| oxidation reduction process | GO:0055114 | 342 | 0.522 | |
| autophagy | GO:0006914 | 45 | 0.157 | Human |
| protein catabolic process | GO:0030163 | 221 | 0.118 | |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.116 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.113 | |
| response to extracellular stimulus | GO:0009991 | 127 | 0.088 | |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.086 | |
| macroautophagy | GO:0016236 | 21 | 0.085 | |
| cofactor metabolic process | GO:0051186 | 80 | 0.084 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.080 | |
| dna metabolic process | GO:0006259 | 303 | 0.078 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.077 | |
| protein processing | GO:0016485 | 163 | 0.072 | |
| cation transport | GO:0006812 | 399 | 0.066 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.063 | |
| cellular amine metabolic process | GO:0044106 | 44 | 0.063 | |
| dephosphorylation | GO:0016311 | 129 | 0.062 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.061 | |
| protein maturation | GO:0051604 | 176 | 0.060 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.059 | |
| cellular response to external stimulus | GO:0071496 | 88 | 0.058 | |
| membrane fusion | GO:0061025 | 38 | 0.055 | |
| cellular response to extracellular stimulus | GO:0031668 | 81 | 0.054 | |
| regulation of transcription from rna polymerase iii promoter | GO:0006359 | 2 | 0.054 | |
| small molecule catabolic process | GO:0044282 | 71 | 0.054 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.052 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.050 | |
| regulation of cellular protein catabolic process | GO:1903362 | 61 | 0.049 | |
| amine metabolic process | GO:0009308 | 45 | 0.048 | |
| nitrogen compound transport | GO:0071705 | 271 | 0.047 | |
| regulation of cell cycle | GO:0051726 | 281 | 0.047 | |
| cellular lipid catabolic process | GO:0044242 | 52 | 0.047 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.046 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.044 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.043 | |
| mitochondrion degradation | GO:0000422 | 3 | 0.041 | |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.040 | |
| regulation of binding | GO:0051098 | 111 | 0.040 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.040 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.040 | |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.040 | |
| regulation of protein maturation | GO:1903317 | 96 | 0.039 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.039 | |
| positive regulation of dopamine secretion | GO:0033603 | 2 | 0.038 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.037 | |
| spermatogenesis | GO:0007283 | 284 | 0.037 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.036 | |
| regulation of protein localization | GO:0032880 | 231 | 0.036 | |
| cellular response to nutrient levels | GO:0031669 | 64 | 0.036 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.036 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.035 | |
| male gamete generation | GO:0048232 | 285 | 0.034 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.034 | |
| regulation of homeostatic process | GO:0032844 | 182 | 0.033 | |
| organelle fusion | GO:0048284 | 28 | 0.033 | |
| positive regulation of tor signaling | GO:0032008 | 3 | 0.032 | |
| response to nutrient levels | GO:0031667 | 109 | 0.032 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.031 | |
| glucose homeostasis | GO:0042593 | 128 | 0.030 | |
| protein ubiquitination | GO:0016567 | 171 | 0.030 | |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.029 | |
| membrane organization | GO:0061024 | 245 | 0.029 | |
| mitotic cell cycle | GO:0000278 | 195 | 0.029 | |
| lateral inhibition | GO:0046331 | 1 | 0.028 | |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.028 | |
| generation of precursor metabolites and energy | GO:0006091 | 103 | 0.028 | |
| ossification | GO:0001503 | 216 | 0.028 | |
| cellular response to starvation | GO:0009267 | 57 | 0.027 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.027 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.027 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.027 | |
| positive regulation of homeostatic process | GO:0032846 | 64 | 0.027 | |
| defense response to other organism | GO:0098542 | 197 | 0.026 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.026 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.026 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.026 | |
| water transport | GO:0006833 | 12 | 0.026 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.026 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.026 | |
| monocarboxylic acid catabolic process | GO:0072329 | 27 | 0.025 | |
| transcription from rna polymerase iii promoter | GO:0006383 | 3 | 0.025 | |
| reactive nitrogen species metabolic process | GO:2001057 | 0 | 0.025 | |
| positive regulation of catecholamine secretion | GO:0033605 | 2 | 0.025 | |
| negative regulation of protein processing | GO:0010955 | 79 | 0.025 | |
| negative regulation of cellular catabolic process | GO:0031330 | 47 | 0.025 | |
| regulation of cell cycle phase transition | GO:1901987 | 77 | 0.024 | |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.024 | |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.024 | |
| monocarboxylic acid metabolic process | GO:0032787 | 191 | 0.023 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 40 | 0.023 | |
| regulation of protein transport | GO:0051223 | 163 | 0.023 | |
| lipid modification | GO:0030258 | 65 | 0.023 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.023 | |
| regulation of secretion | GO:0051046 | 274 | 0.023 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.022 | |
| regulation of hormone levels | GO:0010817 | 211 | 0.022 | |
| regulation of ossification | GO:0030278 | 112 | 0.022 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.021 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.021 | |
| visual behavior | GO:0007632 | 45 | 0.021 | |
| organic acid catabolic process | GO:0016054 | 51 | 0.021 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 167 | 0.021 | |
| homeostasis of number of cells | GO:0048872 | 210 | 0.021 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 58 | 0.021 | |
| response to starvation | GO:0042594 | 65 | 0.021 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.021 | |
| fatty acid oxidation | GO:0019395 | 28 | 0.021 | |
| positive regulation of secretion by cell | GO:1903532 | 114 | 0.021 | |
| very long chain fatty acid catabolic process | GO:0042760 | 2 | 0.020 | |
| peptidyl amino acid modification | GO:0018193 | 336 | 0.020 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.020 | |
| maintenance of location | GO:0051235 | 89 | 0.020 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.020 | |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.020 | |
| regulation of protein processing | GO:0070613 | 96 | 0.020 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.020 | |
| negative regulation of protein maturation | GO:1903318 | 79 | 0.019 | |
| glucan metabolic process | GO:0044042 | 32 | 0.019 | |
| regulation of mapk cascade | GO:0043408 | 248 | 0.019 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.019 | |
| regulation of vesicle mediated transport | GO:0060627 | 139 | 0.019 | |
| negative regulation of proteolysis | GO:0045861 | 74 | 0.019 | |
| carboxylic acid catabolic process | GO:0046395 | 51 | 0.019 | |
| retrograde transport endosome to golgi | GO:0042147 | 2 | 0.019 | |
| cellular response to cytokine stimulus | GO:0071345 | 189 | 0.018 | |
| regulation of body fluid levels | GO:0050878 | 162 | 0.018 | |
| cation transmembrane transport | GO:0098655 | 266 | 0.018 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.018 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.018 | |
| t cell activation | GO:0042110 | 289 | 0.018 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.018 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.018 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.018 | |
| endomembrane system organization | GO:0010256 | 147 | 0.018 | |
| regulation of dephosphorylation | GO:0035303 | 18 | 0.017 | |
| germ line stem cell division | GO:0042078 | 2 | 0.017 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 48 | 0.017 | |
| negative regulation of glycogen biosynthetic process | GO:0045719 | 1 | 0.017 | |
| regulation of transferase activity | GO:0051338 | 263 | 0.017 | |
| positive regulation of secretion | GO:0051047 | 130 | 0.017 | |
| sperm motility | GO:0030317 | 47 | 0.017 | |
| lipid biosynthetic process | GO:0008610 | 179 | 0.017 | |
| alpha amino acid metabolic process | GO:1901605 | 59 | 0.017 | |
| cellular response to oxidative stress | GO:0034599 | 76 | 0.017 | |
| immune effector process | GO:0002252 | 321 | 0.016 | |
| cellular carbohydrate metabolic process | GO:0044262 | 119 | 0.016 | |
| vacuole organization | GO:0007033 | 38 | 0.016 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.016 | |
| mitotic cytokinesis | GO:0000281 | 4 | 0.016 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.016 | |
| neuron death | GO:0070997 | 154 | 0.016 | |
| defense response to bacterium | GO:0042742 | 119 | 0.016 | |
| energy derivation by oxidation of organic compounds | GO:0015980 | 77 | 0.016 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.016 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.015 | |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.015 | |
| establishment of protein localization to peroxisome | GO:0072663 | 4 | 0.015 | |
| rab protein signal transduction | GO:0032482 | 1 | 0.015 | |
| negative regulation of cellular protein catabolic process | GO:1903363 | 22 | 0.015 | |
| regulation of osteoblast differentiation | GO:0045667 | 67 | 0.015 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.015 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.015 | |
| positive regulation of macroautophagy | GO:0016239 | 3 | 0.015 | |
| renal water transport | GO:0003097 | 6 | 0.015 | |
| negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway | GO:1902176 | 4 | 0.015 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.015 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 73 | 0.015 | |
| interspecies interaction between organisms | GO:0044419 | 83 | 0.015 | |
| mitochondrion organization | GO:0007005 | 134 | 0.014 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.014 | |
| divalent metal ion transport | GO:0070838 | 172 | 0.014 | |
| methylation | GO:0032259 | 134 | 0.014 | |
| extracellular structure organization | GO:0043062 | 148 | 0.014 | |
| response to endoplasmic reticulum stress | GO:0034976 | 53 | 0.014 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.014 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.014 | |
| negative regulation of proteolysis involved in cellular protein catabolic process | GO:1903051 | 22 | 0.014 | |
| response to light stimulus | GO:0009416 | 135 | 0.014 | |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.014 | |
| monoamine transport | GO:0015844 | 33 | 0.014 | |
| regulation of ion transport | GO:0043269 | 215 | 0.014 | |
| cellular metal ion homeostasis | GO:0006875 | 151 | 0.014 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.014 | |
| divalent inorganic cation transport | GO:0072511 | 178 | 0.013 | |
| negative regulation of cytokine production | GO:0001818 | 84 | 0.013 | |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.013 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 45 | 0.013 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.013 | |
| protein localization to organelle | GO:0033365 | 185 | 0.013 | |
| ear development | GO:0043583 | 200 | 0.013 | |
| negative regulation of cell cycle process | GO:0010948 | 69 | 0.013 | |
| dna recombination | GO:0006310 | 92 | 0.013 | |
| anatomical structure homeostasis | GO:0060249 | 145 | 0.013 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.013 | |
| response to oxygen levels | GO:0070482 | 62 | 0.013 | |
| phospholipid metabolic process | GO:0006644 | 87 | 0.012 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.012 | |
| carbohydrate homeostasis | GO:0033500 | 128 | 0.012 | |
| sequestering of metal ion | GO:0051238 | 19 | 0.012 | |
| protein secretion | GO:0009306 | 111 | 0.012 | |
| negative regulation of growth | GO:0045926 | 99 | 0.012 | |
| regulation of peptide transport | GO:0090087 | 91 | 0.012 | |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.012 | |
| organelle fission | GO:0048285 | 170 | 0.012 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.012 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.012 | |
| negative regulation of nervous system development | GO:0051961 | 156 | 0.012 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.012 | |
| digestive tract morphogenesis | GO:0048546 | 147 | 0.012 | |
| response to radiation | GO:0009314 | 165 | 0.012 | |
| biomineral tissue development | GO:0031214 | 64 | 0.012 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.012 | |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.012 | |
| g protein coupled receptor signaling pathway | GO:0007186 | 243 | 0.012 | |
| action potential | GO:0001508 | 78 | 0.012 | |
| microtubule based process | GO:0007017 | 236 | 0.012 | |
| protein kinase b signaling | GO:0043491 | 74 | 0.012 | |
| modification by host of symbiont morphology or physiology | GO:0051851 | 12 | 0.012 | |
| sensory perception | GO:0007600 | 245 | 0.011 | |
| divalent inorganic cation homeostasis | GO:0072507 | 138 | 0.011 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 143 | 0.011 | |
| substantia nigra development | GO:0021762 | 2 | 0.011 | |
| negative regulation of protein transport | GO:0051224 | 46 | 0.011 | |
| neuron apoptotic process | GO:0051402 | 142 | 0.011 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.011 | |
| cell division | GO:0051301 | 120 | 0.011 | |
| chemotaxis | GO:0006935 | 247 | 0.011 | |
| endocytosis | GO:0006897 | 168 | 0.011 | |
| mitochondrial dna metabolic process | GO:0032042 | 13 | 0.011 | |
| cation homeostasis | GO:0055080 | 212 | 0.011 | |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.011 | |
| cellular homeostasis | GO:0019725 | 240 | 0.011 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 192 | 0.011 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.011 | |
| vitamin d3 metabolic process | GO:0070640 | 3 | 0.011 | |
| lipid catabolic process | GO:0016042 | 69 | 0.011 | |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.011 | |
| negative regulation of organelle organization | GO:0010639 | 90 | 0.011 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.011 | |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 68 | 0.011 | |
| mapk cascade | GO:0000165 | 281 | 0.011 | |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.011 | |
| cellular glucose homeostasis | GO:0001678 | 52 | 0.011 | |
| skin development | GO:0043588 | 220 | 0.011 | |
| sensory perception of pain | GO:0019233 | 47 | 0.011 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.011 | |
| rhythmic process | GO:0048511 | 174 | 0.011 | |
| regulation of biomineral tissue development | GO:0070167 | 33 | 0.010 | |
| response to growth factor | GO:0070848 | 198 | 0.010 | |
| negative regulation of mitochondrion organization | GO:0010823 | 9 | 0.010 | |
| positive regulation of mitochondrial fission | GO:0090141 | 2 | 0.010 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.010 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.010 | |
| hormone secretion | GO:0046879 | 128 | 0.010 | |
| insulin secretion involved in cellular response to glucose stimulus | GO:0035773 | 36 | 0.010 | |
| multicellular organismal signaling | GO:0035637 | 91 | 0.010 | |
| isoprenoid metabolic process | GO:0006720 | 29 | 0.010 | |
| response to molecule of bacterial origin | GO:0002237 | 143 | 0.010 | |
| sterol homeostasis | GO:0055092 | 45 | 0.010 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 126 | 0.010 | |
| calcium ion homeostasis | GO:0055074 | 127 | 0.010 | |
| regulation of protein binding | GO:0043393 | 60 | 0.010 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.010 | |
| cellular response to organic cyclic compound | GO:0071407 | 87 | 0.010 | |
| innate immune response | GO:0045087 | 157 | 0.010 | |
| muscle tissue development | GO:0060537 | 308 | 0.010 | |
| cytokine production | GO:0001816 | 319 | 0.010 | |
| reactive oxygen species biosynthetic process | GO:1903409 | 8 | 0.010 | |
