IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Srp68

signal recognition particle 68

(Aliases: MGC38208,2610024I03Rik)

Entrez: 217337
Ensembl: ENSMUSG00000020780
UniProtKB: Q8BMA6

Process Predictions
Disease Predictions

Srp68 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
cellular amino acid metabolic process	GO:0006520	103	0.164
protein modification by small protein conjugation	GO:0032446	187	0.149
translational initiation	GO:0006413	24	0.103
protein modification by small protein conjugation or removal	GO:0070647	207	0.081
protein ubiquitination	GO:0016567	171	0.073
rna processing	GO:0006396	105	0.067
translation	GO:0006412	93	0.060
endomembrane system organization	GO:0010256	147	0.057
response to endoplasmic reticulum stress	GO:0034976	53	0.050
endocytosis	GO:0006897	168	0.050
amino acid activation	GO:0043038	1	0.049
trna aminoacylation for protein translation	GO:0006418	1	0.044
cellular amine metabolic process	GO:0044106	44	0.042
amine metabolic process	GO:0009308	45	0.042
membrane organization	GO:0061024	245	0.041
mrna metabolic process	GO:0016071	84	0.039
trna metabolic process	GO:0006399	11	0.038
dna repair	GO:0006281	107	0.036
regulation of cellular amine metabolic process	GO:0033238	20	0.034
regulation of cellular amino acid metabolic process	GO:0006521	5	0.032
macromolecule catabolic process	GO:0009057	281	0.029
cytoplasmic translational initiation	GO:0002183	3	0.028
positive regulation of protein modification process	GO:0031401	299	0.028
cellular response to dna damage stimulus	GO:0006974	207	0.028
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.027
chromatin modification	GO:0016568	187	0.026
cellular ketone metabolic process	GO:0042180	84	0.026
positive regulation of cellular amine metabolic process	GO:0033240	5	0.025
cellular macromolecule catabolic process	GO:0044265	206	0.025
histone h2a ubiquitination	GO:0033522	3	0.025
dna metabolic process	GO:0006259	303	0.024
cellular nitrogen compound catabolic process	GO:0044270	280	0.024
regulation of translation	GO:0006417	71	0.022
aromatic compound catabolic process	GO:0019439	286	0.022
heterocycle catabolic process	GO:0046700	280	0.022
posttranscriptional regulation of gene expression	GO:0010608	155	0.021
copii coated vesicle budding	GO:0090114	2	0.021
retrograde transport endosome to golgi	GO:0042147	2	0.021
negative regulation of cellular amine metabolic process	GO:0033239	1	0.021
membrane fusion	GO:0061025	38	0.020
golgi vesicle transport	GO:0048193	30	0.020
rna splicing	GO:0008380	54	0.019
histone modification	GO:0016570	159	0.019
response to organonitrogen compound	GO:0010243	246	0.018
synaptic transmission	GO:0007268	329	0.018
intracellular mrna localization	GO:0008298	4	0.017
proteolysis involved in cellular protein catabolic process	GO:0051603	147	0.017
vesicle organization	GO:0016050	60	0.017
negative regulation of cellular component organization	GO:0051129	194	0.017
maintenance of location	GO:0051235	89	0.017
regulation of secretion	GO:0051046	274	0.017
purine containing compound metabolic process	GO:0072521	311	0.017
cytoplasmic transport	GO:0016482	234	0.017
regulation of cellular component biogenesis	GO:0044087	181	0.017
cellular protein catabolic process	GO:0044257	155	0.016
protein catabolic process	GO:0030163	221	0.016
regulation of cellular ketone metabolic process	GO:0010565	66	0.016
multicellular organismal signaling	GO:0035637	91	0.016
intra golgi vesicle mediated transport	GO:0006891	1	0.016
cellular response to lipid	GO:0071396	145	0.015
lymphocyte differentiation	GO:0030098	242	0.015
cation transport	GO:0006812	399	0.015
modification dependent protein catabolic process	GO:0019941	133	0.015
regulation of cell activation	GO:0050865	289	0.015
negative regulation of protein metabolic process	GO:0051248	282	0.015
ribonucleoprotein complex subunit organization	GO:0071826	28	0.014
intracellular protein transport	GO:0006886	204	0.014
protein polymerization	GO:0051258	57	0.014
regulation of organelle organization	GO:0033043	289	0.014
trna aminoacylation	GO:0043039	1	0.014
trna wobble base modification	GO:0002097	2	0.014
regulation of protein complex assembly	GO:0043254	83	0.014
lipid localization	GO:0010876	126	0.014
nucleobase containing small molecule metabolic process	GO:0055086	352	0.014
regulation of mitotic cell cycle	GO:0007346	126	0.013
positive regulation of protein phosphorylation	GO:0001934	242	0.013
response to radiation	GO:0009314	165	0.013
action potential	GO:0001508	78	0.013
regulation of cell division	GO:0051302	76	0.013
purine containing compound catabolic process	GO:0072523	213	0.013
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.013
trna wobble uridine modification	GO:0002098	2	0.013
chromatin organization	GO:0006325	206	0.013
neuronal action potential	GO:0019228	54	0.013
leukocyte differentiation	GO:0002521	342	0.013
nucleotide metabolic process	GO:0009117	332	0.013
protein hydroxylation	GO:0018126	4	0.013
mrna processing	GO:0006397	63	0.013
mitotic cell cycle	GO:0000278	195	0.013
regulation of cell cycle	GO:0051726	281	0.013
organic cyclic compound catabolic process	GO:1901361	295	0.012
mrna splicing via spliceosome	GO:0000398	43	0.012
apoptotic signaling pathway	GO:0097190	306	0.012
transmission of nerve impulse	GO:0019226	76	0.012
dephosphorylation	GO:0016311	129	0.012
cellular response to cadmium ion	GO:0071276	3	0.012
negative regulation of synapse assembly	GO:0051964	3	0.012
molting cycle	GO:0042303	90	0.012
cellular response to nutrient levels	GO:0031669	64	0.012
germ cell development	GO:0007281	185	0.012
regulation of mrna processing	GO:0050684	41	0.012
protein localization to organelle	GO:0033365	185	0.012
spermatid differentiation	GO:0048515	115	0.012
cellular response to organonitrogen compound	GO:0071417	145	0.012
nitrogen compound transport	GO:0071705	271	0.012
b cell activation	GO:0042113	161	0.012
peptidyl amino acid modification	GO:0018193	336	0.011
response to inorganic substance	GO:0010035	96	0.011
ensheathment of neurons	GO:0007272	76	0.011
regulation of protein catabolic process	GO:0042176	108	0.011
spermatogenesis	GO:0007283	284	0.011
cellular protein complex assembly	GO:0043623	116	0.011
response to light stimulus	GO:0009416	135	0.011
ubiquitin dependent protein catabolic process	GO:0006511	129	0.011
protein secretion	GO:0009306	111	0.011
rna splicing via transesterification reactions	GO:0000375	43	0.011
purine ribonucleotide catabolic process	GO:0009154	208	0.011
placenta development	GO:0001890	140	0.011
glial cell differentiation	GO:0010001	131	0.011
cation transmembrane transport	GO:0098655	266	0.011
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.011
negative regulation of intracellular signal transduction	GO:1902532	167	0.011
localization within membrane	GO:0051668	4	0.010
oxidation reduction process	GO:0055114	342	0.010
regulation of lymphocyte activation	GO:0051249	240	0.010
meiosis i	GO:0007127	60	0.010
nucleoside phosphate metabolic process	GO:0006753	338	0.010
cellular response to cytokine stimulus	GO:0071345	189	0.010
negative regulation of protein modification process	GO:0031400	163	0.010
myelination	GO:0042552	74	0.010
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	43	0.010
cytokine production	GO:0001816	319	0.010
organophosphate catabolic process	GO:0046434	232	0.010
neurotransmitter transport	GO:0006836	76	0.010
regulation of mrna metabolic process	GO:1903311	43	0.010

Srp68 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
neuropathy	DOID:870	0.042
nervous system disease	DOID:863	0.042
disease of anatomical entity	DOID:7	0.042
neuromuscular disease	DOID:440	0.028
sensory system disease	DOID:0050155	0.024
retinal degeneration	DOID:8466	0.024
eye and adnexa disease	DOID:1492	0.024
retinal disease	DOID:5679	0.024
eye disease	DOID:5614	0.024
central nervous system disease	DOID:331	0.016
charcot marie tooth disease	DOID:10595	0.013
neurodegenerative disease	DOID:1289	0.011
immune system disease	DOID:2914	0.010

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network