IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Clca5

chloride channel calcium activated 5

(Aliases: Clca2)

Entrez: 308016
Ensembl: ENSRNOG00000013771
RGD: 1304894
UniProtKB: D3ZVT7

Process Predictions
Disease Predictions

Clca5 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
carboxylic acid metabolic process	GO:0019752	289	0.107
response to nutrient levels	GO:0031667	370	0.094
cellular component assembly	GO:0022607	360	0.077
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.074
single organism reproductive process	GO:0044702	297	0.062
response to peptide hormone	GO:0043434	278	0.059
macromolecular complex assembly	GO:0065003	273	0.055
reproduction	GO:0000003	245	0.053
oxoacid metabolic process	GO:0043436	290	0.052
g protein coupled receptor signaling pathway	GO:0007186	242	0.052
reproductive process	GO:0022414	372	0.050
cellular response to oxygen containing compound	GO:1901701	386	0.050
response to external biotic stimulus	GO:0043207	221	0.049
response to extracellular stimulus	GO:0009991	380	0.048
positive regulation of cellular biosynthetic process	GO:0031328	295	0.047
regulation of catalytic activity	GO:0050790	304	0.046
kidney vasculature development	GO:0061440	6	0.046
response to wounding	GO:0009611	254	0.045
response to peptide	GO:1901652	292	0.044
protein complex assembly	GO:0006461	263	0.042
positive regulation of cell death	GO:0010942	184	0.040
cellular component biogenesis	GO:0044085	368	0.038
rna metabolic process	GO:0016070	406	0.038
multicellular organismal reproductive process	GO:0048609	233	0.038
tissue development	GO:0009888	252	0.038
protein homooligomerization	GO:0051260	91	0.037
organic acid metabolic process	GO:0006082	292	0.036
protein complex subunit organization	GO:0071822	302	0.036
response to nutrient	GO:0007584	248	0.036
regulation of apoptotic process	GO:0042981	335	0.035
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.035
positive regulation of biosynthetic process	GO:0009891	319	0.034
transcription dna templated	GO:0006351	377	0.034
transcription from rna polymerase ii promoter	GO:0006366	252	0.034
protein complex biogenesis	GO:0070271	263	0.033
programmed cell death	GO:0012501	392	0.033
macromolecule localization	GO:0033036	252	0.033
response to mineralocorticoid	GO:0051385	49	0.033
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.032
negative regulation of developmental process	GO:0051093	125	0.032
multi organism reproductive process	GO:0044703	262	0.032
positive regulation of rna biosynthetic process	GO:1902680	197	0.031
regulation of secretion by cell	GO:1903530	208	0.030
multicellular organism reproduction	GO:0032504	233	0.030
regulation of protein metabolic process	GO:0051246	289	0.030
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.030
apoptotic process	GO:0006915	381	0.029
metal ion transport	GO:0030001	289	0.029
macromolecular complex subunit organization	GO:0043933	339	0.029
proteolysis	GO:0006508	175	0.028
regulation of programmed cell death	GO:0043067	341	0.028
negative regulation of metabolic process	GO:0009892	331	0.028
negative regulation of molecular function	GO:0044092	133	0.028
positive regulation of multicellular organismal process	GO:0051240	387	0.028
lipid metabolic process	GO:0006629	283	0.027
sexual reproduction	GO:0019953	148	0.027
cellular cation homeostasis	GO:0030003	180	0.027
positive regulation of programmed cell death	GO:0043068	157	0.027
defense response	GO:0006952	194	0.027
inorganic ion transmembrane transport	GO:0098660	229	0.027	Mouse
regulation of hydrolase activity	GO:0051336	143	0.026
cellular amine metabolic process	GO:0044106	38	0.026
regulation of rna metabolic process	GO:0051252	391	0.026
positive regulation of transcription dna templated	GO:0045893	197	0.026
positive regulation of rna metabolic process	GO:0051254	203	0.026
anion transport	GO:0006820	178	0.026	Mouse
regulation of cell proliferation	GO:0042127	359	0.026
anatomical structure morphogenesis	GO:0009653	298	0.025
response to corticosteroid	GO:0031960	235	0.025
response to oxidative stress	GO:0006979	186	0.025
chemical homeostasis	GO:0048878	292	0.025
cell cell signaling	GO:0007267	335	0.025
response to bacterium	GO:0009617	200	0.024
cellular amino acid metabolic process	GO:0006520	107	0.024
response to biotic stimulus	GO:0009607	226	0.024
amine metabolic process	GO:0009308	38	0.024
single organism biosynthetic process	GO:0044711	342	0.024
intracellular signal transduction	GO:0035556	314	0.024
positive regulation of extracellular matrix constituent secretion	GO:0003331	2	0.023
response to other organism	GO:0051707	220	0.023
cellular response to endogenous stimulus	GO:0071495	377	0.023
hormone secretion	GO:0046879	115	0.023
glycosyl compound metabolic process	GO:1901657	182	0.023
regulation of secretion	GO:0051046	224	0.023
homeostatic process	GO:0042592	331	0.023
regulation of transcription dna templated	GO:0006355	374	0.022
response to radiation	GO:0009314	137	0.022
negative regulation of multicellular organismal process	GO:0051241	203	0.022
response to acid chemical	GO:0001101	222	0.022
response to lipopolysaccharide	GO:0032496	191	0.022
positive regulation of apoptotic process	GO:0043065	154	0.021
immune response	GO:0006955	104	0.021
negative regulation of gene expression	GO:0010629	199	0.021
positive regulation of extracellular matrix organization	GO:1903055	4	0.021
tongue morphogenesis	GO:0043587	3	0.020
nucleic acid templated transcription	GO:0097659	379	0.020
regulation of anatomical structure morphogenesis	GO:0022603	141	0.020
response to vitamin	GO:0033273	131	0.020
regulation of cellular component organization	GO:0051128	368	0.020
alpha amino acid metabolic process	GO:1901605	71	0.020
cell projection organization	GO:0030030	302	0.020
carbohydrate derivative metabolic process	GO:1901135	346	0.019
cell motility	GO:0048870	202	0.019
regulation of protein processing	GO:0070613	50	0.019
regulation of cellular amino acid metabolic process	GO:0006521	2	0.019
metal ion homeostasis	GO:0055065	186	0.019
alcohol metabolic process	GO:0006066	77	0.019
cell migration	GO:0016477	197	0.019
inflammatory response	GO:0006954	150	0.019
cellular response to organic cyclic compound	GO:0071407	202	0.018
positive regulation of cell proliferation	GO:0008284	249	0.018
unsaturated fatty acid metabolic process	GO:0033559	39	0.018
cellular chemical homeostasis	GO:0055082	247	0.018
regulation of cellular protein metabolic process	GO:0032268	267	0.018
organelle organization	GO:0006996	266	0.018
negative regulation of cellular metabolic process	GO:0031324	281	0.018
female pregnancy	GO:0007565	122	0.018
cellular ion homeostasis	GO:0006873	184	0.017
cytoskeleton organization	GO:0007010	111	0.017
single organism catabolic process	GO:0044712	283	0.017
regulation of cellular ketone metabolic process	GO:0010565	27	0.017
protein maturation	GO:0051604	68	0.017
negative regulation of protein maturation	GO:1903318	47	0.017
regulation of hormone levels	GO:0010817	187	0.017
response to glucocorticoid	GO:0051384	223	0.017
organic cyclic compound catabolic process	GO:1901361	175	0.017
mesoderm development	GO:0007498	2	0.017
single organism intracellular transport	GO:1902582	166	0.017
protein phosphorylation	GO:0006468	345	0.017
gamete generation	GO:0007276	124	0.016
cellular response to nitrogen compound	GO:1901699	210	0.016
regulation of molecular function	GO:0065009	398	0.016
response to transition metal nanoparticle	GO:1990267	122	0.016
cellular response to lipid	GO:0071396	201	0.016
protein localization	GO:0008104	191	0.016
response to growth factor	GO:0070848	189	0.016
negative regulation of programmed cell death	GO:0043069	183	0.016
cellular homeostasis	GO:0019725	252	0.016
gland development	GO:0048732	155	0.016
localization of cell	GO:0051674	202	0.016
positive regulation of developmental process	GO:0051094	283	0.015
regulation of rna biosynthetic process	GO:2001141	381	0.015
negative regulation of macromolecule metabolic process	GO:0010605	260	0.015
cellular response to growth factor stimulus	GO:0071363	162	0.015
negative regulation of protein metabolic process	GO:0051248	114	0.015
negative regulation of cell death	GO:0060548	229	0.015
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.015
circulatory system development	GO:0072359	134	0.015
negative regulation of catalytic activity	GO:0043086	103	0.015
nucleobase containing small molecule metabolic process	GO:0055086	316	0.015
regulation of protein maturation	GO:1903317	50	0.015
urogenital system development	GO:0001655	78	0.015
nitrogen compound transport	GO:0071705	229	0.015
positive regulation of cell differentiation	GO:0045597	217	0.015
purine ribonucleoside metabolic process	GO:0046128	168	0.015
growth	GO:0040007	165	0.015
wound healing	GO:0042060	122	0.015
extracellular matrix constituent secretion	GO:0070278	4	0.015
cation homeostasis	GO:0055080	195	0.015
regulation of cellular amine metabolic process	GO:0033238	8	0.015
cellular response to hormone stimulus	GO:0032870	247	0.014
catabolic process	GO:0009056	351	0.014
protein processing	GO:0016485	68	0.014
response to ketone	GO:1901654	182	0.014
cellular nitrogen compound catabolic process	GO:0044270	163	0.014
cellular lipid metabolic process	GO:0044255	208	0.014
acid secretion	GO:0046717	48	0.014
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.014
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.014
rna biosynthetic process	GO:0032774	380	0.014
axis specification	GO:0009798	4	0.014
regulation of cell differentiation	GO:0045595	320	0.014
positive regulation of gene expression	GO:0010628	244	0.014
cytosolic calcium ion homeostasis	GO:0051480	140	0.014
positive regulation of cellular component organization	GO:0051130	200	0.014
neuron development	GO:0048666	286	0.014
peptidyl amino acid modification	GO:0018193	126	0.014
protein oligomerization	GO:0051259	191	0.014
secretion by cell	GO:0032940	248	0.014
cation transport	GO:0006812	382	0.014
response to purine containing compound	GO:0014074	126	0.014
negative regulation of cell proliferation	GO:0008285	119	0.014
neuron projection development	GO:0031175	273	0.014
secretion	GO:0046903	307	0.013
cellular component movement	GO:0006928	248	0.013
cellular ketone metabolic process	GO:0042180	51	0.013
cellular calcium ion homeostasis	GO:0006874	160	0.013
response to inorganic substance	GO:0010035	377	0.013
positive regulation of cellular component movement	GO:0051272	102	0.013
monovalent inorganic cation transport	GO:0015672	172	0.013
organophosphate metabolic process	GO:0019637	370	0.013
purine nucleoside metabolic process	GO:0042278	169	0.013
organic acid biosynthetic process	GO:0016053	83	0.013
response to reactive oxygen species	GO:0000302	120	0.013
regulation of proteolysis	GO:0030162	66	0.013
gap junction assembly	GO:0016264	2	0.013
renal system development	GO:0072001	67	0.013
nucleotide metabolic process	GO:0009117	279	0.012
single organism cellular localization	GO:1902580	102	0.012
positive regulation of catalytic activity	GO:0043085	184	0.012
calcium ion homeostasis	GO:0055074	162	0.012
cellular catabolic process	GO:0044248	295	0.012
nucleoside metabolic process	GO:0009116	179	0.012
regulation of extracellular matrix constituent secretion	GO:0003330	2	0.012
response to decreased oxygen levels	GO:0036293	237	0.012	Rat
vesicle mediated transport	GO:0016192	181	0.012
divalent inorganic cation homeostasis	GO:0072507	165	0.012
negative regulation of fibrinolysis	GO:0051918	2	0.012
regulation of system process	GO:0044057	208	0.012
purine containing compound metabolic process	GO:0072521	253	0.012
fatty acid derivative metabolic process	GO:1901568	38	0.012
positive regulation of transport	GO:0051050	245	0.012
cellular response to acid chemical	GO:0071229	75	0.012
positive regulation of protein metabolic process	GO:0051247	178	0.012
regeneration	GO:0031099	163	0.012
lipid catabolic process	GO:0016042	46	0.012
response to molecule of bacterial origin	GO:0002237	194	0.012
negative regulation of transcription dna templated	GO:0045892	116	0.012
nucleobase containing compound catabolic process	GO:0034655	152	0.011
inorganic cation transmembrane transport	GO:0098662	202	0.011
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.011
hormone transport	GO:0009914	121	0.011
positive regulation of molecular function	GO:0044093	230	0.011
negative regulation of cellular biosynthetic process	GO:0031327	161	0.011
positive regulation of signaling	GO:0023056	270	0.011
locomotion	GO:0040011	237	0.011
single organism organelle organization	GO:1902589	180	0.011
negative regulation of secretion	GO:0051048	82	0.011
lipid transport	GO:0006869	61	0.011
developmental process involved in reproduction	GO:0003006	159	0.011
negative regulation of apoptotic process	GO:0043066	181	0.011
organonitrogen compound catabolic process	GO:1901565	179	0.011
regulation of gtpase activity	GO:0043087	57	0.011
transmission of nerve impulse	GO:0019226	42	0.011
response to ethanol	GO:0045471	162	0.011
regulation of vasculature development	GO:1901342	44	0.011
response to molecule of fungal origin	GO:0002238	3	0.011
lipid biosynthetic process	GO:0008610	128	0.011
organic substance catabolic process	GO:1901575	316	0.011
monocarboxylic acid transport	GO:0015718	52	0.011
lipid localization	GO:0010876	62	0.011
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.011
ras protein signal transduction	GO:0007265	29	0.011
action potential	GO:0001508	54	0.011
response to hexose	GO:0009746	144	0.010
ribonucleoside metabolic process	GO:0009119	174	0.010
fertilization	GO:0009566	3	0.010
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.010
cellular metal ion homeostasis	GO:0006875	172	0.010
response to retinoic acid	GO:0032526	63	0.010
heterocycle catabolic process	GO:0046700	167	0.010
cellular response to corticosteroid stimulus	GO:0071384	69	0.010
carboxylic acid biosynthetic process	GO:0046394	83	0.010
fatty acid metabolic process	GO:0006631	99	0.010
spermatogenesis	GO:0007283	99	0.010
lipid storage	GO:0019915	1	0.010
hematopoietic progenitor cell differentiation	GO:0002244	2	0.010
negative regulation of protein processing	GO:0010955	47	0.010
regulation of body fluid levels	GO:0050878	90	0.010
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.010
response to fatty acid	GO:0070542	65	0.010
multicellular organismal signaling	GO:0035637	44	0.010

Clca5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.018
disease of anatomical entity	DOID:7	0.015
nervous system disease	DOID:863	0.015

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