Mus musculus

281 known processes

Traf6

TNF receptor-associated factor 6

(Aliases: 2310003F17Rik,C630032O20Rik,AI851288)

Traf6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
toll like receptor signaling pathwayGO:0002224381.000
Mouse
activation of nf kappab inducing kinase activityGO:000725041.000
Human
regulation of stress activated mapk cascadeGO:0032872691.000
Human Mouse
i kappab kinase nf kappab signalingGO:0007249851.000
regulation of sequence specific dna binding transcription factor activityGO:00510901061.000
activation of innate immune responseGO:0002218561.000
Mouse
nik nf kappab signalingGO:0038061141.000
Human
ripoptosome assembly involved in necroptotic processGO:190102661.000
regulation of jnk cascadeGO:0046328620.999
Human Mouse
positive regulation of innate immune responseGO:0045089800.999
Mouse
pattern recognition receptor signaling pathwayGO:0002221470.999
Mouse
jnk cascadeGO:0007254720.999
Human Mouse Rat
cytokine production involved in immune responseGO:0002367340.999
Human
lipopolysaccharide mediated signaling pathwayGO:0031663250.999
activation of immune responseGO:00022531380.999
Human Mouse
negative regulation of nf kappab transcription factor activityGO:0032088150.999
Mouse
regulation of cellular response to stressGO:00801351590.999
Human Mouse
stress activated protein kinase signaling cascadeGO:0031098810.999
Human Mouse Rat
innate immune response activating signal transductionGO:0002758500.998
Mouse
positive regulation of jnk cascadeGO:0046330460.998
Human
regulation of innate immune responseGO:0045088910.998
Mouse
negative regulation of defense responseGO:0031348770.998
regulation of cytokine production involved in immune responseGO:0002718260.998
Human
positive regulation of protein kinase activityGO:00458601440.997
Human
positive regulation of nf kappab transcription factor activityGO:0051092300.997
regulation of defense responseGO:00313472330.996
Mouse
positive regulation of sequence specific dna binding transcription factor activityGO:0051091680.995
regulation of transferase activityGO:00513382630.993
Human
positive regulation of jun kinase activityGO:0043507300.992
Human
regulation of mapk cascadeGO:00434082480.991
Human Mouse
regulation of toll like receptor signaling pathwayGO:0034121200.990
immune response regulating signaling pathwayGO:00027641250.990
Human Mouse
cellular response to lipopolysaccharideGO:0071222770.989
regulation of protein serine threonine kinase activityGO:00719001570.988
Human
positive regulation of map kinase activityGO:0043406840.986
Human
interleukin 13 secretionGO:007261120.984
positive regulation of mapk cascadeGO:00434101700.984
Human
stress activated mapk cascadeGO:0051403800.984
Human Mouse Rat
toll like receptor 4 signaling pathwayGO:003414290.984
positive regulation of protein serine threonine kinase activityGO:00719021060.982
Human
antigen receptor mediated signaling pathwayGO:0050851640.980
Human
immune response activating signal transductionGO:00027571160.978
Human Mouse
regulation of interleukin 10 secretionGO:200117940.978
mapk cascadeGO:00001652810.978
Human Mouse Rat
immune effector processGO:00022523210.975
regulation of kinase activityGO:00435492490.975
Human
lipid transportGO:0006869980.970
positive regulation of kinase activityGO:00336741550.969
Human
negative regulation of sequence specific dna binding transcription factor activityGO:0043433400.963
Mouse
cytokine productionGO:00018163190.963
negative regulation of immune system processGO:00026832090.963
response to lipopolysaccharideGO:00324961280.962
regulation of cytokine productionGO:00018172660.960
regulation of map kinase activityGO:00434051200.960
Human
cellular response to molecule of bacterial originGO:0071219830.958
positive regulation of stress activated mapk cascadeGO:0032874480.957
Human
regulation of interleukin 6 productionGO:0032675550.956
positive regulation of defense responseGO:00313491240.954
Mouse
interleukin 1 mediated signaling pathwayGO:007049840.951
negative regulation of innate immune responseGO:0045824170.950
interleukin 5 secretionGO:007260320.946
interleukin 6 productionGO:0032635580.945
cholesterol transportGO:0030301380.943
cytokine mediated signaling pathwayGO:00192211150.939
tolerance inductionGO:0002507140.938
protein catabolic processGO:00301632210.937
Mouse
positive regulation of transferase activityGO:00513471670.935
Human
positive regulation of protein modification processGO:00314012990.931
Human
positive regulation of tolerance inductionGO:000264580.929
proteolysis involved in cellular protein catabolic processGO:00516031470.927
negative regulation of toll like receptor signaling pathwayGO:0034122140.926
negative regulation of ripoptosome assembly involved in necroptotic processGO:190244330.923
protein modification by small protein conjugation or removalGO:00706472070.921
cellular response to biotic stimulusGO:0071216920.921
cellular response to lipidGO:00713961450.918
protein autophosphorylationGO:0046777610.915
negative regulation of molecular functionGO:00440922580.913
Mouse
interleukin 12 productionGO:0032615320.913
protein polyubiquitinationGO:0000209330.909
regulation of tolerance inductionGO:0002643100.902
response to molecule of bacterial originGO:00022371430.891
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822870.891
Human
interleukin 10 secretionGO:007260840.888
cytoplasmic pattern recognition receptor signaling pathwayGO:0002753100.876
regulation of interleukin 12 productionGO:0032655300.875
negative regulation of intracellular signal transductionGO:19025321670.875
cholesterol effluxGO:0033344240.874
myeloid dendritic cell activationGO:0001773250.872
regulation of jun kinase activityGO:0043506400.871
Human
myd88 independent toll like receptor signaling pathwayGO:000275630.870
negative regulation of kinase activityGO:0033673810.864
macromolecule catabolic processGO:00090572810.861
Mouse
negative regulation of protein serine threonine kinase activityGO:0071901490.848
regulation of lipid transportGO:0032368360.835
apoptotic signaling pathwayGO:00971903060.835
negative regulation of immune effector processGO:0002698550.834
regulation of interleukin 2 productionGO:0032663280.833
Human
negative regulation of cytokine productionGO:0001818840.832
intrinsic apoptotic signaling pathwayGO:00971931320.831
regulation of protein kinase activityGO:00458592320.828
Human
negative regulation of sterol transportGO:003237240.827
positive regulation of protein phosphorylationGO:00019342420.827
Human
regulation of t cell activationGO:00508631700.818
tumor necrosis factor superfamily cytokine productionGO:0071706510.813
cellular protein catabolic processGO:00442571550.809
regulation of lymphocyte activationGO:00512492400.807
regulation of interleukin 5 secretionGO:200066220.801
negative regulation of map kinase activityGO:0043407340.799
regulation of interleukin 13 secretionGO:200066520.792
negative regulation of interleukin 6 productionGO:0032715170.790
regulation of nik nf kappab signalingGO:1901222100.790
Human
regulation of cell activationGO:00508652890.788
cellular macromolecule catabolic processGO:00442652060.786
negative regulation of protein phosphorylationGO:00019331260.781
lymphocyte proliferationGO:00466511640.779
t cell activationGO:00421102890.779
tumor necrosis factor productionGO:0032640500.771
nucleotide binding oligomerization domain containing signaling pathwayGO:007042360.764
cellular response to interleukin 1GO:007134780.764
regulation of adaptive immune responseGO:0002819900.756
Human
ubiquitin dependent protein catabolic processGO:00065111290.742
lymphocyte differentiationGO:00300982420.738
response to dsrnaGO:0043331300.737
protein ubiquitinationGO:00165671710.732
histone modificationGO:00165701590.727
regulation of apoptotic signaling pathwayGO:20012331970.721
positive regulation of nik nf kappab signalingGO:190122470.721
Human
t cell proliferationGO:00420981200.717
positive regulation of interleukin 12 productionGO:0032735210.712
positive regulation of cytokine biosynthetic processGO:0042108400.712
regulation of leukocyte proliferationGO:00706631210.708
cellular amine metabolic processGO:0044106440.701
alpha beta t cell proliferationGO:0046633210.700
positive regulation of apoptotic processGO:00430652170.699
response to interleukin 12GO:007067120.688
response to growth factorGO:00708481980.688
regulation of t cell proliferationGO:0042129920.686
negative regulation of lymphocyte activationGO:0051250910.684
protein modification by small protein conjugationGO:00324461870.673
regulation of alpha beta t cell activationGO:0046634530.670
regulation of tumor necrosis factor productionGO:0032680490.656
regulation of protein complex disassemblyGO:0043244280.656
peptidyl serine modificationGO:0018209830.652
tumor necrosis factor mediated signaling pathwayGO:0033209130.646
Mouse
t helper cell differentiationGO:0042093280.641
negative regulation of necroptotic processGO:006054690.637
cd4 positive alpha beta t cell differentiation involved in immune responseGO:0002294280.637
regulation of lymphocyte mediated immunityGO:0002706840.631
Human
extrinsic apoptotic signaling pathwayGO:00971911260.628
negative regulation of apoptotic signaling pathwayGO:20012341040.624
negative regulation of mapk cascadeGO:0043409650.609
toll like receptor 2 signaling pathwayGO:003413460.607
negative regulation of interleukin 10 secretionGO:200118020.607
necroptotic processGO:0070266210.604
regulation of sterol transportGO:0032371170.597
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824610.595
Human
negative regulation of transferase activityGO:0051348850.593
regulation of necroptotic processGO:0060544100.590
alpha beta t cell differentiation involved in immune responseGO:0002293300.588
cellular response to tumor necrosis factorGO:0071356210.583
Mouse
positive regulation of t cell cytokine productionGO:000272650.576
Human
negative regulation of cytokine production involved in immune responseGO:000271950.574
regulation of leukocyte differentiationGO:19021051590.571
Human
lipid localizationGO:00108761260.568
leukocyte proliferationGO:00706611720.567
modification dependent macromolecule catabolic processGO:00436321330.566
regulation of production of molecular mediator of immune responseGO:0002700650.559
innate immune responseGO:00450871570.555
Zebrafish Mouse
glial cell apoptotic processGO:003434930.552
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555500.550
necrotic cell deathGO:0070265300.545
Mouse
sterol transportGO:0015918380.543
negative regulation of protein modification processGO:00314001630.541
production of molecular mediator of immune responseGO:00024401030.541
alpha beta t cell activationGO:0046631910.537
myeloid cell differentiationGO:00300992330.524
negative regulation of protein catabolic processGO:0042177360.524
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:00024601450.518
leukocyte differentiationGO:00025213420.509
response to peptidoglycanGO:003249490.504
regulation of cholesterol transportGO:0032374170.501
cd4 positive alpha beta t cell differentiationGO:0043367410.493
negative regulation of necrotic cell deathGO:0060547110.493
myeloid dendritic cell differentiationGO:0043011160.486
positive regulation of t cell mediated immunityGO:0002711240.477
Human
lymphocyte apoptotic processGO:0070227540.466
adaptive immune responseGO:00022501550.456
negative regulation of cholesterol transportGO:003237540.453
positive regulation of antibacterial peptide biosynthetic processGO:000696310.451
amine metabolic processGO:0009308450.445
negative regulation of cell proliferationGO:00082852960.443
rhythmic processGO:00485111740.431
negative regulation of protein metabolic processGO:00512482820.430
ripoptosome assemblyGO:009734360.429
regulation of organ morphogenesisGO:20000271440.428
negative regulation of lymphocyte proliferationGO:0050672450.427
positive regulation of lymphocyte activationGO:00512511400.426
cellular ketone metabolic processGO:0042180840.424
regulation of defense response to virusGO:0050688180.424
Mouse
cell activation involved in immune responseGO:00022631260.421
regulation of cytoplasmic transportGO:19036491120.419
regulation of antibacterial peptide biosynthetic processGO:000280810.416
interleukin 12 biosynthetic processGO:004209080.415
negative regulation of response to woundingGO:1903035770.414
negative regulation of interleukin 13 secretionGO:200066610.413
lymphocyte mediated immunityGO:00024491390.413
Human
ossificationGO:00015032160.407
internal protein amino acid acetylationGO:0006475420.404
regulation of cholesterol effluxGO:0010874130.402
circadian regulation of gene expressionGO:0032922480.402
regulation of cytokine biosynthetic processGO:0042035590.402
cellular response to cytokine stimulusGO:00713451890.401
digestive system developmentGO:00551232000.397
regulation of protein catabolic processGO:00421761080.389
regulation of cellular ketone metabolic processGO:0010565660.389
positive regulation of lymphocyte proliferationGO:0050671700.387
negative regulation of b cell activationGO:0050869270.385
neural tube formationGO:00018411080.385
macromolecular complex disassemblyGO:0032984430.378
immunoglobulin secretionGO:0048305170.376
regulation of alpha beta t cell proliferationGO:0046640180.375
cellular amino acid metabolic processGO:00065201030.372
primary neural tube formationGO:0014020950.371
regulation of cellular protein catabolic processGO:1903362610.369
lymphocyte activation involved in immune responseGO:0002285930.367
response to organonitrogen compoundGO:00102432460.364
positive regulation of programmed cell deathGO:00430682180.361
nucleotide binding oligomerization domain containing 1 signaling pathwayGO:007042750.361
regulation of t cell mediated immunityGO:0002709340.356
Human
neuronal action potentialGO:0019228540.355
antibacterial peptide productionGO:000277820.354
regulation of t cell anergyGO:000266740.354
positive regulation of response to cytokine stimulusGO:0060760110.354
epithelial tube formationGO:00721751300.352
t cell anergyGO:000287040.351
regulation of intracellular transportGO:00323861590.349
response to organic cyclic compoundGO:00140701980.349
cytokine biosynthetic processGO:0042089680.348
negative regulation of interleukin 5 secretionGO:200066310.344
embryonic epithelial tube formationGO:00018381300.338
skin developmentGO:00435882200.337
positive regulation of cytokine production involved in immune responseGO:0002720190.334
Human
negative regulation of cell activationGO:00508661110.333
epithelial cell proliferationGO:00506731740.326
cd4 positive alpha beta t cell activationGO:0035710450.325
regulation of protein complex assemblyGO:0043254830.315
positive regulation of fever generation by positive regulation of prostaglandin secretionGO:007181220.314
t cell activation involved in immune responseGO:0002286430.311
regulation of lymphocyte anergyGO:000291140.308
modification dependent protein catabolic processGO:00199411330.307
positive regulation of protein localization to nucleusGO:1900182300.306
muscle cell proliferationGO:0033002520.305
Rat
defense response to other organismGO:00985421970.304
Mouse
positive regulation of lipopolysaccharide mediated signaling pathwayGO:003166650.303
negative regulation of interleukin 5 productionGO:003271440.298
response to peptideGO:19016521360.298
lymphocyte homeostasisGO:0002260640.297
protein k63 linked ubiquitinationGO:007053460.297
positive regulation of leukocyte proliferationGO:0070665730.296
hair follicle developmentGO:0001942850.294
regulation of bindingGO:00510981110.289
Human
odontogenesis of dentin containing toothGO:0042475660.289
activation of jnkk activityGO:000725630.289
leukocyte mediated immunityGO:00024431740.289
Human
circadian rhythmGO:00076231140.287
covalent chromatin modificationGO:00165691630.286
gland developmentGO:00487323300.286
regulation of cytokine secretion involved in immune responseGO:000273940.286
digestive tract morphogenesisGO:00485461470.285
regulation of antibacterial peptide productionGO:000278610.285
respiratory system developmentGO:00605411900.281
action potentialGO:0001508780.279
tube formationGO:00351481400.278
macrophage cytokine productionGO:001093490.278
negative regulation of odontogenesis of dentin containing toothGO:004248910.278
regulation of nucleocytoplasmic transportGO:0046822730.277
photoreceptor cell developmentGO:0042461400.274
positive regulation of cellular amino acid metabolic processGO:004576430.273
neural tube developmentGO:00219151600.272
chromatin organizationGO:00063252060.272
myeloid leukocyte cytokine productionGO:0061082120.271
negative regulation of odontogenesisGO:004248330.270
positive regulation of cytokine productionGO:00018191740.270
negative regulation of interleukin 13 productionGO:003269620.268
interferon beta productionGO:0032608160.265
Mouse
negative regulation of inflammatory responseGO:0050728610.265
regulation of reactive oxygen species metabolic processGO:2000377400.264
gastrulationGO:00073691160.260
alcohol metabolic processGO:00060661160.257
t cell differentiationGO:00302171740.257
regulation of cellular component biogenesisGO:00440871810.256
negative regulation of phosphate metabolic processGO:00459361840.251
transmission of nerve impulseGO:0019226760.251
protein complex disassemblyGO:0043241400.250
negative regulation of t cell proliferationGO:0042130380.248
regulation of response to biotic stimulusGO:0002831380.248
regulation of membrane potentialGO:00423911920.247
interleukin 2 productionGO:0032623330.246
Human
regulation of gliogenesisGO:0014013500.245
negative regulation of interleukin 12 productionGO:0032695100.245
negative regulation of alpha beta t cell activationGO:0046636180.245
protein modification by small protein removalGO:0070646210.244
lymphocyte anergyGO:000224940.243
purine nucleotide catabolic processGO:00061952110.242
positive regulation of t cell anergyGO:000266940.239
positive regulation of interleukin 2 productionGO:0032743190.239
Human
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781940.235
hepaticobiliary system developmentGO:0061008670.234
regulation of secretionGO:00510462740.233
cytokine production involved in inflammatory responseGO:000253490.229
regulation of protein localizationGO:00328802310.229
circadian temperature homeostasisGO:006008620.225
neuron apoptotic processGO:00514021420.224
positive regulation of antimicrobial humoral responseGO:000276020.224
regulation of macrophage cytokine productionGO:001093580.223
protein deubiquitinationGO:0016579190.221
positive regulation of leukocyte differentiationGO:1902107860.221
Human
positive regulation of hormone secretionGO:0046887380.221
response to interleukin 1GO:0070555110.218
wnt signaling pathwayGO:00160551880.218
dna metabolic processGO:00062593030.217
nitrogen compound transportGO:00717052710.212
negative regulation of tumor necrosis factor superfamily cytokine productionGO:1903556170.211
t cell mediated immunityGO:0002456500.206
Human
positive regulation of protein modification by small protein conjugation or removalGO:1903322300.206
regulation of response to cytokine stimulusGO:0060759230.202
b cell apoptotic processGO:0001783190.201
response to tumor necrosis factorGO:0034612260.200
Mouse
type i interferon productionGO:0032606290.199
Mouse
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.198
inflammatory responseGO:00069542440.198
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.197
negative regulation of macrophage cytokine productionGO:001093610.195
alpha beta t cell differentiationGO:0046632690.195
germinal center formationGO:0002467160.193
regulation of defense response to bacteriumGO:190042430.193
cytoplasmic transportGO:00164822340.192
cell type specific apoptotic processGO:00972852680.190
positive regulation of lymphocyte anergyGO:000291340.188
odontogenesisGO:0042476780.187
regulation of canonical wnt signaling pathwayGO:0060828820.187
regulation of lymphocyte proliferationGO:00506701170.187
synapse organizationGO:00508081250.187
negative regulation of cellular amine metabolic processGO:003323910.187
amide transportGO:00428861380.184
hormone secretionGO:00468791280.184
neural tube closureGO:0001843900.181
neuron deathGO:00709971540.180
regulation of cell migrationGO:00303342190.180
positive regulation of rac gtpase activityGO:0032855140.178
respiratory tube developmentGO:00303231670.177
Mouse
negative regulation of phosphorylationGO:00423261660.175
endodermal cell fate specificationGO:000171440.174
nuclear transportGO:00511691390.171
negative regulation of phosphorus metabolic processGO:00105631840.170
regulation of erk1 and erk2 cascadeGO:0070372710.167
protein localization to organelleGO:00333651850.162
peptidyl amino acid modificationGO:00181933360.161
positive regulation of peptide hormone secretionGO:0090277310.160
immunoglobulin mediated immune responseGO:0016064690.160
digestive tract developmentGO:00485651900.159
spleen developmentGO:0048536390.159
protein oligomerizationGO:0051259670.157
negative regulation of tumor necrosis factor productionGO:0032720170.157
positive regulation of cellular amine metabolic processGO:003324050.157
positive regulation of immature t cell proliferationGO:003309140.156
nucleotide binding oligomerization domain containing 2 signaling pathwayGO:007043160.156
positive regulation of intracellular transportGO:0032388700.155
rho protein signal transductionGO:0007266320.153
multicellular organismal signalingGO:0035637910.153
regulation of steroid biosynthetic processGO:0050810260.151
positive regulation of nucleocytoplasmic transportGO:0046824300.150
regulation of hepatocyte proliferationGO:200034560.148
regulation of protein transportGO:00512231630.146
t cell differentiation involved in immune responseGO:0002292300.146
i kappab phosphorylationGO:000725260.145
cellular response to organonitrogen compoundGO:00714171450.144
cytokine secretion involved in immune responseGO:000237460.144
autophagyGO:0006914450.141
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787250.140
homeostasis of number of cellsGO:00488722100.139
humoral immune responseGO:0006959570.139
negative regulation of t cell activationGO:0050868650.138
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316230.138
positive regulation of lymphocyte mediated immunityGO:0002708620.138
Human
regulation of inflammatory responseGO:00507271470.137
positive regulation of defense response to bacteriumGO:190042610.137
epithelial tube morphogenesisGO:00605623030.136
nucleocytoplasmic transportGO:00069131390.135
regulation of synaptic growth at neuromuscular junctionGO:000858240.134
regulation of protein localization to nucleusGO:1900180600.134
molting cycleGO:0042303900.133
regulation of cell cycleGO:00517262810.131
peptidyl serine phosphorylationGO:0018105740.130
establishment of protein localization to organelleGO:00725941180.130
skeletal system developmentGO:00015013560.129
regulation of cellular amino acid metabolic processGO:000652150.128
response to exogenous dsrnaGO:0043330220.127
positive regulation of peptide secretionGO:0002793330.127
immune response regulating cell surface receptor signaling pathwayGO:0002768800.127
Human
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.127
liver developmentGO:0001889660.126
myeloid leukocyte activationGO:0002274830.126
mesoderm developmentGO:00074981000.126
positive regulation of erk1 and erk2 cascadeGO:0070374470.125
antimicrobial peptide productionGO:000277520.124
peptidyl threonine phosphorylationGO:0018107310.123
regulation of interferon gamma productionGO:0032649570.122
b 1 b cell homeostasisGO:000192240.122
positive regulation of production of molecular mediator of immune responseGO:0002702450.122
Human
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.121
regulation of lymphocyte differentiationGO:00456191070.119
protein secretionGO:00093061110.118
regulation of organelle organizationGO:00330432890.118
regulation of response to woundingGO:19030341890.117
response to oxidative stressGO:00069791230.116
Mouse
negative regulation of cellular amino acid metabolic processGO:004576300.116
positive regulation of immune effector processGO:00026991070.116
Human
response to muramyl dipeptideGO:003249590.116
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630570.115
regulation of protein targetingGO:1903533610.115
regulation of ripoptosome assembly involved in necroptotic processGO:190244230.115
organic acid biosynthetic processGO:0016053860.114
regulation of cd8 positive alpha beta t cell extravasationGO:200044930.114
negative regulation of cellular protein metabolic processGO:00322692470.114
myelinationGO:0042552740.113
regulation of tight junction assemblyGO:200081020.111
regulation of cellular amine metabolic processGO:0033238200.111
regulation of antimicrobial humoral responseGO:000275930.109
positive regulation of cell activationGO:00508671580.109
negative regulation of lipid transportGO:003236980.109
mitochondrion organizationGO:00070051340.109
activation induced cell death of t cellsGO:0006924100.108
mesoderm formationGO:0001707620.108
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.107
antibacterial peptide biosynthetic processGO:000278020.107
proteasomal protein catabolic processGO:0010498980.107
mammary gland epithelium developmentGO:0061180650.106
organic hydroxy compound transportGO:0015850930.106
organic anion transportGO:00157111370.106
leukocyte activation involved in immune responseGO:00023661260.106
regulation of intracellular protein transportGO:0033157820.105
positive regulation of apoptotic signaling pathwayGO:2001235950.105
defense response to bacteriumGO:00427421190.104
organic hydroxy compound biosynthetic processGO:1901617770.104
positive regulation of intracellular protein transportGO:0090316420.104
protein import into nucleusGO:0006606950.103
regulation of glial cell differentiationGO:0045685410.103
tissue remodelingGO:00487711020.103
negative regulation of osteoblast differentiationGO:0045668300.102
lung developmentGO:00303241640.102
regulation of chromatin modificationGO:1903308570.101
bmp signaling pathwayGO:0030509930.100
cellular response to growth factor stimulusGO:00713631970.100
positive regulation of inflammatory responseGO:0050729470.099
negative regulation of protein complex disassemblyGO:0043242220.098
negative regulation of ossificationGO:0030279490.098
peptidyl threonine modificationGO:0018210310.098
compound eye developmentGO:004874910.097
regulation of peptidyl serine phosphorylationGO:0033135390.096
positive regulation of protein import into nucleusGO:0042307260.096
regulation of t cell differentiationGO:0045580830.096
positive regulation of antimicrobial peptide productionGO:000222510.096
positive regulation of cell deathGO:00109422240.095
peptidyl tyrosine phosphorylationGO:00181081430.095
regulation of immunoglobulin productionGO:0002637420.095
morphogenesis of embryonic epitheliumGO:00163311590.094
regulation of cellular catabolic processGO:00313292420.093
positive regulation of cytokine secretion involved in immune responseGO:000274120.093
regulation of leukocyte mediated immunityGO:00027031040.093
Human
leukocyte apoptotic processGO:0071887710.091
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071692470.091
positive regulation of cellular protein catabolic processGO:1903364340.091
mammary gland lobule developmentGO:0061377220.090
regulation of protein bindingGO:0043393600.090
positive regulation of leukocyte mediated immunityGO:0002705700.089
Human
regulation of protein ubiquitinationGO:0031396520.089
dendritic cell differentiationGO:0097028260.089
photoreceptor cell differentiationGO:0046530520.089
t cell cytokine productionGO:0002369100.089
Human
regulation of protein modification by small protein conjugation or removalGO:1903320570.089
osteoclast differentiationGO:0030316620.088
blood circulationGO:00080151950.088
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.088
negative regulation of leukocyte proliferationGO:0070664460.087
regulation of cellular response to growth factor stimulusGO:0090287820.087
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.086
trachea gland developmentGO:006115330.086
negative regulation of cytokine biosynthetic processGO:0042036130.086

Traf6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.366
musculoskeletal system diseaseDOID:1700.366
bone diseaseDOID:008000100.243
connective tissue diseaseDOID:6500.243
disease of cellular proliferationDOID:1456600.189
bone remodeling diseaseDOID:008000500.161
osteopetrosisDOID:1353300.161
osteosclerosisDOID:425400.161