| release of cytochrome c from mitochondria | GO:0001836 | 23 | 0.999 | |
| positive regulation of apoptotic process involved in mammary gland involution | GO:0060058 | 4 | 0.991 | |
| regulation of dna templated transcription in response to stress | GO:0043620 | 9 | 0.988 | Human |
| regulation of transcription from rna polymerase ii promoter in response to stress | GO:0043618 | 8 | 0.975 | Human |
| urogenital system development | GO:0001655 | 261 | 0.970 | |
| activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway | GO:0097296 | 2 | 0.963 | |
| gas homeostasis | GO:0033483 | 3 | 0.949 | |
| glial cell apoptotic process | GO:0034349 | 3 | 0.946 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.945 | |
| hypoxia inducible factor 1alpha signaling pathway | GO:0097411 | 2 | 0.928 | |
| mesonephric tubule development | GO:0072164 | 94 | 0.920 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.913 | |
| mitochondrion organization | GO:0007005 | 134 | 0.905 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.896 | |
| response to peptide hormone | GO:0043434 | 127 | 0.876 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 95 | 0.869 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.868 | |
| erythrocyte differentiation | GO:0030218 | 88 | 0.866 | Zebrafish |
| kidney development | GO:0001822 | 213 | 0.865 | |
| positive regulation of glial cell proliferation | GO:0060252 | 4 | 0.861 | |
| positive regulation of apoptotic process involved in morphogenesis | GO:1902339 | 4 | 0.853 | |
| establishment or maintenance of cytoskeleton polarity | GO:0030952 | 2 | 0.850 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.843 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.840 | |
| negative regulation of release of cytochrome c from mitochondria | GO:0090201 | 6 | 0.837 | |
| cellular response to insulin stimulus | GO:0032869 | 78 | 0.836 | |
| activation of cysteine type endopeptidase activity | GO:0097202 | 27 | 0.833 | |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.827 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.822 | |
| extrinsic apoptotic signaling pathway via death domain receptors | GO:0008625 | 34 | 0.818 | |
| regulation of neuron death | GO:1901214 | 134 | 0.807 | |
| embryonic placenta development | GO:0001892 | 98 | 0.801 | |
| establishment or maintenance of microtubule cytoskeleton polarity | GO:0030951 | 1 | 0.798 | |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway | GO:2001269 | 3 | 0.784 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.781 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.762 | Zebrafish |
| action potential | GO:0001508 | 78 | 0.761 | |
| b 1 b cell homeostasis | GO:0001922 | 4 | 0.760 | |
| negative regulation of peptidyl tyrosine phosphorylation | GO:0050732 | 17 | 0.759 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.757 | |
| neuronal action potential | GO:0019228 | 54 | 0.753 | |
| protein processing | GO:0016485 | 163 | 0.751 | |
| blood coagulation | GO:0007596 | 76 | 0.750 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.745 | |
| inflammatory response | GO:0006954 | 244 | 0.741 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.727 | |
| cellular response to decreased oxygen levels | GO:0036294 | 18 | 0.727 | Human Fly |
| ameboidal type cell migration | GO:0001667 | 128 | 0.724 | |
| negative regulation of protein phosphorylation | GO:0001933 | 126 | 0.720 | |
| regulation of protein targeting | GO:1903533 | 61 | 0.719 | |
| muscle tissue development | GO:0060537 | 308 | 0.717 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.715 | |
| metanephric glomerular mesangium development | GO:0072223 | 3 | 0.710 | |
| apoptotic process involved in mammary gland involution | GO:0060057 | 4 | 0.709 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.709 | |
| hemostasis | GO:0007599 | 78 | 0.707 | |
| negative regulation of lymphocyte apoptotic process | GO:0070229 | 24 | 0.701 | |
| negative regulation of anoikis | GO:2000811 | 2 | 0.700 | |
| apoptotic mitochondrial changes | GO:0008637 | 48 | 0.699 | |
| maternal process involved in female pregnancy | GO:0060135 | 32 | 0.699 | |
| positive regulation of nervous system development | GO:0051962 | 221 | 0.693 | |
| endothelial cell apoptotic process | GO:0072577 | 9 | 0.690 | |
| response to corticosterone | GO:0051412 | 1 | 0.680 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway | GO:2001267 | 4 | 0.679 | |
| thymocyte apoptotic process | GO:0070242 | 19 | 0.669 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.658 | |
| digestive tract morphogenesis | GO:0048546 | 147 | 0.655 | |
| germ cell development | GO:0007281 | 185 | 0.653 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.649 | |
| inflammatory response to wounding | GO:0090594 | 4 | 0.649 | |
| blood vessel morphogenesis | GO:0048514 | 285 | 0.648 | |
| regulation of ral gtpase activity | GO:0032315 | 4 | 0.646 | |
| positive regulation of mitochondrial membrane permeability involved in apoptotic process | GO:1902110 | 11 | 0.646 | |
| regulation of neuron apoptotic process | GO:0043523 | 122 | 0.641 | |
| intrinsic apoptotic signaling pathway by p53 class mediator | GO:0072332 | 35 | 0.641 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.639 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.638 | |
| placenta development | GO:0001890 | 140 | 0.634 | |
| lymphocyte homeostasis | GO:0002260 | 64 | 0.624 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.622 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.617 | |
| regulation of mitochondrion organization | GO:0010821 | 27 | 0.614 | |
| regulation of hemostasis | GO:1900046 | 28 | 0.613 | |
| protein catabolic process | GO:0030163 | 221 | 0.611 | |
| autophagy | GO:0006914 | 45 | 0.607 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.600 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 62 | 0.600 | |
| lactation | GO:0007595 | 25 | 0.599 | |
| connective tissue replacement involved in inflammatory response wound healing | GO:0002248 | 3 | 0.593 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.592 | |
| glycoprotein metabolic process | GO:0009100 | 116 | 0.579 | |
| formation of radial glial scaffolds | GO:0021943 | 4 | 0.578 | |
| t cell activation | GO:0042110 | 289 | 0.578 | |
| single organism cell adhesion | GO:0098602 | 156 | 0.576 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.575 | |
| response to radiation | GO:0009314 | 165 | 0.572 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.570 | |
| neuron apoptotic process | GO:0051402 | 142 | 0.564 | |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.556 | |
| transmission of nerve impulse | GO:0019226 | 76 | 0.552 | |
| positive regulation of t helper 2 cell cytokine production | GO:2000553 | 3 | 0.551 | |
| amine metabolic process | GO:0009308 | 45 | 0.551 | |
| response to insulin | GO:0032868 | 100 | 0.550 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.550 | |
| cellular response to gamma radiation | GO:0071480 | 4 | 0.548 | |
| positive regulation of leukocyte proliferation | GO:0070665 | 73 | 0.547 | |
| glycogen cell differentiation involved in embryonic placenta development | GO:0060709 | 1 | 0.546 | |
| intrinsic apoptotic signaling pathway in response to oxidative stress | GO:0008631 | 19 | 0.545 | |
| regulation of release of cytochrome c from mitochondria | GO:0090199 | 11 | 0.541 | |
| intracellular protein transport | GO:0006886 | 204 | 0.539 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 126 | 0.537 | |
| cell growth | GO:0016049 | 130 | 0.537 | |
| cellular response to peptide | GO:1901653 | 92 | 0.536 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.536 | |
| neuroblast proliferation | GO:0007405 | 49 | 0.535 | |
| myelination in peripheral nervous system | GO:0022011 | 19 | 0.535 | |
| kidney epithelium development | GO:0072073 | 121 | 0.532 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.522 | |
| cellular response to light stimulus | GO:0071482 | 19 | 0.521 | |
| regulation of cyclin dependent protein serine threonine kinase activity | GO:0000079 | 16 | 0.520 | |
| regulation of endothelial cell chemotaxis | GO:2001026 | 1 | 0.518 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.513 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.512 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.511 | |
| regulation of protein localization | GO:0032880 | 231 | 0.509 | |
| positive regulation of extrinsic apoptotic signaling pathway via death domain receptors | GO:1902043 | 13 | 0.504 | |
| myeloid cell homeostasis | GO:0002262 | 114 | 0.498 | Zebrafish |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.497 | Fly |
| neural tube development | GO:0021915 | 160 | 0.494 | |
| actin filament organization | GO:0007015 | 113 | 0.494 | |
| connective tissue development | GO:0061448 | 179 | 0.492 | |
| regulation of erythrocyte differentiation | GO:0045646 | 23 | 0.491 | |
| oxygen homeostasis | GO:0032364 | 2 | 0.489 | |
| positive regulation of b cell apoptotic process | GO:0002904 | 4 | 0.489 | |
| positive regulation of mammary gland involution | GO:1903521 | 4 | 0.487 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.485 | |
| establishment or maintenance of cell polarity | GO:0007163 | 86 | 0.484 | Fly |
| negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway | GO:1902176 | 4 | 0.482 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.477 | Fly |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.476 | |
| t cell apoptotic process | GO:0070231 | 39 | 0.472 | |
| cellular response to oxidative stress | GO:0034599 | 76 | 0.470 | |
| negative regulation of tor signaling | GO:0032007 | 13 | 0.469 | |
| regulation of blood coagulation | GO:0030193 | 28 | 0.468 | |
| cellular response to radiation | GO:0071478 | 28 | 0.467 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 46 | 0.465 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.465 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.464 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.464 | |
| substrate dependent cell migration cell extension | GO:0006930 | 4 | 0.464 | |
| positive regulation of cell proliferation involved in heart valve morphogenesis | GO:0003251 | 1 | 0.463 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.462 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.457 | |
| axon transport of mitochondrion | GO:0019896 | 2 | 0.456 | |
| mesonephric epithelium development | GO:0072163 | 94 | 0.454 | |
| regulation of fibroblast proliferation | GO:0048145 | 34 | 0.450 | |
| glucose import in response to insulin stimulus | GO:0044381 | 8 | 0.450 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.449 | Human Fly |
| negative regulation of neuron apoptotic process | GO:0043524 | 92 | 0.448 | |
| response to granulocyte macrophage colony stimulating factor | GO:0097012 | 3 | 0.447 | |
| positive regulation of interleukin 5 secretion | GO:2000664 | 1 | 0.447 | |
| regulation of insulin receptor signaling pathway | GO:0046626 | 21 | 0.446 | |
| response to growth factor | GO:0070848 | 198 | 0.445 | Zebrafish |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.439 | Zebrafish |
| negative regulation of intrinsic apoptotic signaling pathway | GO:2001243 | 34 | 0.439 | |
| hindbrain radial glia guided cell migration | GO:0021932 | 12 | 0.439 | |
| response to light stimulus | GO:0009416 | 135 | 0.436 | |
| wound healing involved in inflammatory response | GO:0002246 | 4 | 0.433 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.432 | |
| regulation of wound healing | GO:0061041 | 40 | 0.431 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.422 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.422 | |
| regulation of response to oxidative stress | GO:1902882 | 19 | 0.420 | |
| signal transduction by p53 class mediator | GO:0072331 | 51 | 0.419 | |
| skeletal muscle organ development | GO:0060538 | 163 | 0.419 | |
| protein export from nucleus | GO:0006611 | 20 | 0.418 | Fly |
| regulation of angiogenesis | GO:0045765 | 81 | 0.414 | Zebrafish |
| regulation of peptidase activity | GO:0052547 | 96 | 0.413 | |
| regulation of cellular protein catabolic process | GO:1903362 | 61 | 0.412 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.408 | |
| mammary gland involution | GO:0060056 | 9 | 0.405 | |
| organelle fusion | GO:0048284 | 28 | 0.404 | |
| response to nitric oxide | GO:0071731 | 4 | 0.404 | |
| zymogen activation | GO:0031638 | 41 | 0.400 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.400 | |
| positive regulation of smooth muscle cell migration | GO:0014911 | 4 | 0.398 | |
| neural precursor cell proliferation | GO:0061351 | 121 | 0.398 | |
| regulation of cell activation | GO:0050865 | 289 | 0.396 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.396 | |
| neuron projection extension | GO:1990138 | 64 | 0.394 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.394 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.393 | |
| regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway | GO:1903376 | 3 | 0.391 | |
| regulation of body fluid levels | GO:0050878 | 162 | 0.391 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 139 | 0.390 | |
| protein maturation | GO:0051604 | 176 | 0.390 | |
| cell adhesion | GO:0007155 | 329 | 0.390 | |
| negative regulation of osteoblast proliferation | GO:0033689 | 4 | 0.387 | |
| cell cycle arrest | GO:0007050 | 37 | 0.385 | |
| activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c | GO:0008635 | 4 | 0.379 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.378 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.374 | |
| signal transduction in absence of ligand | GO:0038034 | 55 | 0.371 | |
| mesonephros development | GO:0001823 | 97 | 0.370 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.370 | |
| striated muscle tissue development | GO:0014706 | 293 | 0.367 | |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 65 | 0.364 | |
| response to epidermal growth factor | GO:0070849 | 4 | 0.362 | |
| positive regulation of interleukin 10 secretion | GO:2001181 | 1 | 0.360 | |
| positive regulation of leukocyte differentiation | GO:1902107 | 86 | 0.357 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.357 | |
| negative regulation of hydrolase activity | GO:0051346 | 71 | 0.356 | |
| regulation of protein complex assembly | GO:0043254 | 83 | 0.354 | |
| monocarboxylic acid metabolic process | GO:0032787 | 191 | 0.347 | |
| oogenesis | GO:0048477 | 56 | 0.347 | |
| response to decreased oxygen levels | GO:0036293 | 59 | 0.346 | Human Worm Fly |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.343 | |
| ureteric bud development | GO:0001657 | 94 | 0.340 | |
| activation of ral gtpase activity | GO:0032859 | 3 | 0.338 | |
| positive regulation of reactive oxygen species metabolic process | GO:2000379 | 11 | 0.336 | |
| pallium development | GO:0021543 | 120 | 0.335 | |
| negative regulation of cell growth | GO:0030308 | 44 | 0.333 | |
| negative regulation of oxidative stress induced cell death | GO:1903202 | 9 | 0.333 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.332 | Human Fly |
| regulation of ras protein signal transduction | GO:0046578 | 114 | 0.330 | |
| tor signaling | GO:0031929 | 21 | 0.329 | |
| female gamete generation | GO:0007292 | 74 | 0.322 | |
| dna metabolic process | GO:0006259 | 303 | 0.322 | |
| receptor biosynthetic process | GO:0032800 | 3 | 0.322 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 61 | 0.319 | |
| regulation of ion transport | GO:0043269 | 215 | 0.319 | |
| bmp signaling pathway | GO:0030509 | 93 | 0.315 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.313 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 40 | 0.310 | |
| cation transport | GO:0006812 | 399 | 0.310 | |
| modulation by virus of host morphology or physiology | GO:0019048 | 3 | 0.309 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.308 | |
| cellular response to peptide hormone stimulus | GO:0071375 | 92 | 0.306 | |
| coagulation | GO:0050817 | 78 | 0.305 | |
| epithelial cell differentiation involved in mammary gland alveolus development | GO:0061030 | 4 | 0.303 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.300 | |
| membrane organization | GO:0061024 | 245 | 0.300 | |
| protein insertion into mitochondrial membrane | GO:0051204 | 4 | 0.300 | |
| response to ionizing radiation | GO:0010212 | 42 | 0.297 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.296 | |
| myeloid cell differentiation | GO:0030099 | 233 | 0.296 | Zebrafish |
| positive regulation of protein targeting to membrane | GO:0090314 | 7 | 0.296 | |
| epithelial tube morphogenesis | GO:0060562 | 303 | 0.296 | |
| spermatogenesis | GO:0007283 | 284 | 0.295 | |
| cellular response to drug | GO:0035690 | 15 | 0.294 | |
| digestive tract development | GO:0048565 | 190 | 0.290 | |
| response to increased oxygen levels | GO:0036296 | 2 | 0.289 | |
| axonogenesis | GO:0007409 | 274 | 0.285 | Worm |
| positive regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032436 | 23 | 0.284 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.284 | |
| b cell homeostasis | GO:0001782 | 34 | 0.283 | |
| positive regulation of t cell differentiation | GO:0045582 | 52 | 0.283 | |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.282 | |
| response to hypoxia | GO:0001666 | 58 | 0.281 | Human Worm Fly |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.279 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 106 | 0.279 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.278 | |
| cellular response to x ray | GO:0071481 | 2 | 0.277 | |
| ral protein signal transduction | GO:0032484 | 2 | 0.276 | |
| extrinsic apoptotic signaling pathway in absence of ligand | GO:0097192 | 55 | 0.274 | |
| digestive system development | GO:0055123 | 200 | 0.274 | |
| photoreceptor cell differentiation | GO:0046530 | 52 | 0.273 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.272 | |
| negative regulation of neuron death | GO:1901215 | 98 | 0.271 | |
| apoptotic process involved in embryonic digit morphogenesis | GO:1902263 | 3 | 0.268 | |
| regulation of actin filament based process | GO:0032970 | 99 | 0.268 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.267 | |
| labyrinthine layer development | GO:0060711 | 49 | 0.266 | |
| regulation of t cell activation | GO:0050863 | 170 | 0.266 | |
| response to peptide | GO:1901652 | 136 | 0.265 | |
| establishment of protein localization to plasma membrane | GO:0090002 | 34 | 0.264 | |
| positive regulation of transcription by galactose | GO:0000411 | 1 | 0.264 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.263 | |
| cytosolic calcium ion transport | GO:0060401 | 48 | 0.261 | |
| response to vitamin d | GO:0033280 | 3 | 0.259 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.259 | |
| peptidyl serine phosphorylation | GO:0018105 | 74 | 0.257 | |
| maintenance of location | GO:0051235 | 89 | 0.257 | |
| cellular response to ionizing radiation | GO:0071479 | 11 | 0.257 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.257 | |
| positive regulation of intrinsic apoptotic signaling pathway | GO:2001244 | 25 | 0.257 | |
| regulation of t cell differentiation | GO:0045580 | 83 | 0.256 | |
| regulation of epithelial cell proliferation | GO:0050678 | 141 | 0.255 | |
| positive t cell selection | GO:0043368 | 23 | 0.255 | |
| renal system development | GO:0072001 | 225 | 0.252 | |
| negative regulation of insulin receptor signaling pathway | GO:0046627 | 14 | 0.252 | |
| cell aging | GO:0007569 | 35 | 0.251 | |
| regulation of cellular response to growth factor stimulus | GO:0090287 | 82 | 0.251 | Zebrafish |
| metanephric glomerular mesangial cell proliferation involved in metanephros development | GO:0072262 | 3 | 0.250 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.246 | |
| regulation of leukocyte proliferation | GO:0070663 | 121 | 0.246 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.245 | |
| spermatid differentiation | GO:0048515 | 115 | 0.243 | |
| regulation of coagulation | GO:0050818 | 31 | 0.243 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.238 | |
| negative regulation of cellular response to insulin stimulus | GO:1900077 | 16 | 0.238 | |
| regulation of actin cytoskeleton organization | GO:0032956 | 84 | 0.237 | |
| positive regulation of glucose import in response to insulin stimulus | GO:2001275 | 5 | 0.237 | |
| interleukin 10 secretion | GO:0072608 | 4 | 0.236 | |
| regulation of map kinase activity | GO:0043405 | 120 | 0.236 | |
| regulation of transcription from rna polymerase ii promoter in response to oxidative stress | GO:0043619 | 2 | 0.232 | |
| cellular response to erythropoietin | GO:0036018 | 1 | 0.232 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.230 | |
| positive regulation of interleukin 13 secretion | GO:2000667 | 1 | 0.229 | |
| learning | GO:0007612 | 98 | 0.229 | |
| t helper 2 cell activation | GO:0035712 | 2 | 0.227 | |
| development of primary sexual characteristics | GO:0045137 | 143 | 0.227 | |
| negative regulation of fibroblast proliferation | GO:0048147 | 14 | 0.227 | |
| regulation of vasculature development | GO:1901342 | 88 | 0.225 | Zebrafish |
| regulation of actin polymerization or depolymerization | GO:0008064 | 45 | 0.224 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.224 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.224 | |
| regulation of tor signaling | GO:0032006 | 17 | 0.224 | |
| protein targeting | GO:0006605 | 143 | 0.223 | |
| heart trabecula formation | GO:0060347 | 14 | 0.223 | |
| protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | GO:0001844 | 4 | 0.221 | |
| response to mineralocorticoid | GO:0051385 | 1 | 0.219 | |
| cell junction maintenance | GO:0034331 | 4 | 0.219 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.215 | |
| response to purine containing compound | GO:0014074 | 28 | 0.215 | |
| positive regulation of transcription from rna polymerase ii promoter in response to stress | GO:0036003 | 3 | 0.215 | |
| positive regulation of endopeptidase activity | GO:0010950 | 43 | 0.214 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.214 | |
| regulation of endothelial cell apoptotic process | GO:2000351 | 9 | 0.213 | |
| renal tubule morphogenesis | GO:0061333 | 72 | 0.213 | |
| angiogenesis | GO:0001525 | 201 | 0.212 | |
| nucleoside metabolic process | GO:0009116 | 246 | 0.210 | |
| positive regulation of t helper 2 cell activation | GO:2000570 | 2 | 0.208 | |
| regulation of homeostatic process | GO:0032844 | 182 | 0.208 | |
| axon ensheathment | GO:0008366 | 76 | 0.207 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.207 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.207 | |
| morphogenesis of a branching epithelium | GO:0061138 | 193 | 0.205 | |
| regulation of protein maturation | GO:1903317 | 96 | 0.203 | |
| negative regulation of growth | GO:0045926 | 99 | 0.203 | |
| spongiotrophoblast layer development | GO:0060712 | 15 | 0.202 | |
| canonical wnt signaling pathway | GO:0060070 | 130 | 0.202 | |
| sprouting angiogenesis | GO:0002040 | 26 | 0.201 | |
| regulation of endopeptidase activity | GO:0052548 | 89 | 0.201 | |
| regulation of anoikis | GO:2000209 | 2 | 0.201 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 56 | 0.200 | |
| protein localization to endosome | GO:0036010 | 2 | 0.200 | |
| activation of cysteine type endopeptidase activity involved in apoptotic process | GO:0006919 | 27 | 0.199 | |
| negative regulation of extrinsic apoptotic signaling pathway | GO:2001237 | 45 | 0.199 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.197 | |
| regulation of cell adhesion | GO:0030155 | 154 | 0.197 | |
| regulation of reproductive process | GO:2000241 | 66 | 0.194 | |
| regulation of myeloid cell differentiation | GO:0045637 | 96 | 0.192 | |
| negative regulation of glial cell proliferation | GO:0060253 | 4 | 0.192 | |
| positive regulation of calcium ion transport | GO:0051928 | 27 | 0.190 | |
| reactive nitrogen species metabolic process | GO:2001057 | 0 | 0.189 | |
| 4 hydroxyproline metabolic process | GO:0019471 | 5 | 0.189 | |
| regulation of protein processing | GO:0070613 | 96 | 0.188 | |
| regulation of cyclic nucleotide metabolic process | GO:0030799 | 40 | 0.187 | |
| regulation of interleukin 13 secretion | GO:2000665 | 2 | 0.187 | |
| multicellular organismal signaling | GO:0035637 | 91 | 0.187 | |
| regulation of thymocyte apoptotic process | GO:0070243 | 14 | 0.187 | |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.186 | |
| regulation of mammary gland involution | GO:1903519 | 4 | 0.185 | |
| interleukin 5 secretion | GO:0072603 | 2 | 0.185 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.185 | |
| dna repair | GO:0006281 | 107 | 0.184 | |
| gtp metabolic process | GO:0046039 | 144 | 0.184 | |
| microtubule based movement | GO:0007018 | 84 | 0.184 | |
| nuclear export | GO:0051168 | 34 | 0.184 | Fly |
| embryonic epithelial tube formation | GO:0001838 | 130 | 0.184 | |
| t helper 2 cell cytokine production | GO:0035745 | 4 | 0.183 | |
| positive regulation of melanocyte differentiation | GO:0045636 | 5 | 0.182 | |
| t cell differentiation in thymus | GO:0033077 | 77 | 0.181 | |
| pole plasm assembly | GO:0007315 | 2 | 0.181 | |
| protein ubiquitination | GO:0016567 | 171 | 0.181 | Human Fly |
| reactive oxygen species biosynthetic process | GO:1903409 | 8 | 0.180 | |
| positive regulation of t cell activation | GO:0050870 | 101 | 0.179 | |
| regulation of transforming growth factor beta receptor signaling pathway | GO:0017015 | 43 | 0.179 | |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.179 | |
| sphingolipid metabolic process | GO:0006665 | 45 | 0.176 | |
| axon cargo transport | GO:0008088 | 33 | 0.176 | |
| cellular response to epidermal growth factor stimulus | GO:0071364 | 4 | 0.176 | |
| vesicle organization | GO:0016050 | 60 | 0.176 | |
| learning or memory | GO:0007611 | 148 | 0.175 | |
| regulation of myelination | GO:0031641 | 20 | 0.175 | |
| glycolipid metabolic process | GO:0006664 | 25 | 0.174 | |
| response to x ray | GO:0010165 | 11 | 0.174 | |
| regulation of cellular ph reduction | GO:0032847 | 2 | 0.174 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.174 | |
| nitric oxide biosynthetic process | GO:0006809 | 25 | 0.173 | |
| gtp catabolic process | GO:0006184 | 143 | 0.173 | |
| regulation of cellular component size | GO:0032535 | 121 | 0.173 | |
| tissue migration | GO:0090130 | 68 | 0.172 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.172 | |
| skeletal system development | GO:0001501 | 356 | 0.172 | |
| columnar cuboidal epithelial cell maturation | GO:0002069 | 4 | 0.171 | |
| anagen | GO:0042640 | 13 | 0.171 | |
| multi multicellular organism process | GO:0044706 | 109 | 0.169 | |
| cellular response to nitric oxide | GO:0071732 | 4 | 0.169 | |
| dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest | GO:0006977 | 3 | 0.169 | |
| morphogenesis of a polarized epithelium | GO:0001738 | 37 | 0.168 | |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.168 | |
| cd4 positive alpha beta t cell cytokine production | GO:0035743 | 4 | 0.168 | |
| muscle cell development | GO:0055001 | 133 | 0.168 | |
| positive regulation of cell development | GO:0010720 | 237 | 0.167 | |
| microtubule based process | GO:0007017 | 236 | 0.167 | Fly |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.166 | |
| hair cycle phase | GO:0044851 | 16 | 0.166 | |
| carbon catabolite activation of transcription | GO:0045991 | 4 | 0.166 | |
| myelination | GO:0042552 | 74 | 0.166 | |
| regulation of melanocyte differentiation | GO:0045634 | 7 | 0.165 | |
| heart morphogenesis | GO:0003007 | 178 | 0.164 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.163 | |
| ion transmembrane transport | GO:0034220 | 361 | 0.163 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.163 | Fly |
| cellular response to oxygen levels | GO:0071453 | 20 | 0.160 | Human Fly |
| regulation of cellular response to hypoxia | GO:1900037 | 2 | 0.160 | Fly |
| regulation of mitochondrial membrane permeability | GO:0046902 | 17 | 0.159 | |
| positive regulation of vesicle fusion | GO:0031340 | 2 | 0.159 | |
| positive regulation of cell activation | GO:0050867 | 158 | 0.159 | |
| neural fold formation | GO:0001842 | 7 | 0.158 | |
| response to monosaccharide | GO:0034284 | 67 | 0.158 | |
| glucose import | GO:0046323 | 32 | 0.157 | |
| regulation of system process | GO:0044057 | 200 | 0.157 | |
| positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation | GO:2000721 | 2 | 0.157 | |
| chemotaxis | GO:0006935 | 247 | 0.157 | Worm |
| cardiac septum morphogenesis | GO:0060411 | 46 | 0.156 | |
| schwann cell differentiation | GO:0014037 | 26 | 0.156 | |
| negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | GO:2001240 | 16 | 0.156 | |
| cellular response to extracellular stimulus | GO:0031668 | 81 | 0.156 | |
| regulation of ral protein signal transduction | GO:0032485 | 4 | 0.156 | |
| positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090100 | 43 | 0.155 | |
| neural tube formation | GO:0001841 | 108 | 0.155 | |
| cardiac endothelial cell differentiation | GO:0003348 | 4 | 0.155 | |
| retina development in camera type eye | GO:0060041 | 119 | 0.154 | |
| negative regulation of blood vessel morphogenesis | GO:2000181 | 25 | 0.154 | |
| response to oxidative stress | GO:0006979 | 123 | 0.154 | |
| asymmetric neuroblast division | GO:0055059 | 1 | 0.154 | |
| oocyte construction | GO:0007308 | 2 | 0.154 | |
| interleukin 12 production | GO:0032615 | 32 | 0.154 | |
| regulation of extrinsic apoptotic signaling pathway | GO:2001236 | 77 | 0.153 | |
| regulation of protein import into nucleus | GO:0042306 | 52 | 0.152 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.152 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.152 | |
| positive regulation of cyclin dependent protein serine threonine kinase activity | GO:0045737 | 6 | 0.151 | |
| positive regulation of extrinsic apoptotic signaling pathway | GO:2001238 | 34 | 0.151 | |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.150 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.150 | |
| adherens junction maintenance | GO:0034334 | 1 | 0.150 | |
| nephron tubule development | GO:0072080 | 84 | 0.149 | |
| regulation of smad protein import into nucleus | GO:0060390 | 3 | 0.149 | |
| leukocyte tethering or rolling | GO:0050901 | 3 | 0.149 | |
| regulation of canonical wnt signaling pathway | GO:0060828 | 82 | 0.148 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 58 | 0.148 | |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043280 | 36 | 0.147 | |
| negative regulation of map kinase activity | GO:0043407 | 34 | 0.147 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 114 | 0.147 | |
| positive regulation of reactive oxygen species biosynthetic process | GO:1903428 | 2 | 0.147 | |
| regulation of calcium ion transport into cytosol | GO:0010522 | 31 | 0.146 | |
| neuron death | GO:0070997 | 154 | 0.146 | |
| cytokine mediated signaling pathway | GO:0019221 | 115 | 0.145 | |
| response to endoplasmic reticulum stress | GO:0034976 | 53 | 0.145 | |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.145 | |
| nuclear transport | GO:0051169 | 139 | 0.145 | |
| response to corticosteroid | GO:0031960 | 20 | 0.144 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 57 | 0.144 | |
| regulation of glomerular mesangial cell proliferation | GO:0072124 | 1 | 0.144 | |
| positive regulation of cysteine type endopeptidase activity | GO:2001056 | 39 | 0.143 | |
| positive regulation of neuron apoptotic process | GO:0043525 | 25 | 0.143 | |
| tube formation | GO:0035148 | 140 | 0.143 | Fly |
| immune effector process | GO:0002252 | 321 | 0.143 | |
| negative regulation of cyclin dependent protein serine threonine kinase activity | GO:0045736 | 9 | 0.141 | |
| protein oligomerization | GO:0051259 | 67 | 0.140 | |
| t helper cell differentiation | GO:0042093 | 28 | 0.140 | |
| immune response activating cell surface receptor signaling pathway | GO:0002429 | 72 | 0.139 | |
| hindbrain development | GO:0030902 | 128 | 0.139 | |
| positive regulation of neuron death | GO:1901216 | 28 | 0.139 | |
| outflow tract morphogenesis | GO:0003151 | 53 | 0.139 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 159 | 0.138 | |
| maternal placenta development | GO:0001893 | 20 | 0.138 | |
| positive regulation of autophagy | GO:0010508 | 9 | 0.138 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.137 | |
| cell proliferation involved in heart valve morphogenesis | GO:0003249 | 1 | 0.137 | |
| oocyte differentiation | GO:0009994 | 35 | 0.137 | |
| mitochondrial outer membrane permeabilization | GO:0097345 | 10 | 0.137 | |
| filopodium assembly | GO:0046847 | 19 | 0.136 | |
| positive regulation of bmp signaling pathway | GO:0030513 | 23 | 0.136 | |
| response to oxygen levels | GO:0070482 | 62 | 0.136 | Human Worm Fly |
| regulation of transcription by galactose | GO:0000409 | 1 | 0.136 | |
| cellular response to starvation | GO:0009267 | 57 | 0.136 | |
