Mus musculus

27 known processes

Tpi1

triosephosphate isomerase 1

(Aliases: AI255506,Tpi-1,Tpi)

Tpi1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
pyruvate metabolic processGO:0006090280.999
Fly
glycolytic processGO:0006096200.999
Fly
ribonucleoside monophosphate biosynthetic processGO:000915690.996
hexose catabolic processGO:001932030.996
carbohydrate catabolic processGO:0016052320.989
Fly
generation of precursor metabolites and energyGO:00060911030.984
Fly
apoptotic mitochondrial changesGO:0008637480.911
atp metabolic processGO:0046034750.910
ribose phosphate biosynthetic processGO:0046390590.887
monocarboxylic acid metabolic processGO:00327871910.887
Fly
lactate biosynthetic processGO:001924940.874
hexose metabolic processGO:0019318980.836
carboxylic acid biosynthetic processGO:0046394860.824
monosaccharide metabolic processGO:00059961060.815
carbohydrate metabolic processGO:00059752300.761
purine nucleoside biosynthetic processGO:0042451190.748
nucleoside metabolic processGO:00091162460.684
myosin filament organizationGO:003103330.672
Worm
purine nucleoside monophosphate biosynthetic processGO:000912790.671
sperm motilityGO:0030317470.662
ribonucleoside triphosphate metabolic processGO:00091992200.643
ribonucleoside monophosphate metabolic processGO:0009161800.613
purine ribonucleoside biosynthetic processGO:0046129190.613
purine nucleoside triphosphate metabolic processGO:00091442260.609
pentose phosphate shuntGO:000609820.606
purine ribonucleotide metabolic processGO:00091502900.606
nucleotide metabolic processGO:00091173320.603
purine nucleotide biosynthetic processGO:0006164650.593
purine ribonucleotide biosynthetic processGO:0009152590.579
oxidation reduction processGO:00551143420.575
purine ribonucleoside monophosphate metabolic processGO:0009167800.570
purine containing compound metabolic processGO:00725213110.558
response to hypoxiaGO:0001666580.529
nucleoside phosphate metabolic processGO:00067533380.502
purine nucleoside monophosphate metabolic processGO:0009126810.459
carbohydrate derivative biosynthetic processGO:19011371830.446
nucleoside biosynthetic processGO:0009163210.441
nucleoside monophosphate metabolic processGO:0009123850.433
response to decreased oxygen levelsGO:0036293590.431
ribonucleoside biosynthetic processGO:0042455210.399
purine nucleoside metabolic processGO:00422782410.390
ribonucleotide metabolic processGO:00092592910.376
nucleoside phosphate biosynthetic processGO:1901293790.376
nadph regenerationGO:000674020.353
nucleobase containing small molecule metabolic processGO:00550863520.343
nitrogen compound transportGO:00717052710.341
purine ribonucleoside metabolic processGO:00461282410.311
purine nucleoside triphosphate biosynthetic processGO:000914570.309
nucleoside triphosphate metabolic processGO:00091412300.305
glucose catabolic processGO:000600730.303
glycosyl compound biosynthetic processGO:1901659210.277
purine containing compound biosynthetic processGO:0072522700.240
purine nucleotide metabolic processGO:00061633020.230
substantia nigra developmentGO:002176220.220
neural nucleus developmentGO:0048857220.219
ribose phosphate metabolic processGO:00196932910.215
energy derivation by oxidation of organic compoundsGO:0015980770.215
carbohydrate phosphorylationGO:0046835150.215
organic hydroxy compound biosynthetic processGO:1901617770.211
cellular aldehyde metabolic processGO:0006081120.199
negative regulation of cellular protein metabolic processGO:00322692470.194
cellular response to external stimulusGO:0071496880.187
response to oxygen levelsGO:0070482620.173
glucose homeostasisGO:00425931280.170
cellular response to extracellular stimulusGO:0031668810.165
positive regulation of apoptotic processGO:00430652170.150
cellular amino acid metabolic processGO:00065201030.148
response to nicotineGO:003509460.145
hormone secretionGO:00468791280.142
ribonucleotide biosynthetic processGO:0009260590.142
amide transportGO:00428861380.138
organonitrogen compound biosynthetic processGO:19015661920.133
glycosyl compound metabolic processGO:19016572460.133
mesoderm morphogenesisGO:0048332640.131
cellular homeostasisGO:00197252400.120
Worm
purine ribonucleoside triphosphate metabolic processGO:00092052200.114
purine ribonucleoside monophosphate biosynthetic processGO:000916890.113
insulin secretionGO:0030073890.112
regulation of hormone levelsGO:00108172110.112
pigmentationGO:0043473710.106
monosaccharide catabolic processGO:004636550.099
regulation of peptide secretionGO:0002791770.098
nucleoside monophosphate biosynthetic processGO:0009124120.094
cellular response to dna damage stimulusGO:00069742070.092
somitogenesisGO:0001756690.092
lipid localizationGO:00108761260.089
organic hydroxy compound metabolic processGO:19016152030.086
muscle contractionGO:00069361010.085
regulation of cell cycleGO:00517262810.079
formation of primary germ layerGO:0001704770.077
mesoderm formationGO:0001707620.075
regulation of translationGO:0006417710.074
negative regulation of cell cycle phase transitionGO:1901988480.073
midbrain developmentGO:0030901350.072
monocarboxylic acid biosynthetic processGO:0072330610.070
carbohydrate biosynthetic processGO:0016051740.070
positive regulation of hormone secretionGO:0046887380.070
response to organic cyclic compoundGO:00140701980.066
ribonucleoside metabolic processGO:00091192450.065
mitotic cell cycleGO:00002781950.065
ribonucleoside triphosphate biosynthetic processGO:000920160.064
regulation of peptide transportGO:0090087910.063
negative regulation of protein metabolic processGO:00512482820.058
mitotic cell cycle checkpointGO:0007093310.056
apoptotic signaling pathwayGO:00971903060.056
anatomical structure homeostasisGO:00602491450.056
positive regulation of growthGO:00459271040.056
regulation of cellular amino acid metabolic processGO:000652150.053
regulation of coenzyme metabolic processGO:005119640.052
regulation of cellular amine metabolic processGO:0033238200.051
alpha amino acid metabolic processGO:1901605590.051
negative regulation of mitotic cell cycleGO:0045930580.050
nucleotide biosynthetic processGO:0009165780.050
regulation of mitotic cell cycleGO:00073461260.050
organophosphate biosynthetic processGO:00904071220.049
response to estrogenGO:0043627240.049
fructose 6 phosphate metabolic processGO:000600210.048
oxidoreduction coenzyme metabolic processGO:0006733160.048
response to heatGO:0009408270.047
regulation of membrane potentialGO:00423911920.047
muscle system processGO:00030121410.046
protein targetingGO:00066051430.046
striated muscle contractionGO:0006941450.046
positive regulation of cellular amino acid metabolic processGO:004576430.046
positive regulation of peptide secretionGO:0002793330.046
carbohydrate homeostasisGO:00335001280.044
protein catabolic processGO:00301632210.042
positive regulation of programmed cell deathGO:00430682180.042
cellular amine metabolic processGO:0044106440.041
regulation of cellular catabolic processGO:00313292420.040
multi multicellular organism processGO:00447061090.040
cellular modified amino acid metabolic processGO:0006575630.040
purine ribonucleoside triphosphate biosynthetic processGO:000920660.040
gluconeogenesisGO:0006094390.040
maintenance of locationGO:0051235890.040
response to oxidative stressGO:00069791230.039
nucleoside triphosphate biosynthetic processGO:000914280.038
positive regulation of cell deathGO:00109422240.038
organic acid biosynthetic processGO:0016053860.038
negative regulation of molecular functionGO:00440922580.037
myeloid cell homeostasisGO:00022621140.037
activation of cysteine type endopeptidase activityGO:0097202270.036
monosaccharide biosynthetic processGO:0046364440.036
positive regulation of apoptotic signaling pathwayGO:2001235950.036
response to inorganic substanceGO:0010035960.035
negative regulation of cell cycleGO:00457861230.035
male gamete generationGO:00482322850.035
reactive oxygen species metabolic processGO:0072593840.034
spermatogenesisGO:00072832840.034
cellular carbohydrate catabolic processGO:0044275150.033
aromatic compound catabolic processGO:00194392860.033
inorganic cation transmembrane transportGO:00986622070.032
response to organonitrogen compoundGO:00102432460.031
cellular amide metabolic processGO:0043603580.031
transmembrane transportGO:00550854120.030
regulation of cellular ketone metabolic processGO:0010565660.030
striated muscle myosin thick filament assemblyGO:007168810.030
Worm
amine metabolic processGO:0009308450.030
regulation of glycolytic processGO:0006110100.029
defecationGO:003042110.029
glucose metabolic processGO:0006006920.029
regulation of protein kinase activityGO:00458592320.029
regulation of apoptotic signaling pathwayGO:20012331970.028
regulation of proteolysisGO:00301621640.028
regulation of organelle organizationGO:00330432890.028
placenta developmentGO:00018901400.027
regulation of purine nucleotide metabolic processGO:19005421690.027
cytoplasmic transportGO:00164822340.027
determination of adult lifespanGO:0008340110.027
Worm Fly
negative regulation of peptide secretionGO:0002792160.027
homeostasis of number of cellsGO:00488722100.026
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.026
intrinsic apoptotic signaling pathwayGO:00971931320.026
heterocycle catabolic processGO:00467002800.025
intracellular protein transportGO:00068862040.024
positive regulation of cellular amine metabolic processGO:003324050.024
cofactor metabolic processGO:0051186800.024
regulation of nucleotide metabolic processGO:00061401690.024
protein processingGO:00164851630.024
regulation of hydrolase activityGO:00513362460.023
regulation of endopeptidase activityGO:0052548890.023
release of cytochrome c from mitochondriaGO:0001836230.023
genitalia developmentGO:0048806370.023
regulation of release of cytochrome c from mitochondriaGO:0090199110.023
myofibril assemblyGO:0030239340.023
Worm
muscle cell developmentGO:00550011330.023
Worm
chromatin organizationGO:00063252060.022
neuron neuron synaptic transmissionGO:0007270690.022
response to lipopolysaccharideGO:00324961280.022
organonitrogen compound catabolic processGO:19015652640.022
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.022
protein modification by small protein conjugationGO:00324461870.022
small molecule biosynthetic processGO:00442831320.022
sulfur compound metabolic processGO:00067901000.021
regulation of cofactor metabolic processGO:005119350.021
positive regulation of hydrolase activityGO:00513451480.021
protein ubiquitinationGO:00165671710.021
negative regulation of phosphorus metabolic processGO:00105631840.021
neuron apoptotic processGO:00514021420.021
regulation of reactive oxygen species biosynthetic processGO:190342620.021
positive regulation of peptide hormone secretionGO:0090277310.021
ribonucleoside catabolic processGO:00424542060.020
t cell activationGO:00421102890.020
cation transmembrane transportGO:00986552660.020
cation homeostasisGO:00550802120.020
cellular divalent inorganic cation homeostasisGO:00725031270.020
regulation of interleukin 8 productionGO:003267730.020
proton transportGO:0015992350.020
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.020
regulation of neuron apoptotic processGO:00435231220.020
aldehyde catabolic processGO:004618540.020
mitochondrion organizationGO:00070051340.020
regulation of transferase activityGO:00513382630.020
regulation of protein serine threonine kinase activityGO:00719001570.020
regulation of cell cycle phase transitionGO:1901987770.020
regulation of protein localizationGO:00328802310.019
skin developmentGO:00435882200.019
regulation of nucleoside metabolic processGO:00091181300.019
gonad developmentGO:00084061410.019
digestive tract morphogenesisGO:00485461470.018
regulation of lymphocyte activationGO:00512492400.018
cellular lipid metabolic processGO:00442553230.018
neuron deathGO:00709971540.018
regionalizationGO:00030023370.018
regulation of cell activationGO:00508652890.017
somite developmentGO:0061053810.017
galactose metabolic processGO:000601240.017
cation transportGO:00068123990.017
nucleotide sugar metabolic processGO:000922540.017
regulation of oxidative phosphorylation uncoupler activityGO:200027530.017
nucleoside phosphate catabolic processGO:19012922220.017
cellular ion homeostasisGO:00068731650.017
nadp metabolic processGO:000673960.017
dopamine uptake involved in synaptic transmissionGO:005158340.017
regulation of cell shapeGO:0008360390.016
energy reserve metabolic processGO:0006112390.016
macromolecule catabolic processGO:00090572810.016
carbohydrate derivative catabolic processGO:19011362310.016
regulation of leukocyte proliferationGO:00706631210.016
positive regulation of nucleoside metabolic processGO:0045979910.016
regulation of cell cycle processGO:00105641600.016
nuclear transportGO:00511691390.016
cell type specific apoptotic processGO:00972852680.016
epithelial cell developmentGO:00020641590.016
positive regulation of reactive oxygen species metabolic processGO:2000379110.016
protein oligomerizationGO:0051259670.016
regulation of response to woundingGO:19030341890.015
cellular nitrogen compound catabolic processGO:00442702800.015
regulation of ion transportGO:00432692150.015
inorganic ion transmembrane transportGO:00986602340.015
negative regulation of cell cycle processGO:0010948690.015
metal ion homeostasisGO:00550651890.015
epithelial tube morphogenesisGO:00605623030.015
regulation of chromatin modificationGO:1903308570.015
mesoderm developmentGO:00074981000.015
synaptic transmissionGO:00072683290.014
regulation of cytokine productionGO:00018172660.014
endomembrane system organizationGO:00102561470.014
regulation of cysteine type endopeptidase activityGO:2000116650.014
mitotic cell cycle processGO:19030471590.014
response to steroid hormoneGO:0048545560.014
regulation of glucose metabolic processGO:0010906600.014
regulation of secretionGO:00510462740.014
positive regulation of proteolysisGO:0045862850.014
protein maturationGO:00516041760.014
protein modification by small protein conjugation or removalGO:00706472070.014
regulation of nucleocytoplasmic transportGO:0046822730.014
t cell proliferationGO:00420981200.014
lymphocyte proliferationGO:00466511640.014
regulation of secretion by cellGO:19035302490.014
fat cell differentiationGO:00454441600.014
g0 to g1 transitionGO:004502330.014
leukocyte proliferationGO:00706611720.013
positive regulation of cysteine type endopeptidase activityGO:2001056390.013
organic hydroxy compound transportGO:0015850930.013
alcohol metabolic processGO:00060661160.013
hydrogen transportGO:0006818350.013
regulation of transmembrane transportGO:00347621280.013
regulation of oxidative phosphorylationGO:000208260.013
removal of superoxide radicalsGO:0019430120.013
cellular respirationGO:0045333380.013
divalent metal ion transportGO:00708381720.013
cellular ketone metabolic processGO:0042180840.013
purine nucleoside triphosphate catabolic processGO:00091462030.013
purine ribonucleoside triphosphate catabolic processGO:00092071990.013
regulation of bindingGO:00510981110.013
modification dependent macromolecule catabolic processGO:00436321330.013
reactive oxygen species biosynthetic processGO:190340980.013
regulation of chromosome organizationGO:0033044830.013
epithelial cell proliferationGO:00506731740.013
cellular carbohydrate metabolic processGO:00442621190.013
positive regulation of protein modification processGO:00314012990.013
peptidyl amino acid modificationGO:00181933360.013
wound healingGO:00420601570.013
response to temperature stimulusGO:0009266550.013
protein deacetylationGO:0006476320.013
cellular component assembly involved in morphogenesisGO:00109271390.013
Worm
regulation of transporter activityGO:0032409570.013
fructose metabolic processGO:000600010.013
response to extracellular stimulusGO:00099911270.012
cell fate commitmentGO:00451652100.012
negative regulation of phosphorylationGO:00423261660.012
regulation of peptidase activityGO:0052547960.012
negative regulation of neuron apoptotic processGO:0043524920.012
peptide transportGO:00158331330.012
regulation of t cell activationGO:00508631700.012
compound eye developmentGO:004874910.012
peptide hormone secretionGO:00300721090.012
negative regulation of translationGO:0017148220.012
negative regulation of protein modification processGO:00314001630.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
regulation of androgen receptor signaling pathwayGO:006076530.012
positive regulation of bindingGO:0051099490.012
ion transmembrane transportGO:00342203610.011
purine nucleotide catabolic processGO:00061952110.011
positive regulation of kinase activityGO:00336741550.011
positive regulation of protein phosphorylationGO:00019342420.011
regulation of purine nucleotide catabolic processGO:00331211220.011
negative regulation of neuron deathGO:1901215980.011
myosin filament assemblyGO:003103420.011
Worm
negative regulation of phosphate metabolic processGO:00459361840.011
protein homotetramerizationGO:0051289120.011
positive regulation of purine nucleotide metabolic processGO:19005441140.011
positive regulation of transferase activityGO:00513471670.011
negative regulation of oxidative stress induced cell deathGO:190320290.011
regulation of mapk cascadeGO:00434082480.011
negative regulation of hydrolase activityGO:0051346710.011
chromatin modificationGO:00165681870.011
purine containing compound catabolic processGO:00725232130.011
regulation of generation of precursor metabolites and energyGO:0043467380.011
lateral inhibitionGO:004633110.011
regulation of establishment of protein localizationGO:00702011810.011
leukocyte differentiationGO:00025213420.011
peptide secretionGO:00027901140.011
peptidyl proline hydroxylationGO:001951130.011
alditol metabolic processGO:001940050.011
mapk cascadeGO:00001652810.010
cellular response to cytokine stimulusGO:00713451890.010
tricarboxylic acid metabolic processGO:007235050.010
organophosphate catabolic processGO:00464342320.010
atp synthesis coupled electron transportGO:004277380.010
inflammatory responseGO:00069542440.010
purine ribonucleoside catabolic processGO:00461302050.010
negative regulation of mitotic cell cycle phase transitionGO:1901991450.010
regulation of neurotransmitter levelsGO:0001505870.010
positive regulation of transmembrane transportGO:0034764290.010
cellular response to organonitrogen compoundGO:00714171450.010
asymmetric stem cell divisionGO:009872230.010
negative regulation of protein phosphorylationGO:00019331260.010
renal system developmentGO:00720012250.010
cell cycle checkpointGO:0000075470.010
histone modificationGO:00165701590.010
translationGO:0006412930.010
negative regulation of transferase activityGO:0051348850.010

Tpi1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.822
immune system diseaseDOID:291400.822
hematopoietic system diseaseDOID:7400.257
anemiaDOID:235500.257
hemolytic anemiaDOID:58300.257
normocytic anemiaDOID:72000.257
nervous system diseaseDOID:86300.113
neurodegenerative diseaseDOID:128900.113
central nervous system diseaseDOID:33100.113
disease of metabolismDOID:001466700.020
Human
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
organ system cancerDOID:005068600.010