| oocyte axis specification | GO:0007309 | 2 | 0.983 | Fly |
| establishment or maintenance of microtubule cytoskeleton polarity | GO:0030951 | 1 | 0.888 | Fly |
| oocyte construction | GO:0007308 | 2 | 0.884 | Fly |
| regulation of epidermal cell division | GO:0010482 | 3 | 0.882 | Mouse |
| inclusion body assembly | GO:0070841 | 3 | 0.839 | Yeast |
| thermosensory behavior | GO:0040040 | 1 | 0.809 | Fly |
| protein targeting | GO:0006605 | 143 | 0.805 | |
| nucleoside phosphate catabolic process | GO:1901292 | 222 | 0.801 | |
| intracellular protein transport | GO:0006886 | 204 | 0.788 | |
| organonitrogen compound catabolic process | GO:1901565 | 264 | 0.768 | |
| organic cyclic compound catabolic process | GO:1901361 | 295 | 0.747 | |
| nucleotide catabolic process | GO:0009166 | 217 | 0.746 | |
| cellular response to dna damage stimulus | GO:0006974 | 207 | 0.735 | Yeast |
| negative regulation of cellular component organization | GO:0051129 | 194 | 0.721 | Yeast |
| purine ribonucleotide catabolic process | GO:0009154 | 208 | 0.721 | |
| small gtpase mediated signal transduction | GO:0007264 | 97 | 0.704 | Yeast Mouse Fly |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 226 | 0.700 | |
| response to organonitrogen compound | GO:0010243 | 246 | 0.686 | |
| nucleotide metabolic process | GO:0009117 | 332 | 0.682 | |
| ribonucleotide catabolic process | GO:0009261 | 208 | 0.673 | |
| ras protein signal transduction | GO:0007265 | 77 | 0.652 | Yeast Fly |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 199 | 0.651 | |
| organophosphate catabolic process | GO:0046434 | 232 | 0.645 | |
| negative regulation of protein dephosphorylation | GO:0035308 | 2 | 0.631 | Mouse |
| keratinocyte development | GO:0003334 | 10 | 0.630 | Mouse |
| germ cell development | GO:0007281 | 185 | 0.606 | Fly |
| carbohydrate derivative catabolic process | GO:1901136 | 231 | 0.602 | |
| glycosyl compound catabolic process | GO:1901658 | 206 | 0.599 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 199 | 0.575 | |
| nucleoside catabolic process | GO:0009164 | 206 | 0.575 | |
| heterocycle catabolic process | GO:0046700 | 280 | 0.571 | |
| pole plasm assembly | GO:0007315 | 2 | 0.570 | |
| purine ribonucleoside catabolic process | GO:0046130 | 205 | 0.566 | |
| regulation of ras protein signal transduction | GO:0046578 | 114 | 0.557 | Fly |
| nucleoside phosphate metabolic process | GO:0006753 | 338 | 0.548 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 230 | 0.541 | |
| cellular response to organonitrogen compound | GO:0071417 | 145 | 0.523 | |
| establishment of protein localization to organelle | GO:0072594 | 118 | 0.520 | |
| gtp catabolic process | GO:0006184 | 143 | 0.519 | |
| positive regulation of mapk cascade | GO:0043410 | 170 | 0.511 | Fly |
| regulation of cellular catabolic process | GO:0031329 | 242 | 0.510 | |
| purine ribonucleotide metabolic process | GO:0009150 | 290 | 0.506 | |
| mitochondrion organization | GO:0007005 | 134 | 0.499 | |
| developmental maturation | GO:0021700 | 193 | 0.492 | Fly |
| autophagy | GO:0006914 | 45 | 0.492 | |
| single organism nuclear import | GO:1902593 | 95 | 0.491 | |
| cellular response to insulin stimulus | GO:0032869 | 78 | 0.489 | |
| regulation of intracellular transport | GO:0032386 | 159 | 0.489 | Mouse |
| mitotic cell cycle | GO:0000278 | 195 | 0.487 | Yeast Worm Fly |
| negative regulation of protein metabolic process | GO:0051248 | 282 | 0.482 | Yeast Mouse |
| cellular nitrogen compound catabolic process | GO:0044270 | 280 | 0.478 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 247 | 0.473 | |
| nuclear transport | GO:0051169 | 139 | 0.471 | Mouse |
| ribonucleoside catabolic process | GO:0042454 | 206 | 0.468 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 147 | 0.463 | |
| cell division | GO:0051301 | 120 | 0.462 | Yeast Mouse Worm |
| purine nucleotide catabolic process | GO:0006195 | 211 | 0.460 | |
| oocyte anterior posterior axis specification | GO:0007314 | 2 | 0.447 | |
| purine nucleoside metabolic process | GO:0042278 | 241 | 0.432 | |
| ribonucleoside metabolic process | GO:0009119 | 245 | 0.432 | |
| guanosine containing compound metabolic process | GO:1901068 | 144 | 0.431 | |
| negative regulation of phosphate metabolic process | GO:0045936 | 184 | 0.426 | Mouse |
| regulation of cell cycle | GO:0051726 | 281 | 0.425 | Yeast Mouse Worm |
| establishment of vesicle localization | GO:0051650 | 81 | 0.410 | |
| mapk cascade | GO:0000165 | 281 | 0.405 | Fly |
| synaptic transmission | GO:0007268 | 329 | 0.396 | Human |
| ribonucleotide metabolic process | GO:0009259 | 291 | 0.393 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 157 | 0.391 | Mouse |
| purine containing compound catabolic process | GO:0072523 | 213 | 0.388 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 66 | 0.387 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 203 | 0.387 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 220 | 0.384 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 205 | 0.381 | |
| regulation of protein export from nucleus | GO:0046825 | 11 | 0.347 | Mouse |
| positive regulation of protein export from nucleus | GO:0046827 | 4 | 0.345 | Mouse |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 220 | 0.345 | |
| regulation of exit from mitosis | GO:0007096 | 1 | 0.344 | Yeast |
| oocyte differentiation | GO:0009994 | 35 | 0.343 | Fly |
| protein heterooligomerization | GO:0051291 | 14 | 0.339 | |
| protein localization to organelle | GO:0033365 | 185 | 0.339 | |
| purine nucleoside catabolic process | GO:0006152 | 205 | 0.336 | |
| response to oxidative stress | GO:0006979 | 123 | 0.335 | |
| cytoplasmic transport | GO:0016482 | 234 | 0.334 | Mouse |
| protein modification by small protein conjugation or removal | GO:0070647 | 207 | 0.333 | Yeast |
| aromatic compound catabolic process | GO:0019439 | 286 | 0.333 | |
| negative regulation of transferase activity | GO:0051348 | 85 | 0.333 | Yeast |
| protein catabolic process | GO:0030163 | 221 | 0.333 | |
| telencephalon development | GO:0021537 | 186 | 0.331 | Mouse |
| cation transport | GO:0006812 | 399 | 0.329 | |
| negative regulation of peroxidase activity | GO:2000469 | 1 | 0.325 | |
| regionalization | GO:0003002 | 337 | 0.325 | Worm |
| zygote asymmetric cell division | GO:0010070 | 2 | 0.324 | Worm |
| microtubule based process | GO:0007017 | 236 | 0.323 | Worm Fly |
| cellular ketone metabolic process | GO:0042180 | 84 | 0.322 | |
| protein modification by small protein conjugation | GO:0032446 | 187 | 0.322 | Yeast |
| regulation of cellular response to stress | GO:0080135 | 159 | 0.312 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 352 | 0.310 | |
| regulation of protein localization | GO:0032880 | 231 | 0.308 | Mouse |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 40 | 0.308 | |
| aggresome assembly | GO:0070842 | 2 | 0.307 | Yeast |
| regulation of protein kinase activity | GO:0045859 | 232 | 0.305 | Mouse |
| purine ribonucleoside metabolic process | GO:0046128 | 241 | 0.305 | |
| cellular protein catabolic process | GO:0044257 | 155 | 0.304 | |
| regulation of protein transport | GO:0051223 | 163 | 0.303 | Mouse |
| regulation of mapk cascade | GO:0043408 | 248 | 0.302 | Fly |
| positive regulation of erk1 and erk2 cascade | GO:0070374 | 47 | 0.297 | Fly |
| negative regulation of ubiquitin protein transferase activity | GO:0051444 | 3 | 0.297 | Yeast |
| female gamete generation | GO:0007292 | 74 | 0.294 | Fly |
| vesicle localization | GO:0051648 | 86 | 0.294 | |
| establishment of organelle localization | GO:0051656 | 122 | 0.292 | Worm |
| regulation of intracellular protein transport | GO:0033157 | 82 | 0.287 | Mouse |
| regulation of synaptic vesicle transport | GO:1902803 | 13 | 0.280 | |
| fertilization | GO:0009566 | 127 | 0.277 | Worm |
| positive regulation of protein kinase activity | GO:0045860 | 144 | 0.276 | |
| regulation of proteolysis | GO:0030162 | 164 | 0.276 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 184 | 0.273 | Mouse |
| guanosine containing compound catabolic process | GO:1901069 | 144 | 0.272 | |
| purine nucleotide metabolic process | GO:0006163 | 302 | 0.271 | |
| cell fate commitment | GO:0045165 | 210 | 0.267 | Worm Fly |
| mitochondrion distribution | GO:0048311 | 4 | 0.257 | |
| monocarboxylic acid metabolic process | GO:0032787 | 191 | 0.255 | |
| glycosyl compound metabolic process | GO:1901657 | 246 | 0.253 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 247 | 0.252 | Yeast Mouse |
| regulation of mitochondrion organization | GO:0010821 | 27 | 0.250 | |
| oxidation reduction process | GO:0055114 | 342 | 0.246 | Yeast |
| neurotransmitter secretion | GO:0007269 | 62 | 0.243 | |
| muscle cell differentiation | GO:0042692 | 261 | 0.236 | |
| regulation of protein stability | GO:0031647 | 52 | 0.234 | Fly |
| oogenesis | GO:0048477 | 56 | 0.234 | Fly |
| positive regulation of protein transport | GO:0051222 | 93 | 0.230 | Mouse |
| establishment of mitochondrion localization | GO:0051654 | 4 | 0.220 | |
| regulation of synaptic growth at neuromuscular junction | GO:0008582 | 4 | 0.218 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 56 | 0.217 | |
| membrane organization | GO:0061024 | 245 | 0.216 | |
| spermatogenesis | GO:0007283 | 284 | 0.215 | |
| regulation of neuron projection development | GO:0010975 | 169 | 0.213 | |
| regulation of ubiquitin protein ligase activity involved in mitotic cell cycle | GO:0051439 | 1 | 0.212 | Yeast |
| meiotic nuclear division | GO:0007126 | 115 | 0.211 | Worm |
| ribose phosphate metabolic process | GO:0019693 | 291 | 0.207 | |
| neurotransmitter transport | GO:0006836 | 76 | 0.206 | |
| gtp metabolic process | GO:0046039 | 144 | 0.195 | |
| epidermal cell division | GO:0010481 | 3 | 0.192 | Mouse |
| regulation of cell morphogenesis involved in differentiation | GO:0010769 | 151 | 0.188 | |
| response to organic cyclic compound | GO:0014070 | 198 | 0.186 | |
| regulation of neuron death | GO:1901214 | 134 | 0.185 | |
| protein localization to plasma membrane | GO:0072659 | 57 | 0.185 | |
| striated muscle myosin thick filament assembly | GO:0071688 | 1 | 0.184 | |
| regulation of cell projection organization | GO:0031344 | 206 | 0.184 | |
| microtubule cytoskeleton organization | GO:0000226 | 157 | 0.183 | Worm Fly |
| purine containing compound metabolic process | GO:0072521 | 311 | 0.182 | |
| response to light stimulus | GO:0009416 | 135 | 0.181 | |
| regulation of cellular protein catabolic process | GO:1903362 | 61 | 0.181 | |
| potassium ion transport | GO:0006813 | 52 | 0.181 | |
| regulation of vesicle mediated transport | GO:0060627 | 139 | 0.180 | |
| positive regulation of growth | GO:0045927 | 104 | 0.179 | Mouse |
| positive regulation of ras protein signal transduction | GO:0046579 | 13 | 0.175 | Fly |
| regulation of cytoplasmic transport | GO:1903649 | 112 | 0.175 | Mouse |
| fatty acid metabolic process | GO:0006631 | 121 | 0.174 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.174 | |
| regulation of nucleotide metabolic process | GO:0006140 | 169 | 0.173 | |
| monosaccharide metabolic process | GO:0005996 | 106 | 0.172 | |
| establishment of protein localization to membrane | GO:0090150 | 54 | 0.172 | |
| synaptic vesicle localization | GO:0097479 | 59 | 0.172 | |
| lipid biosynthetic process | GO:0008610 | 179 | 0.172 | |
| establishment or maintenance of cytoskeleton polarity | GO:0030952 | 2 | 0.172 | Fly |
| microtubule based movement | GO:0007018 | 84 | 0.167 | |
| regulation of gtp catabolic process | GO:0033124 | 113 | 0.167 | |
| locomotory behavior | GO:0007626 | 195 | 0.166 | |
| macromolecule catabolic process | GO:0009057 | 281 | 0.165 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 5 | 0.164 | |
| regulation of epithelial cell proliferation | GO:0050678 | 141 | 0.163 | Mouse |
| positive regulation of cellular amine metabolic process | GO:0033240 | 5 | 0.163 | |
| rac protein signal transduction | GO:0016601 | 13 | 0.163 | |
| glycerolipid biosynthetic process | GO:0045017 | 50 | 0.161 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 122 | 0.161 | |
| negative regulation of protein modification process | GO:0031400 | 163 | 0.161 | Yeast Mouse |
| negative regulation of phosphorylation | GO:0042326 | 166 | 0.161 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 88 | 0.161 | |
| regulation of hydrolase activity | GO:0051336 | 246 | 0.160 | |
| male gamete generation | GO:0048232 | 285 | 0.160 | |
| regulation of neurotransmitter levels | GO:0001505 | 87 | 0.160 | |
| negative regulation of ligase activity | GO:0051352 | 3 | 0.159 | Yeast |
| cell adhesion | GO:0007155 | 329 | 0.159 | |
| cellular macromolecule catabolic process | GO:0044265 | 206 | 0.159 | |
| glucan metabolic process | GO:0044042 | 32 | 0.158 | Yeast |
| epithelial cell development | GO:0002064 | 159 | 0.158 | Mouse |
| protein targeting to mitochondrion | GO:0006626 | 6 | 0.158 | |
| mitotic cell cycle process | GO:1903047 | 159 | 0.158 | Yeast Worm |
| regulation of synaptic plasticity | GO:0048167 | 87 | 0.154 | Human |
| regulation of protein complex assembly | GO:0043254 | 83 | 0.153 | |
| hippocampus development | GO:0021766 | 52 | 0.152 | Mouse |
| establishment of synaptic vesicle localization | GO:0097480 | 57 | 0.152 | |
| pallium development | GO:0021543 | 120 | 0.151 | Mouse |
| regulation of protein targeting | GO:1903533 | 61 | 0.151 | |
| dendritic spine organization | GO:0097061 | 26 | 0.149 | |
| regulation of organelle organization | GO:0033043 | 289 | 0.149 | Yeast |
| leukocyte proliferation | GO:0070661 | 172 | 0.148 | |
| carbohydrate metabolic process | GO:0005975 | 230 | 0.147 | Yeast |
| axon cargo transport | GO:0008088 | 33 | 0.147 | |
| establishment or maintenance of cell polarity | GO:0007163 | 86 | 0.146 | Worm Fly |
| nucleoside metabolic process | GO:0009116 | 246 | 0.146 | |
| dephosphorylation | GO:0016311 | 129 | 0.146 | Mouse |
| cellular amino acid metabolic process | GO:0006520 | 103 | 0.144 | |
| protein stabilization | GO:0050821 | 25 | 0.144 | Fly |
| regulation of actin cytoskeleton organization | GO:0032956 | 84 | 0.143 | |
| regulation of cytoskeleton organization | GO:0051493 | 122 | 0.142 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 132 | 0.142 | |
| lateral inhibition | GO:0046331 | 1 | 0.141 | |
| regulation of ion transport | GO:0043269 | 215 | 0.140 | |
| axonogenesis | GO:0007409 | 274 | 0.139 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 169 | 0.138 | |
| negative regulation of molecular function | GO:0044092 | 258 | 0.137 | Yeast |
| protein oligomerization | GO:0051259 | 67 | 0.137 | |
| cognition | GO:0050890 | 149 | 0.137 | Fly |
| dendrite development | GO:0016358 | 115 | 0.137 | |
| chemotaxis | GO:0006935 | 247 | 0.137 | |
| hemostasis | GO:0007599 | 78 | 0.134 | |
| positive regulation of cytoplasmic transport | GO:1903651 | 40 | 0.134 | Mouse |
| regulation of cell growth | GO:0001558 | 91 | 0.133 | Mouse |
| positive regulation of intracellular protein transport | GO:0090316 | 42 | 0.132 | Mouse |
| cellular amine metabolic process | GO:0044106 | 44 | 0.130 | |
| limbic system development | GO:0021761 | 72 | 0.129 | Mouse |
| polysaccharide metabolic process | GO:0005976 | 39 | 0.128 | Yeast |
| intracellular mrna localization | GO:0008298 | 4 | 0.128 | |
| protein import into nucleus | GO:0006606 | 95 | 0.128 | |
| regulation of protein catabolic process | GO:0042176 | 108 | 0.128 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 46 | 0.128 | |
| positive regulation of protein phosphorylation | GO:0001934 | 242 | 0.127 | |
| cytoskeleton dependent intracellular transport | GO:0030705 | 50 | 0.125 | |
| regulation of cell cycle process | GO:0010564 | 160 | 0.124 | Yeast |
| terminal button organization | GO:0072553 | 3 | 0.122 | |
| cell growth | GO:0016049 | 130 | 0.121 | Yeast Mouse |
| intracellular distribution of mitochondria | GO:0048312 | 1 | 0.121 | |
| regulation of cellular component size | GO:0032535 | 121 | 0.120 | |
| dna metabolic process | GO:0006259 | 303 | 0.120 | Yeast |
| single fertilization | GO:0007338 | 82 | 0.119 | Worm |
| regulation of actin filament length | GO:0030832 | 45 | 0.118 | |
| neuron apoptotic process | GO:0051402 | 142 | 0.118 | |
| endocytosis | GO:0006897 | 168 | 0.118 | Worm |
| cellular response to peptide hormone stimulus | GO:0071375 | 92 | 0.117 | |
| cellular lipid metabolic process | GO:0044255 | 323 | 0.117 | |
| regulation of ras gtpase activity | GO:0032318 | 88 | 0.116 | |
| cofactor metabolic process | GO:0051186 | 80 | 0.116 | |
| response to radiation | GO:0009314 | 165 | 0.115 | |
| proteasomal protein catabolic process | GO:0010498 | 98 | 0.114 | |
| regulation of neuron apoptotic process | GO:0043523 | 122 | 0.113 | |
| regulation of secretion by cell | GO:1903530 | 249 | 0.113 | |
| response to insulin | GO:0032868 | 100 | 0.112 | |
| actin polymerization or depolymerization | GO:0008154 | 54 | 0.112 | |
| regulation of ion transmembrane transport | GO:0034765 | 119 | 0.111 | |
| keratinocyte differentiation | GO:0030216 | 48 | 0.111 | Mouse |
| nucleocytoplasmic transport | GO:0006913 | 139 | 0.111 | Mouse |
| response to ammonium ion | GO:0060359 | 21 | 0.109 | |
| multicellular organism growth | GO:0035264 | 161 | 0.109 | |
| regulation of dephosphorylation | GO:0035303 | 18 | 0.108 | Mouse |
| rho protein signal transduction | GO:0007266 | 32 | 0.107 | |
| negative regulation of organelle organization | GO:0010639 | 90 | 0.106 | Yeast |
| regulation of ubiquitin protein transferase activity | GO:0051438 | 7 | 0.106 | Yeast |
| gluconeogenesis | GO:0006094 | 39 | 0.105 | |
| mitochondrial transport | GO:0006839 | 36 | 0.105 | |
| chromosome segregation | GO:0007059 | 48 | 0.105 | Fly |
| positive regulation of apoptotic process | GO:0043065 | 217 | 0.103 | |
| oocyte development | GO:0048599 | 33 | 0.103 | Fly |
| positive regulation of gtp catabolic process | GO:0033126 | 85 | 0.102 | |
| regulation of erk1 and erk2 cascade | GO:0070372 | 71 | 0.102 | Fly |
| inorganic cation transmembrane transport | GO:0098662 | 207 | 0.101 | |
| regulation of epidermal cell differentiation | GO:0045604 | 21 | 0.101 | Mouse |
| cerebral cortex development | GO:0021987 | 86 | 0.101 | Mouse |
| amine metabolic process | GO:0009308 | 45 | 0.101 | |
| activation of mapkk activity | GO:0000186 | 15 | 0.101 | |
| atp metabolic process | GO:0046034 | 75 | 0.100 | |
| organelle fission | GO:0048285 | 170 | 0.100 | Yeast Worm |
| regulation of cell adhesion | GO:0030155 | 154 | 0.100 | |
| response to nutrient levels | GO:0031667 | 109 | 0.099 | |
| synapse organization | GO:0050808 | 125 | 0.099 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 45 | 0.099 | Yeast |
| learning | GO:0007612 | 98 | 0.099 | |
| response to peptide hormone | GO:0043434 | 127 | 0.099 | |
| cellular response to hormone stimulus | GO:0032870 | 150 | 0.098 | |
| olfactory learning | GO:0008355 | 2 | 0.098 | |
| calcium ion homeostasis | GO:0055074 | 127 | 0.097 | |
| neural precursor cell proliferation | GO:0061351 | 121 | 0.097 | |
| regulation of nucleoside metabolic process | GO:0009118 | 130 | 0.096 | |
| regulation of mitotic cell cycle | GO:0007346 | 126 | 0.096 | Yeast Worm |
| modification dependent protein catabolic process | GO:0019941 | 133 | 0.096 | |
| positive regulation of synaptic growth at neuromuscular junction | GO:0045887 | 1 | 0.095 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 91 | 0.095 | |
| regulation of cellular component biogenesis | GO:0044087 | 181 | 0.095 | |
| dna integrity checkpoint | GO:0031570 | 28 | 0.095 | Yeast |
| multicellular organismal aging | GO:0010259 | 24 | 0.094 | Worm |
| energy reserve metabolic process | GO:0006112 | 39 | 0.094 | Yeast |
| positive regulation of cell development | GO:0010720 | 237 | 0.094 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 133 | 0.093 | |
| asymmetric neuroblast division | GO:0055059 | 1 | 0.092 | |
| spindle localization | GO:0051653 | 22 | 0.092 | Worm |
| phagocytosis | GO:0006909 | 66 | 0.091 | |
| nuclear import | GO:0051170 | 95 | 0.091 | |
| cell type specific apoptotic process | GO:0097285 | 268 | 0.091 | |
| cellular response to organic cyclic compound | GO:0071407 | 87 | 0.090 | |
| nucleoside monophosphate catabolic process | GO:0009125 | 59 | 0.090 | |
| regulation of secretion | GO:0051046 | 274 | 0.089 | |
| intermediate filament based process | GO:0045103 | 27 | 0.089 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 155 | 0.089 | Fly |
| positive regulation of transferase activity | GO:0051347 | 167 | 0.089 | |
| inorganic ion transmembrane transport | GO:0098660 | 234 | 0.089 | |
| regulation of membrane potential | GO:0042391 | 192 | 0.086 | |
| positive regulation of neuron projection development | GO:0010976 | 79 | 0.085 | |
| negative regulation of mitochondrion organization | GO:0010823 | 9 | 0.085 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 0 | 0.085 | |
| regulation of transposition | GO:0010528 | 2 | 0.085 | |
| protein localization to nucleus | GO:0034504 | 121 | 0.085 | |
| response to peptide | GO:1901652 | 136 | 0.084 | |
| single organism cell adhesion | GO:0098602 | 156 | 0.083 | |
| protein ubiquitination | GO:0016567 | 171 | 0.082 | Yeast |
| action potential | GO:0001508 | 78 | 0.082 | |
| apoptotic signaling pathway | GO:0097190 | 306 | 0.082 | |
| maternal determination of anterior posterior axis embryo | GO:0008358 | 2 | 0.081 | |
| negative regulation of cell cycle | GO:0045786 | 123 | 0.081 | Yeast |
| protein export from nucleus | GO:0006611 | 20 | 0.081 | Mouse |
| positive regulation of nervous system development | GO:0051962 | 221 | 0.080 | |
| cellular response to oxidative stress | GO:0034599 | 76 | 0.079 | |
| positive regulation of protein modification process | GO:0031401 | 299 | 0.079 | |
| organelle localization | GO:0051640 | 179 | 0.079 | Worm |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 57 | 0.079 | Yeast |
| regulation of neuron differentiation | GO:0045664 | 281 | 0.078 | Human |
| positive regulation of programmed cell death | GO:0043068 | 218 | 0.078 | |
| cellular carbohydrate metabolic process | GO:0044262 | 119 | 0.078 | Yeast |
| cell maturation | GO:0048469 | 127 | 0.077 | Fly |
| positive regulation of ras gtpase activity | GO:0032320 | 65 | 0.077 | |
| regulation of autophagy | GO:0010506 | 30 | 0.077 | |
| positive regulation of cell growth | GO:0030307 | 33 | 0.077 | Mouse |
| neuron projection guidance | GO:0097485 | 141 | 0.077 | |
| regulation of terminal button organization | GO:2000331 | 1 | 0.077 | |
| telencephalon cell migration | GO:0022029 | 55 | 0.076 | |
| cellular ion homeostasis | GO:0006873 | 165 | 0.076 | |
| cell fate specification | GO:0001708 | 72 | 0.076 | Worm |
| protein localization to membrane | GO:0072657 | 108 | 0.076 | |
| gonad development | GO:0008406 | 141 | 0.076 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 114 | 0.075 | |
| single organismal cell cell adhesion | GO:0016337 | 131 | 0.075 | |
| negative regulation of cell cycle process | GO:0010948 | 69 | 0.075 | Yeast |
| negative regulation of protein phosphorylation | GO:0001933 | 126 | 0.075 | |
| positive regulation of cellular catabolic process | GO:0031331 | 148 | 0.074 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 94 | 0.074 | |
| regulation of kinase activity | GO:0043549 | 249 | 0.073 | Mouse |
| hexose metabolic process | GO:0019318 | 98 | 0.073 | |
| regulation of membrane depolarization | GO:0003254 | 11 | 0.073 | |
| dna damage checkpoint | GO:0000077 | 26 | 0.073 | Yeast |
| actin filament organization | GO:0007015 | 113 | 0.073 | |
| negative regulation of nuclear division | GO:0051784 | 19 | 0.073 | Yeast |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 73 | 0.072 | Yeast |
| regulation of anatomical structure size | GO:0090066 | 178 | 0.071 | |
| lymphocyte proliferation | GO:0046651 | 164 | 0.071 | |
| stem cell proliferation | GO:0072089 | 117 | 0.071 | |
| atp catabolic process | GO:0006200 | 55 | 0.071 | |
| glucose metabolic process | GO:0006006 | 92 | 0.071 | |
| response to metal ion | GO:0010038 | 47 | 0.070 | |
| positive regulation of proteolysis | GO:0045862 | 85 | 0.070 | |
| peptidyl serine modification | GO:0018209 | 83 | 0.069 | |
| negative regulation of hydrolase activity | GO:0051346 | 71 | 0.069 | |
| regulation of synaptic vesicle exocytosis | GO:2000300 | 11 | 0.068 | |
| positive regulation of nucleocytoplasmic transport | GO:0046824 | 30 | 0.068 | Mouse |
| regulation of nucleotide catabolic process | GO:0030811 | 122 | 0.067 | |
| regulation of neurotransmitter transport | GO:0051588 | 35 | 0.067 | |
| response to hypoxia | GO:0001666 | 58 | 0.067 | |
| cellular protein complex assembly | GO:0043623 | 116 | 0.067 | |
| regulation of actin filament based process | GO:0032970 | 99 | 0.067 | |
| protein import | GO:0017038 | 101 | 0.067 | |
| regulation of neurotransmitter secretion | GO:0046928 | 29 | 0.067 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 61 | 0.067 | |
| regulation of peroxidase activity | GO:2000468 | 1 | 0.066 | |
| positive regulation of autophagy | GO:0010508 | 9 | 0.066 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 1 | 0.066 | |
| response to inorganic substance | GO:0010035 | 96 | 0.065 | |
| cellular polysaccharide metabolic process | GO:0044264 | 38 | 0.065 | Yeast |
| positive regulation of neuron differentiation | GO:0045666 | 141 | 0.065 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 88 | 0.065 | |
| coagulation | GO:0050817 | 78 | 0.064 | |
| axon guidance | GO:0007411 | 141 | 0.064 | |
| regulation of mitosis | GO:0007088 | 29 | 0.064 | Yeast |
| muscle cell development | GO:0055001 | 133 | 0.064 | |
| neuron death | GO:0070997 | 154 | 0.064 | |
| organism emergence from protective structure | GO:0071684 | 4 | 0.064 | Worm |
| positive regulation of nucleotide catabolic process | GO:0030813 | 88 | 0.064 | |
| synapse assembly | GO:0007416 | 56 | 0.063 | |
| cellular response to peptide | GO:1901653 | 92 | 0.063 | |
| meiotic cell cycle | GO:0051321 | 122 | 0.063 | Yeast Worm |
| cell fate determination | GO:0001709 | 32 | 0.063 | Worm Fly |
| negative regulation of keratinocyte proliferation | GO:0010839 | 7 | 0.063 | Mouse |
| regulation of rho gtpase activity | GO:0032319 | 58 | 0.063 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 129 | 0.062 | |
| macroautophagy | GO:0016236 | 21 | 0.062 | |
| myosin filament organization | GO:0031033 | 3 | 0.062 | |
| protein localization to mitochondrion | GO:0070585 | 15 | 0.062 | |
| regulation of stress activated mapk cascade | GO:0032872 | 69 | 0.062 | |
| negative regulation of intracellular transport | GO:0032387 | 38 | 0.061 | |
| olfactory bulb development | GO:0021772 | 30 | 0.061 | |
| spermatid differentiation | GO:0048515 | 115 | 0.061 | |
| regulation of organ growth | GO:0046620 | 61 | 0.060 | |
| regulation of endocytosis | GO:0030100 | 69 | 0.060 | |
| establishment of melanosome localization | GO:0032401 | 11 | 0.059 | |
| divalent inorganic cation homeostasis | GO:0072507 | 138 | 0.059 | |
| organelle disassembly | GO:1903008 | 2 | 0.058 | |
| dendritic spine development | GO:0060996 | 30 | 0.058 | |
| myosin filament assembly | GO:0031034 | 2 | 0.058 | |
| regulation of transmembrane transport | GO:0034762 | 128 | 0.058 | |
| transmission of nerve impulse | GO:0019226 | 76 | 0.058 | |
| cellular response to monoamine stimulus | GO:0071868 | 3 | 0.058 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 106 | 0.057 | |
| regulation of metal ion transport | GO:0010959 | 106 | 0.057 | |
| cellular chemical homeostasis | GO:0055082 | 215 | 0.057 | |
| mitotic cytokinesis | GO:0000281 | 4 | 0.057 | |
| regulation of cellular amine metabolic process | GO:0033238 | 20 | 0.057 | |
| erk1 and erk2 cascade | GO:0070371 | 77 | 0.057 | Fly |
| regulation of cellular response to oxidative stress | GO:1900407 | 19 | 0.057 | |
| mitotic spindle checkpoint | GO:0071174 | 9 | 0.057 | Yeast |
| cellular response to ammonium ion | GO:0071242 | 2 | 0.056 | |
| establishment of protein localization to mitochondrion | GO:0072655 | 11 | 0.056 | |
| positive regulation of cell death | GO:0010942 | 224 | 0.056 | |
| positive regulation of kinase activity | GO:0033674 | 155 | 0.056 | |
| regulation of protein ubiquitination | GO:0031396 | 52 | 0.056 | Yeast |
| regulation of protein maturation | GO:1903317 | 96 | 0.055 | |
| organic acid transport | GO:0015849 | 101 | 0.055 | |
| forebrain cell migration | GO:0021885 | 58 | 0.055 | |
| synaptic vesicle transport | GO:0048489 | 57 | 0.055 | |
| positive regulation of epidermal cell differentiation | GO:0045606 | 6 | 0.055 | Mouse |
| membrane fusion | GO:0061025 | 38 | 0.055 | |
| phospholipid biosynthetic process | GO:0008654 | 36 | 0.055 | |
| actin filament polymerization | GO:0030041 | 44 | 0.054 | |
| negative regulation of nucleoside metabolic process | GO:0045978 | 11 | 0.054 | |
| cation homeostasis | GO:0055080 | 212 | 0.054 | |
| transmembrane transport | GO:0055085 | 412 | 0.054 | |
| regulation of protein dephosphorylation | GO:0035304 | 4 | 0.053 | Mouse |
| ion transmembrane transport | GO:0034220 | 361 | 0.053 | |
| negative regulation of purine nucleotide catabolic process | GO:0033122 | 9 | 0.053 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 73 | 0.052 | Mouse |
| striated muscle tissue development | GO:0014706 | 293 | 0.052 | |
| hexose biosynthetic process | GO:0019319 | 39 | 0.052 | |
| mitochondrion localization | GO:0051646 | 9 | 0.052 | |
| positive regulation of protein catabolic process | GO:0045732 | 60 | 0.052 | |
| centrosome separation | GO:0051299 | 4 | 0.052 | |
| organ growth | GO:0035265 | 117 | 0.052 | |
| regulation of peptidase activity | GO:0052547 | 96 | 0.052 | |
| regulation of establishment of protein localization | GO:0070201 | 181 | 0.051 | Mouse |
| regulation of transporter activity | GO:0032409 | 57 | 0.051 | |
| calcium ion transport | GO:0006816 | 159 | 0.051 | |
| regulation of dendritic spine development | GO:0060998 | 22 | 0.051 | |
| actin cytoskeleton organization | GO:0030036 | 220 | 0.051 | |
| negative regulation of map kinase activity | GO:0043407 | 34 | 0.051 | |
| reactive oxygen species metabolic process | GO:0072593 | 84 | 0.051 | |
| organelle fusion | GO:0048284 | 28 | 0.051 | |
| bone resorption | GO:0045453 | 38 | 0.050 | |
| positive regulation of hydrolase activity | GO:0051345 | 148 | 0.050 | |
| myotube differentiation | GO:0014902 | 105 | 0.050 | |
| regulation of protein localization to nucleus | GO:1900180 | 60 | 0.050 | |
| developmental cell growth | GO:0048588 | 84 | 0.050 | |
| protein refolding | GO:0042026 | 1 | 0.049 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 104 | 0.049 | |
| negative regulation of cell proliferation | GO:0008285 | 296 | 0.049 | Mouse |
| intermediate filament cytoskeleton organization | GO:0045104 | 26 | 0.049 | |
| microtubule based transport | GO:0010970 | 50 | 0.049 | |
| regulation of dendritic spine morphogenesis | GO:0061001 | 17 | 0.049 | |
| metal ion homeostasis | GO:0055065 | 189 | 0.049 | |
| response to decreased oxygen levels | GO:0036293 | 59 | 0.048 | |
| regulation of cell division | GO:0051302 | 76 | 0.048 | Yeast Mouse |
| olfactory lobe development | GO:0021988 | 32 | 0.048 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 197 | 0.048 | |
| carbohydrate biosynthetic process | GO:0016051 | 74 | 0.048 | Yeast |
| positive regulation of cytoskeleton organization | GO:0051495 | 49 | 0.047 | |
| negative regulation of cellular response to insulin stimulus | GO:1900077 | 16 | 0.047 | |
| epithelial cell proliferation | GO:0050673 | 174 | 0.047 | Mouse |
| tor signaling | GO:0031929 | 21 | 0.047 | |
| negative regulation of protein serine threonine kinase activity | GO:0071901 | 49 | 0.047 | |
| embryonic epithelial tube formation | GO:0001838 | 130 | 0.047 | |
| generation of precursor metabolites and energy | GO:0006091 | 103 | 0.047 | Yeast |
| positive regulation of gtpase activity | GO:0043547 | 85 | 0.046 | |
| mitochondrion transport along microtubule | GO:0047497 | 3 | 0.046 | |
| regulation of stem cell proliferation | GO:0072091 | 78 | 0.046 | |
| positive regulation of jnk cascade | GO:0046330 | 46 | 0.046 | |
| asymmetric stem cell division | GO:0098722 | 3 | 0.046 | |
| nucleus localization | GO:0051647 | 20 | 0.045 | Worm |
| nucleoside monophosphate metabolic process | GO:0009123 | 85 | 0.045 | |
| platelet activation | GO:0030168 | 40 | 0.045 | |
| cellular response to starvation | GO:0009267 | 57 | 0.044 | |
| multicellular organismal signaling | GO:0035637 | 91 | 0.044 | |
| protein depolymerization | GO:0051261 | 34 | 0.044 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 48 | 0.044 | Yeast |