Mus musculus

543 known processes

Tnf

tumor necrosis factor

(Aliases: TNFalpha,DIF,Tnfsf1a,Tnfa,TNFSF2,TNF-alpha,MGC151434)

Tnf biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of chronic inflammatory response to antigenic stimulusGO:000287431.000
antibacterial peptide productionGO:000277821.000
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601451.000
osteoclast proliferationGO:000215841.000
Mouse
defense response to other organismGO:00985421971.000
positive regulation of myoblast differentiationGO:004566381.000
Mouse
regulation of fever generationGO:003162061.000
fever generationGO:000166071.000
i kappab kinase nf kappab signalingGO:0007249851.000
chronic inflammatory responseGO:000254491.000
antibacterial humoral responseGO:001973181.000
cellular response to cytokine stimulusGO:00713451891.000
positive regulation of antibacterial peptide biosynthetic processGO:000696311.000
positive regulation of defense responseGO:00313491241.000
regulation of inflammatory response to antigenic stimulusGO:0002861211.000
lymphocyte activation involved in immune responseGO:0002285931.000
Mouse
regulation of growth of symbiont in hostGO:0044126191.000
cellular response to molecule of bacterial originGO:0071219831.000
positive regulation of isotype switching to igg isotypesGO:004830471.000
cytokine production involved in immune responseGO:0002367341.000
regulation of interleukin 6 productionGO:0032675551.000
tumor necrosis factor mediated signaling pathwayGO:0033209131.000
positive regulation of adaptive immune responseGO:0002821611.000
positive regulation of chronic inflammatory responseGO:000267841.000
cellular response to lipopolysaccharideGO:0071222771.000
negative regulation of inflammatory response to antigenic stimulusGO:0002862101.000
positive regulation of interferon gamma productionGO:0032729391.000
regulation of sequence specific dna binding transcription factor activityGO:00510901061.000
Mouse
somatic diversification of immunoglobulins involved in immune responseGO:0002208361.000
Mouse
immunoglobulin production involved in immunoglobulin mediated immune responseGO:0002381431.000
Mouse
interleukin 12 productionGO:0032615321.000
adaptive immune responseGO:00022501551.000
defense response to bacteriumGO:00427421191.000
cellular response to lipidGO:00713961451.000
t helper cell differentiationGO:0042093281.000
programmed necrotic cell deathGO:0097300281.000
response to tumor necrosis factorGO:0034612261.000
modulation of growth of symbiont involved in interaction with hostGO:0044144191.000
regulation of cell activationGO:00508652891.000
Mouse
interleukin 10 secretionGO:007260841.000
leukocyte differentiationGO:00025213421.000
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630571.000
interleukin 5 secretionGO:007260321.000
positive regulation of chronic inflammatory response to antigenic stimulusGO:000287621.000
necroptotic processGO:0070266211.000
production of molecular mediator of immune responseGO:00024401031.000
regulation of cytokine production involved in immune responseGO:0002718261.000
cytokine productionGO:00018163191.000
extrinsic apoptotic signaling pathwayGO:00971911261.000
nucleotide binding oligomerization domain containing signaling pathwayGO:007042361.000
regulation of inflammatory responseGO:00507271471.000
antibacterial peptide biosynthetic processGO:000278021.000
defense response to gram negative bacteriumGO:0050829281.000
Fly
immunoglobulin mediated immune responseGO:0016064691.000
positive regulation of translational initiation by ironGO:004599421.000
regulation of b cell proliferationGO:0030888391.000
positive regulation of fever generationGO:003162261.000
necroptotic signaling pathwayGO:009752731.000
somatic diversification of immune receptorsGO:0002200531.000
Mouse
regulation of acute inflammatory responseGO:0002673270.999
immunoglobulin secretionGO:0048305170.999
humoral immune responseGO:0006959570.999
positive regulation of lymphocyte proliferationGO:0050671700.999
response to lipopolysaccharideGO:00324961280.999
regulation of chronic inflammatory responseGO:000267670.999
positive regulation of inflammatory response to antigenic stimulusGO:0002863110.999
regulation of leukocyte proliferationGO:00706631210.999
cellular response to biotic stimulusGO:0071216920.999
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.999
antimicrobial peptide productionGO:000277520.999
positive regulation of interleukin 12 productionGO:0032735210.999
leukocyte activation involved in immune responseGO:00023661260.999
Mouse
positive regulation of b cell proliferationGO:0030890240.999
regulation of defense response to bacteriumGO:190042430.999
cd4 positive alpha beta t cell differentiationGO:0043367410.999
regulation of response to woundingGO:19030341890.999
cellular response to amino acid stimulusGO:0071230290.999
lymph node developmentGO:0048535180.999
Mouse
regulation of antibacterial peptide biosynthetic processGO:000280810.999
somatic recombination of immunoglobulin genes involved in immune responseGO:0002204360.999
Mouse
lipopolysaccharide mediated signaling pathwayGO:0031663250.999
negative regulation of growth of symbiont in hostGO:0044130190.999
reactive oxygen species metabolic processGO:0072593840.999
positive regulation of lymphocyte activationGO:00512511400.999
Mouse
interleukin 6 productionGO:0032635580.999
regulation of cytokine biosynthetic processGO:0042035590.999
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.999
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.999
regulation of cellular ketone metabolic processGO:0010565660.999
regulation of lymphocyte proliferationGO:00506701170.999
negative regulation of multi organism processGO:0043901680.999
leukocyte mediated immunityGO:00024431740.999
positive regulation of cell deathGO:00109422240.999
regulation of antimicrobial humoral responseGO:000275930.998
negative regulation of interleukin 10 secretionGO:200118020.998
regulation of map kinase activityGO:00434051200.998
Mouse
regulation of antibacterial peptide productionGO:000278610.998
positive regulation of leukocyte mediated immunityGO:0002705700.998
b cell activation involved in immune responseGO:0002312500.998
Mouse
peptidyl tyrosine phosphorylationGO:00181081430.998
somatic diversification of immune receptors via germline recombination within a single locusGO:0002562510.998
Mouse
cellular response to tumor necrosis factorGO:0071356210.998
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.998
regulation of leukocyte mediated immunityGO:00027031040.998
positive regulation of reactive oxygen species biosynthetic processGO:190342820.998
growth of symbiont involved in interaction with hostGO:0044116230.998
chronic inflammatory response to antigenic stimulusGO:000243930.998
cytokine mediated signaling pathwayGO:00192211150.998
icosanoid secretionGO:0032309120.998
Mouse
regulation of fever generation by regulation of prostaglandin secretionGO:007181020.997
Mouse
positive regulation of production of molecular mediator of immune responseGO:0002702450.997
positive regulation of leukocyte proliferationGO:0070665730.997
cd4 positive alpha beta t cell activationGO:0035710450.997
regulation of cd4 positive alpha beta t cell activationGO:2000514240.997
regulation of protein serine threonine kinase activityGO:00719001570.997
Mouse
t cell activationGO:00421102890.997
Mouse
activation of mapk activityGO:0000187590.997
Mouse
positive regulation of translational initiationGO:004594840.997
cellular response to interleukin 18GO:007135130.997
nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043160.997
antimicrobial peptide biosynthetic processGO:000277720.997
positive regulation of cellular amine metabolic processGO:003324050.997
regulation of cellular amino acid metabolic processGO:000652150.996
positive regulation of endopeptidase activityGO:0010950430.996
regulation of defense responseGO:00313472330.996
alpha beta t cell differentiation involved in immune responseGO:0002293300.996
regulation of interleukin 12 productionGO:0032655300.996
regulation of protein targetingGO:1903533610.996
positive regulation of apoptotic processGO:00430652170.996
growth involved in symbiotic interactionGO:0044110230.996
regulation of lymphocyte differentiationGO:00456191070.996
positive regulation of jun kinase activityGO:0043507300.996
Mouse
positive regulation of cytokine productionGO:00018191740.996
regulation of interleukin 13 secretionGO:200066520.996
positive regulation of protein localization to nucleusGO:1900182300.996
glial cell apoptotic processGO:003434930.996
t cell differentiation involved in immune responseGO:0002292300.995
inflammatory responseGO:00069542440.995
positive regulation of programmed cell deathGO:00430682180.995
positive regulation of t cell activationGO:00508701010.995
Mouse
cytokine biosynthetic processGO:0042089680.995
defense response to gram positive bacteriumGO:0050830500.995
myeloid leukocyte activationGO:0002274830.995
regulation of translational initiation by ironGO:000644720.995
positive regulation of b cell mediated immunityGO:0002714260.995
lymphocyte differentiationGO:00300982420.995
Mouse
nik nf kappab signalingGO:0038061140.995
interleukin 13 secretionGO:007261120.995
regulation of tumor necrosis factor productionGO:0032680490.995
regulation of fatty acid transportGO:2000191100.995
Mouse
prostaglandin transportGO:001573270.995
Mouse
positive regulation of mapk cascadeGO:00434101700.995
positive regulation of antimicrobial peptide biosynthetic processGO:000280710.995
cytoplasmic pattern recognition receptor signaling pathwayGO:0002753100.995
regulation of reactive oxygen species metabolic processGO:2000377400.994
positive regulation of protein kinase b signalingGO:0051897320.994
regulation of t helper 1 cell differentiationGO:004562570.994
positive regulation of protein modification processGO:00314012990.994
Mouse
chemokine biosynthetic processGO:004203380.994
cellular amine metabolic processGO:0044106440.993
interleukin 18 mediated signaling pathwayGO:003565520.993
protein importGO:00170381010.993
regulation of transcription factor import into nucleusGO:0042990240.993
positive regulation of map kinase activityGO:0043406840.993
Mouse
positive regulation of fever generation by positive regulation of prostaglandin secretionGO:007181220.993
Mouse
tyrosine phosphorylation of stat proteinGO:0007260230.993
t helper 2 cell differentiationGO:0045064120.993
positive regulation of protein phosphorylationGO:00019342420.993
Mouse
positive regulation of defense response to bacteriumGO:190042610.993
positive regulation of immune effector processGO:00026991070.992
t cell differentiationGO:00302171740.992
regulation of cd4 positive alpha beta t cell differentiationGO:0043370210.992
alpha beta t cell proliferationGO:0046633210.992
regulation of t cell activationGO:00508631700.992
Mouse
regulation of intracellular transportGO:00323861590.992
t cell receptor signaling pathwayGO:0050852460.992
chemokine productionGO:0032602340.992
regulation of leukocyte differentiationGO:19021051590.992
regulation of immunoglobulin mediated immune responseGO:0002889370.992
alpha beta t cell differentiationGO:0046632690.991
regulation of protein localizationGO:00328802310.991
positive regulation of osteoclast differentiationGO:0045672150.991
Mouse
activation of innate immune responseGO:0002218560.991
regulation of cytokine productionGO:00018172660.991
response to molecule of bacterial originGO:00022371430.991
negative regulation of interleukin 5 productionGO:003271440.991
heat generationGO:0031649130.990
regulation of jnk cascadeGO:0046328620.990
apoptotic signaling pathwayGO:00971903060.990
regulation of humoral immune responseGO:0002920220.990
protein localization to nucleusGO:00345041210.990
positive regulation of protein serine threonine kinase activityGO:00719021060.990
Mouse
somatic diversification of immunoglobulinsGO:0016445430.990
Mouse
positive regulation of lymphocyte mediated immunityGO:0002708620.990
positive regulation of lipid transportGO:0032370220.989
Mouse
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.989
b cell activationGO:00421131610.989
Mouse
positive regulation of t cell proliferationGO:0042102520.989
mammary gland lobule developmentGO:0061377220.989
Mouse
nuclear importGO:0051170950.988
immune response activating signal transductionGO:00027571160.988
regulation of icosanoid secretionGO:003230380.988
Mouse
positive regulation of chemokine biosynthetic processGO:004508060.988
regulation of immunoglobulin productionGO:0002637420.987
negative regulation of necrotic cell deathGO:0060547110.987
growth of symbiont in hostGO:0044117230.987
cytoplasmic transportGO:00164822340.986
temperature homeostasisGO:0001659260.986
t helper 2 cell cytokine productionGO:003574540.985
regulation of b cell mediated immunityGO:0002712370.984
somatic cell dna recombinationGO:0016444510.984
Mouse
positive regulation of b cell activationGO:0050871490.984
positive regulation of cell activationGO:00508671580.984
Mouse
negative regulation of growth of symbiont involved in interaction with hostGO:0044146190.984
amine metabolic processGO:0009308450.983
myeloid leukocyte differentiationGO:00025731190.983
regulation of t helper cell differentiationGO:0045622140.983
somatic recombination of immunoglobulin gene segmentsGO:0016447420.983
Mouse
negative regulation of cytokine productionGO:0001818840.983
dna recombinationGO:0006310920.982
Mouse
pattern recognition receptor signaling pathwayGO:0002221470.982
circadian rhythmGO:00076231140.982
cellular amino acid metabolic processGO:00065201030.982
isotype switchingGO:0045190360.981
Mouse
positive regulation of icosanoid secretionGO:003230570.981
Mouse
regulation of nucleocytoplasmic transportGO:0046822730.981
regulation of cellular amine metabolic processGO:0033238200.981
lymphocyte migrationGO:0072676260.980
Mouse
regulation of stress activated mapk cascadeGO:0032872690.980
cellular response to dna damage stimulusGO:00069742070.980
negative regulation of interleukin 13 secretionGO:200066610.980
positive regulation of antimicrobial peptide productionGO:000222510.979
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919270.979
regulation of prostaglandin secretionGO:003230650.979
Mouse
immune response activating cell surface receptor signaling pathwayGO:0002429720.978
negative regulation of odontogenesis of dentin containing toothGO:004248910.978
reactive nitrogen species metabolic processGO:200105700.978
lymphocyte homeostasisGO:0002260640.978
alpha beta t cell activation involved in immune responseGO:0002287310.978
positive regulation of acute inflammatory responseGO:0002675160.977
regulation of t cell differentiationGO:0045580830.977
regulation of apoptotic signaling pathwayGO:20012331970.976
negative regulation of adaptive immune responseGO:0002820250.976
gland developmentGO:00487323300.976
osteoclast differentiationGO:0030316620.976
regulation of interleukin 5 secretionGO:200066220.976
regulation of protein import into nucleusGO:0042306520.976
regulation of production of molecular mediator of immune responseGO:0002700650.976
myeloid cell differentiationGO:00300992330.975
cd4 positive alpha beta t cell cytokine productionGO:003574340.975
b cell mediated immunityGO:0019724710.975
regulation of corticotropin releasing hormone secretionGO:004339720.975
Mouse
regulation of peptidase activityGO:0052547960.975
negative regulation of hydrolase activityGO:0051346710.974
regulation of adaptive immune responseGO:0002819900.974
positive regulation of cytokine biosynthetic processGO:0042108400.972
symbiosis encompassing mutualism through parasitismGO:0044403830.972
response to interleukin 1GO:0070555110.972
regulation of interferon gamma productionGO:0032649570.972
regulation of transferase activityGO:00513382630.972
Mouse
positive regulation of lymphocyte migrationGO:2000403110.971
Mouse
positive regulation of antimicrobial humoral responseGO:000276020.971
interferon beta biosynthetic processGO:004535040.970
positive regulation of interleukin 6 productionGO:0032755370.970
regulation of interleukin 10 productionGO:0032653210.970
regulation of anion transportGO:0044070270.969
Mouse Rat
b cell proliferationGO:0042100530.969
negative regulation of glucose transportGO:001082990.969
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.968
negative regulation of interleukin 5 secretionGO:200066310.968
defense response to virusGO:0051607680.968
t helper 1 cell differentiationGO:0045063130.967
immune effector processGO:00022523210.967
immune response regulating cell surface receptor signaling pathwayGO:0002768800.965
corticotropin releasing hormone secretionGO:004339620.965
Mouse
t cell activation involved in immune responseGO:0002286430.965
positive regulation of t helper 1 cell differentiationGO:004562740.965
positive regulation of jnk cascadeGO:0046330460.964
dna metabolic processGO:00062593030.964
Mouse
positive regulation of humoral immune responseGO:0002922110.964
regulation of toll like receptor 2 signaling pathwayGO:003413530.964
nuclear transportGO:00511691390.964
regulation of alpha beta t cell proliferationGO:0046640180.963
regulation of interleukin 10 secretionGO:200117940.963
positive regulation of cytokine production involved in immune responseGO:0002720190.962
dephosphorylationGO:00163111290.962
negative regulation of growthGO:0045926990.962
positive regulation of apoptotic signaling pathwayGO:2001235950.962
regulation of protein kinase activityGO:00458592320.961
Mouse
regulation of lymphocyte mediated immunityGO:0002706840.961
humoral immune response mediated by circulating immunoglobulinGO:0002455140.960
cytokine metabolic processGO:0042107710.960
stress activated mapk cascadeGO:0051403800.959
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239260.958
intrinsic apoptotic signaling pathwayGO:00971931320.958
regulation of b cell activationGO:0050864810.956
positive regulation of interleukin 10 productionGO:0032733120.956
positive regulation of t cell migrationGO:2000406100.955
Mouse
positive regulation of myeloid leukocyte differentiationGO:0002763260.955
Mouse
isotype switching to igg isotypesGO:0048291100.955
regulation of establishment of protein localizationGO:00702011810.954
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.954
positive regulation of nf kappab transcription factor activityGO:0051092300.953
negative regulation of inflammatory responseGO:0050728610.952
t cell selectionGO:0045058340.952
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.951
negative regulation of t helper 2 cell differentiationGO:004562940.951
regulation of lymphocyte activationGO:00512492400.951
Mouse
positive regulation of transferase activityGO:00513471670.948
Mouse
regulation of innate immune responseGO:0045088910.948
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.947
regulation of antigen receptor mediated signaling pathwayGO:0050854290.947
single organism nuclear importGO:1902593950.947
negative regulation of phosphorus metabolic processGO:00105631840.946
positive regulation of organic acid transportGO:0032892110.945
Mouse
positive regulation of osteoclast developmentGO:200120630.945
Mouse
positive regulation of peptidase activityGO:0010952490.944
regulation of multi organism processGO:00439001110.944
protein targetingGO:00066051430.943
t helper 1 type immune responseGO:0042088250.942
positive regulation of protein kinase activityGO:00458601440.941
Mouse
lymphocyte proliferationGO:00466511640.940
cell fate commitmentGO:00451652100.940
Fly
regulation of cytokine secretionGO:0050707610.939
regulation of symbiosis encompassing mutualism through parasitismGO:0043903520.937
regulation of protein transportGO:00512231630.935
regulation of peptidyl tyrosine phosphorylationGO:0050730930.935
jak stat cascadeGO:0007259420.935
positive regulation of immunoglobulin mediated immune responseGO:0002891260.935
necrotic cell deathGO:0070265300.935
positive regulation of reactive oxygen species metabolic processGO:2000379110.934
regulation of protein secretionGO:0050708820.934
protein import into nucleusGO:0006606950.934
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.933
positive regulation of secretion by cellGO:19035321140.933
Mouse
positive regulation of mhc class ii biosynthetic processGO:004534840.932
zymogen activationGO:0031638410.932
positive regulation of leukocyte differentiationGO:1902107860.932
Mouse
nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042750.932
regulation of lymphocyte migrationGO:2000401140.932
Mouse
response to organic cyclic compoundGO:00140701980.931
Zebrafish
t cell chemotaxisGO:001081860.930
Mouse
interferon gamma productionGO:0032609670.930
transcription factor import into nucleusGO:0042991260.930
regulation of mhc class ii biosynthetic processGO:004534670.930
regulation of ion transportGO:00432692150.928
Mouse Rat
response to organonitrogen compoundGO:00102432460.928
positive regulation of innate immune responseGO:0045089800.928
dendritic cell differentiationGO:0097028260.925
mapk cascadeGO:00001652810.925
regulation of reactive oxygen species biosynthetic processGO:190342620.923
lymphocyte chemotaxisGO:0048247100.923
Mouse
stress activated protein kinase signaling cascadeGO:0031098810.922
positive regulation of t cell differentiationGO:0045582520.922
regulation of defense response to virus by hostGO:005069180.919
negative regulation of alpha beta t cell activationGO:0046636180.919
t cell proliferationGO:00420981200.919
positive regulation of stress activated mapk cascadeGO:0032874480.916
regulation of secretionGO:00510462740.912
positive regulation of corticotropin releasing hormone secretionGO:005146610.911
Mouse
positive regulation of protein transportGO:0051222930.910
interleukin 6 biosynthetic processGO:0042226120.910
cellular response to organonitrogen compoundGO:00714171450.907
cytokine secretion involved in immune responseGO:000237460.906
regulation of mapk cascadeGO:00434082480.905
regulation of kinase activityGO:00435492490.903
Mouse
positive regulation of kinase activityGO:00336741550.901
Mouse
peptidyl tyrosine modificationGO:00182121450.900
positive regulation of ion transportGO:0043270650.900
Mouse
negative regulation of alkaline phosphatase activityGO:001069330.900
nucleocytoplasmic transportGO:00069131390.900
regulation of hydrolase activityGO:00513362460.899
negative regulation of defense responseGO:0031348770.898
interspecies interaction between organismsGO:0044419830.898
tyrosine phosphorylation of stat1 proteinGO:004250830.897
regulation of antimicrobial peptide productionGO:000278410.896
regulation of type 2 immune responseGO:0002828180.896
regulation of interleukin 6 biosynthetic processGO:0045408110.895
regulation of cytoplasmic transportGO:19036491120.894
negative regulation of b cell proliferationGO:0030889130.893
regulation of t cell proliferationGO:0042129920.889
positive regulation of hair follicle developmentGO:005179860.888
innate immune response activating signal transductionGO:0002758500.887
intracellular protein transportGO:00068862040.887
positive regulation of inflammatory responseGO:0050729470.887
regulation of jak stat cascadeGO:0046425340.884
regulation of translationGO:0006417710.883
metal ion homeostasisGO:00550651890.883
Mouse
activation of jun kinase activityGO:0007257150.883
Mouse
organic acid transportGO:00158491010.881
Mouse Rat
response to interleukin 18GO:007067340.881
negative regulation of molecular functionGO:00440922580.880
positive regulation of intracellular protein transportGO:0090316420.880
fatty acid transportGO:0015908280.880
Mouse
negative regulation of map kinase activityGO:0043407340.879
b cell differentiationGO:0030183780.878
Mouse
myeloid dendritic cell activationGO:0001773250.878
positive regulation of myeloid cell differentiationGO:0045639430.878
Mouse
jnk cascadeGO:0007254720.877
positive regulation of prostaglandin secretionGO:003230850.877
Mouse
establishment of protein localization to organelleGO:00725941180.877
leukocyte migrationGO:00509001240.876
regulation of cytokine secretion involved in immune responseGO:000273940.875
translationGO:0006412930.874
response to amino acidGO:0043200370.873
toll like receptor 4 signaling pathwayGO:003414290.873
negative regulation of chronic inflammatory responseGO:000267730.871
regulation of jun kinase activityGO:0043506400.869
Mouse
tumor necrosis factor productionGO:0032640500.868
negative regulation of t helper 1 cell differentiationGO:004562630.867
epithelial cell proliferation involved in salivary gland morphogenesisGO:006066470.866
inflammatory response to antigenic stimulusGO:0002437300.864
activation of immune responseGO:00022531380.862
leukocyte proliferationGO:00706611720.862
Mouse
germinal center formationGO:0002467160.860
regulation of protein localization to nucleusGO:1900180600.859
peptide transportGO:00158331330.859
positive regulation of translationGO:0045727190.859
positive regulation of cysteine type endopeptidase activityGO:2001056390.858
t cell migrationGO:0072678190.856
Mouse
positive regulation of isotype switchingGO:0045830150.855
cdc42 protein signal transductionGO:003248800.855
negative regulation of interleukin 12 productionGO:0032695100.851
exocrine system developmentGO:0035272450.849
positive regulation of cd8 positive alpha beta t cell extravasationGO:200045120.848
regulation of osteoclast differentiationGO:0045670360.842
positive regulation of protein import into nucleusGO:0042307260.842
regulation of proteolysisGO:00301621640.840
positive regulation of hydrolase activityGO:00513451480.839
regulation of cell migrationGO:00303342190.839
Mouse
prostaglandin secretionGO:003231050.836
Mouse
positive regulation of muscle cell differentiationGO:0051149390.834
Mouse
glucose transportGO:0015758560.832
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002823230.832
positive regulation of cytokine secretionGO:0050715410.830
positive regulation of cytoplasmic transportGO:1903651400.830
positive regulation of humoral immune response mediated by circulating immunoglobulinGO:000292560.828
response to dsrnaGO:0043331300.827
Zebrafish
leukocyte apoptotic processGO:0071887710.825
activation of cysteine type endopeptidase activityGO:0097202270.823
negative regulation of apoptotic signaling pathwayGO:20012341040.822
positive regulation of defense response to virus by hostGO:000223060.819
carboxylic acid transportGO:00469421000.819
Mouse Rat
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.817
positive regulation of response to woundingGO:1903036660.817
innate immune responseGO:00450871570.817
Fly
regulation of interleukin 2 productionGO:0032663280.815
positive regulation of tyrosine phosphorylation of stat proteinGO:0042531150.815
defense response to fungusGO:0050832120.814
regulation of isotype switching to igg isotypesGO:0048302100.813
cation homeostasisGO:00550802120.812
Mouse
regulation of tumor necrosis factor biosynthetic processGO:0042534100.811
regulation of intracellular protein transportGO:0033157820.811
positive regulation of cell developmentGO:00107202370.811
Mouse
regulation of vitamin d biosynthetic processGO:006055610.810
regulation of endopeptidase activityGO:0052548890.808
negative regulation of protein metabolic processGO:00512482820.807
icosanoid transportGO:0071715140.807
Mouse
osteoclast developmentGO:003603590.804
Mouse
positive regulation of monocyte chemotaxisGO:009002620.803
regulation of isotype switchingGO:0045191220.800
positive regulation of interleukin 1 secretionGO:0050716140.800
regulation of cellular response to stressGO:00801351590.794
positive regulation of tyrosine phosphorylation of stat1 proteinGO:004251110.793
regulation of heat generationGO:003165080.793
inflammatory cell apoptotic processGO:0006925110.787
negative regulation of interleukin 13 productionGO:003269620.784
regulation of chemokine biosynthetic processGO:004507380.783
monosaccharide transportGO:0015749580.783
acute phase responseGO:0006953100.782
myeloid dendritic cell differentiationGO:0043011160.782
eosinophil degranulationGO:004330810.781
positive regulation of glial cell proliferationGO:006025240.780
cellular ketone metabolic processGO:0042180840.779
t cell differentiation in thymusGO:0033077770.779
cell chemotaxisGO:0060326810.779
Mouse
negative regulation of immune system processGO:00026832090.776
regulation of immunoglobulin secretionGO:0051023120.775
organ or tissue specific immune responseGO:0002251130.774
negative regulation of interleukin 6 productionGO:0032715170.771
regulation of lipid transportGO:0032368360.768
Mouse
fatty acid derivative transportGO:1901571140.766
Mouse
t helper 17 cell lineage commitmentGO:007254040.765
mammary gland epithelial cell proliferationGO:0033598240.764
Mouse
toll like receptor signaling pathwayGO:0002224380.762
anion transportGO:00068201770.760
Mouse Rat
mammary gland alveolus developmentGO:0060749220.757
Mouse
translational initiationGO:0006413240.755
negative regulation of cell activationGO:00508661110.754
positive regulation of hair cycleGO:004263570.753
positive regulation of cytokine secretion involved in immune responseGO:000274120.752
production of molecular mediator involved in inflammatory responseGO:0002532210.751
positive regulation of interleukin 6 biosynthetic processGO:004541060.751
regulation of branching involved in salivary gland morphogenesisGO:0060693110.750
positive regulation of heat generationGO:003165270.747
signal transduction in absence of ligandGO:0038034550.747
compound eye developmentGO:004874910.742
branching involved in salivary gland morphogenesisGO:0060445260.736
positive regulation of peptidyl tyrosine phosphorylationGO:0050731610.735
regulation of homeostatic processGO:00328441820.733

Tnf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org