Mus musculus

123 known processes

Vhl

von Hippel-Lindau tumor suppressor

(Aliases: Vhlh)

Vhl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
release of cytochrome c from mitochondriaGO:0001836230.999
positive regulation of apoptotic process involved in mammary gland involutionGO:006005840.991
regulation of dna templated transcription in response to stressGO:004362090.988
Human
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361880.975
Human
urogenital system developmentGO:00016552610.970
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:009729620.963
gas homeostasisGO:003348330.949
glial cell apoptotic processGO:003434930.946
peptidyl amino acid modificationGO:00181933360.945
hypoxia inducible factor 1alpha signaling pathwayGO:009741120.928
mesonephric tubule developmentGO:0072164940.920
cellular macromolecule catabolic processGO:00442652060.913
mitochondrion organizationGO:00070051340.905
regulation of cellular ketone metabolic processGO:0010565660.896
response to peptide hormoneGO:00434341270.876
positive regulation of apoptotic signaling pathwayGO:2001235950.869
proteasomal protein catabolic processGO:0010498980.868
erythrocyte differentiationGO:0030218880.866
Zebrafish
kidney developmentGO:00018222130.865
positive regulation of glial cell proliferationGO:006025240.861
positive regulation of apoptotic process involved in morphogenesisGO:190233940.853
establishment or maintenance of cytoskeleton polarityGO:003095220.850
negative regulation of cell proliferationGO:00082852960.843
negative regulation of cellular amine metabolic processGO:003323910.840
negative regulation of release of cytochrome c from mitochondriaGO:009020160.837
cellular response to insulin stimulusGO:0032869780.836
activation of cysteine type endopeptidase activityGO:0097202270.833
purine containing compound metabolic processGO:00725213110.827
purine nucleotide metabolic processGO:00061633020.822
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625340.818
regulation of neuron deathGO:19012141340.807
embryonic placenta developmentGO:0001892980.801
establishment or maintenance of microtubule cytoskeleton polarityGO:003095110.798
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:200126930.784
negative regulation of cellular amino acid metabolic processGO:004576300.781
homeostasis of number of cellsGO:00488722100.762
Zebrafish
action potentialGO:0001508780.761
b 1 b cell homeostasisGO:000192240.760
negative regulation of peptidyl tyrosine phosphorylationGO:0050732170.759
cell type specific apoptotic processGO:00972852680.757
neuronal action potentialGO:0019228540.753
protein processingGO:00164851630.751
blood coagulationGO:0007596760.750
apoptotic signaling pathwayGO:00971903060.745
inflammatory responseGO:00069542440.741
ribonucleotide metabolic processGO:00092592910.727
cellular response to decreased oxygen levelsGO:0036294180.727
Human Fly
ameboidal type cell migrationGO:00016671280.724
negative regulation of protein phosphorylationGO:00019331260.720
regulation of protein targetingGO:1903533610.719
muscle tissue developmentGO:00605373080.717
nucleoside phosphate metabolic processGO:00067533380.715
metanephric glomerular mesangium developmentGO:007222330.710
apoptotic process involved in mammary gland involutionGO:006005740.709
proteolysis involved in cellular protein catabolic processGO:00516031470.709
hemostasisGO:0007599780.707
negative regulation of lymphocyte apoptotic processGO:0070229240.701
negative regulation of anoikisGO:200081120.700
apoptotic mitochondrial changesGO:0008637480.699
maternal process involved in female pregnancyGO:0060135320.699
positive regulation of nervous system developmentGO:00519622210.693
endothelial cell apoptotic processGO:007257790.690
response to corticosteroneGO:005141210.680
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:200126740.679
thymocyte apoptotic processGO:0070242190.669
muscle cell differentiationGO:00426922610.658
digestive tract morphogenesisGO:00485461470.655
germ cell developmentGO:00072811850.653
cytoplasmic transportGO:00164822340.649
inflammatory response to woundingGO:009059440.649
blood vessel morphogenesisGO:00485142850.648
regulation of ral gtpase activityGO:003231540.646
positive regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902110110.646
regulation of neuron apoptotic processGO:00435231220.641
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332350.641
regulation of cellular catabolic processGO:00313292420.639
negative regulation of apoptotic signaling pathwayGO:20012341040.638
placenta developmentGO:00018901400.634
lymphocyte homeostasisGO:0002260640.624
regulation of membrane potentialGO:00423911920.622
regulation of purine nucleotide metabolic processGO:19005421690.617
regulation of mitochondrion organizationGO:0010821270.614
regulation of hemostasisGO:1900046280.613
protein catabolic processGO:00301632210.611
autophagyGO:0006914450.607
positive regulation of apoptotic processGO:00430652170.600
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281620.600
lactationGO:0007595250.599
connective tissue replacement involved in inflammatory response wound healingGO:000224830.593
purine ribonucleotide metabolic processGO:00091502900.592
glycoprotein metabolic processGO:00091001160.579
formation of radial glial scaffoldsGO:002194340.578
t cell activationGO:00421102890.578
single organism cell adhesionGO:00986021560.576
regulation of nucleotide metabolic processGO:00061401690.575
response to radiationGO:00093141650.572
cellular amine metabolic processGO:0044106440.570
neuron apoptotic processGO:00514021420.564
ribose phosphate metabolic processGO:00196932910.556
transmission of nerve impulseGO:0019226760.552
positive regulation of t helper 2 cell cytokine productionGO:200055330.551
amine metabolic processGO:0009308450.551
response to insulinGO:00328681000.550
cellular amino acid metabolic processGO:00065201030.550
cellular response to gamma radiationGO:007148040.548
positive regulation of leukocyte proliferationGO:0070665730.547
glycogen cell differentiation involved in embryonic placenta developmentGO:006070910.546
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631190.545
regulation of release of cytochrome c from mitochondriaGO:0090199110.541
intracellular protein transportGO:00068862040.539
extrinsic apoptotic signaling pathwayGO:00971911260.537
cell growthGO:00160491300.537
cellular response to peptideGO:1901653920.536
regulation of apoptotic signaling pathwayGO:20012331970.536
neuroblast proliferationGO:0007405490.535
myelination in peripheral nervous systemGO:0022011190.535
kidney epithelium developmentGO:00720731210.532
carbohydrate homeostasisGO:00335001280.522
cellular response to light stimulusGO:0071482190.521
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079160.520
regulation of endothelial cell chemotaxisGO:200102610.518
regulation of cellular amine metabolic processGO:0033238200.513
cellular response to hormone stimulusGO:00328701500.512
regulation of cellular amino acid metabolic processGO:000652150.511
regulation of protein localizationGO:00328802310.509
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902043130.504
myeloid cell homeostasisGO:00022621140.498
Zebrafish
microtubule cytoskeleton organizationGO:00002261570.497
Fly
neural tube developmentGO:00219151600.494
actin filament organizationGO:00070151130.494
connective tissue developmentGO:00614481790.492
regulation of erythrocyte differentiationGO:0045646230.491
oxygen homeostasisGO:003236420.489
positive regulation of b cell apoptotic processGO:000290440.489
positive regulation of mammary gland involutionGO:190352140.487
cellular response to dna damage stimulusGO:00069742070.485
establishment or maintenance of cell polarityGO:0007163860.484
Fly
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217640.482
mitotic cell cycleGO:00002781950.477
Fly
positive regulation of protein modification processGO:00314012990.476
t cell apoptotic processGO:0070231390.472
cellular response to oxidative stressGO:0034599760.470
negative regulation of tor signalingGO:0032007130.469
regulation of blood coagulationGO:0030193280.468
cellular response to radiationGO:0071478280.467
regulation of proteasomal protein catabolic processGO:0061136460.465
negative regulation of cell cycleGO:00457861230.465
negative regulation of phosphate metabolic processGO:00459361840.464
positive regulation of proteolysisGO:0045862850.464
substrate dependent cell migration cell extensionGO:000693040.464
positive regulation of cell proliferation involved in heart valve morphogenesisGO:000325110.463
nucleotide metabolic processGO:00091173320.462
negative regulation of cellular protein metabolic processGO:00322692470.457
axon transport of mitochondrionGO:001989620.456
mesonephric epithelium developmentGO:0072163940.454
regulation of fibroblast proliferationGO:0048145340.450
glucose import in response to insulin stimulusGO:004438180.450
protein modification by small protein conjugationGO:00324461870.449
Human Fly
negative regulation of neuron apoptotic processGO:0043524920.448
response to granulocyte macrophage colony stimulating factorGO:009701230.447
positive regulation of interleukin 5 secretionGO:200066410.447
regulation of insulin receptor signaling pathwayGO:0046626210.446
response to growth factorGO:00708481980.445
Zebrafish
cellular response to growth factor stimulusGO:00713631970.439
Zebrafish
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243340.439
hindbrain radial glia guided cell migrationGO:0021932120.439
response to light stimulusGO:00094161350.436
wound healing involved in inflammatory responseGO:000224640.433
positive regulation of programmed cell deathGO:00430682180.432
regulation of wound healingGO:0061041400.431
negative regulation of protein metabolic processGO:00512482820.422
modification dependent protein catabolic processGO:00199411330.422
regulation of response to oxidative stressGO:1902882190.420
signal transduction by p53 class mediatorGO:0072331510.419
skeletal muscle organ developmentGO:00605381630.419
protein export from nucleusGO:0006611200.418
Fly
regulation of angiogenesisGO:0045765810.414
Zebrafish
regulation of peptidase activityGO:0052547960.413
regulation of cellular protein catabolic processGO:1903362610.412
regulation of hydrolase activityGO:00513362460.408
mammary gland involutionGO:006005690.405
organelle fusionGO:0048284280.404
response to nitric oxideGO:007173140.404
zymogen activationGO:0031638410.400
organonitrogen compound catabolic processGO:19015652640.400
positive regulation of smooth muscle cell migrationGO:001491140.398
neural precursor cell proliferationGO:00613511210.398
regulation of cell activationGO:00508652890.396
cellular ketone metabolic processGO:0042180840.396
neuron projection extensionGO:1990138640.394
regulation of cell cycleGO:00517262810.394
purine ribonucleoside triphosphate metabolic processGO:00092052200.393
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathwayGO:190337630.391
regulation of body fluid levelsGO:00508781620.391
cellular component assembly involved in morphogenesisGO:00109271390.390
protein maturationGO:00516041760.390
cell adhesionGO:00071553290.390
negative regulation of osteoblast proliferationGO:003368940.387
cell cycle arrestGO:0007050370.385
activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome cGO:000863540.379
cellular response to organonitrogen compoundGO:00714171450.378
regulation of kinase activityGO:00435492490.374
signal transduction in absence of ligandGO:0038034550.371
mesonephros developmentGO:0001823970.370
nucleoside phosphate catabolic processGO:19012922220.370
striated muscle tissue developmentGO:00147062930.367
regulation of cysteine type endopeptidase activityGO:2000116650.364
response to epidermal growth factorGO:007084940.362
positive regulation of interleukin 10 secretionGO:200118110.360
positive regulation of leukocyte differentiationGO:1902107860.357
glycosyl compound catabolic processGO:19016582060.357
negative regulation of hydrolase activityGO:0051346710.356
regulation of protein complex assemblyGO:0043254830.354
monocarboxylic acid metabolic processGO:00327871910.347
oogenesisGO:0048477560.347
response to decreased oxygen levelsGO:0036293590.346
Human Worm Fly
guanosine containing compound catabolic processGO:19010691440.343
ureteric bud developmentGO:0001657940.340
activation of ral gtpase activityGO:003285930.338
positive regulation of reactive oxygen species metabolic processGO:2000379110.336
pallium developmentGO:00215431200.335
negative regulation of cell growthGO:0030308440.333
negative regulation of oxidative stress induced cell deathGO:190320290.333
protein modification by small protein conjugation or removalGO:00706472070.332
Human Fly
regulation of ras protein signal transductionGO:00465781140.330
tor signalingGO:0031929210.329
female gamete generationGO:0007292740.322
dna metabolic processGO:00062593030.322
receptor biosynthetic processGO:003280030.322
regulation of intrinsic apoptotic signaling pathwayGO:2001242610.319
regulation of ion transportGO:00432692150.319
bmp signaling pathwayGO:0030509930.315
regulation of protein serine threonine kinase activityGO:00719001570.313
regulation of reactive oxygen species metabolic processGO:2000377400.310
cation transportGO:00068123990.310
modulation by virus of host morphology or physiologyGO:001904830.309
positive regulation of cellular amine metabolic processGO:003324050.308
cellular response to peptide hormone stimulusGO:0071375920.306
coagulationGO:0050817780.305
epithelial cell differentiation involved in mammary gland alveolus developmentGO:006103040.303
positive regulation of cellular amino acid metabolic processGO:004576430.300
membrane organizationGO:00610242450.300
protein insertion into mitochondrial membraneGO:005120440.300
response to ionizing radiationGO:0010212420.297
modification dependent macromolecule catabolic processGO:00436321330.296
myeloid cell differentiationGO:00300992330.296
Zebrafish
positive regulation of protein targeting to membraneGO:009031470.296
epithelial tube morphogenesisGO:00605623030.296
spermatogenesisGO:00072832840.295
cellular response to drugGO:0035690150.294
digestive tract developmentGO:00485651900.290
response to increased oxygen levelsGO:003629620.289
axonogenesisGO:00074092740.285
Worm
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436230.284
metal ion homeostasisGO:00550651890.284
b cell homeostasisGO:0001782340.283
positive regulation of t cell differentiationGO:0045582520.283
regulation of protein kinase activityGO:00458592320.282
response to hypoxiaGO:0001666580.281
Human Worm Fly
positive regulation of protein kinase activityGO:00458601440.279
regulation of sequence specific dna binding transcription factor activityGO:00510901060.279
purine ribonucleotide catabolic processGO:00091542080.278
cellular response to x rayGO:007148120.277
ral protein signal transductionGO:003248420.276
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192550.274
digestive system developmentGO:00551232000.274
photoreceptor cell differentiationGO:0046530520.273
positive regulation of cell deathGO:00109422240.272
negative regulation of neuron deathGO:1901215980.271
apoptotic process involved in embryonic digit morphogenesisGO:190226330.268
regulation of actin filament based processGO:0032970990.268
cellular protein catabolic processGO:00442571550.267
labyrinthine layer developmentGO:0060711490.266
regulation of t cell activationGO:00508631700.266
response to peptideGO:19016521360.265
establishment of protein localization to plasma membraneGO:0090002340.264
positive regulation of transcription by galactoseGO:000041110.264
purine ribonucleoside catabolic processGO:00461302050.263
cytosolic calcium ion transportGO:0060401480.261
response to vitamin dGO:003328030.259
cellular response to cytokine stimulusGO:00713451890.259
peptidyl serine phosphorylationGO:0018105740.257
maintenance of locationGO:0051235890.257
cellular response to ionizing radiationGO:0071479110.257
nucleotide catabolic processGO:00091662170.257
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244250.257
regulation of t cell differentiationGO:0045580830.256
regulation of epithelial cell proliferationGO:00506781410.255
positive t cell selectionGO:0043368230.255
renal system developmentGO:00720012250.252
negative regulation of insulin receptor signaling pathwayGO:0046627140.252
cell agingGO:0007569350.251
regulation of cellular response to growth factor stimulusGO:0090287820.251
Zebrafish
metanephric glomerular mesangial cell proliferation involved in metanephros developmentGO:007226230.250
cellular lipid metabolic processGO:00442553230.246
regulation of leukocyte proliferationGO:00706631210.246
negative regulation of intracellular signal transductionGO:19025321670.245
spermatid differentiationGO:00485151150.243
regulation of coagulationGO:0050818310.243
ribonucleotide catabolic processGO:00092612080.238
negative regulation of cellular response to insulin stimulusGO:1900077160.238
regulation of actin cytoskeleton organizationGO:0032956840.237
positive regulation of glucose import in response to insulin stimulusGO:200127550.237
interleukin 10 secretionGO:007260840.236
regulation of map kinase activityGO:00434051200.236
regulation of transcription from rna polymerase ii promoter in response to oxidative stressGO:004361920.232
cellular response to erythropoietinGO:003601810.232
nucleobase containing small molecule metabolic processGO:00550863520.230
positive regulation of interleukin 13 secretionGO:200066710.229
learningGO:0007612980.229
t helper 2 cell activationGO:003571220.227
development of primary sexual characteristicsGO:00451371430.227
negative regulation of fibroblast proliferationGO:0048147140.227
regulation of vasculature developmentGO:1901342880.225
Zebrafish
regulation of actin polymerization or depolymerizationGO:0008064450.224
regulation of cellular component biogenesisGO:00440871810.224
response to organic cyclic compoundGO:00140701980.224
regulation of tor signalingGO:0032006170.224
protein targetingGO:00066051430.223
heart trabecula formationGO:0060347140.223
protein insertion into mitochondrial membrane involved in apoptotic signaling pathwayGO:000184440.221
response to mineralocorticoidGO:005138510.219
cell junction maintenanceGO:003433140.219
organic cyclic compound catabolic processGO:19013612950.215
response to purine containing compoundGO:0014074280.215
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600330.215
positive regulation of endopeptidase activityGO:0010950430.214
macromolecule catabolic processGO:00090572810.214
regulation of endothelial cell apoptotic processGO:200035190.213
renal tubule morphogenesisGO:0061333720.213
angiogenesisGO:00015252010.212
nucleoside metabolic processGO:00091162460.210
positive regulation of t helper 2 cell activationGO:200057020.208
regulation of homeostatic processGO:00328441820.208
axon ensheathmentGO:0008366760.207
response to extracellular stimulusGO:00099911270.207
carbohydrate metabolic processGO:00059752300.207
morphogenesis of a branching epitheliumGO:00611381930.205
regulation of protein maturationGO:1903317960.203
negative regulation of growthGO:0045926990.203
spongiotrophoblast layer developmentGO:0060712150.202
canonical wnt signaling pathwayGO:00600701300.202
sprouting angiogenesisGO:0002040260.201
regulation of endopeptidase activityGO:0052548890.201
regulation of anoikisGO:200020920.201
regulation of proteolysis involved in cellular protein catabolic processGO:1903050560.200
protein localization to endosomeGO:003601020.200
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919270.199
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237450.199
regulation of proteolysisGO:00301621640.197
regulation of cell adhesionGO:00301551540.197
regulation of reproductive processGO:2000241660.194
regulation of myeloid cell differentiationGO:0045637960.192
negative regulation of glial cell proliferationGO:006025340.192
positive regulation of calcium ion transportGO:0051928270.190
reactive nitrogen species metabolic processGO:200105700.189
4 hydroxyproline metabolic processGO:001947150.189
regulation of protein processingGO:0070613960.188
regulation of cyclic nucleotide metabolic processGO:0030799400.187
regulation of interleukin 13 secretionGO:200066520.187
multicellular organismal signalingGO:0035637910.187
regulation of thymocyte apoptotic processGO:0070243140.187
carbohydrate derivative catabolic processGO:19011362310.186
regulation of mammary gland involutionGO:190351940.185
interleukin 5 secretionGO:007260320.185
negative regulation of phosphorylationGO:00423261660.185
dna repairGO:00062811070.184
gtp metabolic processGO:00460391440.184
microtubule based movementGO:0007018840.184
nuclear exportGO:0051168340.184
Fly
embryonic epithelial tube formationGO:00018381300.184
t helper 2 cell cytokine productionGO:003574540.183
positive regulation of melanocyte differentiationGO:004563650.182
t cell differentiation in thymusGO:0033077770.181
pole plasm assemblyGO:000731520.181
protein ubiquitinationGO:00165671710.181
Human Fly
reactive oxygen species biosynthetic processGO:190340980.180
positive regulation of t cell activationGO:00508701010.179
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015430.179
regulation of nucleotide catabolic processGO:00308111220.179
sphingolipid metabolic processGO:0006665450.176
axon cargo transportGO:0008088330.176
cellular response to epidermal growth factor stimulusGO:007136440.176
vesicle organizationGO:0016050600.176
learning or memoryGO:00076111480.175
regulation of myelinationGO:0031641200.175
glycolipid metabolic processGO:0006664250.174
response to x rayGO:0010165110.174
regulation of cellular ph reductionGO:003284720.174
regulation of intracellular protein transportGO:0033157820.174
nitric oxide biosynthetic processGO:0006809250.173
gtp catabolic processGO:00061841430.173
regulation of cellular component sizeGO:00325351210.173
tissue migrationGO:0090130680.172
aromatic compound catabolic processGO:00194392860.172
skeletal system developmentGO:00015013560.172
columnar cuboidal epithelial cell maturationGO:000206940.171
anagenGO:0042640130.171
multi multicellular organism processGO:00447061090.169
cellular response to nitric oxideGO:007173240.169
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrestGO:000697730.169
morphogenesis of a polarized epitheliumGO:0001738370.168
purine containing compound catabolic processGO:00725232130.168
cd4 positive alpha beta t cell cytokine productionGO:003574340.168
muscle cell developmentGO:00550011330.168
positive regulation of cell developmentGO:00107202370.167
microtubule based processGO:00070172360.167
Fly
ubiquitin dependent protein catabolic processGO:00065111290.166
hair cycle phaseGO:0044851160.166
carbon catabolite activation of transcriptionGO:004599140.166
myelinationGO:0042552740.166
regulation of melanocyte differentiationGO:004563470.165
heart morphogenesisGO:00030071780.164
ribonucleoside triphosphate catabolic processGO:00092031990.163
ion transmembrane transportGO:00342203610.163
mitotic cell cycle processGO:19030471590.163
Fly
cellular response to oxygen levelsGO:0071453200.160
Human Fly
regulation of cellular response to hypoxiaGO:190003720.160
Fly
regulation of mitochondrial membrane permeabilityGO:0046902170.159
positive regulation of vesicle fusionGO:003134020.159
positive regulation of cell activationGO:00508671580.159
neural fold formationGO:000184270.158
response to monosaccharideGO:0034284670.158
glucose importGO:0046323320.157
regulation of system processGO:00440572000.157
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiationGO:200072120.157
chemotaxisGO:00069352470.157
Worm
cardiac septum morphogenesisGO:0060411460.156
schwann cell differentiationGO:0014037260.156
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001240160.156
cellular response to extracellular stimulusGO:0031668810.156
regulation of ral protein signal transductionGO:003248540.156
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100430.155
neural tube formationGO:00018411080.155
cardiac endothelial cell differentiationGO:000334840.155
retina development in camera type eyeGO:00600411190.154
negative regulation of blood vessel morphogenesisGO:2000181250.154
response to oxidative stressGO:00069791230.154
asymmetric neuroblast divisionGO:005505910.154
oocyte constructionGO:000730820.154
interleukin 12 productionGO:0032615320.154
regulation of extrinsic apoptotic signaling pathwayGO:2001236770.153
regulation of protein import into nucleusGO:0042306520.152
negative regulation of molecular functionGO:00440922580.152
regulation of synaptic growth at neuromuscular junctionGO:000858240.152
positive regulation of cyclin dependent protein serine threonine kinase activityGO:004573760.151
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238340.151
purine nucleotide catabolic processGO:00061952110.150
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161880.150
adherens junction maintenanceGO:003433410.150
nephron tubule developmentGO:0072080840.149
regulation of smad protein import into nucleusGO:006039030.149
leukocyte tethering or rollingGO:005090130.149
regulation of canonical wnt signaling pathwayGO:0060828820.148
negative regulation of mitotic cell cycleGO:0045930580.148
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280360.147
negative regulation of map kinase activityGO:0043407340.147
positive regulation of nucleotide metabolic processGO:00459811140.147
positive regulation of reactive oxygen species biosynthetic processGO:190342820.147
regulation of calcium ion transport into cytosolGO:0010522310.146
neuron deathGO:00709971540.146
cytokine mediated signaling pathwayGO:00192211150.145
response to endoplasmic reticulum stressGO:0034976530.145
purine ribonucleoside metabolic processGO:00461282410.145
nuclear transportGO:00511691390.145
response to corticosteroidGO:0031960200.144
g1 s transition of mitotic cell cycleGO:0000082570.144
regulation of glomerular mesangial cell proliferationGO:007212410.144
positive regulation of cysteine type endopeptidase activityGO:2001056390.143
positive regulation of neuron apoptotic processGO:0043525250.143
tube formationGO:00351481400.143
Fly
immune effector processGO:00022523210.143
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573690.141
protein oligomerizationGO:0051259670.140
t helper cell differentiationGO:0042093280.140
immune response activating cell surface receptor signaling pathwayGO:0002429720.139
hindbrain developmentGO:00309021280.139
positive regulation of neuron deathGO:1901216280.139
outflow tract morphogenesisGO:0003151530.139
morphogenesis of embryonic epitheliumGO:00163311590.138
maternal placenta developmentGO:0001893200.138
positive regulation of autophagyGO:001050890.138
hematopoietic progenitor cell differentiationGO:00022441430.137
cell proliferation involved in heart valve morphogenesisGO:000324910.137
oocyte differentiationGO:0009994350.137
mitochondrial outer membrane permeabilizationGO:0097345100.137
filopodium assemblyGO:0046847190.136
positive regulation of bmp signaling pathwayGO:0030513230.136
response to oxygen levelsGO:0070482620.136
Human Worm Fly
regulation of transcription by galactoseGO:000040910.136
cellular response to starvationGO:0009267570.136

Vhl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.933
Human
cancerDOID:16200.799
Human
endocrine gland cancerDOID:17000.200
organ system cancerDOID:005068600.200
Human