Mus musculus

0 known processes

Tcra

T-cell receptor alpha chain

(Aliases: Tcralpha,OTTMUSG00000015028)

Tcra biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of mast cell activationGO:0033003211.000
cd4 positive cd25 positive alpha beta regulatory t cell differentiationGO:000236140.996
positive regulation of isotype switching to igg isotypesGO:004830470.996
positive regulation of regulatory t cell differentiationGO:004559140.995
regulation of b cell differentiationGO:0045577230.994
t cell receptor signaling pathwayGO:0050852460.991
somatic diversification of immunoglobulins involved in immune responseGO:0002208360.980
positive regulation of t cell mediated cytotoxicityGO:0001916150.980
t cell differentiation in thymusGO:0033077770.979
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.969
t cell activationGO:00421102890.958
regulation of toll like receptor 4 signaling pathwayGO:003414340.956
positive regulation of gamma delta t cell differentiationGO:004558860.954
regulation of toll like receptor 2 signaling pathwayGO:003413530.951
regulation of tolerance induction dependent upon immune responseGO:000265210.951
positive regulation of type ii hypersensitivityGO:000289440.947
somatic recombination of immunoglobulin gene segmentsGO:0016447420.934
positive regulation of myeloid leukocyte mediated immunityGO:0002888140.930
negative regulation of inflammatory response to antigenic stimulusGO:0002862100.926
positive regulation of isotype switchingGO:0045830150.925
dna recombinationGO:0006310920.921
immunoglobulin mediated immune responseGO:0016064690.909
negative regulation of toll like receptor 2 signaling pathwayGO:003413630.908
leukocyte homeostasisGO:0001776790.880
regulation of isotype switching to igg isotypesGO:0048302100.865
immune response activating signal transductionGO:00027571160.844
somatic diversification of immune receptorsGO:0002200530.843
mast cell activation involved in immune responseGO:0002279200.836
positive regulation of production of molecular mediator of immune responseGO:0002702450.835
dna metabolic processGO:00062593030.833
defense response to bacteriumGO:00427421190.814
negative regulation of leukocyte proliferationGO:0070664460.809
regulation of mast cell activation involved in immune responseGO:0033006170.807
myeloid leukocyte activationGO:0002274830.795
leukocyte differentiationGO:00025213420.790
t cell differentiationGO:00302171740.787
regulation of b cell mediated immunityGO:0002712370.786
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002823230.783
hematopoietic stem cell migrationGO:003570110.779
cellular amine metabolic processGO:0044106440.765
positive regulation of defense response to bacteriumGO:190042610.758
negative regulation of adaptive immune responseGO:0002820250.751
somatic diversification of immunoglobulinsGO:0016445430.749
regulation of tumor necrosis factor productionGO:0032680490.743
metal ion homeostasisGO:00550651890.722
positive regulation of defense responseGO:00313491240.721
myeloid leukocyte cytokine productionGO:0061082120.721
antigen receptor mediated signaling pathwayGO:0050851640.713
regulation of inflammatory responseGO:00507271470.702
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.697
regulation of t cell anergyGO:000266740.691
isotype switching to igg isotypesGO:0048291100.688
extrinsic apoptotic signaling pathwayGO:00971911260.683
regulation of cell activationGO:00508652890.678
endodermal cell fate specificationGO:000171440.663
positive regulation of adaptive immune responseGO:0002821610.663
negative regulation of interleukin 2 biosynthetic processGO:004508530.657
adaptive immune responseGO:00022501550.653
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.644
regulation of phospholipase c activityGO:190027430.619
positive regulation of b cell mediated immunityGO:0002714260.611
antibacterial peptide productionGO:000277820.609
serotonin secretion involved in inflammatory responseGO:000244240.600
positive regulation of cellular amine metabolic processGO:003324050.598
positive regulation of type iii hypersensitivityGO:000180530.595
positive regulation of cytokine productionGO:00018191740.587
peptidyl tyrosine phosphorylationGO:00181081430.586
anatomical structure homeostasisGO:00602491450.570
negative regulation of cell activationGO:00508661110.570
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.551
negative regulation of t cell mediated cytotoxicityGO:000191530.551
mast cell activationGO:0045576270.548
production of molecular mediator of immune responseGO:00024401030.543
learned vocalization behavior or vocal learningGO:009859810.536
regulation of antibacterial peptide biosynthetic processGO:000280810.530
alpha beta t cell differentiationGO:0046632690.521
regulation of alpha beta t cell differentiationGO:0046637350.514
regulation of cellular amine metabolic processGO:0033238200.484
somatic diversification of t cell receptor genesGO:000256850.484
antigen processing and presentation of exogenous antigenGO:0019884260.481
cell fate commitmentGO:00451652100.473
regulation of t cell mediated immunityGO:0002709340.462
immune response activating cell surface receptor signaling pathwayGO:0002429720.457
regulation of cellular ketone metabolic processGO:0010565660.454
fc receptor mediated stimulatory signaling pathwayGO:000243140.453
negative regulation of chronic inflammatory responseGO:000267730.444
v d j recombinationGO:0033151140.440
i kappab kinase nf kappab signalingGO:0007249850.438
production of molecular mediator involved in inflammatory responseGO:0002532210.426
regulation of cd4 positive cd25 positive alpha beta regulatory t cell differentiationGO:003282920.414
regulation of cytokine production involved in immune responseGO:0002718260.408
positive regulation of lymphocyte activationGO:00512511400.401
regulation of isotype switchingGO:0045191220.396
regulation of lymphocyte activationGO:00512492400.395
regulation of type iia hypersensitivityGO:000179640.395
regulation of lymphocyte differentiationGO:00456191070.395
positive regulation of reactive oxygen species biosynthetic processGO:190342820.387
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381430.386
antibacterial humoral responseGO:001973180.378
lymphocyte mediated immunityGO:00024491390.375
filtration diaphragm assemblyGO:003605810.375
positive regulation of cell killingGO:0031343330.373
cellular response to molecule of bacterial originGO:0071219830.371
regulation of dna recombinationGO:0000018340.366
serotonin production involved in inflammatory responseGO:000235140.357
regulation of immunoglobulin mediated immune responseGO:0002889370.356
tyrosine phosphorylation of stat5 proteinGO:004250690.355
regulation of cellular amino acid metabolic processGO:000652150.350
inflammatory responseGO:00069542440.349
b cell activationGO:00421131610.344
b cell activation involved in immune responseGO:0002312500.344
antibacterial peptide biosynthetic processGO:000278020.343
protein autophosphorylationGO:0046777610.343
positive regulation of antibacterial peptide biosynthetic processGO:000696310.342
somatic cell dna recombinationGO:0016444510.341
positive regulation of translational initiationGO:004594840.341
amine metabolic processGO:0009308450.325
cytokine production involved in immune responseGO:0002367340.323
negative regulation of myeloid leukocyte differentiationGO:0002762200.317
activation of immune responseGO:00022531380.312
fc epsilon receptor signaling pathwayGO:003809530.311
regulation of t cell differentiationGO:0045580830.310
positive regulation of lymphocyte anergyGO:000291340.306
thymic t cell selectionGO:0045061220.306
immunoglobulin productionGO:0002377730.299
regulation of tyrosine phosphorylation of stat5 proteinGO:004252280.298
negative regulation of myeloid cell differentiationGO:0045638380.297
tumor necrosis factor productionGO:0032640500.290
regulation of tyrosine phosphorylation of stat proteinGO:0042509200.290
b cell differentiationGO:0030183780.288
positive t cell selectionGO:0043368230.286
t cell selectionGO:0045058340.285
regulation of intracellular transportGO:00323861590.280
interferon gamma productionGO:0032609670.279
t cell proliferationGO:00420981200.278
negative regulation of t cell mediated immunityGO:000271090.277
negative regulation of leukocyte differentiationGO:1902106510.272
regulation of regulated secretory pathwayGO:1903305200.255
positive regulation of podosome assemblyGO:007180330.253
release of sequestered calcium ion into cytosolGO:0051209420.252
myeloid cell homeostasisGO:00022621140.251
alpha beta t cell activationGO:0046631910.250
positive regulation of immunoglobulin mediated immune responseGO:0002891260.248
cellular response to lipidGO:00713961450.246
cellular response to hormone stimulusGO:00328701500.245
lymphocyte differentiationGO:00300982420.244
negative thymic t cell selectionGO:0045060120.244
interleukin 4 productionGO:0032633240.242
regulation of regulatory t cell differentiationGO:004558970.237
regulation of chronic inflammatory response to antigenic stimulusGO:000287430.236
interleukin 6 biosynthetic processGO:0042226120.236
peptidyl amino acid modificationGO:00181933360.232
negative regulation of immune system processGO:00026832090.232
immune response inhibiting signal transductionGO:000276540.232
regulation of t cell receptor signaling pathwayGO:0050856210.232
cell activation involved in immune responseGO:00022631260.231
antigen processing and presentation of exogenous peptide antigenGO:0002478210.229
activation of phospholipase c activityGO:000720220.228
regulation of leukocyte differentiationGO:19021051590.226
negative regulation of leukocyte mediated immunityGO:0002704290.224
regulation of toll like receptor signaling pathwayGO:0034121200.221
positive regulation of lymphocyte mediated immunityGO:0002708620.221
positive regulation of phospholipase activityGO:001051830.219
immune response regulating signaling pathwayGO:00027641250.217
tyrosine phosphorylation of stat proteinGO:0007260230.217
antigen processing and presentation of peptide antigenGO:0048002290.212
antigen processing and presentation of peptide or polysaccharide antigen via mhc class iiGO:0002504170.212
positive regulation of antibacterial peptide productionGO:000280310.211
positive regulation of apoptotic signaling pathwayGO:2001235950.210
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.208
inflammatory response to antigenic stimulusGO:0002437300.207
defense response to other organismGO:00985421970.207
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.204
negative regulation of homeostatic processGO:0032845710.203
lymphocyte homeostasisGO:0002260640.199
compound eye developmentGO:004874910.198
regulation of adaptive immune responseGO:0002819900.198
positive regulation of t cell mediated immunityGO:0002711240.195
chemotaxisGO:00069352470.194
regulation of interleukin 6 productionGO:0032675550.194
regulation of apoptotic signaling pathwayGO:20012331970.193
regulation of antibacterial peptide productionGO:000278610.192
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.192
imitative learningGO:009859610.184
reactive oxygen species metabolic processGO:0072593840.184
protection from non homologous end joining at telomereGO:003184840.183
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.180
cellular response to peptideGO:1901653920.178
interleukin 6 productionGO:0032635580.177
positive regulation of t cell proliferationGO:0042102520.175
negative regulation of map kinase activityGO:0043407340.175
regulation of platelet activationGO:0010543170.174
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.168
positive regulation of exocytosisGO:0045921200.168
response to lipopolysaccharideGO:00324961280.167
lymphocyte activation involved in immune responseGO:0002285930.166
positive regulation of lymphocyte proliferationGO:0050671700.164
regulation of lymphocyte proliferationGO:00506701170.163
growth of symbiont in hostGO:0044117230.163
positive regulation of jun kinase activityGO:0043507300.162
cellular ketone metabolic processGO:0042180840.160
positive regulation of interleukin 6 productionGO:0032755370.159
cellular amino acid metabolic processGO:00065201030.159
chronic inflammatory responseGO:000254490.158
regulation of cytokine productionGO:00018172660.158
regulation of lymphocyte mediated immunityGO:0002706840.157
immune response regulating cell surface receptor signaling pathwayGO:0002768800.155
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:009729620.153
regulation of production of molecular mediator of immune responseGO:0002700650.153
negative regulation of cell adhesion involved in substrate bound cell migrationGO:000693330.151
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.150
regulation of transforming growth factor beta1 productionGO:003290830.149
gamma delta t cell activationGO:0046629130.148
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.145
positive regulation of tyrosine phosphorylation of stat proteinGO:0042531150.145
regulation of type iii hypersensitivityGO:000180330.144
positive regulation of hydrolase activityGO:00513451480.144
integrin mediated signaling pathwayGO:0007229270.144
neutrophil activation involved in immune responseGO:000228380.144
antimicrobial peptide biosynthetic processGO:000277720.143
positive regulation of phospholipase c activityGO:001086320.142
positive regulation of t cell anergyGO:000266940.142
regulation of protein localizationGO:00328802310.141
regulation of humoral immune responseGO:0002920220.141
single organism cell adhesionGO:00986021560.139
positive regulation of cd4 positive cd25 positive alpha beta regulatory t cell differentiationGO:003283120.139
negative regulation of molecular functionGO:00440922580.139
mast cell mediated immunityGO:0002448200.138
telomere maintenance in response to dna damageGO:004324740.138
regulation of cd4 positive alpha beta t cell differentiationGO:0043370210.138
transforming growth factor beta1 productionGO:003290530.137
positive regulation of dna recombinationGO:0045911170.137
positive regulation of chronic inflammatory responseGO:000267840.136
t cell mediated cytotoxicityGO:0001913260.136
positive regulation of stress activated mapk cascadeGO:0032874480.136
positive regulation of immune effector processGO:00026991070.135
b cell mediated immunityGO:0019724710.134
b cell lineage commitmentGO:000232640.133
negative regulation of cellular amino acid metabolic processGO:004576300.133
leukocyte apoptotic processGO:0071887710.133
regulation of peptidyl tyrosine phosphorylationGO:0050730930.132
reactive oxygen species biosynthetic processGO:190340980.129
regulation of mast cell degranulationGO:0043304160.126
positive regulation of hematopoietic stem cell migrationGO:200047310.125
regulation of b cell activationGO:0050864810.125
lymphocyte anergyGO:000224940.124
positive regulation of antigen receptor mediated signaling pathwayGO:005085790.123
pre b cell differentiationGO:000232970.123
regulation of response to woundingGO:19030341890.123
neuroblast fate determinationGO:000740010.121
negative regulation of cellular protein metabolic processGO:00322692470.120
negative regulation of protein metabolic processGO:00512482820.120
regulation of t cell activationGO:00508631700.119
dephosphorylationGO:00163111290.118
negative regulation of insulin receptor signaling pathwayGO:0046627140.116
fc receptor signaling pathwayGO:003809360.115
cytokine mediated signaling pathwayGO:00192211150.114
gamma delta t cell differentiationGO:0042492110.113
regulation of defense responseGO:00313472330.113
isotype switchingGO:0045190360.112
regulation of hydrolase activityGO:00513362460.112
t cell receptor v d j recombinationGO:003315350.110
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.110
cellular response to insulin stimulusGO:0032869780.109
regulation of lymphocyte anergyGO:000291140.109
positive regulation of mast cell activation involved in immune responseGO:0033008100.109
regulation of antigen receptor mediated signaling pathwayGO:0050854290.109
vocal learningGO:004229710.109
regulation of dendritic cell apoptotic processGO:200066830.107
tissue homeostasisGO:00018941150.107
protein localization to nucleusGO:00345041210.106
cellular response to lipopolysaccharideGO:0071222770.106
regulation of immunoglobulin productionGO:0002637420.105
positive regulation of b cell proliferationGO:0030890240.104
multicellular organismal homeostasisGO:00488711640.102
negative regulation of proteolysisGO:0045861740.101
positive regulation of alpha beta t cell differentiationGO:0046638280.100
regulation of myeloid leukocyte differentiationGO:0002761580.100
reactive nitrogen species metabolic processGO:200105700.099
antigen processing and presentation of exogenous peptide antigen via mhc class iGO:004259060.099
regulation of t cell differentiation in thymusGO:0033081240.098
positive regulation of proteolysisGO:0045862850.097
negative regulation of t cell apoptotic processGO:0070233180.097
microtubule based processGO:00070172360.097
positive regulation of t cell differentiationGO:0045582520.097
isotype switching to ige isotypesGO:004828970.096
regulation of inflammatory response to antigenic stimulusGO:0002861210.095
immunoglobulin v d j recombinationGO:003315250.094
cellular ion homeostasisGO:00068731650.094
regulation of interferon gamma productionGO:0032649570.093
regulation of jak stat cascadeGO:0046425340.093
single organismal cell cell adhesionGO:00163371310.093
observational learningGO:009859710.092
immature b cell differentiationGO:0002327100.092
negative regulation of response to woundingGO:1903035770.091
leukocyte migrationGO:00509001240.091
negative regulation of cellular amine metabolic processGO:003323910.090
regulation of t cell mediated cytotoxicityGO:0001914180.089
lymphocyte proliferationGO:00466511640.089
regulation of cd4 positive alpha beta t cell activationGO:2000514240.086
positive regulation of cysteine type endopeptidase activityGO:2001056390.086
regulation of system processGO:00440572000.086
negative regulation of protein modification processGO:00314001630.085
response to reactive oxygen speciesGO:0000302560.085
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557310.085
apoptotic signaling pathwayGO:00971903060.084
neutrophil activationGO:004211990.084
transmembrane receptor protein tyrosine phosphatase signaling pathwayGO:000718510.083
negative regulation of interleukin 5 productionGO:003271440.083
regulation of dendritic cell cytokine productionGO:000273020.083
negative regulation of lymphocyte mediated immunityGO:0002707210.082
negative regulation of interleukin 2 productionGO:003270380.081
negative regulation of peptidase activityGO:0010466460.081
regulation of kinase activityGO:00435492490.080
regulation of jun kinase activityGO:0043506400.080
tumor necrosis factor superfamily cytokine productionGO:0071706510.079
telomere cappingGO:001623340.079
positive regulation of map kinase activityGO:0043406840.079
negative regulation of immune effector processGO:0002698550.078
cellular chemical homeostasisGO:00550822150.078
leukocyte mediated immunityGO:00024431740.078
regulation of map kinase activityGO:00434051200.078
defense response to virusGO:0051607680.078
intrinsic apoptotic signaling pathwayGO:00971931320.077
peptide metabolic processGO:0006518460.077
positive regulation of immunoglobulin productionGO:0002639280.076
osteoclast differentiationGO:0030316620.076
positive regulation of leukocyte mediated cytotoxicityGO:0001912310.076
regulation of defense response to bacteriumGO:190042430.075
positive regulation of b cell differentiationGO:0045579130.075
positive regulation of transforming growth factor beta1 productionGO:003291420.075
response to organic cyclic compoundGO:00140701980.073
negative regulation of histone deacetylationGO:003106420.073
regulation of b cell proliferationGO:0030888390.073
negative regulation of mapk cascadeGO:0043409650.073
antimicrobial peptide productionGO:000277520.072
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.072
positive regulation of interleukin 10 productionGO:0032733120.072
response to radiationGO:00093141650.071
response to organonitrogen compoundGO:00102432460.070
regulation of ion homeostasisGO:2000021640.070
regulation of tumor necrosis factor biosynthetic processGO:0042534100.069
immunoglobulin secretionGO:0048305170.069
leukocyte activation involved in immune responseGO:00023661260.069
nk t cell differentiationGO:000186580.069
positive regulation of mapk cascadeGO:00434101700.068
negative regulation of myeloid dendritic cell activationGO:003088630.068
telomere maintenanceGO:0000723190.068
granulocyte activationGO:0036230100.067
positive regulation of b cell activationGO:0050871490.067
leukocyte proliferationGO:00706611720.067
cellular response to organonitrogen compoundGO:00714171450.066
regulation of reactive oxygen species metabolic processGO:2000377400.066
cation homeostasisGO:00550802120.065
type ii hypersensitivityGO:000244540.065
innate immune response activating signal transductionGO:0002758500.064
positive regulation of regulated secretory pathwayGO:1903307100.064
negative regulation of b cell activationGO:0050869270.063
neutrophil differentiationGO:003022330.062
response to insulinGO:00328681000.062
response to steroid hormoneGO:0048545560.062
regulation of secretionGO:00510462740.062
negative regulation of mast cell activationGO:003300460.062
negative regulation of toll like receptor 4 signaling pathwayGO:003414430.061
endoderm formationGO:0001706200.061
negative regulation of protein serine threonine kinase activityGO:0071901490.060
cytokine biosynthetic processGO:0042089680.060
negative regulation of creb transcription factor activityGO:003279220.060
regulation of t helper 1 type immune responseGO:0002825170.060
nik nf kappab signalingGO:0038061140.059
regulation of tyrosine phosphorylation of stat3 proteinGO:0042516100.059
regulation of body fluid levelsGO:00508781620.059
regulation of type ii hypersensitivityGO:000289240.059
regulation of cysteine type endopeptidase activityGO:2000116650.058
regulation of leukocyte apoptotic processGO:2000106560.058
cellular response to peptide hormone stimulusGO:0071375920.058
regulation of protein maturationGO:1903317960.057
spinal cord developmentGO:0021510810.055
response to ionizing radiationGO:0010212420.055
cytokine productionGO:00018163190.055
positive regulation of interleukin 1 secretionGO:0050716140.054
nitrogen compound transportGO:00717052710.054
regulation of leukocyte mediated cytotoxicityGO:0001910380.054
cellular calcium ion homeostasisGO:00068741190.053
negative regulation of lymphocyte proliferationGO:0050672450.053
cellular zinc ion homeostasisGO:000688290.053
stem cell fate determinationGO:004886720.053
regulation of translational initiationGO:0006446150.053
t cell homeostatic proliferationGO:000177740.053
positive regulation of humoral immune response mediated by circulating immunoglobulinGO:000292560.053
positive regulation of cytokine production involved in immune responseGO:0002720190.053
negative regulation of lymphocyte activationGO:0051250910.053
positive regulation of tyrosine phosphorylation of stat5 proteinGO:004252360.053
regulation of leukocyte proliferationGO:00706631210.053
erk1 and erk2 cascadeGO:0070371770.052
positive regulation of innate immune responseGO:0045089800.052
regulation of sequence specific dna binding transcription factor activityGO:00510901060.052
stem cell developmentGO:00488642190.052
neutrophil apoptotic processGO:000178130.051
regulation of protein transportGO:00512231630.051
coagulationGO:0050817780.051
regulation of hypersensitivityGO:0002883100.051
protein processingGO:00164851630.050
regulation of protein serine threonine kinase activityGO:00719001570.050
positive regulation of tolerance induction dependent upon immune responseGO:000265410.050
peptidyl tyrosine modificationGO:00182121450.050
actin cytoskeleton organizationGO:00300362200.050
olfactory learningGO:000835520.049
stem cell differentiationGO:00488632680.049
regulation of endopeptidase activityGO:0052548890.049
myeloid cell differentiationGO:00300992330.049
protein maturationGO:00516041760.048
negative regulation of mast cell apoptotic processGO:003302640.047
cytosolic calcium ion homeostasisGO:0051480700.047
negative regulation of growthGO:0045926990.047
regulation of cell killingGO:0031341400.047
natural killer cell differentiationGO:0001779210.047
transmission of nerve impulseGO:0019226760.047
negative regulation of t cell activationGO:0050868650.046
canonical wnt signaling pathwayGO:00600701300.046
fibroblast migrationGO:0010761210.046
regulation of cytokine biosynthetic processGO:0042035590.046
t cell anergyGO:000287040.046
skeletal system developmentGO:00015013560.046
myeloid cell activation involved in immune responseGO:0002275340.046
cell adhesionGO:00071553290.046
tyrosine phosphorylation of stat1 proteinGO:004250830.045
response to peptide hormoneGO:00434341270.045
cell type specific apoptotic processGO:00972852680.045
jak stat cascadeGO:0007259420.045
embryonic epithelial tube formationGO:00018381300.045
macromolecule catabolic processGO:00090572810.045
insulin receptor signaling pathwayGO:0008286490.044
positive regulation of peptidase activityGO:0010952490.044
nuclear transportGO:00511691390.044
positive regulation of cytosolic calcium ion concentrationGO:0007204650.044
regulation of homeostatic processGO:00328441820.043
regulation of lipase activityGO:0060191150.043
positive regulation of cytokine biosynthetic processGO:0042108400.042
t helper cell differentiationGO:0042093280.042
negative t cell selectionGO:0043383130.042
neuroblast differentiationGO:001401620.042
negative regulation of interferon gamma productionGO:0032689180.041
positive regulation of intracellular transportGO:0032388700.041
chromatin organizationGO:00063252060.041
positive regulation of interferon gamma productionGO:0032729390.041
positive regulation of nervous system developmentGO:00519622210.041
ripoptosome assembly involved in necroptotic processGO:190102660.041
regulation of homotypic cell cell adhesionGO:0034110130.041
regulation of bindingGO:00510981110.041
signal transduction in absence of ligandGO:0038034550.040
response to molecule of bacterial originGO:00022371430.040
regulation of interleukin 2 productionGO:0032663280.040
regulation of podosome assemblyGO:007180130.040
negative regulation of endopeptidase activityGO:0010951440.040
regulation of protein kinase activityGO:00458592320.039
stem cell maintenanceGO:00198271300.039
regulation of peripheral t cell tolerance inductionGO:000284910.039
t cell mediated immunityGO:0002456500.039
tolerance induction to self antigenGO:000251340.038
negative regulation of inflammatory responseGO:0050728610.038
regulation of striated muscle cell differentiationGO:0051153810.037
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.037
antigen processing and presentation of peptide antigen via mhc class iiGO:0002495170.037
b cell receptor signaling pathwayGO:0050853200.037
homeostasis of number of cellsGO:00488722100.037
myeloid dendritic cell activationGO:0001773250.036
activation of janus kinase activityGO:004297620.036
transition metal ion homeostasisGO:0055076540.036
negative regulation of phosphate metabolic processGO:00459361840.036
positive regulation of type i hypersensitivityGO:000181230.035
regulation of gamma delta t cell activationGO:004664390.035
positive regulation of myeloid leukocyte cytokine production involved in immune responseGO:006108190.035
regulation of secretion by cellGO:19035302490.035
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:200126930.035
non recombinational repairGO:0000726100.035
neutrophil chemotaxisGO:0030593360.035
negative regulation of response to cytokine stimulusGO:006076190.034
negative regulation of protein catabolic processGO:0042177360.034
hypersensitivityGO:0002524100.034
transformed cell apoptotic processGO:000692730.033
positive regulation of protein modification processGO:00314012990.033
immune response inhibiting cell surface receptor signaling pathwayGO:000276730.032
blood coagulationGO:0007596760.032
regulation of transferase activityGO:00513382630.032

Tcra disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
severe combined immunodeficiencyDOID:62700.310
disease of anatomical entityDOID:700.310
combined t cell and b cell immunodeficiencyDOID:62800.310
immune system diseaseDOID:291400.310
primary immunodeficiency diseaseDOID:61200.310
organ system cancerDOID:005068600.095
disease of cellular proliferationDOID:1456600.095
cancerDOID:16200.095
sensory system diseaseDOID:005015500.045
retinal diseaseDOID:567900.045
nervous system diseaseDOID:86300.045
eye and adnexa diseaseDOID:149200.045
eye diseaseDOID:561400.045
musculoskeletal system diseaseDOID:1700.035