Rattus norvegicus

19 known processes

Sp4

Sp4 transcription factor

(Aliases: HF-1b)

Sp4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuron projection developmentGO:00311752730.570
cell projection organizationGO:00300303020.408
tissue developmentGO:00098882520.364
transcription dna templatedGO:00063513770.244
regulation of transcription from rna polymerase ii promoterGO:00063572340.241
cellular component morphogenesisGO:00329891550.239
rna biosynthetic processGO:00327743800.217
regulation of transcription dna templatedGO:00063553740.216
regulation of nucleic acid templated transcriptionGO:19035063800.169
circulatory system developmentGO:00723591340.168
neuron developmentGO:00486662860.164
reproductionGO:00000032450.159
positive regulation of synaptic vesicle exocytosisGO:200030230.156
anatomical structure morphogenesisGO:00096532980.156
positive regulation of transcription dna templatedGO:00458931970.151
regulation of rna metabolic processGO:00512523910.140
axon developmentGO:0061564960.139
transcription from rna polymerase ii promoterGO:00063662520.136
cell part morphogenesisGO:00329901230.128
neuron differentiationGO:00301823680.126
transmembrane transportGO:00550854120.123
single organism reproductive processGO:00447022970.123
multicellular organismal reproductive processGO:00486092330.122
apoptotic processGO:00069153810.121
cardiovascular system developmentGO:00723581340.118
synaptic transmissionGO:00072682350.116
positive regulation of developmental processGO:00510942830.116
cellular component assemblyGO:00226073600.109
rna metabolic processGO:00160704060.106
multi organism reproductive processGO:00447032620.105
cell projection morphogenesisGO:00488581230.103
regulation of cell developmentGO:00602842630.097
protein localizationGO:00081041910.096
regulation of protein metabolic processGO:00512462890.095
multicellular organism reproductionGO:00325042330.094
nucleic acid templated transcriptionGO:00976593790.092
cell morphogenesis involved in neuron differentiationGO:00486671060.088
positive regulation of gene expressionGO:00106282440.084
cell motilityGO:00488702020.084
neuron projection morphogenesisGO:00488121220.081
macromolecular complex subunit organizationGO:00439333390.080
positive regulation of secretionGO:00510471400.073
regulation of rna biosynthetic processGO:20011413810.072
inorganic ion transmembrane transportGO:00986602290.072
regulation of nervous system developmentGO:00519602640.071
regulation of multicellular organismal developmentGO:20000263760.071
positive regulation of multicellular organismal processGO:00512403870.070
behaviorGO:00076102050.070
male mating behaviorGO:006017930.070
locomotionGO:00400112370.069
dendrite morphogenesisGO:0048813430.068
regulation of cell projection organizationGO:00313441750.068
epithelial cell differentiationGO:0030855710.067
cellular component biogenesisGO:00440853680.067
cell morphogenesisGO:00009021420.067
negative regulation of metabolic processGO:00098923310.065
positive regulation of cellular component organizationGO:00511302000.065
negative regulation of gene expressionGO:00106291990.065
regulation of cellular component organizationGO:00511283680.064
positive regulation of macromolecule biosynthetic processGO:00105572470.062
cell adhesionGO:00071551100.062
positive regulation of cell projection organizationGO:00313461110.061
establishment of vesicle localizationGO:0051650310.060
protein complex assemblyGO:00064612630.060
epithelium developmentGO:0060429960.060
positive regulation of nervous system developmentGO:00519621780.059
regulation of cellular localizationGO:00603412630.059
wound healingGO:00420601220.059
regulation of system processGO:00440572080.056
regulation of cellular protein metabolic processGO:00322682670.056
cellular component movementGO:00069282480.056
programmed cell deathGO:00125013920.055
protein complex biogenesisGO:00702712630.055
gamete generationGO:00072761240.055
cell morphogenesis involved in differentiationGO:00009041190.054
reproductive processGO:00224143720.054
organelle localizationGO:0051640550.053
regulation of ion transportGO:00432692450.053
positive regulation of synaptic vesicle transportGO:190280530.052
macromolecular complex assemblyGO:00650032730.052
localization of cellGO:00516742020.051
response to nutrientGO:00075842480.051
establishment of organelle localizationGO:0051656370.051
cellular macromolecule localizationGO:00707271220.050
positive regulation of nucleobase containing compound metabolic processGO:00459353190.050
positive regulation of neuron projection developmentGO:0010976990.049
macromolecule localizationGO:00330362520.049
cation transmembrane transportGO:00986552630.049
positive regulation of cell differentiationGO:00455972170.049
intracellular transportGO:00469071850.049
inorganic cation transmembrane transportGO:00986622020.049
regulation of response to stressGO:00801341260.049
organ morphogenesisGO:0009887750.048
protein complex subunit organizationGO:00718223020.048
cellular response to peptideGO:19016531330.048
central nervous system developmentGO:00074173110.047
negative regulation of macromolecule metabolic processGO:00106052600.046
response to extracellular stimulusGO:00099913800.045
positive regulation of nitrogen compound metabolic processGO:00511733340.045
cell cell signalingGO:00072673350.044
monovalent inorganic cation transportGO:00156721720.044
organelle organizationGO:00069962660.044
positive regulation of neurogenesisGO:00507691650.043
axonogenesisGO:0007409710.043
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.042
positive regulation of rna metabolic processGO:00512542030.041
dendrite developmentGO:0016358720.041
positive regulation of neuron differentiationGO:00456661260.041
actin filament based processGO:0030029860.041
positive regulation of molecular functionGO:00440932300.041
alternative mrna splicing via spliceosomeGO:000038040.041
negative regulation of biosynthetic processGO:00098901680.041
regulation of locomotionGO:00400121480.040
regulation of cell differentiationGO:00455953200.039
cell migrationGO:00164771970.039
regulation of neuron projection developmentGO:00109751610.039
developmental process involved in reproductionGO:00030061590.039
regulation of apoptotic processGO:00429813350.039
taxisGO:0042330670.038
secretion by cellGO:00329402480.038
developmental growthGO:00485891000.037
regulation of neurogenesisGO:00507672470.037
neuromuscular synaptic transmissionGO:000727420.037
heart developmentGO:0007507720.037
cellular response to stressGO:00335542690.037
brain developmentGO:00074202470.036
ion transmembrane transportGO:00342203650.036
positive regulation of transportGO:00510502450.035
receptor localization to synapseGO:009712020.035
biological adhesionGO:00226101100.035
response to growth factorGO:00708481890.035
positive regulation of cell deathGO:00109421840.034
negative regulation of cellular metabolic processGO:00313242810.034
negative regulation of cellular protein metabolic processGO:00322691060.034
response to peptide hormoneGO:00434342780.034
rhythmic processGO:00485111560.033
axis specificationGO:000979840.032
regulation of signal transductionGO:00099663180.032
regulation of programmed cell deathGO:00430673410.032
sexual reproductionGO:00199531480.032
response to ketoneGO:19016541820.032
intracellular signal transductionGO:00355563140.032
muscle system processGO:00030121150.031
ras protein signal transductionGO:0007265290.031
positive regulation of cell developmentGO:00107201760.031
negative regulation of nucleic acid templated transcriptionGO:19035071170.031
head developmentGO:00603222470.031
response to hypoxiaGO:00016662310.031
positive regulation of rna biosynthetic processGO:19026801970.031
response to woundingGO:00096112540.030
neurological system processGO:00508772190.030
embryonic pattern specificationGO:000988010.030
multicellular organism growthGO:003526410.030
circadian rhythmGO:0007623880.030
regulation of cellular component biogenesisGO:0044087860.029
anterior posterior pattern specificationGO:000995210.029
synaptic growth at neuromuscular junctionGO:005112410.028
cation transportGO:00068123820.028
agingGO:00075682410.028
response to metal ionGO:00100382530.028
response to nutrient levelsGO:00316673700.027
positive regulation of cell communicationGO:00106472710.027
negative regulation of cellular biosynthetic processGO:00313271610.027
lipid metabolic processGO:00066292830.026
carboxylic acid metabolic processGO:00197522890.026
ovulation cycleGO:0042698670.026
negative regulation of nitrogen compound metabolic processGO:00511721610.026
positive regulation of biosynthetic processGO:00098913190.026
regulation of synaptic transmissionGO:00508041410.026
single organism organelle organizationGO:19025891800.026
cellular response to nitrogen compoundGO:19016992100.026
cellular response to endogenous stimulusGO:00714953770.025
potassium ion transmembrane transportGO:0071805710.025
negative regulation of nucleobase containing compound metabolic processGO:00459341530.024
cellular amino acid metabolic processGO:00065201070.024
deoxyribonucleoside monophosphate metabolic processGO:000916260.024
melanocyte differentiationGO:003031820.023
response to estrogenGO:00436272320.023
cellular protein localizationGO:00346131220.023
cellular response to hormone stimulusGO:00328702470.023
response to ethanolGO:00454711620.022
cellular catabolic processGO:00442482950.022
positive regulation of nucleic acid templated transcriptionGO:19035081970.022
negative regulation of macromolecule biosynthetic processGO:00105581480.022
regulation of mrna splicing via spliceosomeGO:004802430.022
small gtpase mediated signal transductionGO:0007264360.022
dna metabolic processGO:0006259960.022
positive regulation of ion transportGO:0043270940.022
deoxyribonucleoside monophosphate biosynthetic processGO:000915740.022
negative regulation of programmed cell deathGO:00430691830.022
negative regulation of transcription dna templatedGO:00458921160.022
defecationGO:003042110.021
response to peptideGO:19016522920.021
regulation of cell proliferationGO:00421273590.021
regulation of molecular functionGO:00650093980.021
positive regulation of secretion by cellGO:19035321280.021
membrane organizationGO:0061024940.021
organic substance catabolic processGO:19015753160.021
regulation of cellular ketone metabolic processGO:0010565270.021
regulation of body fluid levelsGO:0050878900.021
secretionGO:00469033070.021
metal ion transportGO:00300012890.020
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001088040.020
response to decreased oxygen levelsGO:00362932370.020
cytoskeleton organizationGO:00070101110.020
vesicle mediated transportGO:00161921810.020
negative regulation of protein metabolic processGO:00512481140.020
ovulation cycle processGO:0022602500.020
single organism catabolic processGO:00447122830.020
cellular response to insulin stimulusGO:0032869810.019
cation homeostasisGO:00550801950.019
cellular amine metabolic processGO:0044106380.019
synaptic vesicle primingGO:001608240.019
regulation of dendrite developmentGO:0050773590.019
protein transportGO:00150311320.019
cellular response to organonitrogen compoundGO:00714171970.019
establishment of synaptic vesicle localizationGO:0097480230.019
vasculature developmentGO:0001944700.019
response to insulinGO:00328681330.019
organophosphate metabolic processGO:00196373700.019
spermatogenesisGO:0007283990.019
catabolic processGO:00090563510.019
regulation of cellular amine metabolic processGO:003323880.019
regulation of hormone levelsGO:00108171870.018
signal releaseGO:00230611450.018
male gamete generationGO:0048232990.018
regulation of cell migrationGO:00303341280.018
organonitrogen compound catabolic processGO:19015651790.018
regulation of axonogenesisGO:0050770370.018
muscle structure developmentGO:0061061870.018
positive regulation of synaptic vesicle recyclingGO:190342310.018
cell type specific apoptotic processGO:00972851340.018
homeostatic processGO:00425923310.018
tube developmentGO:0035295890.018
g protein coupled receptor signaling pathwayGO:00071862420.018
negative regulation of rna biosynthetic processGO:19026791180.018
regulation of membrane potentialGO:00423911100.018
transmission of nerve impulseGO:0019226420.018
positive regulation of cellular biosynthetic processGO:00313282950.018
proteolysisGO:00065081750.018
regulation of cell morphogenesis involved in differentiationGO:0010769720.018
protein heterooligomerizationGO:0051291890.017
cellular response to peptide hormone stimulusGO:00713751200.017
cellular ketone metabolic processGO:0042180510.017
salivary gland developmentGO:000743130.017
ensheathment of neuronsGO:0007272400.017
regulation of cellular amino acid metabolic processGO:000652120.017
pteridine containing compound metabolic processGO:0042558140.017
carbohydrate derivative metabolic processGO:19011353460.017
negative regulation of cell communicationGO:00106481580.017
chemical homeostasisGO:00488782920.017
response to vitaminGO:00332731310.017
regulation of secretion by cellGO:19035302080.017
locomotor rhythmGO:004547510.017
organ regenerationGO:00311001010.016
regulation of canonical wnt signaling pathwayGO:006082840.016
neuron apoptotic processGO:0051402880.016
negative regulation of transportGO:00510511360.016
embryonic axis specificationGO:000057810.016
regulation of phosphorylationGO:00423252480.016
positive regulation of phosphate metabolic processGO:00459372620.016
anion transportGO:00068201780.016
embryo developmentGO:0009790490.016
chromosome segregationGO:000705920.016
forebrain developmentGO:0030900980.016
neuronal action potentialGO:0019228350.016
protein phosphorylationGO:00064683450.016
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.016
sensory perceptionGO:00076001010.016
regulation of phosphorus metabolic processGO:00511743490.016
regulation of protein phosphorylationGO:00019321830.016
single organism biosynthetic processGO:00447113420.016
response to inorganic substanceGO:00100353770.016
positive regulation of cell migrationGO:0030335960.015
regulation of transferase activityGO:00513381230.015
regulation of catalytic activityGO:00507903040.015
regulation of cellular component movementGO:00512701500.015
positive regulation of phosphorus metabolic processGO:00105622620.015
muscle cell proliferationGO:0033002840.015
response to glucoseGO:00097491360.015
regulation of developmental growthGO:0048638450.015
cellular lipid metabolic processGO:00442552080.015
morphogenesis of an epitheliumGO:0002009200.015
regulation of anatomical structure morphogenesisGO:00226031410.015
organic acid metabolic processGO:00060822920.014
cellular response to oxygen containing compoundGO:19017013860.014
regulation of catabolic processGO:00098941130.014
negative regulation of cell proliferationGO:00082851190.014
negative regulation of response to stimulusGO:00485851550.014
regulation of hormone secretionGO:00468831060.014
regulation of cell motilityGO:20001451310.014
reproductive structure developmentGO:00486081280.014
oxoacid metabolic processGO:00434362900.014
negative regulation of molecular functionGO:00440921330.014
nucleobase containing small molecule metabolic processGO:00550863160.014
cytosolic calcium ion homeostasisGO:00514801400.014
cognitionGO:0050890920.014
regulation of neuron differentiationGO:00456642080.014
organic hydroxy compound transportGO:0015850770.014
nucleoside phosphate metabolic processGO:00067532830.014
regulation of metal ion transportGO:00109591180.014
neuronal ion channel clusteringGO:004516130.014
negative regulation of multicellular organismal processGO:00512412030.014
regulation of cell morphogenesisGO:0022604770.014
purine containing compound catabolic processGO:00725231380.014
positive regulation of apoptotic processGO:00430651540.013
single organism cellular localizationGO:19025801020.013
regulation of blood circulationGO:19035221100.013
positive regulation of hormone secretionGO:0046887650.013
actin cytoskeleton organizationGO:0030036730.013
behavioral response to ethanolGO:004814910.013
amide biosynthetic processGO:0043604100.013
hormone secretionGO:00468791150.013
vesicle localizationGO:0051648330.013
release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001480840.013
amine metabolic processGO:0009308380.013
regulation of homeostatic processGO:00328441010.013
positive regulation of catalytic activityGO:00430851840.013
organophosphate biosynthetic processGO:00904071430.013
muscle organ developmentGO:0007517500.013
positive regulation of cell proliferationGO:00082842490.013
protein oligomerizationGO:00512591910.013
cellular divalent inorganic cation homeostasisGO:00725031620.013
hair cell differentiationGO:003531520.013
dna replicationGO:0006260370.013
cellular response to transforming growth factor beta stimulusGO:0071560410.013
developmental maturationGO:0021700250.013
columnar cuboidal epithelial cell differentiationGO:000206580.013
ribonucleotide metabolic processGO:00092592310.013
heart morphogenesisGO:000300730.013
maintenance of locationGO:0051235170.013
cell cycle checkpointGO:000007520.013
cytoplasmic transportGO:00164821150.013
lipid modificationGO:0030258520.012
cellular response to oxidative stressGO:0034599760.012
regulation of sodium ion transmembrane transporter activityGO:200064940.012
cellular macromolecular complex assemblyGO:0034622580.012
positive regulation of protein modification processGO:00314011420.012
positive regulation of signalingGO:00230562700.012
sodium ion transportGO:0006814820.012
purine nucleotide metabolic processGO:00061632290.012
cellular homeostasisGO:00197252520.012
positive regulation of phosphorylationGO:00423271770.012
amide transportGO:00428861050.012
intracellular protein transportGO:0006886790.012
positive regulation of cell morphogenesis involved in differentiationGO:0010770410.012
response to temperature stimulusGO:0009266940.012
sex differentiationGO:00075481130.012
response to electrical stimulusGO:0051602560.012
regulation of neuron apoptotic processGO:0043523830.012
positive regulation of response to stimulusGO:00485842850.012
cellular protein complex assemblyGO:0043623440.012
rho protein signal transductionGO:0007266110.012
regulation of respiratory system processGO:004406510.012
negative regulation of muscle cell apoptotic processGO:0010656210.012
response to fatty acidGO:0070542650.012
ion homeostasisGO:00508012120.011
peptide hormone secretionGO:0030072840.011
single organism membrane organizationGO:0044802740.011
response to interleukin 15GO:007067240.011
regulation of alternative mrna splicing via spliceosomeGO:000038120.011
cellular process involved in reproduction in multicellular organismGO:0022412350.011
regulation of dna metabolic processGO:0051052600.011
dendritic spine developmentGO:0060996200.011
blood circulationGO:00080151830.011
regulation of cardiac muscle contraction by calcium ion signalingGO:001088230.011
response to nicotineGO:0035094510.011
response to hexoseGO:00097461440.011
insulin secretionGO:0030073690.011
cellular response to oxygen levelsGO:0071453600.011
cell growthGO:00160491040.011
signal transduction involved in regulation of gene expressionGO:002301940.011
response to corticosteroidGO:00319602350.011
carbohydrate derivative catabolic processGO:19011361470.011
positive regulation of cellular amine metabolic processGO:003324030.011
divalent inorganic cation homeostasisGO:00725071650.011
cell cycleGO:00070491010.011
gliogenesisGO:0042063930.011
regulation of anatomical structure sizeGO:00900661350.011
gastrulationGO:000736920.011
metal ion homeostasisGO:00550651860.011
nitrogen compound transportGO:00717052290.011
positive regulation of homeostatic processGO:0032846490.011
rna localizationGO:000640340.011
development of primary female sexual characteristicsGO:0046545560.011
muscle cell differentiationGO:0042692520.011
cellular chemical homeostasisGO:00550822470.011
steroid metabolic processGO:0008202730.011
lung developmentGO:0030324430.011
regulation of immune system processGO:00026821230.011
regulation of secretionGO:00510462240.011
heart processGO:0003015570.011
developmental growth involved in morphogenesisGO:0060560330.011
regulation of transporter activityGO:0032409500.011
alpha amino acid metabolic processGO:1901605710.011
positive regulation of cytosolic calcium ion concentrationGO:00072041220.011
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
circadian regulation of gene expressionGO:003292230.011
negative regulation of neuron apoptotic processGO:0043524450.011
cellular response to growth factor stimulusGO:00713631620.011
regulation of ion transmembrane transporter activityGO:0032412480.011
response to estradiolGO:00323551640.011
peptidyl amino acid modificationGO:00181931260.011
positive regulation of cellular component movementGO:00512721020.011
positive regulation of locomotionGO:00400171020.011
regulation of bmp signaling pathwayGO:003051020.011
response to carbohydrateGO:00097431830.011
negative regulation of cell deathGO:00605482290.011
sensory organ developmentGO:0007423740.010
regulation of skeletal muscle tissue regenerationGO:004341620.010
negative regulation of rna metabolic processGO:00512531230.010
asymmetric protein localizationGO:000810520.010
negative regulation of cellular component organizationGO:0051129830.010
ribose phosphate metabolic processGO:00196932350.010
platelet aggregationGO:007052740.010
carbohydrate homeostasisGO:0033500750.010
salivary gland morphogenesisGO:000743510.010
negative regulation of signalingGO:00230571570.010
growthGO:00400071650.010
membrane depolarizationGO:0051899320.010

Sp4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.021
disease of cellular proliferationDOID:1456600.021
organ system cancerDOID:005068600.015
gastrointestinal system cancerDOID:311900.015
nervous system diseaseDOID:86300.012
disease of anatomical entityDOID:700.012
central nervous system diseaseDOID:33100.011