Rattus norvegicus

12 known processes

Ctsd

cathepsin D

Ctsd biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to nutrient levelsGO:00316673700.556
Yeast Mouse
response to extracellular stimulusGO:00099913800.360
Yeast Mouse
response to cytokineGO:00340972150.307
response to nutrientGO:00075842480.302
organic acid biosynthetic processGO:0016053830.242
cellular response to external stimulusGO:00714961180.237
Yeast Mouse
response to corticosteroidGO:00319602350.194
single organism catabolic processGO:00447122830.168
Yeast Mouse
regulation of apoptotic processGO:00429813350.167
response to peptide hormoneGO:00434342780.154
cell projection organizationGO:00300303020.143
response to monosaccharideGO:00342841590.142
response to carbohydrateGO:00097431830.135
response to hypoxiaGO:00016662310.131
response to inorganic substanceGO:00100353770.128
response to oxygen levelsGO:00704822650.127
cellular response to stressGO:00335542690.117
Yeast Mouse
response to reactive oxygen speciesGO:00003021200.114
oxoacid metabolic processGO:00434362900.112
response to glucocorticoidGO:00513842230.108
monocarboxylic acid metabolic processGO:00327871520.104
response to external biotic stimulusGO:00432072210.095
Zebrafish Rat Fly
lipid metabolic processGO:00066292830.091
cellular response to mechanical stimulusGO:0071260480.089
response to decreased oxygen levelsGO:00362932370.088
response to growth factorGO:00708481890.088
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.087
regenerationGO:00310991630.087
regulation of cell proliferationGO:00421273590.086
cellular response to endogenous stimulusGO:00714953770.084
neuron developmentGO:00486662860.080
cellular response to reactive oxygen speciesGO:0034614550.080
cellular response to oxygen containing compoundGO:19017013860.077
small molecule biosynthetic processGO:00442831240.076
central nervous system developmentGO:00074173110.076
negative regulation of cell deathGO:00605482290.070
cell cell signalingGO:00072673350.069
stress activated protein kinase signaling cascadeGO:0031098370.067
regulation of nervous system developmentGO:00519602640.067
apoptotic processGO:00069153810.065
Fly
response to hexoseGO:00097461440.065
carboxylic acid biosynthetic processGO:0046394830.060
response to vitaminGO:00332731310.059
response to mechanical stimulusGO:00096121340.058
positive regulation of transportGO:00510502450.056
catabolic processGO:00090563510.055
protein phosphorylationGO:00064683450.055
cellular response to hormone stimulusGO:00328702470.055
developmental process involved in reproductionGO:00030061590.055
Fly
response to oxidative stressGO:00069791860.054
response to glucoseGO:00097491360.053
carboxylic acid metabolic processGO:00197522890.053
regulation of programmed cell deathGO:00430673410.052
programmed cell deathGO:00125013920.051
Fly
glial cell differentiationGO:0010001650.051
cellular response to nitrogen compoundGO:19016992100.051
autophagyGO:0006914190.050
cellular catabolic processGO:00442482950.050
organic acid metabolic processGO:00060822920.049
cellular lipid metabolic processGO:00442552080.049
negative regulation of response to stimulusGO:00485851550.049
reproductionGO:00000032450.048
Fly
gliogenesisGO:0042063930.043
homeostatic processGO:00425923310.043
response to vitamin aGO:0033189360.042
gland developmentGO:00487321550.042
Fly
regulation of cell differentiationGO:00455953200.041
response to peptideGO:19016522920.040
negative regulation of cell developmentGO:0010721820.040
metal ion transportGO:00300012890.038
positive regulation of cell projection organizationGO:00313461110.036
circadian rhythmGO:0007623880.036
multicellular organism reproductionGO:00325042330.036
Fly
neuron differentiationGO:00301823680.036
signal releaseGO:00230611450.036
hepaticobiliary system developmentGO:0061008900.036
translationGO:0006412350.035
positive regulation of cellular component organizationGO:00511302000.035
synaptic transmissionGO:00072682350.035
neuron projection developmentGO:00311752730.035
single organism reproductive processGO:00447022970.035
Fly
positive regulation of cell deathGO:00109421840.034
response to metal ionGO:00100382530.034
regulation of neuron differentiationGO:00456642080.034
positive regulation of multicellular organismal processGO:00512403870.034
response to interleukin 1GO:0070555550.034
response to insulinGO:00328681330.034
positive regulation of developmental processGO:00510942830.033
negative regulation of natural killer cell mediated immunityGO:000271640.033
response to organophosphorusGO:00466831020.033
Rat
regulation of phosphorylationGO:00423252480.033
cellular chemical homeostasisGO:00550822470.033
negative regulation of neurogenesisGO:0050768780.032
reactive oxygen species biosynthetic processGO:190340980.031
regulation of cellular component organizationGO:00511283680.031
reproductive system developmentGO:00614581280.031
cellular component biogenesisGO:00440853680.031
Mouse
head developmentGO:00603222470.031
cation transportGO:00068123820.031
regulation of peptide hormone secretionGO:0090276800.031
positive regulation of apoptotic processGO:00430651540.031
response to lipopolysaccharideGO:00324961910.031
Rat
regulation of cell projection organizationGO:00313441750.030
tissue regenerationGO:0042246360.029
cellular response to nutrient levelsGO:0031669600.029
Yeast Mouse
ribose phosphate metabolic processGO:00196932350.028
cellular response to abiotic stimulusGO:0071214850.028
positive regulation of peptide hormone secretionGO:0090277500.028
reproductive structure developmentGO:00486081280.028
cellular response to growth factor stimulusGO:00713631620.028
regulation of cellular amine metabolic processGO:003323880.027
cellular response to nitric oxideGO:007173250.027
chemical homeostasisGO:00488782920.027
positive regulation of programmed cell deathGO:00430681570.027
protein processingGO:0016485680.026
Rat
multi organism reproductive processGO:00447032620.026
Fly
cellular response to lipidGO:00713962010.025
agingGO:00075682410.025
chemotaxisGO:0006935660.025
secretionGO:00469033070.025
decidualizationGO:0046697140.024
regulation of phosphorus metabolic processGO:00511743490.024
negative regulation of neuron differentiationGO:0045665620.023
positive regulation of nervous system developmentGO:00519621780.023
membrane fusionGO:0061025260.023
positive regulation of biosynthetic processGO:00098913190.023
multi multicellular organism processGO:00447061380.023
positive regulation of cell developmentGO:00107201760.023
cellular amino acid metabolic processGO:00065201070.023
multicellular organismal signalingGO:0035637440.023
muscle tissue developmentGO:0060537580.023
chromatin organizationGO:0006325340.023
positive regulation of cellular biosynthetic processGO:00313282950.022
response to transition metal nanoparticleGO:19902671220.022
vesicle mediated transportGO:00161921810.022
hormone transportGO:00099141210.022
male mating behaviorGO:006017930.022
regulation of molecular functionGO:00650093980.022
organic substance catabolic processGO:19015753160.022
Yeast
amide transportGO:00428861050.022
reproductive processGO:00224143720.022
Fly
nucleotide metabolic processGO:00091172790.022
growthGO:00400071650.022
negative regulation of cellular component organizationGO:0051129830.021
steroid metabolic processGO:0008202730.021
developmental growthGO:00485891000.021
wound healingGO:00420601220.021
cellular component assemblyGO:00226073600.021
Mouse
actin filament branchingGO:009013510.020
regulation of protein metabolic processGO:00512462890.020
Rat
response to increased oxygen levelsGO:0036296450.020
nitrogen compound transportGO:00717052290.020
negative regulation of cell proliferationGO:00082851190.020
regulation of secretion by cellGO:19035302080.020
reactive nitrogen species metabolic processGO:200105710.020
endocytosisGO:0006897840.019
cholesterol homeostasisGO:004263230.019
brain developmentGO:00074202470.019
insulin secretionGO:0030073690.019
ion homeostasisGO:00508012120.019
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.019
single organism biosynthetic processGO:00447113420.019
placenta developmentGO:0001890220.019
carbohydrate catabolic processGO:0016052400.019
carbohydrate derivative catabolic processGO:19011361470.019
cell part morphogenesisGO:00329901230.018
enzyme linked receptor protein signaling pathwayGO:00071671160.018
regulation of anatomical structure sizeGO:00900661350.018
regulation of multicellular organismal developmentGO:20000263760.018
regulation of cell sizeGO:0008361370.018
regulation of neurogenesisGO:00507672470.018
response to acid chemicalGO:00011012220.018
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.018
anatomical structure morphogenesisGO:00096532980.018
Fly
organ regenerationGO:00311001010.018
regulation of ion transportGO:00432692450.018
regulation of reactive oxygen species metabolic processGO:2000377260.017
positive regulation of cell communicationGO:00106472710.017
regulation of extent of cell growthGO:0061387250.017
regulation of growthGO:00400081050.017
macroautophagyGO:001623640.017
Mouse
regulation of hormone secretionGO:00468831060.017
action potentialGO:0001508540.017
female pregnancyGO:00075651220.017
cellular ketone metabolic processGO:0042180510.017
cellular homeostasisGO:00197252520.017
protein homooligomerizationGO:0051260910.016
hexose metabolic processGO:0019318580.016
organonitrogen compound biosynthetic processGO:19015661670.016
carbohydrate derivative metabolic processGO:19011353460.016
cell morphogenesisGO:00009021420.016
oligodendrocyte differentiationGO:0048709320.016
negative regulation of neuron projection developmentGO:0010977460.016
biological adhesionGO:00226101100.015
body fluid secretionGO:0007589410.015
cellular response to hypoxiaGO:0071456510.015
endocrine system developmentGO:0035270300.015
regulation of rna metabolic processGO:00512523910.015
neuronal action potentialGO:0019228350.015
cell projection morphogenesisGO:00488581230.015
multicellular organism growthGO:003526410.015
positive regulation of rna biosynthetic processGO:19026801970.015
regulation of hormone levelsGO:00108171870.015
Rat
response to ethanolGO:00454711620.015
regulation of axonogenesisGO:0050770370.015
amine metabolic processGO:0009308380.015
regulation of protein modification processGO:00313991940.015
regulation of response to external stimulusGO:00321011060.015
cellular component morphogenesisGO:00329891550.015
response to woundingGO:00096112540.015
transmission of nerve impulseGO:0019226420.014
cellular response to inorganic substanceGO:0071241650.014
regulation of neuron projection developmentGO:00109751610.014
axonogenesisGO:0007409710.014
positive regulation of hormone secretionGO:0046887650.014
regulation of cell growthGO:0001558850.014
positive regulation of cellular amine metabolic processGO:003324030.014
cellular amine metabolic processGO:0044106380.014
locomotionGO:00400112370.014
response to other organismGO:00517072200.014
Zebrafish Rat Fly
negative regulation of cellular protein metabolic processGO:00322691060.014
collagen catabolic processGO:003057420.014
transcription from rna polymerase ii promoterGO:00063662520.014
regulation of transcription from rna polymerase ii promoterGO:00063572340.014
positive regulation of gene expressionGO:00106282440.014
peptide secretionGO:0002790860.014
macromolecular complex subunit organizationGO:00439333390.014
purine containing compound metabolic processGO:00725212530.014
positive regulation of nucleic acid templated transcriptionGO:19035081970.013
multicellular organismal catabolic processGO:004424320.013
carbohydrate metabolic processGO:00059751300.013
carboxylic acid transportGO:00469421150.013
neuron projection regenerationGO:0031102350.013
regulation of vesicle mediated transportGO:0060627810.013
cellular response to extracellular stimulusGO:0031668730.013
Yeast Mouse
positive regulation of neurogenesisGO:00507691650.013
negative regulation of cell communicationGO:00106481580.013
cell growthGO:00160491040.013
axon ensheathmentGO:0008366400.013
proteolysisGO:00065081750.013
anion transportGO:00068201780.013
response to light stimulusGO:0009416520.013
hormone secretionGO:00468791150.013
positive regulation of insulin secretionGO:0032024360.013
regulation of cell developmentGO:00602842630.013
salivary gland developmentGO:000743130.013
Fly
cell cell signaling involved in cell fate commitmentGO:004516820.012
cellular response to insulin stimulusGO:0032869810.012
cellular amino acid biosynthetic processGO:0008652320.012
negative regulation of nervous system developmentGO:0051961790.012
nucleoside phosphate metabolic processGO:00067532830.012
positive regulation of neuron differentiationGO:00456661260.012
fatty acid metabolic processGO:0006631990.012
multicellular organismal macromolecule metabolic processGO:0044259210.012
negative regulation of apoptotic processGO:00430661810.012
regulation of lipid metabolic processGO:0019216680.012
positive regulation of dna metabolic processGO:0051054390.012
cellular metal ion homeostasisGO:00068751720.012
pattern recognition receptor signaling pathwayGO:000222190.012
response to hyperoxiaGO:0055093450.012
generation of precursor metabolites and energyGO:0006091620.012
regulation of peptide secretionGO:0002791820.012
positive regulation of necrotic cell deathGO:001094040.011
purine ribonucleoside monophosphate metabolic processGO:0009167840.011
positive regulation of peptide secretionGO:0002793520.011
secretion by cellGO:00329402480.011
positive regulation of ion transportGO:0043270940.011
neuron projection morphogenesisGO:00488121220.011
response to estrogenGO:00436272320.011
regulation of dna metabolic processGO:0051052600.011
protein localizationGO:00081041910.011
dendrite developmentGO:0016358720.011
steroid biosynthetic processGO:0006694480.010
single organism intracellular transportGO:19025821660.010
glycogen metabolic processGO:0005977230.010
negative regulation of cell growthGO:0030308330.010
striated muscle tissue developmentGO:0014706580.010
negative regulation of multicellular organismal processGO:00512412030.010
axon extensionGO:0048675260.010
regulation of rna biosynthetic processGO:20011413810.010
peptide hormone secretionGO:0030072840.010
negative regulation of signalingGO:00230571570.010
negative regulation of axon guidanceGO:190266830.010
positive regulation of molecular functionGO:00440932300.010
response to campGO:0051591910.010
Rat
maternal process involved in female pregnancyGO:0060135380.010
response to estradiolGO:00323551640.010
response to fibroblast growth factorGO:0071774290.010
reactive oxygen species metabolic processGO:0072593370.010

Ctsd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.027
disease of anatomical entityDOID:700.027
nervous system diseaseDOID:86300.024
connective tissue diseaseDOID:6500.013
bone diseaseDOID:008000100.013