| response to nutrient levels | GO:0031667 | 370 | 0.556 | Yeast Mouse |
| response to extracellular stimulus | GO:0009991 | 380 | 0.360 | Yeast Mouse |
| response to cytokine | GO:0034097 | 215 | 0.307 | |
| response to nutrient | GO:0007584 | 248 | 0.302 | |
| organic acid biosynthetic process | GO:0016053 | 83 | 0.242 | |
| cellular response to external stimulus | GO:0071496 | 118 | 0.237 | Yeast Mouse |
| response to corticosteroid | GO:0031960 | 235 | 0.194 | |
| single organism catabolic process | GO:0044712 | 283 | 0.168 | Yeast Mouse |
| regulation of apoptotic process | GO:0042981 | 335 | 0.167 | |
| response to peptide hormone | GO:0043434 | 278 | 0.154 | |
| cell projection organization | GO:0030030 | 302 | 0.143 | |
| response to monosaccharide | GO:0034284 | 159 | 0.142 | |
| response to carbohydrate | GO:0009743 | 183 | 0.135 | |
| response to hypoxia | GO:0001666 | 231 | 0.131 | |
| response to inorganic substance | GO:0010035 | 377 | 0.128 | |
| response to oxygen levels | GO:0070482 | 265 | 0.127 | |
| cellular response to stress | GO:0033554 | 269 | 0.117 | Yeast Mouse |
| response to reactive oxygen species | GO:0000302 | 120 | 0.114 | |
| oxoacid metabolic process | GO:0043436 | 290 | 0.112 | |
| response to glucocorticoid | GO:0051384 | 223 | 0.108 | |
| monocarboxylic acid metabolic process | GO:0032787 | 152 | 0.104 | |
| response to external biotic stimulus | GO:0043207 | 221 | 0.095 | Zebrafish Rat Fly |
| lipid metabolic process | GO:0006629 | 283 | 0.091 | |
| cellular response to mechanical stimulus | GO:0071260 | 48 | 0.089 | |
| response to decreased oxygen levels | GO:0036293 | 237 | 0.088 | |
| response to growth factor | GO:0070848 | 189 | 0.088 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 85 | 0.087 | |
| regeneration | GO:0031099 | 163 | 0.087 | |
| regulation of cell proliferation | GO:0042127 | 359 | 0.086 | |
| cellular response to endogenous stimulus | GO:0071495 | 377 | 0.084 | |
| neuron development | GO:0048666 | 286 | 0.080 | |
| cellular response to reactive oxygen species | GO:0034614 | 55 | 0.080 | |
| cellular response to oxygen containing compound | GO:1901701 | 386 | 0.077 | |
| small molecule biosynthetic process | GO:0044283 | 124 | 0.076 | |
| central nervous system development | GO:0007417 | 311 | 0.076 | |
| negative regulation of cell death | GO:0060548 | 229 | 0.070 | |
| cell cell signaling | GO:0007267 | 335 | 0.069 | |
| stress activated protein kinase signaling cascade | GO:0031098 | 37 | 0.067 | |
| regulation of nervous system development | GO:0051960 | 264 | 0.067 | |
| apoptotic process | GO:0006915 | 381 | 0.065 | Fly |
| response to hexose | GO:0009746 | 144 | 0.065 | |
| carboxylic acid biosynthetic process | GO:0046394 | 83 | 0.060 | |
| response to vitamin | GO:0033273 | 131 | 0.059 | |
| response to mechanical stimulus | GO:0009612 | 134 | 0.058 | |
| positive regulation of transport | GO:0051050 | 245 | 0.056 | |
| catabolic process | GO:0009056 | 351 | 0.055 | |
| protein phosphorylation | GO:0006468 | 345 | 0.055 | |
| cellular response to hormone stimulus | GO:0032870 | 247 | 0.055 | |
| developmental process involved in reproduction | GO:0003006 | 159 | 0.055 | Fly |
| response to oxidative stress | GO:0006979 | 186 | 0.054 | |
| response to glucose | GO:0009749 | 136 | 0.053 | |
| carboxylic acid metabolic process | GO:0019752 | 289 | 0.053 | |
| regulation of programmed cell death | GO:0043067 | 341 | 0.052 | |
| programmed cell death | GO:0012501 | 392 | 0.051 | Fly |
| glial cell differentiation | GO:0010001 | 65 | 0.051 | |
| cellular response to nitrogen compound | GO:1901699 | 210 | 0.051 | |
| autophagy | GO:0006914 | 19 | 0.050 | |
| cellular catabolic process | GO:0044248 | 295 | 0.050 | |
| organic acid metabolic process | GO:0006082 | 292 | 0.049 | |
| cellular lipid metabolic process | GO:0044255 | 208 | 0.049 | |
| negative regulation of response to stimulus | GO:0048585 | 155 | 0.049 | |
| reproduction | GO:0000003 | 245 | 0.048 | Fly |
| gliogenesis | GO:0042063 | 93 | 0.043 | |
| homeostatic process | GO:0042592 | 331 | 0.043 | |
| response to vitamin a | GO:0033189 | 36 | 0.042 | |
| gland development | GO:0048732 | 155 | 0.042 | Fly |
| regulation of cell differentiation | GO:0045595 | 320 | 0.041 | |
| response to peptide | GO:1901652 | 292 | 0.040 | |
| negative regulation of cell development | GO:0010721 | 82 | 0.040 | |
| metal ion transport | GO:0030001 | 289 | 0.038 | |
| positive regulation of cell projection organization | GO:0031346 | 111 | 0.036 | |
| circadian rhythm | GO:0007623 | 88 | 0.036 | |
| multicellular organism reproduction | GO:0032504 | 233 | 0.036 | Fly |
| neuron differentiation | GO:0030182 | 368 | 0.036 | |
| signal release | GO:0023061 | 145 | 0.036 | |
| hepaticobiliary system development | GO:0061008 | 90 | 0.036 | |
| translation | GO:0006412 | 35 | 0.035 | |
| positive regulation of cellular component organization | GO:0051130 | 200 | 0.035 | |
| synaptic transmission | GO:0007268 | 235 | 0.035 | |
| neuron projection development | GO:0031175 | 273 | 0.035 | |
| single organism reproductive process | GO:0044702 | 297 | 0.035 | Fly |
| positive regulation of cell death | GO:0010942 | 184 | 0.034 | |
| response to metal ion | GO:0010038 | 253 | 0.034 | |
| regulation of neuron differentiation | GO:0045664 | 208 | 0.034 | |
| positive regulation of multicellular organismal process | GO:0051240 | 387 | 0.034 | |
| response to interleukin 1 | GO:0070555 | 55 | 0.034 | |
| response to insulin | GO:0032868 | 133 | 0.034 | |
| positive regulation of developmental process | GO:0051094 | 283 | 0.033 | |
| negative regulation of natural killer cell mediated immunity | GO:0002716 | 4 | 0.033 | |
| response to organophosphorus | GO:0046683 | 102 | 0.033 | Rat |
| regulation of phosphorylation | GO:0042325 | 248 | 0.033 | |
| cellular chemical homeostasis | GO:0055082 | 247 | 0.033 | |
| negative regulation of neurogenesis | GO:0050768 | 78 | 0.032 | |
| reactive oxygen species biosynthetic process | GO:1903409 | 8 | 0.031 | |
| regulation of cellular component organization | GO:0051128 | 368 | 0.031 | |
| reproductive system development | GO:0061458 | 128 | 0.031 | |
| cellular component biogenesis | GO:0044085 | 368 | 0.031 | Mouse |
| head development | GO:0060322 | 247 | 0.031 | |
| cation transport | GO:0006812 | 382 | 0.031 | |
| regulation of peptide hormone secretion | GO:0090276 | 80 | 0.031 | |
| positive regulation of apoptotic process | GO:0043065 | 154 | 0.031 | |
| response to lipopolysaccharide | GO:0032496 | 191 | 0.031 | Rat |
| regulation of cell projection organization | GO:0031344 | 175 | 0.030 | |
| tissue regeneration | GO:0042246 | 36 | 0.029 | |
| cellular response to nutrient levels | GO:0031669 | 60 | 0.029 | Yeast Mouse |
| ribose phosphate metabolic process | GO:0019693 | 235 | 0.028 | |
| cellular response to abiotic stimulus | GO:0071214 | 85 | 0.028 | |
| positive regulation of peptide hormone secretion | GO:0090277 | 50 | 0.028 | |
| reproductive structure development | GO:0048608 | 128 | 0.028 | |
| cellular response to growth factor stimulus | GO:0071363 | 162 | 0.028 | |
| regulation of cellular amine metabolic process | GO:0033238 | 8 | 0.027 | |
| cellular response to nitric oxide | GO:0071732 | 5 | 0.027 | |
| chemical homeostasis | GO:0048878 | 292 | 0.027 | |
| positive regulation of programmed cell death | GO:0043068 | 157 | 0.027 | |
| protein processing | GO:0016485 | 68 | 0.026 | Rat |
| multi organism reproductive process | GO:0044703 | 262 | 0.026 | Fly |
| cellular response to lipid | GO:0071396 | 201 | 0.025 | |
| aging | GO:0007568 | 241 | 0.025 | |
| chemotaxis | GO:0006935 | 66 | 0.025 | |
| secretion | GO:0046903 | 307 | 0.025 | |
| decidualization | GO:0046697 | 14 | 0.024 | |
| regulation of phosphorus metabolic process | GO:0051174 | 349 | 0.024 | |
| negative regulation of neuron differentiation | GO:0045665 | 62 | 0.023 | |
| positive regulation of nervous system development | GO:0051962 | 178 | 0.023 | |
| membrane fusion | GO:0061025 | 26 | 0.023 | |
| positive regulation of biosynthetic process | GO:0009891 | 319 | 0.023 | |
| multi multicellular organism process | GO:0044706 | 138 | 0.023 | |
| positive regulation of cell development | GO:0010720 | 176 | 0.023 | |
| cellular amino acid metabolic process | GO:0006520 | 107 | 0.023 | |
| multicellular organismal signaling | GO:0035637 | 44 | 0.023 | |
| muscle tissue development | GO:0060537 | 58 | 0.023 | |
| chromatin organization | GO:0006325 | 34 | 0.023 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 295 | 0.022 | |
| response to transition metal nanoparticle | GO:1990267 | 122 | 0.022 | |
| vesicle mediated transport | GO:0016192 | 181 | 0.022 | |
| hormone transport | GO:0009914 | 121 | 0.022 | |
| male mating behavior | GO:0060179 | 3 | 0.022 | |
| regulation of molecular function | GO:0065009 | 398 | 0.022 | |
| organic substance catabolic process | GO:1901575 | 316 | 0.022 | Yeast |
| amide transport | GO:0042886 | 105 | 0.022 | |
| reproductive process | GO:0022414 | 372 | 0.022 | Fly |
| nucleotide metabolic process | GO:0009117 | 279 | 0.022 | |
| growth | GO:0040007 | 165 | 0.022 | |
| negative regulation of cellular component organization | GO:0051129 | 83 | 0.021 | |
| steroid metabolic process | GO:0008202 | 73 | 0.021 | |
| developmental growth | GO:0048589 | 100 | 0.021 | |
| wound healing | GO:0042060 | 122 | 0.021 | |
| cellular component assembly | GO:0022607 | 360 | 0.021 | Mouse |
| actin filament branching | GO:0090135 | 1 | 0.020 | |
| regulation of protein metabolic process | GO:0051246 | 289 | 0.020 | Rat |
| response to increased oxygen levels | GO:0036296 | 45 | 0.020 | |
| nitrogen compound transport | GO:0071705 | 229 | 0.020 | |
| negative regulation of cell proliferation | GO:0008285 | 119 | 0.020 | |
| regulation of secretion by cell | GO:1903530 | 208 | 0.020 | |
| reactive nitrogen species metabolic process | GO:2001057 | 1 | 0.020 | |
| endocytosis | GO:0006897 | 84 | 0.019 | |
| cholesterol homeostasis | GO:0042632 | 3 | 0.019 | |
| brain development | GO:0007420 | 247 | 0.019 | |
| insulin secretion | GO:0030073 | 69 | 0.019 | |
| ion homeostasis | GO:0050801 | 212 | 0.019 | |
| positive regulation of transcription from rna polymerase ii promoter | GO:0045944 | 148 | 0.019 | |
| single organism biosynthetic process | GO:0044711 | 342 | 0.019 | |
| placenta development | GO:0001890 | 22 | 0.019 | |
| carbohydrate catabolic process | GO:0016052 | 40 | 0.019 | |
| carbohydrate derivative catabolic process | GO:1901136 | 147 | 0.019 | |
| cell part morphogenesis | GO:0032990 | 123 | 0.018 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 116 | 0.018 | |
| regulation of anatomical structure size | GO:0090066 | 135 | 0.018 | |
| regulation of multicellular organismal development | GO:2000026 | 376 | 0.018 | |
| regulation of cell size | GO:0008361 | 37 | 0.018 | |
| regulation of neurogenesis | GO:0050767 | 247 | 0.018 | |
| response to acid chemical | GO:0001101 | 222 | 0.018 | |
| negative regulation of extrinsic apoptotic signaling pathway | GO:2001237 | 4 | 0.018 | |
| anatomical structure morphogenesis | GO:0009653 | 298 | 0.018 | Fly |
| organ regeneration | GO:0031100 | 101 | 0.018 | |
| regulation of ion transport | GO:0043269 | 245 | 0.018 | |
| regulation of reactive oxygen species metabolic process | GO:2000377 | 26 | 0.017 | |
| positive regulation of cell communication | GO:0010647 | 271 | 0.017 | |
| regulation of extent of cell growth | GO:0061387 | 25 | 0.017 | |
| regulation of growth | GO:0040008 | 105 | 0.017 | |
| macroautophagy | GO:0016236 | 4 | 0.017 | Mouse |
| regulation of hormone secretion | GO:0046883 | 106 | 0.017 | |
| action potential | GO:0001508 | 54 | 0.017 | |
| female pregnancy | GO:0007565 | 122 | 0.017 | |
| cellular ketone metabolic process | GO:0042180 | 51 | 0.017 | |
| cellular homeostasis | GO:0019725 | 252 | 0.017 | |
| protein homooligomerization | GO:0051260 | 91 | 0.016 | |
| hexose metabolic process | GO:0019318 | 58 | 0.016 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 167 | 0.016 | |
| carbohydrate derivative metabolic process | GO:1901135 | 346 | 0.016 | |
| cell morphogenesis | GO:0000902 | 142 | 0.016 | |
| oligodendrocyte differentiation | GO:0048709 | 32 | 0.016 | |
| negative regulation of neuron projection development | GO:0010977 | 46 | 0.016 | |
| biological adhesion | GO:0022610 | 110 | 0.015 | |
| body fluid secretion | GO:0007589 | 41 | 0.015 | |
| cellular response to hypoxia | GO:0071456 | 51 | 0.015 | |
| endocrine system development | GO:0035270 | 30 | 0.015 | |
| regulation of rna metabolic process | GO:0051252 | 391 | 0.015 | |
| neuronal action potential | GO:0019228 | 35 | 0.015 | |
| cell projection morphogenesis | GO:0048858 | 123 | 0.015 | |
| multicellular organism growth | GO:0035264 | 1 | 0.015 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 197 | 0.015 | |
| regulation of hormone levels | GO:0010817 | 187 | 0.015 | Rat |
| response to ethanol | GO:0045471 | 162 | 0.015 | |
| regulation of axonogenesis | GO:0050770 | 37 | 0.015 | |
| amine metabolic process | GO:0009308 | 38 | 0.015 | |
| regulation of protein modification process | GO:0031399 | 194 | 0.015 | |
| regulation of response to external stimulus | GO:0032101 | 106 | 0.015 | |
| cellular component morphogenesis | GO:0032989 | 155 | 0.015 | |
| response to wounding | GO:0009611 | 254 | 0.015 | |
| transmission of nerve impulse | GO:0019226 | 42 | 0.014 | |
| cellular response to inorganic substance | GO:0071241 | 65 | 0.014 | |
| regulation of neuron projection development | GO:0010975 | 161 | 0.014 | |
| axonogenesis | GO:0007409 | 71 | 0.014 | |
| positive regulation of hormone secretion | GO:0046887 | 65 | 0.014 | |
| regulation of cell growth | GO:0001558 | 85 | 0.014 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 3 | 0.014 | |
| cellular amine metabolic process | GO:0044106 | 38 | 0.014 | |
| locomotion | GO:0040011 | 237 | 0.014 | |
| response to other organism | GO:0051707 | 220 | 0.014 | Zebrafish Rat Fly |
| negative regulation of cellular protein metabolic process | GO:0032269 | 106 | 0.014 | |
| collagen catabolic process | GO:0030574 | 2 | 0.014 | |
| transcription from rna polymerase ii promoter | GO:0006366 | 252 | 0.014 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 234 | 0.014 | |
| positive regulation of gene expression | GO:0010628 | 244 | 0.014 | |
| peptide secretion | GO:0002790 | 86 | 0.014 | |
| macromolecular complex subunit organization | GO:0043933 | 339 | 0.014 | |
| purine containing compound metabolic process | GO:0072521 | 253 | 0.014 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 197 | 0.013 | |
| multicellular organismal catabolic process | GO:0044243 | 2 | 0.013 | |
| carbohydrate metabolic process | GO:0005975 | 130 | 0.013 | |
| carboxylic acid transport | GO:0046942 | 115 | 0.013 | |
| neuron projection regeneration | GO:0031102 | 35 | 0.013 | |
| regulation of vesicle mediated transport | GO:0060627 | 81 | 0.013 | |
| cellular response to extracellular stimulus | GO:0031668 | 73 | 0.013 | Yeast Mouse |
| positive regulation of neurogenesis | GO:0050769 | 165 | 0.013 | |
| negative regulation of cell communication | GO:0010648 | 158 | 0.013 | |
| cell growth | GO:0016049 | 104 | 0.013 | |
| axon ensheathment | GO:0008366 | 40 | 0.013 | |
| proteolysis | GO:0006508 | 175 | 0.013 | |
| anion transport | GO:0006820 | 178 | 0.013 | |
| response to light stimulus | GO:0009416 | 52 | 0.013 | |
| hormone secretion | GO:0046879 | 115 | 0.013 | |
| positive regulation of insulin secretion | GO:0032024 | 36 | 0.013 | |
| regulation of cell development | GO:0060284 | 263 | 0.013 | |
| salivary gland development | GO:0007431 | 3 | 0.013 | Fly |
| cell cell signaling involved in cell fate commitment | GO:0045168 | 2 | 0.012 | |
| cellular response to insulin stimulus | GO:0032869 | 81 | 0.012 | |
| cellular amino acid biosynthetic process | GO:0008652 | 32 | 0.012 | |
| negative regulation of nervous system development | GO:0051961 | 79 | 0.012 | |
| nucleoside phosphate metabolic process | GO:0006753 | 283 | 0.012 | |
| positive regulation of neuron differentiation | GO:0045666 | 126 | 0.012 | |
| fatty acid metabolic process | GO:0006631 | 99 | 0.012 | |
| multicellular organismal macromolecule metabolic process | GO:0044259 | 21 | 0.012 | |
| negative regulation of apoptotic process | GO:0043066 | 181 | 0.012 | |
| regulation of lipid metabolic process | GO:0019216 | 68 | 0.012 | |
| positive regulation of dna metabolic process | GO:0051054 | 39 | 0.012 | |
| cellular metal ion homeostasis | GO:0006875 | 172 | 0.012 | |
| pattern recognition receptor signaling pathway | GO:0002221 | 9 | 0.012 | |
| response to hyperoxia | GO:0055093 | 45 | 0.012 | |
| generation of precursor metabolites and energy | GO:0006091 | 62 | 0.012 | |
| regulation of peptide secretion | GO:0002791 | 82 | 0.012 | |
| positive regulation of necrotic cell death | GO:0010940 | 4 | 0.011 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 84 | 0.011 | |
| positive regulation of peptide secretion | GO:0002793 | 52 | 0.011 | |
| secretion by cell | GO:0032940 | 248 | 0.011 | |
| positive regulation of ion transport | GO:0043270 | 94 | 0.011 | |
| neuron projection morphogenesis | GO:0048812 | 122 | 0.011 | |
| response to estrogen | GO:0043627 | 232 | 0.011 | |
| regulation of dna metabolic process | GO:0051052 | 60 | 0.011 | |
| protein localization | GO:0008104 | 191 | 0.011 | |
| dendrite development | GO:0016358 | 72 | 0.011 | |
| steroid biosynthetic process | GO:0006694 | 48 | 0.010 | |
| single organism intracellular transport | GO:1902582 | 166 | 0.010 | |
| glycogen metabolic process | GO:0005977 | 23 | 0.010 | |
| negative regulation of cell growth | GO:0030308 | 33 | 0.010 | |
| striated muscle tissue development | GO:0014706 | 58 | 0.010 | |
| negative regulation of multicellular organismal process | GO:0051241 | 203 | 0.010 | |
| axon extension | GO:0048675 | 26 | 0.010 | |
| regulation of rna biosynthetic process | GO:2001141 | 381 | 0.010 | |
| peptide hormone secretion | GO:0030072 | 84 | 0.010 | |
| negative regulation of signaling | GO:0023057 | 157 | 0.010 | |
| negative regulation of axon guidance | GO:1902668 | 3 | 0.010 | |
| positive regulation of molecular function | GO:0044093 | 230 | 0.010 | |
| response to camp | GO:0051591 | 91 | 0.010 | Rat |
| maternal process involved in female pregnancy | GO:0060135 | 38 | 0.010 | |
| response to estradiol | GO:0032355 | 164 | 0.010 | |
| response to fibroblast growth factor | GO:0071774 | 29 | 0.010 | |
| reactive oxygen species metabolic process | GO:0072593 | 37 | 0.010 | |