| cytoplasmic transport | GO:0016482 | 234 | 0.178 | Yeast Worm |
| membrane organization | GO:0061024 | 245 | 0.170 | Human |
| regulation of protein localization | GO:0032880 | 231 | 0.087 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.087 | |
| skeletal system development | GO:0001501 | 356 | 0.085 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.082 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.078 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.075 | Human |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.074 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.065 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.062 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 183 | 0.062 | |
| localization within membrane | GO:0051668 | 4 | 0.061 | |
| amine metabolic process | GO:0009308 | 45 | 0.061 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.059 | Human |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.057 | |
| intracellular protein transport | GO:0006886 | 204 | 0.055 | Human |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.055 | Human |
| regulation of secretion | GO:0051046 | 274 | 0.055 | |
| positive regulation of secretion by cell | GO:1903532 | 114 | 0.054 | |
| cation homeostasis | GO:0055080 | 212 | 0.051 | |
| endomembrane system organization | GO:0010256 | 147 | 0.050 | Human |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.050 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.047 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.045 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.045 | |
| cellular homeostasis | GO:0019725 | 240 | 0.045 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.044 | |
| er nucleus signaling pathway | GO:0006984 | 27 | 0.044 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.042 | |
| intra golgi vesicle mediated transport | GO:0006891 | 1 | 0.042 | |
| establishment of vesicle localization | GO:0051650 | 81 | 0.040 | |
| multi multicellular organism process | GO:0044706 | 109 | 0.040 | |
| organelle localization | GO:0051640 | 179 | 0.040 | |
| response to topologically incorrect protein | GO:0035966 | 25 | 0.038 | |
| macromolecule glycosylation | GO:0043413 | 55 | 0.037 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.037 | Human |
| response to organonitrogen compound | GO:0010243 | 246 | 0.037 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.037 | Human |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.036 | |
| oxidation reduction process | GO:0055114 | 342 | 0.036 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.035 | |
| glycoprotein biosynthetic process | GO:0009101 | 89 | 0.035 | |
| endocytosis | GO:0006897 | 168 | 0.035 | |
| regulation of protein exit from endoplasmic reticulum | GO:0070861 | 1 | 0.035 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.035 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.034 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.034 | |
| response to unfolded protein | GO:0006986 | 21 | 0.034 | |
| male gamete generation | GO:0048232 | 285 | 0.034 | |
| positive regulation of growth | GO:0045927 | 104 | 0.033 | |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.033 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.033 | Human |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.033 | |
| regionalization | GO:0003002 | 337 | 0.033 | |
| lymphocyte differentiation | GO:0030098 | 242 | 0.032 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.032 | Human |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.030 | |
| regulation of cell activation | GO:0050865 | 289 | 0.030 | |
| gland development | GO:0048732 | 330 | 0.030 | |
| cellular response to antibiotic | GO:0071236 | 4 | 0.030 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.029 | Human |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.029 | |
| male sex differentiation | GO:0046661 | 109 | 0.029 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.029 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.029 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.029 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.029 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.029 | |
| glycoprotein metabolic process | GO:0009100 | 116 | 0.028 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 126 | 0.028 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.028 | Human |
| regulation of cell migration | GO:0030334 | 219 | 0.027 | |
| regulation of vesicle mediated transport | GO:0060627 | 139 | 0.027 | |
| camera type eye development | GO:0043010 | 266 | 0.026 | |
| circulatory system process | GO:0003013 | 197 | 0.026 | |
| immune effector process | GO:0002252 | 321 | 0.025 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.025 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.025 | |
| regulation of lymphocyte differentiation | GO:0045619 | 107 | 0.024 | |
| digestive tract development | GO:0048565 | 190 | 0.024 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.024 | |
| placenta development | GO:0001890 | 140 | 0.024 | |
| spermatogenesis | GO:0007283 | 284 | 0.023 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.023 | |
| cell adhesion | GO:0007155 | 329 | 0.023 | |
| forebrain development | GO:0030900 | 302 | 0.023 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.023 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.023 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.023 | Human |
| amide transport | GO:0042886 | 138 | 0.023 | |
| 4 hydroxyproline metabolic process | GO:0019471 | 5 | 0.023 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.023 | Human |
| cellular response to biotic stimulus | GO:0071216 | 92 | 0.022 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.022 | Human |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.022 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.022 | Human |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.022 | |
| transmembrane transport | GO:0055085 | 412 | 0.022 | |
| regulation of protein transport | GO:0051223 | 163 | 0.022 | |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.022 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.022 | Human |
| nucleotide metabolic process | GO:0009117 | 332 | 0.021 | Human |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.021 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.021 | |
| cation transport | GO:0006812 | 399 | 0.021 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.021 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.021 | |
| response to growth factor | GO:0070848 | 198 | 0.021 | |
| t cell activation | GO:0042110 | 289 | 0.020 | |
| lateral inhibition | GO:0046331 | 1 | 0.020 | |
| protein targeting | GO:0006605 | 143 | 0.020 | Human |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 77 | 0.020 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.020 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.020 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.020 | Human |
| regulation of cell motility | GO:2000145 | 236 | 0.020 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.020 | |
| synaptic transmission | GO:0007268 | 329 | 0.020 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.020 | |
| ribonucleotide biosynthetic process | GO:0009260 | 59 | 0.019 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.019 | |
| inter male aggressive behavior | GO:0002121 | 3 | 0.019 | |
| cellular response to lipid | GO:0071396 | 145 | 0.019 | |
| chromatin organization | GO:0006325 | 206 | 0.019 | |
| maintenance of location | GO:0051235 | 89 | 0.019 | Yeast |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.019 | |
| positive regulation of secretion | GO:0051047 | 130 | 0.019 | |
| bone development | GO:0060348 | 120 | 0.019 | |
| multicellular organismal signaling | GO:0035637 | 91 | 0.019 | |
| lymphocyte mediated immunity | GO:0002449 | 139 | 0.018 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.018 | Human |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.018 | |
| regulation of er to golgi vesicle mediated transport | GO:0060628 | 4 | 0.018 | |
| skeletal system morphogenesis | GO:0048705 | 203 | 0.018 | |
| calcium ion homeostasis | GO:0055074 | 127 | 0.018 | |
| protein exit from endoplasmic reticulum | GO:0032527 | 1 | 0.018 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.018 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.018 | |
| hormone secretion | GO:0046879 | 128 | 0.018 | |
| positive regulation of cell motility | GO:2000147 | 116 | 0.018 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.017 | |
| development of primary male sexual characteristics | GO:0046546 | 88 | 0.017 | |
| t cell differentiation | GO:0030217 | 174 | 0.017 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.017 | |
| golgi vesicle transport | GO:0048193 | 30 | 0.017 | Yeast Worm |
| asymmetric stem cell division | GO:0098722 | 3 | 0.017 | |
| positive regulation of phospholipase activity | GO:0010518 | 3 | 0.017 | |
| muscle tissue development | GO:0060537 | 308 | 0.017 | |
| organophosphate biosynthetic process | GO:0090407 | 122 | 0.017 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.017 | Human |
| regulation of actin filament based process | GO:0032970 | 99 | 0.017 | |
| histone modification | GO:0016570 | 159 | 0.017 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.017 | |
| spermatid development | GO:0007286 | 108 | 0.017 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.017 | |
| cartilage development | GO:0051216 | 140 | 0.016 | |
| negative regulation of cell activation | GO:0050866 | 111 | 0.016 | |
| regulation of t cell differentiation | GO:0045580 | 83 | 0.016 | |
| connective tissue development | GO:0061448 | 179 | 0.016 | |
| regulation of vacuole organization | GO:0044088 | 4 | 0.016 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.016 | Human |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.016 | |
| response to oxygen radical | GO:0000305 | 16 | 0.016 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.016 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.016 | Human |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.016 | Human |
| endoplasmic reticulum unfolded protein response | GO:0030968 | 19 | 0.016 | |
| nucleoside phosphate biosynthetic process | GO:1901293 | 79 | 0.016 | |
| substantia nigra development | GO:0021762 | 2 | 0.016 | |
| male gonad development | GO:0008584 | 88 | 0.016 | |
| regulation of multi organism process | GO:0043900 | 111 | 0.016 | |
| multicellular organism growth | GO:0035264 | 161 | 0.016 | |
| actin polymerization or depolymerization | GO:0008154 | 54 | 0.016 | |
| compound eye development | GO:0048749 | 1 | 0.016 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.016 | Human |
| macromolecule catabolic process | GO:0009057 | 281 | 0.015 | |
| multi organism reproductive behavior | GO:0044705 | 29 | 0.015 | |
| extracellular structure organization | GO:0043062 | 148 | 0.015 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.015 | Human |
| regulation of protein complex assembly | GO:0043254 | 83 | 0.015 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.015 | |
| cytokine production | GO:0001816 | 319 | 0.015 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.015 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.015 | |
| protein maturation | GO:0051604 | 176 | 0.015 | |
| methylation | GO:0032259 | 134 | 0.015 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.015 | |
| sensory perception | GO:0007600 | 245 | 0.015 | |
| action potential | GO:0001508 | 78 | 0.015 | |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.015 | |
| cellular response to external stimulus | GO:0071496 | 88 | 0.015 | |
| establishment of protein localization to membrane | GO:0090150 | 54 | 0.015 | Human |
| purine containing compound biosynthetic process | GO:0072522 | 70 | 0.015 | |
| epithelial cell development | GO:0002064 | 159 | 0.015 | |
| vacuole organization | GO:0007033 | 38 | 0.015 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.015 | Human |
| striated muscle tissue development | GO:0014706 | 293 | 0.014 | |
| monocarboxylic acid metabolic process | GO:0032787 | 191 | 0.014 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.014 | |
| peptide hormone secretion | GO:0030072 | 109 | 0.014 | |
| nucleotide biosynthetic process | GO:0009165 | 78 | 0.014 | |
| multi organism behavior | GO:0051705 | 62 | 0.014 | |
| b cell activation | GO:0042113 | 161 | 0.014 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.014 | |
| lung development | GO:0030324 | 164 | 0.014 | |
| protein folding | GO:0006457 | 28 | 0.014 | |
| cellular response to lipopolysaccharide | GO:0071222 | 77 | 0.014 | |
| regulation of epithelial cell proliferation | GO:0050678 | 141 | 0.014 | |
| protein localization to membrane | GO:0072657 | 108 | 0.014 | Human |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.014 | |
| glucose metabolic process | GO:0006006 | 92 | 0.014 | |
| digestive system development | GO:0055123 | 200 | 0.014 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.014 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.014 | Human |
| myeloid leukocyte differentiation | GO:0002573 | 119 | 0.014 | |
| cellular metal ion homeostasis | GO:0006875 | 151 | 0.014 | |
| extracellular matrix organization | GO:0030198 | 147 | 0.014 | |
| anatomical structure homeostasis | GO:0060249 | 145 | 0.014 | |
| regulation of protein stability | GO:0031647 | 52 | 0.013 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.013 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.013 | |
| regulation of response to wounding | GO:1903034 | 189 | 0.013 | |
| mapk cascade | GO:0000165 | 281 | 0.013 | |
| receptor mediated endocytosis | GO:0006898 | 51 | 0.013 | |
| protein acylation | GO:0043543 | 64 | 0.013 | |
| golgi organization | GO:0007030 | 9 | 0.013 | Human |
| chromatin modification | GO:0016568 | 187 | 0.013 | |
| spermatid differentiation | GO:0048515 | 115 | 0.013 | |
| peptide transport | GO:0015833 | 133 | 0.013 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.013 | Human |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.013 | |
| mitotic cytokinesis | GO:0000281 | 4 | 0.013 | |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.013 | |
| regulation of reproductive process | GO:2000241 | 66 | 0.013 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.013 | |
| cell aging | GO:0007569 | 35 | 0.013 | |
| hexose metabolic process | GO:0019318 | 98 | 0.013 | |
| positive regulation of protein transport | GO:0051222 | 93 | 0.013 | |
| single organism cell adhesion | GO:0098602 | 156 | 0.013 | |
| blood circulation | GO:0008015 | 195 | 0.013 | |
| negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090101 | 61 | 0.013 | |
| regulation of endocytosis | GO:0030100 | 69 | 0.013 | |
| innate immune response | GO:0045087 | 157 | 0.013 | |
| divalent inorganic cation homeostasis | GO:0072507 | 138 | 0.013 | |
| multicellular organismal homeostasis | GO:0048871 | 164 | 0.012 | |
| inflammatory response | GO:0006954 | 244 | 0.012 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.012 | |
| metencephalon development | GO:0022037 | 89 | 0.012 | |
| vesicle localization | GO:0051648 | 86 | 0.012 | |
| organic hydroxy compound metabolic process | GO:1901615 | 203 | 0.012 | |
| dephosphorylation | GO:0016311 | 129 | 0.012 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.012 | Human |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.012 | Human |
| protein secretion | GO:0009306 | 111 | 0.012 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.012 | |
| glucose homeostasis | GO:0042593 | 128 | 0.012 | |
| respiratory system development | GO:0060541 | 190 | 0.012 | |
| regulation of lamellipodium assembly | GO:0010591 | 3 | 0.012 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.012 | |
| chromosome segregation | GO:0007059 | 48 | 0.012 | |
| gtp catabolic process | GO:0006184 | 143 | 0.012 | Human |
| positive regulation of endocytosis | GO:0045807 | 42 | 0.012 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.012 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 159 | 0.012 | |
| developmental maturation | GO:0021700 | 193 | 0.012 | |
| cellular response to extracellular stimulus | GO:0031668 | 81 | 0.012 | |
| leukocyte mediated immunity | GO:0002443 | 174 | 0.012 | |
| peptide secretion | GO:0002790 | 114 | 0.011 | |
| regulation of hormone secretion | GO:0046883 | 88 | 0.011 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.011 | Human |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.011 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.011 | Human |
| cellular response to nutrient levels | GO:0031669 | 64 | 0.011 | |
| limb development | GO:0060173 | 166 | 0.011 | |
| post mating behavior | GO:0045297 | 3 | 0.011 | |
| membrane lipid metabolic process | GO:0006643 | 53 | 0.011 | |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.011 | |
| response to inorganic substance | GO:0010035 | 96 | 0.011 | |
| regulation of peptide hormone secretion | GO:0090276 | 75 | 0.011 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.011 | |
| midgut development | GO:0007494 | 4 | 0.011 | |
| positive regulation of peptide hormone secretion | GO:0090277 | 31 | 0.011 | |
| ossification | GO:0001503 | 216 | 0.011 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.011 | Human |
| peptidyl lysine modification | GO:0018205 | 77 | 0.011 | |
| rna processing | GO:0006396 | 105 | 0.011 | |
| embryonic organ morphogenesis | GO:0048562 | 276 | 0.011 | |
| neuron death | GO:0070997 | 154 | 0.011 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.011 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.011 | Human |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.011 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 122 | 0.011 | Human |
| monosaccharide metabolic process | GO:0005996 | 106 | 0.010 | |
| regulation of actin cytoskeleton organization | GO:0032956 | 84 | 0.010 | |
| cellular response to topologically incorrect protein | GO:0035967 | 25 | 0.010 | |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.010 | Human |
| tissue homeostasis | GO:0001894 | 115 | 0.010 | |
| gtp metabolic process | GO:0046039 | 144 | 0.010 | Human |
| positive regulation of organelle organization | GO:0010638 | 128 | 0.010 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.010 | |
| maintenance of location in cell | GO:0051651 | 24 | 0.010 | Yeast |
| peptidyl asparagine modification | GO:0018196 | 1 | 0.010 | |
| exocytosis | GO:0006887 | 121 | 0.010 | |
| glial cell differentiation | GO:0010001 | 131 | 0.010 | |
| sphingolipid metabolic process | GO:0006665 | 45 | 0.010 | |
| protein glycosylation | GO:0006486 | 55 | 0.010 | |
| copii coated vesicle budding | GO:0090114 | 2 | 0.010 | |