IMP: Integrative Multi-species Prediction

Mus musculus

0 known processes

Tmprss4

transmembrane protease, serine 4

(Aliases: mCAP2,MGC29209)

Entrez: 214523
Ensembl: ENSMUSG00000032091
UniProtKB: Q8VCA5

Process Predictions
Disease Predictions

Tmprss4 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
cation transport	GO:0006812	399	0.285	Mouse
inorganic ion transmembrane transport	GO:0098660	234	0.199	Mouse
nucleotide metabolic process	GO:0009117	332	0.077
cellular amino acid metabolic process	GO:0006520	103	0.076	Mouse
anion transport	GO:0006820	177	0.074
skin development	GO:0043588	220	0.069
regulation of membrane potential	GO:0042391	192	0.068
inorganic cation transmembrane transport	GO:0098662	207	0.065	Mouse
cellular amine metabolic process	GO:0044106	44	0.062	Mouse
purine nucleoside triphosphate metabolic process	GO:0009144	226	0.062
epidermis development	GO:0008544	187	0.059
heterocycle catabolic process	GO:0046700	280	0.055
ribonucleotide catabolic process	GO:0009261	208	0.055
nucleoside phosphate metabolic process	GO:0006753	338	0.055
ion transmembrane transport	GO:0034220	361	0.052	Mouse
purine containing compound metabolic process	GO:0072521	311	0.050
peptide transport	GO:0015833	133	0.050
regulation of hormone levels	GO:0010817	211	0.049	Mouse
regulation of cellular catabolic process	GO:0031329	242	0.048
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.048	Mouse
nucleoside catabolic process	GO:0009164	206	0.046
purine containing compound catabolic process	GO:0072523	213	0.044
organic cyclic compound catabolic process	GO:1901361	295	0.044
purine ribonucleoside metabolic process	GO:0046128	241	0.044
nucleobase containing small molecule metabolic process	GO:0055086	352	0.043
purine nucleoside metabolic process	GO:0042278	241	0.043
transmembrane transport	GO:0055085	412	0.040	Mouse
regulation of protein serine threonine kinase activity	GO:0071900	157	0.040
purine ribonucleoside triphosphate metabolic process	GO:0009205	220	0.039
negative regulation of molecular function	GO:0044092	258	0.039	Mouse
multicellular organismal signaling	GO:0035637	91	0.039
cation transmembrane transport	GO:0098655	266	0.039	Mouse
regulation of secretion	GO:0051046	274	0.038	Mouse
carbohydrate derivative biosynthetic process	GO:1901137	183	0.038
ribonucleoside metabolic process	GO:0009119	245	0.038
amine metabolic process	GO:0009308	45	0.037	Mouse
glycosyl compound catabolic process	GO:1901658	206	0.036
purine ribonucleoside triphosphate catabolic process	GO:0009207	199	0.036
regulation of cellular amino acid metabolic process	GO:0006521	5	0.035	Mouse
detection of stimulus involved in sensory perception	GO:0050906	44	0.035	Mouse
posttranscriptional regulation of gene expression	GO:0010608	155	0.035
regulation of body fluid levels	GO:0050878	162	0.035
cellular nitrogen compound catabolic process	GO:0044270	280	0.035
purine nucleotide metabolic process	GO:0006163	302	0.034
cellular homeostasis	GO:0019725	240	0.034
protein modification by small protein conjugation or removal	GO:0070647	207	0.034
ribose phosphate metabolic process	GO:0019693	291	0.033
cellular ketone metabolic process	GO:0042180	84	0.033	Mouse
ras protein signal transduction	GO:0007265	77	0.033
nucleotide catabolic process	GO:0009166	217	0.033
hormone secretion	GO:0046879	128	0.033
nucleoside phosphate catabolic process	GO:1901292	222	0.032
detection of chemical stimulus involved in sensory perception of taste	GO:0050912	3	0.032
divalent inorganic cation transport	GO:0072511	178	0.032
purine nucleoside catabolic process	GO:0006152	205	0.031
positive regulation of cellular amine metabolic process	GO:0033240	5	0.031	Mouse
regulation of defense response	GO:0031347	233	0.031
nucleoside metabolic process	GO:0009116	246	0.031
glycosyl compound metabolic process	GO:1901657	246	0.030
ribonucleoside catabolic process	GO:0042454	206	0.030
purine ribonucleoside catabolic process	GO:0046130	205	0.030
nitrogen compound transport	GO:0071705	271	0.030
purine ribonucleotide catabolic process	GO:0009154	208	0.030
ribonucleotide metabolic process	GO:0009259	291	0.030
regulation of hydrolase activity	GO:0051336	246	0.030	Mouse
cell type specific apoptotic process	GO:0097285	268	0.029
organophosphate catabolic process	GO:0046434	232	0.029
multicellular organismal homeostasis	GO:0048871	164	0.028
pyrimidine containing compound transmembrane transport	GO:0072531	5	0.028
intracellular mrna localization	GO:0008298	4	0.028
sensory perception	GO:0007600	245	0.028	Mouse
aromatic compound catabolic process	GO:0019439	286	0.027
ribonucleoside triphosphate catabolic process	GO:0009203	199	0.027
vitamin transmembrane transport	GO:0035461	4	0.027
action potential	GO:0001508	78	0.027
t cell activation	GO:0042110	289	0.027
keratinocyte differentiation	GO:0030216	48	0.027
immune response regulating signaling pathway	GO:0002764	125	0.027
organonitrogen compound catabolic process	GO:1901565	264	0.026
purine nucleoside triphosphate catabolic process	GO:0009146	203	0.026
cellular response to organonitrogen compound	GO:0071417	145	0.026
compound eye development	GO:0048749	1	0.026
response to organonitrogen compound	GO:0010243	246	0.026
regulation of homeostatic process	GO:0032844	182	0.025	Mouse
purine ribonucleotide metabolic process	GO:0009150	290	0.025
sodium ion transport	GO:0006814	73	0.025
epithelial cell development	GO:0002064	159	0.025
inorganic anion transport	GO:0015698	43	0.025
immune effector process	GO:0002252	321	0.025
nucleoside triphosphate metabolic process	GO:0009141	230	0.024
actin cytoskeleton organization	GO:0030036	220	0.024
amide transport	GO:0042886	138	0.024
regulation of nucleotide catabolic process	GO:0030811	122	0.023
purine nucleotide catabolic process	GO:0006195	211	0.023
regulation of cell migration	GO:0030334	219	0.023
divalent inorganic cation homeostasis	GO:0072507	138	0.023
protein processing	GO:0016485	163	0.023	Mouse
innate immune response	GO:0045087	157	0.023
negative regulation of synapse assembly	GO:0051964	3	0.023
regulation of purine nucleotide metabolic process	GO:1900542	169	0.022
gtp metabolic process	GO:0046039	144	0.022
peptide secretion	GO:0002790	114	0.022
positive regulation of defense response	GO:0031349	124	0.021
regulation of nucleotide metabolic process	GO:0006140	169	0.021
mapk cascade	GO:0000165	281	0.021
nucleoside triphosphate catabolic process	GO:0009143	205	0.021
negative regulation of hydrolase activity	GO:0051346	71	0.021	Mouse
cation homeostasis	GO:0055080	212	0.021	Mouse
regulation of secretion by cell	GO:1903530	249	0.021
potassium ion transport	GO:0006813	52	0.021	Mouse
cytokinetic process	GO:0032506	2	0.021
regulation of protein kinase activity	GO:0045859	232	0.020
germ cell development	GO:0007281	185	0.020
developmental maturation	GO:0021700	193	0.020
respiratory system development	GO:0060541	190	0.020
lipid biosynthetic process	GO:0008610	179	0.020
regulation of mapk cascade	GO:0043408	248	0.020
regulation of protein transport	GO:0051223	163	0.020
insulin secretion	GO:0030073	89	0.020
metal ion homeostasis	GO:0055065	189	0.020	Mouse
negative regulation of multi organism process	GO:0043901	68	0.020
ribonucleoside triphosphate metabolic process	GO:0009199	220	0.020
regulation of purine nucleotide catabolic process	GO:0033121	122	0.019
immune response activating signal transduction	GO:0002757	116	0.019
neuronal action potential	GO:0019228	54	0.019
response to drug	GO:0042493	75	0.019
regulation of cellular amine metabolic process	GO:0033238	20	0.019	Mouse
rho protein signal transduction	GO:0007266	32	0.019
cell adhesion	GO:0007155	329	0.019
small gtpase mediated signal transduction	GO:0007264	97	0.019
organonitrogen compound biosynthetic process	GO:1901566	192	0.019
locomotory behavior	GO:0007626	195	0.019
potassium ion transmembrane transport	GO:0071805	43	0.019	Mouse
regulation of cell activation	GO:0050865	289	0.018
renal sodium excretion	GO:0035812	3	0.018	Mouse
transmission of nerve impulse	GO:0019226	76	0.018
response to lipopolysaccharide	GO:0032496	128	0.018
positive regulation of protein modification process	GO:0031401	299	0.018
regulation of t cell activation	GO:0050863	170	0.018
carbohydrate derivative catabolic process	GO:1901136	231	0.018
leukocyte differentiation	GO:0002521	342	0.018
protein maturation	GO:0051604	176	0.018	Mouse
protein ubiquitination	GO:0016567	171	0.018
regulation of cellular ketone metabolic process	GO:0010565	66	0.018	Mouse
regulation of gtp catabolic process	GO:0033124	113	0.018
bone remodeling	GO:0046849	53	0.018
regulation of reactive oxygen species metabolic process	GO:2000377	40	0.018
negative regulation of cellular protein metabolic process	GO:0032269	247	0.018
regulation of cytokine production	GO:0001817	266	0.018
defense response to bacterium	GO:0042742	119	0.017
guanosine containing compound catabolic process	GO:1901069	144	0.017
regulation of map kinase activity	GO:0043405	120	0.017
gtp catabolic process	GO:0006184	143	0.017
calcium ion homeostasis	GO:0055074	127	0.016
negative regulation of hormone biosynthetic process	GO:0032353	4	0.016
cellular macromolecule catabolic process	GO:0044265	206	0.016
exocytosis	GO:0006887	121	0.016
defense response to other organism	GO:0098542	197	0.016
defecation	GO:0030421	1	0.016
glycerolipid metabolic process	GO:0046486	122	0.016
regulation of ras gtpase activity	GO:0032318	88	0.016
actin filament bundle assembly	GO:0051017	40	0.016
endomembrane system organization	GO:0010256	147	0.016
nk t cell proliferation	GO:0001866	2	0.016
coagulation	GO:0050817	78	0.016
positive regulation of mapk cascade	GO:0043410	170	0.016
regulation of cell motility	GO:2000145	236	0.016
regulation of defense response to bacterium	GO:1900424	3	0.016
maintenance of location	GO:0051235	89	0.015
regulation of rho protein signal transduction	GO:0035023	71	0.015
detection of stimulus	GO:0051606	84	0.015	Mouse
positive regulation of programmed cell death	GO:0043068	218	0.015
prevention of polyspermy	GO:0060468	4	0.015
dephosphorylation	GO:0016311	129	0.015	Mouse
hypotonic response	GO:0006971	3	0.015
protein modification by small protein conjugation	GO:0032446	187	0.015
alpha beta t cell activation	GO:0046631	91	0.015
regulation of cell cycle	GO:0051726	281	0.015
inflammatory response	GO:0006954	244	0.015
lymphocyte apoptotic process	GO:0070227	54	0.015
regulation of protein localization	GO:0032880	231	0.015
cellular chemical homeostasis	GO:0055082	215	0.015
positive regulation of protein kinase activity	GO:0045860	144	0.014
cellular metal ion homeostasis	GO:0006875	151	0.014
guanosine containing compound metabolic process	GO:1901068	144	0.014
sodium ion export	GO:0071436	2	0.014
negative regulation of cell proliferation	GO:0008285	296	0.014
syncytium formation by plasma membrane fusion	GO:0000768	42	0.014
anatomical structure maturation	GO:0071695	49	0.014
regulation of rho gtpase activity	GO:0032319	58	0.014
protein localization to membrane	GO:0072657	108	0.014
positive regulation of response to wounding	GO:1903036	66	0.014
regulation of multi organism process	GO:0043900	111	0.014
positive regulation of apoptotic process	GO:0043065	217	0.014
positive regulation of nucleotide catabolic process	GO:0030813	88	0.014
natural killer cell proliferation	GO:0001787	3	0.014
cellular response to organic cyclic compound	GO:0071407	87	0.014
reactive oxygen species metabolic process	GO:0072593	84	0.014
lymphocyte activation involved in immune response	GO:0002285	93	0.014
negative regulation of secretion	GO:0051048	61	0.014
sodium ion export from cell	GO:0036376	1	0.014
anatomical structure homeostasis	GO:0060249	145	0.014
regulation of cellular response to stress	GO:0080135	159	0.014
membrane organization	GO:0061024	245	0.013
leukocyte chemotaxis	GO:0030595	69	0.013
regulation of organelle organization	GO:0033043	289	0.013
hematopoietic progenitor cell differentiation	GO:0002244	143	0.013
thiamine transport	GO:0015888	2	0.013
sensory perception of sound	GO:0007605	97	0.013	Mouse
intrinsic apoptotic signaling pathway	GO:0097193	132	0.013
regulation of lymphocyte activation	GO:0051249	240	0.013
organelle fission	GO:0048285	170	0.013
regulation of ras protein signal transduction	GO:0046578	114	0.013
organophosphate biosynthetic process	GO:0090407	122	0.013
carboxylic acid biosynthetic process	GO:0046394	86	0.013
endocytosis	GO:0006897	168	0.013
regulation of nucleoside metabolic process	GO:0009118	130	0.013
muscle cell differentiation	GO:0042692	261	0.013
striated muscle tissue development	GO:0014706	293	0.013
regulation of peptide hormone secretion	GO:0090276	75	0.013
regulation of peptidase activity	GO:0052547	96	0.013
regulation of ion transport	GO:0043269	215	0.013
wound healing	GO:0042060	157	0.013
serotonin secretion by mast cell	GO:0002552	1	0.013
hair follicle development	GO:0001942	85	0.013
cellular potassium ion transport	GO:0071804	43	0.013	Mouse
cellular ion homeostasis	GO:0006873	165	0.013
negative regulation of phosphate metabolic process	GO:0045936	184	0.012	Mouse
circulatory system process	GO:0003013	197	0.012	Mouse
regulation of kinase activity	GO:0043549	249	0.012
regulation of cellular component biogenesis	GO:0044087	181	0.012
activation of immune response	GO:0002253	138	0.012
interleukin 8 production	GO:0032637	4	0.012
regulation of peptide secretion	GO:0002791	77	0.012
negative regulation of endopeptidase activity	GO:0010951	44	0.012
cellular protein catabolic process	GO:0044257	155	0.012
sequestering of calcium ion	GO:0051208	18	0.012
sodium ion transmembrane transport	GO:0035725	49	0.012
positive regulation of transferase activity	GO:0051347	167	0.012
leukocyte migration	GO:0050900	124	0.012
positive regulation of protein catabolic process	GO:0045732	60	0.012
spermatogenesis	GO:0007283	284	0.012
negative regulation of cellular component organization	GO:0051129	194	0.012
mitotic cell cycle	GO:0000278	195	0.012
purine containing compound biosynthetic process	GO:0072522	70	0.012
innate immune response activating signal transduction	GO:0002758	50	0.012
organic acid biosynthetic process	GO:0016053	86	0.012
intracellular protein transport	GO:0006886	204	0.012
cdc42 protein signal transduction	GO:0032488	0	0.012
translation	GO:0006412	93	0.012
cellular lipid metabolic process	GO:0044255	323	0.012
lymphocyte proliferation	GO:0046651	164	0.012
cellularization	GO:0007349	1	0.012
cell matrix adhesion	GO:0007160	68	0.011
regulation of proteolysis	GO:0030162	164	0.011
regulation of transferase activity	GO:0051338	263	0.011
negative regulation of peptidase activity	GO:0010466	46	0.011
cell junction organization	GO:0034330	77	0.011
apoptotic signaling pathway	GO:0097190	306	0.011
glycoprotein metabolic process	GO:0009100	116	0.011
regulation of vesicle mediated transport	GO:0060627	139	0.011
regulation of systemic arterial blood pressure by atrial natriuretic peptide	GO:0003050	2	0.011	Mouse
skeletal system development	GO:0001501	356	0.011
cell substrate adhesion	GO:0031589	130	0.011
regulation of protein maturation	GO:1903317	96	0.011
cell chemotaxis	GO:0060326	81	0.011
lateral inhibition	GO:0046331	1	0.011
blood circulation	GO:0008015	195	0.011	Mouse
positive regulation of muscle cell differentiation	GO:0051149	39	0.011
muscle contraction	GO:0006936	101	0.011
calcium ion transport	GO:0006816	159	0.011
positive regulation of jnk cascade	GO:0046330	46	0.011
regulation of protein catabolic process	GO:0042176	108	0.011
regulation of inflammatory response	GO:0050727	147	0.011
positive regulation of protein phosphorylation	GO:0001934	242	0.011
single organism cell adhesion	GO:0098602	156	0.011
regulation of cell adhesion	GO:0030155	154	0.011
divalent metal ion transport	GO:0070838	172	0.011
positive regulation of stress activated mapk cascade	GO:0032874	48	0.011
synaptic transmission	GO:0007268	329	0.011
regulation of striated muscle cell differentiation	GO:0051153	81	0.011
hair cycle	GO:0042633	90	0.011
regulation of intracellular transport	GO:0032386	159	0.011
positive regulation of sodium ion transmembrane transport	GO:1902307	4	0.011
calcium independent cell cell adhesion via plasma membrane cell adhesion molecules	GO:0016338	4	0.011
regulation of synaptic growth at neuromuscular junction	GO:0008582	4	0.011
cytoplasmic transport	GO:0016482	234	0.011
rac protein signal transduction	GO:0016601	13	0.011
chemotaxis	GO:0006935	247	0.011
positive regulation of protein transport	GO:0051222	93	0.011
positive regulation of eosinophil migration	GO:2000418	2	0.010
peptidyl serine modification	GO:0018209	83	0.010
regulation of establishment of protein localization	GO:0070201	181	0.010
regulation of sodium ion export	GO:1903273	1	0.010
antibacterial peptide biosynthetic process	GO:0002780	2	0.010
cell cell junction organization	GO:0045216	72	0.010
positive regulation of cellular catabolic process	GO:0031331	148	0.010
peptidyl amino acid modification	GO:0018193	336	0.010
microtubule based process	GO:0007017	236	0.010
g protein coupled receptor signaling pathway	GO:0007186	243	0.010

Tmprss4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.014
respiratory system disease	DOID:1579	0.012
disease of anatomical entity	DOID:7	0.012
lower respiratory tract disease	DOID:0050161	0.012
cancer	DOID:162	0.011

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network