072164940.818
artery developmentGO:0060840530.816
Mouse
vascular endothelial growth factor receptor signaling pathwayGO:0048010240.815
nuclear transportGO:00511691390.814
Mouse
lung morphogenesisGO:0060425500.811
embryonic heart tube developmentGO:0035050650.805
Mouse
positive regulation of protein phosphorylationGO:00019342420.804
Mouse
gastrulationGO:00073691160.803
Mouse
mesonephros developmentGO:0001823970.803
morphogenesis of a branching structureGO:00017632030.802
Mouse
jnk cascadeGO:0007254720.800
ureteric bud morphogenesisGO:0060675620.795
Mouse
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.792
mesodermal cell fate commitmentGO:0001710170.791
Mouse
negative regulation of cell developmentGO:00107211690.790
positive regulation of mesenchymal cell proliferationGO:0002053330.788
embryonic limb morphogenesisGO:00303261260.786
somatic stem cell maintenanceGO:0035019470.786
cardiac muscle cell differentiationGO:0055007690.786
peptidyl amino acid modificationGO:00181933360.786
Mouse
regulation of neural precursor cell proliferationGO:2000177700.783
bundle of his developmentGO:000316640.776
aorta morphogenesisGO:0035909220.772
mesenchymal cell differentiationGO:00487621070.770
Mouse
bone mineralizationGO:0030282540.770
organ growthGO:00352651170.769
Mouse
neural tube closureGO:0001843900.769
intracellular protein transportGO:00068862040.768
Mouse
endocardial cushion to mesenchymal transition involved in heart valve formationGO:000319940.768
ventricular cardiac muscle tissue developmentGO:0003229380.766
Mouse
renal tubule developmentGO:0061326870.764
Mouse Fly
regulation of chondrocyte differentiationGO:0032330330.763
Mouse
mesonephric tubule morphogenesisGO:0072171630.759
Mouse
paraxial mesoderm developmentGO:0048339180.748
Mouse
regulation of epithelial cell proliferationGO:00506781410.748
Mouse
endothelial cell differentiationGO:0045446410.747
Mouse
central nervous system neuron differentiationGO:00219531620.743
regulation of neuron projection developmentGO:00109751690.742
regulation of heart morphogenesisGO:2000826220.741
Mouse
embryonic appendage morphogenesisGO:00351131260.737
metanephric mesenchyme morphogenesisGO:007213340.737
Mouse
odontogenesisGO:0042476780.736
telencephalon developmentGO:00215371860.731
trachea cartilage morphogenesisGO:006053540.730
cell cell junction organizationGO:0045216720.727
cardiac ventricle morphogenesisGO:0003208500.723
Mouse
heart valve developmentGO:0003170230.723
Mouse
palate developmentGO:0060021760.722
Mouse
developmental growth involved in morphogenesisGO:00605601380.722
Fly
regulation of embryonic developmentGO:0045995710.722
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.721
Human Mouse Fly
regulation of hippo signalingGO:003533010.721
kidney morphogenesisGO:0060993830.720
Mouse
mesoderm formationGO:0001707620.719
Mouse
tube formationGO:00351481400.719
atrioventricular valve developmentGO:0003171150.717
Mouse
regulation of mesenchymal cell proliferationGO:0010464370.716
mesenchymal cell developmentGO:0014031930.715
Mouse
metanephros developmentGO:0001656790.715
Mouse
polarity specification of proximal distal axisGO:001008520.713
cardiac muscle cell developmentGO:0055013390.711
cardiac endothelial cell differentiationGO:000334840.710
Mouse
cell proliferation involved in heart morphogenesisGO:0061323150.709
Mouse
appendage developmentGO:00487361660.706
Fly
aortic valve morphogenesisGO:000318040.705
cell cell signaling involved in cell fate commitmentGO:0045168350.704
mesenchyme morphogenesisGO:0072132320.703
Mouse
protein localization to nucleusGO:00345041210.703
Mouse
positive regulation of transferase activityGO:00513471670.698
formation of primary germ layerGO:0001704770.697
Mouse
erythrocyte differentiationGO:0030218880.695
Mouse
cardiac atrium developmentGO:0003230240.694
mesoderm developmentGO:00074981000.692
Mouse
primary neural tube formationGO:0014020950.688
cell fate specificationGO:0001708720.688
foregut morphogenesisGO:0007440120.688
Mouse
neural crest cell differentiationGO:0014033540.687
Mouse
single organismal cell cell adhesionGO:00163371310.686
Mouse
wnt signaling pathway involved in forebrain neuroblast divisionGO:002187420.686
planar cell polarity pathway involved in ventricular septum morphogenesisGO:006134820.682
single organism cell adhesionGO:00986021560.679
Mouse
neural crest cell migrationGO:0001755320.678
segmentationGO:0035282930.678
Mouse
placenta developmentGO:00018901400.672
endocardial cushion formationGO:0003272130.671
Mouse
branching morphogenesis of an epithelial tubeGO:00487541590.671
Mouse
regulation of jnk cascadeGO:0046328620.669
regulation of intracellular protein transportGO:0033157820.669
Mouse
neural precursor cell proliferationGO:00613511210.667
positive regulation of neuron differentiationGO:00456661410.665
negative regulation of catenin import into nucleusGO:003541420.664
notochord developmentGO:0030903200.663
single organism nuclear importGO:1902593950.657
Mouse
syncytiotrophoblast cell differentiation involved in labyrinthine layer developmentGO:006071520.656
negative regulation of osteoblast differentiationGO:0045668300.654
Mouse
myeloid cell differentiationGO:00300992330.653
Mouse
regulation of lymphocyte activationGO:00512492400.651
planar cell polarity pathway involved in cardiac muscle tissue morphogenesisGO:006135020.647
positive regulation of map kinase activityGO:0043406840.645
regulation of epithelial to mesenchymal transitionGO:0010717220.644
Mouse
regulation of cell migrationGO:00303342190.643
cartilage developmentGO:00512161400.642
Mouse
planar cell polarity pathway involved in pericardium morphogenesisGO:006135420.642
pituitary gland developmentGO:0021983380.634
regulation of protein kinase activityGO:00458592320.633
embryonic camera type eye developmentGO:0031076360.633
kidney mesenchyme morphogenesisGO:007213140.632
Mouse
regulation of catenin import into nucleusGO:003541250.631
cardiac atrium morphogenesisGO:0003209230.630
cell adhesionGO:00071553290.629
Human Mouse
negative regulation of cardiac chamber morphogenesisGO:190122020.627
fat cell differentiationGO:00454441600.623
Human
labyrinthine layer blood vessel developmentGO:0060716210.623
retinal ganglion cell axon guidanceGO:0031290180.621
Fly
negative regulation of immune system processGO:00026832090.620
notochord formationGO:001402850.619
positive regulation of stem cell differentiationGO:2000738230.618
Mouse
positive regulation of secondary heart field cardioblast proliferationGO:007251340.618
myeloid cell homeostasisGO:00022621140.617
Mouse
atrial septum primum morphogenesisGO:000328930.615
cell differentiation involved in embryonic placenta developmentGO:0060706260.612
septum primum developmentGO:000328440.611
regulation of transferase activityGO:00513382630.610
regulation of protein targetingGO:1903533610.610
Mouse
planar cell polarity pathway involved in outflow tract morphogenesisGO:006134720.610
regulation of cardiac muscle tissue growthGO:0055021260.608
clara cell differentiationGO:006048640.606
skeletal muscle satellite cell maintenance involved in skeletal muscle regenerationGO:001483430.599
establishment of planar polarity involved in neural tube closureGO:0090177150.598
forebrain regionalizationGO:0021871250.598
amine metabolic processGO:0009308450.597
negative regulation of molecular functionGO:00440922580.595
limb developmentGO:00601731660.594
negative regulation of wnt signaling pathwayGO:0030178730.588
embryonic digestive tract morphogenesisGO:0048557170.588
neural tube developmentGO:00219151600.586
midbrain developmentGO:0030901350.586
Mouse
positive regulation of bmp signaling pathwayGO:0030513230.585
embryonic epithelial tube formationGO:00018381300.584
positive regulation of protein serine threonine kinase activityGO:00719021060.583
skeletal system developmentGO:00015013560.578
Mouse
leukocyte differentiationGO:00025213420.574
forebrain neuron differentiationGO:0021879520.573
stress activated mapk cascadeGO:0051403800.568
regulation of stress activated mapk cascadeGO:0032872690.566
blastocyst developmentGO:0001824800.566
cell proliferation involved in outflow tract morphogenesisGO:006132540.562
lens development in camera type eyeGO:0002088620.562
Mouse
cell fate determinationGO:0001709320.555
t cell proliferationGO:00420981200.554
tricuspid valve developmentGO:000317530.554
cellular amino acid metabolic processGO:00065201030.551
regulation of ureteric bud formationGO:007210630.551
developmental inductionGO:0031128340.550
peptidyl tyrosine phosphorylationGO:00181081430.550
somitogenesisGO:0001756690.549
Mouse
positive regulation of cardiac muscle tissue growthGO:0055023150.547
commissural neuron axon guidanceGO:007167980.544
smad protein signal transductionGO:0060395210.540
Mouse
regulation of map kinase activityGO:00434051200.538
neuroblast proliferationGO:0007405490.537
inner ear morphogenesisGO:00424721010.537
regulation of osteoblast proliferationGO:0033688150.536
Mouse
lymphocyte proliferationGO:00466511640.536
regulation of cell cycleGO:00517262810.532
cardiac muscle tissue growthGO:0055017370.532
Mouse
cardiac epithelial to mesenchymal transitionGO:0060317180.531
Mouse
muscle system processGO:00030121410.530
Mouse
negative regulation of epithelial cell proliferationGO:0050680640.530
positive regulation of cardiac muscle tissue developmentGO:0055025190.529
connective tissue developmentGO:00614481790.525
Mouse
cardiac muscle cell proliferationGO:0060038310.524
Mouse
nephric duct formationGO:007217940.524
progesterone secretionGO:004270110.523
positive regulation of epithelial cell proliferationGO:0050679680.523
paraxial mesodermal cell differentiationGO:004834220.521
nephrogenic mesenchyme morphogenesisGO:007213420.519
Mouse
striated muscle cell proliferationGO:0014855390.519
Mouse
regulation of cellular component biogenesisGO:00440871810.518
Human Fly
regulation of cell substrate adhesionGO:0010810730.518
mesonephric epithelium developmentGO:0072163940.513
pancreas developmentGO:0031016570.513
Mouse
regulation of t cell proliferationGO:0042129920.510
insulin secretionGO:0030073890.509
Mouse
regulation of canonical wnt signaling pathwayGO:0060828820.508
skeletal muscle fiber developmentGO:0048741580.506
cardiac right atrium morphogenesisGO:000321330.504
myoblast differentiationGO:0045445520.500
somite rostral caudal axis specificationGO:0032525130.498
Mouse
his purkinje system developmentGO:000316440.497
positive regulation of heart growthGO:0060421180.495
ear developmentGO:00435832000.494
regulation of striated muscle cell differentiationGO:0051153810.493
central nervous system vasculogenesisGO:002200930.493
positive regulation of protein modification processGO:00314012990.492
Mouse
regulation of cardiac muscle cell proliferationGO:0060043230.490
chemotaxisGO:00069352470.485
Mouse Fly
positive regulation of ureteric bud formationGO:007210730.485
positive regulation of striated muscle tissue developmentGO:0045844310.485
metencephalon developmentGO:0022037890.484
positive regulation of angiogenesisGO:0045766460.481
apical junction assemblyGO:0043297150.480
cell fate commitmentGO:00451652100.477
Mouse
regulation of cellular amine metabolic processGO:0033238200.476
biomineral tissue developmentGO:0031214640.476
positive regulation of protein kinase activityGO:00458601440.475
negative regulation of wnt signaling pathway involved in heart developmentGO:000330840.474
epithelial cell morphogenesisGO:0003382410.473
retina vasculature development in camera type eyeGO:0061298170.471
forebrain neuron fate commitmentGO:0021877130.470
negative regulation of prostatic bud formationGO:006068640.469
positive regulation of cartilage developmentGO:0061036180.467
Mouse
ear morphogenesisGO:00424711180.466
forebrain morphogenesisGO:0048853170.466
planar cell polarity pathway involved in cardiac right atrium morphogenesisGO:006134920.465
regulation of cell proliferation involved in heart morphogenesisGO:2000136150.463
Mouse
regulation of gliogenesisGO:0014013500.463
negative regulation of cell fate specificationGO:000999640.460
negative regulation of hepatocyte differentiationGO:007036710.459
renal vesicle inductionGO:007203430.459
smoothened signaling pathwayGO:00072241050.458
mammary gland morphogenesisGO:0060443540.458
gonad developmentGO:00084061410.452
neural crest cell developmentGO:0014032480.451
labyrinthine layer developmentGO:0060711490.451
cell migration involved in gastrulationGO:0042074130.450
specification of organ identityGO:0010092300.449
aorta developmentGO:0035904230.448
positive regulation of cell adhesionGO:0045785800.447
Mouse
cochlea morphogenesisGO:0090103220.446
positive regulation of protein catabolic processGO:0045732600.441
gastrulation with mouth forming secondGO:0001702290.441
Mouse
wnt signaling pathway planar cell polarity pathwayGO:0060071270.440
lymphocyte differentiationGO:00300982420.440
axial mesoderm morphogenesisGO:004831950.440
protein modification by small protein conjugationGO:00324461870.439
positive regulation of jun kinase activityGO:0043507300.438
response to monosaccharideGO:0034284670.437
Mouse
cochlea developmentGO:0090102350.433
regulation of angiogenesisGO:0045765810.432
regulation of fat cell differentiationGO:0045598810.428
ameboidal type cell migrationGO:00016671280.428
sympathetic nervous system developmentGO:0048485220.427
regulation of cardiac cell fate specificationGO:200004310.426
planar cell polarity pathway involved in neural tube closureGO:0090179140.426
regulation of leukocyte proliferationGO:00706631210.425
nephrogenic mesenchyme developmentGO:007207630.425
Mouse
epidermis developmentGO:00085441870.419
Mouse
regulation of t cell activationGO:00508631700.417
mesendoderm developmentGO:004838230.417
blastocyst formationGO:0001825330.416
spinal cord developmentGO:0021510810.416
skeletal muscle organ developmentGO:00605381630.416
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787250.413
negative regulation of growthGO:0045926990.412
Fly
regulation of peptide hormone secretionGO:0090276750.412
cellular response to fibroblast growth factor stimulusGO:0044344470.411
regulation of bindingGO:00510981110.409
Mouse
epithelial cell developmentGO:00020641590.408
mammary placode formationGO:006059640.403
regulation of stem cell differentiationGO:2000736500.402
Mouse
retina development in camera type eyeGO:00600411190.400
protein import into nucleusGO:0006606950.399
Mouse
negative regulation of defense responseGO:0031348770.398
Mouse
endothelium developmentGO:0003158450.396
Mouse
positive regulation of chondrocyte differentiationGO:0032332130.396
Mouse
bone developmentGO:00603481200.396
Mouse
tongue developmentGO:0043586180.396
tendon formationGO:003599240.395
regulation of cardiac chamber morphogenesisGO:190121920.394
peptide transportGO:00158331330.394
Mouse
regulation of kidney developmentGO:0090183400.390
limbic system developmentGO:0021761720.389
endoderm formationGO:0001706200.388
Mouse
endochondral bone morphogenesisGO:0060350500.388
regulation of chorionic trophoblast cell proliferationGO:190138210.386
embryonic eye morphogenesisGO:0048048290.385
regulation of establishment of planar polarityGO:0090175280.385
odontogenesis of dentin containing toothGO:0042475660.383
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100430.383
Mouse
cerebellum vasculature developmentGO:006130010.382
formation of radial glial scaffoldsGO:002194340.378
regulation of vascular endothelial growth factor receptor signaling pathwayGO:0030947140.375
bone morphogenesisGO:0060349780.373
neural tube patterningGO:0021532430.372
tube closureGO:0060606910.369
positive regulation of cell morphogenesis involved in differentiationGO:0010770720.369
Mouse
negative regulation of phosphorylationGO:00423261660.369
Human Mouse
hepaticobiliary system developmentGO:0061008670.367
Mouse
cell differentiation involved in kidney developmentGO:0061005330.366
embryonic nail plate morphogenesisGO:003588030.365
regulation of cellular amino acid metabolic processGO:000652150.364
nucleocytoplasmic transportGO:00069131390.363
Mouse
positive regulation of neuroblast proliferationGO:0002052190.363
leukocyte proliferationGO:00706611720.362
myeloid leukocyte differentiationGO:00025731190.362
liver developmentGO:0001889660.362
Mouse
cerebellum vasculature morphogenesisGO:006130110.361
regulation of heart growthGO:0060420310.360
forebrain generation of neuronsGO:0021872630.360
epithelial cell differentiation involved in kidney developmentGO:0035850230.359
cerebral cortex developmentGO:0021987860.359
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulusGO:190152270.357
Mouse
heart trabecula formationGO:0060347140.357
negative regulation of embryonic developmentGO:0045992220.356
positive regulation of mapk cascadeGO:00434101700.355
establishment of planar polarity of embryonic epitheliumGO:0042249160.354
cellular ketone metabolic processGO:0042180840.352
body morphogenesisGO:0010171450.350
regulation of kinase activityGO:00435492490.350
metanephric nephron developmentGO:0072210340.350
regulation of lymphocyte proliferationGO:00506701170.348
skeletal muscle cell differentiationGO:0035914660.348
regulation of protein catabolic processGO:00421761080.346
negative regulation of mesenchymal cell proliferationGO:007220130.344
regulation of peptidyl tyrosine phosphorylationGO:0050730930.344
positive regulation of cellular amino acid metabolic processGO:004576430.343
oligodendrocyte differentiationGO:0048709530.343
protein importGO:00170381010.341
Mouse
cardiac cell developmentGO:0055006410.339
organ inductionGO:0001759210.337
metanephric nephron epithelium developmentGO:0072243190.337
coronary vasculature developmentGO:0060976120.332
chondrocyte developmentGO:0002063240.331
olfactory lobe developmentGO:0021988320.330
cell cell junction assemblyGO:0007043270.327
renal vesicle developmentGO:0072087170.327
negative regulation of execution phase of apoptosisGO:190011840.327
cell surface receptor signaling pathway involved in heart developmentGO:0061311150.326
heart growthGO:0060419450.324
Mouse
negative regulation of planar cell polarity pathway involved in pericardium morphogenesisGO:200016610.324
atrioventricular canal developmentGO:003630250.323
Mouse
positive regulation of muscle tissue developmentGO:1901863320.323
peptide hormone secretionGO:00300721090.323
Mouse
immune effector processGO:00022523210.323
axis elongation involved in somitogenesisGO:009024540.322
metanephric tubule developmentGO:0072170180.321
regulation of nucleocytoplasmic transportGO:0046822730.321
Mouse
embryonic digestive tract developmentGO:0048566270.320
skeletal muscle tissue regenerationGO:0043403200.319
epithelial cell differentiation involved in mammary gland alveolus developmentGO:006103040.316
maintenance of cell numberGO:009872730.316
atrial septum developmentGO:0003283120.315
muscle contractionGO:00069361010.313
Mouse
negative regulation of cartilage developmentGO:0061037170.313
glial cell differentiationGO:00100011310.311
positive regulation of ossificationGO:0045778470.310
Mouse

Smad6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.530
cancerDOID:16200.382
organ system cancerDOID:005068600.382