| toll like receptor signaling pathway | GO:0002224 | 38 | 1.000 | Mouse |
| activation of nf kappab inducing kinase activity | GO:0007250 | 4 | 1.000 | Human |
| regulation of stress activated mapk cascade | GO:0032872 | 69 | 1.000 | Human Mouse |
| i kappab kinase nf kappab signaling | GO:0007249 | 85 | 1.000 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 106 | 1.000 | |
| activation of innate immune response | GO:0002218 | 56 | 1.000 | Mouse |
| nik nf kappab signaling | GO:0038061 | 14 | 1.000 | Human |
| ripoptosome assembly involved in necroptotic process | GO:1901026 | 6 | 1.000 | |
| regulation of jnk cascade | GO:0046328 | 62 | 0.999 | Human Mouse |
| positive regulation of innate immune response | GO:0045089 | 80 | 0.999 | Mouse |
| pattern recognition receptor signaling pathway | GO:0002221 | 47 | 0.999 | Mouse |
| jnk cascade | GO:0007254 | 72 | 0.999 | Human Mouse Rat |
| cytokine production involved in immune response | GO:0002367 | 34 | 0.999 | Human |
| lipopolysaccharide mediated signaling pathway | GO:0031663 | 25 | 0.999 | |
| activation of immune response | GO:0002253 | 138 | 0.999 | Human Mouse |
| negative regulation of nf kappab transcription factor activity | GO:0032088 | 15 | 0.999 | Mouse |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.999 | Human Mouse |
| stress activated protein kinase signaling cascade | GO:0031098 | 81 | 0.999 | Human Mouse Rat |
| innate immune response activating signal transduction | GO:0002758 | 50 | 0.998 | Mouse |
| positive regulation of jnk cascade | GO:0046330 | 46 | 0.998 | Human |
| regulation of innate immune response | GO:0045088 | 91 | 0.998 | Mouse |
| negative regulation of defense response | GO:0031348 | 77 | 0.998 | |
| regulation of cytokine production involved in immune response | GO:0002718 | 26 | 0.998 | Human |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.997 | Human |
| positive regulation of nf kappab transcription factor activity | GO:0051092 | 30 | 0.997 | |
| regulation of defense response | GO:0031347 | 233 | 0.996 | Mouse |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 68 | 0.995 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.993 | Human |
| positive regulation of jun kinase activity | GO:0043507 | 30 | 0.992 | Human |
| regulation of mapk cascade | GO:0043408 | 248 | 0.991 | Human Mouse |
| regulation of toll like receptor signaling pathway | GO:0034121 | 20 | 0.990 | |
| immune response regulating signaling pathway | GO:0002764 | 125 | 0.990 | Human Mouse |
| cellular response to lipopolysaccharide | GO:0071222 | 77 | 0.989 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.988 | Human |
| positive regulation of map kinase activity | GO:0043406 | 84 | 0.986 | Human |
| interleukin 13 secretion | GO:0072611 | 2 | 0.984 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.984 | Human |
| stress activated mapk cascade | GO:0051403 | 80 | 0.984 | Human Mouse Rat |
| toll like receptor 4 signaling pathway | GO:0034142 | 9 | 0.984 | |
| positive regulation of protein serine threonine kinase activity | GO:0071902 | 106 | 0.982 | Human |
| antigen receptor mediated signaling pathway | GO:0050851 | 64 | 0.980 | Human |
| immune response activating signal transduction | GO:0002757 | 116 | 0.978 | Human Mouse |
| regulation of interleukin 10 secretion | GO:2001179 | 4 | 0.978 | |
| mapk cascade | GO:0000165 | 281 | 0.978 | Human Mouse Rat |
| immune effector process | GO:0002252 | 321 | 0.975 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.975 | Human |
| lipid transport | GO:0006869 | 98 | 0.970 | |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.969 | Human |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 40 | 0.963 | Mouse |
| cytokine production | GO:0001816 | 319 | 0.963 | |
| negative regulation of immune system process | GO:0002683 | 209 | 0.963 | |
| response to lipopolysaccharide | GO:0032496 | 128 | 0.962 | |
| regulation of cytokine production | GO:0001817 | 266 | 0.960 | |
| regulation of map kinase activity | GO:0043405 | 120 | 0.960 | Human |
| cellular response to molecule of bacterial origin | GO:0071219 | 83 | 0.958 | |
| positive regulation of stress activated mapk cascade | GO:0032874 | 48 | 0.957 | Human |
| regulation of interleukin 6 production | GO:0032675 | 55 | 0.956 | |
| positive regulation of defense response | GO:0031349 | 124 | 0.954 | Mouse |
| interleukin 1 mediated signaling pathway | GO:0070498 | 4 | 0.951 | |
| negative regulation of innate immune response | GO:0045824 | 17 | 0.950 | |
| interleukin 5 secretion | GO:0072603 | 2 | 0.946 | |
| interleukin 6 production | GO:0032635 | 58 | 0.945 | |
| cholesterol transport | GO:0030301 | 38 | 0.943 | |
| cytokine mediated signaling pathway | GO:0019221 | 115 | 0.939 | |
| tolerance induction | GO:0002507 | 14 | 0.938 | |
| protein catabolic process | GO:0030163 | 221 | 0.937 | Mouse |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.935 | Human |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.931 | Human |
| positive regulation of tolerance induction | GO:0002645 | 8 | 0.929 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.927 | |
| negative regulation of toll like receptor signaling pathway | GO:0034122 | 14 | 0.926 | |
| negative regulation of ripoptosome assembly involved in necroptotic process | GO:1902443 | 3 | 0.923 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.921 | |
| cellular response to biotic stimulus | GO:0071216 | 92 | 0.921 | |
| cellular response to lipid | GO:0071396 | 145 | 0.918 | |
| protein autophosphorylation | GO:0046777 | 61 | 0.915 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.913 | Mouse |
| interleukin 12 production | GO:0032615 | 32 | 0.913 | |
| protein polyubiquitination | GO:0000209 | 33 | 0.909 | |
| regulation of tolerance induction | GO:0002643 | 10 | 0.902 | |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.891 | |
| regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002822 | 87 | 0.891 | Human |
| interleukin 10 secretion | GO:0072608 | 4 | 0.888 | |
| cytoplasmic pattern recognition receptor signaling pathway | GO:0002753 | 10 | 0.876 | |
| regulation of interleukin 12 production | GO:0032655 | 30 | 0.875 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.875 | |
| cholesterol efflux | GO:0033344 | 24 | 0.874 | |
| myeloid dendritic cell activation | GO:0001773 | 25 | 0.872 | |
| regulation of jun kinase activity | GO:0043506 | 40 | 0.871 | Human |
| myd88 independent toll like receptor signaling pathway | GO:0002756 | 3 | 0.870 | |
| negative regulation of kinase activity | GO:0033673 | 81 | 0.864 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.861 | Mouse |
| negative regulation of protein serine threonine kinase activity | GO:0071901 | 49 | 0.848 | |
| regulation of lipid transport | GO:0032368 | 36 | 0.835 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.835 | |
| negative regulation of immune effector process | GO:0002698 | 55 | 0.834 | |
| regulation of interleukin 2 production | GO:0032663 | 28 | 0.833 | Human |
| negative regulation of cytokine production | GO:0001818 | 84 | 0.832 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.831 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.828 | Human |
| negative regulation of sterol transport | GO:0032372 | 4 | 0.827 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.827 | Human |
| regulation of t cell activation | GO:0050863 | 170 | 0.818 | |
| tumor necrosis factor superfamily cytokine production | GO:0071706 | 51 | 0.813 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.809 | |
| regulation of lymphocyte activation | GO:0051249 | 240 | 0.807 | |
| regulation of interleukin 5 secretion | GO:2000662 | 2 | 0.801 | |
| negative regulation of map kinase activity | GO:0043407 | 34 | 0.799 | |
| regulation of interleukin 13 secretion | GO:2000665 | 2 | 0.792 | |
| negative regulation of interleukin 6 production | GO:0032715 | 17 | 0.790 | |
| regulation of nik nf kappab signaling | GO:1901222 | 10 | 0.790 | Human |
| regulation of cell activation | GO:0050865 | 289 | 0.788 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.786 | |
| negative regulation of protein phosphorylation | GO:0001933 | 126 | 0.781 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.779 | |
| t cell activation | GO:0042110 | 289 | 0.779 | |
| tumor necrosis factor production | GO:0032640 | 50 | 0.771 | |
| nucleotide binding oligomerization domain containing signaling pathway | GO:0070423 | 6 | 0.764 | |
| cellular response to interleukin 1 | GO:0071347 | 8 | 0.764 | |
| regulation of adaptive immune response | GO:0002819 | 90 | 0.756 | Human |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.742 | |
| lymphocyte differentiation | GO:0030098 | 242 | 0.738 | |
| response to dsrna | GO:0043331 | 30 | 0.737 | |
| protein ubiquitination | GO:0016567 | 171 | 0.732 | |
| histone modification | GO:0016570 | 159 | 0.727 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.721 | |
| positive regulation of nik nf kappab signaling | GO:1901224 | 7 | 0.721 | Human |
| t cell proliferation | GO:0042098 | 120 | 0.717 | |
| positive regulation of interleukin 12 production | GO:0032735 | 21 | 0.712 | |
| positive regulation of cytokine biosynthetic process | GO:0042108 | 40 | 0.712 | |
| regulation of leukocyte proliferation | GO:0070663 | 121 | 0.708 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.701 | |
| alpha beta t cell proliferation | GO:0046633 | 21 | 0.700 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.699 | |
| response to interleukin 12 | GO:0070671 | 2 | 0.688 | |
| response to growth factor | GO:0070848 | 198 | 0.688 | |
| regulation of t cell proliferation | GO:0042129 | 92 | 0.686 | |
| negative regulation of lymphocyte activation | GO:0051250 | 91 | 0.684 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.673 | |
| regulation of alpha beta t cell activation | GO:0046634 | 53 | 0.670 | |
| regulation of tumor necrosis factor production | GO:0032680 | 49 | 0.656 | |
| regulation of protein complex disassembly | GO:0043244 | 28 | 0.656 | |
| peptidyl serine modification | GO:0018209 | 83 | 0.652 | |
| tumor necrosis factor mediated signaling pathway | GO:0033209 | 13 | 0.646 | Mouse |
| t helper cell differentiation | GO:0042093 | 28 | 0.641 | |
| negative regulation of necroptotic process | GO:0060546 | 9 | 0.637 | |
| cd4 positive alpha beta t cell differentiation involved in immune response | GO:0002294 | 28 | 0.637 | |
| regulation of lymphocyte mediated immunity | GO:0002706 | 84 | 0.631 | Human |
| extrinsic apoptotic signaling pathway | GO:0097191 | 126 | 0.628 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.624 | |
| negative regulation of mapk cascade | GO:0043409 | 65 | 0.609 | |
| toll like receptor 2 signaling pathway | GO:0034134 | 6 | 0.607 | |
| negative regulation of interleukin 10 secretion | GO:2001180 | 2 | 0.607 | |
| necroptotic process | GO:0070266 | 21 | 0.604 | |
| regulation of sterol transport | GO:0032371 | 17 | 0.597 | |
| positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002824 | 61 | 0.595 | Human |
| negative regulation of transferase activity | GO:0051348 | 85 | 0.593 | |
| regulation of necroptotic process | GO:0060544 | 10 | 0.590 | |
| alpha beta t cell differentiation involved in immune response | GO:0002293 | 30 | 0.588 | |
| cellular response to tumor necrosis factor | GO:0071356 | 21 | 0.583 | Mouse |
| positive regulation of t cell cytokine production | GO:0002726 | 5 | 0.576 | Human |
| negative regulation of cytokine production involved in immune response | GO:0002719 | 5 | 0.574 | |
| regulation of leukocyte differentiation | GO:1902105 | 159 | 0.571 | Human |
| lipid localization | GO:0010876 | 126 | 0.568 | |
| leukocyte proliferation | GO:0070661 | 172 | 0.567 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.566 | |
| regulation of production of molecular mediator of immune response | GO:0002700 | 65 | 0.559 | |
| innate immune response | GO:0045087 | 157 | 0.555 | Zebrafish Mouse |
| glial cell apoptotic process | GO:0034349 | 3 | 0.552 | |
| regulation of tumor necrosis factor superfamily cytokine production | GO:1903555 | 50 | 0.550 | |
| necrotic cell death | GO:0070265 | 30 | 0.545 | Mouse |
| sterol transport | GO:0015918 | 38 | 0.543 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.541 | |
| production of molecular mediator of immune response | GO:0002440 | 103 | 0.541 | |
| alpha beta t cell activation | GO:0046631 | 91 | 0.537 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.524 | |
| negative regulation of protein catabolic process | GO:0042177 | 36 | 0.524 | |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | GO:0002460 | 145 | 0.518 | |
| leukocyte differentiation | GO:0002521 | 342 | 0.509 | |
| response to peptidoglycan | GO:0032494 | 9 | 0.504 | |
| regulation of cholesterol transport | GO:0032374 | 17 | 0.501 | |
| cd4 positive alpha beta t cell differentiation | GO:0043367 | 41 | 0.493 | |
| negative regulation of necrotic cell death | GO:0060547 | 11 | 0.493 | |
| myeloid dendritic cell differentiation | GO:0043011 | 16 | 0.486 | |
| positive regulation of t cell mediated immunity | GO:0002711 | 24 | 0.477 | Human |
| lymphocyte apoptotic process | GO:0070227 | 54 | 0.466 | |
| adaptive immune response | GO:0002250 | 155 | 0.456 | |
| negative regulation of cholesterol transport | GO:0032375 | 4 | 0.453 | |
| positive regulation of antibacterial peptide biosynthetic process | GO:0006963 | 1 | 0.451 | |
| amine metabolic process | GO:0009308 | 45 | 0.445 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.443 | |
| rhythmic process | GO:0048511 | 174 | 0.431 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.430 | |
| ripoptosome assembly | GO:0097343 | 6 | 0.429 | |
| regulation of organ morphogenesis | GO:2000027 | 144 | 0.428 | |
| negative regulation of lymphocyte proliferation | GO:0050672 | 45 | 0.427 | |
| positive regulation of lymphocyte activation | GO:0051251 | 140 | 0.426 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.424 | |
| regulation of defense response to virus | GO:0050688 | 18 | 0.424 | Mouse |
| cell activation involved in immune response | GO:0002263 | 126 | 0.421 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.419 | |
| regulation of antibacterial peptide biosynthetic process | GO:0002808 | 1 | 0.416 | |
| interleukin 12 biosynthetic process | GO:0042090 | 8 | 0.415 | |
| negative regulation of response to wounding | GO:1903035 | 77 | 0.414 | |
| negative regulation of interleukin 13 secretion | GO:2000666 | 1 | 0.413 | |
| lymphocyte mediated immunity | GO:0002449 | 139 | 0.413 | Human |
| ossification | GO:0001503 | 216 | 0.407 | |
| internal protein amino acid acetylation | GO:0006475 | 42 | 0.404 | |
| regulation of cholesterol efflux | GO:0010874 | 13 | 0.402 | |
| circadian regulation of gene expression | GO:0032922 | 48 | 0.402 | |
| regulation of cytokine biosynthetic process | GO:0042035 | 59 | 0.402 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.401 | |
| digestive system development | GO:0055123 | 200 | 0.397 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.389 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.389 | |
| positive regulation of lymphocyte proliferation | GO:0050671 | 70 | 0.387 | |
| negative regulation of b cell activation | GO:0050869 | 27 | 0.385 | |
| neural tube formation | GO:0001841 | 108 | 0.385 | |
| macromolecular complex disassembly | GO:0032984 | 43 | 0.378 | |
| immunoglobulin secretion | GO:0048305 | 17 | 0.376 | |
| regulation of alpha beta t cell proliferation | GO:0046640 | 18 | 0.375 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.372 | |
| primary neural tube formation | GO:0014020 | 95 | 0.371 | |
| regulation of cellular protein catabolic process | GO:1903362 | 61 | 0.369 | |
| lymphocyte activation involved in immune response | GO:0002285 | 93 | 0.367 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.364 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.361 | |
| nucleotide binding oligomerization domain containing 1 signaling pathway | GO:0070427 | 5 | 0.361 | |
| regulation of t cell mediated immunity | GO:0002709 | 34 | 0.356 | Human |
| neuronal action potential | GO:0019228 | 54 | 0.355 | |
| antibacterial peptide production | GO:0002778 | 2 | 0.354 | |
| regulation of t cell anergy | GO:0002667 | 4 | 0.354 | |
| positive regulation of response to cytokine stimulus | GO:0060760 | 11 | 0.354 | |
| epithelial tube formation | GO:0072175 | 130 | 0.352 | |
| t cell anergy | GO:0002870 | 4 | 0.351 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.349 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.349 | |
| cytokine biosynthetic process | GO:0042089 | 68 | 0.348 | |
| negative regulation of interleukin 5 secretion | GO:2000663 | 1 | 0.344 | |
| embryonic epithelial tube formation | GO:0001838 | 130 | 0.338 | |
| skin development | GO:0043588 | 220 | 0.337 | |
| positive regulation of cytokine production involved in immune response | GO:0002720 | 19 | 0.334 | Human |
| negative regulation of cell activation | GO:0050866 | 111 | 0.333 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.326 | |
| cd4 positive alpha beta t cell activation | GO:0035710 | 45 | 0.325 | |
| regulation of protein complex assembly | GO:0043254 | 83 | 0.315 | |
| positive regulation of fever generation by positive regulation of prostaglandin secretion | GO:0071812 | 2 | 0.314 | |
| t cell activation involved in immune response | GO:0002286 | 43 | 0.311 | |
| regulation of lymphocyte anergy | GO:0002911 | 4 | 0.308 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.307 | |
| positive regulation of protein localization to nucleus | GO:1900182 | 30 | 0.306 | |
| muscle cell proliferation | GO:0033002 | 52 | 0.305 | Rat |
| defense response to other organism | GO:0098542 | 197 | 0.304 | Mouse |
| positive regulation of lipopolysaccharide mediated signaling pathway | GO:0031666 | 5 | 0.303 | |
| negative regulation of interleukin 5 production | GO:0032714 | 4 | 0.298 | |
| response to peptide | GO:1901652 | 136 | 0.298 | |
| lymphocyte homeostasis | GO:0002260 | 64 | 0.297 | |
| protein k63 linked ubiquitination | GO:0070534 | 6 | 0.297 | |
| positive regulation of leukocyte proliferation | GO:0070665 | 73 | 0.296 | |
| hair follicle development | GO:0001942 | 85 | 0.294 | |
| regulation of binding | GO:0051098 | 111 | 0.289 | Human |
| odontogenesis of dentin containing tooth | GO:0042475 | 66 | 0.289 | |
| activation of jnkk activity | GO:0007256 | 3 | 0.289 | |
| leukocyte mediated immunity | GO:0002443 | 174 | 0.289 | Human |
| circadian rhythm | GO:0007623 | 114 | 0.287 | |
| covalent chromatin modification | GO:0016569 | 163 | 0.286 | |
| gland development | GO:0048732 | 330 | 0.286 | |
| regulation of cytokine secretion involved in immune response | GO:0002739 | 4 | 0.286 | |
| digestive tract morphogenesis | GO:0048546 | 147 | 0.285 | |
| regulation of antibacterial peptide production | GO:0002786 | 1 | 0.285 | |
| respiratory system development | GO:0060541 | 190 | 0.281 | |
| action potential | GO:0001508 | 78 | 0.279 | |
| tube formation | GO:0035148 | 140 | 0.278 | |
| macrophage cytokine production | GO:0010934 | 9 | 0.278 | |
| negative regulation of odontogenesis of dentin containing tooth | GO:0042489 | 1 | 0.278 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 73 | 0.277 | |
| photoreceptor cell development | GO:0042461 | 40 | 0.274 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.273 | |
| neural tube development | GO:0021915 | 160 | 0.272 | |
| chromatin organization | GO:0006325 | 206 | 0.272 | |
| myeloid leukocyte cytokine production | GO:0061082 | 12 | 0.271 | |
| negative regulation of odontogenesis | GO:0042483 | 3 | 0.270 | |
| positive regulation of cytokine production | GO:0001819 | 174 | 0.270 | |
| negative regulation of interleukin 13 production | GO:0032696 | 2 | 0.268 | |
| interferon beta production | GO:0032608 | 16 | 0.265 | Mouse |
| negative regulation of inflammatory response | GO:0050728 | 61 | 0.265 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 40 | 0.264 | |
| gastrulation | GO:0007369 | 116 | 0.260 | |
| alcohol metabolic process | GO:0006066 | 116 | 0.257 | |
| t cell differentiation | GO:0030217 | 174 | 0.257 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.256 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.251 | |
| transmission of nerve impulse | GO:0019226 | 76 | 0.251 | |
| protein complex disassembly | GO:0043241 | 40 | 0.250 | |
| negative regulation of t cell proliferation | GO:0042130 | 38 | 0.248 | |
| regulation of response to biotic stimulus | GO:0002831 | 38 | 0.248 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.247 | |
| interleukin 2 production | GO:0032623 | 33 | 0.246 | Human |
| regulation of gliogenesis | GO:0014013 | 50 | 0.245 | |
| negative regulation of interleukin 12 production | GO:0032695 | 10 | 0.245 | |
| negative regulation of alpha beta t cell activation | GO:0046636 | 18 | 0.245 | |
| protein modification by small protein removal | GO:0070646 | 21 | 0.244 | |
| lymphocyte anergy | GO:0002249 | 4 | 0.243 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.242 | |
| positive regulation of t cell anergy | GO:0002669 | 4 | 0.239 | |
| positive regulation of interleukin 2 production | GO:0032743 | 19 | 0.239 | Human |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 194 | 0.235 | |
| hepaticobiliary system development | GO:0061008 | 67 | 0.234 | |
| regulation of secretion | GO:0051046 | 274 | 0.233 | |
| cytokine production involved in inflammatory response | GO:0002534 | 9 | 0.229 | |
| regulation of protein localization | GO:0032880 | 231 | 0.229 | |
| circadian temperature homeostasis | GO:0060086 | 2 | 0.225 | |
| neuron apoptotic process | GO:0051402 | 142 | 0.224 | |
| positive regulation of antimicrobial humoral response | GO:0002760 | 2 | 0.224 | |
| regulation of macrophage cytokine production | GO:0010935 | 8 | 0.223 | |
| protein deubiquitination | GO:0016579 | 19 | 0.221 | |
| positive regulation of leukocyte differentiation | GO:1902107 | 86 | 0.221 | Human |
| positive regulation of hormone secretion | GO:0046887 | 38 | 0.221 | |
| response to interleukin 1 | GO:0070555 | 11 | 0.218 | |
| wnt signaling pathway | GO:0016055 | 188 | 0.218 | |
| dna metabolic process | GO:0006259 | 303 | 0.217 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.212 | |
| negative regulation of tumor necrosis factor superfamily cytokine production | GO:1903556 | 17 | 0.211 | |
| t cell mediated immunity | GO:0002456 | 50 | 0.206 | Human |
| positive regulation of protein modification by small protein conjugation or removal | GO:1903322 | 30 | 0.206 | |
| regulation of response to cytokine stimulus | GO:0060759 | 23 | 0.202 | |
| b cell apoptotic process | GO:0001783 | 19 | 0.201 | |
| response to tumor necrosis factor | GO:0034612 | 26 | 0.200 | Mouse |
| type i interferon production | GO:0032606 | 29 | 0.199 | Mouse |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 77 | 0.198 | |
| inflammatory response | GO:0006954 | 244 | 0.198 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.197 | |
| negative regulation of macrophage cytokine production | GO:0010936 | 1 | 0.195 | |
| alpha beta t cell differentiation | GO:0046632 | 69 | 0.195 | |
| germinal center formation | GO:0002467 | 16 | 0.193 | |
| regulation of defense response to bacterium | GO:1900424 | 3 | 0.193 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.192 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.190 | |
| positive regulation of lymphocyte anergy | GO:0002913 | 4 | 0.188 | |
| odontogenesis | GO:0042476 | 78 | 0.187 | |
| regulation of canonical wnt signaling pathway | GO:0060828 | 82 | 0.187 | |
| regulation of lymphocyte proliferation | GO:0050670 | 117 | 0.187 | |
| synapse organization | GO:0050808 | 125 | 0.187 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.187 | |
| amide transport | GO:0042886 | 138 | 0.184 | |
| hormone secretion | GO:0046879 | 128 | 0.184 | |
| neural tube closure | GO:0001843 | 90 | 0.181 | |
| neuron death | GO:0070997 | 154 | 0.180 | |
| regulation of cell migration | GO:0030334 | 219 | 0.180 | |
| positive regulation of rac gtpase activity | GO:0032855 | 14 | 0.178 | |
| respiratory tube development | GO:0030323 | 167 | 0.177 | Mouse |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.175 | |
| endodermal cell fate specification | GO:0001714 | 4 | 0.174 | |
| nuclear transport | GO:0051169 | 139 | 0.171 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.170 | |
| regulation of erk1 and erk2 cascade | GO:0070372 | 71 | 0.167 | |
| protein localization to organelle | GO:0033365 | 185 | 0.162 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.161 | |
| positive regulation of peptide hormone secretion | GO:0090277 | 31 | 0.160 | |
| immunoglobulin mediated immune response | GO:0016064 | 69 | 0.160 | |
| digestive tract development | GO:0048565 | 190 | 0.159 | |
| spleen development | GO:0048536 | 39 | 0.159 | |
| protein oligomerization | GO:0051259 | 67 | 0.157 | |
| negative regulation of tumor necrosis factor production | GO:0032720 | 17 | 0.157 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.157 | |
| positive regulation of immature t cell proliferation | GO:0033091 | 4 | 0.156 | |
| nucleotide binding oligomerization domain containing 2 signaling pathway | GO:0070431 | 6 | 0.156 | |
| positive regulation of intracellular transport | GO:0032388 | 70 | 0.155 | |
| rho protein signal transduction | GO:0007266 | 32 | 0.153 | |
| multicellular organismal signaling | GO:0035637 | 91 | 0.153 | |
| regulation of steroid biosynthetic process | GO:0050810 | 26 | 0.151 | |
| positive regulation of nucleocytoplasmic transport | GO:0046824 | 30 | 0.150 | |
| regulation of hepatocyte proliferation | GO:2000345 | 6 | 0.148 | |
| regulation of protein transport | GO:0051223 | 163 | 0.146 | |
| t cell differentiation involved in immune response | GO:0002292 | 30 | 0.146 | |
| i kappab phosphorylation | GO:0007252 | 6 | 0.145 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.144 | |
| cytokine secretion involved in immune response | GO:0002374 | 6 | 0.144 | |
| autophagy | GO:0006914 | 45 | 0.141 | |
| protein ubiquitination involved in ubiquitin dependent protein catabolic process | GO:0042787 | 25 | 0.140 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.139 | |
| humoral immune response | GO:0006959 | 57 | 0.139 | |
| negative regulation of t cell activation | GO:0050868 | 65 | 0.138 | |
| ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway | GO:0043162 | 3 | 0.138 | |
| positive regulation of lymphocyte mediated immunity | GO:0002708 | 62 | 0.138 | Human |
| regulation of inflammatory response | GO:0050727 | 147 | 0.137 | |
| positive regulation of defense response to bacterium | GO:1900426 | 1 | 0.137 | |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.136 | |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.135 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.134 | |
| regulation of protein localization to nucleus | GO:1900180 | 60 | 0.134 | |
| molting cycle | GO:0042303 | 90 | 0.133 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.131 | |
| peptidyl serine phosphorylation | GO:0018105 | 74 | 0.130 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.130 | |
| skeletal system development | GO:0001501 | 356 | 0.129 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.128 | |
| response to exogenous dsrna | GO:0043330 | 22 | 0.127 | |
| positive regulation of peptide secretion | GO:0002793 | 33 | 0.127 | |
| immune response regulating cell surface receptor signaling pathway | GO:0002768 | 80 | 0.127 | Human |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 61 | 0.127 | |
| liver development | GO:0001889 | 66 | 0.126 | |
| myeloid leukocyte activation | GO:0002274 | 83 | 0.126 | |
| mesoderm development | GO:0007498 | 100 | 0.126 | |
| positive regulation of erk1 and erk2 cascade | GO:0070374 | 47 | 0.125 | |
| antimicrobial peptide production | GO:0002775 | 2 | 0.124 | |
| peptidyl threonine phosphorylation | GO:0018107 | 31 | 0.123 | |
| regulation of interferon gamma production | GO:0032649 | 57 | 0.122 | |
| b 1 b cell homeostasis | GO:0001922 | 4 | 0.122 | |
| positive regulation of production of molecular mediator of immune response | GO:0002702 | 45 | 0.122 | Human |
| negative regulation of extrinsic apoptotic signaling pathway | GO:2001237 | 45 | 0.121 | |
| regulation of lymphocyte differentiation | GO:0045619 | 107 | 0.119 | |
| protein secretion | GO:0009306 | 111 | 0.118 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.118 | |
| regulation of response to wounding | GO:1903034 | 189 | 0.117 | |
| response to oxidative stress | GO:0006979 | 123 | 0.116 | Mouse |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.116 | |
| positive regulation of immune effector process | GO:0002699 | 107 | 0.116 | Human |
| response to muramyl dipeptide | GO:0032495 | 9 | 0.116 | |
| intrinsic apoptotic signaling pathway in response to dna damage | GO:0008630 | 57 | 0.115 | |
| regulation of protein targeting | GO:1903533 | 61 | 0.115 | |
| regulation of ripoptosome assembly involved in necroptotic process | GO:1902442 | 3 | 0.115 | |
| organic acid biosynthetic process | GO:0016053 | 86 | 0.114 | |
| regulation of cd8 positive alpha beta t cell extravasation | GO:2000449 | 3 | 0.114 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.114 | |
| myelination | GO:0042552 | 74 | 0.113 | |
| regulation of tight junction assembly | GO:2000810 | 2 | 0.111 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.111 | |
| regulation of antimicrobial humoral response | GO:0002759 | 3 | 0.109 | |
| positive regulation of cell activation | GO:0050867 | 158 | 0.109 | |
| negative regulation of lipid transport | GO:0032369 | 8 | 0.109 | |
| mitochondrion organization | GO:0007005 | 134 | 0.109 | |
| activation induced cell death of t cells | GO:0006924 | 10 | 0.108 | |
| mesoderm formation | GO:0001707 | 62 | 0.108 | |
| extrinsic apoptotic signaling pathway in absence of ligand | GO:0097192 | 55 | 0.107 | |
| antibacterial peptide biosynthetic process | GO:0002780 | 2 | 0.107 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.107 | |
| mammary gland epithelium development | GO:0061180 | 65 | 0.106 | |
| organic hydroxy compound transport | GO:0015850 | 93 | 0.106 | |
| organic anion transport | GO:0015711 | 137 | 0.106 | |
| leukocyte activation involved in immune response | GO:0002366 | 126 | 0.106 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.105 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 95 | 0.105 | |
| defense response to bacterium | GO:0042742 | 119 | 0.104 | |
| organic hydroxy compound biosynthetic process | GO:1901617 | 77 | 0.104 | |
| positive regulation of intracellular protein transport | GO:0090316 | 42 | 0.104 | |
| protein import into nucleus | GO:0006606 | 95 | 0.103 | |
| regulation of glial cell differentiation | GO:0045685 | 41 | 0.103 | |
| tissue remodeling | GO:0048771 | 102 | 0.103 | |
| negative regulation of osteoblast differentiation | GO:0045668 | 30 | 0.102 | |
| lung development | GO:0030324 | 164 | 0.102 | |
| regulation of chromatin modification | GO:1903308 | 57 | 0.101 | |
| bmp signaling pathway | GO:0030509 | 93 | 0.100 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.100 | |
| positive regulation of inflammatory response | GO:0050729 | 47 | 0.099 | |
| negative regulation of protein complex disassembly | GO:0043242 | 22 | 0.098 | |
| negative regulation of ossification | GO:0030279 | 49 | 0.098 | |
| peptidyl threonine modification | GO:0018210 | 31 | 0.098 | |
| compound eye development | GO:0048749 | 1 | 0.097 | |
| regulation of peptidyl serine phosphorylation | GO:0033135 | 39 | 0.096 | |
| positive regulation of protein import into nucleus | GO:0042307 | 26 | 0.096 | |
| regulation of t cell differentiation | GO:0045580 | 83 | 0.096 | |
| positive regulation of antimicrobial peptide production | GO:0002225 | 1 | 0.096 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.095 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 143 | 0.095 | |
| regulation of immunoglobulin production | GO:0002637 | 42 | 0.095 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 159 | 0.094 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.093 | |
| positive regulation of cytokine secretion involved in immune response | GO:0002741 | 2 | 0.093 | |
| regulation of leukocyte mediated immunity | GO:0002703 | 104 | 0.093 | Human |
| leukocyte apoptotic process | GO:0071887 | 71 | 0.091 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.091 | |
| positive regulation of cellular protein catabolic process | GO:1903364 | 34 | 0.091 | |
| mammary gland lobule development | GO:0061377 | 22 | 0.090 | |
| regulation of protein binding | GO:0043393 | 60 | 0.090 | |
| positive regulation of leukocyte mediated immunity | GO:0002705 | 70 | 0.089 | Human |
| regulation of protein ubiquitination | GO:0031396 | 52 | 0.089 | |
| dendritic cell differentiation | GO:0097028 | 26 | 0.089 | |
| photoreceptor cell differentiation | GO:0046530 | 52 | 0.089 | |
| t cell cytokine production | GO:0002369 | 10 | 0.089 | Human |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 57 | 0.089 | |
| osteoclast differentiation | GO:0030316 | 62 | 0.088 | |
| blood circulation | GO:0008015 | 195 | 0.088 | |
| extrinsic apoptotic signaling pathway via death domain receptors | GO:0008625 | 34 | 0.088 | |
| negative regulation of leukocyte proliferation | GO:0070664 | 46 | 0.087 | |
| regulation of cellular response to growth factor stimulus | GO:0090287 | 82 | 0.087 | |
| positive regulation of extrinsic apoptotic signaling pathway | GO:2001238 | 34 | 0.086 | |
| trachea gland development | GO:0061153 | 3 | 0.086 | |
| negative regulation of cytokine biosynthetic process | GO:0042036 | 13 | 0.086 | |
